AIM:To analyze the two-year visual and refractive outcomes as well as the safety,and efficacy of photorefractive keratectomy(PRK)surgery for myopia.METHODS:In this prospective cohort study,63 eligible patients were re...AIM:To analyze the two-year visual and refractive outcomes as well as the safety,and efficacy of photorefractive keratectomy(PRK)surgery for myopia.METHODS:In this prospective cohort study,63 eligible patients were recruited,including 45 women(71.4%)and 18 men(28.6%).Demographic characteristics along with pre-and post-operative clinical data including visual acuity,refraction,maximum ablation,spherical and cylindrical error,and residual stromal bed(RSB)were evaluated.RESULTS:The mean age of the patients was 35.42±8.16y(range 22 to 55y).The mean spherical and cylindrical error before surgery were-2.23±1.58 D(range-5 to+0.25)and-1.24±0.94 D,respectively(range-3.75 to 0.00).The mean efficacy and safety of PRK surgery at 2y follow-up were 0.98±0.06 and 1.01±0.04 respectively.The lower age was significantly correlated with a higher amount of efficacy index(P<0.001,r=-0.42).Also,the lower amount of preoperative myopia and spherical equivalent(SE)were correlated with a higher safety index(P<0.001,r=-0.44;P<0.001,r=-0.46).CONCLUSION:The two-year efficacy and safety of PRK for the treatment of low myopia is excellent.Younger age and lower amount of refractive error are correlated with higher efficacy and safety indices of the surgery.展开更多
This paper predicts that grey spatial solitons can exist in two-photon photorefractive materials. In steady state and undcr appropriate external bias conditions, it obtains the grey spatial soliton solutions of the op...This paper predicts that grey spatial solitons can exist in two-photon photorefractive materials. In steady state and undcr appropriate external bias conditions, it obtains the grey spatial soliton solutions of the optical wave evolution equation. The intensity profile, phase distribution, and transverse velocity of these grey solitons are discussed.展开更多
AIM:To investigate quantitative and qualitative optical outcomes of single-step transepithelial photorefractive keratectomy(Trans PRK)in high myopia.METHODS:In a prospective interventional case-series,30 eyes with hig...AIM:To investigate quantitative and qualitative optical outcomes of single-step transepithelial photorefractive keratectomy(Trans PRK)in high myopia.METHODS:In a prospective interventional case-series,30 eyes with high myopia(-6.00 to-8.75 D)with(up to-3.00 D)or without astigmatism were enrolled from Bina Eye Hospital,Tehran,Iran.One-step Trans PRK was performed with aberration-free aspherical optimized profile and SCHWIND AMARIS 500 laser.One-year follow-up results for refraction,visual acuities,vector analysis,ocular wavefront(OWF)and corneal wave-front(CWF)higher order aberrations(HOA),contrast sensitivity(CS),and postoperative haze were assessed.RESULTS:After the surgery,both photopic and mesopic CSs significantly improved(both P〈0.001).We detected significant induction of OWF coma and trefoil(P〈0.001 for both)HOAs;CWF coma(P=0.002),spherical(P〈0.001),and tetrafoil(P=0.003)HOAs in 6 mm analysis diameter;and CWF trefoil(P=0.04)HOA in 4 mm analysis diameter.The range of mean induction observed for various HOAs was0.005-0.11μm.The 86.7%of eyes reached an uncorrected distance visual acuity of 20/20 or better;96.7%of eyes were within±0.5 D of targeted spherical refraction.In vector analysis,mean correction index value was 1.03 and mean index of success was 0.22.By 12mo after the operation,no eye lost any number of corrected distancevisual acuity lines.We detected no corneal haze greater than 1~+throughout the follow-up.CONCLUSION:Our findings show promising effects of single-step Trans PRK on quality of vision in high myopic eyes.It also improves refraction and visual acuity.展开更多
AIM: To evaluate the results of three photorefractive keratectomy (PRK) procedures in the treatment of astigmatism. · METHODS: In this retrospective comparative case series, 89 eyes of 50 patients who underwent P...AIM: To evaluate the results of three photorefractive keratectomy (PRK) procedures in the treatment of astigmatism. · METHODS: In this retrospective comparative case series, 89 eyes of 50 patients who underwent PRK treatment for astigmatism were enrolled. The patients were divided into 3 groups based on the PRK procedure: Group 1: PRK without mitomycin -C (MMC) application, Group 2: PRK with MMC application, and Group 3: Trans-Photorefractive Keratectomy (T-PRK). The efficacy, safety, predictability, and complications of treatment were assessed at 1, 3 and 6 months after the treatment. ·RESULTS: At postoperative 6 months, the percentage of postoperative uncorrected visual acuity (UCVA) of 20/ 20 or better was 55.6% (20 eyes) in group 1, 75% (15 eyes) in group 2, and 75.8% (25 eyes) in group 3 (P = 0.144). The percentage of postoperative best corrected visual acuity (BCVA) of unchanged or gained ≥1 lines was 80.6% (29 eyes) in group 1, 70% (14 eyes) in group 2, and 90.9% (30 eyes) in group 3 (P =0.151). The percentage of postoperative BCVA of lost ≥2 lines was 11.1% (4 eyes) in group 1, 20% (4 eyes) in group 2, and 6.1% (2 eyes) in group 3. The mean manifest refractive spherical equivalent (MRSE) and mean cylindrical refraction were not significantly different among the each groups (P 】0.05). At postoperative 6 months, the percentage of MRSE of within ±0.50 D was 100% (36 eyes) in Group 1, 100% (20 eyes) in Group 2, and 93.9% (31 eyes) in Group 3. At the each follow-up period, there was no significant difference in number of eyes with haze and mean haze score(P】0.05). ·CONCLUSION: The study showed that PRK without MMC, PRK with MMC and T-PRK appears to have similareffectiveness, safety and predictability in the treatment of astigmatism. The incidence of haze was also similar between the three groups.展开更多
AIM: To evaluate postoperative pain, uncorrected visual acuity (UCVA), and cornea haze value after transepithelial photorefractive keratectomy (T-PRK) performed with aspherical ablation profile using SCHWIND ESIRIS ex...AIM: To evaluate postoperative pain, uncorrected visual acuity (UCVA), and cornea haze value after transepithelial photorefractive keratectomy (T-PRK) performed with aspherical ablation profile using SCHWIND ESIRIS excimer laser. METHODS: Retrospective case series. Fifty-nine eyes (32 patients) with myopia associated with or without astigmatism underwent phototherapeutic keratectomy (PTK) followed by photorefractive keratectomy (PRK) which performed by Optimized Refractive Keratecomy (ORK)-CAM software based on aspherical ablation profile using SCHWIND ESIRIS excimer laser. Postoperative pain scale was measured on a questionnaire through five levels. Haze was graded by five grades, and UCVA, manifest refraction spherical equivalent (MRSE) were analyzed. RESULTS: Mean pain level was (1.37 +/- 0.613) (range: 1 to 3), the mean time picking out the soft contact lens was (6.22 +/- 1.73) days, at 3 months, UCVA was 1.0 for 40 eyes (67.8%), 0.5 for all eyes (100.0%). The UCVA was significantly less than the preoperative best spectacle corrected visual acuity (BSCVA) (t=-2.84, P=0.006), haze value was (0.27 +/- 0.25), no patients had a haze grade up to 2. Mean MRSE was (0.76 +/- 0.96) diopter(D) by 3 months. CONCLUSION: The outcomes from this study show that using the SCHWIND ESIRIS aspherical ablation profile for transepithelial PRK has a good visual result. The primary advantage is related to a spherical ablation profile, automatically considers the ablation volume of the stroma and the accurate and smooth removal of the epithelium with PTK. Additional studies are needed to determine long-term outcomes.展开更多
AIM:To evaluate the efficacy and safety of the excimer laser correction of the residual refractive errors after cataract extraction with intraocular lens(IOL)implantation in uncommon cases.METHODS:Totally 24 patients ...AIM:To evaluate the efficacy and safety of the excimer laser correction of the residual refractive errors after cataract extraction with intraocular lens(IOL)implantation in uncommon cases.METHODS:Totally 24 patients with high residual refractive error after cataract surgery with IOL implantation were examined.Twenty-two patients had a history of phacoemulsification and IOL implantation,and two had extra-capsular cataract extraction with IOL implantation.Detailed examination of preoperative medical records was done to explain the origin of the post-cataract refractive errors.All patients underwent photorefractire keratectomy(PRK)enhancement.The mean outcome measures were refraction,uncorretted visual acuity(UCVA),best corrected visual acuity(BCVA)and corneal transparency and follow up ranged from 1 to 8 y.RESULTS:The principal causes of residual ametropia was inexact IOL calculation in abnormal eyes with high myopia and congenital lens abnormalities,followed by corneal astigmatism both suture induced and preexisting.After cataract surgery and before the laser enhancement the mean spherical equivalent(SE)was-0.56±3 D ranging from-4.62 to+2.25 D in high myopic patients,instead it was-1±1.73 D ranging from-3.25 to+3.75 D in the astigmatic eyes,with a mean cylinder of-3.75±0 ranging from-3 to+5.50 D.After laser refractive surgery the mean SE was 0.1±0.73,ranging from-0.50 to+1.50 in the myopic group,and it was-0.50±0.57 ranging from-1.25 to+0.50 in astigmatic patients,with a mean cylinder of-0.25±0.75.In myopic patients the mean UCVA and BCVA were 0.038±0.072 logMAR and 0.018±0.04 respectively,both ranging from 0.10 to 0.0.In astigmatic patients,the mean UCVA and BCVA were 0.213±0.132 and 0.00±0.0 respectively,UCVA ranging from 0.50 to 0.22 and BCVA was 0.00.All patients presented normal corneal transparency.No ocular hypertension was detected and no corneal haze was observed.All registered values remained stable also at the end line evaluation.CONCLUSION:The excimer laser treatment of residual refractive errors after cataract surgery with IOL implantation in abnormal eyes resulted in satisfactory and stable visual outcome with good safety and efficacy.展开更多
AIM: To determine risk factors of regression and undercorrection following photorefractive keratectomy (PRK) in myopia or myopic astigmatism. METHODS: A case -control study was designed in which eyes with an indicatio...AIM: To determine risk factors of regression and undercorrection following photorefractive keratectomy (PRK) in myopia or myopic astigmatism. METHODS: A case -control study was designed in which eyes with an indication for re-treatment (AT) were defined as cases; primary criteria for RT indication, as assessed at least 9mo postoperatively, included an uncorrected distance visual acuity (UDVA) of 20/30 or worse and a stable refraction for more than 3mo. Additional considerations included optical quality symptoms and significant higher order aberrations (HOAs). Controls were chosen from the same cohort of operated eyes which had complete post-operative follow up data beyond 9mo and did not need RT. The cohort included patients who had undergone PRK by the Tissue-Saving (TS) ablation profile of Technolas 217z100 excimer laser (Bausch & Lomb, Rochester, NY, USA). Mitomycin C had been used in all of the primary procedures. RESULTS: We had 70 case eyes and 158 control eyes, and they were comparable in terms of age, sex and follow -up time (P values: 0.58, 1.00 and 0.89, respectively). Pre-operative spherical equivalent of more than -5.00 diopter (D), intended optical zone (OZ) diameter of less than 6.00 mm and ocular fixation instability during laser ablation were associated with AT indications (all P values <0.001). These factors maintained their significance in the multiple logistic regression model with odd ratios of 6.12, 6.71 and 7.89, respectively. CONCLUSION: Higher refractive correction (>-5.00 D), smaller OZ (<6.00 mm) and unstable fixation during laser ablation of PRK for myopia and myopic astigmatism were found to be strong predictors of undercorrection and regression.展开更多
AIM: To evaluate the safety and efficacy of transepithelial photorefractive keratectomy(t-PRK) with adjuvant mitomycin C(MMC) versus femtosecond laser assisted keratomileusis(Femto-LASIK) in correction of high myopia....AIM: To evaluate the safety and efficacy of transepithelial photorefractive keratectomy(t-PRK) with adjuvant mitomycin C(MMC) versus femtosecond laser assisted keratomileusis(Femto-LASIK) in correction of high myopia.METHODS: Prospective randomized comparative study including 156 eyes of 156 patients with high myopia and a spherical equivalent refraction(SER) <-6.00 D. They were divided randomly into two groups: Group A included 72 eyes treated with t-PRK with adjuvant MMC and Group B included 84 eyes treated with Femto-LASIK. Visual acuity, SER, corneal topography, pachymetry and keratometry were assessed for 12 mo postoperatively.RESULTS: The preoperative mean SER was-8.86±1.81 and-9.25±1.70 D in t-PRK MMC group and Femto-LASIK respectively(P=0.99) which improved to-0.65±0.43 D and-0.69±0.50 D at 12 mo follow up. Mean SER remained stable during the 12 mo of follow-up, with no statistically significant difference between the two groups(P=0.64). In t-PRK MMC group, only six eyes needed retreatment after six months of follow up. And two eyes showed haze(one reversible haze grade 2, while the other had dense irreversible haze grade 4).CONCLUSION: t-PRK MMC provides safe and satisfactory visual outcomes and acceptable risk as Femto-LASIK in patients with high myopia.展开更多
AIM: To evaluate the long term clinical results of mechanical no-alcohol-assisted laser epithelial keratomileusis(LASEK) versus standard photorefractive keratectomy(PRK) for low-moderate myopia.METHODS: Twenty-five ey...AIM: To evaluate the long term clinical results of mechanical no-alcohol-assisted laser epithelial keratomileusis(LASEK) versus standard photorefractive keratectomy(PRK) for low-moderate myopia.METHODS: Twenty-five eyes treated with LASEK and twenty-five eyes treated with PRK were evaluated with a mean follow-up duration of 60 mo. Mechanical separation of the epithelium was performed with blunt spatula and without application of alcohol. Laser ablation was performed with the MEL-70 excimer laser. All patients were examined daily until epithelial closure; at 1, 3, 6,and 12 mo, and every year subsequently. Main outcome measures were uncorrected distance visual acuity(UDVA), corrected distance visual acuity(CDVA),manifest refraction, haze, efficacy and safety indexes.RESULTS: Twenty-one eyes and 22 eyes completed follow-up of 60 mo in LASEK and PRK group respectively. Manifest refraction at 60 mo follow-up was-0.01 and 0.26 in LASEK and PRK group respectively. In the LASEK group mean UDVA and mean CDVA after60 mo were 20/22 and 20/20 respectively(P 】0.01). In the PRK group mean UDVA and mean CDVA at 60 mo follow-up were 20/20 and 20/20 after 60mo(P 】0.01). The efficacy indexes were 0.87 and 0.95, and the safety indexes were1.25 and 1.4 respectively for LASEK group and PRK group.CONCLUSION: Both standard PRK and no-alcohol LASEK offer safe and effective correction of low-moderate myopia in the long term without any statistically significant difference between the two groups.展开更多
AIM:To investigate demographic and preoperative factors increasing the risk of ametropia following transepithelial photorefractive keratectomy(trans PRK)in myopia and myopic astigmatism.METHODS:This retrospective coho...AIM:To investigate demographic and preoperative factors increasing the risk of ametropia following transepithelial photorefractive keratectomy(trans PRK)in myopia and myopic astigmatism.METHODS:This retrospective cohort study included myopic eyes(-0.50 to-8.75 D)with or without astigmatism(up to 3.50 D)enrolled at Dr.Yap Eye Hospital Yogyakarta.Trans PRK was performed using Technolaz 217 z100 excimer laser.Subjects were clustered into ametropia and emmetropia group based on uncorrected distance visual acuities(UDVA)3 mo post-operatively.Multiple preoperative and intraoperative parameters were analyzed using Logistic regression to obtain their effect on ametropia risk following trans PRK.RESULTS:A total of 140 eyes of 87 consecutive subjects were studied.Prevalence of ametropia following trans PRK was 20(14.29%)eyes.Subjects in ametropia group were significantly older than the emmetropia group(31.80±14.23 vs 18.88±2.41,respectively;P<0.001).Bivariate Logistic regression analysis showed that older age(OR=1.23),higher preoperative spherical equivalent(>-6 D;OR=12.78),steeper anterior keratometric readings(Kmax>45 D and mean K>44 D;OR=4.28 and 4.35,respectively)increased the risk of ametropia following trans PRK.Adjusted multivariate Logistic regression analysis showed that age was the strongest predictor for the incidence of ametropia following trans PRK.Complications of trans PRK were overcorrection,suspected posterior keratoectasia and accommodation insuffiency.CONCLUSION:Older age can be the strongest factor for increasing ametropia risk following trans PRK.Cut-off points of Kmax and mean K at 45 and 44 D respectively are proposed as the predictors for ametropia following trans PRK.展开更多
We have grown triply doped Mg:Fe:Mn:LiTaO3 crystals with near stoichiometry using the top seeded solution growth technique. The defect structure was investigated by infrared absorption spectra and Curie temperature. U...We have grown triply doped Mg:Fe:Mn:LiTaO3 crystals with near stoichiometry using the top seeded solution growth technique. The defect structure was investigated by infrared absorption spectra and Curie temperature. Using a blue laser as the source, excellent photorefractive properties were obtained. Nonvolatile holographic storage properties were investigated using the dual wavelength technique. We got a very high fixed diffraction efficiency and nonvolatile holographic storage sensitivity. The blue light has more than enough energy to excite holes of deep(Mn) and shallow(Fe) trap centers with the same phase, which enhance dramatically the blue photorefractive properties and the nonvolatile holographic storage. Mg2+ ion is no longer damage resistant at blue laser, but enhances photorefractive characteristics.展开更多
Keratoconus and iatrogenic keratectasia are the corneal ectatic disorders occurring due to biomechanical weakening of the cornea resulting in distorted images,myopia, and irregular astigmatism. Corneal collagen cross-...Keratoconus and iatrogenic keratectasia are the corneal ectatic disorders occurring due to biomechanical weakening of the cornea resulting in distorted images,myopia, and irregular astigmatism. Corneal collagen cross-linking(CXL) is performed to arrest keratoconus successfully. The main aim of this review is to discuss the safety and efficacy of the adjuvant therapies, such as the combination of CXL and photorefractive keratectomy(PRK) for the treatment of corneal ectatic disorders. A comprehensive literature search was performed using PubM ed, MEDLINE, and Scopus using keywords ‘collagen’‘keratoconus’,‘keratectasia’,‘collagen cross-linking’,and ‘photorefractive keratectomy’. Search results were restricted to clinical studies published in English. Corneal CXL effectively arrests the progression of keratoconus by enhancing corneal rigidity. However, functional vision is not improved by cross-linking. Combining CXL to refractive surgeries such as topography-guided PRK or transepithelial PRK is found to be a safe and effective method in providing corneal stability as well as significantly improving functional visual acuity with few minor complications. This combined technique also prevents regression of keratoconus and reduce the risk of keratectasia. CXL combined with PRK is a promising therapeutic approach in ophthalmology that can be successfully used to treat progressive keratoconus and other corneal ectatic disorders and to enhance visual acuity.展开更多
We observed the photorefractive spatial dark-soliton stripes In LiNbO3:Fe crystal,and demonsirate the planar waveguide property of refractive index proiile induced by these spatial dark-soli ton stripes.We suggest a n...We observed the photorefractive spatial dark-soliton stripes In LiNbO3:Fe crystal,and demonsirate the planar waveguide property of refractive index proiile induced by these spatial dark-soli ton stripes.We suggest a new mothed to form the planar waveguide utilizing the grating fixing technique.展开更多
AIM:To evaluate the clinical results after implantation of a new intrastromal corneal ring segment(ICRS)associated with photorefractive keratectomy(PRK)to correct high myopia(HM)patients with thin corneas.METHODS:We e...AIM:To evaluate the clinical results after implantation of a new intrastromal corneal ring segment(ICRS)associated with photorefractive keratectomy(PRK)to correct high myopia(HM)patients with thin corneas.METHODS:We evaluated 42 eyes of 23 HM patients that had ICRS implantation followed by PRK.The mean age of patients was 29.1±7.12 y(range 18 to 40 years old).Uncorrected visual acuity(UCVA),best corrected visual acuity(BCVA),keratometry,spherical equivalent,pachymetry,and aberrometry were compared using ANOVA with repeated measurements evaluated preoperatively and at last follow-up visit after the procedures.The refractive predictability and simulated/real corneal ablation were also assessed.RESULTS:The mean follow-up time after PRK was 6.8±1.6 mo.The mean preoperative UCVA improved from 20/800 preoperative to 20/100 after ICRS and 20/35 after PRK.The mean preoperative BCVA was 20/25(range from 20/30 to 20/20)and remained unchanged after ICRS implantation.Following the PRK the mean BCVA was 20/25(range from 20/30 to 20/20).The mean spherical equivalent decreased from-7.25±1.12(range-5.00 to-9.00)preoperatively to-3.32±1.0(range-2.00 to-5.00)postoperatively(P<0.001)after ICRS implantation and decreased from-2.44±1.51 preoperatively to 0.32±0.45(range-0.625 to 0.875)postoperatively(P<0.001)after PRK.The change in BCVA and topographic astigmatism was statistically significant(P<0.0001).CONCLUSION:ICRS in HM associated with PRK can be a tissue saving procedure and an alternative surgical option for correction of moderate to high myopia.展开更多
The dynamical evolution of both signal and pump beams are traced by numerically solving the coupled-wave equation for a photorefractive two-wave mixing system. The direct simulations show that, when the intensity rati...The dynamical evolution of both signal and pump beams are traced by numerically solving the coupled-wave equation for a photorefractive two-wave mixing system. The direct simulations show that, when the intensity ratio of the pump beam to the signal beam is large enough, the pump beam presents a common decaying behaviour without modulational instability （MI）, while the signal beam can evolve into a quasistable spatial soliton within a regime in which the pump beam is depleted slightly. The larger the ratio is, the longer the regime is. Such quasistable solitons can overcome the initial perturbations and numerical noises in the course of propagation, perform several cycles of slow oscillation in intensity and width, and persist over tens of diffraction lengths. From physical viewpoints, these solitons actually exist as completely rigorous physical objects. If the ratio is quite small, the pump beam is apt to show MI, during which the signal beam experiences strong expansion and shrinking in width and a drastic oscillation in intensity, or completely breaks up. The simulations using actual experimental parameters demonstrate that the observation of an effectively stable soliton is quite possible in the proposed system.展开更多
It is shown theoretically that incoherently coupled bright-dark soliton pairs can exist in biased centrosymmetric photorefractive media under steady-state conditions. These soliton pairs can be established provided th...It is shown theoretically that incoherently coupled bright-dark soliton pairs can exist in biased centrosymmetric photorefractive media under steady-state conditions. These soliton pairs can be established provided that the two optical beams have the same polarization, wavelength, and are mutually incoherent.展开更多
A new method to suppress the fanning noise caused by He-Ne laser in the cooperation with Ar+laser in photorefractive LiNbO_(3):Fe crystal was successfully realized.This method is simple and efficient.By using this met...A new method to suppress the fanning noise caused by He-Ne laser in the cooperation with Ar+laser in photorefractive LiNbO_(3):Fe crystal was successfully realized.This method is simple and efficient.By using this method,fanning-noise-free hologram can be stored in LiNbO_(3):Fecrystal.展开更多
The incoherently coupled grey-grey screening-photovoltaic spatial soliton pairs are predicted in biased two-photon photovoltaic photorefractive crystals under steady-state conditions. These grey-grey screening-photovo...The incoherently coupled grey-grey screening-photovoltaic spatial soliton pairs are predicted in biased two-photon photovoltaic photorefractive crystals under steady-state conditions. These grey-grey screening-photovoltaic soliton pairs can be established provided that the incident beams have the same polarization, wavelength, and are mutually incoherent. The grey-grey screening-photovoltaic soliton pairs can be considered as the united form of grey- grey screening soliton pairs and open or closed-circuit grey-grey photovoltaic soliton pairs.展开更多
This paper investigates the photorefractive properties of iron doped lithium niobate with different [Li]/[Nb] ratios The experimental results show two photorefractive centres for iron doped near-stoichiometric lithium...This paper investigates the photorefractive properties of iron doped lithium niobate with different [Li]/[Nb] ratios The experimental results show two photorefractive centres for iron doped near-stoichiometric lithium niobate crystal Besides Fe^2＋ and Fe^3＋ ions, small polarons and bipolarons are considered as another photoactive centre.展开更多
The mechanism for the high-performance KNSBN:Cu crystal self-pumped phase-conjugator is first put forward in this letter as no-loop photorefractive self-bending succesive four-wave mixing interaction.And the photore f...The mechanism for the high-performance KNSBN:Cu crystal self-pumped phase-conjugator is first put forward in this letter as no-loop photorefractive self-bending succesive four-wave mixing interaction.And the photore fractive backscattering amplification was found to play a very important role in it.展开更多
文摘AIM:To analyze the two-year visual and refractive outcomes as well as the safety,and efficacy of photorefractive keratectomy(PRK)surgery for myopia.METHODS:In this prospective cohort study,63 eligible patients were recruited,including 45 women(71.4%)and 18 men(28.6%).Demographic characteristics along with pre-and post-operative clinical data including visual acuity,refraction,maximum ablation,spherical and cylindrical error,and residual stromal bed(RSB)were evaluated.RESULTS:The mean age of the patients was 35.42±8.16y(range 22 to 55y).The mean spherical and cylindrical error before surgery were-2.23±1.58 D(range-5 to+0.25)and-1.24±0.94 D,respectively(range-3.75 to 0.00).The mean efficacy and safety of PRK surgery at 2y follow-up were 0.98±0.06 and 1.01±0.04 respectively.The lower age was significantly correlated with a higher amount of efficacy index(P<0.001,r=-0.42).Also,the lower amount of preoperative myopia and spherical equivalent(SE)were correlated with a higher safety index(P<0.001,r=-0.44;P<0.001,r=-0.46).CONCLUSION:The two-year efficacy and safety of PRK for the treatment of low myopia is excellent.Younger age and lower amount of refractive error are correlated with higher efficacy and safety indices of the surgery.
基金Project supported by the National Natural Science Foundation of China （Grant No 60508005）, and Scientific Research Foundation of Harbin Institute of Technology of China （Grant No HIT. 2003. 31）.
文摘This paper predicts that grey spatial solitons can exist in two-photon photorefractive materials. In steady state and undcr appropriate external bias conditions, it obtains the grey spatial soliton solutions of the optical wave evolution equation. The intensity profile, phase distribution, and transverse velocity of these grey solitons are discussed.
文摘AIM:To investigate quantitative and qualitative optical outcomes of single-step transepithelial photorefractive keratectomy(Trans PRK)in high myopia.METHODS:In a prospective interventional case-series,30 eyes with high myopia(-6.00 to-8.75 D)with(up to-3.00 D)or without astigmatism were enrolled from Bina Eye Hospital,Tehran,Iran.One-step Trans PRK was performed with aberration-free aspherical optimized profile and SCHWIND AMARIS 500 laser.One-year follow-up results for refraction,visual acuities,vector analysis,ocular wavefront(OWF)and corneal wave-front(CWF)higher order aberrations(HOA),contrast sensitivity(CS),and postoperative haze were assessed.RESULTS:After the surgery,both photopic and mesopic CSs significantly improved(both P〈0.001).We detected significant induction of OWF coma and trefoil(P〈0.001 for both)HOAs;CWF coma(P=0.002),spherical(P〈0.001),and tetrafoil(P=0.003)HOAs in 6 mm analysis diameter;and CWF trefoil(P=0.04)HOA in 4 mm analysis diameter.The range of mean induction observed for various HOAs was0.005-0.11μm.The 86.7%of eyes reached an uncorrected distance visual acuity of 20/20 or better;96.7%of eyes were within±0.5 D of targeted spherical refraction.In vector analysis,mean correction index value was 1.03 and mean index of success was 0.22.By 12mo after the operation,no eye lost any number of corrected distancevisual acuity lines.We detected no corneal haze greater than 1~+throughout the follow-up.CONCLUSION:Our findings show promising effects of single-step Trans PRK on quality of vision in high myopic eyes.It also improves refraction and visual acuity.
文摘AIM: To evaluate the results of three photorefractive keratectomy (PRK) procedures in the treatment of astigmatism. · METHODS: In this retrospective comparative case series, 89 eyes of 50 patients who underwent PRK treatment for astigmatism were enrolled. The patients were divided into 3 groups based on the PRK procedure: Group 1: PRK without mitomycin -C (MMC) application, Group 2: PRK with MMC application, and Group 3: Trans-Photorefractive Keratectomy (T-PRK). The efficacy, safety, predictability, and complications of treatment were assessed at 1, 3 and 6 months after the treatment. ·RESULTS: At postoperative 6 months, the percentage of postoperative uncorrected visual acuity (UCVA) of 20/ 20 or better was 55.6% (20 eyes) in group 1, 75% (15 eyes) in group 2, and 75.8% (25 eyes) in group 3 (P = 0.144). The percentage of postoperative best corrected visual acuity (BCVA) of unchanged or gained ≥1 lines was 80.6% (29 eyes) in group 1, 70% (14 eyes) in group 2, and 90.9% (30 eyes) in group 3 (P =0.151). The percentage of postoperative BCVA of lost ≥2 lines was 11.1% (4 eyes) in group 1, 20% (4 eyes) in group 2, and 6.1% (2 eyes) in group 3. The mean manifest refractive spherical equivalent (MRSE) and mean cylindrical refraction were not significantly different among the each groups (P 】0.05). At postoperative 6 months, the percentage of MRSE of within ±0.50 D was 100% (36 eyes) in Group 1, 100% (20 eyes) in Group 2, and 93.9% (31 eyes) in Group 3. At the each follow-up period, there was no significant difference in number of eyes with haze and mean haze score(P】0.05). ·CONCLUSION: The study showed that PRK without MMC, PRK with MMC and T-PRK appears to have similareffectiveness, safety and predictability in the treatment of astigmatism. The incidence of haze was also similar between the three groups.
文摘AIM: To evaluate postoperative pain, uncorrected visual acuity (UCVA), and cornea haze value after transepithelial photorefractive keratectomy (T-PRK) performed with aspherical ablation profile using SCHWIND ESIRIS excimer laser. METHODS: Retrospective case series. Fifty-nine eyes (32 patients) with myopia associated with or without astigmatism underwent phototherapeutic keratectomy (PTK) followed by photorefractive keratectomy (PRK) which performed by Optimized Refractive Keratecomy (ORK)-CAM software based on aspherical ablation profile using SCHWIND ESIRIS excimer laser. Postoperative pain scale was measured on a questionnaire through five levels. Haze was graded by five grades, and UCVA, manifest refraction spherical equivalent (MRSE) were analyzed. RESULTS: Mean pain level was (1.37 +/- 0.613) (range: 1 to 3), the mean time picking out the soft contact lens was (6.22 +/- 1.73) days, at 3 months, UCVA was 1.0 for 40 eyes (67.8%), 0.5 for all eyes (100.0%). The UCVA was significantly less than the preoperative best spectacle corrected visual acuity (BSCVA) (t=-2.84, P=0.006), haze value was (0.27 +/- 0.25), no patients had a haze grade up to 2. Mean MRSE was (0.76 +/- 0.96) diopter(D) by 3 months. CONCLUSION: The outcomes from this study show that using the SCHWIND ESIRIS aspherical ablation profile for transepithelial PRK has a good visual result. The primary advantage is related to a spherical ablation profile, automatically considers the ablation volume of the stroma and the accurate and smooth removal of the epithelium with PTK. Additional studies are needed to determine long-term outcomes.
文摘AIM:To evaluate the efficacy and safety of the excimer laser correction of the residual refractive errors after cataract extraction with intraocular lens(IOL)implantation in uncommon cases.METHODS:Totally 24 patients with high residual refractive error after cataract surgery with IOL implantation were examined.Twenty-two patients had a history of phacoemulsification and IOL implantation,and two had extra-capsular cataract extraction with IOL implantation.Detailed examination of preoperative medical records was done to explain the origin of the post-cataract refractive errors.All patients underwent photorefractire keratectomy(PRK)enhancement.The mean outcome measures were refraction,uncorretted visual acuity(UCVA),best corrected visual acuity(BCVA)and corneal transparency and follow up ranged from 1 to 8 y.RESULTS:The principal causes of residual ametropia was inexact IOL calculation in abnormal eyes with high myopia and congenital lens abnormalities,followed by corneal astigmatism both suture induced and preexisting.After cataract surgery and before the laser enhancement the mean spherical equivalent(SE)was-0.56±3 D ranging from-4.62 to+2.25 D in high myopic patients,instead it was-1±1.73 D ranging from-3.25 to+3.75 D in the astigmatic eyes,with a mean cylinder of-3.75±0 ranging from-3 to+5.50 D.After laser refractive surgery the mean SE was 0.1±0.73,ranging from-0.50 to+1.50 in the myopic group,and it was-0.50±0.57 ranging from-1.25 to+0.50 in astigmatic patients,with a mean cylinder of-0.25±0.75.In myopic patients the mean UCVA and BCVA were 0.038±0.072 logMAR and 0.018±0.04 respectively,both ranging from 0.10 to 0.0.In astigmatic patients,the mean UCVA and BCVA were 0.213±0.132 and 0.00±0.0 respectively,UCVA ranging from 0.50 to 0.22 and BCVA was 0.00.All patients presented normal corneal transparency.No ocular hypertension was detected and no corneal haze was observed.All registered values remained stable also at the end line evaluation.CONCLUSION:The excimer laser treatment of residual refractive errors after cataract surgery with IOL implantation in abnormal eyes resulted in satisfactory and stable visual outcome with good safety and efficacy.
文摘AIM: To determine risk factors of regression and undercorrection following photorefractive keratectomy (PRK) in myopia or myopic astigmatism. METHODS: A case -control study was designed in which eyes with an indication for re-treatment (AT) were defined as cases; primary criteria for RT indication, as assessed at least 9mo postoperatively, included an uncorrected distance visual acuity (UDVA) of 20/30 or worse and a stable refraction for more than 3mo. Additional considerations included optical quality symptoms and significant higher order aberrations (HOAs). Controls were chosen from the same cohort of operated eyes which had complete post-operative follow up data beyond 9mo and did not need RT. The cohort included patients who had undergone PRK by the Tissue-Saving (TS) ablation profile of Technolas 217z100 excimer laser (Bausch & Lomb, Rochester, NY, USA). Mitomycin C had been used in all of the primary procedures. RESULTS: We had 70 case eyes and 158 control eyes, and they were comparable in terms of age, sex and follow -up time (P values: 0.58, 1.00 and 0.89, respectively). Pre-operative spherical equivalent of more than -5.00 diopter (D), intended optical zone (OZ) diameter of less than 6.00 mm and ocular fixation instability during laser ablation were associated with AT indications (all P values <0.001). These factors maintained their significance in the multiple logistic regression model with odd ratios of 6.12, 6.71 and 7.89, respectively. CONCLUSION: Higher refractive correction (>-5.00 D), smaller OZ (<6.00 mm) and unstable fixation during laser ablation of PRK for myopia and myopic astigmatism were found to be strong predictors of undercorrection and regression.
文摘AIM: To evaluate the safety and efficacy of transepithelial photorefractive keratectomy(t-PRK) with adjuvant mitomycin C(MMC) versus femtosecond laser assisted keratomileusis(Femto-LASIK) in correction of high myopia.METHODS: Prospective randomized comparative study including 156 eyes of 156 patients with high myopia and a spherical equivalent refraction(SER) <-6.00 D. They were divided randomly into two groups: Group A included 72 eyes treated with t-PRK with adjuvant MMC and Group B included 84 eyes treated with Femto-LASIK. Visual acuity, SER, corneal topography, pachymetry and keratometry were assessed for 12 mo postoperatively.RESULTS: The preoperative mean SER was-8.86±1.81 and-9.25±1.70 D in t-PRK MMC group and Femto-LASIK respectively(P=0.99) which improved to-0.65±0.43 D and-0.69±0.50 D at 12 mo follow up. Mean SER remained stable during the 12 mo of follow-up, with no statistically significant difference between the two groups(P=0.64). In t-PRK MMC group, only six eyes needed retreatment after six months of follow up. And two eyes showed haze(one reversible haze grade 2, while the other had dense irreversible haze grade 4).CONCLUSION: t-PRK MMC provides safe and satisfactory visual outcomes and acceptable risk as Femto-LASIK in patients with high myopia.
文摘AIM: To evaluate the long term clinical results of mechanical no-alcohol-assisted laser epithelial keratomileusis(LASEK) versus standard photorefractive keratectomy(PRK) for low-moderate myopia.METHODS: Twenty-five eyes treated with LASEK and twenty-five eyes treated with PRK were evaluated with a mean follow-up duration of 60 mo. Mechanical separation of the epithelium was performed with blunt spatula and without application of alcohol. Laser ablation was performed with the MEL-70 excimer laser. All patients were examined daily until epithelial closure; at 1, 3, 6,and 12 mo, and every year subsequently. Main outcome measures were uncorrected distance visual acuity(UDVA), corrected distance visual acuity(CDVA),manifest refraction, haze, efficacy and safety indexes.RESULTS: Twenty-one eyes and 22 eyes completed follow-up of 60 mo in LASEK and PRK group respectively. Manifest refraction at 60 mo follow-up was-0.01 and 0.26 in LASEK and PRK group respectively. In the LASEK group mean UDVA and mean CDVA after60 mo were 20/22 and 20/20 respectively(P 】0.01). In the PRK group mean UDVA and mean CDVA at 60 mo follow-up were 20/20 and 20/20 after 60mo(P 】0.01). The efficacy indexes were 0.87 and 0.95, and the safety indexes were1.25 and 1.4 respectively for LASEK group and PRK group.CONCLUSION: Both standard PRK and no-alcohol LASEK offer safe and effective correction of low-moderate myopia in the long term without any statistically significant difference between the two groups.
文摘AIM:To investigate demographic and preoperative factors increasing the risk of ametropia following transepithelial photorefractive keratectomy(trans PRK)in myopia and myopic astigmatism.METHODS:This retrospective cohort study included myopic eyes(-0.50 to-8.75 D)with or without astigmatism(up to 3.50 D)enrolled at Dr.Yap Eye Hospital Yogyakarta.Trans PRK was performed using Technolaz 217 z100 excimer laser.Subjects were clustered into ametropia and emmetropia group based on uncorrected distance visual acuities(UDVA)3 mo post-operatively.Multiple preoperative and intraoperative parameters were analyzed using Logistic regression to obtain their effect on ametropia risk following trans PRK.RESULTS:A total of 140 eyes of 87 consecutive subjects were studied.Prevalence of ametropia following trans PRK was 20(14.29%)eyes.Subjects in ametropia group were significantly older than the emmetropia group(31.80±14.23 vs 18.88±2.41,respectively;P<0.001).Bivariate Logistic regression analysis showed that older age(OR=1.23),higher preoperative spherical equivalent(>-6 D;OR=12.78),steeper anterior keratometric readings(Kmax>45 D and mean K>44 D;OR=4.28 and 4.35,respectively)increased the risk of ametropia following trans PRK.Adjusted multivariate Logistic regression analysis showed that age was the strongest predictor for the incidence of ametropia following trans PRK.Complications of trans PRK were overcorrection,suspected posterior keratoectasia and accommodation insuffiency.CONCLUSION:Older age can be the strongest factor for increasing ametropia risk following trans PRK.Cut-off points of Kmax and mean K at 45 and 44 D respectively are proposed as the predictors for ametropia following trans PRK.
基金Project supported by the National Natural Science Foundation of China （Grant No. 51202045）, the Postdoctoral Science Foundation of Heilongjiang Province, China, and the Fundamental Research Funds for the Central Universities of Ministry of Education of China （Grant No. HIT. NSRIF. 2013004）.
文摘We have grown triply doped Mg:Fe:Mn:LiTaO3 crystals with near stoichiometry using the top seeded solution growth technique. The defect structure was investigated by infrared absorption spectra and Curie temperature. Using a blue laser as the source, excellent photorefractive properties were obtained. Nonvolatile holographic storage properties were investigated using the dual wavelength technique. We got a very high fixed diffraction efficiency and nonvolatile holographic storage sensitivity. The blue light has more than enough energy to excite holes of deep(Mn) and shallow(Fe) trap centers with the same phase, which enhance dramatically the blue photorefractive properties and the nonvolatile holographic storage. Mg2+ ion is no longer damage resistant at blue laser, but enhances photorefractive characteristics.
文摘Keratoconus and iatrogenic keratectasia are the corneal ectatic disorders occurring due to biomechanical weakening of the cornea resulting in distorted images,myopia, and irregular astigmatism. Corneal collagen cross-linking(CXL) is performed to arrest keratoconus successfully. The main aim of this review is to discuss the safety and efficacy of the adjuvant therapies, such as the combination of CXL and photorefractive keratectomy(PRK) for the treatment of corneal ectatic disorders. A comprehensive literature search was performed using PubM ed, MEDLINE, and Scopus using keywords ‘collagen’‘keratoconus’,‘keratectasia’,‘collagen cross-linking’,and ‘photorefractive keratectomy’. Search results were restricted to clinical studies published in English. Corneal CXL effectively arrests the progression of keratoconus by enhancing corneal rigidity. However, functional vision is not improved by cross-linking. Combining CXL to refractive surgeries such as topography-guided PRK or transepithelial PRK is found to be a safe and effective method in providing corneal stability as well as significantly improving functional visual acuity with few minor complications. This combined technique also prevents regression of keratoconus and reduce the risk of keratectasia. CXL combined with PRK is a promising therapeutic approach in ophthalmology that can be successfully used to treat progressive keratoconus and other corneal ectatic disorders and to enhance visual acuity.
基金Supported by the Third World Academy of Sciencesthe National Natural Science Foundation of Cliinathe Key Research Project in Climbing Program from the State Science and Technology Commission of China.
文摘We observed the photorefractive spatial dark-soliton stripes In LiNbO3:Fe crystal,and demonsirate the planar waveguide property of refractive index proiile induced by these spatial dark-soli ton stripes.We suggest a new mothed to form the planar waveguide utilizing the grating fixing technique.
文摘AIM:To evaluate the clinical results after implantation of a new intrastromal corneal ring segment(ICRS)associated with photorefractive keratectomy(PRK)to correct high myopia(HM)patients with thin corneas.METHODS:We evaluated 42 eyes of 23 HM patients that had ICRS implantation followed by PRK.The mean age of patients was 29.1±7.12 y(range 18 to 40 years old).Uncorrected visual acuity(UCVA),best corrected visual acuity(BCVA),keratometry,spherical equivalent,pachymetry,and aberrometry were compared using ANOVA with repeated measurements evaluated preoperatively and at last follow-up visit after the procedures.The refractive predictability and simulated/real corneal ablation were also assessed.RESULTS:The mean follow-up time after PRK was 6.8±1.6 mo.The mean preoperative UCVA improved from 20/800 preoperative to 20/100 after ICRS and 20/35 after PRK.The mean preoperative BCVA was 20/25(range from 20/30 to 20/20)and remained unchanged after ICRS implantation.Following the PRK the mean BCVA was 20/25(range from 20/30 to 20/20).The mean spherical equivalent decreased from-7.25±1.12(range-5.00 to-9.00)preoperatively to-3.32±1.0(range-2.00 to-5.00)postoperatively(P<0.001)after ICRS implantation and decreased from-2.44±1.51 preoperatively to 0.32±0.45(range-0.625 to 0.875)postoperatively(P<0.001)after PRK.The change in BCVA and topographic astigmatism was statistically significant(P<0.0001).CONCLUSION:ICRS in HM associated with PRK can be a tissue saving procedure and an alternative surgical option for correction of moderate to high myopia.
基金Project supported by the National Natural Science Foundation of China （Grant Nos 10574051 and 10174025）.
文摘The dynamical evolution of both signal and pump beams are traced by numerically solving the coupled-wave equation for a photorefractive two-wave mixing system. The direct simulations show that, when the intensity ratio of the pump beam to the signal beam is large enough, the pump beam presents a common decaying behaviour without modulational instability （MI）, while the signal beam can evolve into a quasistable spatial soliton within a regime in which the pump beam is depleted slightly. The larger the ratio is, the longer the regime is. Such quasistable solitons can overcome the initial perturbations and numerical noises in the course of propagation, perform several cycles of slow oscillation in intensity and width, and persist over tens of diffraction lengths. From physical viewpoints, these solitons actually exist as completely rigorous physical objects. If the ratio is quite small, the pump beam is apt to show MI, during which the signal beam experiences strong expansion and shrinking in width and a drastic oscillation in intensity, or completely breaks up. The simulations using actual experimental parameters demonstrate that the observation of an effectively stable soliton is quite possible in the proposed system.
基金Supported by the China Postdoctoral Science Foundation。
文摘It is shown theoretically that incoherently coupled bright-dark soliton pairs can exist in biased centrosymmetric photorefractive media under steady-state conditions. These soliton pairs can be established provided that the two optical beams have the same polarization, wavelength, and are mutually incoherent.
基金Supported by the National Natural Science Foundation of China,and the National Climbing Programme of Fundamental Research。
文摘A new method to suppress the fanning noise caused by He-Ne laser in the cooperation with Ar+laser in photorefractive LiNbO_(3):Fe crystal was successfully realized.This method is simple and efficient.By using this method,fanning-noise-free hologram can be stored in LiNbO_(3):Fecrystal.
基金Supported by the Science and Technology Development Foundation of Higher Education of Shanxi Province under Grant No. 200611042
文摘The incoherently coupled grey-grey screening-photovoltaic spatial soliton pairs are predicted in biased two-photon photovoltaic photorefractive crystals under steady-state conditions. These grey-grey screening-photovoltaic soliton pairs can be established provided that the incident beams have the same polarization, wavelength, and are mutually incoherent. The grey-grey screening-photovoltaic soliton pairs can be considered as the united form of grey- grey screening soliton pairs and open or closed-circuit grey-grey photovoltaic soliton pairs.
基金Project supported by the research funding via Program for Changjiang Scholars of ChinaInnovative Research Team in University,China+1 种基金the National Natural Science Foundation of China(Grant No60578019)Program for Changjiang Scholars and Innovative Research Team in University
文摘This paper investigates the photorefractive properties of iron doped lithium niobate with different [Li]/[Nb] ratios The experimental results show two photorefractive centres for iron doped near-stoichiometric lithium niobate crystal Besides Fe^2＋ and Fe^3＋ ions, small polarons and bipolarons are considered as another photoactive centre.
基金Supported by the National Natural Science Foundation of ChinaTianjin Science Foundation for Youth.
文摘The mechanism for the high-performance KNSBN:Cu crystal self-pumped phase-conjugator is first put forward in this letter as no-loop photorefractive self-bending succesive four-wave mixing interaction.And the photore fractive backscattering amplification was found to play a very important role in it.
