期刊文献+
共找到23,574篇文章
< 1 2 250 >
每页显示 20 50 100
哺乳动物细胞POLK、POLH、POLI基因对甲基硝基亚硝基胍的应答反应及其启动子区转录因子结合部位的生物信息学分析 被引量:2
1
作者 蒋余圣 钱羽力 余应年 《中国病理生理杂志》 CAS CSCD 北大核心 2006年第7期1249-1255,共7页
目的:观察甲基硝基亚硝基胍(MNNG)对培养细胞DNA聚合酶κ、η、ι编码基因表达的影响并用生物信息学方法预测它们的启动子区和启动子区中的转录因子结合部位。方法:利用半定量RT-PCR观察POLK、POLH、POLI基因表达改变。利用在线生物信... 目的:观察甲基硝基亚硝基胍(MNNG)对培养细胞DNA聚合酶κ、η、ι编码基因表达的影响并用生物信息学方法预测它们的启动子区和启动子区中的转录因子结合部位。方法:利用半定量RT-PCR观察POLK、POLH、POLI基因表达改变。利用在线生物信息学软件,确定它们的启动子区,然后,用转录因子预测软件并结合进化足迹法检出包括启动子区在内的3000bp碱基上游序列中的转录因子结合部位。结果:0.2μmol·L-1MNNG导致细胞POLH和POLI表达水平在处理后6-24h间逐渐上升,升高约1倍;而POLK则呈下降;通过转录因子预测软件分析,在POLK、H和I启动子区分别检出了384个、413个和689个推断的转录因子结合部位;通过进化足迹法分析有效地降低了假阳性率,推断的转录因子结合部位分别下降到158个、80个和40个。结论:低浓度MNNG导致POLH、POLI表达水平升高,而POLK表达水平降低;通过在线软件,我们成功地在POLK,POLH,POLI启动子区分别检出。158、80和40个推断的转录因子结合部位;进化足迹法分析能够有效降低预测软件的假阳性率。 展开更多
关键词 DNA聚合酶类 转录因子结合部位 基因 POLK 基因 POLH 基因 poli 甲硝基亚硝胍
暂未订购
THE TWENTY OF THE POLIS' AND THE DRERIAN PHYLAI
2
作者 Oliver Grote 《Journal of Ancient Civilizations》 2014年第1期63-76,共14页
There is a consensus among scholars of ancient Greek history that the phylê1was not only a functional unit belonging to political systems of Greek communities,but that it also played a decisive part in the singul... There is a consensus among scholars of ancient Greek history that the phylê1was not only a functional unit belonging to political systems of Greek communities,but that it also played a decisive part in the singular process known as the rise of the polis,i.e.the transformation from settlements into political communities of citizens.2Nevertheless,little attention has been paid to the concrete political function fulfilled by the phylai in particular poleis.Only the famous 展开更多
关键词 poliTICAL polis COUNCIL GREEK CONSENSUS ANCIENT SI
在线阅读 下载PDF
Antiulcerogenic Effect of Brazilian Propolis Formulation in Mice
3
作者 Niraldo Paulino Lucas Amorim Coutinho +3 位作者 Jose Reinaldo Coutinho Giselle Cunha Vilela Veroneide Pio da Silva Leandro Amarilis Scremin Paulino 《Pharmacology & Pharmacy》 2015年第12期580-588,共9页
Propolis is a natural resin used around the world to treatment of several diseases. We evaluated the effect of Brazilian propolis (P1) in guinea pig isolated trachea in vitro contracted with hista-mine, in paw oedema ... Propolis is a natural resin used around the world to treatment of several diseases. We evaluated the effect of Brazilian propolis (P1) in guinea pig isolated trachea in vitro contracted with hista-mine, in paw oedema induced by histamine in mice and anti-ulcerogenic effect of propolis formulation in mice. We used a P1 extract from South of Brazil to produce a formulation containing sodium bicarbonate and propolis dry extract (2%). In the guinea pig trachea Brazilian propolis extract (10 μg/mL) produced a non-significant inhibition in the cumulative response curve for histamine. However, the dose of 100 μg/mL shown had a significant inhibitory effect on the contraction induced by histamine (51% ± 5%). In the mouse paw oedema induced by intraplantar injection of histamine (50 μg/paw), the results showed that the treatment of the mice with P1 (10 or 100 mg/Kg (p.o) or 1 or 10 mg/Kg (i.p)), 0.5 h beforehand, significantly inhibited the paw oedema with maximal inhibition (MI) of 25% or 42% by p.o. route or 22% or 37% by i.p. route, respectively. Finally we have pre-treated mice with P1 formulation (20 mg/Kg or 40 mg/Kg, p.o, one time) or vehicle (powder) in animals submitted to diclofenac-induced ulcer, after 8 h P1 formulation inhibited of 43% or 83% of ulcers scores, respectively. Results showed that P1 formulation inhibited the ulcerogenic effect induced by diclofenac. Results suggested also, at least in part, the antiulcerogenic effect of formulation containing standardized extract of propolis can be due to the antagonistic action on the histaminergic system. 展开更多
关键词 PROpoliS FORMULATION ULCER STOMACH MICE Palavras Chaves: Própolis Formula??o Oral úlcera Est?mago Camundongo
暂未订购
Subsidy Policies on Wool Sheep and Cashmere Goat Industry at the Background of Sustainable Development
4
作者 Haiyan CHEN Haifeng XIAO 《Asian Agricultural Research》 2014年第4期10-13,18,共5页
Grassland ecological protection measures such as grazing prohibition and livestock changed traditional production mode of the cashmere goat industry,and exerted adverse influence on production of cashmere and income o... Grassland ecological protection measures such as grazing prohibition and livestock changed traditional production mode of the cashmere goat industry,and exerted adverse influence on production of cashmere and income of farmers and herdsmen.On the basis of the survey in Inner Mongolia,Xinjiang,Jilin,Liaoning,Shanxi,and Yunnan,this paper evaluated effect of subsidy policies on wool sheep and cashmere goat industry and present some existing problems in the implementation of these policies.Finally,it came up with following recommendations:strengthening cultivation and protection of wool sheep and cashmere goat varieties,increasing subsidy level of fine varieties and expanding coverage of subsidy policies,formulating wool sheep and cashmere price supportive measures,enhancing construction of wool sheep and cashmere goat sci-tech service system,and promoted standardized production of cashmere goat. 展开更多
关键词 WOOL SHEEP and CASHMERE GOAT INDUSTRY SUBSIDY poli
在线阅读 下载PDF
Dyke Swarms Florianópolis: Petrologic and Structural Aspects Related to Rifting Supercontinent Gondwana and Formation South Atlantic in the Santa Catarina of Island, Brazil
5
作者 Edison R.Tomazzoli Jean de B.Veronez 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2016年第S1期94-96,共3页
From a point of magmatic view,the rupturing Gondwana Supercontinent is registered on the South American shelf in continental flood basalts,mafic dyke swarms,basins rift and,to a lesser extent,by intrusions alkaline.Am... From a point of magmatic view,the rupturing Gondwana Supercontinent is registered on the South American shelf in continental flood basalts,mafic dyke swarms,basins rift and,to a lesser extent,by intrusions alkaline.Among those 展开更多
关键词 polis Petrologic and Structural Aspects Related to Rifting Supercontinent Gondwana and Formation South Atlantic in the Santa Catarina of Island Brazil Dyke Swarms Florian
在线阅读 下载PDF
意大利Poli公司的轮装制动盘
6
作者 祝华 《国外铁道车辆》 2005年第4期44-44,共1页
关键词 意大利 poli公司 扇块轮装制动盘 车辆工程 制动装备
在线阅读 下载PDF
A Comparative Assessment of the Surface Roughness of Thermoplastic Denture Base Resins Following Adjustment and Re-Polishing
7
作者 Shivaughn M. Marchan Anna Kay Bishop +2 位作者 William A. J. Smith Paul Seerattan David Hinds 《Open Journal of Stomatology》 2017年第4期250-263,共14页
Purpose: This study assessed the roughness of two injection-molded, thermoplastic materials used for denture bases compared with a polyamide material and compression molded Polymethylmethacrylate (PMMA) after the adju... Purpose: This study assessed the roughness of two injection-molded, thermoplastic materials used for denture bases compared with a polyamide material and compression molded Polymethylmethacrylate (PMMA) after the adjustment and re-polishing with either a laboratory protocol or a chair side protocol. Methods: Forty specimens, each of PMMA, Valplast, DuraFlex, Dura Cetal were fabricated and finished according to individual manufactures’ instructions. These materials were adjusted with tungsten carbide (TC) burs to mimic gross adjustments, and then re-polished either on a lathe or bonded silicon carbide (B-SC). Following instrumentation, the specimens were assessed using contact profilometry and scanning electron microscopy. Two-factor ANOVA was used to determine significant differences in mean surface roughness (Ra and Rmax), with included factors being material type and re-polishing regimen. Results: Mean Ra values ranged from 0.26 (DuraFlex control) to 1.82 (Valplast adjusted with TC burs). Mean Rmax values ranged from 1.88 (Dura Flex control) to 13.76 (Valplast adjusted with TC burs). Two-factor ANOVA revealed that interaction of both factors was significant (p Ra and Rmax. There was a statistically significant increase in both Ra (p Rmax (p < 0.05) for all material types following the gross adjustment. With the exception of DuraFlex, re-polishing of samples that were previously adjusted with TC burs, on the dental lathe produced surfaces that were comparable to control samples. Conclusion: Adjustment of DuraFlex should be kept to a minimum since the adjustment produced the significant surface detriment that could not be corrected with either of the polishing regimens. 展开更多
关键词 DuraFlex DuraCetal Valplast Poly METHYLMETHACRYLATE Surface ROUGHNESS
暂未订购
聚肌细胞(Poli,I:C)对迁延性、慢性乙型病毒性肝炎52例疗效观察(摘要)
8
作者 张玲霞 尤大栋 《北京医学》 CAS 1979年第2期114-114,共1页
为了探索对迁延性,慢性乙型病毒性肝炎(以下简称迁慢肝)的有效治疗,我院于1977年11月~1978年9月采用中国科学院遗传研究所、天津味精厂协作供药的干扰素诱导剂(聚肌胞)治疗迁肝37例,慢肝15例,共52例,取得一定疗效。全部病例诊断符合“... 为了探索对迁延性,慢性乙型病毒性肝炎(以下简称迁慢肝)的有效治疗,我院于1977年11月~1978年9月采用中国科学院遗传研究所、天津味精厂协作供药的干扰素诱导剂(聚肌胞)治疗迁肝37例,慢肝15例,共52例,取得一定疗效。全部病例诊断符合“病毒性肝炎防治方案”标准. 展开更多
关键词 慢性乙型病毒性肝炎 poli I 迁延性
原文传递
荷马时代的“polis” 被引量:9
9
作者 晏绍祥 《历史研究》 CSSCI 北大核心 2004年第2期145-159,共15页
荷马社会并非传统所说的血缘氏族部落 ,而是 polis。作为一种政治组织 ,它是以某一城市为中心、结合周围乡村形成的共同体。对于共同体 ,荷马英雄们大体认同 ;在其内部 ,公、私领域分明 ;集体行使权力的机构已经产生 ,军事制度已经发生... 荷马社会并非传统所说的血缘氏族部落 ,而是 polis。作为一种政治组织 ,它是以某一城市为中心、结合周围乡村形成的共同体。对于共同体 ,荷马英雄们大体认同 ;在其内部 ,公、私领域分明 ;集体行使权力的机构已经产生 ,军事制度已经发生变化 ,宗教权力已经世俗化 。 展开更多
关键词 荷马 polis 血缘氏族部落 军事制度 宗教权力 古典城邦制度
原文传递
海格立斯与polis渊源考 被引量:2
10
作者 隋竹丽 《世界宗教文化》 CSSCI 北大核心 2014年第6期99-103,共5页
Polis作为神权王权起源于克里特,由阿基里斯盾牌传承,由奥德修斯传回希腊大陆。荷马时代海伦代表公民权,polis公民社会理念,被海格立斯等英雄信仰传播,演变为普罗米修斯神话。多里斯人回归,创立了亚尔古船模式,但保留了王子人祭。提修... Polis作为神权王权起源于克里特,由阿基里斯盾牌传承,由奥德修斯传回希腊大陆。荷马时代海伦代表公民权,polis公民社会理念,被海格立斯等英雄信仰传播,演变为普罗米修斯神话。多里斯人回归,创立了亚尔古船模式,但保留了王子人祭。提修斯的雅典娜模式,取消了王子人祭,确立了公民神权的神圣地位。Polis是英雄净化了戈尔工,彻底清除专制王权,避免了英雄本性的历史结局。 展开更多
关键词 海格立斯 polis 神权王权 公民神权
原文传递
古希腊词polis的汉译探析
11
作者 李科 《时代人物》 2021年第31期0031-0032,共2页
Polis 是古希腊社会的一种政治组织,英译为city-state, 汉译为“城邦”。这些译名都算不上完全准确,因为在英语和汉语中都没有确切的对译词,城邦并不是城市也不能说就是一个国家,但是比起城市,一个城邦更像是一个国家。要得到polis确切... Polis 是古希腊社会的一种政治组织,英译为city-state, 汉译为“城邦”。这些译名都算不上完全准确,因为在英语和汉语中都没有确切的对译词,城邦并不是城市也不能说就是一个国家,但是比起城市,一个城邦更像是一个国家。要得到polis确切的翻译,对何为城邦,它对希腊人有何意义这样的问题如果缺乏明确的了解,就不能正确理解希腊历史,是不可能找到准确的译名的。 展开更多
关键词 polis 城邦 翻译
在线阅读 下载PDF
3D打印聚乳酸骨支架修复骨缺损 被引量:1
12
作者 杨凤丽 周朝 +4 位作者 熊伟 周宇翔 李登顺 王鑫 李展振 《中国组织工程研究》 北大核心 2026年第2期507-515,共9页
背景:3D打印的骨组织工程支架在骨缺损修复的研究和临床治疗中具有明显优势。聚乳酸作为3D打印骨支架的重要原料之一,在进行骨缺损修复时应用潜力巨大,但临床患者的骨缺损诱因不同,对聚乳酸骨支架的综合性能提出了不同要求。目的:对3D... 背景:3D打印的骨组织工程支架在骨缺损修复的研究和临床治疗中具有明显优势。聚乳酸作为3D打印骨支架的重要原料之一,在进行骨缺损修复时应用潜力巨大,但临床患者的骨缺损诱因不同,对聚乳酸骨支架的综合性能提出了不同要求。目的:对3D打印技术和聚乳酸支架的发展及支架在骨髓炎、骨肿瘤、骨坏死和骨质疏松等骨病环境下进行骨修复时所选用的设计策略进行归纳与综述。方法:从中国知网、万方、PubMed、Science Direct与Web of Science数据库中检索和筛选发表时间为1994-2024年的相关文献。英文检索词:“3D printing,Polylactic acid,Bone tissue engineering scaffold,Osteomyelitis,Bone tumor,Osteonecrosis,Osteoporosis,Bone defect”,中文检索词:“3D打印,聚乳酸,骨组织工程支架,骨髓炎,骨肿瘤,骨坏死,骨质疏松,骨缺损”,对筛选出的62篇文献进行系统归纳与分析。结果与结论:①聚乳酸因具有无毒性、可加工性强、生物相容性好以及能在人体环境中自我降解的特性,被认为是理想的人工骨支架设计原料。3D打印技术的应用使得聚乳酸骨支架能够满足仿生人工骨修复材料的多层多孔结构设计要求,并优化了力学性能,以更好地进行骨修复。②根据不同的骨病微环境,适时调整聚乳酸支架的功能设计对支架综合成骨效能的发挥十分重要。文章讨论了聚乳酸支架在骨髓炎、骨肿瘤、骨坏死和骨质疏松等骨病环境下的应用,强调了针对不同骨病所导致的骨缺损,合理把握骨病治疗与骨组织再生的时间节点的重要性。③尽管聚乳酸支架在骨修复中显示出潜力,但仍存在一些问题,如需要进一步优化支架的结构设计以适配新骨再生,增强支架的生物活性,并兼顾其他功能(如抗菌、抗肿瘤及抗骨质疏松等)以适应不同病理环境下骨组织修复的需求。 展开更多
关键词 3D打印 聚乳酸 骨组织工程支架 骨髓炎 骨肿瘤 骨坏死 骨质疏松 骨缺损
在线阅读 下载PDF
不同水平多不饱和脂肪酸的鳙肌肉转录组分析
13
作者 沈晓桔 王兰梅 +5 位作者 朱文彬 傅建军 罗明坤 邓玉婕 杨皓然 董在杰 《淡水渔业》 北大核心 2026年第1期86-95,共10页
为了选育肌肉多不饱和脂肪酸含量高的鳙(Hypophthalmichthys nobilis)新种质,本研究对同一养殖环境下的鳙[平均体重为(5.77±0.81)kg]肌肉组织进行脂肪酸检测,然后选取高水平和低水平多不饱和脂肪酸含量的鳙肌肉组织进行转录组测序... 为了选育肌肉多不饱和脂肪酸含量高的鳙(Hypophthalmichthys nobilis)新种质,本研究对同一养殖环境下的鳙[平均体重为(5.77±0.81)kg]肌肉组织进行脂肪酸检测,然后选取高水平和低水平多不饱和脂肪酸含量的鳙肌肉组织进行转录组测序。结果显示:共获得原始测序片段(raw reads)236749256个,过滤后得到的clean reads共236030318个。获得差异表达基因(Differentially expressed genes,DEGs)335个,其中上调基因264个,下调基因71个。获得单核苷酸多态性(Single nucleotide polymorphism,SNP)位点266279个。DEGs的KEGG富集通路主要为脂肪酸的生物合成、初级胆汁酸生物合成、甘油磷脂代谢和甘油脂质代谢等。脂肪酸生物合成通路中的关键差异基因为acacb和acsbg 1,且有42个SNP位点与关键基因acacb连锁,该连锁关系与脂肪酸合成显著相关。同时,与脂肪酸合成代谢相关的甘油磷脂代谢和甘油脂质代谢通路DEGs中均有lpin 1和lpin 2基因,可能与脂肪酸合成代谢相关,值得进一步关注。本研究通过转录组分析,筛选获得了与鳙肌肉多不饱和脂肪酸含量密切相关的脂肪酸的生物合成通路,以及该通路上2个差异表达基因acacb和acsbg 1。 展开更多
关键词 鳙(Hypophthalmichthys nobilis) 多不饱和脂肪酸 转录组 差异表达基因
在线阅读 下载PDF
Population distributions of alele frequency of apolipoprotein E by age and gender in Han Chinese 被引量:2
14
作者 张建刚 董秀珍 +2 位作者 杨伟军 陆晴 贺林 《中国药理学报》 CSCD 1999年第3期218-222,共5页
目的:研究在上海地区健康汉族人中不同年龄和性别的载脂蛋白E基因频率的群体分布.方法:本次调查包括649名健康汉族人(女:237人,男:412人).载脂蛋白E基因用PCR扩增,前引物:5′GGCACGGCTGTCCA... 目的:研究在上海地区健康汉族人中不同年龄和性别的载脂蛋白E基因频率的群体分布.方法:本次调查包括649名健康汉族人(女:237人,男:412人).载脂蛋白E基因用PCR扩增,前引物:5′GGCACGGCTGTCCAAGGAGCT3′;后引物:5′GATGGCGCTGAGGCCGCGCT3′.PCR产物用5单位限制性内切酶CfoⅠ酶切,用20%聚丙烯酰胺凝胶电泳分离.结果:ApoE3频率最高为864%,其次ApoE4频率为75%,ApoE2频率最低为62%.经χ2检验,等位基因及基因型频率分布符合HardyWeinberg平衡.结论:本项研究提供了正常中国汉族人群中载脂蛋白E三个等位基因2。 展开更多
关键词 载脂蛋白E 多态性 汉族 基因频率 RFLP
原文传递
Occurrence and patterns of nutritional traits and polycyclic aromatic hydrocarbons(PAHs)in sea cucumber(Holothuria poli)tissues:benefits and risk for human health 被引量:1
15
作者 Francesca Biandolino Isabella Parlapiano +5 位作者 Lucia Spada Antonella Di Leo Maria Calo Giovanni Fanelli Ermelinda Prato Santina Giandomenico 《Food Quality and Safety》 SCIE CSCD 2022年第2期287-309,共23页
Objectives:The paper evaluates the benefit and risk for human health associated with consumption of sea cucumber Holothuria poli(H.polil from Italian coasts(Central Mediterranean Sea).Materials and Methods:Body wall(B... Objectives:The paper evaluates the benefit and risk for human health associated with consumption of sea cucumber Holothuria poli(H.polil from Italian coasts(Central Mediterranean Sea).Materials and Methods:Body wall(BW),internal tunic(ITu),muscle bands(MBs),alimentary canal(AC),gonad(Gd),and respiratory tree(RT)of H.polii were analyzed for proximate composition.Moreover,amino acids(AAs),fatty acids(FAs)and polycyclic aromatic hydrocar bons(PAHs)were determined with high-performance liquid chromatography coupled with ultraviolet-visible spectroscopy(UPLC UV/Vis),gas chromatography-flame ionization detector(GC-FID)and gas chromatography mass spectrometry(GC-MS),respectively.Results:Differences in the contents of total amino acids(TAAs)occurred based on tissue and sex,with AC and MB of female and Gd of male showing higher contents(range 47.8-60.2 g/kg we weight(ww)).Glycine and glutamic acid were the most abundant.Polyunsaturated fatty acid(PUFA)was the major class of FAs and arachidonic acid and eicosapentenoic acid(EPA)were the predominant PUFA.n-3 PUFA showed higher content in Gd,AC,and RT,indicating higher quality.A favorable n-3/n-6 in the range of 1.04-1.67 was observed.PAHs showed values ranging from 23 to 207μg/kg ww with the highest levels in Gd and AC tissues and the lower in BW.Benzo[alpyrene,the most toxic compound,was detected in all tissues,of both sexes,at levels of 1.5-18μg/kg ww.Conclusion:All tissues of H.poli,although with differences among them,are valuable food and can contribute for a healthy diet.Excess cancer risk(CR)values for Gd and AC tissues were above the considerable CR threshold of one in 10000 established by the United States Environmental Protection Agency(USEPA)for high ingestion rate of this seafood. 展开更多
关键词 Holothuria poli nutitional quality polycyclic aromatic hydrocarbons risk assessment estimated weekly intake cancer risk
原文传递
iεepa kai Oσia:The Polis Life in the Parthenon Inventories of 5th Century BC
16
作者 张朵朵 《World History Studies》 2023年第1期46-56,共11页
"iεepa"and"Oσia"are two core concepts in research related to religion,which also play important roles in social life.The traditional view is that the dichotomy between"iεepa"and"O... "iεepa"and"Oσia"are two core concepts in research related to religion,which also play important roles in social life.The traditional view is that the dichotomy between"iεepa"and"Oσia"is an important method of research related to religion and that the border between"iεepa"and"Oσia"is clear.However,through reassessing the relationship between"iεepa"and"Oσia"on a case study of the Parthenon inventory,this article will demonstrate that the relationship between"iεepa"and"Oσia"is not one of complete opposition,but that it is in fact a unity of opposites.This relationship is primarily reflected in the three aspects of the Parthenon inventory:invocation,treasurers system and treasures type,aspects which also highlight the Athenian propensity to blend the sacred and secular spheres.These reassessed views shed new light on polis life,especially as regards public finance. 展开更多
关键词 iεepa kai Oσia Parthenon Inventories polis Life Public Finance
原文传递
The Effects of Macroeconomic Policies in a Mercantilist Economy
17
作者 Gaowang Wang Heng-fu Zou 《Frontiers of Economics in China-Selected Publications from Chinese Universities》 2018年第2期171-195,共25页
By introducing money and foreign exchange in the Zou (1997) model of mercantilism, the paper shows the effects of macroeconomic policies in mercantilist economies. It is shown that in the long run, consumption and f... By introducing money and foreign exchange in the Zou (1997) model of mercantilism, the paper shows the effects of macroeconomic policies in mercantilist economies. It is shown that in the long run, consumption and foreign asset accumu- lation increases as a result of stronger mercantilist sentiments, permanent increases in the consumption tax, increases in the monetary growth rate and purchases of foreign bonds. In the short run, however, macroeconomic disturbances including the mercan- tilist sentiments, the monetary growth rate, and the consumption tax have negative effects on current consumption and positive effects on current foreign asset accumula- tion, while purchasing foreign bonds has positive effects on both current consumption and current foreign asset accumulation. The theoretical explorations may provide a theoretical structure for hoarding international reserves and export-led growth stra- tegy utilized by emerging market economies. 展开更多
关键词 foreign asset accumulation MERCANTILISM MONEY macroeconomic poli-cies
原文传递
PLLA双向锯齿线联合A型肉毒毒素注射在面部年轻化中的应用
18
作者 秦志慧 卫露 +2 位作者 朱广明 张雷 尤军 《中国美容医学》 2026年第1期63-67,共5页
目的:研究左旋聚乳酸(PLLA)双向锯齿线联合A型肉毒毒素注射在面部年轻化中的应用效果。方法:研究对象为2021年2月-2023年2月在笔者医院行面部年轻化手术的就医者180例,以随机数字表法分为观察组(n=90,采用PLLA双向锯齿线联合A型肉毒毒... 目的:研究左旋聚乳酸(PLLA)双向锯齿线联合A型肉毒毒素注射在面部年轻化中的应用效果。方法:研究对象为2021年2月-2023年2月在笔者医院行面部年轻化手术的就医者180例,以随机数字表法分为观察组(n=90,采用PLLA双向锯齿线联合A型肉毒毒素注射治疗)及对照组(n=90,采用A型肉毒毒素注射治疗),比较两组就医者的面部年轻化效果、面部松弛状态、面部衰老程度、皮肤状态及不良反应发生率。结果:治疗3个月后,观察组就医者治疗总优良率高于对照组(P<0.05);两组就医者鼻低线-口裂线-瞳孔垂线弧度及瞳孔点至鼻唇沟与瞳孔垂线间距均较术前降低,且观察组低于对照组(P<0.05);两组就医者Hester中面部衰老分型中Ⅲ-Ⅳ型的占比均较术前降低,且观察组低于对照组(P<0.05);两组就医者皮肤水分、弹性评分均较术前升高,且观察组高于对照组(P<0.05),油脂及暗斑评分均较术前降低,且观察组低于对照组(P<0.05)。结论:将PLLA双向锯齿线联合A型肉毒毒素注射用于面部年轻化中疗效较好,其能改善就医者面部松弛状态及皮肤状态,减轻其面部衰老程度,安全性较高。 展开更多
关键词 左旋聚乳酸双向锯齿线 A型肉毒毒素 注射 面部年轻化 应用效果 皮肤状态
暂未订购
钠-A型分子筛对PVC热稳定性能影响研究 被引量:2
19
作者 杨笑春 刘会媛 +1 位作者 张青 于静 《中国塑料》 北大核心 2025年第2期77-81,共5页
通过刚果红实验发现钠-A型分子筛能够提高聚氯乙烯(PVC)的热稳定性能,其静态热稳定时间可达72 min,明显优于纯PVC(静态热稳定时间7 min)。将钠-A型分子筛分别与β-二酮、季戊四醇、亚磷酸一苯二异辛酯和环氧大豆油4种辅助热稳定剂进行... 通过刚果红实验发现钠-A型分子筛能够提高聚氯乙烯(PVC)的热稳定性能,其静态热稳定时间可达72 min,明显优于纯PVC(静态热稳定时间7 min)。将钠-A型分子筛分别与β-二酮、季戊四醇、亚磷酸一苯二异辛酯和环氧大豆油4种辅助热稳定剂进行复配得到复合热稳定剂,采用刚果红试纸法、热老化烘箱法和转矩流变仪法测定复合热稳定剂对PVC的静、动态热稳定性能,通过热失重法分析复合热稳定剂对PVC降解过程的影响。结果表明,当钠-A型分子筛与β-二酮质量比为1/1复配时热稳定效果最佳,静态热稳定时间可达84 min,动态热稳定时间可达1 137 s,塑化时间最短为104 s,平衡扭矩最小为37.94 N·m。 展开更多
关键词 聚氯乙烯 钠-A型分子筛 热稳定剂
在线阅读 下载PDF
ε-聚赖氨酸对苹果灰霉病菌的抑菌机制 被引量:2
20
作者 窦勇 董静 +3 位作者 陈成 胡佩红 刘芯池 孔令伟 《食品工业科技》 北大核心 2025年第3期196-203,共8页
为研究ε-聚赖氨酸(ε-PL)对苹果灰霉病菌Botrytis cinerea的抑制效果及其机制。用不同浓度的ε-PL处理B.cinerea,研究其对B.cinerea的菌落直径、孢子萌发、菌丝生长及对苹果灰霉病防治效果的影响,同时考察B.cinerea细胞通透性、抗氧化... 为研究ε-聚赖氨酸(ε-PL)对苹果灰霉病菌Botrytis cinerea的抑制效果及其机制。用不同浓度的ε-PL处理B.cinerea,研究其对B.cinerea的菌落直径、孢子萌发、菌丝生长及对苹果灰霉病防治效果的影响,同时考察B.cinerea细胞通透性、抗氧化酶活性、细胞可溶性蛋白与核酸的泄漏、丙二醛含量及活性氧的变化规律。结果表明:ε-PL对B.cinerea的最小抑菌浓度为400 mg/L,该浓度的ε-PL能有效控制苹果灰霉病;100 mg/L以上的ε-PL能显著抑制B.cinerea孢子萌发和菌丝生长(P<0.05),破坏孢子膜结构,增大孢子细胞的通透性,造成可溶性蛋白与核酸发生泄漏,使孢子形态呈现萎缩干瘪、甚至溶解现象;此外,100 mg/L以上的ε-PL能显著降低B.cinerea的超氧化物歧化酶、多酚氧化酶和过氧化氢酶的活性,升高丙二醛含量(P<0.05)。综上,ε-PL能通过破坏B.cinerea孢子细胞膜结构、增大细胞通透性、抑制抗氧化酶活性、促进活性氧的积累,进而增大孢子膜的脂质过氧化程度,损伤孢子结构,最终抑制苹果灰霉病菌的生长。此项研究可为ε-PL在苹果采后病害防治中的应用打下基础,具有较高的应用价值。 展开更多
关键词 Ε-聚赖氨酸 抑菌机制 苹果灰霉病 细胞泄漏 抗氧化酶
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部