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Calculating the Number of Pregnant Women Receiving Standardized Services for PMTCT of HIV in Liangshan Prefecture,Based on the Equivalent Method 被引量:1
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作者 QU Shui Ling WANG Ai Ling +3 位作者 PAN Xiao Ping WANG Xiao Yan LUO Hui Ming ZHANG Tong 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2020年第10期745-749,共5页
Objective To calculate the number of pregnant women who receive standardized prevention of mother-to-child transmission(PMTCT)services for HIV annually.Methods HIV-positive pregnant women in six counties of Liangshan ... Objective To calculate the number of pregnant women who receive standardized prevention of mother-to-child transmission(PMTCT)services for HIV annually.Methods HIV-positive pregnant women in six counties of Liangshan Prefecture in 2017 were selected as study subjects.The entire process,from when the subjects first received the PMTCT of HIV services to the end,was divided into four stages,which were further divided into 25 phases.The equivalent coefficient was used to indicate the weight of workload in each phase.Seven experts were invited to score the equivalent coefficient;the number of pregnant women who received standardized services to prevent the transmission of HIV was calculated.Results A total of 663 HIV-positive pregnant women were registered in six Liangshan Prefecture counties in 2017.This figure was converted into 7,780 person-months devoted to HIV-positive pregnant women,with 260 person-months(3.34%)spent on the first antenatal care,1,510 person-months(19.41%)during pregnancy,378 person-months(4.86%)on delivery,and 5,632 person-months(72.39%)on post-partum period.The equivalent coefficient calculation showed that 314 HIV-positive pregnant women received standardized PMTCT services.Conclusion The number of pregnant women receiving standardized services for the PMTCT of HIV can be calculated accurately using the equivalent method to identify the gap between the level of PMTCT of HIV intervention services needed and the actual workload. 展开更多
关键词 Equivalent method Standardized services pmtct Pregnant women HIV
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Evaluation of the Implementation of the WHO’s 2010 Guide on Prevention of Mother To-Child Transmission (PMTCT) of HIV/Aids: Case of Two Hospitals in Yaoundé 被引量:1
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作者 P. M. Tebeu E. Ngo Um Meka +3 位作者 E. Bechem C. Ndomo F. Essiben R. E. Mbu 《Open Journal of Obstetrics and Gynecology》 2017年第5期487-493,共7页
Introduction: The prevalence of HIV infection amongst pregnant women in Cameroon is 5.6%. Mother-to-child transmission is a major expansion factor. In 2010, Cameroon adopted new strategies pegged to WHO guidelines. Ob... Introduction: The prevalence of HIV infection amongst pregnant women in Cameroon is 5.6%. Mother-to-child transmission is a major expansion factor. In 2010, Cameroon adopted new strategies pegged to WHO guidelines. Objectives: The objective of this study was to evaluate the implementation of the new guidelines of prevention of mother to-child transmission (PMTCT) of HIV in the Yaoundé Central Hospital and the Yaoundé Teaching Hospital. Methodology: It was a cross sectional descriptive and prospective study over a period of 6 months in Yaoundé. It included all HIV-positive women, doing their antenatal care in the above cited hospitals, and having given their consent. The studied variables included socio demographic features, obstetrical history, the antenatal care, the initiation of anti retroviral (ARV) drugs, the ARV regimen, the number of years on ARV drugs, the mode of delivery and the mother and child outcome. The data was collected using a pre-tested questionnaire. They were obtained by interview of the seropositive pregnant women. Data were analysed using Epi info 3.5.3. Results: We performed 3104 antenatal consultations and 287 women were recruited in the study. The prevalence of HIV infection was 9.24%. The mean age of women was 28.77 (SD: 5.13) years. The women were aged between 20 and 29 years in 51.20%. Amongst the 156 women who knew their status before pregnancy, 109 (70.50%) had their first ANC in the first trimester. All were managed according to the 2010 WHO recommendations on PMTCT of HIV. Amongst the women unaware of their status, 25.20% had their booking ANC in the first trimester, 25.14% started ARVs at 14 weeks, 69.46% at 28 weeks. We had 125 live births, 84.8% by vaginal route, neonatal prophylaxis in all babies was effective. Conclusion: PMTCT of HIV is available and guidelines are well applied in Yaoundé. Late treatment initiation still remains a problem to optimize care. 展开更多
关键词 HIV ANC PREVENTION of MOTHER to CHILD TRANSMISSION (pmtct) ARV
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Missed Opportunities for Prevention of Mother-to-Child Transmission of HIV (PMTCT) in Ibadan, Southwest Nigeria 被引量:1
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作者 Babatunde O. Ogunbosi Regina E. Oladokun +10 位作者 Olutosin Awolude Biobele J. Brown Olubukola A. Adeshina Modupe Kuti Babafemi Taiwo Baiba Berzins Demetrious N. Kyriacou Ellen G. Chadwick Kikelomo Osinusi Isaac F. Adewole Robert L. Murphy 《World Journal of AIDS》 2014年第3期356-364,共9页
Background: Nigeria has the largest paediatric HIV-infected population in the world. Missed opportunities for prevention of mother-to-child transmission of HIV (PMTCT) compromise efforts at eliminating new pediatric H... Background: Nigeria has the largest paediatric HIV-infected population in the world. Missed opportunities for prevention of mother-to-child transmission of HIV (PMTCT) compromise efforts at eliminating new pediatric HIV infections. Methods: Six hundred children, aged < 15 years, presenting to the pediatric units of the University College Hospital (UCH), Ibadan Southwest Nigeria between June to December 2007 were studied. The demographics, HIV status and socioeconomic status of mothers and their children were studied. A 4-step hierarchy was used to assess the missed opportunities for PMTCT. Step 1: utilization of a health facility for antenatal care and delivery;Step 2: maternal HIV status determination during pregnancy;Step 3: provision of antiretroviral medication to HIV-infected mother and baby;and Step 4: avoidance of mixed feeding in HIV-exposed children. The rates of missed opportunities for PMTCT services at different steps in the PMTCT cascade, perinatal transmission rates, and associated factors were reported. Results: There were 599 mothers and 600 children (one set of twins), 60 (10%) were HIV infected and 56 (93.3%) of these were adjudged perinatally infected. Of 78 HIV-infected women, 7 (9.0%) accessed all interventions in the PMTCT cascade and 71 (91.0%) had missed opportunities for PMTCT. Missed opportunities for PMTCT occurred 42.9% in cascade Step 1, 64.2% in Step 2, 52.6% in step 3 and 73.7% in Step 4. All mother-baby pairs who accessed complete PMTCT interventions received care at a teaching hospital. Among infants with perinatal HIV infection, 53 (94.6%) were born to mothers who had missed opportunities for PMTCT. Most women with missed opportunities attended antenatal care outside the teaching hospital setting and belonged to low socioeconomic status. Conclusion: It is imperative to expand PMTCT access to women who receive antenatal care outside the teaching hospitals and to those of low socioeconomic status. 展开更多
关键词 HIV PERINATAL Prevention pmtct MISSED OPPORTUNITIES
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The Intersectionality Framework and Its Contribution to Nursing Knowledge Related to the Prevention of Mother to Child Transmission (PMTCT) Program 被引量:1
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作者 Joyce Kamanzi Solina M. Richter +1 位作者 Pauline Paul Kimberly Jarvis 《Open Journal of Nursing》 2021年第12期1052-1063,共12页
Nurses work within a multidimensional scope of practice, which includes a reactive approach of treating health problems, a proactive stance of health promotion, and disease prevention. The purpose of this paper is to ... Nurses work within a multidimensional scope of practice, which includes a reactive approach of treating health problems, a proactive stance of health promotion, and disease prevention. The purpose of this paper is to discuss the contribution of the intersectionality framework in building nursing knowledge related to the PMTCT of HIV and show how the intersectionality framework can contribute to the improvement of nursing practice, policy, and research related to PMTCT of HIV. A comprehensive literature review was conducted to be able to discuss the contribution of intersectionality framework in nursing knowledge. Intersectionality is a nice perspective that gives insight into different identities that link and work together to provide inequalities. Intersectionality is a well-suited approach in a nursing profession where we strive to offer efficient and better care to our patients or clients;an excellent tool to explore more on the roots of inequality, oppression, and discrimination. 展开更多
关键词 Intersectionality Nursing Knowledge pmtct HIV
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基于PMTCT模式的梅毒母婴传播控制效果 被引量:1
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作者 刘兰萍 刘菊花 刘清远 《临床医学研究与实践》 2020年第13期182-183,共2页
目的探讨基于预防传染性疾病母婴传播(PMTCT)模式的梅毒母婴传播控制效果。方法选取10600例于我院进行产检的孕妇作为研究对象,根据产检时间将2018年1月至9月的5300例孕妇设为研究组(基于PMTCT模式管理),将2016年1月至9月的5300例孕妇... 目的探讨基于预防传染性疾病母婴传播(PMTCT)模式的梅毒母婴传播控制效果。方法选取10600例于我院进行产检的孕妇作为研究对象,根据产检时间将2018年1月至9月的5300例孕妇设为研究组(基于PMTCT模式管理),将2016年1月至9月的5300例孕妇设为参照组(常规模式)。比较两组的管理效果。结果研究组与参照组的妊娠合并梅毒孕妇分别为17、16例。研究组规范治疗率高于参照组,不良妊娠结局总发生率低于参照组(P<0.05)。结论基于PMTCT模式管理对梅毒母婴传播控制效果显著。 展开更多
关键词 梅毒 母婴传播 pmtct模式
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Postnatal PMTCT: Women’s Perception Barriers at a Johannesburg Health Centre, South Africa
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作者 Benon Ngyende Blaise Bucyubaruta Charles Mugero 《Health》 2020年第11期1511-1525,共15页
Background: Maximising women’s participation and ensuring optimal outcomes will require that the women’s perception barriers to postnatal prevention of Mother-to-Child Transmission (PMTCT) programme of HIV be addres... Background: Maximising women’s participation and ensuring optimal outcomes will require that the women’s perception barriers to postnatal prevention of Mother-to-Child Transmission (PMTCT) programme of HIV be addressed. However, little is known about women’s perception barriers to postnatal PMTCT programme of HIV and how these barriers affect the women’s health seeking behavior and uptake. Objective: This study sought to explore the women’s perception barriers to postnatal PMTCT programme at a Johannesburg Community Health Centre during April-May, 2016. Methods: A qualitative study on 30 women (aged 20 - 39 years) was conducted at a Johannesburg community health (CHC), South Africa, during May-June 2016, after obtaining their consent. The data was analysed thematically to understand women’s perception barriers to postnatal PMTCT programme. Results: The study found that inadequate counselling was perceived to be the single key health service barrier to PMTCT programme. At the individual level, adherence to ART was considered the leading women’s barriers to the postnatal PMTCT. Exclusive breastfeeding was, however, perceived as important women’s barriers to the postnatal PMTCT. Inadequate emotional support from families and community was a noteworthy women’s perception barrier to the programme. Conclusion: The study makes two recommendations: firstly, the staff, programme managers and health policy makers need to be aware of the women’s perception barriers to the postnatal PMTCT programme. Secondly, the programme should be strengthened by addressing perception barriers to the programme to enhance women participation to ensure optimal outcomes for women and their infants. 展开更多
关键词 Postnatal pmtct Barriers Women Perception HIV South Africa
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Missed Prevention of Mother-to-Child Transmission of HIV (PMTCT) Visits and Associated Programmatic Predictors: A Pilot Study
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作者 Augustine Ndaimani Inam Chitsike +1 位作者 Clara Haruzivishe Babill Stray-Pedersen 《Advances in Infectious Diseases》 2017年第4期107-117,共11页
Missed Prevention of Mother-to-Child Transmission of HIV (PMTCT) visits have contributed to the delayed achievement of elimination of mother-to-child transmission of HIV. Missed visits promote attrition from preventio... Missed Prevention of Mother-to-Child Transmission of HIV (PMTCT) visits have contributed to the delayed achievement of elimination of mother-to-child transmission of HIV. Missed visits promote attrition from prevention of mother-to-child transmission of HIV program and antiretroviral drug resistance. The purpose of the study was to determine the prevalence of missed PMTCT visits and its associated predictors. A descriptive cross sectional survey was carried out at a District Hospital in Goromonzi, Zimbabwe. Fifty-three women completed closed-ended questionnaires pertaining to PMTCT visits and exposure to PMTCT activities. A total of 24.5% missed at least one scheduled PMTCT visit. Statistically significant predictors of not missing a PMTCT visit were satisfaction with family support (β = &minus;0.73, p = 0.029) and level of satisfaction with PMTCT services (β = &minus;0.00076;p = 0.04). The number of days by which scheduled visits were missed were inversely correlated with visit number (β = &minus;2.99, p = 0.04). Enhanced family support and quality improvement to improve patient satisfaction may reduce missed visits. Availing women with a more active role in PMTCT may also reduce the prevalence of missed visits. 展开更多
关键词 MISSED VISITS OPTION B Plus Pilot Study pmtct (Prevention of Mother-to-Child Transmission of HIV) PREDICTORS
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Factors of Failure of Community Interventions of PMTCT Activities in Haut Katanga in the Democratic Republic of Congo
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作者 Mpoyi Tabitha Ilunga Mukengeshayi Abel Ntambue +1 位作者 Sakatolo Zambeze Jean Baptiste Kakoma Kaj Françoise Malonga 《Health》 2023年第6期667-675,共9页
The objective of the study was to identify the failure factors of community interventions in terms of HIV activities in the province of Haut-Katanga during the year 2016. Materials and Methods: The study was phenomeno... The objective of the study was to identify the failure factors of community interventions in terms of HIV activities in the province of Haut-Katanga during the year 2016. Materials and Methods: The study was phenomenological of the factors, carried out in Haut Katanga. All health facilities (FOSAs) having integrated the prevention of transmission of HIV infection from mother to child (PMTCT) were included in the study. The collection was carried out through individual semi-structured interviews with PMTCT focal points, mentor mothers and people living with HIV (PLWHA) cared for in some of these health facilities (FOSAs). The number of participants was determined by the saturation of responses. Nvivo v.11 software was used for the analyses. The data of each woman was handled confidentially. The authorization of the ethics committee of the University of Kinshasa ESP/CE091/2015, the free and written consent, was obtained before collecting the information. Results: It was observed the socio-cultural factors of success and failure of the interventions: the social fear generated by contradictory messages in the sensitization of the community;the lack of an obvious strategy for the involvement of the partner;the weak coordination of community care activities between the central office of the health zone;the FOSA and the community worker: low interest in community care evidenced by weak accountability of FOSAs, community and program providers in this regard;that relates to community activities;coordination of care between care units;overload of the staff in charge of activities within the health structure and their low motivation;the low communication time devoted to people living with HIV in the FOSAs. Conclusion: The study shows that interventions that can improve the quality and outcomes of prevention of mother-to-child transmission of HIV (PMTCT) services can be directly linked to the program itself, as well as come from another or the community, which generally remains the weak link in which efforts are even less noticeable, at least as far as PMTCT is concerned. Integrating care data for the mother-child couple improve the continuum of services between the different care units as well as the quality of data management. 展开更多
关键词 Success and Failure Factors Community Interventions pmtct
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Use of Critical Ethnography to Study the PMTCT Program
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作者 Joyce Kamanzi Solina M. Richter +1 位作者 Pauline Paul Kimberly Jarvis 《Advances in Infectious Diseases》 2022年第1期147-158,共12页
Background: Despite the efforts at establishing Prevention of Mother to Child Transmission (PMTCT) programs in Rwanda, there are still children who are becoming infected through mother-to-child transmission of HIV. Th... Background: Despite the efforts at establishing Prevention of Mother to Child Transmission (PMTCT) programs in Rwanda, there are still children who are becoming infected through mother-to-child transmission of HIV. The purpose of our research study was to explore the experiences of HIV positive women using PMTCT program to prevent HIV transmission in Rwanda. Methodology: In this study, a qualitative approach using a critical ethnographic design was used to answer to our research question and with the aim to discover the meaning, process, and context of the studied phenomenon. In this paper, we discussed ethnography, critical ethnography, and its related philosophical assumptions as well as illustrating the rational for the use of critical ethnography to study the PMTCT program. Critical ethnography ultimately will contribute to raising awareness on how we can prevent new infections among children born from HIV positive mothers who are using the PMTCT program. The findings suggested a wide range of challenging factors that are shaped by social, political, cultural, economic, ethnic, and gender values, and that directly and indirectly affect the uptake of the PMTCT program. While using the critical realist ontology, we discovered multiple truths about the challenging factors for HIV+ mothers experience to uptake the PMTCT program. We triangulated their experiences with the findings gathered from healthcare providers, PMTCT leaders and policymakers, field observation, and document analysis. No previous studies on this phenomenon used a critical lens to explore the reality behind a wide range of experiences of mothers using the PMTCT program to prevent HIV transmission in Rwanda. Conclusion: The critical nature of this inquiry contributed to the depth and breadth of knowledge related to the delivery of the PMTCT program to prevent MTCT of HIV. 展开更多
关键词 Critical Ethnography HIV Nursing Knowledge pmtct
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HIV Status Disclosure Rate to a Sexual Partner, Associated Factors and Outcomes among Pregnant Women in PMTCT Care in Two Large HIV Facilities in Abuja, Nigeria
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作者 Prosper Okonkwo Oluseye Ajayi +1 位作者 Ojukwu Chinonso Nnenna Abiodun Isah 《World Journal of AIDS》 2023年第4期193-209,共17页
HIV status disclosure to partners is critical in improving the health and well-being of mother-infant dyad in the prevention of HIV transmission from mother to child (PMTCT) program. This study assesses the HIV disclo... HIV status disclosure to partners is critical in improving the health and well-being of mother-infant dyad in the prevention of HIV transmission from mother to child (PMTCT) program. This study assesses the HIV disclosure rate to intimate partners, associated factors, and outcomes among women in the PMTCT program in two large HIV clinics in Abuja, Nigeria. A descriptive cross-sectional study employed a multi-stage sampling technique in selecting 220 pregnant women enrolled in PMTCT care in two clinics. Outcomes measures include HIV status disclosure to intimate partner, women’s viral suppression status (suppressed < 1000 copies/mL, unsuppressed ≥ 1000 copies/mL), and previous MTCT experience. Exposure variables include the participant’s socio-demographic characteristics and HIV care history. Data were presented using frequency tables. Simple and multivariate logistic regression was done to ascertain the predictors of HIV status disclosure and assess the association between HIV disclosure, viral suppression, and MTCT experience at a p-value of less than 0.05. Only 205 (96.7%) entries were completed and analyzed A larger percentage of the participants were married women, 158 (77.1%), within the age group 26 - 35 years (53.3%). Women’s HIV status disclosure rate to intimate partners was 49.3% (101/205). Factors associated with HIV disclosure rate to intimate partners at the univariate level were the participant’s age, Christian religion [COR: 1.80, 95%CI: 1.04 - 3.21, p = 0.04], full employment [COR: 1.92, 95%CI: 1.10 - 3.34, p = 0.02], HIV positivity prior to PMTCT enrollment [COR: 2.88, 95%CI: 1.26 - 6.59, p < 0.01], duration on antiretroviral therapy [COR: 1.07, 95%CI: 1.01 - 1.13, p = 0.03], and knowledge of partner’s HIV status [COR: 0.20, 95%CI: 0.08 - 0.51, p < 0.01]. Only HIV positivity prior to PMTCT enrollment [AOR: 3.27, 95%CI: 1.23 - 8.70, p < 0.01] and awareness of the partner’s HIV status, [AOR: 0.17, 95%CI: 0.06 - 0.49, p < 0.01] were significant predictors of HIV status disclosure after controlling for confounder. The two study outcomes;women’s viral suppression and MTCT experience were not significantly associated with participants’ HIV status disclosure to intimate partners. Our study shows that HIV disclosure to intimate partners is still a big challenge among pregnant women in PMTCT settings in Nigeria, with awareness of the partner’s HIV status and the type of patient enrollment in the PMTCT setting being the two strong predictors of pregnant women’s HIV disclosure status to partners. 展开更多
关键词 HIV Status Disclosure Intimate Partner pmtct Pregnant Women
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HIV Prevalence amongst Pregnant Women Clients Attending Antenatal Clinic at the Faith Alive Foundation and PMTCT Centre, Jos Plateau State
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作者 Anyaka Charles Oyebode Tinuade +3 位作者 Musa Jonah Isichei Mercy Anyaka Ifechi Isichei Christian 《World Journal of AIDS》 2016年第2期59-64,共6页
Introduction: HIV infection and AIDS is a public health problem worldwide, particularly affecting the populace in resource challenged setting like sub-saharan Africa. Women of reproductive age are mostly affected and ... Introduction: HIV infection and AIDS is a public health problem worldwide, particularly affecting the populace in resource challenged setting like sub-saharan Africa. Women of reproductive age are mostly affected and infected with the HIV disease. Methodology: A cross-sectional study of 216 randomly selected women that booked for antenatal care at the Faith Alive Foundation and PMTCT centre Jos between 1st July to 31st December, 2014 was carried out. Information regarding age, parity, gestational age at booking, educational status and HIV sero-status of the clients was analysed. Screening test was conducted in a serial two step approval using determine and UNIGOLD as the confirmatory test, while STAT-PAK was the tie-beaker with discordant result as per the national algorithm. Positive samples were confirmed by western blot method. Result: A total of 18 women out of the 216 women studied were positive giving a sero-prevalence rate of 8.3%. The highest sero-prevalent rate was amongst 25 - 29 years age group (31.5%). Women of parity 1 - 4 constituted the highest group of 62.9%. Majority of the women 65.7% booked in the second trimester while 26.9% booked in the 3rd trimester. Most of the women 47.2% had secondary school education while only 5.6% of them had no form of education. Conclusion: HIV infection prevalence rate among antenatal attendants at Faith Alive Foundation and PMTCT centre Jos is still high. Multisectorial approach and intervention strategies should be further scaled up for the prevention of vertical transmission of the virus. However, it is worth noting that it is mainly an HIV/AIDS hospital which should have affected the outcome. 展开更多
关键词 HIV Prevalence Antenatal Clinic Faith Alive Foundation and pmtct Centre Jos Plateau State
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艾滋病病毒母婴传播阻断效果分析 被引量:25
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作者 孙定勇 韩伯勇 +4 位作者 许淑琴 王奇 崔兆麟 郭万申 王哲 《中国公共卫生》 CAS CSCD 北大核心 2006年第5期533-534,共2页
目的分析艾滋病患病率较高的河南省某县婚龄妇女及孕妇、产妇的人类免疫缺陷病毒(HIV)感染状况;探讨实行多种干预措施后的效果及科学、简单、经济的阻断HIV经母婴传播的评价方法。方法采取整群抽样方法,对该县婚龄妇女及孕产妇进行连续4... 目的分析艾滋病患病率较高的河南省某县婚龄妇女及孕妇、产妇的人类免疫缺陷病毒(HIV)感染状况;探讨实行多种干预措施后的效果及科学、简单、经济的阻断HIV经母婴传播的评价方法。方法采取整群抽样方法,对该县婚龄妇女及孕产妇进行连续4年HIV的监测,采取实验流行病学研究方法对不同目标人群采取不同干预措施(提供咨询、暂缓结婚、自愿终止妊娠、母婴抗病毒药物服用);并对HIV阳性人群进行描述性研究。对HIV感染产妇所分娩的婴儿分别进行0、9和18个月时随访与检测;初步对产妇和婴儿的药物阻断效果进行评价。结果4年来,共对婚龄妇女13 693人、孕妇32155人、产妇11367人进行HIV抗体检测;其中确认HIV阳性的婚龄妇女39人、孕妇112人、产妇81人;81名产妇所分娩的婴儿85人中,19名满18月龄婴儿HIV抗体检测阴性,其余仍在随访中。结论采用多种阻断艾滋病经母婴途径传播的干预模式,取得一定效果。 展开更多
关键词 艾滋病 干预措施 母婴阻断(pmtct) 孕产妇 奈韦拉平
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HIV双阳家庭孕妇早期程序化ART干预和产后婴儿母婴阻断技术的研究进展
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作者 周京雨 陈文茜 +3 位作者 郑涵文 梁童昕 张玲 刘慧 《预防医学论坛》 2025年第9期715-720,共6页
HIV双阳家庭是指夫妻双方均为HIV感染者。对于这类家庭中的孕妇来说,抗逆转录病毒治疗(antiretroviral therapy,ART)和母婴阻断技术是预防母婴传播(prevention of mother-to-child transmission,PMTCT)的关键。早期ART干预可有效降低母... HIV双阳家庭是指夫妻双方均为HIV感染者。对于这类家庭中的孕妇来说,抗逆转录病毒治疗(antiretroviral therapy,ART)和母婴阻断技术是预防母婴传播(prevention of mother-to-child transmission,PMTCT)的关键。早期ART干预可有效降低母婴传播的风险,但依从性管理、伴侣间交叉感染及社会心理压力仍是挑战。本文综述了程序化ART的实施标准、临床效果及母婴阻断技术的进展,并探讨了其联合应用的协同效应及经济价值。尽管干预措施的落地使得母婴传播率有了明显的下降,但资源不均、耐药性监测不足等因素仍然限制了干预效果。未来,HIV母婴传播的防控应采取更加综合的策略,包括优化个性化ART方案、强化家庭健康教育、减少社会歧视,并结合长效抗病毒药物与新兴技术等,以期进一步降低HIV母婴传播的风险。 展开更多
关键词 艾滋病 双阳家庭 抗逆转录病毒治疗 母婴阻断 干预措施
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高流行地区HIV感染产妇配偶HIV检测情况及影响因素分析 被引量:7
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作者 王潇滟 王爱玲 +5 位作者 王芳 乔亚萍 王前 窦丽霞 苏敏 张彤 《中国艾滋病性病》 CAS 北大核心 2015年第6期493-496,522,共5页
目的了解中国四川、云南、新疆三个艾滋病高流行地区,艾滋病病毒(HIV)感染产妇配偶的检测情况及影响因素,分析近年来配偶的HIV检测结果及感染的危险途径。方法选取3个艾滋病疫情相对高发省(自治区)中的3个地区(市、州)作为调查地区,常... 目的了解中国四川、云南、新疆三个艾滋病高流行地区,艾滋病病毒(HIV)感染产妇配偶的检测情况及影响因素,分析近年来配偶的HIV检测结果及感染的危险途径。方法选取3个艾滋病疫情相对高发省(自治区)中的3个地区(市、州)作为调查地区,常规收集2012-2014年间,HIV感染产妇在医疗保健机构接受预防艾滋病母婴传播服务时所提供的配偶的HIV检测相关信息,并通过国家预防艾滋病、梅毒和乙型肝炎母婴传播管理信息系统报告与收集相关数据,分析配偶HIV检测现状及感染途径等相关信息。结果共调查2007例HIV感染产妇及其配偶。其中接受过HIV检测的配偶占69.7%(1399人),检测结果为阳性者占63.6%(890/1399)。2012-2014年,各年配偶检测阳性率分别为60.7%(250/412)、64.2%(327/509)和65.5%(313/478),差异有统计学意义(χ2=11.71,P<0.05)。37.8%(758/2007)的人报告有过注射吸毒行为。产妇及配偶均为HIV阳性的家庭,在孕期接受预防艾滋病母婴传播服务的比例为62.1%,高于其他类型家庭的49.6%,差异有统计学意义(χ^(2)=46.22,P<0.01)。结论配偶的HIV检测阳性率逐年提高,产妇及其配偶均为HIV感染的家庭,在孕期接受预防艾滋病母婴传播服务的比例较高,产妇及配偶的年龄、文化程度、婚姻状况、妊娠经历等,均为配偶接受HIV检测的影响因素。应针对不同类型的人群加强HIV检测的力度。 展开更多
关键词 艾滋病病毒 产妇 配偶 母婴传播 影响因素
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感染HIV的孕产妇预防艾滋病母婴传播服务需求与障碍分析 被引量:39
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作者 王临虹 方利文 +2 位作者 龚双燕 乔亚萍 苏穗青 《中国艾滋病性病》 CAS 2006年第1期10-12,15,共4页
目的了解艾滋病病毒(HIV)感染孕产妇的预防艾滋病母婴传播服务需求与服务利用障碍。方法对某艾滋病高发地区,自2003年以来截至2004年10月发现并分娩的HIV感染孕产妇进行问卷调查。结果13.79%的孕产妇不愿意接受产前检查,5.17%的孕产妇... 目的了解艾滋病病毒(HIV)感染孕产妇的预防艾滋病母婴传播服务需求与服务利用障碍。方法对某艾滋病高发地区,自2003年以来截至2004年10月发现并分娩的HIV感染孕产妇进行问卷调查。结果13.79%的孕产妇不愿意接受产前检查,5.17%的孕产妇不愿意住院分娩,怕歧视、担心检查和住院分娩费用高等是孕产妇不接受孕产期保健的主要原因;96.43%的孕产妇愿意本人和给孩子服用抗逆转录病毒药物预防艾滋病母婴传播,但只有87.50%的孕产妇服用了抗HIV药物,未服药的原因为临产急诊分娩,未得到检测结果,延误了孕产妇和婴儿的服药时机;89.29%的孕产妇希望其所生婴幼儿获得随访服务,但只有58.93%的婴幼儿得到过随访服务,其中51.52%的婴幼儿在出生后3个月内得到首次随访;怕别人知道自己的感染情况是不愿意接受随访的主要原因;近7%的孕产妇不愿意或不知道要给所生的婴幼儿进行HIV抗体检测。结论育龄妇女和孕产妇艾滋病检测不及时、非住院分娩、婴幼儿随访服务薄弱、经济负担、社会歧视等问题,是预防艾滋病母婴传播服务利用的主要障碍,预防艾滋病母婴传播综合能力亟待加强。 展开更多
关键词 艾滋病病毒感染孕产妇 预防艾滋病母婴传播 服务需求 障碍
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76例经艾滋病母婴阻断治疗的HIV阳性孕妇产后的临床体征和免疫功能变化 被引量:10
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作者 刘帅凤 邓小娥 +2 位作者 于丽 唐志荣 刘伟 《中国艾滋病性病》 CAS 北大核心 2015年第5期385-387,391,共4页
目的分析经艾滋病母婴阻断治疗(PMTCT)艾滋病病毒(HIV)阳性孕产妇,产后的临床体征、血色素、肝功能及免疫功能变化情况,为进一步指导艾滋病母婴阻断工作提供科学治疗依据。方法对广西2004-2010年76例经PMTCT的HIV阳性孕产妇,在产后2年... 目的分析经艾滋病母婴阻断治疗(PMTCT)艾滋病病毒(HIV)阳性孕产妇,产后的临床体征、血色素、肝功能及免疫功能变化情况,为进一步指导艾滋病母婴阻断工作提供科学治疗依据。方法对广西2004-2010年76例经PMTCT的HIV阳性孕产妇,在产后2年定期随访,其中31例产后继续接受高效抗反转录病毒治疗(HAART),45例产后停止HAART,对比分析她们的临床体征及实验室检测的血色素(HGB)、中性粒细胞(NC)、肝功能(ALT)和免疫功能[CD+4T淋巴细胞(简称CD4细胞)]的变化。结果在31例产后服药的孕产妇中,4例在产后平均2年后出现司坦夫定(D4T)药物关联的体型改变,2例自产后1年内出现严重的齐多夫定(AZT)贫血;45例产后停药者未出现相关临床体征。31例产后服药的孕产妇,在产后2年内CD4细胞计数比PMTCT前有显著性提高。45例产后停药的孕产妇,其CD4细胞计数在产后1年以后有显著性下降。31例产后服药和45例产后停止服药的孕产妇,产后2年定期随访HGB,NC,ALT均无显著性变化。结论广西孕产妇在服用AZT药后,对部分孕产妇血色素影响明显,部分孕产妇服用D4T治疗2年后有脂肪转移严重不良反应。艾滋病母婴阻断后停药的孕产妇CD4细胞水平下降较快。在艾滋病母婴阻断后停药或继续服药的孕产妇,其产后2年内的HGB、NC、ALT影响不明显。 展开更多
关键词 艾滋病病毒孕产妇 艾滋病母婴阻断 高效抗反转录病毒治疗 CD+4T淋巴细胞 血色素 丙氨酸转氨酶 中性粒细胞
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孕妇HIV抗体检测服务利用现状及影响因素 被引量:10
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作者 方利文 王临虹 王前 《中国公共卫生》 CAS CSCD 北大核心 2008年第4期393-394,共2页
目的了解我国部分艾滋病高发地区孕妇对人类免疫缺陷病毒fHIv)抗体检测服务的利用情况及其影响因素。方法2005年6~7月在新疆维吾尔自治区和云南省2个艾滋病高发地区。对接受孕期保健的774名孕妇进行HIV抗体检测服务状况调查。结果2个... 目的了解我国部分艾滋病高发地区孕妇对人类免疫缺陷病毒fHIv)抗体检测服务的利用情况及其影响因素。方法2005年6~7月在新疆维吾尔自治区和云南省2个艾滋病高发地区。对接受孕期保健的774名孕妇进行HIV抗体检测服务状况调查。结果2个地区孕妇HIV抗体检测率为29.33%,新疆维吾尔自治区和云南省现场孕妇HIV抗体检测率分别为34.27%,21.94%。接受过检测前咨询、配偶受教育程度较高的孕妇HIV抗体检测率高。结论我国部分艾滋病高发地区孕妇对HIV抗体检测服务利用不足,应加强检测前咨询服务提供,争取配偶参与,提高孕妇对HIV抗体检测服务的利用。 展开更多
关键词 艾滋病 母婴传播 人类免疫缺陷病毒(HIV)抗体检测 自愿咨询与检测 影响因素
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广州市2002-2013年HIV母婴传播阻断干预情况分析 被引量:7
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作者 赵宇腾 秦发举 +2 位作者 韩志刚 高凯 徐慧芳 《中国艾滋病性病》 CAS 北大核心 2015年第11期939-941,共3页
目的了解广州市2002-2013年报告的艾滋病病毒(HIV)抗体阳性孕产妇的疫情,以及母婴传播干预情况。方法运用趋势卡方分析,对2002-2013年报告的HIV抗体阳性孕产妇病例的晚发现、接受母婴阻断干预与随访等情况进行分析。结果 2002-2013年,... 目的了解广州市2002-2013年报告的艾滋病病毒(HIV)抗体阳性孕产妇的疫情,以及母婴传播干预情况。方法运用趋势卡方分析,对2002-2013年报告的HIV抗体阳性孕产妇病例的晚发现、接受母婴阻断干预与随访等情况进行分析。结果 2002-2013年,广州市累计报告HIV抗体阳性孕产妇278例,现存活261例。其中常住病例占64.4%(168例),平均年龄为27.6岁,异性传播占85.4%(223例),HIV感染者占70.1%(183例),AIDS病例所占比例呈下降的趋势(趋势χ2=8.46,P=0.004);接受HIV母婴阻断干预措施的病例占66.5%;常住病例中选择继续妊娠者所占比例(51.8%)高于非常住病例(38.7%)(χ2=4.556,P=0.033);已分娩婴儿中失访比例为41.4%。结论应加强孕产妇人群及其配偶的HIV抗体检测工作,孕产妇病例分娩婴儿的随访监测工作,是母婴传播干预工作的重点。 展开更多
关键词 艾滋病病毒阳性孕产妇 母婴传播 干预
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艾滋病不同流行区防治母婴传播的策略研究:基于卫生经济学评价的证据 被引量:6
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作者 贾琳 岳一姬 +1 位作者 赵旭晖 贾文霄 《新疆医科大学学报》 CAS 2016年第9期1192-1196,共5页
目的通过综合分析已发表的文献,探讨低收入和中等收入国家预防艾滋病母婴传播的成本-效果、成本-效用与成本-效益。方法回顾1994年-2015年期间已发表的有关低收入和中等收入国家预防艾滋病母婴传播经济学评价的文献,分析各国的成本-效... 目的通过综合分析已发表的文献,探讨低收入和中等收入国家预防艾滋病母婴传播的成本-效果、成本-效用与成本-效益。方法回顾1994年-2015年期间已发表的有关低收入和中等收入国家预防艾滋病母婴传播经济学评价的文献,分析各国的成本-效果、成本-效用和成本-效益,对其数据进行提取、整合。结果 13篇文献关注的是成本-效果,3篇文献研究的是成本-效用,9篇文献既研究了成本-效果又研究了成本-效用。结论在低、中等收入国家,预防艾滋病病毒母婴传播成本-效果最好的干预措施是孕妇自愿咨询检测(VCT)和短期口服抗逆转录病毒治疗方案(HIVNET012)/齐多夫定与抗逆转录病毒药物合用的治疗方案(ACTG076)的同时使用。成本-效用最好的干预措施是孕期抗逆转录病毒(ACTG076)和28w+HIVNET012+HIV阳性儿童的抗逆转录病毒治疗。成本-效果和成本-效用能够同时实现的干预措施是药物的使用,且最好在产后1w使用。 展开更多
关键词 艾滋病 母婴传播 经济学评价 系统评价 策略
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