Propagated sensation along the meridian can occur when acupoints are stimulated by acupuncture or electrical impulses. In this study, participants with notable propagated sensation along the me- ridian were given elec...Propagated sensation along the meridian can occur when acupoints are stimulated by acupuncture or electrical impulses. In this study, participants with notable propagated sensation along the me- ridian were given electro-acupuncture at the Jianyu (LI15) acupoint of the large intestine meridian. When participants stated that the sensation reached the back of their hand, reguJar nervous system action discharge was examined using a physiological recording electrode placed on the superficial branch of the radial nerve. The topographical maps of brain-evoked potential in the primary cortical somatosensory area were also detected. When Guangming (GB37) acupoint in the lower limb and Hegu (LI4) acupoint in the upper limb were stimulated, subjects without propagated sensation along the meridian exhibited a high potential reaction in the corresponding area of the brain cortical somatosensory area. For subjects with a notable propagated sensation along the meridian, the re- action area was larger and extended into the face representative area. These electrophysiological measures directly prove the existence of propagated sensation along the meridian, and the periph- eral stimulated site is consistent with the corresponding primary cortical somatosensory area, which presents a high potential reaction.展开更多
The peripheral driver stimulating theory states that as a driver passes along a certain meridian during acupuncture; the driver provokes nerve sense devices along the meridian, resulting in the nerve impulse entering ...The peripheral driver stimulating theory states that as a driver passes along a certain meridian during acupuncture; the driver provokes nerve sense devices along the meridian, resulting in the nerve impulse entering the central nervous system. Accordingly, volunteers have reported propagated sensations along the meridians (PSM). The present study was designed to utilize a cortical somatosensory-evoked potential (CSEP) topographic map for determining whether stimulation expansion occurs in somatosensory area I when sensation was provoked in individuals with obvious PSM. The sensation was blocked by mechanical compression, and the sensation was imitated in individuals without PSM. Results revealed a red, high-potential signal in the representative area of the lower limbs in individuals with obvious PSM symptoms when the Gall Bladder Meridian (GBM) sensation passed to the head and face. This representative area was near the middle line of the CSEP topographic map, and a red, high-potential signal, which jumps over the representative area of the upper limbs, also appeared in the representative face area, which was at the external region of the CSEP topographic map. However, in individuals exhibiting no PSM, only a red high-potential signal appeared in the representative lower limb area. When Hegu (LI 4) was stimulated in individuals without PSM, an obvious evoked response appeared only in the representative upper limb area. However, when Hegu was stimulated in individuals exhibiting PSM, the response area was larger in the representative upper limb area and extended to the representative face area. When Guangrning (GB 37) was stimulated in PSM individuals, the face representation response disappeared and was confined to a foot representation of the somatosensory area I when PSM was blocked by mechanical pressure. Results suggested that mechanical compression blocked PSM, and corresponding changes were exhibited in the CSEP topographic map. These results provide compelling evidence for the hypothesis that peripheral driver stimulation is the key element in producing PSM.展开更多
The southern continental margin of the South China Sea has documented multiphase continental rifting corresponding to the propagation of seafloor spreading.Here we investigate three multi-channel seismic reflection pr...The southern continental margin of the South China Sea has documented multiphase continental rifting corresponding to the propagation of seafloor spreading.Here we investigate three multi-channel seismic reflection profiles across different segments of the Dangerous Grounds with a NE-SW direction.Stratigraphic correlation reveals that the Cenozoic tectono-stratigraphic framework in the Dangerous Grounds is featured with diachronous rifting,which records the successive spreading of East Subbasin and Southwest Subbasin,South China Sea.By reconstructing the tectono-sedimentary evolution history in different segments,we combine the quantification of the brittle extension,tectonic subsidence,as well as the crustal thinning.Results provide evidence that the extensional stress migrated from northeast to southwest with the progressive propagation of the seafloor spreading in the oceanic basin.Besides,the impact of the tectonic propagation persists even after the cessation of seafloor spreading,evidenced by a longer stretching duration in the West-Dangerous Grounds than that in the eastern area.Moreover,a temporary syn-rift subsidence delay synchronously to the spreading of the adjacent oceanic basin is observed along the southern margin.This observation proves the secondary mantle convection during the seafloor spreading in the southern continental margin,which is related to the propagating rift.展开更多
Modern satellite systems are generally designed to fulfill multiphase-missions. Component /subsystem redundancies are commonly used to achieve high reliability and long life of modern satellite systems. These characte...Modern satellite systems are generally designed to fulfill multiphase-missions. Component /subsystem redundancies are commonly used to achieve high reliability and long life of modern satellite systems. These characteristics have leaded to a critical issue of reliability analysis of satellites that is how to deal with the reliability analysis with multiphase-missions and propagated failures of redundant components. Traditional methods based on the binary decision diagram( BDD) can hardly cope with these issues efficiently. Accordingly, a recursive algorithm method was introduced to facilitate the reliability analysis of satellites. This method was specified for the analysis of static fault tree and it was implemented by generating combination of component failures and carrying out a backward recursive algorithm. The effectiveness of the proposed method was demonstrated through the reliability analysis of a multiphase satellite system with propagated failures.The major advantage of the proposed method is that it does not need composition of BDD and its computational process is automated.展开更多
Heterosis refers to hybrids that exhibit greater vigor in biomass,yield,and adaptation compared with their parents.Nearly all annual crops exhibit heterosis to a certain extent[1].Heterosis is widely utilized in vario...Heterosis refers to hybrids that exhibit greater vigor in biomass,yield,and adaptation compared with their parents.Nearly all annual crops exhibit heterosis to a certain extent[1].Heterosis is widely utilized in various crops including rice,maize,vegetables,and certain perennials[2];however,it cannot be stably inherited in subsequent seasons because of segregation,and hybrid seed production requires complex techniques and substantial resource consumption during every season[3].Apomixis is an asexual mode of seed reproduction that is observed in over 400 plant species.It produces clonal seeds and offspring that are genetically identical to the maternal parent[4].This mechanism has been proposed to revolutionize crop breeding by enabling the rapid fixation and effective utilization of heterosis and elite heterozygous genotypes[5].展开更多
Propagated sensation along meridians (PSM) is a phenomenon that a sensation moves along meridians during stimulation of an acupoint. PSM has an appearance rate of 1.3% among people and have characteristics of low sp...Propagated sensation along meridians (PSM) is a phenomenon that a sensation moves along meridians during stimulation of an acupoint. PSM has an appearance rate of 1.3% among people and have characteristics of low speed, going toward afflicted sites and being blocked by physical pressure which is difficult to be explained by known neural and blood transmission. Volume transmission (VT) is a widespread mode of intercellular communication in the central nervous system that occurs in the extracellular fluid and in the cerebrospinal fluid. VT signals moves from source to target cells via energy gradients leading to diffusion and convection (flow) which is slow, long distance and much less space filling. VT channel diffuse forming a plexus in the extracellular space with two parameters of volume fraction and tortuosity. Some experiments showed an information transmission between adjacent and distant acupoints along meridians cross spinal segments. This process is a cross-excitation between peripheral nerve terminals which is related to nonsynaptic transmission. Some neurotransmitters or neuropeptides such as glutamate, adenosine triphosphate (ATP) and neuropeptide such as substance P, neurokinin A and calcitonin gene-related peptide relate with the cross-excitation which can be regards as VT signals. Comparing the characteristics of PSM and VT, many similar aspects can be found leading to an assumption that PSM is a process of VT in peripheral tissue along meridians. The reason why VT signals transmit along meridians is that the meridian is rich in interstitial fluid under the condition of low hydraulic resistance which has been proven experimentally. According to Darcy's law which descript the flow of interstitial fluid and conservation equation, interstitial fluid will move toward meridians and flow along meridians that restrict the VT signals within the channel and accelerate the flow according to Fick's diffusion law. During the process, a degranulation of histamine from mast cells happens on the route which can expand capillary and increase the blood perfusion and interstitial fluid which had already been observed. The mechanism of PSM is featured by alternative axon reflex (wired transmission, WT) and VT in peripheral tissue along meridians, sending simultaneously a continuous sensate signal to control nerve system which can be felt like a PSM.展开更多
Objective: To investigate the electrical signals propagated along Foot Taiyang Bladder Meridian (BL) in a rat model. Methods: The experiments were performed on Dark-Agouti (DA), DA.lU and Sprague Dawley (SD) r...Objective: To investigate the electrical signals propagated along Foot Taiyang Bladder Meridian (BL) in a rat model. Methods: The experiments were performed on Dark-Agouti (DA), DA.lU and Sprague Dawley (SD) rats. The antidromic electrical stimulation was applied on the nerve innervating "Pishu" (BL 20) to mimic the acupoint electro-acupuncture (EA). The activities recording from adjacent nerve innervating acupoint "Danshu" (BL 19) or "Weishu" (BL 21) were recorded as indics for acupoint, including the mechanical threshold and discharge rate. Results: After mimic EA on BL 20, C and A $ units from adjacent BL 19 or BL 21 were sensitized including the decrease in mechanical threshold and increase in discharge rates in DA, DA.1U and SD rats, especially in DA rats. The average discharge rate increased from 2.40± 0.26 to 6.06± 0.55 and from 1.92±0.42 to 6.17± 1.10 impulse/min (P〈0.01), and the mechanical threshold decreased from 0.52 ± 0.12 to 0.24 ± 0.05 and from 0.27±0.02 to 0.16±0.01 mmol/L (P〈0.01) in C (n=15) and Aδ (n=18) units in DA rats. The net change in discharge rates from C units were 152.5%, 144.7% and 42.4% in DA, DA.1U and SD rats, respectively, among which DA rat's was the highest (P〈0.05). In A δ units, the net change in DA rats were also the highest (221.5%, 139.2% and 49.2% in DA, DA.lU and SD rats). Conclusions: These results showed that mimic acupoint EA activated adjacent acupoints along BL in three rat strains, which might be related to propagated sensation along meridians (PSM). In addition, DA rats were more sensitive and might be a good model animal for PSM research.展开更多
In electrochemical energy storage systems,the sodium-ion battery is typically integrated in the form of a“cell-module-cluster”,but its cross-scale thermal runaway triggering risk and the propagation mechanism remain...In electrochemical energy storage systems,the sodium-ion battery is typically integrated in the form of a“cell-module-cluster”,but its cross-scale thermal runaway triggering risk and the propagation mechanism remain unclear.This study reveals the cross-scale thermal runaway triggering and propagation behavior of sodium-ion batteries of“cell-module-cluster”under overcharge conditions,and investigates the effects of key factors,including module spacing,triggering cell location,and heat dissipation condition,on the thermal runaway propagation behavior.Results demonstrate that the thermal runaway propagation in a module containing the overcharged cell follows a sequential triggering mode,while thermal runaway in the downstream module exhibits a simultaneous triggering mode with greater severity.Furthermore,increasing the module spacing or enhancing the heat dissipation capacity can effectively reduce the heat accumulation and prevent the trigger of thermal runaway.On the above basis,the multi-dimensional evaluation strategy is proposed to quantitatively assess the hazard of sodium-ion battery cluster thermal runaway.The findings serve as a foundation for the safe design of sodium-ion batteries in energy storage systems.展开更多
As a pivotal environmental factor,light,comprising intensity,photoperiod,and spectrum,governs the entire life cycle of strawberries by mediating alterations in the plant’s morphological,physiological,and biochemical ...As a pivotal environmental factor,light,comprising intensity,photoperiod,and spectrum,governs the entire life cycle of strawberries by mediating alterations in the plant’s morphological,physiological,and biochemical traits.Although extensive research has been conducted on light-mediated growth regulation in horticultural crops,most reviews focus primarily on leafy and fruiting vegetables,with limited attention given to berry crops such as strawberries.Additionally,most existing reviews concentrate on one or several growth stages,failing to systematically characterize light’s effects throughout the entire growth cycle and postharvest stage.This review briefly summarizes the regulatory roles of light across key stages of strawberry growth,including seedling propagation,vegetative growth,reproductive growth,and postharvest stages.It seeks to address the knowledge gap by systematically organizing research findings across these developmental phases.The integrated analysis provides a theoretical foundation for designing stage-specific lighting strategies to improve strawberry yield and quality.展开更多
This study investigates the relationship between atmospheric stratification (i.e., static stability given by N^(2)) and the vertical energy transfer of stationary planetary waves, and further illustrates the underlyin...This study investigates the relationship between atmospheric stratification (i.e., static stability given by N^(2)) and the vertical energy transfer of stationary planetary waves, and further illustrates the underlying physical mechanism. Specifically, for the simplified case of constant stratospheric N^(2), the refractive index square of planetary waves has a theoretical tendency to increase first and then decrease with an increased N^(2), whereas the group velocity weakens. Mechanistically, this behavior can be understood as an intensified suppression of vertical isentropic surface displacement caused by meridional heat transport of planetary waves under strong N^(2) conditions. Observational analysis corroborates this finding, demonstrating a reduction in the vertical-propagation velocity of waves with increased N^(2). A linear, quasi- geostrophic, mid-latitude beta-plane model with a constant background westerly wind and a prescribed N^(2) applicable to the stratosphere is used to obtain analytic solutions. In this model, the planetary waves are initiated by steady energy influx from the lower boundary. The analysis indicates that under strong N^(2) conditions, the amplitude of planetary waves can be sufficiently increased by the effective energy convergence due to the slowing vertical energy transfer, resulting in a streamfunction response in this model that contains more energy. For N^(2) with a quasi-linear vertical variation, the results bear a resemblance to the constant case, except that the wave amplitude and oscillating frequency show some vertical variations.展开更多
Excavation causes stress redistribution and affects the stress path during the shearing process of rock.The shear strength of rock varies under different stress paths,and the presence of defects reduces the shear stre...Excavation causes stress redistribution and affects the stress path during the shearing process of rock.The shear strength of rock varies under different stress paths,and the presence of defects reduces the shear strength.To further investigate this phenomenon,this study investigates the shear behaviour of rocks with different shear surface integrities under the influenceof different stress paths through laboratory tests and numerical simulations.The results indicate that the shear strength depends on the stress path and a decrease in the shear surface integrity reduces the degree of dependence.The cohesion and friction angle of the Mohr‒Coulomb criterion decrease with weakening of the shear surface integrity.For different stress paths,the direct shear strength is always greater than that of other shear stress paths.The pattern of changes in the acoustic emission count and cumulative count indirectly reflectsthe above findings.Numerical simulations further indicate that the different principal stress states and normal suppression effects during the shearing process lead to changes in the factors of crack propagation,resulting in different mechanical behaviours under various stress paths.For rocks with different integrity levels,the main reason for the different path dependences of shear strength is that the size of the area affected by shear is different.Shear failure will concentrate on the shear plane when the normal inhibition effect is greater.This study explores the mechanism of rock shear behaviour,providing a theoretical basis for establishing more accurate constitutive models and strength criteria.展开更多
We present a novel approach for calculating the energy budget components during the progressive failure process in cohesive-frictional geomaterials.The energy supplied through external loading can be either stored as ...We present a novel approach for calculating the energy budget components during the progressive failure process in cohesive-frictional geomaterials.The energy supplied through external loading can be either stored as elastic strain energy and plastic energy storage or dissipated through damage growth and irreversible plastic deformation mechanisms.Analytical functions describing energy budget components are derived based on a thermodynamic formulation in geomaterials fracture.The thermodynamically consistent derivation leads to a non-local ductile damage model,which is solved numerically in a non-linear finite element framework.The proposed model captures geomaterial fractures in three benchmark examples,including tensile and biaxial-compressive shear scenarios and slope stability analysis.The aspects of shear fracture propagation and energy budget mechanisms are elaborately investigated,considering different material properties and stochastic distributions.The numerical results are validated against existing experimental data and other analytical methods.The model provides a physics-based understanding of energy budget in geomaterials fracture,leading to advances in ground improvement and other geotechnical supporting systems.展开更多
Hydraulic fracturing serves as a critical technology for reservoir stimulation in deep coalbed methane(CBM)development,where the mechanical properties of gangue layers exert a significant control on fracture propagati...Hydraulic fracturing serves as a critical technology for reservoir stimulation in deep coalbed methane(CBM)development,where the mechanical properties of gangue layers exert a significant control on fracture propagation behavior.To address the unclear mechanisms governing fracture penetration across coal-gangue interfaces,this study employs the Continuum-Discontinuum Element Method(CDEM)to simulate and analyze the vertical propagation of hydraulic fractures initiating within coal seams,based on geomechanical parameters derived from the deep Benxi Formation coal seams in the southeastern Ordos Basin.The investigation systematically examines the influence of geological and operational parameters on cross-interfacial fracture growth.Results demonstrate that vertical stress difference,elastic modulus contrast between coal and gangue layers,interfacial stress differential,and interfacial cohesion at coal-gangue interfaces are critical factors governing hydraulic fracture penetration through these interfaces.High vertical stress differences(>3 MPa)inhibit interfacial dilation,promoting predominant crosslayer fracture propagation.Reduced interfacial stress contrasts and enhanced interfacial cohesion facilitate fracture penetration across interfaces.Furthermore,smaller elastic modulus contrasts between coal and gangue correlate with increased interfacial aperture.Finally,lower injection rates effectively suppress vertical fracture propagation in deep coal reservoirs.This study elucidates the characteristics and mechanisms governing cross-layer fracture propagation in coal–rock composites with interbedded partings,and delineates the dynamic evolution laws and dominant controlling factors involved.Thefindings provide critical theoretical insights for the optimization of fracture design and the efficient development of deep coalbed methane reservoirs.展开更多
Freezing and thawing processes play a crucial role in causing significant deformation and damage to layered soft rocks in cold region due to daily and seasonal temperature fluctuations.However,the frost heave mechanis...Freezing and thawing processes play a crucial role in causing significant deformation and damage to layered soft rocks in cold region due to daily and seasonal temperature fluctuations.However,the frost heave mechanism of the rocks and their mechanical behaviors at the meso-scale still require further investigations.For this,we focused on carbonaceous slate reported in a high-altitude cold region,in terms of mineral composition,content,and microstructure.The strength and failure of mineral grain(MG)interfaces are studied using three-point-bending tests,in order to explore the evolution of mode I fracture toughness and tensile strength with the Dugdale-Barenblatt model and the Weibull distribution model.The results indicate that the damage of slate involves the initiation and propagation of microfracture networks at clay MG interfaces(bedding planes),driven by frost heave pressure at macroscopic and microscopic scales.This process causes the detachment of some MGs,resulting in fracture surfaces with a distinctive pulled-off planar structure.The hydrophilicity of clay MGs,interfacial strengths,and microfracture structures contribute to the freeze-thaw damage.As the number of freeze-thaw cycles increases,the effective area per unit decreases,leading to an exponentially decreasing in mode I fracture toughness and tensile strength at MG interfaces.Approximately 67%strength degradation occurs after 14 freeze-thaw cycles.This provides theoretical basis and experimental methods for better understanding the damage and deterioration behaviors of layered soft rocks in cold region under natural freeze-thaw cycles.展开更多
Shrublands and grasslands,which constitute approximately 70%of Australia’s vegetation,play a critical role in global wildfire-prone regions.To advance the understanding of grass fire spread,a three-dimensional,physic...Shrublands and grasslands,which constitute approximately 70%of Australia’s vegetation,play a critical role in global wildfire-prone regions.To advance the understanding of grass fire spread,a three-dimensional,physicsbased fire model provides valuable insights into fire dynamics.However,such models are computationally intensive and time-consuming.To address these challenges,we constructed an extensive numerical database comprising 64,000 high-fidelity wildfire simulation cases and implemented a Long Short-Term Memory neural network architecture.The model demonstrates strong predictive performance,achieving a coefficient of determination(R2)of 0.96 on training data,indicating excellent agreement with the physics-based simulation outputs.By utilizing coordinates from five reference points to predict fire front movement,this approach offers a novel method for analysing fire dynamics in homogeneous fuel beds with an average deviation of less than 2.5%.Combining the strengths of physics-based modelling and deep learning,our research enhances fire spread prediction accuracy of over 95%while significantly reducing computational demands.Future efforts will focus on refining the model,expanding the dataset,and incorporating additional variables to improve predictive capabilities and operational applicability.展开更多
The stability of rock slopes is frequently controlled by the initiation and propagation of inherent dominant cracks.This study systematically investigated these processes in valley slopes by combining fracture-mechani...The stability of rock slopes is frequently controlled by the initiation and propagation of inherent dominant cracks.This study systematically investigated these processes in valley slopes by combining fracture-mechanics analysis with transparent soil model tests.An analytical expression for the stress field at the dominant crack tip was derived from the slope stress distribution by superposing the corresponding stress intensity factors(SIFs).The theoretical predictions were then validated against observations from transparent soil model tests.The influences of slope angle(β),crack inclination angle(α),crack position parameter(b),and crack length parameter(h)on crack initiation and propagation were quantified.The results indicated that:(1)cracks at the slope crest tended to propagate in shear mode,and the shear crack initiation angle(θ_(s))was approximately 8°.Cracks at the slope toe might propagate in either tensile or shear mode.(2)θ_(s) at the slope crest increased withβ,b,and l,and decreased withα.The maximum change inθ_(s) induced by the considered parameters was approximately 30°.(3)The tensile crack initiation angle(θ_(t))at the slop toe decreased withβ,α,and l,while the influence of b was comparatively minor.The maximum change inθ_(t) caused by individual parameters ranged approximately from 25°to 60°.Predicted crack propagation modes and directions showed good agreement with experimental results.These findings provide theoretical guidance for stability assessments of valley slopes controlled by dominant crack propagation.展开更多
The influence of different solution and aging conditions on the microstructure,impact toughness,and crack initiation and propagation mechanisms of the novel α+β titanium alloy Ti6422 was systematically investigated....The influence of different solution and aging conditions on the microstructure,impact toughness,and crack initiation and propagation mechanisms of the novel α+β titanium alloy Ti6422 was systematically investigated.By adjusting the furnace cooling time after solution treatment and the aging temperature,Ti6422 alloy samples were developed with a multi-level lamellar microstructure,in-cluding microscaleαcolonies and α_(p) lamellae,as well as nanoscale α_(s) phases.Extending the furnace cooling time after solution treatment at 920℃ for 1 h from 240 to 540 min,followed by aging at 600℃ for 6 h,increased the α_(p) lamella content,reduced the α_(s) phase content,expanded theαcolonies and α_(p) lamellae size,and improved the impact toughness from 22.7 to 53.8 J/cm^(2).Additionally,under the same solution treatment,raising the aging temperature from 500 to 700℃ resulted in a decrease in the α_(s) phase content and a growth in the thickness of the α_(p) lamella and α_(s) phase.The impact toughness increased significantly with these changes.Samples with high α_(p) lamellae content or large α_(s) phase size exhibited high crack initiation and propagation energies.Impact deformation caused severe kinking of the α_(p) lamellae in crack initiation and propagation areas,leading to a uniform and high-density kernel average misorientation(KAM)distribu-tion,enhancing plastic deformation coordination and uniformity.Moreover,the multidirectional arrangement of coarserαcolonies and α_(p) lamellae continuously deflect the crack propagation direction,inhibiting crack propagation.展开更多
This study investigates the effects of ocean boundaries on modal shapes in very-low-frequency(VLF,1–10 Hz)sound propagation through the deep ocean.Utilizing a normal mode solution formulated in terms of parabolic cyl...This study investigates the effects of ocean boundaries on modal shapes in very-low-frequency(VLF,1–10 Hz)sound propagation through the deep ocean.Utilizing a normal mode solution formulated in terms of parabolic cylinder functions(PCF),we demonstrate that boundary interactions induce a phase change reduction below-πat frequencies of several hertz.This reduction,in turn,forces a key transition in the solution,shifting the order of the PCF from integer to non-integer values.Analysis of the characteristic shape of the PCF versus its order reveals that these boundary-influenced modes exhibit an energy shift toward deeper regions and a weakened axial convergence of the underwater sound field.展开更多
Optical non-reciprocity is a fundamental phenomenon in photonics.It is crucial for developing devices that rely on directional signal control,such as optical isolators and circulators.However,most research in this fie...Optical non-reciprocity is a fundamental phenomenon in photonics.It is crucial for developing devices that rely on directional signal control,such as optical isolators and circulators.However,most research in this field has focused on systems in equilibrium or steady states.In this work,we demonstrate a room-temperature Rydberg atomic platform where the unidirectional propagation of light acts as a switch to mediate time-crystalline-like collective oscillations through atomic synchronization.展开更多
基金supported by the General Project of the National Natural Science Foundation of China,No.30973720the Natural Science Foundation of Fujian Province in China,No.2011J01192Free Topics of Fujian Provincial Science & Technology Ministry in China,No.2012fjzyyk-6
文摘Propagated sensation along the meridian can occur when acupoints are stimulated by acupuncture or electrical impulses. In this study, participants with notable propagated sensation along the me- ridian were given electro-acupuncture at the Jianyu (LI15) acupoint of the large intestine meridian. When participants stated that the sensation reached the back of their hand, reguJar nervous system action discharge was examined using a physiological recording electrode placed on the superficial branch of the radial nerve. The topographical maps of brain-evoked potential in the primary cortical somatosensory area were also detected. When Guangming (GB37) acupoint in the lower limb and Hegu (LI4) acupoint in the upper limb were stimulated, subjects without propagated sensation along the meridian exhibited a high potential reaction in the corresponding area of the brain cortical somatosensory area. For subjects with a notable propagated sensation along the meridian, the re- action area was larger and extended into the face representative area. These electrophysiological measures directly prove the existence of propagated sensation along the meridian, and the periph- eral stimulated site is consistent with the corresponding primary cortical somatosensory area, which presents a high potential reaction.
基金the National Natural Science Foundation of China, No.30973720the Science Research Foundation of Ministry of Health & United Fujian Provincial Health and Education Project for Tackling the Key Research of China, No.WKJ2005-2-004
文摘The peripheral driver stimulating theory states that as a driver passes along a certain meridian during acupuncture; the driver provokes nerve sense devices along the meridian, resulting in the nerve impulse entering the central nervous system. Accordingly, volunteers have reported propagated sensations along the meridians (PSM). The present study was designed to utilize a cortical somatosensory-evoked potential (CSEP) topographic map for determining whether stimulation expansion occurs in somatosensory area I when sensation was provoked in individuals with obvious PSM. The sensation was blocked by mechanical compression, and the sensation was imitated in individuals without PSM. Results revealed a red, high-potential signal in the representative area of the lower limbs in individuals with obvious PSM symptoms when the Gall Bladder Meridian (GBM) sensation passed to the head and face. This representative area was near the middle line of the CSEP topographic map, and a red, high-potential signal, which jumps over the representative area of the upper limbs, also appeared in the representative face area, which was at the external region of the CSEP topographic map. However, in individuals exhibiting no PSM, only a red high-potential signal appeared in the representative lower limb area. When Hegu (LI 4) was stimulated in individuals without PSM, an obvious evoked response appeared only in the representative upper limb area. However, when Hegu was stimulated in individuals exhibiting PSM, the response area was larger in the representative upper limb area and extended to the representative face area. When Guangrning (GB 37) was stimulated in PSM individuals, the face representation response disappeared and was confined to a foot representation of the somatosensory area I when PSM was blocked by mechanical pressure. Results suggested that mechanical compression blocked PSM, and corresponding changes were exhibited in the CSEP topographic map. These results provide compelling evidence for the hypothesis that peripheral driver stimulation is the key element in producing PSM.
基金financially supported by the Open Fund of Hubei Key Laboratory of Marine Geological Resources(No.MGR202004)the National Natural Science Foundation of China(Nos.41890811,41676027,41906070)。
文摘The southern continental margin of the South China Sea has documented multiphase continental rifting corresponding to the propagation of seafloor spreading.Here we investigate three multi-channel seismic reflection profiles across different segments of the Dangerous Grounds with a NE-SW direction.Stratigraphic correlation reveals that the Cenozoic tectono-stratigraphic framework in the Dangerous Grounds is featured with diachronous rifting,which records the successive spreading of East Subbasin and Southwest Subbasin,South China Sea.By reconstructing the tectono-sedimentary evolution history in different segments,we combine the quantification of the brittle extension,tectonic subsidence,as well as the crustal thinning.Results provide evidence that the extensional stress migrated from northeast to southwest with the progressive propagation of the seafloor spreading in the oceanic basin.Besides,the impact of the tectonic propagation persists even after the cessation of seafloor spreading,evidenced by a longer stretching duration in the West-Dangerous Grounds than that in the eastern area.Moreover,a temporary syn-rift subsidence delay synchronously to the spreading of the adjacent oceanic basin is observed along the southern margin.This observation proves the secondary mantle convection during the seafloor spreading in the southern continental margin,which is related to the propagating rift.
文摘Modern satellite systems are generally designed to fulfill multiphase-missions. Component /subsystem redundancies are commonly used to achieve high reliability and long life of modern satellite systems. These characteristics have leaded to a critical issue of reliability analysis of satellites that is how to deal with the reliability analysis with multiphase-missions and propagated failures of redundant components. Traditional methods based on the binary decision diagram( BDD) can hardly cope with these issues efficiently. Accordingly, a recursive algorithm method was introduced to facilitate the reliability analysis of satellites. This method was specified for the analysis of static fault tree and it was implemented by generating combination of component failures and carrying out a backward recursive algorithm. The effectiveness of the proposed method was demonstrated through the reliability analysis of a multiphase satellite system with propagated failures.The major advantage of the proposed method is that it does not need composition of BDD and its computational process is automated.
基金supported by the National Natural Science Foundation of China(32025028 and 32188102)the National Key Research and Development Program of China(2022YFF1003304)the Agricultural Science and Technology Innovation Program(CAAS-ASTIP-2021-CNRRI)。
文摘Heterosis refers to hybrids that exhibit greater vigor in biomass,yield,and adaptation compared with their parents.Nearly all annual crops exhibit heterosis to a certain extent[1].Heterosis is widely utilized in various crops including rice,maize,vegetables,and certain perennials[2];however,it cannot be stably inherited in subsequent seasons because of segregation,and hybrid seed production requires complex techniques and substantial resource consumption during every season[3].Apomixis is an asexual mode of seed reproduction that is observed in over 400 plant species.It produces clonal seeds and offspring that are genetically identical to the maternal parent[4].This mechanism has been proposed to revolutionize crop breeding by enabling the rapid fixation and effective utilization of heterosis and elite heterozygous genotypes[5].
基金Supported by National Key Basic Research Program(973 No. 2010CB530507)National Nature Science Foundation(No. 81173206)
文摘Propagated sensation along meridians (PSM) is a phenomenon that a sensation moves along meridians during stimulation of an acupoint. PSM has an appearance rate of 1.3% among people and have characteristics of low speed, going toward afflicted sites and being blocked by physical pressure which is difficult to be explained by known neural and blood transmission. Volume transmission (VT) is a widespread mode of intercellular communication in the central nervous system that occurs in the extracellular fluid and in the cerebrospinal fluid. VT signals moves from source to target cells via energy gradients leading to diffusion and convection (flow) which is slow, long distance and much less space filling. VT channel diffuse forming a plexus in the extracellular space with two parameters of volume fraction and tortuosity. Some experiments showed an information transmission between adjacent and distant acupoints along meridians cross spinal segments. This process is a cross-excitation between peripheral nerve terminals which is related to nonsynaptic transmission. Some neurotransmitters or neuropeptides such as glutamate, adenosine triphosphate (ATP) and neuropeptide such as substance P, neurokinin A and calcitonin gene-related peptide relate with the cross-excitation which can be regards as VT signals. Comparing the characteristics of PSM and VT, many similar aspects can be found leading to an assumption that PSM is a process of VT in peripheral tissue along meridians. The reason why VT signals transmit along meridians is that the meridian is rich in interstitial fluid under the condition of low hydraulic resistance which has been proven experimentally. According to Darcy's law which descript the flow of interstitial fluid and conservation equation, interstitial fluid will move toward meridians and flow along meridians that restrict the VT signals within the channel and accelerate the flow according to Fick's diffusion law. During the process, a degranulation of histamine from mast cells happens on the route which can expand capillary and increase the blood perfusion and interstitial fluid which had already been observed. The mechanism of PSM is featured by alternative axon reflex (wired transmission, WT) and VT in peripheral tissue along meridians, sending simultaneously a continuous sensate signal to control nerve system which can be felt like a PSM.
基金Supported by the National Natural Science Foundation of China(No.81200604)
文摘Objective: To investigate the electrical signals propagated along Foot Taiyang Bladder Meridian (BL) in a rat model. Methods: The experiments were performed on Dark-Agouti (DA), DA.lU and Sprague Dawley (SD) rats. The antidromic electrical stimulation was applied on the nerve innervating "Pishu" (BL 20) to mimic the acupoint electro-acupuncture (EA). The activities recording from adjacent nerve innervating acupoint "Danshu" (BL 19) or "Weishu" (BL 21) were recorded as indics for acupoint, including the mechanical threshold and discharge rate. Results: After mimic EA on BL 20, C and A $ units from adjacent BL 19 or BL 21 were sensitized including the decrease in mechanical threshold and increase in discharge rates in DA, DA.1U and SD rats, especially in DA rats. The average discharge rate increased from 2.40± 0.26 to 6.06± 0.55 and from 1.92±0.42 to 6.17± 1.10 impulse/min (P〈0.01), and the mechanical threshold decreased from 0.52 ± 0.12 to 0.24 ± 0.05 and from 0.27±0.02 to 0.16±0.01 mmol/L (P〈0.01) in C (n=15) and Aδ (n=18) units in DA rats. The net change in discharge rates from C units were 152.5%, 144.7% and 42.4% in DA, DA.1U and SD rats, respectively, among which DA rat's was the highest (P〈0.05). In A δ units, the net change in DA rats were also the highest (221.5%, 139.2% and 49.2% in DA, DA.lU and SD rats). Conclusions: These results showed that mimic acupoint EA activated adjacent acupoints along BL in three rat strains, which might be related to propagated sensation along meridians (PSM). In addition, DA rats were more sensitive and might be a good model animal for PSM research.
基金supported by the Anhui Quality Infrastructure Standardization Project(Grant No.2024MKSO7)the Science and Technology Project of State Grid(SGAHDK00DJJS2310027)the Anhui Provincial Natural Science Foundation(Grant No.2208085UD03).
文摘In electrochemical energy storage systems,the sodium-ion battery is typically integrated in the form of a“cell-module-cluster”,but its cross-scale thermal runaway triggering risk and the propagation mechanism remain unclear.This study reveals the cross-scale thermal runaway triggering and propagation behavior of sodium-ion batteries of“cell-module-cluster”under overcharge conditions,and investigates the effects of key factors,including module spacing,triggering cell location,and heat dissipation condition,on the thermal runaway propagation behavior.Results demonstrate that the thermal runaway propagation in a module containing the overcharged cell follows a sequential triggering mode,while thermal runaway in the downstream module exhibits a simultaneous triggering mode with greater severity.Furthermore,increasing the module spacing or enhancing the heat dissipation capacity can effectively reduce the heat accumulation and prevent the trigger of thermal runaway.On the above basis,the multi-dimensional evaluation strategy is proposed to quantitatively assess the hazard of sodium-ion battery cluster thermal runaway.The findings serve as a foundation for the safe design of sodium-ion batteries in energy storage systems.
基金supported by National Key Research and Development Program of China(2023YFF1001700)the Unveiling and Leading Projects(2022kj05)+1 种基金Yafu Technology Innovation Team of Jiangsu Vocational College of Agriculture and Forestry(2024kj02)the Innovation&Entrepreneurship Training Program for College Students of Qingdao Agricultural University(QNDC20250149).
文摘As a pivotal environmental factor,light,comprising intensity,photoperiod,and spectrum,governs the entire life cycle of strawberries by mediating alterations in the plant’s morphological,physiological,and biochemical traits.Although extensive research has been conducted on light-mediated growth regulation in horticultural crops,most reviews focus primarily on leafy and fruiting vegetables,with limited attention given to berry crops such as strawberries.Additionally,most existing reviews concentrate on one or several growth stages,failing to systematically characterize light’s effects throughout the entire growth cycle and postharvest stage.This review briefly summarizes the regulatory roles of light across key stages of strawberry growth,including seedling propagation,vegetative growth,reproductive growth,and postharvest stages.It seeks to address the knowledge gap by systematically organizing research findings across these developmental phases.The integrated analysis provides a theoretical foundation for designing stage-specific lighting strategies to improve strawberry yield and quality.
基金supported by the National Natural Science Foundation of China(Grant No.42261134532,42405059,and U2342212)。
文摘This study investigates the relationship between atmospheric stratification (i.e., static stability given by N^(2)) and the vertical energy transfer of stationary planetary waves, and further illustrates the underlying physical mechanism. Specifically, for the simplified case of constant stratospheric N^(2), the refractive index square of planetary waves has a theoretical tendency to increase first and then decrease with an increased N^(2), whereas the group velocity weakens. Mechanistically, this behavior can be understood as an intensified suppression of vertical isentropic surface displacement caused by meridional heat transport of planetary waves under strong N^(2) conditions. Observational analysis corroborates this finding, demonstrating a reduction in the vertical-propagation velocity of waves with increased N^(2). A linear, quasi- geostrophic, mid-latitude beta-plane model with a constant background westerly wind and a prescribed N^(2) applicable to the stratosphere is used to obtain analytic solutions. In this model, the planetary waves are initiated by steady energy influx from the lower boundary. The analysis indicates that under strong N^(2) conditions, the amplitude of planetary waves can be sufficiently increased by the effective energy convergence due to the slowing vertical energy transfer, resulting in a streamfunction response in this model that contains more energy. For N^(2) with a quasi-linear vertical variation, the results bear a resemblance to the constant case, except that the wave amplitude and oscillating frequency show some vertical variations.
基金support from the Postgraduate Research&Practice Innovation Program of Jiangsu Province,China(Grant No.KYCX24_2822)the Graduate Innovation Program of China University of Mining and Technology(Grant No.2024WLKXJ205)the National Natural Science Foundation of China(Grant No.52474157).
文摘Excavation causes stress redistribution and affects the stress path during the shearing process of rock.The shear strength of rock varies under different stress paths,and the presence of defects reduces the shear strength.To further investigate this phenomenon,this study investigates the shear behaviour of rocks with different shear surface integrities under the influenceof different stress paths through laboratory tests and numerical simulations.The results indicate that the shear strength depends on the stress path and a decrease in the shear surface integrity reduces the degree of dependence.The cohesion and friction angle of the Mohr‒Coulomb criterion decrease with weakening of the shear surface integrity.For different stress paths,the direct shear strength is always greater than that of other shear stress paths.The pattern of changes in the acoustic emission count and cumulative count indirectly reflectsthe above findings.Numerical simulations further indicate that the different principal stress states and normal suppression effects during the shearing process lead to changes in the factors of crack propagation,resulting in different mechanical behaviours under various stress paths.For rocks with different integrity levels,the main reason for the different path dependences of shear strength is that the size of the area affected by shear is different.Shear failure will concentrate on the shear plane when the normal inhibition effect is greater.This study explores the mechanism of rock shear behaviour,providing a theoretical basis for establishing more accurate constitutive models and strength criteria.
基金supported by the National Natural Science Foundation of China(Grant No.52179128)the Sand Hazards and Opportunities for Resilience,Energy,and Sustainability(SHORES)Center,funded by Tamkeen under the NYUAD Research Institute Award CG013.
文摘We present a novel approach for calculating the energy budget components during the progressive failure process in cohesive-frictional geomaterials.The energy supplied through external loading can be either stored as elastic strain energy and plastic energy storage or dissipated through damage growth and irreversible plastic deformation mechanisms.Analytical functions describing energy budget components are derived based on a thermodynamic formulation in geomaterials fracture.The thermodynamically consistent derivation leads to a non-local ductile damage model,which is solved numerically in a non-linear finite element framework.The proposed model captures geomaterial fractures in three benchmark examples,including tensile and biaxial-compressive shear scenarios and slope stability analysis.The aspects of shear fracture propagation and energy budget mechanisms are elaborately investigated,considering different material properties and stochastic distributions.The numerical results are validated against existing experimental data and other analytical methods.The model provides a physics-based understanding of energy budget in geomaterials fracture,leading to advances in ground improvement and other geotechnical supporting systems.
文摘Hydraulic fracturing serves as a critical technology for reservoir stimulation in deep coalbed methane(CBM)development,where the mechanical properties of gangue layers exert a significant control on fracture propagation behavior.To address the unclear mechanisms governing fracture penetration across coal-gangue interfaces,this study employs the Continuum-Discontinuum Element Method(CDEM)to simulate and analyze the vertical propagation of hydraulic fractures initiating within coal seams,based on geomechanical parameters derived from the deep Benxi Formation coal seams in the southeastern Ordos Basin.The investigation systematically examines the influence of geological and operational parameters on cross-interfacial fracture growth.Results demonstrate that vertical stress difference,elastic modulus contrast between coal and gangue layers,interfacial stress differential,and interfacial cohesion at coal-gangue interfaces are critical factors governing hydraulic fracture penetration through these interfaces.High vertical stress differences(>3 MPa)inhibit interfacial dilation,promoting predominant crosslayer fracture propagation.Reduced interfacial stress contrasts and enhanced interfacial cohesion facilitate fracture penetration across interfaces.Furthermore,smaller elastic modulus contrasts between coal and gangue correlate with increased interfacial aperture.Finally,lower injection rates effectively suppress vertical fracture propagation in deep coal reservoirs.This study elucidates the characteristics and mechanisms governing cross-layer fracture propagation in coal–rock composites with interbedded partings,and delineates the dynamic evolution laws and dominant controlling factors involved.Thefindings provide critical theoretical insights for the optimization of fracture design and the efficient development of deep coalbed methane reservoirs.
基金support of National Natural Science Foundation of China(Grant No.U24A20184)Science and Technology Planning Project of Xizang Autonomous Region,China(Grant Nos.XZ202201ZY0021G,XZ202401ZY0085).
文摘Freezing and thawing processes play a crucial role in causing significant deformation and damage to layered soft rocks in cold region due to daily and seasonal temperature fluctuations.However,the frost heave mechanism of the rocks and their mechanical behaviors at the meso-scale still require further investigations.For this,we focused on carbonaceous slate reported in a high-altitude cold region,in terms of mineral composition,content,and microstructure.The strength and failure of mineral grain(MG)interfaces are studied using three-point-bending tests,in order to explore the evolution of mode I fracture toughness and tensile strength with the Dugdale-Barenblatt model and the Weibull distribution model.The results indicate that the damage of slate involves the initiation and propagation of microfracture networks at clay MG interfaces(bedding planes),driven by frost heave pressure at macroscopic and microscopic scales.This process causes the detachment of some MGs,resulting in fracture surfaces with a distinctive pulled-off planar structure.The hydrophilicity of clay MGs,interfacial strengths,and microfracture structures contribute to the freeze-thaw damage.As the number of freeze-thaw cycles increases,the effective area per unit decreases,leading to an exponentially decreasing in mode I fracture toughness and tensile strength at MG interfaces.Approximately 67%strength degradation occurs after 14 freeze-thaw cycles.This provides theoretical basis and experimental methods for better understanding the damage and deterioration behaviors of layered soft rocks in cold region under natural freeze-thaw cycles.
基金funded by the National Natural Science Foundation of China(NSFC No.52322610)Hong Kong Research Grants Council Theme-based Research Scheme(T22-505/19-N)Furthermore,this research was undertaken with the assistance of computational resources from the National Computational Infrastructure(NCI Australia),an NCRISenabled capability supported by the Australian Government.
文摘Shrublands and grasslands,which constitute approximately 70%of Australia’s vegetation,play a critical role in global wildfire-prone regions.To advance the understanding of grass fire spread,a three-dimensional,physicsbased fire model provides valuable insights into fire dynamics.However,such models are computationally intensive and time-consuming.To address these challenges,we constructed an extensive numerical database comprising 64,000 high-fidelity wildfire simulation cases and implemented a Long Short-Term Memory neural network architecture.The model demonstrates strong predictive performance,achieving a coefficient of determination(R2)of 0.96 on training data,indicating excellent agreement with the physics-based simulation outputs.By utilizing coordinates from five reference points to predict fire front movement,this approach offers a novel method for analysing fire dynamics in homogeneous fuel beds with an average deviation of less than 2.5%.Combining the strengths of physics-based modelling and deep learning,our research enhances fire spread prediction accuracy of over 95%while significantly reducing computational demands.Future efforts will focus on refining the model,expanding the dataset,and incorporating additional variables to improve predictive capabilities and operational applicability.
基金financially supported by the National Nature Science Foundation of China(Nos.52379110 and 42207222)the Key Technologies for Accurate Diagnosis and Intelligent Prevention and Control of Slope Hazards in Open Pit Mines,181 Major R&D projects of Metallurgical Corporation of China Ltd。
文摘The stability of rock slopes is frequently controlled by the initiation and propagation of inherent dominant cracks.This study systematically investigated these processes in valley slopes by combining fracture-mechanics analysis with transparent soil model tests.An analytical expression for the stress field at the dominant crack tip was derived from the slope stress distribution by superposing the corresponding stress intensity factors(SIFs).The theoretical predictions were then validated against observations from transparent soil model tests.The influences of slope angle(β),crack inclination angle(α),crack position parameter(b),and crack length parameter(h)on crack initiation and propagation were quantified.The results indicated that:(1)cracks at the slope crest tended to propagate in shear mode,and the shear crack initiation angle(θ_(s))was approximately 8°.Cracks at the slope toe might propagate in either tensile or shear mode.(2)θ_(s) at the slope crest increased withβ,b,and l,and decreased withα.The maximum change inθ_(s) induced by the considered parameters was approximately 30°.(3)The tensile crack initiation angle(θ_(t))at the slop toe decreased withβ,α,and l,while the influence of b was comparatively minor.The maximum change inθ_(t) caused by individual parameters ranged approximately from 25°to 60°.Predicted crack propagation modes and directions showed good agreement with experimental results.These findings provide theoretical guidance for stability assessments of valley slopes controlled by dominant crack propagation.
基金supported by the National Natural Science Foundation of China(No.52090041).
文摘The influence of different solution and aging conditions on the microstructure,impact toughness,and crack initiation and propagation mechanisms of the novel α+β titanium alloy Ti6422 was systematically investigated.By adjusting the furnace cooling time after solution treatment and the aging temperature,Ti6422 alloy samples were developed with a multi-level lamellar microstructure,in-cluding microscaleαcolonies and α_(p) lamellae,as well as nanoscale α_(s) phases.Extending the furnace cooling time after solution treatment at 920℃ for 1 h from 240 to 540 min,followed by aging at 600℃ for 6 h,increased the α_(p) lamella content,reduced the α_(s) phase content,expanded theαcolonies and α_(p) lamellae size,and improved the impact toughness from 22.7 to 53.8 J/cm^(2).Additionally,under the same solution treatment,raising the aging temperature from 500 to 700℃ resulted in a decrease in the α_(s) phase content and a growth in the thickness of the α_(p) lamella and α_(s) phase.The impact toughness increased significantly with these changes.Samples with high α_(p) lamellae content or large α_(s) phase size exhibited high crack initiation and propagation energies.Impact deformation caused severe kinking of the α_(p) lamellae in crack initiation and propagation areas,leading to a uniform and high-density kernel average misorientation(KAM)distribu-tion,enhancing plastic deformation coordination and uniformity.Moreover,the multidirectional arrangement of coarserαcolonies and α_(p) lamellae continuously deflect the crack propagation direction,inhibiting crack propagation.
基金Project supported by the National Natural Science Foundation of China(Grant No.12204128)。
文摘This study investigates the effects of ocean boundaries on modal shapes in very-low-frequency(VLF,1–10 Hz)sound propagation through the deep ocean.Utilizing a normal mode solution formulated in terms of parabolic cylinder functions(PCF),we demonstrate that boundary interactions induce a phase change reduction below-πat frequencies of several hertz.This reduction,in turn,forces a key transition in the solution,shifting the order of the PCF from integer to non-integer values.Analysis of the characteristic shape of the PCF versus its order reveals that these boundary-influenced modes exhibit an energy shift toward deeper regions and a weakened axial convergence of the underwater sound field.
基金supported by the National Natural Science Foundation of China (Grant No.12274131)the Innovation Program for Quantum Science and Technology (Grant No.2024ZD0300101)。
文摘Optical non-reciprocity is a fundamental phenomenon in photonics.It is crucial for developing devices that rely on directional signal control,such as optical isolators and circulators.However,most research in this field has focused on systems in equilibrium or steady states.In this work,we demonstrate a room-temperature Rydberg atomic platform where the unidirectional propagation of light acts as a switch to mediate time-crystalline-like collective oscillations through atomic synchronization.