目的探究PROS1基因单核苷酸多态性(SNP)与包头地区汉族人群复发性流产(RSA)发生风险之间的相关性。方法选取RSA患者及对照人群各158例作为研究对象,测定蛋白S、蛋白C、抗凝血酶-Ⅲ活性;使用聚合酶链式反应-限制性片段长度多态性(PCR-RF...目的探究PROS1基因单核苷酸多态性(SNP)与包头地区汉族人群复发性流产(RSA)发生风险之间的相关性。方法选取RSA患者及对照人群各158例作为研究对象,测定蛋白S、蛋白C、抗凝血酶-Ⅲ活性;使用聚合酶链式反应-限制性片段长度多态性(PCR-RFLP)技术对PROS1基因rs13062355、rs6441600和rs12634349位点进行基因分型。采用非条件性Logistic回归分析PROS1基因三种SNP与RSA发生风险的相关性。结果RSA患者的蛋白S、抗凝血酶-Ⅲ活性下降(P<0.05);PROS1 SNP rs13062355在显性模型下与RSA发病风险相关:与携带TT基因型患者比较,携带CT+CC基因型的患者RSA发病风险下降(OR=0.398,95%CI:0.249~0.638)。SNP rs6441600、rs12634349与RSA的发病风险无关联。在PROS1 rs13062355、rs6441600、rs12634349构建的单体型中,单体型C-C-C在两组间差异有统计学意义(P<0.05);三阶交互模型rs13062355-rs6441600-rs12634349与RSA发病风险相关。结论PROS1 SNP rs13062355可能与包头地区汉族女性RSA患病风险相关;PROS1 rs13062355、rs6441600、rs12634349的单体型C-C-C降低了RSA发病风险;三阶模型rs13062355-rs6441600-rs12634349的交互作用在RSA的发生中具有协同效应。展开更多
The current system of Chinese medicine education is centered on institutional education,teacher-training education,and continuing education,and it has realized the dynamic match between the supply of talents and the d...The current system of Chinese medicine education is centered on institutional education,teacher-training education,and continuing education,and it has realized the dynamic match between the supply of talents and the demand of the industry through large-scale cultivation,innovative teacher-training integration,and multi-dimensional continuing education.However,there are still problems such as the disconnection between the theory and practice of institutional education,the limited development of teacher-training education on a large scale,the uneven quality of continuing education,the conflict of combined education of traditional Chinese medicine and Western medicine,and the obstruction of internationalized education.This paper proposes to reconstruct the institutional curriculum system,innovate the stratified classification system of teacher training,strengthen the practice orientation of continuing education,promote the in-depth integration of Chinese and Western medicine,and improve the policy guarantee mechanism,and other improvement paths,aiming to build a new type of Chinese medicine personnel training system that emphasizes both classical inheritance and modern innovation,and the complementarity between institutional education and teacher training,so as to provide a decision-making reference for the sustainable development of Chinese medicine education.展开更多
Photocatalysis is an advanced oxidation process where light exposure triggers a semiconducting nanomaterial(nano-photocatalyst)to generate electron-hole(e^(-)/h^(+))pairs and free radicals.This phenomenon is widely us...Photocatalysis is an advanced oxidation process where light exposure triggers a semiconducting nanomaterial(nano-photocatalyst)to generate electron-hole(e^(-)/h^(+))pairs and free radicals.This phenomenon is widely used for the photocatalysis-assisted removal of organic and other contaminants using wide range of nanophotocatalysts,offering an efficient approach to environmental remediation.However,the introduction of powdered nano-photocatalysts into water systems often leads to unintended secondary pollution in the form of residual nano-photocatalysts,ion leaching,free radicals,toxic by-products etc.Such practices potentially introduce emerging secondary contaminants into aquatic environments,posing risks to both aquatic life and human health.The resulting chemical by-products and intermediates can effectively induce chronic toxicity,neurological and developmental disorders,cardiovascular defects,and intestinal ailments in humans and aquatic species.Despite having a range of health and environmental consequences,this dark side of nano-photocatalysts has been comparatively less explored and discussed in the literature.In this review,the pros and cons of powder nanophotocatalysts are discussed in view of their advantages as well as disadvantages in wastewater treatment.The discussion encompasses their classification based on composition,dimensions,structure,and activity,as well as recent advancements in improving their photocatalytic efficiency.The article also explores the recent advances on their applications in photocatalytic removal of various water pollutants/contaminants of emerging concern(i.e.,organic pollutants,micro/nano plastics,heavy ions,disinfections,etc.)Furthermore,an emphasis on the role of such nano-photocatalysts as emerging(secondary)contaminants in water system,along with a thorough discussion of latest studies related to the health and environmental issues,has been discussed.Additionally,it addresses critical issues in applying powder nano-photocatalysts for wastewater detoxification and explores potential solutions to these challenges followed by future prospects.展开更多
The article is mainly about the advantages and disadvantages of information teaching in the case of a design of Container Transport.Information teaching did bring some good to the teaching,both to the teachers,and the...The article is mainly about the advantages and disadvantages of information teaching in the case of a design of Container Transport.Information teaching did bring some good to the teaching,both to the teachers,and the students and class.Yet it did have some side effects.And some suggestions are given to the information teaching to make it better used for teachers and students.展开更多
Autophagy plays an important role in the development and pathogenesis of various diseases. It can be induced by a variety of events such as hypoxia, nutrient-starvation, and mechanical damage. Many neurological disord...Autophagy plays an important role in the development and pathogenesis of various diseases. It can be induced by a variety of events such as hypoxia, nutrient-starvation, and mechanical damage. Many neurological disorders such Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis, Huntington’s disease, cerebral ischemia, and acute spinal cord injury (ASCI), are closely related to autophagy. However, therapeutic strategies to manipulate autophagy have not yet been fully deciphered due to the limited knowledge of the molecular mechanisms underlying autophagy in these disorders.展开更多
Chinese medicine (CM) has been an experience based practice over the past three thousand years. The safety and efficacy of CM has been practised through experience, rather than nowadays’ modern scientific measurement...Chinese medicine (CM) has been an experience based practice over the past three thousand years. The safety and efficacy of CM has been practised through experience, rather than nowadays’ modern scientific measurements. In this way, the development of CM has not been keeping pace with the advance in science and technology and the progress in orthodox medicine. In order to meet the requirements of modern science and technology, an evidence based approach must be adopted. Reassurance is needed to convince people for safety and efficacy of CM and give confidence to the evidence based demands ——“Tradition is confirmed by Modern Science” (1) .展开更多
Climate change strongly affected the structure and functions of natural ecosystems,e.g.the vegetation productivity decreased in the Northeast permafrost region due to the higher temperature and less precipitation,wher...Climate change strongly affected the structure and functions of natural ecosystems,e.g.the vegetation productivity decreased in the Northeast permafrost region due to the higher temperature and less precipitation,whereas in the Tibetan Plateau,the vegetation productivity increased,owing to the improved thermal resource.Climate change led to reduced precipitation in North and Northeast China and thus the reduced surface runoff.The public needs for energy were changed because of climate change,e.g.the shorter heating period in winter.Climate change profoundly influenced human health,pathophoresis and major projects by increasing extreme events,including frequency and magnitude,and causing more serious water shortage.Under the background of climate change,although the improved thermal resources can be helpful for extending the crop growth period,more extreme events may resulted in more instability in agricultural productivity.Not only did climate change indirectly affect the secondary and tertiary industries through the impacts on agriculture and natural resources,but also climate change mitigation measures,such as carbon tax,tariff and trading,had extensive and profound influences on the socioeconomic system.Further analysis indicated that the impact of climate change presented significant regional differences.The impact had its pros and cons,while the advantages outweighed the disadvantages.Based on the above analysis on the impacts of climate change,we put forward suggestions on coping with climate change.First,scientifically dealing with climate change will need to seek advantages while avoiding the disadvantages of climate change in order to achieve the orderly adaptation to climate change,which is characterized with"Overall best,long-term benefit."Second,quantitative adaptation should be given more attention,e.g.proposing operational schemes and predictable goals and using uncertainty analysis on adaptation measures.Third,more active coping strategy should be adopted to enhance China's future comprehensive competitiveness.The strategies include but are not limited to gradually adjusting the industrial structure,intensifying the research and development(R&D)of emission reduction technology and actively responding to the influence of carbon tax,tariff and trading on socioeconomic development in China.展开更多
The size of container vessels has grown up in the past ten years and the trend prospect to be continued, according to analysis almost half of current ships order is for vessels exceeding 12,000 TEU＇s. Mega vessels ha...The size of container vessels has grown up in the past ten years and the trend prospect to be continued, according to analysis almost half of current ships order is for vessels exceeding 12,000 TEU＇s. Mega vessels have advantages to liners and for holding down the coast of ocean shipping but also raising concerns among vessel operation, insurance and they require for infrastructure adaptations and productivity level. Moreover further increase in ship size could result negative impacts and crises in recession.展开更多
Green foods, also known as biologic foods or environmental protective foods, are healthy, quality and nutritional foods without pollutants or public hazard. There are four standards for producing green foods in China:...Green foods, also known as biologic foods or environmental protective foods, are healthy, quality and nutritional foods without pollutants or public hazard. There are four standards for producing green foods in China: 1. The origin of the products or the raw materials of products must conform with the ecological environment standards for the production of green foods. 2. Planting of farming crops, the raising of animals and poultry and the farming of aquatic products and展开更多
PRO Chen Wei University student Civil servants deserve job security and more career options.Many current civil servants are well-educated and hold master＇s or even doctorate degrees.If they are offered other career o...PRO Chen Wei University student Civil servants deserve job security and more career options.Many current civil servants are well-educated and hold master＇s or even doctorate degrees.If they are offered other career opportunities, they may achieve greater success.It is often the case that capable graduates working in civil service can＇t get promoted despite putting in years of hard work. These individuals are passed over for promotion not because they are incompetent or not dedicated to their jobs.展开更多
Ⅰ. GENERAL SITUATION The petrochemical industry is a technology and capital-intensive industry. The United States took the lead in the development of the petrochemical industry and started launching petrochemical pro...Ⅰ. GENERAL SITUATION The petrochemical industry is a technology and capital-intensive industry. The United States took the lead in the development of the petrochemical industry and started launching petrochemical projects in the 1930s and 1940s. The petrochemical industry in other developed countries, such as Germany, the United kingdom, France, Italy and Japan, began their development in the 1960s and 1970s.The petrochemical industry in these countries has played展开更多
The rise of scientific computing was one of the most important advances in the S&T progress during the second half of the 20th century. Parallel with theoretical exploration and scientific experiments,scientific c...The rise of scientific computing was one of the most important advances in the S&T progress during the second half of the 20th century. Parallel with theoretical exploration and scientific experiments,scientific computing has become the 'third means' for scientific activities in the world today. The article gives a panoramic review of the subject during the past 50 years in China and lists the contributions made by Chinese scientists in this field. In addition, it reveals some key contents of related projects in the national research plan and looks into the development vista for the subject in China at the dawning years of the new century.展开更多
In China the desire to be taller is high （excuse the pun）, despite people＇s genetic make-up. It＇s a desire driven by the sheer volume of folk competing for partners, promotions and prime job offerings, where any a...In China the desire to be taller is high （excuse the pun）, despite people＇s genetic make-up. It＇s a desire driven by the sheer volume of folk competing for partners, promotions and prime job offerings, where any advantage is sought in order to get a foot in the door. And with the vast numbers of job seekers competing for positions, recruiters behind those doors can afford to be picky. The word on the street is height means rapid advancement through the ranks. Many young professionals hold the common belief that taller people have more opportunity for promotion in the desperate climb up the corporate ladder.展开更多
文摘目的探究PROS1基因单核苷酸多态性(SNP)与包头地区汉族人群复发性流产(RSA)发生风险之间的相关性。方法选取RSA患者及对照人群各158例作为研究对象,测定蛋白S、蛋白C、抗凝血酶-Ⅲ活性;使用聚合酶链式反应-限制性片段长度多态性(PCR-RFLP)技术对PROS1基因rs13062355、rs6441600和rs12634349位点进行基因分型。采用非条件性Logistic回归分析PROS1基因三种SNP与RSA发生风险的相关性。结果RSA患者的蛋白S、抗凝血酶-Ⅲ活性下降(P<0.05);PROS1 SNP rs13062355在显性模型下与RSA发病风险相关:与携带TT基因型患者比较,携带CT+CC基因型的患者RSA发病风险下降(OR=0.398,95%CI:0.249~0.638)。SNP rs6441600、rs12634349与RSA的发病风险无关联。在PROS1 rs13062355、rs6441600、rs12634349构建的单体型中,单体型C-C-C在两组间差异有统计学意义(P<0.05);三阶交互模型rs13062355-rs6441600-rs12634349与RSA发病风险相关。结论PROS1 SNP rs13062355可能与包头地区汉族女性RSA患病风险相关;PROS1 rs13062355、rs6441600、rs12634349的单体型C-C-C降低了RSA发病风险;三阶模型rs13062355-rs6441600-rs12634349的交互作用在RSA的发生中具有协同效应。
基金Yunnan 046 Key Laboratory of Yi Dai Medicine and Yi Medicine(2024SS24046)。
文摘The current system of Chinese medicine education is centered on institutional education,teacher-training education,and continuing education,and it has realized the dynamic match between the supply of talents and the demand of the industry through large-scale cultivation,innovative teacher-training integration,and multi-dimensional continuing education.However,there are still problems such as the disconnection between the theory and practice of institutional education,the limited development of teacher-training education on a large scale,the uneven quality of continuing education,the conflict of combined education of traditional Chinese medicine and Western medicine,and the obstruction of internationalized education.This paper proposes to reconstruct the institutional curriculum system,innovate the stratified classification system of teacher training,strengthen the practice orientation of continuing education,promote the in-depth integration of Chinese and Western medicine,and improve the policy guarantee mechanism,and other improvement paths,aiming to build a new type of Chinese medicine personnel training system that emphasizes both classical inheritance and modern innovation,and the complementarity between institutional education and teacher training,so as to provide a decision-making reference for the sustainable development of Chinese medicine education.
基金Council of Scientific and Industrial Research(CSIR),New Delhi for providing Junior Research Fellowship(JRF),Ministry of Education(MoE)New Delhi and National Institute of Technology(NIT),Hamirpur for financial support.
文摘Photocatalysis is an advanced oxidation process where light exposure triggers a semiconducting nanomaterial(nano-photocatalyst)to generate electron-hole(e^(-)/h^(+))pairs and free radicals.This phenomenon is widely used for the photocatalysis-assisted removal of organic and other contaminants using wide range of nanophotocatalysts,offering an efficient approach to environmental remediation.However,the introduction of powdered nano-photocatalysts into water systems often leads to unintended secondary pollution in the form of residual nano-photocatalysts,ion leaching,free radicals,toxic by-products etc.Such practices potentially introduce emerging secondary contaminants into aquatic environments,posing risks to both aquatic life and human health.The resulting chemical by-products and intermediates can effectively induce chronic toxicity,neurological and developmental disorders,cardiovascular defects,and intestinal ailments in humans and aquatic species.Despite having a range of health and environmental consequences,this dark side of nano-photocatalysts has been comparatively less explored and discussed in the literature.In this review,the pros and cons of powder nanophotocatalysts are discussed in view of their advantages as well as disadvantages in wastewater treatment.The discussion encompasses their classification based on composition,dimensions,structure,and activity,as well as recent advancements in improving their photocatalytic efficiency.The article also explores the recent advances on their applications in photocatalytic removal of various water pollutants/contaminants of emerging concern(i.e.,organic pollutants,micro/nano plastics,heavy ions,disinfections,etc.)Furthermore,an emphasis on the role of such nano-photocatalysts as emerging(secondary)contaminants in water system,along with a thorough discussion of latest studies related to the health and environmental issues,has been discussed.Additionally,it addresses critical issues in applying powder nano-photocatalysts for wastewater detoxification and explores potential solutions to these challenges followed by future prospects.
文摘The article is mainly about the advantages and disadvantages of information teaching in the case of a design of Container Transport.Information teaching did bring some good to the teaching,both to the teachers,and the students and class.Yet it did have some side effects.And some suggestions are given to the information teaching to make it better used for teachers and students.
基金supported by the National Natural Science Foundation of China (81301047)
文摘Autophagy plays an important role in the development and pathogenesis of various diseases. It can be induced by a variety of events such as hypoxia, nutrient-starvation, and mechanical damage. Many neurological disorders such Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis, Huntington’s disease, cerebral ischemia, and acute spinal cord injury (ASCI), are closely related to autophagy. However, therapeutic strategies to manipulate autophagy have not yet been fully deciphered due to the limited knowledge of the molecular mechanisms underlying autophagy in these disorders.
文摘Chinese medicine (CM) has been an experience based practice over the past three thousand years. The safety and efficacy of CM has been practised through experience, rather than nowadays’ modern scientific measurements. In this way, the development of CM has not been keeping pace with the advance in science and technology and the progress in orthodox medicine. In order to meet the requirements of modern science and technology, an evidence based approach must be adopted. Reassurance is needed to convince people for safety and efficacy of CM and give confidence to the evidence based demands ——“Tradition is confirmed by Modern Science” (1) .
基金supported by National Science and Technology Support Program of China "Research on Assessment Technology of Impact and Risk of Climate Change in Key Fields and ItsApplication"[grant number 2012BAC19B00]National Key Scientific Research Project "Impact and Adaptive Strategy of Social and Economic System to Climate Change"[grant number2012CB955700]+1 种基金Strategic Priority Research Program of the Chinese Academy of Sciences "Environmental Pattern Change and Impact in Past One Hundred Years"[grant numberXDA05090307]"Impact of International Trade Policy and Emissions Reduction Policy to China"[Grant numberXDA05150200]
文摘Climate change strongly affected the structure and functions of natural ecosystems,e.g.the vegetation productivity decreased in the Northeast permafrost region due to the higher temperature and less precipitation,whereas in the Tibetan Plateau,the vegetation productivity increased,owing to the improved thermal resource.Climate change led to reduced precipitation in North and Northeast China and thus the reduced surface runoff.The public needs for energy were changed because of climate change,e.g.the shorter heating period in winter.Climate change profoundly influenced human health,pathophoresis and major projects by increasing extreme events,including frequency and magnitude,and causing more serious water shortage.Under the background of climate change,although the improved thermal resources can be helpful for extending the crop growth period,more extreme events may resulted in more instability in agricultural productivity.Not only did climate change indirectly affect the secondary and tertiary industries through the impacts on agriculture and natural resources,but also climate change mitigation measures,such as carbon tax,tariff and trading,had extensive and profound influences on the socioeconomic system.Further analysis indicated that the impact of climate change presented significant regional differences.The impact had its pros and cons,while the advantages outweighed the disadvantages.Based on the above analysis on the impacts of climate change,we put forward suggestions on coping with climate change.First,scientifically dealing with climate change will need to seek advantages while avoiding the disadvantages of climate change in order to achieve the orderly adaptation to climate change,which is characterized with"Overall best,long-term benefit."Second,quantitative adaptation should be given more attention,e.g.proposing operational schemes and predictable goals and using uncertainty analysis on adaptation measures.Third,more active coping strategy should be adopted to enhance China's future comprehensive competitiveness.The strategies include but are not limited to gradually adjusting the industrial structure,intensifying the research and development(R&D)of emission reduction technology and actively responding to the influence of carbon tax,tariff and trading on socioeconomic development in China.
文摘The size of container vessels has grown up in the past ten years and the trend prospect to be continued, according to analysis almost half of current ships order is for vessels exceeding 12,000 TEU＇s. Mega vessels have advantages to liners and for holding down the coast of ocean shipping but also raising concerns among vessel operation, insurance and they require for infrastructure adaptations and productivity level. Moreover further increase in ship size could result negative impacts and crises in recession.
文摘Green foods, also known as biologic foods or environmental protective foods, are healthy, quality and nutritional foods without pollutants or public hazard. There are four standards for producing green foods in China: 1. The origin of the products or the raw materials of products must conform with the ecological environment standards for the production of green foods. 2. Planting of farming crops, the raising of animals and poultry and the farming of aquatic products and
文摘PRO Chen Wei University student Civil servants deserve job security and more career options.Many current civil servants are well-educated and hold master＇s or even doctorate degrees.If they are offered other career opportunities, they may achieve greater success.It is often the case that capable graduates working in civil service can＇t get promoted despite putting in years of hard work. These individuals are passed over for promotion not because they are incompetent or not dedicated to their jobs.
文摘Ⅰ. GENERAL SITUATION The petrochemical industry is a technology and capital-intensive industry. The United States took the lead in the development of the petrochemical industry and started launching petrochemical projects in the 1930s and 1940s. The petrochemical industry in other developed countries, such as Germany, the United kingdom, France, Italy and Japan, began their development in the 1960s and 1970s.The petrochemical industry in these countries has played
文摘The rise of scientific computing was one of the most important advances in the S&T progress during the second half of the 20th century. Parallel with theoretical exploration and scientific experiments,scientific computing has become the 'third means' for scientific activities in the world today. The article gives a panoramic review of the subject during the past 50 years in China and lists the contributions made by Chinese scientists in this field. In addition, it reveals some key contents of related projects in the national research plan and looks into the development vista for the subject in China at the dawning years of the new century.
文摘In China the desire to be taller is high （excuse the pun）, despite people＇s genetic make-up. It＇s a desire driven by the sheer volume of folk competing for partners, promotions and prime job offerings, where any advantage is sought in order to get a foot in the door. And with the vast numbers of job seekers competing for positions, recruiters behind those doors can afford to be picky. The word on the street is height means rapid advancement through the ranks. Many young professionals hold the common belief that taller people have more opportunity for promotion in the desperate climb up the corporate ladder.
