Purpose:.Glaucoma is an eye disease that can lead to irreversible optic nerve damage and cause blindness. Optical coherence tomography.(OCT) allows an early diagnosis of glaucoma by the measurements of the retinal ner...Purpose:.Glaucoma is an eye disease that can lead to irreversible optic nerve damage and cause blindness. Optical coherence tomography.(OCT) allows an early diagnosis of glaucoma by the measurements of the retinal nerve fiber and optic disc parameters.A retrospective study was designed to analyze the effects of the measurement of the retinal nerve fiber layer(RNFL) thickness and the optic disc tomography by spectraldomain OCT on the early diagnosis of suspected glaucoma and primary open angle glaucoma(POAG).Methods:.This was a clinical case-control study. The RNFL thickness around the optic disc and optic disk tomographic parameters of the control(n=51, 98 eyes), suspected glaucoma(n=81,.146 eyes), and POAG groups(n=55, 106 eyes) were measured by OCT. The parameters included superior, inferior, nasal and temporal mean RNFL thickness,.disc area(DA), cup area(CA), rim area(RA), disc volume(DV),cup volume(CV), rim volume(RV), cup / disc area ratio(CA / DA), rim / disc area ratio(RA / DA), cup / disc volume ratio(CV / DV) and rim / disc volume ratio(RV / DV).Results: Superior, nasal, and mean RNFL parameters, DA,CA,RA, DV, CV, CA / DA, RA / DA, CV / DV and RV / DV significantly differed among three groups by single-factorial ANOVA. Inferior and temporal RNFL thickness significantly differed between the control and POAG groups. No significant difference was observed in RV among three groups. In the POAG group,.the maximum area under the ROC curve(AROC) of mean RNFL thickness was 0.845. The maximum AROC of optic disk parameters was RA / DA(0.998), followed by CA / DA(0.997). The AROC of CA, RA, CV, and DV were all > 0.900.Conclusion:.OCT may serve as a useful diagnostic modality in distinguishing suspected glaucoma from POAG.展开更多
This paper introduces the fundamental principle and features ofmagneto-optical storage technol- ogy, and discuses the trend and aseries of key techniques for increasing the data storage density ofmagneto-opti- cal dis...This paper introduces the fundamental principle and features ofmagneto-optical storage technol- ogy, and discuses the trend and aseries of key techniques for increasing the data storage density ofmagneto-opti- cal disk. The three ways including MO media, recordingmethod and readout method for increasing the disk ca- pacity havebeen discussed. Moreover, the importance with the exchange-coupledeffect between the magnetic layers and recording domain morphology isemphasized.展开更多
Detection of polystyrene beads with a diameter of 100 nm was conducted using an optical disk drive tester equipped with a laser of 405 nm wavelength and an objective lens with a numerical aperture of 0.65. The polysty...Detection of polystyrene beads with a diameter of 100 nm was conducted using an optical disk drive tester equipped with a laser of 405 nm wavelength and an objective lens with a numerical aperture of 0.65. The polystyrene beads were used to mimic the influenza virus. A grooved disk with a (ZnS)85(SiO2)15/SiO2 layered surface structure was used for the detection. The detection of influenza viruses (A/Udorn/307/1972) with Au nanoparticles was also demonstrated using the optical disk drive tester. In this case, a grooved disk with an indium tin oxide (ITO) film was used. The ITO film functioned both to tune the reflectance of the disk and as an electrically conductive layer for scanning electron microscopy. In both cases, the target substances were successfully recognized in a single scan with a high scanning speed of 4.9 m/s. The results indicate that this optical disk system can be used to detect 100 nm scale substances like influenza viruses, which are smaller than the diffraction limit of the system.展开更多
Purpose: To investigate the difference of stereometric parameters of optic nerve head between the normal subjects and patients with big-cupped disk and primary open angle glaucoma (POAG).Methods: Twenty-two cases (44 ...Purpose: To investigate the difference of stereometric parameters of optic nerve head between the normal subjects and patients with big-cupped disk and primary open angle glaucoma (POAG).Methods: Twenty-two cases (44 eyes) of normal subjects, 17 cases (34 eyes) of patients with big-cupped disk and 19 cases (37 eyes) of patients with POAG underwent Heidelberg Retina Tomograph (HRT) examination to get topography images and stereometric parameters of optic nerve head.Results: The stereometric parameters of optic nerve head of the normal, patients with big-cupped disk and POAG were 1) disk area (mm2): 1. 995± 0. 501, 2. 407±0. 661 and 2. 248±0.498; 2) cup area (mm2): 0.573±0.264, 1. 095±0. 673 and 1. 340±0. 516; 3) cup/disk ratio: 0. 25±0. 095, 0. 428±0. 176 and 0. 589±0.195; 4) rim area (mm2): 1.461±0.328, 1.312±0.418 and 0. 905± 0.409; 5)cup volume (mm3): 0. 108±0. 073, 0. 347±0. 346 and 0. 550 ±0. 394; 6) rim volume (mm3): 0. 421±0. 111, 0. 378±0. 225 and 0. 224±0. 189; 7) mean cup展开更多
Optic disc drusen (ODD) are hyaline deposits in the optic nerve head, occurring in approximately 2% of the population. ODD may be superficial and visible, or buried and either invisible or seen only as elevation of th...Optic disc drusen (ODD) are hyaline deposits in the optic nerve head, occurring in approximately 2% of the population. ODD may be superficial and visible, or buried and either invisible or seen only as elevation of the optic disc, mimicking optic disc edema. Advanced optic nerve imaging, including optical coherence tomography (OCT) can be used to diagnose and characterize ODD with very high resolution. Enhanced depth imaging (EDI-OCT) in particular has emerged as the optimal modality to directly visualize ODD. This modality has led to a greater ability to differentiate ODD from optic disc edema and prevent misdiagnosis or invasive testing. We review the characteristic findings of ODD on OCT, their distinguishing features, and the use of OCT as a biomarker in the neuro-ophthalmic assessment of ODD.展开更多
In the practical magneto opticaldisk productionline,alloysputteringtargetisalwaysusedtosputter recording film , whileinlaid targetisrarely used .In ourlaboratory,a seriesof al loy targets forsputtering magneto- opti...In the practical magneto opticaldisk productionline,alloysputteringtargetisalwaysusedtosputter recording film , whileinlaid targetisrarely used .In ourlaboratory,a seriesof al loy targets forsputtering magneto- optical recording film were prepared and theeffect ofcomposition andsputtering parameterson magneto opticalpropertiesarestudied . Thesputter ing rateof Al,Siand Tb Fe Co( Mo) undertheconditionsof differentsputtering powerandN2 Argasflux weredetermined and baseontheresults,a variablecomposition andthickness of SiNcan beobtained by meansof regulating sputtering power and gasflux, kindsof Mosputtering filmsareobtained under differentsputtering power and gasflux, and Kerrloop lineofthese magneto opticalfilmsare measuredto acquiretheir propertiessuch as Kerrrota tion,then ,theeffectofsputteringtechnology on Kerrrotationisdiscussed .展开更多
A simple method to fabricate one-dimensional(1-D) and two-dimensional(2-D) ordered micro- and nano-scale patterns is developed based on the original masters from optical discs, using nanoimprint technology and soft st...A simple method to fabricate one-dimensional(1-D) and two-dimensional(2-D) ordered micro- and nano-scale patterns is developed based on the original masters from optical discs, using nanoimprint technology and soft stamps. Polydimethylsiloxane(PDMS) was used to replicate the negative image of the 1-D grating pattern on the masters of CD-R, DVD-R and BD-R optical discs, respectively, and then the 1-D pattern on one of the PDMS stamps was transferred to a blank polycarbonate(PC) substrate by nanoimprint. The 2-D ordered patterns were fabricated by the second imprinting using another PDMS stamp. Different 2-D periodic patterns were obtained depending on the PDMS stamps and the angle between the two times of imprints. This method may provide a way for the fabrication of complex 2-D patterns using simple 1-D masters.展开更多
文摘Purpose:.Glaucoma is an eye disease that can lead to irreversible optic nerve damage and cause blindness. Optical coherence tomography.(OCT) allows an early diagnosis of glaucoma by the measurements of the retinal nerve fiber and optic disc parameters.A retrospective study was designed to analyze the effects of the measurement of the retinal nerve fiber layer(RNFL) thickness and the optic disc tomography by spectraldomain OCT on the early diagnosis of suspected glaucoma and primary open angle glaucoma(POAG).Methods:.This was a clinical case-control study. The RNFL thickness around the optic disc and optic disk tomographic parameters of the control(n=51, 98 eyes), suspected glaucoma(n=81,.146 eyes), and POAG groups(n=55, 106 eyes) were measured by OCT. The parameters included superior, inferior, nasal and temporal mean RNFL thickness,.disc area(DA), cup area(CA), rim area(RA), disc volume(DV),cup volume(CV), rim volume(RV), cup / disc area ratio(CA / DA), rim / disc area ratio(RA / DA), cup / disc volume ratio(CV / DV) and rim / disc volume ratio(RV / DV).Results: Superior, nasal, and mean RNFL parameters, DA,CA,RA, DV, CV, CA / DA, RA / DA, CV / DV and RV / DV significantly differed among three groups by single-factorial ANOVA. Inferior and temporal RNFL thickness significantly differed between the control and POAG groups. No significant difference was observed in RV among three groups. In the POAG group,.the maximum area under the ROC curve(AROC) of mean RNFL thickness was 0.845. The maximum AROC of optic disk parameters was RA / DA(0.998), followed by CA / DA(0.997). The AROC of CA, RA, CV, and DV were all > 0.900.Conclusion:.OCT may serve as a useful diagnostic modality in distinguishing suspected glaucoma from POAG.
文摘This paper introduces the fundamental principle and features ofmagneto-optical storage technol- ogy, and discuses the trend and aseries of key techniques for increasing the data storage density ofmagneto-opti- cal disk. The three ways including MO media, recordingmethod and readout method for increasing the disk ca- pacity havebeen discussed. Moreover, the importance with the exchange-coupledeffect between the magnetic layers and recording domain morphology isemphasized.
文摘Detection of polystyrene beads with a diameter of 100 nm was conducted using an optical disk drive tester equipped with a laser of 405 nm wavelength and an objective lens with a numerical aperture of 0.65. The polystyrene beads were used to mimic the influenza virus. A grooved disk with a (ZnS)85(SiO2)15/SiO2 layered surface structure was used for the detection. The detection of influenza viruses (A/Udorn/307/1972) with Au nanoparticles was also demonstrated using the optical disk drive tester. In this case, a grooved disk with an indium tin oxide (ITO) film was used. The ITO film functioned both to tune the reflectance of the disk and as an electrically conductive layer for scanning electron microscopy. In both cases, the target substances were successfully recognized in a single scan with a high scanning speed of 4.9 m/s. The results indicate that this optical disk system can be used to detect 100 nm scale substances like influenza viruses, which are smaller than the diffraction limit of the system.
文摘Purpose: To investigate the difference of stereometric parameters of optic nerve head between the normal subjects and patients with big-cupped disk and primary open angle glaucoma (POAG).Methods: Twenty-two cases (44 eyes) of normal subjects, 17 cases (34 eyes) of patients with big-cupped disk and 19 cases (37 eyes) of patients with POAG underwent Heidelberg Retina Tomograph (HRT) examination to get topography images and stereometric parameters of optic nerve head.Results: The stereometric parameters of optic nerve head of the normal, patients with big-cupped disk and POAG were 1) disk area (mm2): 1. 995± 0. 501, 2. 407±0. 661 and 2. 248±0.498; 2) cup area (mm2): 0.573±0.264, 1. 095±0. 673 and 1. 340±0. 516; 3) cup/disk ratio: 0. 25±0. 095, 0. 428±0. 176 and 0. 589±0.195; 4) rim area (mm2): 1.461±0.328, 1.312±0.418 and 0. 905± 0.409; 5)cup volume (mm3): 0. 108±0. 073, 0. 347±0. 346 and 0. 550 ±0. 394; 6) rim volume (mm3): 0. 421±0. 111, 0. 378±0. 225 and 0. 224±0. 189; 7) mean cup
文摘Optic disc drusen (ODD) are hyaline deposits in the optic nerve head, occurring in approximately 2% of the population. ODD may be superficial and visible, or buried and either invisible or seen only as elevation of the optic disc, mimicking optic disc edema. Advanced optic nerve imaging, including optical coherence tomography (OCT) can be used to diagnose and characterize ODD with very high resolution. Enhanced depth imaging (EDI-OCT) in particular has emerged as the optimal modality to directly visualize ODD. This modality has led to a greater ability to differentiate ODD from optic disc edema and prevent misdiagnosis or invasive testing. We review the characteristic findings of ODD on OCT, their distinguishing features, and the use of OCT as a biomarker in the neuro-ophthalmic assessment of ODD.
文摘In the practical magneto opticaldisk productionline,alloysputteringtargetisalwaysusedtosputter recording film , whileinlaid targetisrarely used .In ourlaboratory,a seriesof al loy targets forsputtering magneto- optical recording film were prepared and theeffect ofcomposition andsputtering parameterson magneto opticalpropertiesarestudied . Thesputter ing rateof Al,Siand Tb Fe Co( Mo) undertheconditionsof differentsputtering powerandN2 Argasflux weredetermined and baseontheresults,a variablecomposition andthickness of SiNcan beobtained by meansof regulating sputtering power and gasflux, kindsof Mosputtering filmsareobtained under differentsputtering power and gasflux, and Kerrloop lineofthese magneto opticalfilmsare measuredto acquiretheir propertiessuch as Kerrrota tion,then ,theeffectofsputteringtechnology on Kerrrotationisdiscussed .
基金supported by the National Natural Science Foundation of China(Nos.11504259,21575098 and 21505098)the Shanxi International Cooperation Project(No.2015081019)+2 种基金the Shanxi Scholarship Council(No.2013-038)the Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi(No.2015123)the Scientific Research Starting Foundation from Taiyuan University of Technology(No.tyut-rc201162a)
文摘A simple method to fabricate one-dimensional(1-D) and two-dimensional(2-D) ordered micro- and nano-scale patterns is developed based on the original masters from optical discs, using nanoimprint technology and soft stamps. Polydimethylsiloxane(PDMS) was used to replicate the negative image of the 1-D grating pattern on the masters of CD-R, DVD-R and BD-R optical discs, respectively, and then the 1-D pattern on one of the PDMS stamps was transferred to a blank polycarbonate(PC) substrate by nanoimprint. The 2-D ordered patterns were fabricated by the second imprinting using another PDMS stamp. Different 2-D periodic patterns were obtained depending on the PDMS stamps and the angle between the two times of imprints. This method may provide a way for the fabrication of complex 2-D patterns using simple 1-D masters.
