以ZIF-8为碳源,通过高温热解的方法,制备了一种非贵金属氧还原反应(ORR)催化剂—碳包覆的Fe-P复合材料(Fe-P@CMF).实验结果表明,当烧结温度为1100℃时,复合材料Fe-P@CMF-1100的ORR性能最佳,在O 2饱和的0.1 M KOH中,其起始电位达到了0.94...以ZIF-8为碳源,通过高温热解的方法,制备了一种非贵金属氧还原反应(ORR)催化剂—碳包覆的Fe-P复合材料(Fe-P@CMF).实验结果表明,当烧结温度为1100℃时,复合材料Fe-P@CMF-1100的ORR性能最佳,在O 2饱和的0.1 M KOH中,其起始电位达到了0.94 V,半波电位达到了0.85 V.K-L曲线的结果表明,复合材料Fe-P@CMF-1100催化ORR遵循四电子转移机理.此外,Fe-P@CMF-1100比Pt/C具有更高的电催化稳定性,在经历10 h的稳定性测试之后,电流密度依然保持了初始值的89.4%;同时,该复合材料比Pt/C具有更好的甲醇耐受性.本研究为废弃磷铁资源的二次利用开辟了新途径,对于提高能源的转化效率和实现环境资源的可持续发展有着重要的意义.展开更多
Burns are a common medical problem globally,and wound infection is one of the major causes of inducing related complications.Although antibiotics effectively prevent wound infections,the misuse of antibiotics has crea...Burns are a common medical problem globally,and wound infection is one of the major causes of inducing related complications.Although antibiotics effectively prevent wound infections,the misuse of antibiotics has created a new problem of superbugs.Herein,we propose a new strategy to obtain pH-responsive antimicrobial P-ZIF(ZIF:zeolitic imidazolate framework)by loading polyhexamethylenebiguanide(PHMB)into the framework of ZIF-8 nanoparticles.This will enable PHMB to be released in the weak acid environment of an infected wound.To address burn infections,P-ZIF nanoparticles were loaded into a hydrogel system made of sodium alginate(SA)and 3-aminophenylboronic acid modified human-like collagen(H-A)through borate ester bonds.The resulting H-A/SA/P-ZIF(HASPZ)hydrogel dressing not only possesses antibacterial and wound healing properties but also has dual pH responsiveness to prevent the overuse of medication while effectively treat deep second-degree burns.Therefore,P-ZIF nanoparticles and the corresponding HASPZ hydrogel dressing are considered of significant importance in antimicrobial,drug delivery,and wound repair.展开更多
基金supported by the National key Research and Development Program of China(Nos.2021YFC2101504,2021YFC2103900,and 2019YFA0905200)the National Natural Science Foundation of China(Nos.22078265 and 21908179)the Natural Science Foundation of Shaanxi Province,China(No.218JQ2052).
文摘Burns are a common medical problem globally,and wound infection is one of the major causes of inducing related complications.Although antibiotics effectively prevent wound infections,the misuse of antibiotics has created a new problem of superbugs.Herein,we propose a new strategy to obtain pH-responsive antimicrobial P-ZIF(ZIF:zeolitic imidazolate framework)by loading polyhexamethylenebiguanide(PHMB)into the framework of ZIF-8 nanoparticles.This will enable PHMB to be released in the weak acid environment of an infected wound.To address burn infections,P-ZIF nanoparticles were loaded into a hydrogel system made of sodium alginate(SA)and 3-aminophenylboronic acid modified human-like collagen(H-A)through borate ester bonds.The resulting H-A/SA/P-ZIF(HASPZ)hydrogel dressing not only possesses antibacterial and wound healing properties but also has dual pH responsiveness to prevent the overuse of medication while effectively treat deep second-degree burns.Therefore,P-ZIF nanoparticles and the corresponding HASPZ hydrogel dressing are considered of significant importance in antimicrobial,drug delivery,and wound repair.
