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Common Issues Identified in the Registration Labels of Ordinary Cosmetics in Beijing and Regulatory Countermeasures
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作者 Sun Lu 《China Detergent & Cosmetics》 2025年第2期16-24,共9页
This study summarizes the examination data of registration labels for ordinary cosmetics in Beijing from May 2021 to April 2024.It analyzes and categorizes the issues identified during label evaluations,explores the u... This study summarizes the examination data of registration labels for ordinary cosmetics in Beijing from May 2021 to April 2024.It analyzes and categorizes the issues identified during label evaluations,explores the underlying causes,and proposes regulatory countermeasures and recommendations for registrants,regulatory authorities,and social organizations.The objective is to offer practical insights and regulatory guidance to support the enhancement of cosmetic registration and regulatory standards. 展开更多
关键词 ordinary cosmetics REGISTRATION labels ISSUES overview suggestions
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Numerical Methods for Boundary Value Problems in Variable Coefficient Ordinary Differential Equations
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作者 ZHAO Ting-ting CAI Wei-yun 《Chinese Quarterly Journal of Mathematics》 2025年第3期295-303,共9页
In order to solve the problem of the variable coefficient ordinary differen-tial equation on the bounded domain,the Lagrange interpolation method is used to approximate the exact solution of the equation,and the error... In order to solve the problem of the variable coefficient ordinary differen-tial equation on the bounded domain,the Lagrange interpolation method is used to approximate the exact solution of the equation,and the error between the numerical solution and the exact solution is obtained,and then compared with the error formed by the difference method,it is concluded that the Lagrange interpolation method is more effective in solving the variable coefficient ordinary differential equation. 展开更多
关键词 Variable coefficient ordinary differential equations Lagrange interpolation Difference methods
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Continuous-Time Channel Prediction Based on Tensor Neural Ordinary Differential Equation
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作者 Mingyao Cui Hao Jiang +2 位作者 Yuhao Chen Yang Du Linglong Dai 《China Communications》 SCIE CSCD 2024年第1期163-174,共12页
Channel prediction is critical to address the channel aging issue in mobile scenarios.Existing channel prediction techniques are mainly designed for discrete channel prediction,which can only predict the future channe... Channel prediction is critical to address the channel aging issue in mobile scenarios.Existing channel prediction techniques are mainly designed for discrete channel prediction,which can only predict the future channel in a fixed time slot per frame,while the other intra-frame channels are usually recovered by interpolation.However,these approaches suffer from a serious interpolation loss,especially for mobile millimeter-wave communications.To solve this challenging problem,we propose a tensor neural ordinary differential equation(TN-ODE)based continuous-time channel prediction scheme to realize the direct prediction of intra-frame channels.Specifically,inspired by the recently developed continuous mapping model named neural ODE in the field of machine learning,we first utilize the neural ODE model to predict future continuous-time channels.To improve the channel prediction accuracy and reduce computational complexity,we then propose the TN-ODE scheme to learn the structural characteristics of the high-dimensional channel by low-dimensional learnable transform.Simulation results show that the proposed scheme is able to achieve higher intra-frame channel prediction accuracy than existing schemes. 展开更多
关键词 channel prediction massive multipleinput-multiple-output millimeter-wave communications ordinary differential equation
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The Boundary Element Method for Ordinary State-Based Peridynamics
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作者 Xue Liang Linjuan Wang 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第6期2807-2834,共28页
The peridynamics(PD),as a promising nonlocal continuum mechanics theory,shines in solving discontinuous problems.Up to now,various numerical methods,such as the peridynamic mesh-free particlemethod(PD-MPM),peridynamic... The peridynamics(PD),as a promising nonlocal continuum mechanics theory,shines in solving discontinuous problems.Up to now,various numerical methods,such as the peridynamic mesh-free particlemethod(PD-MPM),peridynamic finite element method(PD-FEM),and peridynamic boundary element method(PD-BEM),have been proposed.PD-BEM,in particular,outperforms other methods by eliminating spurious boundary softening,efficiently handling infinite problems,and ensuring high computational accuracy.However,the existing PD-BEM is constructed exclusively for bond-based peridynamics(BBPD)with fixed Poisson’s ratio,limiting its applicability to crack propagation problems and scenarios involving infinite or semi-infinite problems.In this paper,we address these limitations by introducing the boundary element method(BEM)for ordinary state-based peridynamics(OSPD-BEM).Additionally,we present a crack propagationmodel embeddedwithin the framework ofOSPD-BEM to simulate crack propagations.To validate the effectiveness of OSPD-BEM,we conduct four numerical examples:deformation under uniaxial loading,crack initiation in a double-notched specimen,wedge-splitting test,and threepoint bending test.The results demonstrate the accuracy and efficiency of OSPD-BEM,highlighting its capability to successfully eliminate spurious boundary softening phenomena under varying Poisson’s ratios.Moreover,OSPDBEMsignificantly reduces computational time and exhibits greater consistencywith experimental results compared to PD-MPM. 展开更多
关键词 ordinary state-based peridynamics boundary element method crack propagation fracture toughness
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The Hyers-Ulam Stability and Hyers-Ulam Instability for Some Nonhomogeneous Ordinary Differential Equations
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作者 DENG Jing-tao 《Chinese Quarterly Journal of Mathematics》 2024年第4期420-430,共11页
In this paper,we get a necessary and sufficient condition such that a class of differential inequalities hold.Using this necessary and sufficient condition,we prove that a class of first order nonhomogeneous ordinary ... In this paper,we get a necessary and sufficient condition such that a class of differential inequalities hold.Using this necessary and sufficient condition,we prove that a class of first order nonhomogeneous ordinary differential equations have the Hyers-Ulam stability.And then,we prove that some first order nonhomogeneous ordinary differential equations and some second order nonhomogeneous ordinary differential equations do not have the Hyers-Ulam instability under some suitable conditions. 展开更多
关键词 Hyers-Ulam stability Hyers-Ulam instability ordinary differential equations Necessary and sufficient condition
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Statistical study of mechanical responses of ordinary refractory ceramics under cold crushing condition with discrete element modelling
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作者 Wei-liang Du Sheng-li Jin 《Journal of Iron and Steel Research International》 CSCD 2024年第12期2971-2980,共10页
Ordinary refractory ceramics are multi-phase materials,and their inhomogeneous microstructures induce the scatter of properties.The definition of a reasonable number of samples is important to obtain representative re... Ordinary refractory ceramics are multi-phase materials,and their inhomogeneous microstructures induce the scatter of properties.The definition of a reasonable number of samples is important to obtain representative results from experiments and simulations,and this reasonable number might be property or microstructure relevant.Stochastic discrete element(DE)simulations of cold crushing tests with homogeneous interface properties were performed.Three minimum DE size ranges were used to represent matrix variation at different levels.Statistical methods,i.e.,Kolmogorov–Smirnov(K–S)test,t-test,and correlation analysis,were utilized to study the influences of minimal number of samples on mechanical properties and crack density.It revealed that a relatively small number of samples are sufficient to obtain representative cold crushing strength(CCS)and Young’s modulus,whilst a large number of samples are favourable when the fracture energy and crack density under cold crushing conditions are of interest.The analysis also showed that the fracture energy under cold crushing condition generally correlates positively with CCS,and the static Young’s moduli determined from the stress–piston displacement curves with different definitions are divergent,caused by contact compliance and premature cracking.The data from the stress–strain curves recorded directly on the sample are required for the accurate static Young’s modulus calculation. 展开更多
关键词 Discrete element method Statistic analysis ordinary refractory ceramics Minimal sample number Mechanical property
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Exploration of the Review Standards of Safety Assessment Reports for Ordinary Cosmetics
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作者 Yang Yumei Qi Dongmei +2 位作者 Li Rui Liu Zelong Yu Chunyuan 《China Detergent & Cosmetics》 CAS 2024年第4期18-29,共12页
Cosmetic safety assessment has distinct characteristics of interdisciplinary and extensive intersection,intensive technical knowledge,and high professional requirements.China is confronted with problems such as a lack... Cosmetic safety assessment has distinct characteristics of interdisciplinary and extensive intersection,intensive technical knowledge,and high professional requirements.China is confronted with problems such as a lack of professional safety assessment personnel and review personnel for cosmetic safety assessment.The compliance of safety assessment reports has become one of the important factors affecting the process of cosmetic filing and listing.This article contains the comprehensive analysis on the requirements of relevant regulations and technical documents for cosmetic safety assessment,as well as the judgment principles,and specific requirements of safety assessment reports.The key issues in current cosmetic safety assessment and the safety assessment requirements for typical products also are being focused on,so as to help standardize and unify the review standards of cosmetic safety assessment report,and provide reference for cosmetic filers. 展开更多
关键词 ordinary cosmetics safety assessment review standards typical product
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New Numerical Integration Formulations for Ordinary Differential Equations
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作者 Serdar Beji 《Advances in Pure Mathematics》 2024年第8期650-666,共17页
An entirely new framework is established for developing various single- and multi-step formulations for the numerical integration of ordinary differential equations. Besides polynomials, unconventional base-functions ... An entirely new framework is established for developing various single- and multi-step formulations for the numerical integration of ordinary differential equations. Besides polynomials, unconventional base-functions with trigonometric and exponential terms satisfying different conditions are employed to generate a number of formulations. Performances of the new schemes are tested against well-known numerical integrators for selected test cases with quite satisfactory results. Convergence and stability issues of the new formulations are not addressed as the treatment of these aspects requires a separate work. The general approach introduced herein opens a wide vista for producing virtually unlimited number of formulations. 展开更多
关键词 Single- and Multi-Step Numerical Integration Unconventional Base-Functions ordinary Differential Equations
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Research on the Change Path of Ordinary High School From the Perspective of Transformational Leadership——Take the No.4 High School of Xi’an High-tech Zone as an Example
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作者 Jianghua Chen 《Journal of Educational Theory and Management》 2024年第4期69-76,共8页
The Guiding Opinions of The General Office of the State Council on Promoting the Reform of ordinary high school education Mode in the New Era directly refers to the reform of ordinary high school education mode,making... The Guiding Opinions of The General Office of the State Council on Promoting the Reform of ordinary high school education Mode in the New Era directly refers to the reform of ordinary high school education mode,making it a new era mission of ordinary high school education development.The reform of ordinary high school is a complex and purposeful event,and the process of reform needs to go through several stages,each stage is faced with unique tasks,contradictions and corresponding strategies of change.As a principal,he must be clear about the goal of the school towards the future,the specific problems he needs to face and the corresponding strategies,and how to promote the overall reform of the school.What is the path of change?The proposal of transformational leadership theory provides a new way of thinking for opening the new situation of school reform.How to learn from the transformational leadership theory to seek an endogenous road for the reform of ordinary high school in our country in the complex contemporary educational environment is an important issue worth educators to study. 展开更多
关键词 ordinary high school CHANGE LEADERSHIP PERSPECTIVE MOTIVATION Care
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Petrography and classification of Elephant Moraine 14017 (EET 14017): a new primitive LL3.05 ordinary chondrite from Antarctica
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作者 Changkun Park Sun Young Park +1 位作者 Hwayoung Kim Jong Ik Lee 《Episodes》 2024年第3期465-476,共12页
The mineralogy and petrography of EET 14017 were studied using optical microscope,scanning electron microscope,electron microprobe,and micro-Raman.The mineral chemistry of olivine,pyroxene,plagioclase,spinel,and Fe-Ni... The mineralogy and petrography of EET 14017 were studied using optical microscope,scanning electron microscope,electron microprobe,and micro-Raman.The mineral chemistry of olivine,pyroxene,plagioclase,spinel,and Fe-Ni metal in EET 14017 is comparable to that of previously studied L/LL3.0x chondrites.In particular,the Cr2O3 content in the ferroan chondrule olivine and the excess silica component,[]Si4O8,in the plagioclase lead us to conclude that EET 14017 belongs to subtype 3.05.Raman spectral data of carbonaceous matter from the matrix of EET 14017 suggest a higher degree of thermal metamorphism,probably due to terrestrial weathering in Antarctica.EET 14017 and some of the other L/LL3.0x chondrites from the EET region are possibly a pair,since they have similar Cr2O3 contents of ferroan chondrule olivines and Raman spectral data,and moreover they were also found in a restricted region of the blue ice field.The plagioclase in some chondrules is a late crystal phase in the chondrule melt,which may constrain the timing of chondrule formation and cooling rate.If more L/LL3.0x chondrites like EET 14017 from Antarctica are identified,they would be excellent source material for studying the early evolution of the Solar System. 展开更多
关键词 ferroan chondrule olivine PETROGRAPHY mineral chemistry primitive LL ordinary chondrite
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Refraction of extraordinary rays and ordinary rays in the Savart polariscope 被引量:3
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作者 吴俊芳 张淳民 +2 位作者 张英堂 刘汉臣 翟学军 《Chinese Physics B》 SCIE EI CAS CSCD 2008年第7期2504-2508,共5页
The refraction of rays in the Savart polariscope is different from the isotropic medium. We have analysed and discussed the refraction of rays in the Savart polariscope on the basis of the Snell law. The refraction fo... The refraction of rays in the Savart polariscope is different from the isotropic medium. We have analysed and discussed the refraction of rays in the Savart polariscope on the basis of the Snell law. The refraction formulae of the extraordinary rays and ordinary rays were derived. Results obtained may provide theoretical and practical guide lines for studying, developing and engineering of polarization interference imaging spectrometer. 展开更多
关键词 Savart polariscope REFRACTION Snell law extraordinary rays ordinary rays
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On the Ratios Dark Matter (Energy)/Ordinary Matter ≈5.4(13.6) in the Universe
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作者 F. C. Hoh 《Journal of Modern Physics》 2020年第7期967-975,共9页
An upper limit of the average ratio dark matter/ordinary matter in galaxies is estimated to be 8.4, in agreement with the observed ratio 5.4. Upper limit of the average ratio dark energy/ordinary matter for slowly mov... An upper limit of the average ratio dark matter/ordinary matter in galaxies is estimated to be 8.4, in agreement with the observed ratio 5.4. Upper limit of the average ratio dark energy/ordinary matter for slowly moving protons in the outer parts of the universe is estimated to be 8.4, much less than the observed ratio 13.6. The discrepancy is tentatively attributed to that the bulk of the protons in these outer parts of the universe moves fastly and their contribution to dark energy has not been estimated. The positive and negative relative energies between the diquark and quark in the proton play the roles of dark energy and dark matter, respectively. 展开更多
关键词 Relative Energy Between Quarks Scalar Strong Interaction Hadron Theory Ratio of Dark Matter to ordinary Matter Ratio of Dark Energy to ordinary Matter Gravitational Pull of Diquark and Quark Proton Orbit Diquark Equations
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An "Ordinary" Man Sees Extraordinary Changes
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作者 By staff reporter LI FUGEN 《China Today》 1999年第10期34-35,共2页
关键词 Man Sees Extraordinary Changes AN ordinary
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The Durability of Alkali-Activated Materials in Comparison with Ordinary Portland Cements and Concretes:A Review 被引量:24
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作者 Aiguo Wang Yi Zheng +4 位作者 Zuhua Zhang Kaiwei Liu Yan Li Liang Shi Daosheng Sun 《Engineering》 SCIE EI 2020年第6期695-706,共12页
China is the largest producer and user of ordinary Portland cement(OPC),and the rapid growth of infrastructure development demands more sustainable building materials for concrete structures.Alkali-activated materials... China is the largest producer and user of ordinary Portland cement(OPC),and the rapid growth of infrastructure development demands more sustainable building materials for concrete structures.Alkali-activated materials(AAMs)are a new type of energy-saving and environmentally friendly building material with a wide range of potential applications.This paper compares the durability of AAMs and 0 PC-based materials un der sulfate attack,acid corrosion,carb on ation,and chloride penetratio n.Different AAMs have shown distinct durability properties due to different compositions being formed when different raw materials are used.According to the calcium(Ca)concentration of the raw materials,this paper interprets the deterioration mechanisms of three categories of AAMs:calcium-free,low-calcium,and calcium-rich.Conflicts found in the most recent research are highlighted,as they raise concerns regarding the consistenee and long-term properties of AAMs.Nevertheless,AAMs show better durability performances than OPC-based materials in general. 展开更多
关键词 Alkali-activated materials GEOPOLYMER DURABILITY ordinary Portland cement Deterioration mechanism
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Classification of 24 New Ordinary Chondrites from the Grove Mountains, Antarctica 被引量:13
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作者 LURen MIAOBingkui +4 位作者 WANGGuiqing DAIDeqiu LINYangting OUYANGZiyuan LIChunlai 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2004年第5期1052-1059,共8页
Petrography and mineral chemistry of 24 ordinary chondrites from the Grove Mountains, Antarctica, have been studied in order to identify their chemical-petrographic types. These samples were selected from a total of 4... Petrography and mineral chemistry of 24 ordinary chondrites from the Grove Mountains, Antarctica, have been studied in order to identify their chemical-petrographic types. These samples were selected from a total of 4448 Grove Mountains (GRV) meteorites collected during the 19th Chinese Antarctic Research Expedition so as to make an estimation of the large GRV meteorite collection. The chemical-petrographic types of these meteorites are presented below: 1 H3,2 H4, 4 H5, 2 H6, 1 L4, 7 L5, 5 L6, 1 LL4 and 1 LL6. The new data weaken the previous report that unequilibrated ordinary chondrites are unusually abundant in the Grove Mountains region. However, this work confirms significant differences in distribution patterns of chemical-petrographic types between the Grove Mountains and other regions in Antarctica. Many of these meteorites show significant terrestrial weathering, probably due to a high abundance ratio of meteorites found in moraines to those on blue ice. Nine meteorites experienced severe shock metamorphism, as evidenced by undulose extinction and intense fracturing of silicates and presence of shock-induced melt veins and pockets. These heavily shocked meteorites provided us with natural samples for the study of high-pressure polymorphs of minerals. 展开更多
关键词 ANTARCTICA METEORITE ordinary chondrite CLASSIFICATION shock metamorphism thermal metamorphism
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New Derivation of Ordinary Differential Equations for Transient Free-Surface Green Functions 被引量:15
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作者 段文洋 戴遗山 《China Ocean Engineering》 SCIE EI 2001年第4期499-508,共9页
Based on the Laplace transform, a direct derivation of the ordinary differential equations for the three-dimensional transient free-surface Green function in marine hydrodynamics is presented. The results for the 3D G... Based on the Laplace transform, a direct derivation of the ordinary differential equations for the three-dimensional transient free-surface Green function in marine hydrodynamics is presented. The results for the 3D Green function and all its spatial derivatives are a set of fourth-order ordinary differential equations, which are identical with that of Clement (1998). All of these results may be used to accelerate numerical computation for the time-domain boundary element method in marine hydrodynamics. 展开更多
关键词 marine hydrodynamics TIME-DOMAIN Green function ordinary differential equation Laplace transform
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Mapping Soil Electrical Conductivity Using Ordinary Kriging Combined with Back-propagation Network 被引量:6
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作者 HUANG Yajie LI Zhen +4 位作者 YE Huichun ZHANG Shiwen ZHUO Zhiqing XING An HUANG Yuanfang 《Chinese Geographical Science》 SCIE CSCD 2019年第2期270-282,共13页
Accurate mapping of soil salinity and recognition of its influencing factors are essential for sustainable crop production and soil health. Although the influencing factors have been used to improve the mapping accura... Accurate mapping of soil salinity and recognition of its influencing factors are essential for sustainable crop production and soil health. Although the influencing factors have been used to improve the mapping accuracy of soil salinity, few studies have considered both aspects of spatial variation caused by the influencing factors and spatial autocorrelations for mapping. The objective of this study was to demonstrate that the ordinary kriging combined with back-propagation network(OK_BP), considering the two aspects of spatial variation, which can benefit the improvement of the mapping accuracy of soil salinity. To test the effectiveness of this approach, 70 sites were sampled at two depths(0–30 and 30–50 cm) in Ningxia Hui Autonomous Region, China. Ordinary kriging(OK), back-propagation network(BP) and regression kriging(RK) were used in comparison analysis; the root mean square error(RMSE), relative improvement(RI) and the decrease in estimation imprecision(DIP) were used to judge the mapping quality. Results showed that OK_BP avoided the both underestimation and overestimation of the higher and lower values of interpolation surfaces. OK_BP revealed more details of the spatial variation responding to influencing factors, and provided more flexibility for incorporating various correlated factors in the mapping. Moreover, OK_BP obtained better results with respect to the reference methods(i.e., OK, BP, and RK) in terms of the lowest RMSE, the highest RI and DIP. Thus, it is concluded that OK_BP is an effective method for mapping soil salinity with a high accuracy. 展开更多
关键词 ordinary KRIGING NEURAL network SOIL electrical CONDUCTIVITY VARIABILITY MAPPING Ningxia China
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Effects of fibers on expansive shotcrete mixtures consisting of calcium sulfoaluminate cement,ordinary Portland cement,and calcium sulfate 被引量:7
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作者 H.Yu L.Wu +1 位作者 W.V.Liu Y.Pourrahimian 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2018年第2期212-221,共10页
The mining industry often uses shotcrete for ground stabilization. However, cracking within shotcrete is commonly observed, which delays production schedules and increases maintenance costs. A possible crack reduction... The mining industry often uses shotcrete for ground stabilization. However, cracking within shotcrete is commonly observed, which delays production schedules and increases maintenance costs. A possible crack reduction method is using expansive shotcrete mixture consisting of calcium sulfoaluminate cement(CSA), ordinary Portland cement(OPC), and calcium sulfate(CS) to reduce shrinkage. Furthermore, fibers can be added to the mixture to restrain expansion and impede cracking. The objective of this paper is to study the effects of nylon fiber, glass fiber, and steel fiber on an expansive shotcrete mixture that can better resist cracking. In this study, parameters such as density, water absorption, volume of permeable voids, unconfined compressive strength(UCS), splitting tensile strength(STS), and volume change of fiber-added expansive mixtures were determined at different time periods(i.e. the strengths on the 28 th day, and the volume changes on the 1 st, 7 th, 14 th, 21 st, and 28 th days). The results show that addition of fibers can improve mixture durability, in the form of decreased water absorption and reduced permeable pore space content. Moreover, the expansion of the CSA-OPC-CS mixture was restrained up to50% by glass fiber, up to 43% by nylon fiber, and up to 28% by steel fiber. The results show that the STS was improved by 57% with glass fiber addition, 43% with steel fiber addition, and 38% with nylon fiber addition. The UCS was also increased by 31% after steel fiber addition, 26% after nylon fiber addition, and16% after glass fiber addition. These results suggest that fiber additions to the expansive shotcrete mixtures can improve durability and strengths while controlling expansion. 展开更多
关键词 SHOTCRETE Restrained expansion Fibers Calcium sulfoaluminate cement(CSA) ordinary Portland cement(OPC) Calcium sulfate(CS)
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HIGH ACCURACY FINITE VOLUME ELEMENT METHOD FOR TWO-POINT BOUNDARY VALUE PROBLEM OF SECOND ORDER ORDINARY DIFFERENTIAL EQUATIONS 被引量:4
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作者 Wang Tongke(王同科) 《Numerical Mathematics A Journal of Chinese Universities(English Series)》 SCIE 2002年第2期213-225,共13页
In this paper, a high accuracy finite volume element method is presented for two-point boundary value problem of second order ordinary differential equation, which differs from the high order generalized difference me... In this paper, a high accuracy finite volume element method is presented for two-point boundary value problem of second order ordinary differential equation, which differs from the high order generalized difference methods. It is proved that the method has optimal order error estimate O(h3) in H1 norm. Finally, two examples show that the method is effective. 展开更多
关键词 SECOND order ordinary differential equation TWO-POINT boundary value problem high accuracy finite volume element method error estimate.
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Role of detection of microsatellite instability in Chinese with hereditary nonpolyposis colorectal cancer or ordinary hereditary colorectal cancer 被引量:5
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作者 Wen-Zhi Liu Feng Jin +1 位作者 Zhen-Hai Zhang Shu-Bao Wang 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第29期4745-4749,共5页
AIM: To detect microsatellite instability (MSI) in patients with hereditary nonpolyposis colorectal cancer or ordinary hereditary colorectal cancer and to provide criteria for screening the kindreds with hereditary... AIM: To detect microsatellite instability (MSI) in patients with hereditary nonpolyposis colorectal cancer or ordinary hereditary colorectal cancer and to provide criteria for screening the kindreds with hereditary nonpolyposis colorectal cancer at molecular level.METHODS: MSI was detected in the specimens from 20 cases with HNPCC, 20 cases with ordinary hereditary colorectal cancer and 20 cases with sporadic colorectal cancer by means of polymerase chain reaction-single strand conformation polymorphism. RESULTS: The positive rate of MSI was 85% (17/20) in HNPCC group, 40% (8/20) in ordinary hereditary colorectal cancer group and 10% (2/20) in the sporadic colorectal cancer group respectively. The differences were significant. The mean ages of the three groups were 43.6, 52.2, and 61.8 years respectively, which increased gradually. The incidence of right hemicolon cancer was 64.7%, 37.5%, and 0% respectively, which decreased gradually and had significant difference. The expression ratio of BAT26 and BAT25 was 94.1% respectively, which was highest in the 5 gene sites studied. The incidence of poorly differentiated adenocarcinoma was 70.6% in HNPCC group among high frequency microsatellite instability (MSI-H), which was higher than the other two groups, which had 50% and 50% respectively. CONCLUSION: The incidence of MSI-H is higher in HNPCC group. The detection of MSI is simple and economical and has high correlation with the clinicopathologic feature of HNPCC and can be used as a screening method to detect the germ line mutation of the mismatch repair gene. 展开更多
关键词 Hereditary nonpolyposis colorectal cancer Microsatellite instability ordinary hereditary colorec-tal cancer Single strand conformation polymorphism Polymerase chain reaction
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