2025年9月10日,浙江大学良渚实验室、东部战区总医院国家肾脏疾病临床医学研究中心刘志红教授、俞晓敏研究员、周青教授团队在《自然》(Nature)杂志发表了题为“Loss-of-function mutations in PLD4 lead to systemic lupus erythemato...2025年9月10日,浙江大学良渚实验室、东部战区总医院国家肾脏疾病临床医学研究中心刘志红教授、俞晓敏研究员、周青教授团队在《自然》(Nature)杂志发表了题为“Loss-of-function mutations in PLD4 lead to systemic lupus erythematosus”论文(DOI:10.1038/s41586-025-09513-x),证实人类PLD4缺陷可导致系统性红斑狼疮(SLE)并阐明了其致病机制,为SLE的精准诊疗提供了重要的理论依据。展开更多
Tetravalent tin(Sn^(4+))-based inorganic perovskite semiconductors like Cs_(2)SnI_(6)are expected to replace lead-based perovskite counterparts due to advantages such as structural stability and environmental friendli...Tetravalent tin(Sn^(4+))-based inorganic perovskite semiconductors like Cs_(2)SnI_(6)are expected to replace lead-based perovskite counterparts due to advantages such as structural stability and environmental friendliness.In this paper,we reported the dopant compensation effect in the component-dependent self-doped(111)-oriented Cs_(2)SnI_(6)thin films grown with pulsed laser deposition(PLD)at room temperature.The films were grown on(100)-SrTiO_(3)(STO)substrates at room temperature by PLD.Hall results of the Cs_(2)SnI_(6)films with different components realizing by controlling the ratio of SnI_(4)/CsI in the targets demonstrate a clear change of conductivity type from N-type to P-type,while the carrier concentration decreases from 1018 to 1013 and accordingly the film resistivity increases significantly from 3.8 to 2506Ωcm.The defect-relatedopticalfingerprints of Cs_(2)SnI_(6)films werealsoinvestigated withtemperature-dependent photoluminescence spectroscopy.At low temperatures of 10 K,the Cs_(2)SnI_(6)films exhibit donor-bound(D^(0)X)and donor-acceptor pair(DAP)emission,respectively,due to the self-doping effect.These re-sults indicate that controlling the composition of the PLD target is a powerful way to tune the electrical properties of Cs_(2)SnI_(6)films for possible applications in solar cells or X-ray detectors.展开更多
文摘2025年9月10日,浙江大学良渚实验室、东部战区总医院国家肾脏疾病临床医学研究中心刘志红教授、俞晓敏研究员、周青教授团队在《自然》(Nature)杂志发表了题为“Loss-of-function mutations in PLD4 lead to systemic lupus erythematosus”论文(DOI:10.1038/s41586-025-09513-x),证实人类PLD4缺陷可导致系统性红斑狼疮(SLE)并阐明了其致病机制,为SLE的精准诊疗提供了重要的理论依据。
基金financially supported by the National Key Re-search and Development Program of China(No.2022YFC3700801)the Key R&D Program of Shandong Province,China(No.2024SFGC0102),the Jinan Bureau of Education(No.JNSX2023015)the Jinan Bureau of Science and Technology(No.202333042).
文摘Tetravalent tin(Sn^(4+))-based inorganic perovskite semiconductors like Cs_(2)SnI_(6)are expected to replace lead-based perovskite counterparts due to advantages such as structural stability and environmental friendliness.In this paper,we reported the dopant compensation effect in the component-dependent self-doped(111)-oriented Cs_(2)SnI_(6)thin films grown with pulsed laser deposition(PLD)at room temperature.The films were grown on(100)-SrTiO_(3)(STO)substrates at room temperature by PLD.Hall results of the Cs_(2)SnI_(6)films with different components realizing by controlling the ratio of SnI_(4)/CsI in the targets demonstrate a clear change of conductivity type from N-type to P-type,while the carrier concentration decreases from 1018 to 1013 and accordingly the film resistivity increases significantly from 3.8 to 2506Ωcm.The defect-relatedopticalfingerprints of Cs_(2)SnI_(6)films werealsoinvestigated withtemperature-dependent photoluminescence spectroscopy.At low temperatures of 10 K,the Cs_(2)SnI_(6)films exhibit donor-bound(D^(0)X)and donor-acceptor pair(DAP)emission,respectively,due to the self-doping effect.These re-sults indicate that controlling the composition of the PLD target is a powerful way to tune the electrical properties of Cs_(2)SnI_(6)films for possible applications in solar cells or X-ray detectors.
