Bacterial infections,as a global public health problem,are a serious threat to human life and health safety with the significant increase of antibiotic-resist ant bacteria.Polyoxometalates(POMs),with their unique stru...Bacterial infections,as a global public health problem,are a serious threat to human life and health safety with the significant increase of antibiotic-resist ant bacteria.Polyoxometalates(POMs),with their unique structure,and high biocompatibility and designability,have received widespread attention in the field of antimicrobials,showing great potential,which has led to the design of various strategies to fabricate POM-based composites with antimicrobial properties.In this paper,the preparation strategies based on the biological components of POMs and their organic derivatives are reviewed,and the latest progress in the design and preparation of various antimicrobial POM-based materials and the practical application of POM antibacterial materials in some fields are introduced in detail from four aspects:pure inorganic POMs,POM-based materials bound to organic small molecules,POM-based materials bound to organic biomolecules,and POM-based nanocomposites.In addition,the potential antimicrobial mechanisms of POMs are summarized,and the significant advantages of POMs in collaboration with antibiotics against drug-resistant bacteria are demonstrated.The limitations and prospects of current research are also discussed.It is hoped that this review can help researchers to keep abreast of the development of POM-based antimicrobial materials,thus promoting their development,application,and large-scale production.展开更多
The widespread application of phenolic substances in the field of food,medicine and industry,is harmful to the environment and human health.Therefore,it is very important to develop a con-venient and effective method ...The widespread application of phenolic substances in the field of food,medicine and industry,is harmful to the environment and human health.Therefore,it is very important to develop a con-venient and effective method to detect and degrade phenolic compounds.Herein,we report a new keggin-type polyoxometallate-based metal-organic complex self-assembled under solvothermal condition,{[Cu(dap)(3-PA)]4(SiW_(12)O_(40))(H_(2)O)_(2)}·2H_(2)O(1,dap=1,2-diaminopropane,3-HPA=3-pyridineacrylic acid).1 shows an interesting 1D ladder-like structure.As a bifunctional catalyst,1 can be employed as a colori-metric sensor toward phenol with the relatively low detection limit(LOD)of 0.36μmol/L(S/N=3)in the wide range(0.001-0.1 mmol/L).The title colorimetric sensor is applied to determine phenol in various water environment with good recoveries ranging from 95%-105%.In addition,1 also exhibits excellent photocatalytic degradation toward phenol under visible light with the highest removal efficiency at 96%for 100 min and wide pH universality.The selectivity,stability and reliability of the detection of 1 towards phenol,as well as the detection for 4-chlorophenol,o-cresol,4-nitrophenol and phloroglucinol were stud-ied.Furthermore,the photocatalytic reaction kinetics and the mechanisms of photodegradation of phenol were also investigated in detail.展开更多
基金financially supported by the Natural Science Foundation of China(No.21801153)the Natural Science Foundation of Shandong Province(No.ZR2023MB065)+2 种基金the Shandong Province Chinese Medicine Science and Technology Development Project(No.M-2022258)the Young Scientist Development Foundation of Shandong First Medical University(No.202201-002)the Academic Promotion Program of Shandong First Medical University(No.2019LJ003)
文摘Bacterial infections,as a global public health problem,are a serious threat to human life and health safety with the significant increase of antibiotic-resist ant bacteria.Polyoxometalates(POMs),with their unique structure,and high biocompatibility and designability,have received widespread attention in the field of antimicrobials,showing great potential,which has led to the design of various strategies to fabricate POM-based composites with antimicrobial properties.In this paper,the preparation strategies based on the biological components of POMs and their organic derivatives are reviewed,and the latest progress in the design and preparation of various antimicrobial POM-based materials and the practical application of POM antibacterial materials in some fields are introduced in detail from four aspects:pure inorganic POMs,POM-based materials bound to organic small molecules,POM-based materials bound to organic biomolecules,and POM-based nanocomposites.In addition,the potential antimicrobial mechanisms of POMs are summarized,and the significant advantages of POMs in collaboration with antibiotics against drug-resistant bacteria are demonstrated.The limitations and prospects of current research are also discussed.It is hoped that this review can help researchers to keep abreast of the development of POM-based antimicrobial materials,thus promoting their development,application,and large-scale production.
基金supported by the National Natural Science Foundation of China(NSFC,Nos.21901018,21971024,22271021)the Natural Science Foundation and Education Department of Liaoning province(Nos.2022-MS-373,2021-MS-312,LJ2020008).
文摘The widespread application of phenolic substances in the field of food,medicine and industry,is harmful to the environment and human health.Therefore,it is very important to develop a con-venient and effective method to detect and degrade phenolic compounds.Herein,we report a new keggin-type polyoxometallate-based metal-organic complex self-assembled under solvothermal condition,{[Cu(dap)(3-PA)]4(SiW_(12)O_(40))(H_(2)O)_(2)}·2H_(2)O(1,dap=1,2-diaminopropane,3-HPA=3-pyridineacrylic acid).1 shows an interesting 1D ladder-like structure.As a bifunctional catalyst,1 can be employed as a colori-metric sensor toward phenol with the relatively low detection limit(LOD)of 0.36μmol/L(S/N=3)in the wide range(0.001-0.1 mmol/L).The title colorimetric sensor is applied to determine phenol in various water environment with good recoveries ranging from 95%-105%.In addition,1 also exhibits excellent photocatalytic degradation toward phenol under visible light with the highest removal efficiency at 96%for 100 min and wide pH universality.The selectivity,stability and reliability of the detection of 1 towards phenol,as well as the detection for 4-chlorophenol,o-cresol,4-nitrophenol and phloroglucinol were stud-ied.Furthermore,the photocatalytic reaction kinetics and the mechanisms of photodegradation of phenol were also investigated in detail.
