The sense of mammalian hearing exhibits nonlinear phenomena which are most significant to hearing function, such as nonlinear dynamic compression, nonlinear tuning and combination tones. These nonlinear phenomena are ...The sense of mammalian hearing exhibits nonlinear phenomena which are most significant to hearing function, such as nonlinear dynamic compression, nonlinear tuning and combination tones. These nonlinear phenomena are suggested to originate from the Hopf amplification within the cochlea, while the mechanism underlying the Hopf amplification remains elusive. According to the experimental results of force-gating channel operation in hair cells, through a theoretic model, this work reveals a velocity-dependent open probability of force-gating channels in auditory hair cells, and a velocity-dependent active force produced by the force-gating channel operating, which makes sensors hear typical Hopf vibrators with nonlinear hearing phenomena.展开更多
To elucidate the feasibility of retroviral mediatedtransfer of multidrug resistance gene (mdrl) intohematopoietic stem/progenitor cells, the CD34^+ cellswere isolated from bone marrow by using a high-gradient.magnetic...To elucidate the feasibility of retroviral mediatedtransfer of multidrug resistance gene (mdrl) intohematopoietic stem/progenitor cells, the CD34^+ cellswere isolated from bone marrow by using a high-gradient.magnetic cell sorting system, and the efficiency ofretroviral mediated gene transfer was studied.展开更多
Bikutsi is an ethnic dance practiced by the Bed people who live mainly in Cameroon's Central Region.In Ewondo,the local language spoken in Yaounde,the capital of Cameroon,the rhythm is pronounced MBiakut si,"...Bikutsi is an ethnic dance practiced by the Bed people who live mainly in Cameroon's Central Region.In Ewondo,the local language spoken in Yaounde,the capital of Cameroon,the rhythm is pronounced MBiakut si,"meaning Hwe hit the ground,"usually danced by making undulations of the upper and lower limbs of the body to a tempo amplified by synchronized instruments,resulting in a frenetic and very lively rhythm.展开更多
This paper refutes the mechanistic interpretation of cellular dynamics and contends that the life-giving principle is sustained growth a biological system and is uninterrupted growth balanced in a dynamic state by syn...This paper refutes the mechanistic interpretation of cellular dynamics and contends that the life-giving principle is sustained growth a biological system and is uninterrupted growth balanced in a dynamic state by synthesis and dissolution. The process began by an oxidation/reduction reaction on the surface of pyrite energized photovoltaically by sunlight. Hydrogen sulfide was oxidized, carbon dioxide was reduced, and phosphate on the surface of the pyrite was a reactant. The first organic compounds were sulfides and phosphoglycerates. These organophosphates were at the center of the energy cycle of all life where the dehydration of a relatively unreactive ＂low-energy＂ two-phosphoglycerate transforms it into the ＂high-energy＂ phosphoenolpyruvate. Life began as a growth process and continues to grow ceaselessly out of necessity. It cannot discontinue the life-giving energy flow without irreparable loss of the process. All forms of life past and present were and are stabilized systems in which the growth process is contained in metabolic turnover.展开更多
To the Editor:Since 1027,when the Tian Sheng Bronze Statue showing acupoints and meridians was first introduced for medical practitioners,it has evolved to the currently used acupoints and meridians atlas in tradition...To the Editor:Since 1027,when the Tian Sheng Bronze Statue showing acupoints and meridians was first introduced for medical practitioners,it has evolved to the currently used acupoints and meridians atlas in traditional Chinese medicine(TCM).[1]To date,the acupoints represent defined areas on the body surface relative to certain landmarks.The acupoints in the extremity endings would connect anatomically with diverse associated visceral organs or tissues,forming a Meridian and Collateral network.Illustrated on the atlas,each main meridian is usually a virtual line connecting a group of adjacent acupoints that correlate with certain visceral organ.In modern medical science,the anatomical structures of main meridians remain largely unclarified.展开更多
Food Science of Animal Products(ISSN:2958-4124,e-ISSN:2958-3780)is a peer-reviewed,open access international journal that publishes the latest research findings in the field of animal-origin foods,involving food mater...Food Science of Animal Products(ISSN:2958-4124,e-ISSN:2958-3780)is a peer-reviewed,open access international journal that publishes the latest research findings in the field of animal-origin foods,involving food materials such as meat,aquatic products,milk,eggs,animal offals and edible insects.展开更多
Modern Landscape Design Originated in China1Author:Yu Changbin Year:2013Publisher:China Machine Press ISBN:9787111314318,711131431X(367pages,in Chinese)Under China’s surging economy,the life quality of Chinese people...Modern Landscape Design Originated in China1Author:Yu Changbin Year:2013Publisher:China Machine Press ISBN:9787111314318,711131431X(367pages,in Chinese)Under China’s surging economy,the life quality of Chinese people has changed deeply,having realized the historical leap from simply having enough food and clothing to leading a relatively comfortable life.As people put forward higher living standards,展开更多
Strong rainfall events originated from the northeast(NE)and southwest(SW)directions of the plain area of Beijing City(BJP)over 8 recent warm seasons(May–September of 2009–2016)were analyzed by using hourly merged ra...Strong rainfall events originated from the northeast(NE)and southwest(SW)directions of the plain area of Beijing City(BJP)over 8 recent warm seasons(May–September of 2009–2016)were analyzed by using hourly merged rainfall,satellite brightness temperature,and the fifth-generation ECMWF reanalysis(ERA5)data.Such heavy regional rainfall events(RREs)with different origins present quite different features in both the precipitation itself and its corresponding circulations.The heavy RREs originated from the SW occur more frequently in the flood season of North China(July and August),and the peak time of rainfall occurrences is in the early morning.They are linked with stronger large-scale circulation forcing,compared with the NE-originated events.Meanwhile,the ratio of heavy rainfall to the total rainfall in SW-originated events,the mean spatial coverage of rainfall,and associated convective index,are also larger,for the SW events.The heavy RREs from the NE occur more frequently in June and July(before the traditional flood season),with a more apparent afternoon peak.They exhibit stronger convective features,with higher maximum convective index values,but the large-scale forcing is weaker at the hour of onset.These features of the RREs from different directions of Beijing City and associated precursor circulation signals help better forecast RREs over the BJP.展开更多
China’s Einstein Probe(EP)astronomical satellite has,for the first time in human history,detected soft X-ray signals from an explosion in the early universe,opening a new window for research into the young cosmos.The...China’s Einstein Probe(EP)astronomical satellite has,for the first time in human history,detected soft X-ray signals from an explosion in the early universe,opening a new window for research into the young cosmos.The findings were published in the journal Nature Astronomy on January 23,2025.The Wide-field X-ray Telescope onboard the EP satellite observed a faint pulse signal from a burst event in the soft X-ray band on March 15,2024.This burst,designated as EP240315a,exhibited rapid brightness fluctuations and persisted for over 17 minutes before gradually fading away.Subsequent observations by telescopes from other countries confirmed that this burst originated from the distant early universe.展开更多
If the singularity of the cosmic Big Bang is taken as the origin of the reference coordinate system,the surrounding vacuum in the initial moments of it would exhibit radially-outward right-handed spiral motion at ligh...If the singularity of the cosmic Big Bang is taken as the origin of the reference coordinate system,the surrounding vacuum in the initial moments of it would exhibit radially-outward right-handed spiral motion at light speed.Based on this spatial motion hypothesis,we derive a unified field equation and a set of Maxwell’s equations for vacuum SWs(Scalar Waves)generating a huge spiral force field that drives the energy to spiral inwardly and distort,leading to the formation of mass.Furthermore,they also uncover that mass is fundamentally an ultimate expression of energy,manifesting as the result of spiral motion of space at light speed.And then,we indirectly validate the theory that coherent light waves’collision generate SWs and subsequently mass through the experiment verifying the Breit-Wheeler process.The establishment of our theory offers a new analytical tool for the exploration of mass origin,the cosmic Big Bang,unified field theories.展开更多
China's Northern and Southern Dynasties period(3rd–6th centuries AD)marked a significant era of ethnic integration in northern China.However,previous ancient DNA studies have primarily focused on northern ethnic ...China's Northern and Southern Dynasties period(3rd–6th centuries AD)marked a significant era of ethnic integration in northern China.However,previous ancient DNA studies have primarily focused on northern ethnic groups,with limited research on the genetic formation of the hereditary elite family,especially considering their abundant archaeological record and clear material identity.In this study,we obtain the ancient genome of a hereditary elite family,Gao Bin(高宾,503 AD–572 AD),at 0.6473-fold coverage with 475,132 single-nucleotide polymorphisms(SNPs)on the 1240k panel.His mitochondrial haplogroup belongs to Z4 and Y-haplogroup to O1a1a2b-F2444∗.The genetic profile of Gao Bin is most similar to that of the northern Han Chinese.He can be modeled as deriving all his ancestry from Late Neolithic to Iron Age Yellow River farmers without influence from Northeast Asia,Korea,or the Mongolian Plateau.Our study sheds light on the genetic formation of hereditary elite families in the context of the Southern and Northern Dynasties ethnic integration.展开更多
Hydrocarbons are one of the important fluids within the Earth's crust,and different biotic and abitoic processes can generate hydrocarbon during geological periods.Tracing the sources and sinks of hydrocarbons can...Hydrocarbons are one of the important fluids within the Earth's crust,and different biotic and abitoic processes can generate hydrocarbon during geological periods.Tracing the sources and sinks of hydrocarbons can help us better understand the carbon cycle of the earth.In this study,an improved approach of adsorbed hydrocarbons extraction from sediments was established.The improved thermal desorption approach,compound-specific isotope analysis and position-specific isotope analysis were integrated to investigate the molecular and intramolecular isotope fractionation between trace hydrocarbon gases within sediments and geological hydrocarbon deposits.The isotopic compositions of the terminal position carbon of propane(δ^(13)C_(terminal))serves as a correlation indicator between trace hydrocarbon gases within sediments and geological hydrocarbon deposits.The tight sandstone gas from the Turpan-Hami Basin is a first case study for the application of this novel method to trace hydrocarbon origins.The results showed that the hydrocarbons in the tight sandstone gases in the study area most likely originated from humic organic matter(typeⅢkerogen)at an early mature stage.δ^(13)C_(terminal)values of the thermally desorbed propane gases from different source rocks were distinguishable and the values of the tight sandstone gases significantly overlap with those of the Lower Jurassic Sangonghe source rocks,suggesting their genetic relationship.Overall,the results provided novel position-specific carbon isotopic constraints on origins of hydrocarbons.展开更多
Xi Jinping,general secretary of the Communist Party of China(CPC)Central Committee,stressed that we should adhere to the“two integrations”(namely,integrating the basic tenets of Marxism with China’s specific realit...Xi Jinping,general secretary of the Communist Party of China(CPC)Central Committee,stressed that we should adhere to the“two integrations”(namely,integrating the basic tenets of Marxism with China’s specific realities and fine traditional culture),root ourselves in Chinese soil,carry forward the Chinese cultural heritage,and strengthen the academic foundation.We should accelerate the building of an independent knowledge system for Chinese philosophy and social sciences,and formulate original concepts and develop systems of academic discipline,research and discourse,drawing on China’s rich experience of advancing human rights.In the face of changes of a magnitude not seen in a century,in the historic process of advancing the great rejuvenation of the Chinese nation on all fronts through Chinese modernization,we should and must strengthen our theoretical self-consciousness and confidence in the path of Chinese modernization.We need to enhance human rights research,develop the human rights theoretical system and paradigm that are based on Chinese realities and express Chinese voice,and an independent Chinese knowledge system for human rights.展开更多
Aim Journal of Shenzhen University Science and Engineering,a bimonthly journal with its first issuing in 1984,is now administered and sponsored by Shenzhen University and published by the Science Press.It is a peer-re...Aim Journal of Shenzhen University Science and Engineering,a bimonthly journal with its first issuing in 1984,is now administered and sponsored by Shenzhen University and published by the Science Press.It is a peer-reviewed journal that publishes original papers of high scientific value.Innovation is always the starting point for the progress of our journal.We pay more attention to funded projects and major topics during manuscript organization to present the latest scientific and engineering achievements in China,as well as innovations in Shenzhen and Shenzhen University.展开更多
基金Supported by the National Natural Science Foundation of China under Grant No 11374118the Science Foundation of Hubei Province under Grant No 2013CFB289
文摘The sense of mammalian hearing exhibits nonlinear phenomena which are most significant to hearing function, such as nonlinear dynamic compression, nonlinear tuning and combination tones. These nonlinear phenomena are suggested to originate from the Hopf amplification within the cochlea, while the mechanism underlying the Hopf amplification remains elusive. According to the experimental results of force-gating channel operation in hair cells, through a theoretic model, this work reveals a velocity-dependent open probability of force-gating channels in auditory hair cells, and a velocity-dependent active force produced by the force-gating channel operating, which makes sensors hear typical Hopf vibrators with nonlinear hearing phenomena.
文摘To elucidate the feasibility of retroviral mediatedtransfer of multidrug resistance gene (mdrl) intohematopoietic stem/progenitor cells, the CD34^+ cellswere isolated from bone marrow by using a high-gradient.magnetic cell sorting system, and the efficiency ofretroviral mediated gene transfer was studied.
文摘Bikutsi is an ethnic dance practiced by the Bed people who live mainly in Cameroon's Central Region.In Ewondo,the local language spoken in Yaounde,the capital of Cameroon,the rhythm is pronounced MBiakut si,"meaning Hwe hit the ground,"usually danced by making undulations of the upper and lower limbs of the body to a tempo amplified by synchronized instruments,resulting in a frenetic and very lively rhythm.
文摘This paper refutes the mechanistic interpretation of cellular dynamics and contends that the life-giving principle is sustained growth a biological system and is uninterrupted growth balanced in a dynamic state by synthesis and dissolution. The process began by an oxidation/reduction reaction on the surface of pyrite energized photovoltaically by sunlight. Hydrogen sulfide was oxidized, carbon dioxide was reduced, and phosphate on the surface of the pyrite was a reactant. The first organic compounds were sulfides and phosphoglycerates. These organophosphates were at the center of the energy cycle of all life where the dehydration of a relatively unreactive ＂low-energy＂ two-phosphoglycerate transforms it into the ＂high-energy＂ phosphoenolpyruvate. Life began as a growth process and continues to grow ceaselessly out of necessity. It cannot discontinue the life-giving energy flow without irreparable loss of the process. All forms of life past and present were and are stabilized systems in which the growth process is contained in metabolic turnover.
基金supported by grants from the Beijing Hospital Clinical Research 121 Project(No.121-2016002)the National Natural Science Foundation of China(Nos.82050004,82050005,12050001)the CAMS Innovation Fund for Medical Sciences(CIFMS No.2017-I2M-3-008).
文摘To the Editor:Since 1027,when the Tian Sheng Bronze Statue showing acupoints and meridians was first introduced for medical practitioners,it has evolved to the currently used acupoints and meridians atlas in traditional Chinese medicine(TCM).[1]To date,the acupoints represent defined areas on the body surface relative to certain landmarks.The acupoints in the extremity endings would connect anatomically with diverse associated visceral organs or tissues,forming a Meridian and Collateral network.Illustrated on the atlas,each main meridian is usually a virtual line connecting a group of adjacent acupoints that correlate with certain visceral organ.In modern medical science,the anatomical structures of main meridians remain largely unclarified.
文摘Food Science of Animal Products(ISSN:2958-4124,e-ISSN:2958-3780)is a peer-reviewed,open access international journal that publishes the latest research findings in the field of animal-origin foods,involving food materials such as meat,aquatic products,milk,eggs,animal offals and edible insects.
文摘Modern Landscape Design Originated in China1Author:Yu Changbin Year:2013Publisher:China Machine Press ISBN:9787111314318,711131431X(367pages,in Chinese)Under China’s surging economy,the life quality of Chinese people has changed deeply,having realized the historical leap from simply having enough food and clothing to leading a relatively comfortable life.As people put forward higher living standards,
基金Supported by the National Key Research and Development Program of China(2018YFE0196000 and 2018YFC1507603)National Natural Science Foundation of China(41675075 and 41875112)。
文摘Strong rainfall events originated from the northeast(NE)and southwest(SW)directions of the plain area of Beijing City(BJP)over 8 recent warm seasons(May–September of 2009–2016)were analyzed by using hourly merged rainfall,satellite brightness temperature,and the fifth-generation ECMWF reanalysis(ERA5)data.Such heavy regional rainfall events(RREs)with different origins present quite different features in both the precipitation itself and its corresponding circulations.The heavy RREs originated from the SW occur more frequently in the flood season of North China(July and August),and the peak time of rainfall occurrences is in the early morning.They are linked with stronger large-scale circulation forcing,compared with the NE-originated events.Meanwhile,the ratio of heavy rainfall to the total rainfall in SW-originated events,the mean spatial coverage of rainfall,and associated convective index,are also larger,for the SW events.The heavy RREs from the NE occur more frequently in June and July(before the traditional flood season),with a more apparent afternoon peak.They exhibit stronger convective features,with higher maximum convective index values,but the large-scale forcing is weaker at the hour of onset.These features of the RREs from different directions of Beijing City and associated precursor circulation signals help better forecast RREs over the BJP.
文摘China’s Einstein Probe(EP)astronomical satellite has,for the first time in human history,detected soft X-ray signals from an explosion in the early universe,opening a new window for research into the young cosmos.The findings were published in the journal Nature Astronomy on January 23,2025.The Wide-field X-ray Telescope onboard the EP satellite observed a faint pulse signal from a burst event in the soft X-ray band on March 15,2024.This burst,designated as EP240315a,exhibited rapid brightness fluctuations and persisted for over 17 minutes before gradually fading away.Subsequent observations by telescopes from other countries confirmed that this burst originated from the distant early universe.
文摘If the singularity of the cosmic Big Bang is taken as the origin of the reference coordinate system,the surrounding vacuum in the initial moments of it would exhibit radially-outward right-handed spiral motion at light speed.Based on this spatial motion hypothesis,we derive a unified field equation and a set of Maxwell’s equations for vacuum SWs(Scalar Waves)generating a huge spiral force field that drives the energy to spiral inwardly and distort,leading to the formation of mass.Furthermore,they also uncover that mass is fundamentally an ultimate expression of energy,manifesting as the result of spiral motion of space at light speed.And then,we indirectly validate the theory that coherent light waves’collision generate SWs and subsequently mass through the experiment verifying the Breit-Wheeler process.The establishment of our theory offers a new analytical tool for the exploration of mass origin,the cosmic Big Bang,unified field theories.
基金funded by the National Natural Science Foundation of China(32070576,31801040,and 32270667)Lantai Young Scholars Program of Chinese History Institute(2022LTQN602)+11 种基金the National Social Science Fund of China(19VJX074 and 21CKG022)Priority Research Program of the Chinese Academy of Sciences:Pan-Third Pole Environment Study for a Green Silk Road(Pan-TPE)(XDA2004010101)the National Key Research and Development Program(2023YFC3303701-02)the Natural Science Foundation of Fujian Province of China(2023J06013)the Science and Technology Commission of Shanghai Municipality(18490750300)the National Key Research and Development Program(2020YFE0201600)Shanghai Municipal Science and Technology Major Project(2017SHZDZX01)the Major Project of National Social Science Foundation of China granted to C.C.W.(21&ZD285),S.W.(20&ZD212),and D.L.(21&ZD237)Major Special Project of Philosophy and Social Sciences Research of the Ministry of Education(2022JZDZ023)Open Research Fund of State Key Laboratory of Genetic Engineering at Fudan University(SKLGE-2310)Open Research Fund of Forensic Genetics Key Laboratory of the Ministry of Public Security(2023FGKFKT07)European Research Council(ERC)grant(ERC-2019-ADG-883700-TRAM).
文摘China's Northern and Southern Dynasties period(3rd–6th centuries AD)marked a significant era of ethnic integration in northern China.However,previous ancient DNA studies have primarily focused on northern ethnic groups,with limited research on the genetic formation of the hereditary elite family,especially considering their abundant archaeological record and clear material identity.In this study,we obtain the ancient genome of a hereditary elite family,Gao Bin(高宾,503 AD–572 AD),at 0.6473-fold coverage with 475,132 single-nucleotide polymorphisms(SNPs)on the 1240k panel.His mitochondrial haplogroup belongs to Z4 and Y-haplogroup to O1a1a2b-F2444∗.The genetic profile of Gao Bin is most similar to that of the northern Han Chinese.He can be modeled as deriving all his ancestry from Late Neolithic to Iron Age Yellow River farmers without influence from Northeast Asia,Korea,or the Mongolian Plateau.Our study sheds light on the genetic formation of hereditary elite families in the context of the Southern and Northern Dynasties ethnic integration.
基金financially supported by the National Natural Science Foundation of China(Grant No.42102202)U.S.Department of Energy Geosciences program(DE-SC0016271)。
文摘Hydrocarbons are one of the important fluids within the Earth's crust,and different biotic and abitoic processes can generate hydrocarbon during geological periods.Tracing the sources and sinks of hydrocarbons can help us better understand the carbon cycle of the earth.In this study,an improved approach of adsorbed hydrocarbons extraction from sediments was established.The improved thermal desorption approach,compound-specific isotope analysis and position-specific isotope analysis were integrated to investigate the molecular and intramolecular isotope fractionation between trace hydrocarbon gases within sediments and geological hydrocarbon deposits.The isotopic compositions of the terminal position carbon of propane(δ^(13)C_(terminal))serves as a correlation indicator between trace hydrocarbon gases within sediments and geological hydrocarbon deposits.The tight sandstone gas from the Turpan-Hami Basin is a first case study for the application of this novel method to trace hydrocarbon origins.The results showed that the hydrocarbons in the tight sandstone gases in the study area most likely originated from humic organic matter(typeⅢkerogen)at an early mature stage.δ^(13)C_(terminal)values of the thermally desorbed propane gases from different source rocks were distinguishable and the values of the tight sandstone gases significantly overlap with those of the Lower Jurassic Sangonghe source rocks,suggesting their genetic relationship.Overall,the results provided novel position-specific carbon isotopic constraints on origins of hydrocarbons.
文摘Xi Jinping,general secretary of the Communist Party of China(CPC)Central Committee,stressed that we should adhere to the“two integrations”(namely,integrating the basic tenets of Marxism with China’s specific realities and fine traditional culture),root ourselves in Chinese soil,carry forward the Chinese cultural heritage,and strengthen the academic foundation.We should accelerate the building of an independent knowledge system for Chinese philosophy and social sciences,and formulate original concepts and develop systems of academic discipline,research and discourse,drawing on China’s rich experience of advancing human rights.In the face of changes of a magnitude not seen in a century,in the historic process of advancing the great rejuvenation of the Chinese nation on all fronts through Chinese modernization,we should and must strengthen our theoretical self-consciousness and confidence in the path of Chinese modernization.We need to enhance human rights research,develop the human rights theoretical system and paradigm that are based on Chinese realities and express Chinese voice,and an independent Chinese knowledge system for human rights.
文摘Aim Journal of Shenzhen University Science and Engineering,a bimonthly journal with its first issuing in 1984,is now administered and sponsored by Shenzhen University and published by the Science Press.It is a peer-reviewed journal that publishes original papers of high scientific value.Innovation is always the starting point for the progress of our journal.We pay more attention to funded projects and major topics during manuscript organization to present the latest scientific and engineering achievements in China,as well as innovations in Shenzhen and Shenzhen University.
