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Meet the Expert
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《Asian Journal of Andrology》 2025年第4期F0002-F0002,共1页
ECharles Osterberg。Dr.Osterberg is a board-certified urologist with fellowship training in male genitourinary reconstruction.He moved to Austin(TX,USA)in 2016 to join the University of Texas-Dell Medical School as As... ECharles Osterberg。Dr.Osterberg is a board-certified urologist with fellowship training in male genitourinary reconstruction.He moved to Austin(TX,USA)in 2016 to join the University of Texas-Dell Medical School as Associate Professor of Surgery.Dr.Osterberg specializes in reconstructive urology,genitourinary trauma,prosthetics,and robotic surgery.After serving as the Chief of Urology at Dell-Seton Medical Center-the main teaching hospital for Dell Medical School for 7 years,Dr.Osterberg transitioned his practice to Urology Austin,an affiliate of Urology America.At his new practice,he and his team have performed hundreds of complex urologic reconstructions and urethral stricture surgeries. 展开更多
关键词 male genitourinary reconstructionhe reconstructive urologygenitourinary traumaprostheticsand UROLOGY genitourinary trauma prosthetics reconstructive urology robotic surgery urethral stricture surgeries
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A machine learning-assisted multifunctional tactile sensor for smart prosthetics 被引量:3
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作者 Yue Li Lin Yang +7 位作者 Shihao Deng Hong Huang Yingyi Wang Zuoping Xiong Simin Feng Shuqi Wang Tie Li Ting Zhang 《InfoMat》 SCIE CSCD 2023年第9期78-89,共12页
The absence of tactile perception limits the dexterity of a prosthetic hand and its acceptance by amputees.Recreating the sensing properties of the skin using a flexible tactile sensor could have profound implications... The absence of tactile perception limits the dexterity of a prosthetic hand and its acceptance by amputees.Recreating the sensing properties of the skin using a flexible tactile sensor could have profound implications for prosthetics,whereas existing tactile sensors often have limited functionality with cross-interference.In this study,we propose a machine-learning-assisted multifunctional tactile sensor for smart prosthetics,providing a human-like tactile sensing approach for amputations.This flexible sensor is based on a poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate)(PEDOT:PSS)-melamine sponge,which enables the detection of force and temperature with low cross-coupling owing to two separate sensing mechanisms:the open-circuit voltage of the sensor as a force-insensitive intrinsic variable to measure the absolute temperature and the resistance as a temperature-insensitive extrinsic variable to measure force.Furthermore,by analyzing the unsteady heat conduction and characterizing it using real-time thermal imaging,we demonstrated that the process of open-circuit voltage variation resulting from the unsteady heat conduction is closely correlated with the heatconducting capabilities of materials,which can be utilized to discriminate between substances.Assisted by the decision tree algorithm,the device is endowed with thermal conductivity sensing ability,which allows it to identify 10 types of substances with an accuracy of 94.7%.Furthermore,an individual wearing an advanced myoelectric prosthesis equipped with the above sensor can sense pressure,temperature,and recognize different materials.We demonstrated that our multifunctional tactile sensor provides a new strategy to help amputees feel force,temperature and identify the material of objects without the aid of vision. 展开更多
关键词 machine learning material classification multifunctional tactile sensor smart prosthetics unsteady heat conduction
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Introspective Study of Trans-Tibias Amputees in View of the Design of a Durable Prosthetic Foot
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作者 Boukar Abdelhakim Mahamat Maintah Ardjoune Debsi Edjibey 《Open Journal of Applied Sciences》 2025年第1期259-273,共15页
The prosthesis is an artificial device that can replace an organ of a human body member to restore a compromised function. It is necessary following the removal of a human organ, which can occur as a result of an illn... The prosthesis is an artificial device that can replace an organ of a human body member to restore a compromised function. It is necessary following the removal of a human organ, which can occur as a result of an illness, trauma or congenital malformation. The trans-tibia prosthesis, in particular, allows the amputee patient to recover the impaired function and regain autonomy, while facilitating their daily social integration. The trans-tibia prosthesis consists of a socket, a sleeve, connecting elements and a prosthetic foot. Each of these components plays a very important role. Among these components, the prosthetic foot usually called “SACH foot” is very often replaced due to cracking and therefore has a fairly short lifespan. At the Center for Equipment and Rehabilitation of Kabalaye (CERK), the SACH foot made using polyurethane and wood is imported and is given to patients with reduced mobility. The aim of this article is twofold, on the one hand, to make a social and pathological study of trans-tibia amputees in relation to the use of the SACH foot prosthesis, on the other hand, to compare this foot with a new prosthetic foot proposed and which is manufactured using extruded polystyrene. The result of prosthetic tests carried out on twenty-four amputees showed that the foot manufactured using extruded polystyrene is better in terms of resistance, bulk and adaptability to active amputees. 展开更多
关键词 Prosthesis Prosthetic Foot Trans-Tibia Amputee SACH Foot
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Advances in Pediatric Heart Valve Replacement:A State-of-the-Art Review
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作者 Baker M.Ayyash Yen Chuan Chen +1 位作者 Ahmad Sallehuddin Ziyad M.Hijazi 《Congenital Heart Disease》 2025年第2期143-179,共37页
Pediatric heart valve replacement(PHVR)remains a challenging procedure due to the uniqueanatomical and physiological characteristics of children,including growth and development,as well asthe long-term need for durabl... Pediatric heart valve replacement(PHVR)remains a challenging procedure due to the uniqueanatomical and physiological characteristics of children,including growth and development,as well asthe long-term need for durable valve function.This review provides an overview of both surgical andtranscatheter options for aortic,mitral,pulmonary,and tricuspid valve replacements in pediatric patients,highlighting the indications,outcomes,and advancements in technology and technique.Surgical valvereplacement traditionally involves the implantation of biological or mechanical prosthetic valves,withbiologicalvalves beingpreferred in children to reduce the need for lifelong anticoagulation therapy.However,the limitation ofbiological prostheses,nanely their inability to grow with the child,necessitates the frequentneed for reoperations.Recent innovations in valve engineering,such as the development of tissue engineeredand expandable valves,aim to address these issues.Transcatheter valve replacement(TVR)has emergedas a promising alternative,particularly for patients with complex anatomy or those who are high-risk fortraditional surgery.While the use of transcatheter devices in children remains limited due to the smallervascular size and limited long-termn data,several studies have demonstrated the feasibility and safety ofthe procedure in certain patient populations.Despite these advancements,challenges related to valvesize,durability,and the need for individualized treatment planning persist.The future of pediatric heartvalve replacemnent will likely involve a multidisciplinary approach combining surgical,transcatheter,andregenerative medicine strategies,aimed at optimizing outcomes,reducing the need for reinterventions,andimproving long-term quality of life for pediatric patients with valvularheart disease.This article discussesall options availab le for patients with valvular dysfunction,making it easy for parents/patients to go to as areference source of information. 展开更多
关键词 Pediatric heart valve replacement transcathetervalve replacement surgicalvalve replacement prosthetic valves biological valves mechanical valves valve durability tissue-engineered valves eocpandable valves Individualized approaches
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Combined anterior corneal elastic sublaminectomy,conjunctival flap,and prosthetic eyepiece for ocular atrophy following foldable capsular vitreous body implantation in severe trauma
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作者 Ling-Dan Wu Pei-Jie Huang +7 位作者 Zhou Peng Huang Zhang Sheng-Xiang Zhang An-An Wang Meng-Tian Qiu Li-Chang Ma Ye-Feng Zhu Qi-Hua Xu 《International Journal of Ophthalmology(English edition)》 2025年第11期2149-2154,共6页
AIM:To investigate the outcome of combined anterior corneal elastic sublaminectomy,conjunctival flap,and prosthetic eyepiece for ocular atrophy following foldable capsular vitreous body(FCVB)implantation in severe tra... AIM:To investigate the outcome of combined anterior corneal elastic sublaminectomy,conjunctival flap,and prosthetic eyepiece for ocular atrophy following foldable capsular vitreous body(FCVB)implantation in severe trauma.METHODS:This study conducted a retrospective analysis of 38 patients who underwent conjunctival flap coverage followed by prosthetic eyepiece fitting after developing ocular atrophy secondary to FCVB surgery.Anterior corneal elastic sublaminectomy combined with conjunctival coverage was performed on the FCVBimplanted atrophic eyes.Prosthetic lenses were fitted after complete healing of the stroma and conjunctiva and suture removal.Corneal irritation,eyeball protrusion,axial length,lid height,cosmetic satisfaction,and pain numerical rating scale scores were observed before the conjunctival flap covering and after the prosthetic eyepiece surgery.RESULTS:The ocular protrusion was 11 mm preoperatively and 14 mm postoperatively,with the difference being statistically significant(Z=-5.459,P<0.001).The ocular axis length was 20.82±0.94 mm in the experimental group and 23.57±0.33 mm in the control group,showing a statistically significant difference(t=-20.207,P<0.05).The lid height was 6 mm in the experimental group and 9 mm in the control group,a difference that was statistically significant(Z=-5.326,P<0.001).The appearance satisfaction score was 1 in the experimental group and 4 in the control group,with this difference being statistically significant(Z=-5.447,P=0.001).Regarding the pain numerical rating scale score,the ranges were 0-2 in the experimental group and 0 in the control group.No discomfort was reported after wearing the prosthetic eyepiece,and the difference was not statistically significant(Z=-1.100,P>0.05).There was no statistically significant difference between pre-and post-treatment satisfaction.CONCLUSION:A conjunctival flap covering and a prosthetic eyepiece after FCVB postoperative atrophy can reduce the number of surgeries,alleviate patients’economic burdens,satisfy patients’psychological eyeball retention requirements,and provide better cosmetic efficacies for patients desiring eyeball retention or silicone-oil dependence. 展开更多
关键词 open ocular trauma conjunctival flap prosthetic eyepiece foldable capsular vitreous body
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A Finite Element Approach to Enhance the Performance of Nano⁃Reinforced Prosthetic Foot
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作者 Akankshya Priyadarshini Mihir Kumar Sutar Sarojrani Pattnaik 《Journal of Harbin Institute of Technology(New Series)》 2025年第3期23-30,共8页
Functionally Graded Materials(FGMs)are innovative advanced quality materials in the field of composites concerning their strength,mechanical,and thermal properties.Nowadays,the modern requirement of the industry in th... Functionally Graded Materials(FGMs)are innovative advanced quality materials in the field of composites concerning their strength,mechanical,and thermal properties.Nowadays,the modern requirement of the industry in the fields of health care,aerospace,and power sectors needs the rapid evolution of new components,which allows researchers to invent new materials to satisfy the functional requirements of modern technology.Tissue engineering is one of the most concerned areas of the application of FGM in the healthcare sector,where the tailored properties of FGM play a significant role in building and growing an artificial structure that heals the damaged tissue of the body parts and meets the desired application that the part needs to perform.This paper highlights the suitability of the combination of a nano⁃structure enhanced epoxy functionally graded material,its properties,and applicability in the design of a prosthetic foot where it provides the mobility and comfort of the body part like natural tissue.The analytical study is done by designing an ANSYS model and simulating the results of equivalent stress and directional deformation.The Finite Element(FE)approach is used to optimize the output results of stress⁃strain analysis,different weight percentages of nano⁃filler are taken for performance enhancement.A comparative analysis is done with the previously established results taking carbon fiber⁃reinforced composites that offer a successful validation of the present results obtained.Furthermore,this study also provides a clear understanding of the justification of the composition considered for the effective application in the field of prosthetics field. 展开更多
关键词 Functionally Graded Material(FGM) Finite element(FE) prosthetic foot ANSYS model
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Thrombolysis in dysfunctional valve and stroke
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作者 Dormar David Barrios-Martínez Yuri Valentina Pinzon +1 位作者 Veronica Giraldo Gina Gonzalez 《World Journal of Critical Care Medicine》 2025年第2期178-184,共7页
BACKGROUND Valvular heart disease affects more than 100 million people worldwide and is associated with significant morbidity and mortality.The prevalence of at least moderate valvular heart disease is 2.5%across all ... BACKGROUND Valvular heart disease affects more than 100 million people worldwide and is associated with significant morbidity and mortality.The prevalence of at least moderate valvular heart disease is 2.5%across all age groups,but its prevalence increases with age.Mitral regurgitation and aortic stenosis are the most frequent types of valvular heart disease in the community and hospital context,res-pectively.Surgical valve replacement(or mitral valve repair)is the standard of care for treating heart valve disease.However,the replacement of a prosthetic heart valve can lead to complications,either in the peri-procedural phase or in the long-term follow-up period.CASE SUMMARY We present a case of a 71-year-old female patient with a history of mitral valve replacement and warfarin anti-coagulation therapy.She was admitted to the intensive care unit due to spontaneously reperfused ischemic stroke of probable cardioembolic etiology.A dysfunctional mitral prosthesis was identified due to malfunction of one of the fixed discs.Furthermore,a possible microthrombotic lesion was suspected.Therefore,systemic thrombolysis was performed with subsequent normalization of mitral disc opening and closing.CONCLUSION This case underscores the critical importance of a multidisciplinary approach for timely decision-making in critically ill patients with prosthetic valve complications. 展开更多
关键词 Mitral valve thrombolysis STROKE Recombinant human plasminogen tissue activator Heart valve disease Prosthetic valve-associated thrombosis Thrombotic dysfunction
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Digit amputation prosthetics
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作者 Travis J.Miller 《Plastic and Aesthetic Research》 2023年第1期229-235,共7页
Digit amputations are the most common amputation worldwide.This manuscript describes the impairments imposed by digit loss and the potential benefits of digit prosthetics.This review of the literature is designed to p... Digit amputations are the most common amputation worldwide.This manuscript describes the impairments imposed by digit loss and the potential benefits of digit prosthetics.This review of the literature is designed to provide a reference for healthcare workers and patients for identifying and selecting prosthetic options for digit amputees. 展开更多
关键词 Hand surgery AMPUTATION prosthetics OUTCOMES plastic surgery orthopedic surgery hand reconstruction
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Assistive Devices and Clothing: Exploring Adaptive Clothing Needs for Women with Lower Limb Prostheses Using the FEA Model 被引量:1
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作者 Mastourah Al Asmari Mirahan Farag Zedan 《Open Journal of Applied Sciences》 2024年第10期2901-2922,共22页
This study aimed to comprehensively investigate the essential considerations in designing adaptive clothing for women with lower limb prostheses in Saudi Arabia. Employing a qualitative methodology, the research entai... This study aimed to comprehensively investigate the essential considerations in designing adaptive clothing for women with lower limb prostheses in Saudi Arabia. Employing a qualitative methodology, the research entailed semi-structured, in-depth interviews with women utilizing lower limb prostheses and prosthetic specialists. This approach was selected to unearth pivotal design prerequisites and comprehend the specific challenges these women encounter within the realm of clothing. The utilization of selective sampling facilitated the collection of intricate and valuable insights. A Functional, Expressive, and Aesthetic (FEA) User Needs model was utilized to scrutinize participant feedback. Functional requisites encompass ease of dressing and undressing, accessibility to the prosthetic limb, comfort, mobility with the prosthesis, and appropriate fit. Additionally, participants highlighted various expressive needs, including privacy preservation, modesty, camouflaging disability appearances, maintaining alignment with non-disabled women’s fashion, and considerations about the aesthetic aspects of garments. 展开更多
关键词 Assistive Devices Adaptive Clothing Lower Limb prosthetics Functional Expressive and Aesthetic (FEA) Model
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A Novel Locomotion Rule Rmbedding Long Short-Term Memory Network with Attention for Human Locomotor Intent Classification Using Multi-Sensors Signals
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作者 Jiajie Shen Yan Wang Dongxu Zhang 《Computers, Materials & Continua》 SCIE EI 2024年第6期4349-4370,共22页
Locomotor intent classification has become a research hotspot due to its importance to the development of assistive robotics and wearable devices.Previous work have achieved impressive performance in classifying stead... Locomotor intent classification has become a research hotspot due to its importance to the development of assistive robotics and wearable devices.Previous work have achieved impressive performance in classifying steady locomotion states.However,it remains challenging for these methods to attain high accuracy when facing transitions between steady locomotion states.Due to the similarities between the information of the transitions and their adjacent steady states.Furthermore,most of these methods rely solely on data and overlook the objective laws between physical activities,resulting in lower accuracy,particularly when encountering complex locomotion modes such as transitions.To address the existing deficiencies,we propose the locomotion rule embedding long short-term memory(LSTM)network with Attention(LREAL)for human locomotor intent classification,with a particular focus on transitions,using data from fewer sensors(two inertial measurement units and four goniometers).The LREAL network consists of two levels:One responsible for distinguishing between steady states and transitions,and the other for the accurate identification of locomotor intent.Each classifier in these levels is composed of multiple-LSTM layers and an attention mechanism.To introduce real-world motion rules and apply constraints to the network,a prior knowledge was added to the network via a rule-modulating block.The method was tested on the ENABL3S dataset,which contains continuous locomotion date for seven steady and twelve transitions states.Experimental results showed that the LREAL network could recognize locomotor intents with an average accuracy of 99.03%and 96.52%for the steady and transitions states,respectively.It is worth noting that the LREAL network accuracy for transition-state recognition improved by 0.18%compared to other state-of-the-art network,while using data from fewer sensors. 展开更多
关键词 Lower-limb prosthetics deep neural networks motion classification
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Prospects of 3D Printing Technology in Dental Medicine
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作者 Ye Sun 《Journal of Clinical and Nursing Research》 2024年第6期398-403,共6页
With the continuous advancement of technology,the application of 3D printing technology in the field of dental medicine is becoming increasingly widespread.This article aims to explore the current applications and fut... With the continuous advancement of technology,the application of 3D printing technology in the field of dental medicine is becoming increasingly widespread.This article aims to explore the current applications and future potential of 3D printing technology in dental medicine and to analyze its benefits and challenges.It first introduces the current state of 3D printing technology in dental implants,crowns,bridges,orthodontics,and maxillofacial surgery.It then discusses the potential applications of 3D printing technology in oral tissue engineering,drug delivery systems,personalized dental prosthetics,and surgical planning.Finally,it analyzes the benefits of 3D printing technology in dental medicine,such as improving treatment accuracy and patient comfort,and shortening treatment times,while also highlighting the challenges faced,such as costs,material choices,and technical limitations.This article aims to provide a reference for professionals in the field of dental medicine and to promote the further application and development of 3D printing technology in this area. 展开更多
关键词 3D printing technology Dental medicine Dental implants CROWNS Bridges ORTHODONTICS Maxillofacial surgery Tissue engineering Drug delivery systems Personalized dental prosthetics Surgical planning
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Design,Simulation and Kinematic Validation of a Hip Prosthetic Mechanism with a Multimotor Function
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作者 Majun Song Zhongyi Li +4 位作者 Jingjing Jiang Weihai Chen Sheng Guo Hao Zheng Lianzheng Niu 《Journal of Bionic Engineering》 SCIE EI CSCD 2024年第3期1321-1333,共13页
We previously developed a powered hip prosthetic mechanism with kinematic functions of hip flexion-extension and abduction-adduction,and its theoretical and simulation-based kinematics were verified.Because internal-e... We previously developed a powered hip prosthetic mechanism with kinematic functions of hip flexion-extension and abduction-adduction,and its theoretical and simulation-based kinematics were verified.Because internal-external hip rotation has a positive effect on the movements of human lower limbs according to medical research,we developed a novel hip prosthetic mechanism based on a previous hip prosthesis that possesses motion characteristics similar to those of a human bionic hip,and the motion characteristics of multiple Degrees-of-Freedom(DoFs)were analyzed after kinematic modeling.Then,a walking model of the human‒machine model was established,and the walking stability of an amputee,which reflects the rehabilitation effect,was explored while the hip prosthetic mechanism considered the internal-external rotation of the hip.Finally,a prototype and its verification platform were built,and kinematic validation of the hip prosthetic mechanism was carried out.The results showed that the designed Parallel Mechanism(PM)possesses human-like motion characteristics similar to those of a human bionic hip and can be used as a hip prosthesis.Moreover,the existing motion characteristic of internal-external hip rotation can enhance the walking stability of an amputee via this hip prosthetic mechanism. 展开更多
关键词 Hip prosthetic mechanism Parallel mechanism Walking stability Kinematic validation
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Native and prosthetic septic arthritis in a university hospital in Saudi Arabia:A retrospective study
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作者 Reham Kaki 《World Journal of Orthopedics》 2024年第8期722-733,共12页
BACKGROUND Septic arthritis,whether native or prosthetic,poses a significant challenge in clinical practice due to its potentially devastating consequences.Despite its clinical importance,there remains a dearth of com... BACKGROUND Septic arthritis,whether native or prosthetic,poses a significant challenge in clinical practice due to its potentially devastating consequences.Despite its clinical importance,there remains a dearth of comprehensive studies and standardized diagnostic criteria,particularly in the Kingdom of Saudi Arabia.AIM To investigate the epidemiology,microbiological profiles,and clinical characteristics of native and prosthetic septic joints in the Saudi Arabian population.METHODS Medical records of patients diagnosed with septic arthritis between January 1,2015,and December 31,2022,were retrospectively reviewed.Data regarding patient demographics,clinical presentation,microbiological cultures,treatment modalities,and outcomes were analyzed.RESULTS In a retrospective review of 52 cases of septic arthritis,a balanced gender distribution was observed(1:1 ratio),with the knee being the most commonly affected joint(80.8%).Methicillin-resistant Staphylococcus aureus predominated in native joints(24.2%),while Brucella spp.was more prevalent in prosthetic joints(21.1%).Joint preservation was achieved in most cases(84.6%),with no significant difference in clinical features between native and prosthetic joints.However,certain comorbidities were more common in native joint cases,including renal impairment(P=0.002),hemodialysis(P=0.004),heart disease(P=0.013),and chronic liver disease(P=0.048).At the same time,osteoarthritis was more prevalent in prosthetic joint cases(P=0.013).Vancomycin was the most frequently used antibiotic(26.9%),and most patients received antibiotics before joint aspiration(57.7%).Surgical intervention,predominantly arthrotomy,was required in most cases(32.7%).Notably,a significant association was found between joint type and mortality(odds ratio=0.587,P=0.048),as well as the Charlson comorbidity index and mortality(P=0.001).CONCLUSION This study highlighted distinctive microbiological profiles and etiological factors in septic arthritis cases in the Saudi Arabian population. 展开更多
关键词 Septic arthritis Native joint Prosthetic joint EPIDEMIOLOGY Diagnostic criteria Saudi Arabia
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Mid-term outcomes of a kinematically designed cruciate retaining total knee arthroplasty
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作者 Jonathan L Katzman Akram A Habibi +4 位作者 Muhammad A Haider Casey Cardillo Ivan Fernandez-Madrid Morteza Meftah Ran Schwarzkopf 《World Journal of Orthopedics》 2024年第2期118-128,共11页
BACKGROUND Advances in implant material and design have allowed for improvements in total knee arthroplasty(TKA)outcomes.A cruciate retaining(CR)TKA provides the least constraint of TKA designs by preserving the nativ... BACKGROUND Advances in implant material and design have allowed for improvements in total knee arthroplasty(TKA)outcomes.A cruciate retaining(CR)TKA provides the least constraint of TKA designs by preserving the native posterior cruciate ligament.Limited research exists that has examined clinical outcomes or patient reported outcome measures(PROMs)of a large cohort of patients undergoing a CR TKA utilizing a kinematically designed implant.It was hypothesized that the studied CR Knee System would demonstrate favorable outcomes and a clinically significant improvement in pain and functional scores.AIM To assess both short-term and mid-term clinical outcomes and PROMs of a novel CR TKA design.METHODS A retrospective,multi-surgeon study identified 255 knees undergoing a TKA utilizing a kinematically designed CR Knee System(JOURNEY™II CR;Smith and Nephew,Inc.,Memphis,TN)at an urban,academic medical institution between March 2015 and July 2021 with a minimum of two-years of clinical follow-up with an orthopedic surgeon.Patient demographics,surgical information,clinical outcomes,and PROMs data were collected via query of electronic medical records.The PROMs collected in the present study included the Knee Injury and Osteoarthritis Outcome Score for Joint Replacement(KOOS JR)and Patient-Reported Outcomes Measurement Information System(PROMIS■)scores.The significance of improvements in mean PROM scores from preoperative scores to scores collected at six months and two-years postoperatively was analyzed using Independent Samples t-tests.RESULTS Of the 255 patients,65.5%were female,43.8%were White,and patients had an average age of 60.6 years.Primary osteoarthritis(96.9%)was the most common primary diagnosis.The mean surgical time was 105.3 minutes and mean length of stay was 2.1 d with most patients discharged home(92.5%).There were 18 emergency department(ED)visits within 90 d of surgery resulting in a 90 d ED visit rate of 7.1%,including a 2.4%orthopedic-related ED visit rate and a 4.7%non-orthopedic-related ED visit rate.There were three(1.2%)hospital readmissions within 90 d postoperatively.With a mean time to latest follow-up of 3.3 years,four patients(1.6%)required revision,two for arthrofibrosis,one for aseptic femoral loosening,and one for peri-prosthetic joint infection.There were significant improvements in KOOS JR,PROMIS Pain Intensity,PROMIS Pain Interference,PROMIS Mobility,and PROMIS Physical Health from preoperative scores to six month and two-year postoperative scores.CONCLUSION The evaluated implant is an effective,novel design offering excellent outcomes and low complication rates.At a mean follow up of 3.3 years,four patients required revisions,three aseptic and one septic,resulting in an overall implant survival rate of 98.4%and an aseptic survival rate of 98.8%.The results of our study demonstrate the utility of this kinematically designed implant in the setting of primary TKA. 展开更多
关键词 Total knee arthroplasty Cruciate retaining Kinematic design SURVIVORSHIP Bearing material Prosthetic design Clinical outcomes Patient-reported outcome measures
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Early Prosthetic Valve Endocarditis with Mycobacterium Tuberculosis after Mitral Valve Replacement: A Case Report
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作者 Papa Amath Diagne Mory Camara +12 位作者 Papa Ousmane Ba Momar Sokhna Diop Moussa Samba Abdou Lahad Mbengue Jean Claude Ndiogou Dione Myriam Bizrane Marième Soda Mbaye Moussa Seck Diop Toudiani Malam Kaka Papa Salmane Ba Papa Adama Dieng Amadou Gabriel Ciss Assane Ndiaye 《World Journal of Cardiovascular Surgery》 2024年第3期33-40,共8页
Background: Tuberculous endocarditis is a rare but serious complication of heart valve replacement surgery. We report the case of a 24-year-old patient, who presented with tuberculous endocarditis after mechanical mit... Background: Tuberculous endocarditis is a rare but serious complication of heart valve replacement surgery. We report the case of a 24-year-old patient, who presented with tuberculous endocarditis after mechanical mitral valve replacement, with a favorable clinical course following anti-tuberculosis treatment. Case Presentation: We report a 24-year-old male patient, admitted to the cardiac surgery department of the Fann Hospital (Dakar, Senegal), for the management of severe mixed (rheumatic and endocarditic) mitral insufficiency with associated tricuspid insufficiency. He had a history of recurrent angina and polyarthralgia in childhood, was hospitalized several times for refractory global cardiac decompensation, and for a suspected infective endocarditis a month before his admission. On admission, the clinical examination revealed signs suggestive of mitral and tricuspid insufficiency. Transthoracic echocardiography revealed severe post-endocarditic mitral insufficiency with A3 amputation, highly mobile 15 mm vegetations on the free edge of the large valve, moderate tricuspid insufficiency, and severe pulmonary artery hypertension. Mechanical mitral valve replacement and tricuspid valve annuloplasty using autologous pericardial strip were performed via median sternotomy. After ten days, the patient presented with global cardiac decompensation associated with a clinico-biological infectious syndrome, and tans-oesophageal echography revealed an abscess at the sinotubular junction, communicating with the aorta. A thoraco-abdomino-pelvic CT scan was done, which revealed a bilateral alveolar-interstitial syndrome with mediastinal lymphadenopathy. Anti-tuberculosis treatment with RHZE was initiated for 06 months. The clinical course was favorable. Conclusion: Tuberculous endocarditis in prostheses is a serious complication of heart valve replacement surgery, which may evolve favorably under medical treatment. 展开更多
关键词 Tuberculous Endocarditis Prosthetic Valve Endocarditis Mycobacterium Tuberculosis
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Effectiveness of Oral Care in Implant Denture Restoration in Chronic Periodontitis
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作者 Jianli Zheng 《Journal of Clinical and Nursing Research》 2024年第6期214-219,共6页
Objective:To explore the effect of observation of oral care in implant denture restoration of chronic periodontitis.Methods:80 patients with chronic periodontitis implant denture restoration admitted from March 2022 t... Objective:To explore the effect of observation of oral care in implant denture restoration of chronic periodontitis.Methods:80 patients with chronic periodontitis implant denture restoration admitted from March 2022 to March 2023 in the hospital were selected.They were randomly divided into an observation group and a control group,with 40 cases in each group.Both groups of patients received routine treatment and care.The patients in the control group used routine oral care methods to carry out oral care,the patients in the observation group carried out oral care on the basis of the control group,observation and analysis of the patients'mastery of oral knowledge,as well as the depth of the probing and the level of clinical attachment.Results:The oral knowledge mastery of the observation group was 72.31±6.98 after the nursing intervention,which was significantly higher than the score of 86.12±7.36 of the patients in the control group who used conventional oral care,and the difference was statistically significant at P<0.05;the depth of probing and the clinical attachment level of the observation group were 2.43±0.58 and 4.31±0.86 respectively,which were significantly better than those of the control group.The depth of probing and clinical attachment level scores of the observation group were 2.99±0.54 and 5.36±1.02 respectively,and P<0.05 was considered statistically significant.Conclusion:The combination of conventional treatment and oral care can effectively improve the treatment effect of implant denture prosthesis for chronic periodontitis.However,it is necessary to pay attention to the psychological counseling of the patients in the specific clinical application to ensure that the patients can actively cooperate with the clinical treatment. 展开更多
关键词 Oral care Chronic periodontitis Prosthetic restoration
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Silver micro- and nanoparticles filled silicone for limb prosthetics
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作者 Sofiya Eksharova Yuliya Poletaeva +3 位作者 Anna Kurenkova Denis Mishchenko Egor Aydakov Vladimir Serdyukov 《Biomaterials Translational》 2025年第2期202-211,共10页
The threat of bacterial growth on the skin under the prosthetic liners or sleeves is an important problem,which can cause various serious diseases up to the repeated amputation.One of the promising ways to solve this ... The threat of bacterial growth on the skin under the prosthetic liners or sleeves is an important problem,which can cause various serious diseases up to the repeated amputation.One of the promising ways to solve this problem is to use antibacterial materials as a liner/sleeve material.Among others composite based on the silicone polymer with silver particles additive is may be a simple and effective solution,since the silicone is the main material for the prosthetic liners and sleeves and silver demonstrates pronounced antibacterial effect.However,the questions related to the optimal concentration of silver in silicone that results in maximum antibacterial efficiency without harming human skin are still open.In the present work,synthesis of metallic silver powder from a mixture of micro-and nanoparticles was performed and composite samples based on silicone polymer with different silver concentrations were fabricated.The antibacterial properties of fabricated samples were studied using the microdilution method against gram-positive spore-forming bacteria Bacillus subtilis.The cytotoxic effect of the tested samples was evaluated on healthy human fibroblast cell(NAF1nor).Moreover,the effect of adding silver micro-and nanoparticles to silicone on its extensibility and hardness was studied.The results showed that the addition of silver has a noticeable effect on the antibacterial properties of silicone polymer reaching more than 50%.Furthermore,all tested silicone-silver composites were shown to be non-toxic.The presence of silver does not significantly affect the relative elongation of the samples.However,hardness increases with higher silver concentrations.In the final phase,prototypes of the silver-filled silicone prosthetic sleeve were fabricated for utilisation by the patient at the prosthetic-orthopaedic clinic.The testing of the prototype was successfully completed by the patient,thereby demonstrating practical functionality and suitability for clinical use. 展开更多
关键词 Antibacterial materials Limb prosthetics Medical materials Nanomaterials Silicone Silver
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Conceptual exploration of a gravity-assisted electrorheological fluid-based gripping methodology for assistive technology
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作者 Ivo Radice Jeroen H.M.Bergmann 《Bio-Design and Manufacturing》 SCIE CSCD 2019年第3期145-152,共8页
Gripping devices help patients carry out everyday tasks and increase their independence.However,there seems to be a lack of bionic gripping technologies that can fully adapt to any possible shape,as the use of artific... Gripping devices help patients carry out everyday tasks and increase their independence.However,there seems to be a lack of bionic gripping technologies that can fully adapt to any possible shape,as the use of artificial fingers and predetermined grip settings limits the operating space.The development of a more agile device,which is operated by a simple control paradigm,could greatly benefit users.An electrorheological(ER)fluid system should be able to adapt to the shape of an object and then hold that configuration.The aim of this study was to explore if a conceptual prototype of an ER system could hold a geometric shape when it is activated.A test rig was constructed with a moving part(set in different silicone oils)that could be displaced using a tensometer.Silica particles were dispersed in the silicone oils,and a field with a voltage of 4 kV mm?1 was generated to activate the fluid.The results show that the developed system can support an increased force when activated and hold a simple geometric position without any noticeable delay.This outcome provides an initial proof of concept for a possible new(gravity-assisted)gripping approach using smart fluids,which could be developed with materials that are biocompatible and widely available. 展开更多
关键词 Smart materials prosthetics EXOSKELETON GRASPING Manipulation Assistive technologies
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人工瓣心内膜炎
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作者 李广仁 《中日友好医院学报》 1989年第4期241-243,共3页
人工瓣心内膜炎(prosthetic valve endocanditis,PVE)是瓣膜移植术后很危险的并发症,尽管应用预防性抗菌素和改进了手术技术使这一并发症明显减少,但很多“心血管中心”报告仍有2%~4%的发生率。习惯上把瓣膜移植术后60天内发生的心内... 人工瓣心内膜炎(prosthetic valve endocanditis,PVE)是瓣膜移植术后很危险的并发症,尽管应用预防性抗菌素和改进了手术技术使这一并发症明显减少,但很多“心血管中心”报告仍有2%~4%的发生率。习惯上把瓣膜移植术后60天内发生的心内膜炎称作早期 PVE,60天后发生的称作晚期 PVE。早期和晚期 PVE 的临床表现、细菌类型和死亡率均不相同。早期 PVE 的发生率约占瓣膜移植术患者的0.5~1%、晚期 PVE 展开更多
关键词 心内膜炎 移植术 valve PROSTHETIC 瓣环脓肿 抗菌素治疗 生物瓣 革兰氏阴性杆菌 ENDOCARDITIS 敏感试验
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