Social sciences positioned populism as a strategy to secure power/strength, a genuine political way, but besides it is positioned as an ideology, which divides society into two homogenous, antagonistic groups, brings ...Social sciences positioned populism as a strategy to secure power/strength, a genuine political way, but besides it is positioned as an ideology, which divides society into two homogenous, antagonistic groups, brings society and elites face to face. Furthermore it is defined, as an ideology that wants politics to represent the society＇s general will. It is accepted that media and its production ＂logic＂ provides appropriate tools for populism development. In Turkey, which is governed by neoconservative and neo-liberal power, media populism has been the most used political communication strategy in recent years. Communication strategies, when there is a need to arouse and direct interest of the public opinion and for agenda setting processes; complexity, reduction, personalization, accusation, sentimentalizing, targeting, dramatization, alienation and creation of pseudo events, are frequently used. Most of the political actors appeal to media populism when they need to lean on to the society, disseminate the charismatic leader discourse, reduce the value of the discourses belonging to opponents, prove that they are representing the common goods and benefits. This study relates to direct-indirect practices of government＇s populism strategies. Within this context, creating legitimacy on political power by media populism in Turkey is assumed to be the most powerful method.展开更多
A potential global power transition characterized by emerging economies of BRICS where China is the likely leading contender against the United States as the only global hegemon seems inevitable.The increasingly multi...A potential global power transition characterized by emerging economies of BRICS where China is the likely leading contender against the United States as the only global hegemon seems inevitable.The increasingly multipolar world is evidenced by the attention given to right-wing populism in Europe and USA attributed to China’s aggressive approach to international trade through its stealth entry and subsequent investments in global political-economy.China’s presence in Africa and Trump’s America first policy’s attempt to open“new business frontiers”in emerging economies of Asia and Africa in order to contain Chinese influence and threat in global hegemony are interesting happenstances that require closer scrutiny.Kenya,the biggest economy in East Africa,which is among the fastest growing regions globally,is the gateway to the East African Common Market.Historically,Kenya has a policy of non-alignment in international relations making it possible to receive FDI from both China and the US but with highly contested elections.Therefore,Kenya presents a perfect laboratory for examining the emerging power-shift in global political-economy as the country grapples with traditionally chaotic electoral power transitions and the two biggest economies in the world compete for business in Nairobi.The 2017 elections not only betrayed the international community’s commitment to Western values of human rights and democracy,but also revealed the challenges of governance in post-World War II global liberalism characterized by sophisticated media institutional spaces.展开更多
Thanks to globalization and the emergence of the digital,capitalism progressively arrives to the stage of neoliberal financial hegemony. Therefore,in Europe today,Marxism remains powerful only in the form of leftist p...Thanks to globalization and the emergence of the digital,capitalism progressively arrives to the stage of neoliberal financial hegemony. Therefore,in Europe today,Marxism remains powerful only in the form of leftist populism among the"radical left",as social-democrats and socialists have been largely absorbed by the right. However,because the struggle for hegemony is not only a binary relationship but also a triangular relationship,the only conceivable emancipation strategy is the old Marxist one,which is both dual,popular class against ruling class,and triangular,between three social forces (plus the competent). In this way,the popular class can access itself competence-power by associating with the competent and putting them under its own hegemony.展开更多
In the presented paper,the author starts with diagnosing the state of research on populism and biopolitics simultaneously.The author states that most often in the literature the topic of populism(Laclau,Mouffe,Mudde,a...In the presented paper,the author starts with diagnosing the state of research on populism and biopolitics simultaneously.The author states that most often in the literature the topic of populism(Laclau,Mouffe,Mudde,and Panizza)is considered separately from the problems related to biopolitics(Foucault,Negri,Agamben,and Esposito).The author would like to change this separation by bringing these two discourses closer together.The author’s main aim is to rethink populism from a biopolitical perspective,i.e.,to implement national politics over the population.Furthermore,the author reconstructs the logic of such biopolitical populism with the example of Poland,and as a consequence,the program of the“Law and Justice Party(PiS)”,which,after coming to power in 2015,introduced a new policy of“legal populism”,closely related to the conservative“procreative policy”(prohibition of abortion),and the family-oriented economy(financial supplement for each family for the second child,the so-called“500 plus”program).展开更多
Populism in Western democracies is on the rise.What was once conf ined to outliers and extreme political parties is now tearing away into the whole political system.Inflammatory speeches and critics of so-called'f...Populism in Western democracies is on the rise.What was once conf ined to outliers and extreme political parties is now tearing away into the whole political system.Inflammatory speeches and critics of so-called'fake news'made by展开更多
2017 is an election year for Europe,also a year on which hinges the destiny of Europe.In view of the general rise of right-wing populist parties in the EU,there have been concerns if another'black swan'would f...2017 is an election year for Europe,also a year on which hinges the destiny of Europe.In view of the general rise of right-wing populist parties in the EU,there have been concerns if another'black swan'would fly out of the general elections of the Netherland,France and Germany.To date,the Dutch and French展开更多
In recent years,right-wing populism has profoundly influenced the United States'political ecology.Centered on the populist ideology and President Donald Trump's"Make America Great Again"(MAGA)politic...In recent years,right-wing populism has profoundly influenced the United States'political ecology.Centered on the populist ideology and President Donald Trump's"Make America Great Again"(MAGA)political movement,it is evolving into the core driving force reshaping America's political landscape and impacting the global political and economic order.展开更多
In the last three decades, the rise of a populist challenge to the liberal political mainstream exposed how shallow the supposed victory of global liberalism was, even in its heartlands in Europe and North America. Ex...In the last three decades, the rise of a populist challenge to the liberal political mainstream exposed how shallow the supposed victory of global liberalism was, even in its heartlands in Europe and North America. Exclusive nationalism and nativism, identity politics, critiques of globaiisation and internationalism, and calls for democratic re-empowerment of the demos have converged politically on a new locus of inflated territorial, indeed ＇border＇ sovereignty, aligning the caU of ＇taking back control＇ on behalf of a radically re-defined community （＇we＇） with a defensive re-territorialisation of power along existing fault lines of nation-statism. In this paper, I argue that the very same call has become the new common political denominator for all populist platforms and parties across Europe. I argue that populists across the conventional left-fight divide have deployed a rigidly territo- rialised concept of popular sovereignty in order to bestow intellectual coherence and communicative power to the otherwise disparate strands of their anti-utopian cri- tiques of globalisation. In spite of significant ideological differences between so- called fight- and left-wing populism, in the short-term the two populist projects have sought to stage their performances of sovereigntism on, behind or inside the borders of the existing nation-states.展开更多
The three Baltic states of Estonia, Latvia and Lithuania make for interesting comparative case studies in the rise of contemporary populism in Europe. All three countries share a similar modem history, democratic poli...The three Baltic states of Estonia, Latvia and Lithuania make for interesting comparative case studies in the rise of contemporary populism in Europe. All three countries share a similar modem history, democratic political system, level of economic development and are in the same western-oriented regional clubs （NATO, European Union, OSCE, European Council and, in the case of Estonia and Latvia, OECD, etc.）. However, they do differ in the extent to which populism has played a role in their national politics. Populism has played a marginal role in Estonian politics, but has long been central to the Latvian party system and influential in Lithuanian politics. This article tackles two key issues in the study of populism. First, it focuses on political party institutionalisation as the key variable in explaining the differing impact of populist political parties across the Baltic states. It examines and explains the higher turnover of political party creation and destruction in Latvia and, to a lesser extent, Lithuania and argues that institutions--and par- ticularly the laws that frame party organisations and participation in elections-- create political opportunities for populist parties. The second part of the paper considers the different types of populist parties to have emerged in the Baltic states in recent decades. While previous studies of populism in the Baltic states （such as Auers and Kasekamp in J Contemp Eur Stud 17（2）：241-254, 2009; Auers and Kasekamp, in： Wodak et al （eds） Right wing populism across/beyond Europe, Bloomsbury Academic Press, London 2013） have explicitly focused on Radical Right Populist parties, this article additionally identifies a number of parties in the region that are not explicitly radical right, but are certainly populist.展开更多
In this paper,we establish and study a single-species logistic model with impulsive age-selective harvesting.First,we prove the ultimate boundedness of the solutions of the system.Then,we obtain conditions for the asy...In this paper,we establish and study a single-species logistic model with impulsive age-selective harvesting.First,we prove the ultimate boundedness of the solutions of the system.Then,we obtain conditions for the asymptotic stability of the trivial solution and the positive periodic solution.Finally,numerical simulations are presented to validate our results.Our results show that age-selective harvesting is more conducive to sustainable population survival than non-age-selective harvesting.展开更多
Populism combines the following characteristics:a rejection of economic policies linked to globalization;a condemnation of political and economic elites perceived as allied,directly or indirectly,to globalization poli...Populism combines the following characteristics:a rejection of economic policies linked to globalization;a condemnation of political and economic elites perceived as allied,directly or indirectly,to globalization policies;a nationalist conception of the national interest;a mistrust of immigration,seen as a threat to identity;as for populism’s supporters,a rather popular sociological profile,and an electoral profile that tends toward the“hard right”(“droite dure”),without ruling out bridges to the“hard left”(“gauche dure”).Having said this,I propose to defend three theses:populism is not the solution to the problems of the countries where it is developing,whether in France,the United States or elsewhere;it would be dangerous,however,to ignore the crises of which populism is the product;it is essential to take the measure of the problems that favor its emergence and to try to provide answers to them.展开更多
The rapidly aging population directly contributes to the increasing cases of neurological disorders.Due to the chronic progressive nature of neurodegeneration,numerous neurological conditions are considered“multifact...The rapidly aging population directly contributes to the increasing cases of neurological disorders.Due to the chronic progressive nature of neurodegeneration,numerous neurological conditions are considered“multifactorial”with systemic metabolic alterations.Even so,treatments for neurological disorders have remained unchanged for the past decades.Recently,metabolic drugs such as metformin and glucagon-like peptide 1 agonists have demonstrated promising health outcomes for neurodegeneration.展开更多
BACKGROUND Perioperative anesthesia management of obese patients presents significant challenges as traditional total body weight-based dosing fails to achieve optimal anesthetic effects due to altered pharmacokinetic...BACKGROUND Perioperative anesthesia management of obese patients presents significant challenges as traditional total body weight-based dosing fails to achieve optimal anesthetic effects due to altered pharmacokinetic characteristics including abnormal drug distribution and clearance.Rocuronium exhibits markedly different distribution patterns in obese patients,with conventional weight correction methods inadequately addressing individual muscle mass variations that critically influence drug distribution.AIM To investigate the quantitative relationship between skeletal muscle index(SMI)and rocuronium distribution volume in obese colorectal cancer patients,establish a population pharmacokinetic model,and develop individualized dosing strategies based on muscle mass.METHODS A retrospective cohort study was conducted,including 100 obese patients(body mass index≥30 kg/m^(2))who underwent elective radical colorectal cancer surgery at our hospital from June 2023 to January 2025.Skeletal muscle mass was measured using InBody 260 body composition analyzer and SMI was calculated to assess muscle mass,with male SMI<7.0 kg/m^(2) and female SMI<5.7 kg/m^(2)as diagnostic criteria for sarcopenia.Plasma rocuronium concentrations were detected by liquid chromatography-tandem mass spectrometry/mass spectrometry,and nonlinear mixed-effect modeling was used to establish population pharmacokinetic modeling.Stepwise regression was used to screen covariates,and dosing regimens were optimized through Monte Carlo simulation.The primary endpoint was targeted plasma concentration achievement rate,and the secondary endpoint was postoperative residual muscle relaxation incidence.RESULTS Among 100 patients,35(35.0%)had sarcopenia and 65(65.0%)did not.Patients in the sarcopenia group were older(64.1±9.8 years vs 54.2±10.9 years,P<0.001)and had significantly lower SMI(6.2±0.8 kg/m^(2)vs 8.4±1.2 kg/m^(2),P<0.001).SMI showed strong positive correlation with rocuronium steady-state distribution volume(r=0.718,P<0.001)and moderate negative correlation with clearance(r=-0.502,P<0.001).A two-compartment population pharmacokinetic model was successfully established,with SMI being the most important covariate affecting central compartment distribution volume(△OFV=-41.2,P<0.001).Model validation showed bootstrap successful convergence rate of 92.3%,and 92.1%of observed values fell within prediction intervals in predicted concentration versus predicted concentration.The SMI-based individualized dosing regimen improved target exposure achievement rate from 82.0%in traditional regimen to 93.5%(P=0.009),and reduced postoperative residual muscle relaxation incidence from 13.0%to 3.5%(P=0.018).The sarcopenia group showed the most significant improvement in achievement rate,from 71.4%to 93.8%(P=0.017).CONCLUSION SMI shows strong correlation with rocuronium distribution volume in obese colorectal cancer patients and is a key factor affecting drug distribution.SMI-based individualized dosing strategies can significantly improve target exposure achievement rate and reduce postoperative residual muscle relaxation incidence,providing scientific evidence for precision anesthesia management in obese patients.展开更多
To gain an in-depth understanding of China’s urban labor market,the Institute of Population and Labor Economics at the Chinese Academy of Social Sciences(IPLE-CASS)conducted the fifth wave of the China Urban Labor Su...To gain an in-depth understanding of China’s urban labor market,the Institute of Population and Labor Economics at the Chinese Academy of Social Sciences(IPLE-CASS)conducted the fifth wave of the China Urban Labor Survey in 2023,which covers eight major representative cities.The survey collected 9,122 household questionnaires and 26,145 individual questionnaires from 381 neighborhood committees.Based on this data,the report systematically analyzes employment,wages,educational attainment,and social security among China’s urban workforce.Key findings include an inverted U-shaped age pattern of labor force participation,with a widening gender gap after childbearing age.Additionally,job search methods combine market-based channels with traditional social networks.Notably,the gender wage gap persists and widens over the life cycle,while employed women now have higher average years of schooling than men.Rural-to-urban migrants show higher labor force participation rates but remain disadvantaged in wages,education,and social security coverage.Thus,this survey provides a comprehensive picture of the structural characteristics and challenges of China’s urban labor market,providing a solid data foundation for academic research and public policy design.展开更多
Wind-induced circulation is the main form of lake flow for shallow lakes and plays an important role in algae population distribution.This study constructed a three-dimensional hydrodynamic model(EFDC)of the plateau l...Wind-induced circulation is the main form of lake flow for shallow lakes and plays an important role in algae population distribution.This study constructed a three-dimensional hydrodynamic model(EFDC)of the plateau lake Erhai,China using accuracy wind field observation,runoff data and monthly algae data during 2022–2023.The model successfully reproduced the circulation characteristics of Erhai under prevailing wind directions.The results showed that the lake flow velocity in Lake Erhai is higher in winter than in summer,with lower velocities near shore particularly in the northern and central parts of the lake.There is a negative correlation between algal biomass and flow velocity(FV)in different zones,with lower FV favoring the accumulation of algal biomass,particularly for Microcystis,Dolichospermum,and Peridinium.Additionally,due to buoyancy,cyanobacteria are highly affected by wind direction and tend to accumulate in downwind regions of the prevailing wind direction.This study demonstrates that wind-induced circulation is a crucial factor affecting the spatial distribution of dominant algae populations in shallow plateau lakes with weak hydrodynamic force.Further,the risk of bloom occurrence in Lake Erhai will be higher due to the background of global climate change and the lake’s wind speed decline.In conclusion,we suggest implementing targeted zoning measures to control algal blooms and establishing stricter regulations for nitrogen and phosphorus control to counterbalance the promotion of algal bloom accumulation in low-velocity zones caused by reduced wind speed.展开更多
Elk are seen at the Tian’ezhou National Nature Reserve for Elk in Shishou,Hubei Province,on 27 November 2025.The reserve’s elk population has risen from just 64 in the 1990s to more than 4,500 today.
Objective:To investigate the sterilizing potential of zinc gluconate,calcium chloride(CaCl_(2))and cadmium chloride(CdCl_(2))following a single intratesticular administration in adult male rats.Methods:60 adult male W...Objective:To investigate the sterilizing potential of zinc gluconate,calcium chloride(CaCl_(2))and cadmium chloride(CdCl_(2))following a single intratesticular administration in adult male rats.Methods:60 adult male Wistar albino rats(Rattus norvegicus)weighing 160-200 g and aged 5-6 months randomly received a single intratesticular injection of normal saline(Group A),zinc gluconate 13.3 mg/mL plus L-Arginine(Group B),20%CaCl_(2)(Group C),and CdCl_(2)0.5 mg/kg body weight plus ethylenediaminetetraacetic acid(EDTA)(Group D),respectively,along the entire route from the caudoventral aspect of each testis.They were euthanized up to 180 days to evaluate reproductive tract toxicology.Results:The reproductive organ weights were markedly reduced,with testes severely atrophied in group B,pea-sized and stony hard in group C,and moderately reduced in group D.Azoospermia was evident in groups B and C,while sperm concentration was reduced to<1 million/mL with zero sperm motility in group D.Rats of groups B and C failed to show mounting and copulatory behaviour.A completely disorganized mesh of cellular elements was observed in the seminiferous tubules of group B,while pyknotic germ cell and arrest of spermatogenesis,exfoliated germ cells,occasional syncytial bodies and smaller Leydig cells were evident in groups C and D.Significantly reduced testosterone levels,increased luteinizing hormone(LH)and follicle-stimulating hormone(FSH)levels,returned to normal after 90 days in group D.Conclusions:Zinc gluconate and CaCl_(2)injections severely affected the reproductive organs and libido and rats treated with CdCl_(2)exhibited diminished spermatogenesis with normal libido.Thus,the need-based selection of intratesticular agents should consider their distinct effects on spermatogenesis,libido,and hormonal balance for achieving targeted sterilization outcomes.展开更多
Neurodegenerative diseases account for a large and increasing health and economic burden worldwide.With an increasingly aged population,this burden is set to increase.Optic neuropathies make up a large proportion of n...Neurodegenerative diseases account for a large and increasing health and economic burden worldwide.With an increasingly aged population,this burden is set to increase.Optic neuropathies make up a large proportion of neurodegenerative diseases with glaucoma being highly prevalent.Glaucoma is characterized by the progressive dysfunction and loss of retinal ganglion cells and their axons which make up the optic nerve.It is the leading cause of irreversible vision loss and affects an estimated 80 million people.The mammalian central nervous system is non-regenerative and,once lost or injured,retinal ganglion cells cannot regenerate an axon into the optic nerve under basal conditions.Thus,strategies that provide neuroprotection to stressed,dysfunctional,or dying retinal ganglion cells are likely to be of high therapeutic and translational value.Advancing age,genetics,and elevated intraocular pressure are all major risk factors for glaucoma,however,all clinically available glaucoma treatments focus on intraocular pressure management and do not directly address the neurodegenerative component of glaucoma.展开更多
The rise of the aging population parallels the rapidly increasing cases of neurological disorders. This puts pressure on scientists and physicians to find novel methods that can prevent and treat neurodegeneration. Th...The rise of the aging population parallels the rapidly increasing cases of neurological disorders. This puts pressure on scientists and physicians to find novel methods that can prevent and treat neurodegeneration. The brain is made up of a complex network of different cell types that work in tandem to maintain systemic homeostasis.展开更多
BACKGROUND In an era leaning toward a personalized alignment of total knee arthroplasty,coronal plane alignment of the knee(CPAK)phenotypes for each population are studied;furthermore,other possible variables affectin...BACKGROUND In an era leaning toward a personalized alignment of total knee arthroplasty,coronal plane alignment of the knee(CPAK)phenotypes for each population are studied;furthermore,other possible variables affecting the alignment,such as ankle joint alignment,should be considered.AIM To determine CPAK distribution in the North African(Egyptian)population with knee osteoarthritis and to assess ankle joint line orientation(AJLO)adaptations across different CPAK types.METHODS A cross-sectional study was conducted on patients with primary knee osteoarthritis and normal ankle joints.Radiographic parameters included the mechanical lateral distal femoral angle,medial proximal tibial angle,and the derived calculations of joint line obliquity(JLO)and arithmetic hip-knee-ankle angle(aHKA).The tibial plafond horizontal angle(TPHA)was used for AJLO assessment,where 0°is neutral(type N),<0°is varus(type A),and>0°is valgus(type B).The nine CPAK types were further divided into 27 subtypes after incorporating the three AJLO types.RESULTS A total of 527 patients(1054 knees)were included for CPAK classification,and 435 patients(870 knees and ankles)for AJLO assessment.The mean age was 57.2±7.8 years,with 79.5%females.Most knees(76.4%)demonstrated varus alignment(mean aHKA was-5.51°±4.84°)and apex distal JLO(55.3%)(mean JLO was 176.43°±4.53°).CPAK types I(44.3%),IV(28.6%),and II(10%)were the most common.Regarding AJLO,70.2%of ankles exhibited varus orientation(mean TPHA was-5.21°±6.45°).The most frequent combined subtypes were CPAK type I-A(33.7%),IV-A(21.5%),and I-N(6.9%).A significant positive correlation was found between the TPHA and aHKA(r=0.40,P<0.001).CONCLUSION In this North African cohort,varus knee alignment with apex distal JLO and varus AJLO predominated.CPAK types I,IV,and II were the most common types,while subtypes I-A,IV-A,and I-N were commonly occurring after incorporating AJLO types;furthermore,the AJLO was significantly correlated to aHKA.展开更多
文摘Social sciences positioned populism as a strategy to secure power/strength, a genuine political way, but besides it is positioned as an ideology, which divides society into two homogenous, antagonistic groups, brings society and elites face to face. Furthermore it is defined, as an ideology that wants politics to represent the society＇s general will. It is accepted that media and its production ＂logic＂ provides appropriate tools for populism development. In Turkey, which is governed by neoconservative and neo-liberal power, media populism has been the most used political communication strategy in recent years. Communication strategies, when there is a need to arouse and direct interest of the public opinion and for agenda setting processes; complexity, reduction, personalization, accusation, sentimentalizing, targeting, dramatization, alienation and creation of pseudo events, are frequently used. Most of the political actors appeal to media populism when they need to lean on to the society, disseminate the charismatic leader discourse, reduce the value of the discourses belonging to opponents, prove that they are representing the common goods and benefits. This study relates to direct-indirect practices of government＇s populism strategies. Within this context, creating legitimacy on political power by media populism in Turkey is assumed to be the most powerful method.
文摘A potential global power transition characterized by emerging economies of BRICS where China is the likely leading contender against the United States as the only global hegemon seems inevitable.The increasingly multipolar world is evidenced by the attention given to right-wing populism in Europe and USA attributed to China’s aggressive approach to international trade through its stealth entry and subsequent investments in global political-economy.China’s presence in Africa and Trump’s America first policy’s attempt to open“new business frontiers”in emerging economies of Asia and Africa in order to contain Chinese influence and threat in global hegemony are interesting happenstances that require closer scrutiny.Kenya,the biggest economy in East Africa,which is among the fastest growing regions globally,is the gateway to the East African Common Market.Historically,Kenya has a policy of non-alignment in international relations making it possible to receive FDI from both China and the US but with highly contested elections.Therefore,Kenya presents a perfect laboratory for examining the emerging power-shift in global political-economy as the country grapples with traditionally chaotic electoral power transitions and the two biggest economies in the world compete for business in Nairobi.The 2017 elections not only betrayed the international community’s commitment to Western values of human rights and democracy,but also revealed the challenges of governance in post-World War II global liberalism characterized by sophisticated media institutional spaces.
文摘Thanks to globalization and the emergence of the digital,capitalism progressively arrives to the stage of neoliberal financial hegemony. Therefore,in Europe today,Marxism remains powerful only in the form of leftist populism among the"radical left",as social-democrats and socialists have been largely absorbed by the right. However,because the struggle for hegemony is not only a binary relationship but also a triangular relationship,the only conceivable emancipation strategy is the old Marxist one,which is both dual,popular class against ruling class,and triangular,between three social forces (plus the competent). In this way,the popular class can access itself competence-power by associating with the competent and putting them under its own hegemony.
文摘In the presented paper,the author starts with diagnosing the state of research on populism and biopolitics simultaneously.The author states that most often in the literature the topic of populism(Laclau,Mouffe,Mudde,and Panizza)is considered separately from the problems related to biopolitics(Foucault,Negri,Agamben,and Esposito).The author would like to change this separation by bringing these two discourses closer together.The author’s main aim is to rethink populism from a biopolitical perspective,i.e.,to implement national politics over the population.Furthermore,the author reconstructs the logic of such biopolitical populism with the example of Poland,and as a consequence,the program of the“Law and Justice Party(PiS)”,which,after coming to power in 2015,introduced a new policy of“legal populism”,closely related to the conservative“procreative policy”(prohibition of abortion),and the family-oriented economy(financial supplement for each family for the second child,the so-called“500 plus”program).
文摘Populism in Western democracies is on the rise.What was once conf ined to outliers and extreme political parties is now tearing away into the whole political system.Inflammatory speeches and critics of so-called'fake news'made by
文摘2017 is an election year for Europe,also a year on which hinges the destiny of Europe.In view of the general rise of right-wing populist parties in the EU,there have been concerns if another'black swan'would fly out of the general elections of the Netherland,France and Germany.To date,the Dutch and French
文摘In recent years,right-wing populism has profoundly influenced the United States'political ecology.Centered on the populist ideology and President Donald Trump's"Make America Great Again"(MAGA)political movement,it is evolving into the core driving force reshaping America's political landscape and impacting the global political and economic order.
文摘In the last three decades, the rise of a populist challenge to the liberal political mainstream exposed how shallow the supposed victory of global liberalism was, even in its heartlands in Europe and North America. Exclusive nationalism and nativism, identity politics, critiques of globaiisation and internationalism, and calls for democratic re-empowerment of the demos have converged politically on a new locus of inflated territorial, indeed ＇border＇ sovereignty, aligning the caU of ＇taking back control＇ on behalf of a radically re-defined community （＇we＇） with a defensive re-territorialisation of power along existing fault lines of nation-statism. In this paper, I argue that the very same call has become the new common political denominator for all populist platforms and parties across Europe. I argue that populists across the conventional left-fight divide have deployed a rigidly territo- rialised concept of popular sovereignty in order to bestow intellectual coherence and communicative power to the otherwise disparate strands of their anti-utopian cri- tiques of globalisation. In spite of significant ideological differences between so- called fight- and left-wing populism, in the short-term the two populist projects have sought to stage their performances of sovereigntism on, behind or inside the borders of the existing nation-states.
文摘The three Baltic states of Estonia, Latvia and Lithuania make for interesting comparative case studies in the rise of contemporary populism in Europe. All three countries share a similar modem history, democratic political system, level of economic development and are in the same western-oriented regional clubs （NATO, European Union, OSCE, European Council and, in the case of Estonia and Latvia, OECD, etc.）. However, they do differ in the extent to which populism has played a role in their national politics. Populism has played a marginal role in Estonian politics, but has long been central to the Latvian party system and influential in Lithuanian politics. This article tackles two key issues in the study of populism. First, it focuses on political party institutionalisation as the key variable in explaining the differing impact of populist political parties across the Baltic states. It examines and explains the higher turnover of political party creation and destruction in Latvia and, to a lesser extent, Lithuania and argues that institutions--and par- ticularly the laws that frame party organisations and participation in elections-- create political opportunities for populist parties. The second part of the paper considers the different types of populist parties to have emerged in the Baltic states in recent decades. While previous studies of populism in the Baltic states （such as Auers and Kasekamp in J Contemp Eur Stud 17（2）：241-254, 2009; Auers and Kasekamp, in： Wodak et al （eds） Right wing populism across/beyond Europe, Bloomsbury Academic Press, London 2013） have explicitly focused on Radical Right Populist parties, this article additionally identifies a number of parties in the region that are not explicitly radical right, but are certainly populist.
基金Supported by the National Natural Science Foundation of China(12261018)Universities Key Laboratory of Mathematical Modeling and Data Mining in Guizhou Province(2023013)。
文摘In this paper,we establish and study a single-species logistic model with impulsive age-selective harvesting.First,we prove the ultimate boundedness of the solutions of the system.Then,we obtain conditions for the asymptotic stability of the trivial solution and the positive periodic solution.Finally,numerical simulations are presented to validate our results.Our results show that age-selective harvesting is more conducive to sustainable population survival than non-age-selective harvesting.
文摘Populism combines the following characteristics:a rejection of economic policies linked to globalization;a condemnation of political and economic elites perceived as allied,directly or indirectly,to globalization policies;a nationalist conception of the national interest;a mistrust of immigration,seen as a threat to identity;as for populism’s supporters,a rather popular sociological profile,and an electoral profile that tends toward the“hard right”(“droite dure”),without ruling out bridges to the“hard left”(“gauche dure”).Having said this,I propose to defend three theses:populism is not the solution to the problems of the countries where it is developing,whether in France,the United States or elsewhere;it would be dangerous,however,to ignore the crises of which populism is the product;it is essential to take the measure of the problems that favor its emergence and to try to provide answers to them.
文摘The rapidly aging population directly contributes to the increasing cases of neurological disorders.Due to the chronic progressive nature of neurodegeneration,numerous neurological conditions are considered“multifactorial”with systemic metabolic alterations.Even so,treatments for neurological disorders have remained unchanged for the past decades.Recently,metabolic drugs such as metformin and glucagon-like peptide 1 agonists have demonstrated promising health outcomes for neurodegeneration.
文摘BACKGROUND Perioperative anesthesia management of obese patients presents significant challenges as traditional total body weight-based dosing fails to achieve optimal anesthetic effects due to altered pharmacokinetic characteristics including abnormal drug distribution and clearance.Rocuronium exhibits markedly different distribution patterns in obese patients,with conventional weight correction methods inadequately addressing individual muscle mass variations that critically influence drug distribution.AIM To investigate the quantitative relationship between skeletal muscle index(SMI)and rocuronium distribution volume in obese colorectal cancer patients,establish a population pharmacokinetic model,and develop individualized dosing strategies based on muscle mass.METHODS A retrospective cohort study was conducted,including 100 obese patients(body mass index≥30 kg/m^(2))who underwent elective radical colorectal cancer surgery at our hospital from June 2023 to January 2025.Skeletal muscle mass was measured using InBody 260 body composition analyzer and SMI was calculated to assess muscle mass,with male SMI<7.0 kg/m^(2) and female SMI<5.7 kg/m^(2)as diagnostic criteria for sarcopenia.Plasma rocuronium concentrations were detected by liquid chromatography-tandem mass spectrometry/mass spectrometry,and nonlinear mixed-effect modeling was used to establish population pharmacokinetic modeling.Stepwise regression was used to screen covariates,and dosing regimens were optimized through Monte Carlo simulation.The primary endpoint was targeted plasma concentration achievement rate,and the secondary endpoint was postoperative residual muscle relaxation incidence.RESULTS Among 100 patients,35(35.0%)had sarcopenia and 65(65.0%)did not.Patients in the sarcopenia group were older(64.1±9.8 years vs 54.2±10.9 years,P<0.001)and had significantly lower SMI(6.2±0.8 kg/m^(2)vs 8.4±1.2 kg/m^(2),P<0.001).SMI showed strong positive correlation with rocuronium steady-state distribution volume(r=0.718,P<0.001)and moderate negative correlation with clearance(r=-0.502,P<0.001).A two-compartment population pharmacokinetic model was successfully established,with SMI being the most important covariate affecting central compartment distribution volume(△OFV=-41.2,P<0.001).Model validation showed bootstrap successful convergence rate of 92.3%,and 92.1%of observed values fell within prediction intervals in predicted concentration versus predicted concentration.The SMI-based individualized dosing regimen improved target exposure achievement rate from 82.0%in traditional regimen to 93.5%(P=0.009),and reduced postoperative residual muscle relaxation incidence from 13.0%to 3.5%(P=0.018).The sarcopenia group showed the most significant improvement in achievement rate,from 71.4%to 93.8%(P=0.017).CONCLUSION SMI shows strong correlation with rocuronium distribution volume in obese colorectal cancer patients and is a key factor affecting drug distribution.SMI-based individualized dosing strategies can significantly improve target exposure achievement rate and reduce postoperative residual muscle relaxation incidence,providing scientific evidence for precision anesthesia management in obese patients.
基金supported by the Special Project of the National Natural Science Foundation of China(NSFC)“The Uniqueness of China’s Demographic Transition,Its Economic Impact,and Policy Implications”(Grant No.72141310)the Major Economic and Social Survey Project of the Chinese Academy of Social Sciences(CASS)“China Urban Labor Survey”(Grant No.GQDC2023022)the Comprehensive Grant of CASS Affiliated Institute Laboratories“Population Simulation and Employment Monitoring Laboratory”(Grant No.2024SYZH008).
文摘To gain an in-depth understanding of China’s urban labor market,the Institute of Population and Labor Economics at the Chinese Academy of Social Sciences(IPLE-CASS)conducted the fifth wave of the China Urban Labor Survey in 2023,which covers eight major representative cities.The survey collected 9,122 household questionnaires and 26,145 individual questionnaires from 381 neighborhood committees.Based on this data,the report systematically analyzes employment,wages,educational attainment,and social security among China’s urban workforce.Key findings include an inverted U-shaped age pattern of labor force participation,with a widening gender gap after childbearing age.Additionally,job search methods combine market-based channels with traditional social networks.Notably,the gender wage gap persists and widens over the life cycle,while employed women now have higher average years of schooling than men.Rural-to-urban migrants show higher labor force participation rates but remain disadvantaged in wages,education,and social security coverage.Thus,this survey provides a comprehensive picture of the structural characteristics and challenges of China’s urban labor market,providing a solid data foundation for academic research and public policy design.
基金supported by the Open Research Fund of Key Laboratory for Lake Pollution Control of the Ministry of Ecology and Environment(No.2024HPYKFZD04)the Fundamental Research Funds for the Central Publicinterest Scientific Institution(No.2025YSKY-04)the National Natural Science Foundation of China(Nos.U1902207 and 42207265).
文摘Wind-induced circulation is the main form of lake flow for shallow lakes and plays an important role in algae population distribution.This study constructed a three-dimensional hydrodynamic model(EFDC)of the plateau lake Erhai,China using accuracy wind field observation,runoff data and monthly algae data during 2022–2023.The model successfully reproduced the circulation characteristics of Erhai under prevailing wind directions.The results showed that the lake flow velocity in Lake Erhai is higher in winter than in summer,with lower velocities near shore particularly in the northern and central parts of the lake.There is a negative correlation between algal biomass and flow velocity(FV)in different zones,with lower FV favoring the accumulation of algal biomass,particularly for Microcystis,Dolichospermum,and Peridinium.Additionally,due to buoyancy,cyanobacteria are highly affected by wind direction and tend to accumulate in downwind regions of the prevailing wind direction.This study demonstrates that wind-induced circulation is a crucial factor affecting the spatial distribution of dominant algae populations in shallow plateau lakes with weak hydrodynamic force.Further,the risk of bloom occurrence in Lake Erhai will be higher due to the background of global climate change and the lake’s wind speed decline.In conclusion,we suggest implementing targeted zoning measures to control algal blooms and establishing stricter regulations for nitrogen and phosphorus control to counterbalance the promotion of algal bloom accumulation in low-velocity zones caused by reduced wind speed.
文摘Elk are seen at the Tian’ezhou National Nature Reserve for Elk in Shishou,Hubei Province,on 27 November 2025.The reserve’s elk population has risen from just 64 in the 1990s to more than 4,500 today.
基金financially assisted to Timanshi Chansoriya of the fellowship grant of UGC-NFPwD,New Delhi sanctioned vide UGC F.No.01-01/2019-Sch dated 06.11.2020(Serial No.352 ID:NFPWD-2018-20-UTP-6522).
文摘Objective:To investigate the sterilizing potential of zinc gluconate,calcium chloride(CaCl_(2))and cadmium chloride(CdCl_(2))following a single intratesticular administration in adult male rats.Methods:60 adult male Wistar albino rats(Rattus norvegicus)weighing 160-200 g and aged 5-6 months randomly received a single intratesticular injection of normal saline(Group A),zinc gluconate 13.3 mg/mL plus L-Arginine(Group B),20%CaCl_(2)(Group C),and CdCl_(2)0.5 mg/kg body weight plus ethylenediaminetetraacetic acid(EDTA)(Group D),respectively,along the entire route from the caudoventral aspect of each testis.They were euthanized up to 180 days to evaluate reproductive tract toxicology.Results:The reproductive organ weights were markedly reduced,with testes severely atrophied in group B,pea-sized and stony hard in group C,and moderately reduced in group D.Azoospermia was evident in groups B and C,while sperm concentration was reduced to<1 million/mL with zero sperm motility in group D.Rats of groups B and C failed to show mounting and copulatory behaviour.A completely disorganized mesh of cellular elements was observed in the seminiferous tubules of group B,while pyknotic germ cell and arrest of spermatogenesis,exfoliated germ cells,occasional syncytial bodies and smaller Leydig cells were evident in groups C and D.Significantly reduced testosterone levels,increased luteinizing hormone(LH)and follicle-stimulating hormone(FSH)levels,returned to normal after 90 days in group D.Conclusions:Zinc gluconate and CaCl_(2)injections severely affected the reproductive organs and libido and rats treated with CdCl_(2)exhibited diminished spermatogenesis with normal libido.Thus,the need-based selection of intratesticular agents should consider their distinct effects on spermatogenesis,libido,and hormonal balance for achieving targeted sterilization outcomes.
基金supported by St.Erik Eye Hospital philanthropic donations,Vetenskapsrådet 2022-00799(to PAW).
文摘Neurodegenerative diseases account for a large and increasing health and economic burden worldwide.With an increasingly aged population,this burden is set to increase.Optic neuropathies make up a large proportion of neurodegenerative diseases with glaucoma being highly prevalent.Glaucoma is characterized by the progressive dysfunction and loss of retinal ganglion cells and their axons which make up the optic nerve.It is the leading cause of irreversible vision loss and affects an estimated 80 million people.The mammalian central nervous system is non-regenerative and,once lost or injured,retinal ganglion cells cannot regenerate an axon into the optic nerve under basal conditions.Thus,strategies that provide neuroprotection to stressed,dysfunctional,or dying retinal ganglion cells are likely to be of high therapeutic and translational value.Advancing age,genetics,and elevated intraocular pressure are all major risk factors for glaucoma,however,all clinically available glaucoma treatments focus on intraocular pressure management and do not directly address the neurodegenerative component of glaucoma.
文摘The rise of the aging population parallels the rapidly increasing cases of neurological disorders. This puts pressure on scientists and physicians to find novel methods that can prevent and treat neurodegeneration. The brain is made up of a complex network of different cell types that work in tandem to maintain systemic homeostasis.
基金approved by Institutional Review Board of Faculty of Medicine in Assiut University,No.04-2024-300470.
文摘BACKGROUND In an era leaning toward a personalized alignment of total knee arthroplasty,coronal plane alignment of the knee(CPAK)phenotypes for each population are studied;furthermore,other possible variables affecting the alignment,such as ankle joint alignment,should be considered.AIM To determine CPAK distribution in the North African(Egyptian)population with knee osteoarthritis and to assess ankle joint line orientation(AJLO)adaptations across different CPAK types.METHODS A cross-sectional study was conducted on patients with primary knee osteoarthritis and normal ankle joints.Radiographic parameters included the mechanical lateral distal femoral angle,medial proximal tibial angle,and the derived calculations of joint line obliquity(JLO)and arithmetic hip-knee-ankle angle(aHKA).The tibial plafond horizontal angle(TPHA)was used for AJLO assessment,where 0°is neutral(type N),<0°is varus(type A),and>0°is valgus(type B).The nine CPAK types were further divided into 27 subtypes after incorporating the three AJLO types.RESULTS A total of 527 patients(1054 knees)were included for CPAK classification,and 435 patients(870 knees and ankles)for AJLO assessment.The mean age was 57.2±7.8 years,with 79.5%females.Most knees(76.4%)demonstrated varus alignment(mean aHKA was-5.51°±4.84°)and apex distal JLO(55.3%)(mean JLO was 176.43°±4.53°).CPAK types I(44.3%),IV(28.6%),and II(10%)were the most common.Regarding AJLO,70.2%of ankles exhibited varus orientation(mean TPHA was-5.21°±6.45°).The most frequent combined subtypes were CPAK type I-A(33.7%),IV-A(21.5%),and I-N(6.9%).A significant positive correlation was found between the TPHA and aHKA(r=0.40,P<0.001).CONCLUSION In this North African cohort,varus knee alignment with apex distal JLO and varus AJLO predominated.CPAK types I,IV,and II were the most common types,while subtypes I-A,IV-A,and I-N were commonly occurring after incorporating AJLO types;furthermore,the AJLO was significantly correlated to aHKA.
