AIM:To determine the incidence of surgical injury during deceased donor organ procurements.METHODS:Organ damage was classified into three tiers,from 1-3,with the latter rendering the organ nontransplantable.For 12 con...AIM:To determine the incidence of surgical injury during deceased donor organ procurements.METHODS:Organ damage was classified into three tiers,from 1-3,with the latter rendering the organ nontransplantable.For 12 consecutive months starting in January of 2014,36 of 58 organ procurement organization's(OPO)'s prospectively submitted quality data regarding organ damage(as reported by the transplanting surgeon and confirmed by the OPO medical director)seen on the procured organ.RESULTS:These 36 OPOs recovered 5401 of the nations's 8504 deceased donors for calendar year 2014.A total of 19043 organs procured were prospectively analyzed.Of this total,59 organs sustained damage making them non-transplantable(0 intestines;4 pancreata;5 lungs;6 livers;43 kidneys).The class 3 damage was spread over 22(of 36)reporting OPO's.CONCLUSION:While damage to the procured organ is rare with organ loss being approximately 0.3%of procured organs,loss of potential transplantable organs does occur during procurement.展开更多
BACKGROUND： In 2011, a pilot program for deceased organ donation was initiated in China. We describe the first successful series of liver transplants in the pilot program.METHODS： From July 2011 to August 2012, our ...BACKGROUND： In 2011, a pilot program for deceased organ donation was initiated in China. We describe the first successful series of liver transplants in the pilot program.METHODS： From July 2011 to August 2012, our center performed 26 liver transplants from a pool of 29 deceased donors. All organ donation and allograft procurement were conducted according to the national protocol. The clinical data of donors and recipients were collected and summarized retrospectively.RESULTS： Among the 29 donors, 24 were China Category II donors（organ donation after cardiac death）, and five were China Category III donors（organ donation after brain death followed by cardiac death）. The recipients were mainly the patients with hepatocellular carcinoma. The one-year patient survival rate was 80.8% with a median follow-up of 422（2-696） days. Among the five mortalities during the follow-up,three died of tumor recurrence. In terms of post-transplant complications, 9 recipients（34.6%） experienced early allograft dysfunction, 1（3.8%） had non-anastomotic biliary stricture,and 1（3.8%） was complicated with hepatic arterial thrombosis.None of these complications resulted in patient death. Notably,primary non-function was not observed in any of the grafts.CONCLUSION： With careful donor selection, liver transplant from deceased donors can be performed safely and plays acritical role in overcoming the extreme organ shortage in China.展开更多
文摘AIM:To determine the incidence of surgical injury during deceased donor organ procurements.METHODS:Organ damage was classified into three tiers,from 1-3,with the latter rendering the organ nontransplantable.For 12 consecutive months starting in January of 2014,36 of 58 organ procurement organization's(OPO)'s prospectively submitted quality data regarding organ damage(as reported by the transplanting surgeon and confirmed by the OPO medical director)seen on the procured organ.RESULTS:These 36 OPOs recovered 5401 of the nations's 8504 deceased donors for calendar year 2014.A total of 19043 organs procured were prospectively analyzed.Of this total,59 organs sustained damage making them non-transplantable(0 intestines;4 pancreata;5 lungs;6 livers;43 kidneys).The class 3 damage was spread over 22(of 36)reporting OPO's.CONCLUSION:While damage to the procured organ is rare with organ loss being approximately 0.3%of procured organs,loss of potential transplantable organs does occur during procurement.
基金supported by grants from the National High Technology Research and Development Program of China(863 Program)(2012AA021008)the Special Fund for Science Research by Ministry of Health(201302009)
文摘BACKGROUND： In 2011, a pilot program for deceased organ donation was initiated in China. We describe the first successful series of liver transplants in the pilot program.METHODS： From July 2011 to August 2012, our center performed 26 liver transplants from a pool of 29 deceased donors. All organ donation and allograft procurement were conducted according to the national protocol. The clinical data of donors and recipients were collected and summarized retrospectively.RESULTS： Among the 29 donors, 24 were China Category II donors（organ donation after cardiac death）, and five were China Category III donors（organ donation after brain death followed by cardiac death）. The recipients were mainly the patients with hepatocellular carcinoma. The one-year patient survival rate was 80.8% with a median follow-up of 422（2-696） days. Among the five mortalities during the follow-up,three died of tumor recurrence. In terms of post-transplant complications, 9 recipients（34.6%） experienced early allograft dysfunction, 1（3.8%） had non-anastomotic biliary stricture,and 1（3.8%） was complicated with hepatic arterial thrombosis.None of these complications resulted in patient death. Notably,primary non-function was not observed in any of the grafts.CONCLUSION： With careful donor selection, liver transplant from deceased donors can be performed safely and plays acritical role in overcoming the extreme organ shortage in China.
