In nature,certain plants exhibit“sleep”behaviors,such as leaves opening during the day and closing at night[1],which is synchronized with the human circadian rhythm.Traditional Chinese medicine(TCM)describes this ph...In nature,certain plants exhibit“sleep”behaviors,such as leaves opening during the day and closing at night[1],which is synchronized with the human circadian rhythm.Traditional Chinese medicine(TCM)describes this phenomenon as the plant's“diurnal opening and nocturnal closing”trait.Peanut stems and leaves(PSL)refers to the stems and leaves of the leguminous plant Arachis hypogaea L.,which displays this characteristic.PSL has been used as a traditional herbal medicine in TCM for treating insomnia,it was recommended by the Chinese Sleep Research Society's Insomnia Diagnosis and Treatment Guidelines as a recommended monotherapy for treating insomnia in primary healthcare institutions in 2024[2].Based on this,our research group developed a TCM formulation from PSL,named Luo Hua An Shen Oral Liquid(LAOL),which has been clinically applied for over 40 years to treat insomnia.Numerous clinical studies have shown that taking PSL before bedtime promotes sleep[3],while daytime administration enhances daytime functioning.Moreover,our findings demonstrate that the therapeutic efficacy of PSL is independent of administration dosage,administration frequency,and moderate-to-vigorous intensity physical activity.展开更多
鉴于传统径基函数网络(radial basis function network,简称RBFN)构造策略的不足,提出了基于偏最小二乘法(partial least squares,简称PLS)和遗传算法(genetic algorithms,简称GAs)的RBFN构造策略和一种更有效的径基宽度取值方法.在这...鉴于传统径基函数网络(radial basis function network,简称RBFN)构造策略的不足,提出了基于偏最小二乘法(partial least squares,简称PLS)和遗传算法(genetic algorithms,简称GAs)的RBFN构造策略和一种更有效的径基宽度取值方法.在这个集成构造策略中,PLS克服了K-Means算法求取径基易陷入局部最优的弊病,并使合成径基比由正交算法获取的径基更具代表性;而所提出的径基宽度取值方法和GAs则为网络性能和结构的实质性改善与优化提供了保障.实验证实了基于PLS和GAs的RBFN构造策略及所提出的径基宽度取值方法的优越性、可靠性和有效性.展开更多
In this paper, in order to find a set of element orders of projective special liner group PSL(2,q) and num-bers of elements every order and order of group,we give a search algorithm and discuss complexity of the algor...In this paper, in order to find a set of element orders of projective special liner group PSL(2,q) and num-bers of elements every order and order of group,we give a search algorithm and discuss complexity of the algorithm.展开更多
基金supported by the National Key R&D Program of China(Grant No.:2021YFC2501500)Shanghai Key Laboratory for Pharmaceutical Metabolite Research,China(Grant No.:SHZYDX2023-01)Shanghai Technical Superiority Project of"Preventive Treatment of Disease",Shanghai Municipal Health Commission,China(Grant No.:ZY(2021-2023)-0104-02-GF-04).
文摘In nature,certain plants exhibit“sleep”behaviors,such as leaves opening during the day and closing at night[1],which is synchronized with the human circadian rhythm.Traditional Chinese medicine(TCM)describes this phenomenon as the plant's“diurnal opening and nocturnal closing”trait.Peanut stems and leaves(PSL)refers to the stems and leaves of the leguminous plant Arachis hypogaea L.,which displays this characteristic.PSL has been used as a traditional herbal medicine in TCM for treating insomnia,it was recommended by the Chinese Sleep Research Society's Insomnia Diagnosis and Treatment Guidelines as a recommended monotherapy for treating insomnia in primary healthcare institutions in 2024[2].Based on this,our research group developed a TCM formulation from PSL,named Luo Hua An Shen Oral Liquid(LAOL),which has been clinically applied for over 40 years to treat insomnia.Numerous clinical studies have shown that taking PSL before bedtime promotes sleep[3],while daytime administration enhances daytime functioning.Moreover,our findings demonstrate that the therapeutic efficacy of PSL is independent of administration dosage,administration frequency,and moderate-to-vigorous intensity physical activity.
文摘鉴于传统径基函数网络(radial basis function network,简称RBFN)构造策略的不足,提出了基于偏最小二乘法(partial least squares,简称PLS)和遗传算法(genetic algorithms,简称GAs)的RBFN构造策略和一种更有效的径基宽度取值方法.在这个集成构造策略中,PLS克服了K-Means算法求取径基易陷入局部最优的弊病,并使合成径基比由正交算法获取的径基更具代表性;而所提出的径基宽度取值方法和GAs则为网络性能和结构的实质性改善与优化提供了保障.实验证实了基于PLS和GAs的RBFN构造策略及所提出的径基宽度取值方法的优越性、可靠性和有效性.
文摘In this paper, in order to find a set of element orders of projective special liner group PSL(2,q) and num-bers of elements every order and order of group,we give a search algorithm and discuss complexity of the algorithm.
