BACKGROUND Painless gastroscopy is a widely used diagnostic and therapeutic technology in clinical practice.Propofol combined with opioids is a common drug for painless endoscopic sedation and anaesthesia.In clinical ...BACKGROUND Painless gastroscopy is a widely used diagnostic and therapeutic technology in clinical practice.Propofol combined with opioids is a common drug for painless endoscopic sedation and anaesthesia.In clinical work,adverse drug reactions of anaesthesia schemes are often one of the important areas of concern for doctors and patients.With the increase in propofol dosage,the risk of serious adverse drug reactions,such as respiratory depression and hypotension,increases significantly;the use of opioids often causes gastrointestinal reactions in patients after examination,such as nausea,vomiting,delayed recovery of gastrointestinal function and other complications,which seriously affect their quality of life.AIM To observe the effect of wrist-ankle acupuncture therapy on the anaesthesia regimen and anaesthesia-related complications during and after painless gastroscopy examination.METHODS Two hundred patients were selected and randomly divided into a treatment group(n=100)and a control group(n=100).Both groups were routinely anaesthetized with the nalbuphine and propofol regimen,gastroscopy began after the patient lost consciousness,and given supportive treatment and vital sign monitoring.If the patient interrupted the surgery due to intraoperative torsion,intravenous propofol was used to relieve his or her discomfort.The treatment group received wrist-ankle acupuncture on this basis.RESULTS The general data before treatment,American Society of Anesthesiologist(ASA)grade and operation time between the two groups was no significant difference.The Wakeup time,and the Selfambulation time in the treatment group was significantly faster than that in the control group(P<0.05).The total dose of propofol in the treatment group was 109±8.17 mg,significantly lower than that in the control group(P<0.05).The incidence of respiratory depression and hypotension was not significantly different,but the incidence of hiccups was significantly lower than that in the control group(P<0.05).After the examination,the incidence of nausea,vomiting,abdominal distension,and abdominal pain was 11%,8%,6%,and 5%,respectively,which was significantly lower than that in the control group(P<0.05).In addition,both the operators and the patients were more satisfied with this examination,with no significant difference between the groups(P>0.05).CONCLUSION Wrist-ankle acupuncture treatment can optimize the painless gastroscopy and anaesthesia scheme,reduces propofol total dose;shortens patient Wakeup time and Self-ambulation time,improves patient compliance and tolerance,is beneficial to clinical application.展开更多
Objective:To observe the Effective dose and safety of different doses of alfentanil combined with propofol in painless gastroscopy.Method:240 patients who underwent painless gastric examination from January 2021 to De...Objective:To observe the Effective dose and safety of different doses of alfentanil combined with propofol in painless gastroscopy.Method:240 patients who underwent painless gastric examination from January 2021 to December 2021 were randomly divided into a control group and a different dose group of alfentanil(N1 group,N2 group,N3 group,N4 group,and N5 group,with injection doses of 5,6,7,8,and 10ug/kg,respectively)using a number table method,with 40 patients in each group.The control group was anesthetized with propofol injection,while different dosage groups of alfentanil were anesthetized with different doses of alfentanil combined with propofol.Evaluate the anesthesia effect after the examination is completed.Compare the heart rate(HR),systolic blood pressure(SBP),apnea time,incidence of intolerance to gastroscopy insertion,and adverse reactions in each group.Result:Compared with before administration,SBP and HR in all groups decreased before gastroscopy placement(P<0.01);At 1 minute after gastroscopy insertion,both SBP and HR in the control group increased(P<0.01),while SBP in the N3 and N4 groups decreased(P<0.01),while HR remained unchanged(P>0.05).Both SBP and HR in the N5 group decreased(P<0.01).Compared with before gastroscopy insertion,SBP and HR in the control group,N1,N2,and N3 groups increased 1 minute after gastroscopy insertion(P<0.01),while there was no significant change in SBP and HR in the N4 and N5 groups(P>0.05).The apnea time of different dosage groups of alfentanil was lower than that of the control group(P<0.01),and the apnea time of N5 group was higher than that of N1 group,N2 group,N3 group,and N4 group(P<0.01).There was no significant difference in the Incidence of intolerant reactions during gastroscopy insertion,cough reaction,retching reflex,swallowing reflex and limb movement reaction rate between the six groups(P>0.05);There was no statistically significant difference in the incidence of itching,nausea,vomiting,anxiety,dizziness,drowsiness,diarrhea,and constipation after painless gastroscopy examination among the six groups(P>0.05).Conclusion:The combination of 8ug/kg alfentanil and propofol has a definite anesthesia effect,stable respiratory and circulatory system,and low incidence of adverse reactions when used for painless gastroscopy.展开更多
Objective: to analyze the negative emotional impact of this treatment on patients undergoing health examination. The period is from January 2020 to January 2021. A total of 70 patients were selected for painless gastr...Objective: to analyze the negative emotional impact of this treatment on patients undergoing health examination. The period is from January 2020 to January 2021. A total of 70 patients were selected for painless gastroscopy in our hospital. All patients were randomly divided into two groups. There were 35 cases in observation group and 35 cases in control group. Compared with the traditional way of nursing, this group used convenient nursing to compare the negative emotions before and after nursing between the two groups. Compared with the obtained data, the nursing satisfaction of the observation group was 34 cases (97.14%), significantly higher than that of the control group of 29 cases (82.86%), SAS score (41.34±6.5), SDS score (42.39±7.3). After nursing, the scores of SAS (53.75±5.3) and SDS (51.51±7.2) in the control group were significantly better than those in the control group, and the differences were statistically significant (P < 0.05). Conclusion: comfortable nursing for patients with painless gastroscopy can not only effectively improve patients' satisfaction with nursing, but also improve their bad mood. It has important practical significance and can be widely used.展开更多
Objective: to observe the clinical effect of propofol and etomidate mixture combined with butorphanol tartrate in painless gastroscopy. Methods: 90 patients undergoing painless gastroscopy were randomly divided into t...Objective: to observe the clinical effect of propofol and etomidate mixture combined with butorphanol tartrate in painless gastroscopy. Methods: 90 patients undergoing painless gastroscopy were randomly divided into three groups. Group P: propofol 2mg / kg;Group E: etomidate 0.3mg/kg;Group PE: propofol and etomidate mixture (10mg∶2mg). Three groups were given butorphanol 10 μg/kg intravenous injection slowly 3 minutes before gastroscopy. The changes of MAP, HR, SpO2, incidence of adverse reactions, induction time and awakening time were observed and recorded before, during and 5 min after the examination. Results: there was no significant difference in the induction time and awakening time among the groups (P > 0.05). In terms of hemodynamics, MAP and HR during and after operation in group P were lower than those in group E and group PE (P < 0.05). The incidence of intravenous pain and respiratory depression in group P was higher than that in group E and PE (P < 0.05). The incidence of body moving and muscular fibrillation, nausea and vomiting in group E was higher than that in group P and group PE, and the incidence of body movement, nausea and vomiting and muscle fibrillation in group PE was the lowest, the breathing cycle is more stable. Conclusion: propofol and etomidate mixture combined with butorphanol in painless gastroscopy has more stable respiratory circulation, lower incidence of adverse reactions, safer and more comfortable examination process, and higher satisfaction of patients.展开更多
Objective: To investigate the clinical effect of propofol combined with Butorphanol in painless gastroscopy anesthesia. Methods: from January 2020 to June 2020, 137 patients with painless gastroscopy were randomly div...Objective: To investigate the clinical effect of propofol combined with Butorphanol in painless gastroscopy anesthesia. Methods: from January 2020 to June 2020, 137 patients with painless gastroscopy were randomly divided into two groups. The control group was given propofol combined anesthesia, and the observation group was given propofol combined butorphanol anesthesia. Gastroscopy was performed after eyelash reflex disappeared. The total effective rate of anesthesia, disappearance time of eyelash reflex, recovery time and dosage of propofol were compared between the two groups. Results: the total effective rate of anesthesia in the observation group (100.0%) was significantly higher than that in the control group (92.75%), the difference was statistically significant (P < 0.05). There was no significant difference in the disappearance time and recovery time of eyelash reflex between the observation group and the control group (P > 0.05), but the average dosage of propofol in the observation group was (1.76 ± 0.56) mg / kg, which was significantly lower than (2.63 ± 0.49) mg / kg in the control group (P < 0.05). Conclusion: the clinical effect of propofol combined with Butorphanol in outpatient painless gastroscopy anesthesia is significant, which can effectively improve the anesthesia efficiency of patients with painless gastroscopy anesthesia and reduce the average dosage of propofol, which is worthy of clinical promotion.展开更多
Objective: to evaluate the clinical effects of painless gastroscopy in gastroenterology patients. Methods: a total of 100 patients treated in the department of gastroenterology of our hospital were selected as the sub...Objective: to evaluate the clinical effects of painless gastroscopy in gastroenterology patients. Methods: a total of 100 patients treated in the department of gastroenterology of our hospital were selected as the subjects of this study. The 100 patients were selected from January 2020 to December 2020, and the patients were randomly assigned to the same number of patients in the research group and the reference group. The 50 patients undergoing routine gastroenteroscopy in our hospital were set as the reference group. A total of 50 patients treated with painless gastroenteroscopy were selected as the study group. Statistical analysis was performed on the operation and discharge time, the occurrence of adverse reactions and the therapeutic effect of patients in the two groups. Results: after comparing the recorded data, it was found that the data of study group were better than the control group in terms of operation time, discharge time, occurrence of adverse reactions and treatment effect (P < 0.05). Conclusion: in the treatment of digestive diseases, treatment for patients with digestive internal medicine in painless gastrointestinal mirror, can make the patients obviously shorten the hospitalization time, at the time of surgery in patients with significantly shorten the operation time and regular treatment, the clinical treatment effect is better, effectively reduce the diagnosis and treatment of patients with adverse situation, has the promotion value.Keywords: painless gastroscopy;digestive diseases;clinical analysis展开更多
基金Supported by Xiamen Medical and Health Guidance Project Section,No.3502Z20224ZD1169Xiamen sixth batch of TCM Reserve Talent Training Project,No.136,2022.
文摘BACKGROUND Painless gastroscopy is a widely used diagnostic and therapeutic technology in clinical practice.Propofol combined with opioids is a common drug for painless endoscopic sedation and anaesthesia.In clinical work,adverse drug reactions of anaesthesia schemes are often one of the important areas of concern for doctors and patients.With the increase in propofol dosage,the risk of serious adverse drug reactions,such as respiratory depression and hypotension,increases significantly;the use of opioids often causes gastrointestinal reactions in patients after examination,such as nausea,vomiting,delayed recovery of gastrointestinal function and other complications,which seriously affect their quality of life.AIM To observe the effect of wrist-ankle acupuncture therapy on the anaesthesia regimen and anaesthesia-related complications during and after painless gastroscopy examination.METHODS Two hundred patients were selected and randomly divided into a treatment group(n=100)and a control group(n=100).Both groups were routinely anaesthetized with the nalbuphine and propofol regimen,gastroscopy began after the patient lost consciousness,and given supportive treatment and vital sign monitoring.If the patient interrupted the surgery due to intraoperative torsion,intravenous propofol was used to relieve his or her discomfort.The treatment group received wrist-ankle acupuncture on this basis.RESULTS The general data before treatment,American Society of Anesthesiologist(ASA)grade and operation time between the two groups was no significant difference.The Wakeup time,and the Selfambulation time in the treatment group was significantly faster than that in the control group(P<0.05).The total dose of propofol in the treatment group was 109±8.17 mg,significantly lower than that in the control group(P<0.05).The incidence of respiratory depression and hypotension was not significantly different,but the incidence of hiccups was significantly lower than that in the control group(P<0.05).After the examination,the incidence of nausea,vomiting,abdominal distension,and abdominal pain was 11%,8%,6%,and 5%,respectively,which was significantly lower than that in the control group(P<0.05).In addition,both the operators and the patients were more satisfied with this examination,with no significant difference between the groups(P>0.05).CONCLUSION Wrist-ankle acupuncture treatment can optimize the painless gastroscopy and anaesthesia scheme,reduces propofol total dose;shortens patient Wakeup time and Self-ambulation time,improves patient compliance and tolerance,is beneficial to clinical application.
基金Hubei Chen Xiaoping Science and Technology Development Foundation for Perioperative analgesic Afentanil Special Fund(No.CXPJJH12000010)Health Industry Research Project of Hainan Province(No.20A200263)。
文摘Objective:To observe the Effective dose and safety of different doses of alfentanil combined with propofol in painless gastroscopy.Method:240 patients who underwent painless gastric examination from January 2021 to December 2021 were randomly divided into a control group and a different dose group of alfentanil(N1 group,N2 group,N3 group,N4 group,and N5 group,with injection doses of 5,6,7,8,and 10ug/kg,respectively)using a number table method,with 40 patients in each group.The control group was anesthetized with propofol injection,while different dosage groups of alfentanil were anesthetized with different doses of alfentanil combined with propofol.Evaluate the anesthesia effect after the examination is completed.Compare the heart rate(HR),systolic blood pressure(SBP),apnea time,incidence of intolerance to gastroscopy insertion,and adverse reactions in each group.Result:Compared with before administration,SBP and HR in all groups decreased before gastroscopy placement(P<0.01);At 1 minute after gastroscopy insertion,both SBP and HR in the control group increased(P<0.01),while SBP in the N3 and N4 groups decreased(P<0.01),while HR remained unchanged(P>0.05).Both SBP and HR in the N5 group decreased(P<0.01).Compared with before gastroscopy insertion,SBP and HR in the control group,N1,N2,and N3 groups increased 1 minute after gastroscopy insertion(P<0.01),while there was no significant change in SBP and HR in the N4 and N5 groups(P>0.05).The apnea time of different dosage groups of alfentanil was lower than that of the control group(P<0.01),and the apnea time of N5 group was higher than that of N1 group,N2 group,N3 group,and N4 group(P<0.01).There was no significant difference in the Incidence of intolerant reactions during gastroscopy insertion,cough reaction,retching reflex,swallowing reflex and limb movement reaction rate between the six groups(P>0.05);There was no statistically significant difference in the incidence of itching,nausea,vomiting,anxiety,dizziness,drowsiness,diarrhea,and constipation after painless gastroscopy examination among the six groups(P>0.05).Conclusion:The combination of 8ug/kg alfentanil and propofol has a definite anesthesia effect,stable respiratory and circulatory system,and low incidence of adverse reactions when used for painless gastroscopy.
文摘Objective: to analyze the negative emotional impact of this treatment on patients undergoing health examination. The period is from January 2020 to January 2021. A total of 70 patients were selected for painless gastroscopy in our hospital. All patients were randomly divided into two groups. There were 35 cases in observation group and 35 cases in control group. Compared with the traditional way of nursing, this group used convenient nursing to compare the negative emotions before and after nursing between the two groups. Compared with the obtained data, the nursing satisfaction of the observation group was 34 cases (97.14%), significantly higher than that of the control group of 29 cases (82.86%), SAS score (41.34±6.5), SDS score (42.39±7.3). After nursing, the scores of SAS (53.75±5.3) and SDS (51.51±7.2) in the control group were significantly better than those in the control group, and the differences were statistically significant (P < 0.05). Conclusion: comfortable nursing for patients with painless gastroscopy can not only effectively improve patients' satisfaction with nursing, but also improve their bad mood. It has important practical significance and can be widely used.
文摘Objective: to observe the clinical effect of propofol and etomidate mixture combined with butorphanol tartrate in painless gastroscopy. Methods: 90 patients undergoing painless gastroscopy were randomly divided into three groups. Group P: propofol 2mg / kg;Group E: etomidate 0.3mg/kg;Group PE: propofol and etomidate mixture (10mg∶2mg). Three groups were given butorphanol 10 μg/kg intravenous injection slowly 3 minutes before gastroscopy. The changes of MAP, HR, SpO2, incidence of adverse reactions, induction time and awakening time were observed and recorded before, during and 5 min after the examination. Results: there was no significant difference in the induction time and awakening time among the groups (P > 0.05). In terms of hemodynamics, MAP and HR during and after operation in group P were lower than those in group E and group PE (P < 0.05). The incidence of intravenous pain and respiratory depression in group P was higher than that in group E and PE (P < 0.05). The incidence of body moving and muscular fibrillation, nausea and vomiting in group E was higher than that in group P and group PE, and the incidence of body movement, nausea and vomiting and muscle fibrillation in group PE was the lowest, the breathing cycle is more stable. Conclusion: propofol and etomidate mixture combined with butorphanol in painless gastroscopy has more stable respiratory circulation, lower incidence of adverse reactions, safer and more comfortable examination process, and higher satisfaction of patients.
文摘Objective: To investigate the clinical effect of propofol combined with Butorphanol in painless gastroscopy anesthesia. Methods: from January 2020 to June 2020, 137 patients with painless gastroscopy were randomly divided into two groups. The control group was given propofol combined anesthesia, and the observation group was given propofol combined butorphanol anesthesia. Gastroscopy was performed after eyelash reflex disappeared. The total effective rate of anesthesia, disappearance time of eyelash reflex, recovery time and dosage of propofol were compared between the two groups. Results: the total effective rate of anesthesia in the observation group (100.0%) was significantly higher than that in the control group (92.75%), the difference was statistically significant (P < 0.05). There was no significant difference in the disappearance time and recovery time of eyelash reflex between the observation group and the control group (P > 0.05), but the average dosage of propofol in the observation group was (1.76 ± 0.56) mg / kg, which was significantly lower than (2.63 ± 0.49) mg / kg in the control group (P < 0.05). Conclusion: the clinical effect of propofol combined with Butorphanol in outpatient painless gastroscopy anesthesia is significant, which can effectively improve the anesthesia efficiency of patients with painless gastroscopy anesthesia and reduce the average dosage of propofol, which is worthy of clinical promotion.
文摘Objective: to evaluate the clinical effects of painless gastroscopy in gastroenterology patients. Methods: a total of 100 patients treated in the department of gastroenterology of our hospital were selected as the subjects of this study. The 100 patients were selected from January 2020 to December 2020, and the patients were randomly assigned to the same number of patients in the research group and the reference group. The 50 patients undergoing routine gastroenteroscopy in our hospital were set as the reference group. A total of 50 patients treated with painless gastroenteroscopy were selected as the study group. Statistical analysis was performed on the operation and discharge time, the occurrence of adverse reactions and the therapeutic effect of patients in the two groups. Results: after comparing the recorded data, it was found that the data of study group were better than the control group in terms of operation time, discharge time, occurrence of adverse reactions and treatment effect (P < 0.05). Conclusion: in the treatment of digestive diseases, treatment for patients with digestive internal medicine in painless gastrointestinal mirror, can make the patients obviously shorten the hospitalization time, at the time of surgery in patients with significantly shorten the operation time and regular treatment, the clinical treatment effect is better, effectively reduce the diagnosis and treatment of patients with adverse situation, has the promotion value.Keywords: painless gastroscopy;digestive diseases;clinical analysis
