Role-play is recommended as a useful method to solve the problem of oral English teaching. It's much more than a performance and it can be considered as a way to vary the kinds of spoken interaction that learners ...Role-play is recommended as a useful method to solve the problem of oral English teaching. It's much more than a performance and it can be considered as a way to vary the kinds of spoken interaction that learners can experience in the classroom of universities. Through the use of role-play, oral English teaching becomes more interesting and attractive; university students can gain more oral English skills in the mini society atmosphere, and the accuracy and fluency of their oral English will be improved.展开更多
This paper is to evaluate postoperative function which has undergone reconstruction with vascularized or pedicled flaps for the treatment of oral carcinomas. The subjects consisted of 22 cases of 17 male and 5 female ...This paper is to evaluate postoperative function which has undergone reconstruction with vascularized or pedicled flaps for the treatment of oral carcinomas. The subjects consisted of 22 cases of 17 male and 5 female patients, and their mean age was 55 years. The sites of reconstruction were the tongue in 12 cases, mandible in 10 cases. The reconstruction was performed using deltopectoral (DP) flaps in 6 cases, pectoralis major musculo cutaneous (PMMC) flaps in 3 cases, DP flap + PMMC flap in one case, forearm (FA) flaps in 8 cases and peroneal (P) flaps with fibula in 4 cases. Postoperative masticatory, speech, swallowing functions and facial appearance were evaluated by Multi-factorial analysis. All functional results seem to be related to the type of resection. By multi-factorial analysis, the type of mandibular resection, flap area, and anterior resection were related to the masticatory or speech function in tongue resection. In mandibular resection, masticatory function was subjected to age;speech function was subjected to type of mandibular resection and plate reconstruction. The facial appearance was subjected to flap area. These results suggested that postoperative function was not related to only one factor, but using the classification of each defect site as one of the factor of multi-factorial analysis was useful.展开更多
<b><span style="font-family:"">Objective</span></b><span style="font-family:"">: Oral diadochokinesis (ODK) has been shown to be associated with oral frailty...<b><span style="font-family:"">Objective</span></b><span style="font-family:"">: Oral diadochokinesis (ODK) has been shown to be associated with oral frailty. In this study, we investigate the relationship between physical function, swallowing function, nutritional evaluation, and each syllable of ODK. <b>Methods</b>: The subjects are 26 elderly people living in an area where <span>they can walk. ODK, tongue pressure, modified water swallowing test, EAT-10,</span> grip strength, MNA-SF, skeletal muscle index, height, weight, and BMI were evaluated. For statistical analysis based on ODK values, the subjects were divided into two groups on the basis of the number of times the syllables /pa/, /ta/, and /ka/ were repeated: 1) The first group with >6 repetitions exceeded six</span><span style="font-family:"">;</span><span style="font-family:""> 2) the second group with ≤5 repetitions. Both groups were compared using the Mann-Whitney U test (Model 1). In addition, the syllables /pa/, /ta/, and /ka/ were also divided among the groups and a comparison was performed (Model 2). <b>Results</b>: In Model 1, the tongue pressure value was significantly higher in the good group (p < 0.01). In Model 2, the good group showed significantly higher values for the syllables /pa/ (p < 0.01) and /ta/ (p < 0.05). There was no significant difference in the values for the syllable /ka/. <b>Conclusion</b>: In community-dwelling elderly people, tongue pressure was positively associated with ODK values for the syllables /pa/ and /ta/, suggesting that tongue pressure may be associated with strength of the lip and tongue tip muscles. Furthermore, it was suggested that the ODK values may even be lower than normal values in the elderly who maintain skeletal muscle mass and thus have adequate tongue pressure;therefore, these indicators may be used as a guideline to assess oral frailty.展开更多
The effects on immune function of broilers was studied by adding different doses of Shuanghuanglian propolis oral liquid in drinking water, to provide a theoretical basis for application and promotion of Shuanghuangli...The effects on immune function of broilers was studied by adding different doses of Shuanghuanglian propolis oral liquid in drinking water, to provide a theoretical basis for application and promotion of Shuanghuanglian propolis oral liquid. Ninety one-day-old broilers were randomly divided into three groups ： group I was designed as control; groups Ⅱ and Ⅲ were added with 0.5 and 1.0 mL/L Shuanghuanglian propolis oral liquid in drinking water, respectively. Compared with group I, all tested indicators in groups Ⅱ and Ⅲ were increased at varying degrees as follows ： bursa of fabricius index increased by 5.74% （P 〈 0.05 ） and 7.66% （P 〈 0.05 ） ; thymus index increased by 1.47% （P 〉 0.05 ） and 2.06% （P 〈 0.05 ） ; spleen index increased by 5.88% （P 〉 0.05 ） and 7.84% （ P 〈 0.05 ） ; Newcastle disease virus （NDV） antibody titer increased by 11.99% （P 〈 0.05 ） and 16.94% （P 〈 0.05 ） ; IL-2 content increased by 2.71% （P 〉 0.05） and 4.52% （P 〈 0.05 ） ; IL -6 content increased by 4.04% （P 〉 0.05 ） and 7.26% （ P 〈 0.05 ）, respectively. The results showed that adding 0.5 and 1.0 mL/L Shuanghuangllan propolis oral liquid in drinking water could improve the immune function of broiler and immune effect of ND vaccine.展开更多
[Objective] The study aimed to explore the effects of Zizhuliqing Oral Liquid on animal cellular immune function.[Method] MTT method and phagocytizing natural red method were used to determine the effects of Zizhuliqi...[Objective] The study aimed to explore the effects of Zizhuliqing Oral Liquid on animal cellular immune function.[Method] MTT method and phagocytizing natural red method were used to determine the effects of Zizhuliqing Oral Liquid on piglet lymphocyte transformation and the phagocytosis of mouse peritoneal macrophages respectively.[Result] The lymphocyte transformation rates of piglets in medicated groups were significantly higher than that in control group;the difference of mouse peritoneal macrophage activities between the medicated groups and the control group was obvious.[Conclusion] Zizhuliqing Oral Liquid could promote the transformation of piglet T lymphocytes induced by ConA and the phagocytosis of mouse peritoneal macrophages to natural red,indicating its good immune enhancement function.展开更多
Objective: The purpose of this study was to examine the effects of continuous gum chewing exercise on perioral muscle strength. Methods: Thirty healthy adults (24.1 ± 2.0 years) with normal occlusion performed gu...Objective: The purpose of this study was to examine the effects of continuous gum chewing exercise on perioral muscle strength. Methods: Thirty healthy adults (24.1 ± 2.0 years) with normal occlusion performed gum chewing exercise 3 times daily for 3 months. Each exercise session lasted 5 min and involved alternating of chewing 10 times using the left molars and then 10 times using the right molars, with the mouth closed. The effect of the exercise on oral function was evaluated by measuring tongue pressure (TP), cheek pressure (CP), and labial closure strength (LCS) immediately before starting exercise, at 2 weeks and 1, 2, and 3 months after starting exercise, and at 3 months after cessation of exercise. Changes in TP, CP, and LCS according to sex and duration of exercise were analyzed by repeated two-way ANOVA. Results: Measurements for all muscles were significantly greater in men than in women at all time points. After starting exercise, TP was markedly increased at 2 months in men and women, and both CP and LCS were markedly increased at 2 weeks in men and at 1 month in women. These effects persisted for 3 months. Three months after cessation of exercise, TP, CP, and LCS tended to decrease, but were not significantly attenuated as compared with 3 months after beginning of exercise in either sex. Conclusion: The results of this study revealed that gum chewing exercise contributed to an improvement in perioral muscle strength, and that this effect was maintained for at least 3 months after discontinuation of exercise.展开更多
Background: Resection of the mandible can lead to bony defect which has a direct bearing on the quality of life of the patient. Reconstruction of such defect is necessary to restore aesthetics but optimal functioning ...Background: Resection of the mandible can lead to bony defect which has a direct bearing on the quality of life of the patient. Reconstruction of such defect is necessary to restore aesthetics but optimal functioning of the oral cavity can only be achieved with prosthodontic rehabilitation. We, hereby, report the impact of oral rehabilitation on patients’ satisfaction and quality of life after mandibular reconstruction in our institution. Materials and Method: Patients who had oral rehabilitation following mandibular reconstruction from January 2010 to December 2015 were included. Patients’ oral health related quality of life [OHRQL] before and after rehabilitation was evaluated using the head and neck module of the European Organization for Research and Treatment of Cancer [EORTC]. Oral functions and denture satisfaction were also evaluated with Visual Analogue Scale [VAS]. Data obtained were analyzed with SPSS version 20 and level of significance was set at p Result: Of the 43 patients who had mandibular reconstruction during the study period, only 21 [48.8%] had dental rehabilitation. Twelve patients [57.1%] had conventional acrylic denture, 5 had fixed denture [bridge] while 4 patients had rehabilitation with dental implants. The mean follow-up period after rehabilitation was 8.42 months [Range: 6 - 22 months]. Although, OHRQL analysis revealed an improvement following rehabilitation, only the social aspect of the evaluation was statistically significant [p p = 0.00]. On the contrary, there was no statistically significant difference in aesthetics amongst the patients regardless of type of rehabilitation [p = 0.26]. Conclusion: Findings from this study showed that there is improvement in OHRQL following dental rehabilitation. Also, Patients who were rehabilitated with dental implant had better oral function than those with fixed or conventional denture.展开更多
Aim: To systematically evaluate the effects of colostrum intervention on gas-trointestinal function and related diseases in premature infants. Methods: A randomized controlled trial was conducted in the Cochrane Libra...Aim: To systematically evaluate the effects of colostrum intervention on gas-trointestinal function and related diseases in premature infants. Methods: A randomized controlled trial was conducted in the Cochrane Library, PubMed, EBSCO, CINAHL, Embase, Medline, CBMDISC, CNKI, Wan Fang and VIP databases on the effects of colostrum and oral intervention on gastrointestinal function and related diseases in premature infants. Literature screening, quality evaluation and data extraction were conducted, and data analysis was conducted using Revman 5.3. Results: A total of 7 references were included, including 392 subjects. The combined results showed that: colostrum can effectively reduce the incidence of nosocomial infection [RR = 0.42, 95% CI (0.25, 0.73), P = 0.002]. Conclusion: Colostrums oral intervention can effectively reduce the incidence of nosocomial infection in premature infants. However, there was no advantage in feeding intolerance, necrotizing enters colitis and length of hospital stay.展开更多
目的 检索、评价和整合老年人口腔衰弱管理的证据,为口腔衰弱的科学管理提供依据。方法 系统检索BMJ Best Practice、Up To Date、英国国家卫生与临床优化研究所网站、苏格兰校际指南网、世界牙科联盟网站、Web of Science、PubMed、Coc...目的 检索、评价和整合老年人口腔衰弱管理的证据,为口腔衰弱的科学管理提供依据。方法 系统检索BMJ Best Practice、Up To Date、英国国家卫生与临床优化研究所网站、苏格兰校际指南网、世界牙科联盟网站、Web of Science、PubMed、Cochrane Library、中国知网、万方数据库和其他专业相关网站。纳入老年人口腔衰弱相关指南、专家共识、证据总结、系统综述和随机对照试验。检索时限为建库至2024年1月24日。由2~3名研究者独立评价文献质量,提取和整合相关证据。结果 共纳入10篇文献,指南2篇,专家共识2篇,系统评价1篇,随机对照试验5篇。从口腔衰弱评估、口腔衰弱预防和口腔衰弱干预3个方面汇总13条最佳证据。结论 该研究总结的老年人口腔衰弱管理的证据具有科学性和实用性,医院、社区、养老机构等相关人员可以通过应用证据对老年人进行口腔衰弱的评估、预防及针对性的干预措施。展开更多
[Objective] The paper was to investigate the clinical effects of Nvhuang Fuzheng oral liquid on immunity enhancement,disease resistance and growth promotion of chicks. [Method] In the test,3-day-old Daninghe chicks we...[Objective] The paper was to investigate the clinical effects of Nvhuang Fuzheng oral liquid on immunity enhancement,disease resistance and growth promotion of chicks. [Method] In the test,3-day-old Daninghe chicks were divided into normal control group,Nvhuang Fuzheng oral liquid group and positive control group. Chicks were administrated with drugs for 7 d before immunization. After vaccination,chicks were observed for 4 weeks,to statistically count the incidence state of chicks. Effects of Nvhuang Fuzheng oral liquid on growth performance,serum immunoglobulin,cytokine and infectious bursal disease virus( IBDV)antibody were studied. [Result] Compared to normal control group,Nvhuang Fuzheng oral liquid significantly improved the weight of chicks and reduced the feed gain ratio( P < 0. 05); significantly reduced the morbidity and mortality and increased the survival rate of chicks( P < 0. 05); continuously increased IgG,IgM and IL-2 content significantly in the serum of chicks( P < 0. 05); extremely improved IFN-γ content in the serum at 7 d post drug administration( P < 0. 01). After vaccination of IBDV vaccine for 1 and 2 weeks,Nvhuang Fuzheng oral liquid significantly improved IBDV antibody titer and positive rate of chicks compared to normal control group( P < 0. 05); at 3 weeks post immunization,the antibody positive rate reached 100%. [Conclusion]Nvhuang Fuzheng oral liquid improved immunoglobulin and cytokine levels of chicks,enhanced the immunity and reduced the occurrence of diseases( the morbidity was reduced by 15% and the mortality was reduced by 30%),enhanced disease-resistant ability and promoted the growth of chicks. Meantime,it improved the immune effect of IBDV vaccine.展开更多
目的探讨老年脑卒中患者认知功能对口腔健康相关生活质量(oral health-related quality of life,OHRQoL)评估的影响及作用机制。方法采用横断面研究设计,采用便利抽样的方法于2015年10月至2020年1月从宣武医院、天坛医院、大兴区西红门...目的探讨老年脑卒中患者认知功能对口腔健康相关生活质量(oral health-related quality of life,OHRQoL)评估的影响及作用机制。方法采用横断面研究设计,采用便利抽样的方法于2015年10月至2020年1月从宣武医院、天坛医院、大兴区西红门医院和北京口腔医院门诊招募符合纳入和排除标准的老年脑卒中患者247例。根据蒙特利尔认知功能量表评分分为中重度认知障碍组111例(≤20分),轻度认知障碍组95例(21~25分),认知功能正常组41例(≥26分)。采用口腔健康影响程度量表简版(oral health impact prole-14,OHIP-14)评估OHRQoL,并进行标准化口腔临床检查及口腔情况认知功能测试。通过Mann-Whitney U检验比较不同认知功能组间差异,并构建结构方程模型进行路径分析。结果中重度认知障碍组OHIP-14评分中疼痛与不适维度及总分显著低于轻度认知障碍组(P<0.05)。路径分析显示,认知功能通过口腔情况认知功能的完全中介作用间接影响OHRQoL评估。结论中重度认知障碍的老年脑卒中患者可能因其口腔情况认知功能下降,造成其OHRQoL评估不准确。展开更多
文摘Role-play is recommended as a useful method to solve the problem of oral English teaching. It's much more than a performance and it can be considered as a way to vary the kinds of spoken interaction that learners can experience in the classroom of universities. Through the use of role-play, oral English teaching becomes more interesting and attractive; university students can gain more oral English skills in the mini society atmosphere, and the accuracy and fluency of their oral English will be improved.
文摘This paper is to evaluate postoperative function which has undergone reconstruction with vascularized or pedicled flaps for the treatment of oral carcinomas. The subjects consisted of 22 cases of 17 male and 5 female patients, and their mean age was 55 years. The sites of reconstruction were the tongue in 12 cases, mandible in 10 cases. The reconstruction was performed using deltopectoral (DP) flaps in 6 cases, pectoralis major musculo cutaneous (PMMC) flaps in 3 cases, DP flap + PMMC flap in one case, forearm (FA) flaps in 8 cases and peroneal (P) flaps with fibula in 4 cases. Postoperative masticatory, speech, swallowing functions and facial appearance were evaluated by Multi-factorial analysis. All functional results seem to be related to the type of resection. By multi-factorial analysis, the type of mandibular resection, flap area, and anterior resection were related to the masticatory or speech function in tongue resection. In mandibular resection, masticatory function was subjected to age;speech function was subjected to type of mandibular resection and plate reconstruction. The facial appearance was subjected to flap area. These results suggested that postoperative function was not related to only one factor, but using the classification of each defect site as one of the factor of multi-factorial analysis was useful.
文摘<b><span style="font-family:"">Objective</span></b><span style="font-family:"">: Oral diadochokinesis (ODK) has been shown to be associated with oral frailty. In this study, we investigate the relationship between physical function, swallowing function, nutritional evaluation, and each syllable of ODK. <b>Methods</b>: The subjects are 26 elderly people living in an area where <span>they can walk. ODK, tongue pressure, modified water swallowing test, EAT-10,</span> grip strength, MNA-SF, skeletal muscle index, height, weight, and BMI were evaluated. For statistical analysis based on ODK values, the subjects were divided into two groups on the basis of the number of times the syllables /pa/, /ta/, and /ka/ were repeated: 1) The first group with >6 repetitions exceeded six</span><span style="font-family:"">;</span><span style="font-family:""> 2) the second group with ≤5 repetitions. Both groups were compared using the Mann-Whitney U test (Model 1). In addition, the syllables /pa/, /ta/, and /ka/ were also divided among the groups and a comparison was performed (Model 2). <b>Results</b>: In Model 1, the tongue pressure value was significantly higher in the good group (p < 0.01). In Model 2, the good group showed significantly higher values for the syllables /pa/ (p < 0.01) and /ta/ (p < 0.05). There was no significant difference in the values for the syllable /ka/. <b>Conclusion</b>: In community-dwelling elderly people, tongue pressure was positively associated with ODK values for the syllables /pa/ and /ta/, suggesting that tongue pressure may be associated with strength of the lip and tongue tip muscles. Furthermore, it was suggested that the ODK values may even be lower than normal values in the elderly who maintain skeletal muscle mass and thus have adequate tongue pressure;therefore, these indicators may be used as a guideline to assess oral frailty.
文摘The effects on immune function of broilers was studied by adding different doses of Shuanghuanglian propolis oral liquid in drinking water, to provide a theoretical basis for application and promotion of Shuanghuanglian propolis oral liquid. Ninety one-day-old broilers were randomly divided into three groups ： group I was designed as control; groups Ⅱ and Ⅲ were added with 0.5 and 1.0 mL/L Shuanghuanglian propolis oral liquid in drinking water, respectively. Compared with group I, all tested indicators in groups Ⅱ and Ⅲ were increased at varying degrees as follows ： bursa of fabricius index increased by 5.74% （P 〈 0.05 ） and 7.66% （P 〈 0.05 ） ; thymus index increased by 1.47% （P 〉 0.05 ） and 2.06% （P 〈 0.05 ） ; spleen index increased by 5.88% （P 〉 0.05 ） and 7.84% （ P 〈 0.05 ） ; Newcastle disease virus （NDV） antibody titer increased by 11.99% （P 〈 0.05 ） and 16.94% （P 〈 0.05 ） ; IL-2 content increased by 2.71% （P 〉 0.05） and 4.52% （P 〈 0.05 ） ; IL -6 content increased by 4.04% （P 〉 0.05 ） and 7.26% （ P 〈 0.05 ）, respectively. The results showed that adding 0.5 and 1.0 mL/L Shuanghuangllan propolis oral liquid in drinking water could improve the immune function of broiler and immune effect of ND vaccine.
基金Supported by Scientific Research Project of Jiangsu Animal Husbandry&Veterinary College(200605)~~
文摘[Objective] The study aimed to explore the effects of Zizhuliqing Oral Liquid on animal cellular immune function.[Method] MTT method and phagocytizing natural red method were used to determine the effects of Zizhuliqing Oral Liquid on piglet lymphocyte transformation and the phagocytosis of mouse peritoneal macrophages respectively.[Result] The lymphocyte transformation rates of piglets in medicated groups were significantly higher than that in control group;the difference of mouse peritoneal macrophage activities between the medicated groups and the control group was obvious.[Conclusion] Zizhuliqing Oral Liquid could promote the transformation of piglet T lymphocytes induced by ConA and the phagocytosis of mouse peritoneal macrophages to natural red,indicating its good immune enhancement function.
文摘Objective: The purpose of this study was to examine the effects of continuous gum chewing exercise on perioral muscle strength. Methods: Thirty healthy adults (24.1 ± 2.0 years) with normal occlusion performed gum chewing exercise 3 times daily for 3 months. Each exercise session lasted 5 min and involved alternating of chewing 10 times using the left molars and then 10 times using the right molars, with the mouth closed. The effect of the exercise on oral function was evaluated by measuring tongue pressure (TP), cheek pressure (CP), and labial closure strength (LCS) immediately before starting exercise, at 2 weeks and 1, 2, and 3 months after starting exercise, and at 3 months after cessation of exercise. Changes in TP, CP, and LCS according to sex and duration of exercise were analyzed by repeated two-way ANOVA. Results: Measurements for all muscles were significantly greater in men than in women at all time points. After starting exercise, TP was markedly increased at 2 months in men and women, and both CP and LCS were markedly increased at 2 weeks in men and at 1 month in women. These effects persisted for 3 months. Three months after cessation of exercise, TP, CP, and LCS tended to decrease, but were not significantly attenuated as compared with 3 months after beginning of exercise in either sex. Conclusion: The results of this study revealed that gum chewing exercise contributed to an improvement in perioral muscle strength, and that this effect was maintained for at least 3 months after discontinuation of exercise.
文摘Background: Resection of the mandible can lead to bony defect which has a direct bearing on the quality of life of the patient. Reconstruction of such defect is necessary to restore aesthetics but optimal functioning of the oral cavity can only be achieved with prosthodontic rehabilitation. We, hereby, report the impact of oral rehabilitation on patients’ satisfaction and quality of life after mandibular reconstruction in our institution. Materials and Method: Patients who had oral rehabilitation following mandibular reconstruction from January 2010 to December 2015 were included. Patients’ oral health related quality of life [OHRQL] before and after rehabilitation was evaluated using the head and neck module of the European Organization for Research and Treatment of Cancer [EORTC]. Oral functions and denture satisfaction were also evaluated with Visual Analogue Scale [VAS]. Data obtained were analyzed with SPSS version 20 and level of significance was set at p Result: Of the 43 patients who had mandibular reconstruction during the study period, only 21 [48.8%] had dental rehabilitation. Twelve patients [57.1%] had conventional acrylic denture, 5 had fixed denture [bridge] while 4 patients had rehabilitation with dental implants. The mean follow-up period after rehabilitation was 8.42 months [Range: 6 - 22 months]. Although, OHRQL analysis revealed an improvement following rehabilitation, only the social aspect of the evaluation was statistically significant [p p = 0.00]. On the contrary, there was no statistically significant difference in aesthetics amongst the patients regardless of type of rehabilitation [p = 0.26]. Conclusion: Findings from this study showed that there is improvement in OHRQL following dental rehabilitation. Also, Patients who were rehabilitated with dental implant had better oral function than those with fixed or conventional denture.
文摘Aim: To systematically evaluate the effects of colostrum intervention on gas-trointestinal function and related diseases in premature infants. Methods: A randomized controlled trial was conducted in the Cochrane Library, PubMed, EBSCO, CINAHL, Embase, Medline, CBMDISC, CNKI, Wan Fang and VIP databases on the effects of colostrum and oral intervention on gastrointestinal function and related diseases in premature infants. Literature screening, quality evaluation and data extraction were conducted, and data analysis was conducted using Revman 5.3. Results: A total of 7 references were included, including 392 subjects. The combined results showed that: colostrum can effectively reduce the incidence of nosocomial infection [RR = 0.42, 95% CI (0.25, 0.73), P = 0.002]. Conclusion: Colostrums oral intervention can effectively reduce the incidence of nosocomial infection in premature infants. However, there was no advantage in feeding intolerance, necrotizing enters colitis and length of hospital stay.
文摘目的 检索、评价和整合老年人口腔衰弱管理的证据,为口腔衰弱的科学管理提供依据。方法 系统检索BMJ Best Practice、Up To Date、英国国家卫生与临床优化研究所网站、苏格兰校际指南网、世界牙科联盟网站、Web of Science、PubMed、Cochrane Library、中国知网、万方数据库和其他专业相关网站。纳入老年人口腔衰弱相关指南、专家共识、证据总结、系统综述和随机对照试验。检索时限为建库至2024年1月24日。由2~3名研究者独立评价文献质量,提取和整合相关证据。结果 共纳入10篇文献,指南2篇,专家共识2篇,系统评价1篇,随机对照试验5篇。从口腔衰弱评估、口腔衰弱预防和口腔衰弱干预3个方面汇总13条最佳证据。结论 该研究总结的老年人口腔衰弱管理的证据具有科学性和实用性,医院、社区、养老机构等相关人员可以通过应用证据对老年人进行口腔衰弱的评估、预防及针对性的干预措施。
基金Supported by Basic Scientific Research Fund of Chongqing City(16423)
文摘[Objective] The paper was to investigate the clinical effects of Nvhuang Fuzheng oral liquid on immunity enhancement,disease resistance and growth promotion of chicks. [Method] In the test,3-day-old Daninghe chicks were divided into normal control group,Nvhuang Fuzheng oral liquid group and positive control group. Chicks were administrated with drugs for 7 d before immunization. After vaccination,chicks were observed for 4 weeks,to statistically count the incidence state of chicks. Effects of Nvhuang Fuzheng oral liquid on growth performance,serum immunoglobulin,cytokine and infectious bursal disease virus( IBDV)antibody were studied. [Result] Compared to normal control group,Nvhuang Fuzheng oral liquid significantly improved the weight of chicks and reduced the feed gain ratio( P < 0. 05); significantly reduced the morbidity and mortality and increased the survival rate of chicks( P < 0. 05); continuously increased IgG,IgM and IL-2 content significantly in the serum of chicks( P < 0. 05); extremely improved IFN-γ content in the serum at 7 d post drug administration( P < 0. 01). After vaccination of IBDV vaccine for 1 and 2 weeks,Nvhuang Fuzheng oral liquid significantly improved IBDV antibody titer and positive rate of chicks compared to normal control group( P < 0. 05); at 3 weeks post immunization,the antibody positive rate reached 100%. [Conclusion]Nvhuang Fuzheng oral liquid improved immunoglobulin and cytokine levels of chicks,enhanced the immunity and reduced the occurrence of diseases( the morbidity was reduced by 15% and the mortality was reduced by 30%),enhanced disease-resistant ability and promoted the growth of chicks. Meantime,it improved the immune effect of IBDV vaccine.
文摘目的探讨老年脑卒中患者认知功能对口腔健康相关生活质量(oral health-related quality of life,OHRQoL)评估的影响及作用机制。方法采用横断面研究设计,采用便利抽样的方法于2015年10月至2020年1月从宣武医院、天坛医院、大兴区西红门医院和北京口腔医院门诊招募符合纳入和排除标准的老年脑卒中患者247例。根据蒙特利尔认知功能量表评分分为中重度认知障碍组111例(≤20分),轻度认知障碍组95例(21~25分),认知功能正常组41例(≥26分)。采用口腔健康影响程度量表简版(oral health impact prole-14,OHIP-14)评估OHRQoL,并进行标准化口腔临床检查及口腔情况认知功能测试。通过Mann-Whitney U检验比较不同认知功能组间差异,并构建结构方程模型进行路径分析。结果中重度认知障碍组OHIP-14评分中疼痛与不适维度及总分显著低于轻度认知障碍组(P<0.05)。路径分析显示,认知功能通过口腔情况认知功能的完全中介作用间接影响OHRQoL评估。结论中重度认知障碍的老年脑卒中患者可能因其口腔情况认知功能下降,造成其OHRQoL评估不准确。
