Objective:To systematically evaluate the effect of marine Omega-3 polyunsaturated fatty acids(Omega-3 PUFA)on adiponectin and leptin levels in overweight and obese patients.Methods:The computer searched PubMed,Embase,...Objective:To systematically evaluate the effect of marine Omega-3 polyunsaturated fatty acids(Omega-3 PUFA)on adiponectin and leptin levels in overweight and obese patients.Methods:The computer searched PubMed,Embase,Cochrane Library and CNKI electronic databases for randomized controlled experiments on the levels of marine Omega-3 PUFA and adiponectin and leptin in overweight and obese patients.The two researchers independently screened,evaluated and included the literatures and extracted the data.Meta analysis was carried out with Revman 5.3 software.Results:A total of 8 articles and 607 subjects were included.The results showed that Omega-3 PUFA from marine sources did not increase in adiponectin levels[SMD=0.32,95%CI=(-0.13,0.76)],while there was no significant did not reduce the leptin level of patients[SMD=-0.22,95%CI=(-0.53,0.09)].Conclusion:Marinederived Omega-3 PUFA can improve circulating leptin and adiponectin levels in overweight and obese patients,increase serum adiponectin levels and reduce leptin levels,but the difference is not obvious.Further research is still needed to determine the effect of Omega-3 PUFA on Adipokine in overweight and obese people.展开更多
文摘目的建立近红外光谱法(near-infrared spectrometry,NIRS)快速检测鸡蛋中Omega-3多不饱和脂肪酸含量。方法共采集115份市售鸡蛋,将其蛋黄冻干处理后制成蛋黄粉,采用气相色谱法测得α-亚麻酸(α-linolenic acid,ALA)、二十碳五烯酸(eicosapentaenoic acid,EPA)和二十二碳六烯酸(docosahexaenoic acid,DHA)的含量,并用近红外光谱仪进行光谱扫描。基于偏最小二乘法(partial least-square method,PLS)用20种方法对光谱图进行预处理,建立ALA、EPA和DHA的近红外定量检测模型,以校正集决定系数(coefficient of determination of calibration set,rc)、验证集决定系数(coefficient of determination of prediction set,rp)和相对分析误差(relative percent deviation,RPD)作为模型的评价指标。结果ALA、EPA和DHA最优的光谱预处理方法分别为多元散射校正(multiple scatter correction,MSC)+二阶求导(second derivative,2nd)+Savitzky-Golay平滑、2nd和标准正态变化(standard normal variate,SNV)+2nd+Norris Derivative平滑,模型的rc值分别为0.9906、0.9311和0.9058,rp值分别为0.9894、0.6978和0.9098。结论该研究成功建立可用于鸡蛋中ALA、EPA和DHA含量快速测定的近红外模型,为鸡蛋中脂肪酸得快速检测提供了一种有效工具。
基金National natural science foundation of China(No.81673970,81874449)。
文摘Objective:To systematically evaluate the effect of marine Omega-3 polyunsaturated fatty acids(Omega-3 PUFA)on adiponectin and leptin levels in overweight and obese patients.Methods:The computer searched PubMed,Embase,Cochrane Library and CNKI electronic databases for randomized controlled experiments on the levels of marine Omega-3 PUFA and adiponectin and leptin in overweight and obese patients.The two researchers independently screened,evaluated and included the literatures and extracted the data.Meta analysis was carried out with Revman 5.3 software.Results:A total of 8 articles and 607 subjects were included.The results showed that Omega-3 PUFA from marine sources did not increase in adiponectin levels[SMD=0.32,95%CI=(-0.13,0.76)],while there was no significant did not reduce the leptin level of patients[SMD=-0.22,95%CI=(-0.53,0.09)].Conclusion:Marinederived Omega-3 PUFA can improve circulating leptin and adiponectin levels in overweight and obese patients,increase serum adiponectin levels and reduce leptin levels,but the difference is not obvious.Further research is still needed to determine the effect of Omega-3 PUFA on Adipokine in overweight and obese people.
