Objective:To explore the value of cyclosporin eye drops in treating dry eye after cataract surgery.Methods:A total of 150 patients with dry eye after cataract surgery were randomly divided into group A(n=50),group B(n...Objective:To explore the value of cyclosporin eye drops in treating dry eye after cataract surgery.Methods:A total of 150 patients with dry eye after cataract surgery were randomly divided into group A(n=50),group B(n=50),and group C(n=50).Artificial tears combined with cyclosporin eye drops were used in group A,artificial tears were used in group B,and no dry eye medication was used in group C.The clinical efficacy,ocular surface function and tear inflammatory factor level before and after surgery were compared between the groups.Results:The total effective rate of group A was 96.00%,which was significantly higher than that of group B and group C(p<.05);three months after surgery,the levels of cornealfluorescein staining score(FL score),tear meniscus height(TMH)and tear inflammatory factors[interleukin 6(IL-6),interleukin 8(IL-8),tumor necrosis factorα(TNF-α)]in group A were lower than those in group B,and those indicators in group B were lower than those in group C,and the difference between the two groups was statistically significant(p<.05);three months after surgery,Schirmer test(SIT)and break-up time(BUT)in group A were higher than those in group B,and those indicators in group B were higher than those in group C,and the difference between the two groups was statistically significant(p<.05).Conclusions:The effect of cyclosporin eye drops in treating dry eye after cataract surgery is satisfactory,significantly improving the ocular surface function and reducing the level of tear inflammatory factors,which is worthy of promotion.展开更多
文摘Objective:To explore the value of cyclosporin eye drops in treating dry eye after cataract surgery.Methods:A total of 150 patients with dry eye after cataract surgery were randomly divided into group A(n=50),group B(n=50),and group C(n=50).Artificial tears combined with cyclosporin eye drops were used in group A,artificial tears were used in group B,and no dry eye medication was used in group C.The clinical efficacy,ocular surface function and tear inflammatory factor level before and after surgery were compared between the groups.Results:The total effective rate of group A was 96.00%,which was significantly higher than that of group B and group C(p<.05);three months after surgery,the levels of cornealfluorescein staining score(FL score),tear meniscus height(TMH)and tear inflammatory factors[interleukin 6(IL-6),interleukin 8(IL-8),tumor necrosis factorα(TNF-α)]in group A were lower than those in group B,and those indicators in group B were lower than those in group C,and the difference between the two groups was statistically significant(p<.05);three months after surgery,Schirmer test(SIT)and break-up time(BUT)in group A were higher than those in group B,and those indicators in group B were higher than those in group C,and the difference between the two groups was statistically significant(p<.05).Conclusions:The effect of cyclosporin eye drops in treating dry eye after cataract surgery is satisfactory,significantly improving the ocular surface function and reducing the level of tear inflammatory factors,which is worthy of promotion.
