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P-Δ effect on inelastic displacement ratio spectra for inelastic structures 被引量:3
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作者 翟长海 李宁 +1 位作者 马玉宏 谢礼立 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2011年第1期107-112,共6页
For the evaluation of structures with known ductility demands,the constant-ductility displacement ratio spectra(CDDRS) are particularly useful for providing inelastic displacement ratios to estimate maximum lateral in... For the evaluation of structures with known ductility demands,the constant-ductility displacement ratio spectra(CDDRS) are particularly useful for providing inelastic displacement ratios to estimate maximum lateral inelastic displacement demands from maximum elastic displacement demands.The CDDRS are computed for single-degree-of-freedom systems(SDOF) by considering or ignoring P-Δ effect for different ductility levels when subjected to 344 earthquake ground motions recorded in four site classes.The modified expressions of CDDRS for P-Δ effect are proposed.It is concluded that the P-Δ effect on CDDRS is significant,and the effect increases with the increase of ductility level.In the long-period region,the CDDRS ignoring P-Δ effect almost conforms to the equal-displacement rule.But in the case of higher ductility level,the CDDRS considering P-Δ effect are much higher than 1.0,which do not conform to the equal-displacement rule. 展开更多
关键词 constant-ductility displacement ratio spectra inelastic displacement estimation p-Δ effect ductility level structural periods
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Static and dynamic inelastic P-Δ effect for seismic design
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作者 Li Xiao Tong Genshu 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2021年第3期645-660,共16页
Seismic influence of P-Δ effect is the subject of this study.First,it is pointed out that the elastic static amplification factor shall be isolated in formulating the dynamic inelastic second order effect.An amplific... Seismic influence of P-Δ effect is the subject of this study.First,it is pointed out that the elastic static amplification factor shall be isolated in formulating the dynamic inelastic second order effect.An amplification factor for the static inelastic P-Δ effect is derived.Seismic force reduction factors(SFRF)for given ductility and stability coefficients are computed for one-story,one-span frames.The P-Δ amplification factors for seismic base shears are obtained by dividing SFRFs with and without P-Δ effect.Both P-Δ amplification factors and SFRFs are presented separately with two kinds of period abscissas.The P-Δ amplification factors are dependent on periods with the maximum occurring at about 0.75 s for site type C and approach to the static inelastic counterpart at long periods.Post-yield stiffness cannot fully counteract the adverse impact of the P-Δ effect.Formulas for seismic P-Δ amplification factors are proposed and compared to results of others.Collapse capacity spectra(CCS)are reviewed and their application in codes discussed.Available CCSs are compared with SFRFs with finite ductility computed for two ensembles of seismic records.A comparison reveals that the SFRFs are affected by seismic records,and available CCSs do not always provide upper limits for the SFRFs when stability coefficients are greater than 0.1 for frame models. 展开更多
关键词 seismic force reduction factor p-Δeffect amplification factor dynamic stability characteristic period
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Displacement damage effects on the p-GaN HEMT induced by neutrons at Back-n in the China Spallation Neutron Source
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作者 Yu-Fei Liu Li-Li Ding +3 位作者 Yuan-Yuan Xue Shu-Xuan Zhang Wei Chen Yong-Tao Zhao 《Chinese Physics B》 2025年第10期475-480,共6页
Irradiation experiments on p-Ga N gate high-electron-mobility transistors(HEMTs) were conducted using neutrons at Back-streaming White Neutron(Back-n) facility at the China Spallation Neutron Source(CSNS).Two groups o... Irradiation experiments on p-Ga N gate high-electron-mobility transistors(HEMTs) were conducted using neutrons at Back-streaming White Neutron(Back-n) facility at the China Spallation Neutron Source(CSNS).Two groups of devices were float-biased,while one group was ON-biased.Post-irradiation analysis revealed that the electrical performance of the devices exhibited progressive degradation with increasing Back-n fluence,with the ON-biased group demonstrating the most pronounced deterioration.This degradation was primarily characterized by a negative shift in the threshold voltage,a significant increase in reverse gate leakage current,and a slight reduction in forward gate leakage.Further analysis of the gate leakage current and capacitance-voltage characteristics indicated an elevated concentration of two-dimensional electron gas(2DEG),attributed to donor-type defects introduced within the barrier layer by Back-n irradiation.These defects act as hole traps,converting into fixed positive charges that deepen the quantum-well conduction band,thereby enhancing the 2DEG density.Additionally,through the trap-assisted tunneling mechanism,these defects serve as tunneling centers,increasing the probability of electron tunneling and consequently elevating the reverse gate leakage current. 展开更多
关键词 displacement damage effects HEMT Back-n CSNS threshold voltage shift
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Evaluation of scale effects in physical modeling of combined ogee and sharp-crested weir flow using a 3D CFD model
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作者 James Zulfan Bobby Minola Ginting Ravi Anthony Tartandyo 《Water Science and Engineering》 2025年第2期225-235,共11页
Research on scale effects on flows over weirs has been conducted on a limited basis, primarily focusing on flows upstream of a single-type weir, such as ogee, broad-crested, and sharp-crested (linear and non-linear) w... Research on scale effects on flows over weirs has been conducted on a limited basis, primarily focusing on flows upstream of a single-type weir, such as ogee, broad-crested, and sharp-crested (linear and non-linear) weirs. However, the scale effects downstream of these single-type weirs have not been thoroughly investigated. This study examined the scale effects on flows over a combined weir system consisting of an ogee weir and a sharp-crested weir, both upstream and downstream, utilizing physical modeling at a 1:33.33 scale based on Froude similarity and three-dimensional (3D) computational fluid dynamics (CFD) modeling. The sharp-crested weir in this study was represented by two sluice gates that remain closed and submerged during flood events. The experimental data confirmed that the equivalent discharge coefficients of the combined weir system behaved similarly to those of a sharp-crested weir across various H/P (where H is the total head, and P is the weir height) values. However, scale effects on the discharge rating curve due to surface tension and viscosity could only be minimized when H/P > 0.4, Re > 26 959, and We > 240 (where Re and We are the Reynolds and Weber numbers, respectively), provided that the water depth exceeded 0.042 m above the crest. Additionally, Re greater than 4 × 104 was necessary to minimize scale effects caused by viscosity in flows in the spillway channel and stilling basin (with baffle blocks). The limiting criteria aligned closely with existing literature. This study offers valuable insights for practical applications in hydraulic engineering in the future. 展开更多
关键词 3D CFD Ogee weir Physical modeling Sharp-crested weir Sluice gate Scale effects
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Improving electrical performance and fringe effect in p-type SnO_(x)thin film transistors via Ta incorporation
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作者 Yu Song Runtong Guo +6 位作者 Ruohao Hong Rui He Xuming Zou Benjamin Iñiguez Denis Flandre Lei Liao Guoli Li 《Journal of Semiconductors》 2025年第9期78-85,共8页
In this work,the incorporation of tantalum(Ta)into p-type metal-oxide(SnO_(x))semiconductor film is investigated to improve the electrical characteristics and suppress the fringe effect of thin film transistors(TFTs).... In this work,the incorporation of tantalum(Ta)into p-type metal-oxide(SnO_(x))semiconductor film is investigated to improve the electrical characteristics and suppress the fringe effect of thin film transistors(TFTs).The Ta-doped SnO_(x)(SnO_(x):Ta)film is deposited by radio-frequency(RF)magnetron sputtering with a Sn:Ta(3 at.%)target and thermally annealed at 270℃ for 30 min.Here,we observe that the SnO_(x):Ta film presents increased crystallinity,reduced defect density(3.25×10^(12)cm^(−2)·eV^(−1)),and widened bandgap(1.98 eV),in comparison with the undoped SnO_(x)film.As a result,the SnO_(x):Ta TFTs exhibit a lower off-state current(Ioff),an improved on/off current ratio(2.17×10^(4)),a remarkably decreased subthreshold swing(SS)by 41%,and enhanced device stability.Additionally,by introducing Ta dopants,the fringe effect as well as the impact of channel width-to-length ratio(W/L)on electrical performances of the p-type oxide TFTs can be effectively suppressed.These results shall contribute to further exploration and development of p-type SnO_(x)TFTs. 展开更多
关键词 tin monoxide p-type thin film transistors Ta doping fringe effect on/off current ratio
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Electronically Conductive Metal−Organic Framework With Photoelectric and Photothermal Effect as a Stable Cathode for High-Temperature Photo-Assisted Zn/Sn-Air Battery
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作者 Jiangchang Chen Chuntao Yang +2 位作者 Yao Dong Ya Han Yingjian 《Carbon Energy》 2026年第1期105-114,共10页
Rechargeable Zn/Sn-air batteries have received considerable attention as promising energy storage devices.However,the electrochemical performance of these batteries is significantly constrained by the sluggish electro... Rechargeable Zn/Sn-air batteries have received considerable attention as promising energy storage devices.However,the electrochemical performance of these batteries is significantly constrained by the sluggish electrocatalytic reaction kinetics at the cathode.The integration of light energy into Zn/Sn-air batteries is a promising strategy for enhancing their performance.However,the photothermal and photoelectric effects generate heat in the battery under prolonged solar irradiation,leading to air cathode instability.This paper presents the first design and synthesis of Ni_(2)-1,5-diamino-4,8-dihydroxyanthraquinone(Ni_(2)DDA),an electronically conductiveπ-d conjugated metal-organic framework(MOF).Ni_(2)DDA exhibits both photoelectric and photothermal effects,with an optical band gap of~1.14 eV.Under illumination,Ni_(2)DDA achieves excellent oxygen evolution reaction performance(with an overpotential of 245 mV vs.reversible hydrogen electrode at 10 mA cm^(−2))and photothermal stability.These properties result from the synergy between the photoelectric and photothermal effects of Ni_(2)DDA.Upon integration into Zn/Sn-air batteries,Ni_(2)DDA ensures excellent cycling stability under light and exhibits remarkable performance in high-temperature environments up to 80℃.This study experimentally confirms the stable operation of photo-assisted Zn/Sn-air batteries under high-temperature conditions for the first time and provides novel insights into the application of electronically conductive MOFs in photoelectrocatalysis and photothermal catalysis. 展开更多
关键词 electronically conductive MOFs high temperatures photo-assisted Zn/Sn-air batteries photoelectric effects photothermal effects
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CUDA‑based GPU‑only computation for efficient tracking simulation of single and multi‑bunch collective effects
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作者 Keon Hee Kim Eun‑San Kim 《Nuclear Science and Techniques》 2026年第1期61-79,共19页
Beam-tracking simulations have been extensively utilized in the study of collective beam instabilities in circular accelerators.Traditionally,many simulation codes have relied on central processing unit(CPU)-based met... Beam-tracking simulations have been extensively utilized in the study of collective beam instabilities in circular accelerators.Traditionally,many simulation codes have relied on central processing unit(CPU)-based methods,tracking on a single CPU core,or parallelizing the computation across multiple cores via the message passing interface(MPI).Although these approaches work well for single-bunch tracking,scaling them to multiple bunches significantly increases the computational load,which often necessitates the use of a dedicated multi-CPU cluster.To address this challenge,alternative methods leveraging General-Purpose computing on Graphics Processing Units(GPGPU)have been proposed,enabling tracking studies on a standalone desktop personal computer(PC).However,frequent CPU-GPU interactions,including data transfers and synchronization operations during tracking,can introduce communication overheads,potentially reducing the overall effectiveness of GPU-based computations.In this study,we propose a novel approach that eliminates this overhead by performing the entire tracking simulation process exclusively on the GPU,thereby enabling the simultaneous processing of all bunches and their macro-particles.Specifically,we introduce MBTRACK2-CUDA,a Compute Unified Device Architecture(CUDA)ported version of MBTRACK2,which facilitates efficient tracking of single-and multi-bunch collective effects by leveraging the full GPU-resident computation. 展开更多
关键词 Code development GPU computing Collective effects
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Synergistic antibacterial effect and mechanism of benzalkonium chloride and polymyxin B against Pseudomonas aeruginosa
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作者 Caihong Wang Jiaxin Zhang +3 位作者 Tong Li Jingwei Wang Dan Xu Qiao Ma 《Journal of Environmental Sciences》 2026年第1期555-564,共10页
Benzalkonium chloride(BAC)is widely employed as a broad-spectrum biocide and has emerged as a significant environmental pollutant.Polymyxin B(PB)serves as the last-line defense for the treatment of Gram-negative patho... Benzalkonium chloride(BAC)is widely employed as a broad-spectrum biocide and has emerged as a significant environmental pollutant.Polymyxin B(PB)serves as the last-line defense for the treatment of Gram-negative pathogens.Previous studies reported that BAC-adapted Pseudomonas aeruginosa increased the tolerance to PB.Herein,we present the novel finding that the combination of BAC and PB exhibited synergistic antibacterial effects against P.aeruginosa.Time-killing assay demonstrated a significant reduction in bacterial cell viability.Scanning electron microscopy,zeta potential analysis,hydrophobicity measurements,and fluorescence probe analyses collectively revealed severe disruption of the cell envelope and membrane potential induced by the combination of BAC and PB.Transcriptomic analysis revealed that the BAC-PB combination notably downreg-ulated the expression of genes involved in lipid A modification and cell envelope production,including phoPQ,pmrAB,bamABCDE,lptABCDEG,lolB,yidC,and murJ.Additionally,the combination group exhibited augmented production of reactive oxygen species and diminished ATP synthesis.The expression of the genes associated with substance metabolism and energy generation was significantly impeded.This study provides significant implica-tions for the interactions of biocides and antibiotics on Gram-negative pathogens,while also addressing antibiotic resistance and developing the external treatment strategy for Pseudomonas-infected wounds and burns. 展开更多
关键词 Pseudomonas aeruginosa Benzalkonium chloride Polymyxin B Synergistic effect Membrane disruption
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In situ self-assembly green synthesis of P-doped tubular carbon nitride for photocatalytic activation of PMS to rapidly degrade organic pollutants
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作者 Xiaomei Chen Deping Wang +1 位作者 Kejun Tan Lin Dong 《Journal of Environmental Sciences》 2026年第1期280-291,共12页
Peroxymonosulfate(PMS)-assisted visible-light photocatalytic degradation of organic pollutants using graphitic carbon nitride(g-C_(3)N_(4))presents a promising and environmentally friendly approach.However,pristine g-... Peroxymonosulfate(PMS)-assisted visible-light photocatalytic degradation of organic pollutants using graphitic carbon nitride(g-C_(3)N_(4))presents a promising and environmentally friendly approach.However,pristine g-C_(3)N_(4) suffers from limited visible-light absorption and low charge-carrier mobility.In this study,a phosphorus-doped tubular carbon nitride(5P-TCN)was synthesized via a precursor self-assembly method using phosphoric acid and melamine as raw materials,eliminating the need for organic solvents or templates.The 5P-TCN catalyst demonstrated enhanced visible-light absorption,improved charge transfer capability,and a 5.25-fold increase in specific surface area(31.092 m^(2)/g),which provided abundant active sites to efficiently drive the PMS-assisted photocatalytic reaction.The 5P-TCN/vis/PMS system exhibited exceptional degradation performance for organic pollutants across a broad pH range(3–9),achieving over 92%degradation of Rhodamine B(RhB)within 15 min.Notably,the system retained>98%RhB degradation efficiency after three consecutive operational cycles,demonstrating robust operational stability and reusability.Moreover,key parameters influencing,active radi-cals,degradation pathways,and potential mechanisms for RhB degradation were systematically investigated.This work proposes a green and cost-effective strategy for developing high-efficiency photocatalysts,while demon-strating the exceptional capability of a PMS-assisted photocatalytic system for rapid degradation of RhB. 展开更多
关键词 SELF-ASSEMBLY p-doped tubular carbon nitride Photocatalysis PMS activation Synergy effect
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Postoperative effective lens position and refraction changes with three different types of intraocular lens
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作者 Xi-Xia Ding Lin-Feng Xiang +5 位作者 Wen-Tao Tong Dan-Dan Wang Hong-FangZhang Ping-Jun Chang Fu-Man Yang Yun-E Zhao 《International Journal of Ophthalmology(English edition)》 2026年第2期260-265,共6页
AIM:To evaluate and compare alterations in the effective lens position(ELP)and refractive outcomes among three distinct intraocular lens(IOL)types.METHODS:Patients with cataracts were enrolled and allocated to 3 group... AIM:To evaluate and compare alterations in the effective lens position(ELP)and refractive outcomes among three distinct intraocular lens(IOL)types.METHODS:Patients with cataracts were enrolled and allocated to 3 groups:Group A(implanted with the SN6CWS),Group B(implanted with the MI60),and Group C(implanted with the Aspira-aA).ELP measurements were obtained with swept-source optical coherence tomography(SS-OCT)at 1d,1wk,1mo,and 3mo postoperatively.Subjective refraction assessments were conducted at 1wk,1mo,and 3mo following surgery.RESULTS:The study included 189 eyes of 150 cataract patients(66 males).There were 77 eyes in Group A,55 eyes in Group B,and 57 eyes in Group C.The root mean square of the ELP(ELPRMS)within the initial 3mo was significantly lower for Group A than for Groups B and C.Refractive changes within Group A were not significant across the time points of 1wk,1mo,and 3mo.Conversely,both Group B and Group C demonstrated statistically significant shifts toward hyperopia from 1wk to 3mo postsurgery.CONCLUSION:Among the three IOLs examined,the SN6CWS IOL showes the greatest stability during the first 3mo postoperatively.Between 1wk and 3mo after surgery,notable hyperopic shifts are evident in eyes implanted with the MI60 and Aspira-aA IOLs,whereas refractive outcomes remain relatively constant in eyes implanted with SN6CWS IOLs. 展开更多
关键词 effective lens position REFRACTION intraocular lens swept-source optical coherence tomography
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Effect of Thermoelectric Cooler Arrangements on Thermal Performance and Energy Saving in Electronic Applications:An Experimental Study
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作者 M.N.Abd-Al Ameer Iman S.Kareem Ali A.Ismaeel 《Energy Engineering》 2026年第1期511-526,共16页
Electrical and electronic devices face significant challenges in heatmanagement due to their compact size and high heat flux,which negatively impact performance and reliability.Conventional coolingmethods,such as forc... Electrical and electronic devices face significant challenges in heatmanagement due to their compact size and high heat flux,which negatively impact performance and reliability.Conventional coolingmethods,such as forced air cooling,often struggle to transfer heat efficiently.In contrast,thermoelectric coolers(TECs)provide an innovative active cooling solution to meet growing thermal management demands.In this research,a refrigerant based on mono ethylene glycol and distilled water was used instead of using gases,in addition to using thermoelectric cooling units instead of using a compressor in traditional refrigeration systems.This study evaluates the performance of a Peltierbased thermalmanagement systemby analyzing the effects of using two,three,and four Peltiermodules on cooling rates,power consumption,temperature reduction,and system efficiency.Experimental results indicate that increasing the number of Peltier modules significantly enhances cooling performance.The four-module system achieved an optimal balance between cooling speed and energy efficiency,reducing the temperature of a liquidmixture(30% mono ethylene glycol+70% distilled water plus laser dyes)to 8℃ in just 17 min.It demonstrated a cooling rate of 0.794℃/min and a high coefficient of performance(COP)of 1.2 while consuming less energy than the two-and three-module systems.Furthermore,the study revealed that increasing the number of modules led to faster air cooling and improved temperature reduction.These findings highlight the importance of selecting the optimal number of Peltier modules to enhance efficiency and cooling speed whileminimizing energy consumption.This makes TEC technology a sustainable and effective solution for applications requiring rapid and reliable thermal management. 展开更多
关键词 Energy consumption mono ethylene glycol Peltier effect performance factor(COP)
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Magnetic Properties and Kondo Effect in Ce_(3)TiBi_(5) under High Pressure
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作者 L.C.Fu W.J.Cheng +11 位作者 L.C.Shi B.S.Min Y.Peng J.Zhang J.Song Z.Deng J.F.Zhao Y.Liu J.L.Zhu J.F.Zhang X.C.Wang C.Q.Jin 《Chinese Physics Letters》 2026年第1期184-197,共14页
The magnetic properties and Kondo effect in Ce3TiBi5 with a quasi-one-dimensional structure were investigated using in situ high-pressure resistivity measurements up to 48 GPa.At ambient pressure,Ce_(3)TiBi_(5) underg... The magnetic properties and Kondo effect in Ce3TiBi5 with a quasi-one-dimensional structure were investigated using in situ high-pressure resistivity measurements up to 48 GPa.At ambient pressure,Ce_(3)TiBi_(5) undergoes an antiferromagnetic(AFM)transition at T_(N)∼5 K.Under high pressures within 8.9 GPa,we find that Kondo scattering contributes differently to the high-temperature resistance,R(T),depending on the applied current direction,demonstrating a significantly anisotropic Kondo effect.The complete P–T phase diagram has been constructed,in which the pressure dependence of T_(N) exhibits a dome-like shape.The AFM order remains robust under pressure,even when the coherence temperature T^(*) far exceeds 300 K.We attribute the observed anisotropic Kondo effect and the robust AFM to the underlying anisotropy in electronic hybridization under high pressure. 展开更多
关键词 magnetic properties resistivity measurements high pressure kondo effect kondo effectthe kondo scattering Ce TbI
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Investigation of natural and anthropogenic effects on aerosols optical properties over the Western Pacific ocean by the research vessel KEXUE
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作者 Jinyuan Xin Yining Ma +6 位作者 Xiangguang Zhang Yongjing Ma Xiaoyan Wu Fangkun Wu Quan Liu Yilong Lyu Jiawei Jiang 《Journal of Environmental Sciences》 2026年第1期596-605,共10页
In winter 2018,an aerosol physicochemical experiment was conducted in the Western Pacific Ocean(WPO)aboard the Research Vessel KEXUE of Chinese Academy of Sciences.This study systematically investigated both natural a... In winter 2018,an aerosol physicochemical experiment was conducted in the Western Pacific Ocean(WPO)aboard the Research Vessel KEXUE of Chinese Academy of Sciences.This study systematically investigated both natural and anthropogenic effects on marine aerosols optical properties,as well as the applicability of multi-satellite products and IMPROVE equation.The averaged aerosol optical depth(AOD500 nm)was 0.31±0.16 andÅngström exponent440–675 nm was 0.29±0.30.In offshore China,significant anthropogenic emissions affected the marine environment.In remote WPO,dust aerosols transported from northern China,Siberia,Central Asia,and those settling from the upper troposphere originating from north Africa,Arabian peninsula,and western India,were dominant.The spatial trends of AOD were opposite in the mid-latitude and southern seas of WPO.The highest AOD,0.32±0.23,appeared along the coast of South Asia at mid-latitude,decreasing from offshore seas to remote oceans.In low-latitude and equatorial seas,AOD significantly increased from coast to remote oceans.Ångström exponent dropped significantly from the coast to remote oceans as anthropogenic influence diminished across the entire WPO.Correlation analysis showed that both MODIS-C6 and Himawari AOD prod-ucts showed similar applicability in coastal urban areas,while Himawari AOD is highly recommended for coastal background and marine environment due to its finer resolution.The extinction coefficient derived from PM_(2.5) chemical compositions using IMPROVE algorithm exhibited a significant correlation(R^(2)=0.58)with the con-currently measured AOD in the absence of long-distance transport,suggesting that the IMPROVE is a reasonable proxy of the columnar average of marine aerosol extinctions free from transport influences. 展开更多
关键词 Aerosol optical properties Natural and anthropogenic effects Improve algorithm Ship-borne experiment Western Pacific Ocean
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Effectiveness and Safety of Lenvatinib and Everolimus after Immune Checkpoint Inhibitors in Metastatic Renal Cell Cancer:A Systematic Review
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作者 Giacomo Iovane Luca Traman +5 位作者 Michele Maffezzoli Giuseppe Fornarini Domenico Corradi Debora Guareschi Matteo Santoni Sebastiano Buti 《Oncology Research》 2026年第1期57-70,共14页
Background:While the treatment of metastatic renal cell carcinoma(mRCC)is evolving due to immune checkpoint inhibitors(ICIs),optimal strategies for later lines of therapy have yet to be defined.The combination of lenv... Background:While the treatment of metastatic renal cell carcinoma(mRCC)is evolving due to immune checkpoint inhibitors(ICIs),optimal strategies for later lines of therapy have yet to be defined.The combination of lenvatinib and everolimus represents a viable option,and the present review aimed to summarize its activity,effectiveness,and safety.Methods:A systematic review of the literature was conducted using PubMed,targeting studies published between 2018 and 2025.Eligible studies included English-language prospective and retrospective trials reporting survival outcomes in mRCC patients treated with lenvatinib and everolimus after at least one ICI-containing regimen.Results:Nine studies met the inclusion criteria,encompassing a total of 441 patients.The lenvatinib and everolimus combination was primarily used in the third and subsequent lines of therapy.Median overall survival ranged from 7.5 to 24.5 months,while median progression-free survival was more consistent,between 6.1 and 6.7 months,except for one study reporting 12.9 months.Objective response rates varied widely(14.0%–55.7%).Adverse events of grade≥3 did not exceed the expected rate,with diarrhoea and proteinuria as the most reported events.Dose reductions and treatment discontinuations due to toxicity occurred but were generally lower than in prior pivotal trials.Conclusions:Real-world evidence suggests that lenvatinib and everolimus represent an effective and safe option after ICI failure in mRCC patients.Nevertheless,the lack of randomized phase III trials and the heterogeneity of existing studies highlight the need for more robust prospective research to guide post-ICI therapeutic strategies. 展开更多
关键词 Metastatic renal cell carcinoma(mRCC) immune checkpoint inhibitors(ICIs) lenvatinib EVEROLIMUS effectIVENESS SAFETY systematic review
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血栓弹力图参数联合血清25(OH)D、P-选择素对妊娠期高血压疾病孕妇并发下肢深静脉血栓形成的预测价值
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作者 谭芳芳 金鑫 丁艳歌 《检验医学与临床》 2026年第1期106-111,共6页
目的探讨血栓弹力图(TEG)参数联合血清25-羟基维生素D[25(OH)D]、P-选择素对妊娠期高血压疾病(HDCP)孕妇并发下肢深静脉血栓形成(DVT)的预测价值。方法选取2021年6月至2023年6月该院收治的144例HDCP孕妇作为HDCP组,根据HDCP孕妇是否并... 目的探讨血栓弹力图(TEG)参数联合血清25-羟基维生素D[25(OH)D]、P-选择素对妊娠期高血压疾病(HDCP)孕妇并发下肢深静脉血栓形成(DVT)的预测价值。方法选取2021年6月至2023年6月该院收治的144例HDCP孕妇作为HDCP组,根据HDCP孕妇是否并发下肢DVT将所有孕妇分为下肢DVT组和非下肢DVT组。另选取同期在该院体检的144例健康孕妇作为对照组。采用多因素Logistic回归分析HDCP孕妇并发下肢DVT的影响因素。绘制受试者工作特征(ROC)曲线分析血清25(OH)D、P-选择素、凝血综合指数(CI)对HDCP孕妇并发下肢DVT的预测价值。结果HDCP组血清25(OH)D水平低于对照组,P-选择素水平高于对照组,差异均有统计学意义(P<0.05)。下肢DVT组41例,非下肢DVT组103例。下肢DVT组血清25(OH)D水平、凝血反应时间(R)、血块动力值(K)均低于非下肢DVT组,P-选择素水平、α角、最大血块强度(MA)、CI均高于非下肢DVT组,差异均有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,25(OH)D水平升高是HDCP孕妇并发下肢DVT的保护因素,CI、HDCP分期(子痫及子痫前期)及P-选择素水平升高均是HDCP孕妇并发下肢DVT的危险因素(P<0.05)。ROC曲线分析结果显示,血清25(OH)D、P-选择素及CI联合预测HDC P孕妇并发下肢DVT的曲线下面积(AUC)为0.939,大于3项单独预测的AUC(0.850、0.807、0.791),差异均有统计学意义(Z=2.141、3.248、3.589,P<0.05)。结论HDCP孕妇血清25(OH)D水平降低、P-选择素水平升高,且均与并发下肢DVT有关,血清25(OH)D、P-选择素及CI联合检测对HDCP孕妇并发下肢DVT的预测价值较高。 展开更多
关键词 妊娠期高血压疾病 下肢 深静脉血栓形成 血栓弹力图 25-羟基维生素D p-选择素 预测价值
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Lithium Nitrate Effects for Lithium-Based Chemical Batteries:A Review
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作者 Xianshu Wang Junru Wu +6 位作者 Huirong Wang Xiangshao Yin Zhuo Zhou Yuanyuan Huang Yelong Zhang Weishan Li Baohua Li 《Carbon Energy》 2026年第1期197-222,共26页
Lithium metal batteries(LMBs)have been regarded as one of the most promising alternatives in the post-lithium battery era due to their high energy density,which meets the needs of light-weight electronic devices and l... Lithium metal batteries(LMBs)have been regarded as one of the most promising alternatives in the post-lithium battery era due to their high energy density,which meets the needs of light-weight electronic devices and long-range electric vehicles.However,technical barriers such as dendrite growth and poor Li plating/stripping reversibility severely hinder the practical application of LMBs.However,lithium nitrate(LiNO_(3))is found to be able to stabilize the Li/electrolyte interface and has been used to address the above challenges.To date,considerable research efforts have been devoted toward understanding the roles of LiNO_(3) in regulating the surface properties of Li anodes and toward the development of many effective strategies.These research efforts are partially mentioned in some articles on LMBs and yet have not been reviewed systematically.To fill this gap,we discuss the recent advances in fundamental and technological research on LiNO_(3) and its derivatives for improving the performances of LMBs,particularly for Li-sulfur(S),Li-oxygen(O),and Li-Li-containing transition-metal oxide(LTMO)batteries,as well as LiNO_(3)-containing recipes for precursors in battery materials and interphase fabrication.This review pays attention to the effects of LiNO_(3) in lithium-based batteries,aiming to provide scientific guidance for the optimization of electrode/electrolyte interfaces and enrich the design of advanced LMBs. 展开更多
关键词 effects and mechanisms LiNO_(3)derivatives LiNO_(3)-containing recipes lithium metal anode Lithium nitrate basis lithium-based chemical batteries
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Effect of stress on microstructures of creep-aged 2524 alloy 被引量:3
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作者 权力伟 赵刚 +1 位作者 田妮 黄明丽 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2013年第8期2209-2214,共6页
Microstructures of creep-aged 2524 (A1-4.3Cu-1.5Mg) aged at 170 ℃ with various stresses (0, 173 and 250 MPa) were studied on a creep machine. Ageing hardness curves under various stresses were plotted and the cor... Microstructures of creep-aged 2524 (A1-4.3Cu-1.5Mg) aged at 170 ℃ with various stresses (0, 173 and 250 MPa) were studied on a creep machine. Ageing hardness curves under various stresses were plotted and the corresponding microstructures were characterized by transmission electron microscopy (TEM). The results show that the value of peak hardness is increased, while the time to reach the peak hardness is reduced under an external stress. Meanwhile, the length of S(Al2CuMg) phase is shorter and the number density of S phases is larger in the creep-aged alloy. The predominant contribution to the peak hardness can be ascribed to the GPB zones with an elastic stress. 展开更多
关键词 creep-age S phase GPB zone hardness DISLOCATION stress orientation effect
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Effect of wear conditions on tribological properties of electrolessly-deposited Ni-P-Gr-SiC hybrid composite coating 被引量:2
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作者 何美凤 胡文彬 +3 位作者 钟澄 翁俊飞 沈彬 仵亚婷 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2012年第10期2586-2592,共7页
The friction and wear properties of the electrolessly-deposited Ni-P-Gr-SiC composites were investigated. The effects of graphite content, load and rotation speed on the friction coefficient and wear resistance of the... The friction and wear properties of the electrolessly-deposited Ni-P-Gr-SiC composites were investigated. The effects of graphite content, load and rotation speed on the friction coefficient and wear resistance of the composite coatings were mainly investigated. The worn surface and cross section of the coatings were characterized by scanning electron microscopy and energy-dispersive X-ray analysis. The results show that the composite coatings reveal good antifriction and wear resistance due to the synergic effect of graphite and SiC particles. The formation of graphite-rich mechanically mixed layer (GRMML) on the surface of Ni-P-Gr-SiC coating contributes to the good tribological behavior of the wear counterparts and SiC particles play a load bearing role in protecting GRMML from shearing easily. 展开更多
关键词 electroless composite coating Ni-P coating GRAPHITE SIC tribological property SELF-LUBRICATION synergic effect
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基于AHP-模糊综合评价法的演出领域标准实施效果评价研究
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作者 胡晓群 刘建华 《中国标准化》 2026年第1期77-85,94,共10页
对标准的实施效果进行评价是开展标准化工作的重要环节,构建评价指标体系是评价的基础和关键点。本文以演出领域的一项推荐性国家标准作为案例,综合运用层次分析法和模糊综合评价法,从标准技术内容、实施情况、实施效益3个方面构建标准... 对标准的实施效果进行评价是开展标准化工作的重要环节,构建评价指标体系是评价的基础和关键点。本文以演出领域的一项推荐性国家标准作为案例,综合运用层次分析法和模糊综合评价法,从标准技术内容、实施情况、实施效益3个方面构建标准实施效果评价指标体系,提出一套可适用于演出领域标准实施效果评价方法。通过案例分析,验证评价方法的实际应用效果,针对不同标准的实施效果评价,可参考本文所述的评价方法,并结合具体评价对象的实际情况,开展评价工作。 展开更多
关键词 演出领域标准 实施效果 评价方法
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GeSi Source/Drain Structure for Suppression of Short Channel Effect in SOI p-MOSFET's
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作者 黄如 卜伟海 王阳元 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2001年第2期121-125,共5页
GeSi source/drain structure is purposefully adopted in SOI p MOSFET's to suppress the short channel effect (SCE).The impact of GeSi material (as source only,drain only or both source and drain) on the threshold v... GeSi source/drain structure is purposefully adopted in SOI p MOSFET's to suppress the short channel effect (SCE).The impact of GeSi material (as source only,drain only or both source and drain) on the threshold voltage rolling off and DIBL effect is thoroughly investigated,as well as the influence of the Ge concentration and silicon film thickness.The Ge concentration should be carefully chosen as a tradeoff between the driving current and SCE improvement.The detailed physics is explained. 展开更多
关键词 short channel effect MOSFET SOI
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