A class of generalized vector variational-type inequality problems (GVVTIP) are studied in FC-spaces, which includes the most of vector equilibrium problems, vector variational inequality problems, generalized vecto...A class of generalized vector variational-type inequality problems (GVVTIP) are studied in FC-spaces, which includes the most of vector equilibrium problems, vector variational inequality problems, generalized vector equilibrium problems and general- ized vector variational inequality problem as special cases. By using F-KKM theorem, some new existence results for GVVTIP axe established in noncompact FC-space. As consequences, some recent known results in literature are obtained under much weaker assumption.展开更多
基金Project supported by the Natural Science Foundation of Sichuan Education Department of China(No.2003A081)
文摘A class of generalized vector variational-type inequality problems (GVVTIP) are studied in FC-spaces, which includes the most of vector equilibrium problems, vector variational inequality problems, generalized vector equilibrium problems and general- ized vector variational inequality problem as special cases. By using F-KKM theorem, some new existence results for GVVTIP axe established in noncompact FC-space. As consequences, some recent known results in literature are obtained under much weaker assumption.
文摘目的探讨参地益阴胶囊联合维格列汀片治疗2型糖尿病的临床疗效。方法选取2017年2月—2018年2月在西安市第九医院治疗的2型糖尿病患者92例,根据用药的差别分为对照组(46例)和治疗组(46例)。对照组口服维格列汀片,50 mg/次,2次/d;治疗组在对照组基础上口服参地益阴胶囊,4粒/次,3次/d。两组患者均治疗3个月。观察两组患者临床疗效,同时比较治疗前后两组患者血糖相关指标、血清学指标和氧化应激指标。结果治疗后,对照组临床有效率为80.43%,显著低于治疗组的95.65%,两组比较差异具有统计学意义(P<0.05)。治疗后,两组空腹血糖(FBG)、餐后2h血糖(2 h PG)、糖化血红蛋白(Hb A1c)、空腹胰岛素(FINS)水平均显著降低(P<0.05),且治疗组这些血糖相关指标比对照组降低更明显(P<0.05)。治疗后,两组血小板源性生长因子(PGRN)、γ-谷氨酰转肽酶(γ-GT)、转化生长因子-β1(TGF-β1)水平均显著降低(P<0.05),分泌型卷曲相关蛋白5(SFRP5)水平显著增加(P<0.05),且治疗后治疗组这些血清学指标明显优于对照组(P<0.05)。治疗后,两组谷胱甘肽过氧化物酶(GSH-PX)、超氧化物歧化酶(SOD)水平均显著升高(P<0.05),丙二醛(MDA)水平显著降低(P<0.05),且治疗后治疗组上述氧化应激指标改善程度明显优于对照组(P<0.05)。结论参地益阴胶囊联合维格列汀片治疗2型糖尿病可有效降低机体炎症反应,改善氧化应激状态,具有一定的临床推广应用价值。