促进染色质转录因子(facilitate chromatin transcription,FACT)在DNA复制、转录、损伤修复相关的染色质重塑过程发挥重要的作用。FACT复合物包含POB3/SSRP1(structure-specific recognition protein-1)和SPT16(suppressor of Ty 16)两...促进染色质转录因子(facilitate chromatin transcription,FACT)在DNA复制、转录、损伤修复相关的染色质重塑过程发挥重要的作用。FACT复合物包含POB3/SSRP1(structure-specific recognition protein-1)和SPT16(suppressor of Ty 16)两个亚基,该复合物及其亚基的功能虽在真菌、植物和动物上有些研究,但具体功能仍不完全清楚。该文以原生动物四膜虫为研究对象,对其促进染色质转录因子亚基Pob3进行研究。结果显示,嗜热四膜虫FACT复合物中的POB3基因在营养生殖时期和饥饿时期表达,在有性生殖时期表达上调。在生长期和饥饿期,Pob3定位于亲本大核和小核上;在有性生殖时期,Pob3定位于功能小核和新大核,在降解的小核和降解的亲本大核中定位消失。截短N-端的HA-Pob3Δ33在有性生殖前期定位在细胞质,但在有性生殖后期定位在配子和新发育的大核。截短C-端的HA-Pob3Δ87只定位在细胞质。POB3敲减突变株发生了异常的配子核和合子核的有丝分裂,导致有性生殖无法正常完成。结果表明,促进染色质转录因子亚基Pob3参与调控嗜热四膜虫细胞核的有丝分裂,对有性生殖的完成是必需的。展开更多
There are many access ends and information asymmetry in the management of offshore platform production facility personnel information. In the actual business, the problem is decomposed and a multi-layer logical archit...There are many access ends and information asymmetry in the management of offshore platform production facility personnel information. In the actual business, the problem is decomposed and a multi-layer logical architecture is selected to design and develop the POB plan management module applicable to offshore platform facilities. The main functions of this module include task management, facility management, area management, sea-going unit management, plan management, report management, authority control, and comprehensive query. It can efficiently solve on-site business problems and improve the efficiency of POB plan management for various professionals on land and at sea. In actual use, the module can well assist in completing POB plan management tasks and improve work efficiency.展开更多
文摘促进染色质转录因子(facilitate chromatin transcription,FACT)在DNA复制、转录、损伤修复相关的染色质重塑过程发挥重要的作用。FACT复合物包含POB3/SSRP1(structure-specific recognition protein-1)和SPT16(suppressor of Ty 16)两个亚基,该复合物及其亚基的功能虽在真菌、植物和动物上有些研究,但具体功能仍不完全清楚。该文以原生动物四膜虫为研究对象,对其促进染色质转录因子亚基Pob3进行研究。结果显示,嗜热四膜虫FACT复合物中的POB3基因在营养生殖时期和饥饿时期表达,在有性生殖时期表达上调。在生长期和饥饿期,Pob3定位于亲本大核和小核上;在有性生殖时期,Pob3定位于功能小核和新大核,在降解的小核和降解的亲本大核中定位消失。截短N-端的HA-Pob3Δ33在有性生殖前期定位在细胞质,但在有性生殖后期定位在配子和新发育的大核。截短C-端的HA-Pob3Δ87只定位在细胞质。POB3敲减突变株发生了异常的配子核和合子核的有丝分裂,导致有性生殖无法正常完成。结果表明,促进染色质转录因子亚基Pob3参与调控嗜热四膜虫细胞核的有丝分裂,对有性生殖的完成是必需的。
文摘There are many access ends and information asymmetry in the management of offshore platform production facility personnel information. In the actual business, the problem is decomposed and a multi-layer logical architecture is selected to design and develop the POB plan management module applicable to offshore platform facilities. The main functions of this module include task management, facility management, area management, sea-going unit management, plan management, report management, authority control, and comprehensive query. It can efficiently solve on-site business problems and improve the efficiency of POB plan management for various professionals on land and at sea. In actual use, the module can well assist in completing POB plan management tasks and improve work efficiency.
