Objective: To evaluate the effects of surgical trauma of open surgery on the patients with gastric carcinoma who underwent different lymph node dissection. Methods:Total 30 patients with gastric carcinoma were divided...Objective: To evaluate the effects of surgical trauma of open surgery on the patients with gastric carcinoma who underwent different lymph node dissection. Methods:Total 30 patients with gastric carcinoma were divided into three groups (D1, D2, and D3) according to the extent of lymph node dissection. Peripheral blood samples were taken to measure the levels of interleukin-6 (IL-6), interleukin-8 (IL-8), C-reactive protein (CRP) and polymorphonuclear elastase (PMNE). Ad- ditionally, leucocytes and lymphocytes counts in peripheral serum were also detected. Results: All the three groups showed a significant increase of the levels of IL-6, IL-8, CRP and PMNE after operation. There was no significant difference between D1 and D2 groups. When the comparison was made between D3 group and the other two groups, it showed higher concentration of IL-6, IL-8, CRP and PMNE in serum of D3 group. Leucocytes count showed no difference among the three groups. After operation, the patients in three groups had transient lymphocytes decrease on the second and third postoperative days, the lymphocytes count in D3 group was still lower while those in D1 and D2 groups began to increase. Conclusion: IL-6, IL-8, CRP and PMNE can be used to monitor surgical stress. Using these parameters, we found that extended lymph node dissec- tion of D3 group led to more postoperative stress than D1 and D2 groups.展开更多
With the rise of digital transactions, e-Wallets have become prime targets for fraudulent activity. Early detection of suspicious transactions is therefore crucial to protect users and maintain trust in these systems....With the rise of digital transactions, e-Wallets have become prime targets for fraudulent activity. Early detection of suspicious transactions is therefore crucial to protect users and maintain trust in these systems. This article proposes a mathematical model based on a Mixed Integer Program (MIP) to identify and block suspicious transactions. This mathematical approach is designed to analyze e-Wallet transactions in real time by combining integer and continuous decision variables, offering greater flexibility in modeling fraud detection constraints. It considers parameters such as transaction cost, geographical location, type of device used for the transaction, IP address and other potential fraud indicators. Assigning suspicion scores to each transaction enables the model to identify risks that become habitual behavior and mark them as suspicious. Tests carried out on 10,000 digital transactions show that using PMNE significantly improves the detection of fraudulent transactions by identifying the most critical anomalies in terms of accuracy, adaptability and operational efficiency. The model also offers greater accuracy, reducing the number of false positives and false negatives, enabling faster intervention to block truly suspicious transactions.展开更多
文摘Objective: To evaluate the effects of surgical trauma of open surgery on the patients with gastric carcinoma who underwent different lymph node dissection. Methods:Total 30 patients with gastric carcinoma were divided into three groups (D1, D2, and D3) according to the extent of lymph node dissection. Peripheral blood samples were taken to measure the levels of interleukin-6 (IL-6), interleukin-8 (IL-8), C-reactive protein (CRP) and polymorphonuclear elastase (PMNE). Ad- ditionally, leucocytes and lymphocytes counts in peripheral serum were also detected. Results: All the three groups showed a significant increase of the levels of IL-6, IL-8, CRP and PMNE after operation. There was no significant difference between D1 and D2 groups. When the comparison was made between D3 group and the other two groups, it showed higher concentration of IL-6, IL-8, CRP and PMNE in serum of D3 group. Leucocytes count showed no difference among the three groups. After operation, the patients in three groups had transient lymphocytes decrease on the second and third postoperative days, the lymphocytes count in D3 group was still lower while those in D1 and D2 groups began to increase. Conclusion: IL-6, IL-8, CRP and PMNE can be used to monitor surgical stress. Using these parameters, we found that extended lymph node dissec- tion of D3 group led to more postoperative stress than D1 and D2 groups.
文摘With the rise of digital transactions, e-Wallets have become prime targets for fraudulent activity. Early detection of suspicious transactions is therefore crucial to protect users and maintain trust in these systems. This article proposes a mathematical model based on a Mixed Integer Program (MIP) to identify and block suspicious transactions. This mathematical approach is designed to analyze e-Wallet transactions in real time by combining integer and continuous decision variables, offering greater flexibility in modeling fraud detection constraints. It considers parameters such as transaction cost, geographical location, type of device used for the transaction, IP address and other potential fraud indicators. Assigning suspicion scores to each transaction enables the model to identify risks that become habitual behavior and mark them as suspicious. Tests carried out on 10,000 digital transactions show that using PMNE significantly improves the detection of fraudulent transactions by identifying the most critical anomalies in terms of accuracy, adaptability and operational efficiency. The model also offers greater accuracy, reducing the number of false positives and false negatives, enabling faster intervention to block truly suspicious transactions.
