1 Introduction Precipitation and enrichment of gold is an important subject in the study of gold deposits.As the most common sulphide in gold deposits,pyrite is not only a good indicator of the evolution of mineralizi...1 Introduction Precipitation and enrichment of gold is an important subject in the study of gold deposits.As the most common sulphide in gold deposits,pyrite is not only a good indicator of the evolution of mineralizing fluids,but also the important gold-bearing mineral.In this paper,展开更多
Alkaline lacustrine shale is highly heterogeneous,and the complex relationship between the organicinorganic porosity network and hydrocarbon occurrence restricts the effectiveness of shale oil exploration and developm...Alkaline lacustrine shale is highly heterogeneous,and the complex relationship between the organicinorganic porosity network and hydrocarbon occurrence restricts the effectiveness of shale oil exploration and development.Herein,we investigated the Fengcheng Formation(P_(1)f)in Mahu Sag.This study integrated geochemistry,Soxhlet extraction,scanning electron microscopy,gas adsorption,and nuclear magnetic resonance T_(1)-T_(2)spectroscopy to elucidate the microscopic oil occurrence mechanisms in shales.Results indicate the presence of felsic shale,dolomitic shale,lime shale,and mixed shale within the P_(1)f.Matrix pores and microfractures associated with inorganic minerals are the predominant pore types in P_(1)f.Adsorbed oil primarily resides on the surfaces of organic matter and clay minerals,while free oil predominantly occupies inorganic pores and microfractures with larger pore sizes.Variations exist in the quantity and distribution of shale oil accumulation across different scales,where free oil and adsorbed oil are governed by dominant pores with diameters exceeding 10 nm and ineffective pores with diameters below 10 nm,respectively.Shale oil occurrence characteristics are influenced by organic matter,pore structure,and mineral composition.Felsic shale exhibits a high abundance of dominant pores,possesses the highest oil content,predominantly harbors free oil within these dominant pores,and demonstrates good mobility.Fluid occurrence in dolomitic shale and lime shale is intricate,with low oil content and a free oil to adsorbed oil ratio of 1:1.Mixed shale exhibits elevated clay mineral content and a scarcity of dominant pores.Moreover,ineffective pores contain increased bound water,resulting in medium oil content and limited mobility predominantly due to adsorption.Presently,shale oil mainly occurs in the dominant pores with a diameter larger than 10 nm in a free state.During the exploration and development of alkaline lacustrine shale oil resources,emphasis should be placed on identifying sweet spots within the felsic shale characterized by dominant pores.展开更多
ObjectiveThis study aims to characterize the occurrences and interior structural features of botryoidal structures from the Sinian Dengying Formation in the Sichuan Basin of Southwestern China, and to shed light on th...ObjectiveThis study aims to characterize the occurrences and interior structural features of botryoidal structures from the Sinian Dengying Formation in the Sichuan Basin of Southwestern China, and to shed light on their formation mechanism.展开更多
The moisture occurrence in coal reservoirs has important significance in the evaluation of gas-bearing properties and production of coalbed methane(CBM).In order to investigate the occurrence mechanism of moisture con...The moisture occurrence in coal reservoirs has important significance in the evaluation of gas-bearing properties and production of coalbed methane(CBM).In order to investigate the occurrence mechanism of moisture content of coals,a series of experiments including mercury intrusion porosimetry(MIP),low temperature nitrogen gas absorption/desorption(N_(2)GA)and nuclear magnetic resonance(NMR)are conducted in this study to characterize and quantify pore structure properties.The nature of occurrence of moisture content in coal reservoir pores is then divided into four categories by NMR saturation and centrifugation experiments.The bound water content in the adsorption pore accounts for the highest proportion.Based on the relevance of bound water content and its influencing factors,moisture occurrence in coal reservoirs of different ranks is revealed by SPSS statistical methods.The moisture content of low-rank coal is mainly controlled by elemental oxygen and specific surface area,whereas for medium-and high-rank coals,this is controlled mainly by minerals.Our study finds application in CBM evaluation and development.展开更多
Diabetes is a chronic disease recognized by the World Health Organization,which is harmful to human life and health.With the improvement of people's quality of life,people's diet structure has changed greatly,...Diabetes is a chronic disease recognized by the World Health Organization,which is harmful to human life and health.With the improvement of people's quality of life,people's diet structure has changed greatly,and the primary"three high"prevalence rate has risen sharply.The main reason for the impaired life expectancy of a large number of diabetic patients is the threat of a series of cardiovascular complications.According to statistics,the risk of cardiovascular disease in diabetic patients are 2-4 times higher than that in non-diabetic patients.More than 80% of patients with type 2 diabetes die of cardiovascular disease every year,and 75% of them have ischemic heart disease[1].All kinds of data show that diabetes mellitus complicated with cardiovascular diseases have become a worldwide public health problem.We must try our best to find a cure mechanism and give patients a healthy life.In order to effectively curb the threat of diabetes complicated with cardiovascular disease patients,we should strengthen the research in this field.Through the analysis of the risk factors of diabetic cardiovascular disease,we can let the majority of medical workers understand the superficial and potential risk factors,to formulate scientific and reasonable treatment plan,for further improving the quality of life of patients.In the following,the author first introduces the basic situation of diabetes and cardiovascular complications,then introduces the main risk factors of diabetic cardiovascular disease one by one,hoping that this study can help to improve the cure rate of diabetes complicated with cardiovascular disease.展开更多
Postoperative adhesion(POA)widely occurs in soft tissues and usually leads to chronic pain,dysfunction of adjacent organs and some acute complications,seriously reducing patients’quality of life and even being life-t...Postoperative adhesion(POA)widely occurs in soft tissues and usually leads to chronic pain,dysfunction of adjacent organs and some acute complications,seriously reducing patients’quality of life and even being life-threatening.Except for adhesiolysis,there are few effective methods to release existing adhesion.However,it requires a second operation and inpatient care and usually triggers recurrent adhesion in a great incidence.Hence,preventing POA formation has been regarded as the most effective clinical strategy.Biomaterials have attracted great attention in preventing POA because they can act as both barriers and drug carriers.Nevertheless,even though much reported research has been demonstrated their efficacy on POA inhibition to a certain extent,thoroughly preventing POA formation is still challenging.Meanwhile,most biomaterials for POA prevention were designed based on limited experiences,not a solid theoretical basis,showing blindness.Hence,we aimed to provide guidance for designing anti-adhesion materials applied in different soft tissues based on the mechanisms of POA occurrence and development.We first classified the postoperative adhesions into four categories according to the different components of diverse adhesion tissues,and named them as“membranous adhesion”,“vascular adhesion”,“adhesive adhesion”and“scarred adhesion”,respectively.Then,the process of the occurrence and development of POA were analyzed,and the main influencing factors in different stages were clarified.Further,we proposed seven strategies for POA prevention by using biomaterials according to these influencing factors.Meanwhile,the relevant practices were summarized according to the corresponding strategies and the future perspectives were analyzed.展开更多
A possible mechanism is put forward in this paper for El Nino events from the viewpoint of plate tec- tonics and oceanic geology.A number of the data are cited to illustrate the views that sea-bottom volcanic ac- tivi...A possible mechanism is put forward in this paper for El Nino events from the viewpoint of plate tec- tonics and oceanic geology.A number of the data are cited to illustrate the views that sea-bottom volcanic ac- tivities and hot springs may cause El Nino events.展开更多
"Boundarics in Biomedicine"is a cutting-edge interdisciplinary discipline,which is of great significance for understanding the origin of life,the interaction between internal and external environments,and th..."Boundarics in Biomedicine"is a cutting-edge interdisciplinary discipline,which is of great significance for understanding the origin of life,the interaction between internal and external environments,and the mechanism of disease occurrence and evolution.Here,the definition of Boundarics in Biomedicine is first described,including its connotation,research object,research method,challenges,and future perspectives."Boundarics in Biomedicine"is a cutting-edge interdisciplinary discipline involving multiple fields(e.g.,bioscience,medicine,chemistry,materials science,and information science)dedicated to investigating and solving key scientific questions in the formation,identification,and evolution of living organism boundaries.Specifically,it encompasses 3 levels:(a)the boundary between the living organism and the external environment,(b)internal boundary within living organism,and(c)the boundary related to disease in living organism.The advancement of research in Boundarics in Biomedicine is of great scientific significance for understanding the origin of life,the interaction between internal and external environments,and the mechanism of disease occurrence and evolution,thus providing novel principles,technologies,and methods for early diagnosis and prevention of major diseases,personalized drug development,and prognosis assessment(Fig.1).展开更多
基金granted by the National Natural Science Foundation of China (Grant no. 41272055)
文摘1 Introduction Precipitation and enrichment of gold is an important subject in the study of gold deposits.As the most common sulphide in gold deposits,pyrite is not only a good indicator of the evolution of mineralizing fluids,but also the important gold-bearing mineral.In this paper,
基金financially supported by the State Key Laboratory of Shale Oil and Gas Enrichment Mechanisms and Efficient Development(33550000-22-ZC0613-0006)National Natural Science Foundation of China(42202133)+2 种基金CNPC Innovation Fund(2022DQ02-0106)Strategic Cooperation Technology Projects of the CNPC and CUPB(ZLZX2020-01-05)Key Laboratory of Tectonics and Petroleum Resources(China University of Geosciences),Ministry of Education,China(TPR-2023-05)。
文摘Alkaline lacustrine shale is highly heterogeneous,and the complex relationship between the organicinorganic porosity network and hydrocarbon occurrence restricts the effectiveness of shale oil exploration and development.Herein,we investigated the Fengcheng Formation(P_(1)f)in Mahu Sag.This study integrated geochemistry,Soxhlet extraction,scanning electron microscopy,gas adsorption,and nuclear magnetic resonance T_(1)-T_(2)spectroscopy to elucidate the microscopic oil occurrence mechanisms in shales.Results indicate the presence of felsic shale,dolomitic shale,lime shale,and mixed shale within the P_(1)f.Matrix pores and microfractures associated with inorganic minerals are the predominant pore types in P_(1)f.Adsorbed oil primarily resides on the surfaces of organic matter and clay minerals,while free oil predominantly occupies inorganic pores and microfractures with larger pore sizes.Variations exist in the quantity and distribution of shale oil accumulation across different scales,where free oil and adsorbed oil are governed by dominant pores with diameters exceeding 10 nm and ineffective pores with diameters below 10 nm,respectively.Shale oil occurrence characteristics are influenced by organic matter,pore structure,and mineral composition.Felsic shale exhibits a high abundance of dominant pores,possesses the highest oil content,predominantly harbors free oil within these dominant pores,and demonstrates good mobility.Fluid occurrence in dolomitic shale and lime shale is intricate,with low oil content and a free oil to adsorbed oil ratio of 1:1.Mixed shale exhibits elevated clay mineral content and a scarcity of dominant pores.Moreover,ineffective pores contain increased bound water,resulting in medium oil content and limited mobility predominantly due to adsorption.Presently,shale oil mainly occurs in the dominant pores with a diameter larger than 10 nm in a free state.During the exploration and development of alkaline lacustrine shale oil resources,emphasis should be placed on identifying sweet spots within the felsic shale characterized by dominant pores.
基金supported by the National Natural Science Foundation of China(Grant No.41402126)
文摘ObjectiveThis study aims to characterize the occurrences and interior structural features of botryoidal structures from the Sinian Dengying Formation in the Sichuan Basin of Southwestern China, and to shed light on their formation mechanism.
基金the National Major Science and Technology Project(grant no.2017ZX05064)Major Special Projects of PetroChina(grant no.2017E-1404).
文摘The moisture occurrence in coal reservoirs has important significance in the evaluation of gas-bearing properties and production of coalbed methane(CBM).In order to investigate the occurrence mechanism of moisture content of coals,a series of experiments including mercury intrusion porosimetry(MIP),low temperature nitrogen gas absorption/desorption(N_(2)GA)and nuclear magnetic resonance(NMR)are conducted in this study to characterize and quantify pore structure properties.The nature of occurrence of moisture content in coal reservoir pores is then divided into four categories by NMR saturation and centrifugation experiments.The bound water content in the adsorption pore accounts for the highest proportion.Based on the relevance of bound water content and its influencing factors,moisture occurrence in coal reservoirs of different ranks is revealed by SPSS statistical methods.The moisture content of low-rank coal is mainly controlled by elemental oxygen and specific surface area,whereas for medium-and high-rank coals,this is controlled mainly by minerals.Our study finds application in CBM evaluation and development.
文摘Diabetes is a chronic disease recognized by the World Health Organization,which is harmful to human life and health.With the improvement of people's quality of life,people's diet structure has changed greatly,and the primary"three high"prevalence rate has risen sharply.The main reason for the impaired life expectancy of a large number of diabetic patients is the threat of a series of cardiovascular complications.According to statistics,the risk of cardiovascular disease in diabetic patients are 2-4 times higher than that in non-diabetic patients.More than 80% of patients with type 2 diabetes die of cardiovascular disease every year,and 75% of them have ischemic heart disease[1].All kinds of data show that diabetes mellitus complicated with cardiovascular diseases have become a worldwide public health problem.We must try our best to find a cure mechanism and give patients a healthy life.In order to effectively curb the threat of diabetes complicated with cardiovascular disease patients,we should strengthen the research in this field.Through the analysis of the risk factors of diabetic cardiovascular disease,we can let the majority of medical workers understand the superficial and potential risk factors,to formulate scientific and reasonable treatment plan,for further improving the quality of life of patients.In the following,the author first introduces the basic situation of diabetes and cardiovascular complications,then introduces the main risk factors of diabetic cardiovascular disease one by one,hoping that this study can help to improve the cure rate of diabetes complicated with cardiovascular disease.
基金financial support from the National Natural Science Foundation of China(Nos.32171345,T2288101,U20A20390,and 11827803)Fok Ying Tung Education Foundation(No.141039)+1 种基金International Joint Research Center of Aerospace Biotechnology and Medical Engineering,Ministry of Science and Technology of China,the 111 Project(No.B13003)the Academic Excellence Foundation of BUAA for PhD Students.
文摘Postoperative adhesion(POA)widely occurs in soft tissues and usually leads to chronic pain,dysfunction of adjacent organs and some acute complications,seriously reducing patients’quality of life and even being life-threatening.Except for adhesiolysis,there are few effective methods to release existing adhesion.However,it requires a second operation and inpatient care and usually triggers recurrent adhesion in a great incidence.Hence,preventing POA formation has been regarded as the most effective clinical strategy.Biomaterials have attracted great attention in preventing POA because they can act as both barriers and drug carriers.Nevertheless,even though much reported research has been demonstrated their efficacy on POA inhibition to a certain extent,thoroughly preventing POA formation is still challenging.Meanwhile,most biomaterials for POA prevention were designed based on limited experiences,not a solid theoretical basis,showing blindness.Hence,we aimed to provide guidance for designing anti-adhesion materials applied in different soft tissues based on the mechanisms of POA occurrence and development.We first classified the postoperative adhesions into four categories according to the different components of diverse adhesion tissues,and named them as“membranous adhesion”,“vascular adhesion”,“adhesive adhesion”and“scarred adhesion”,respectively.Then,the process of the occurrence and development of POA were analyzed,and the main influencing factors in different stages were clarified.Further,we proposed seven strategies for POA prevention by using biomaterials according to these influencing factors.Meanwhile,the relevant practices were summarized according to the corresponding strategies and the future perspectives were analyzed.
文摘A possible mechanism is put forward in this paper for El Nino events from the viewpoint of plate tec- tonics and oceanic geology.A number of the data are cited to illustrate the views that sea-bottom volcanic ac- tivities and hot springs may cause El Nino events.
基金supported by the National Natural Science Foundation of China(grant nos.T2342011,32025021,and T2222021).
文摘"Boundarics in Biomedicine"is a cutting-edge interdisciplinary discipline,which is of great significance for understanding the origin of life,the interaction between internal and external environments,and the mechanism of disease occurrence and evolution.Here,the definition of Boundarics in Biomedicine is first described,including its connotation,research object,research method,challenges,and future perspectives."Boundarics in Biomedicine"is a cutting-edge interdisciplinary discipline involving multiple fields(e.g.,bioscience,medicine,chemistry,materials science,and information science)dedicated to investigating and solving key scientific questions in the formation,identification,and evolution of living organism boundaries.Specifically,it encompasses 3 levels:(a)the boundary between the living organism and the external environment,(b)internal boundary within living organism,and(c)the boundary related to disease in living organism.The advancement of research in Boundarics in Biomedicine is of great scientific significance for understanding the origin of life,the interaction between internal and external environments,and the mechanism of disease occurrence and evolution,thus providing novel principles,technologies,and methods for early diagnosis and prevention of major diseases,personalized drug development,and prognosis assessment(Fig.1).