目的评价Oculyzer眼前节分析仪引导的个体化准分子激光原位角膜磨镶术（laser in situ keratomileusis，LASIK）治疗角膜准分子激光术后不规则散光的临床疗效。方法选取2009年5月至2011年5月于我院就诊的患者7例（9眼），均有准分子激...目的评价Oculyzer眼前节分析仪引导的个体化准分子激光原位角膜磨镶术（laser in situ keratomileusis，LASIK）治疗角膜准分子激光术后不规则散光的临床疗效。方法选取2009年5月至2011年5月于我院就诊的患者7例（9眼），均有准分子激光手术史，均存在不同程度的偏中心和不规则散光，均行Oculyzer引导的个体化LASIK治疗，比较手术前后裸眼视力（un—correctedvisualacuity，UCVA）、最佳矫正视力（best corrected visual acuity，BCVA）、散光度、角膜表面变异指数、角膜高度的非对称指数等指标。结果所有患者术后UCVA较术前均有明显提高，术前为0．2～0．6，术后3个月为0．8～1．0；BCVA术前同UCVA，术后3个月为1．0～1．2；手术前后差异均有统计学意义（均为P〈0．05）。术前散光度为（-2．14±3．56）D，术后3个月为（-0．394-0．78）D，术后6个月为（-0．26±0．53）D，手术前后差异均有统计学意义（均为P〈0．05）。术后角膜表面变异指数与角膜高度的非对称指数均较术前下降，差异均有统计学意义（均为P〈0．05）。结论Oculyzer眼前节分析仪引导的个体化LASIK治疗角膜准分子激光术后不规则散光疗效确切，安全性高。展开更多
AIM： To evaluate and compare the uniformity of angle Kappa adjustment between Oculyzer and Topolyzer Vario topography guided ablation of laser in situ keratomileusis（LASIK） by EX500 excimer laser for myopia.METHODS...AIM： To evaluate and compare the uniformity of angle Kappa adjustment between Oculyzer and Topolyzer Vario topography guided ablation of laser in situ keratomileusis（LASIK） by EX500 excimer laser for myopia.METHODS： Totally 145 cases（290 consecutive eyes）with myopia received LASIK with a target of emmetropia. The ablation for 86 cases（172 eyes） was guided manually based on Oculyzer topography（study group）, while the ablation for 59 cases（118 eyes） was guided automatically by Topolyzer Vario topography（control group）. Measurement of adjustment values included data respectively in horizontal and vertical direction of cornea. RESULTS： Horizontally, synclastic adjustment between manually actual values（dx_（manu）） and Oculyzer topography guided data（dx_（ocu）） accounts 35.5% in study group, with mean dx_（manu）/dx_（ocu） of 0.78±0.48; while in control group, synclastic adjustment between automatically actual values（dx_（auto）） and Oculyzer topography data（dx_（ocu）） accounts 54.2%, with mean dx_（auto）/dx_（ocu） of 0.79±0.66. Vertically, synclastic adjustment between dy_（manu） and dy_（ocu） accounts 55.2% in study group, with mean dy_（manu）/dy_（ocu） of 0.61±0.42; while in control group, synclastic adjustment between dy_（auto） and dy_（ocu） accounts 66.1%, with mean dy_（auto）/dy_（ocu） of 0.66±0.65. There was no statistically significant difference in ratio of actual values/Oculyzer topography guided data in horizontal and vertical direction between two groups（P=0.951, 0.621）.CONCLUSION： There is high consistency in angle Kappa adjustment guided manually by Oculyzer and guided automatically by Topolyzer Vario topography during corneal refractive surgery by Wave Light EX500 excimer laser.展开更多
基金Supported by 215 High Level Talent Fund of Beijing Health Government(No.2013-2-023)
文摘AIM： To evaluate and compare the uniformity of angle Kappa adjustment between Oculyzer and Topolyzer Vario topography guided ablation of laser in situ keratomileusis（LASIK） by EX500 excimer laser for myopia.METHODS： Totally 145 cases（290 consecutive eyes）with myopia received LASIK with a target of emmetropia. The ablation for 86 cases（172 eyes） was guided manually based on Oculyzer topography（study group）, while the ablation for 59 cases（118 eyes） was guided automatically by Topolyzer Vario topography（control group）. Measurement of adjustment values included data respectively in horizontal and vertical direction of cornea. RESULTS： Horizontally, synclastic adjustment between manually actual values（dx_（manu）） and Oculyzer topography guided data（dx_（ocu）） accounts 35.5% in study group, with mean dx_（manu）/dx_（ocu） of 0.78±0.48; while in control group, synclastic adjustment between automatically actual values（dx_（auto）） and Oculyzer topography data（dx_（ocu）） accounts 54.2%, with mean dx_（auto）/dx_（ocu） of 0.79±0.66. Vertically, synclastic adjustment between dy_（manu） and dy_（ocu） accounts 55.2% in study group, with mean dy_（manu）/dy_（ocu） of 0.61±0.42; while in control group, synclastic adjustment between dy_（auto） and dy_（ocu） accounts 66.1%, with mean dy_（auto）/dy_（ocu） of 0.66±0.65. There was no statistically significant difference in ratio of actual values/Oculyzer topography guided data in horizontal and vertical direction between two groups（P=0.951, 0.621）.CONCLUSION： There is high consistency in angle Kappa adjustment guided manually by Oculyzer and guided automatically by Topolyzer Vario topography during corneal refractive surgery by Wave Light EX500 excimer laser.
