The impact of longitudinal stiffener configurations on the structural performance of orthotropic steel bridge decks(OSD)was systematically investigated,with emphasis on U-shaped,T-shaped,and rectangular ribs.Finite el...The impact of longitudinal stiffener configurations on the structural performance of orthotropic steel bridge decks(OSD)was systematically investigated,with emphasis on U-shaped,T-shaped,and rectangular ribs.Finite element analysis was employed to evaluate deformation and stress distribution under three critical loading scenarios:vertical uniformload,vertical eccentric load,and lateral uniformload.Equivalentmodels ensuring identical steel usage,moment of inertia,and centroid alignment were established to compare five stiffener configurations.Results demonstrate that U-rib configurations exhibit superior performance in controlling local displacements and minimizing stress concentrations.Under eccentric loading,U-ribs significantly reduce deck displacement andmitigate stress fluctuations at critical junctions compared to alternative stiffeners.Stability analysis further reveals that U-ribs achieve stability coefficients substantially higher than open-section alternatives,particularly excelling under lateral loading due to enhanced torsional rigidity.Parametric optimization identifies key geometric thresholds where U-rib thickness exceeding 6 mm yields diminishing returns in stress reduction and stability enhancement,while deck flange thickness beyond 16 mm provides marginal improvements in displacement control despite increased material usage.An optimized design combining 6-mm U-ribs with 16-mm deck flanges is proposed,balancing structural efficiency with stringent deformation requirements for high-speed rail bridges.These findings provide foundational insights for optimizing stiffener selection and enhancing the longevity of orthotropic steel bridge decks in heavy-load applications.展开更多
Ocular surface disease(OSD)can have a severe impact on patients as it can lead to visual impairment and persistent discomfort.Ocular surface reconstruction(OSR)is an approach to the management of ocular diseases that ...Ocular surface disease(OSD)can have a severe impact on patients as it can lead to visual impairment and persistent discomfort.Ocular surface reconstruction(OSR)is an approach to the management of ocular diseases that cause structural damage to the ocular surface.OSR encompasses both medical and surgical treatment options.In this review,we discuss the medical and surgical strategies used in OSR.Medical management often aims to treat tear insufficiency,inflammation,and keratinization.Surgical treatments may be employed for a variety of reasons,including failure of medical management.This may include improving the oculo-palpebral structures in order to improve lid positioning and tear film.Additional therapies focus on improving tear production,such as through salivary gland transplantation.In situations where the ocular surface is so severely damaged that there is loss of limbal stem cells,limbal stem cell transplant(LSCT)may be indicated.Other surgeries such as amniotic membrane transplant(AMT)and conjunctival flaps(CFs)can help promote corneal healing.Finally,in severe situations where the cornea is beyond salvage,corneal transplantation,such as a penetrating keratoplasty(PKP),can be considered.OSR often requires a combination of medical and surgical approaches targeted to each specific patient’s presentation in order to achieve optimal outcomes.展开更多
Ocular surface disease(OSD)encompasses a diverse range of disorders that impact the ocular tear film and integrity of the ocular surface including the cornea,conjunctiva,lacrimal glands,tear film and eyelids.As the ma...Ocular surface disease(OSD)encompasses a diverse range of disorders that impact the ocular tear film and integrity of the ocular surface including the cornea,conjunctiva,lacrimal glands,tear film and eyelids.As the main functions of the ocular surface are to maintain corneal transparency and hydration and protection of the corneal and conjunctival epithelium,the loss of ocular homeostasis leads to serious clinical manifestations.展开更多
基金supported by the Chongqing Municipal Talent Plan Project(cstc2024ycjh-bgzxm0186).
文摘The impact of longitudinal stiffener configurations on the structural performance of orthotropic steel bridge decks(OSD)was systematically investigated,with emphasis on U-shaped,T-shaped,and rectangular ribs.Finite element analysis was employed to evaluate deformation and stress distribution under three critical loading scenarios:vertical uniformload,vertical eccentric load,and lateral uniformload.Equivalentmodels ensuring identical steel usage,moment of inertia,and centroid alignment were established to compare five stiffener configurations.Results demonstrate that U-rib configurations exhibit superior performance in controlling local displacements and minimizing stress concentrations.Under eccentric loading,U-ribs significantly reduce deck displacement andmitigate stress fluctuations at critical junctions compared to alternative stiffeners.Stability analysis further reveals that U-ribs achieve stability coefficients substantially higher than open-section alternatives,particularly excelling under lateral loading due to enhanced torsional rigidity.Parametric optimization identifies key geometric thresholds where U-rib thickness exceeding 6 mm yields diminishing returns in stress reduction and stability enhancement,while deck flange thickness beyond 16 mm provides marginal improvements in displacement control despite increased material usage.An optimized design combining 6-mm U-ribs with 16-mm deck flanges is proposed,balancing structural efficiency with stringent deformation requirements for high-speed rail bridges.These findings provide foundational insights for optimizing stiffener selection and enhancing the longevity of orthotropic steel bridge decks in heavy-load applications.
文摘Ocular surface disease(OSD)can have a severe impact on patients as it can lead to visual impairment and persistent discomfort.Ocular surface reconstruction(OSR)is an approach to the management of ocular diseases that cause structural damage to the ocular surface.OSR encompasses both medical and surgical treatment options.In this review,we discuss the medical and surgical strategies used in OSR.Medical management often aims to treat tear insufficiency,inflammation,and keratinization.Surgical treatments may be employed for a variety of reasons,including failure of medical management.This may include improving the oculo-palpebral structures in order to improve lid positioning and tear film.Additional therapies focus on improving tear production,such as through salivary gland transplantation.In situations where the ocular surface is so severely damaged that there is loss of limbal stem cells,limbal stem cell transplant(LSCT)may be indicated.Other surgeries such as amniotic membrane transplant(AMT)and conjunctival flaps(CFs)can help promote corneal healing.Finally,in severe situations where the cornea is beyond salvage,corneal transplantation,such as a penetrating keratoplasty(PKP),can be considered.OSR often requires a combination of medical and surgical approaches targeted to each specific patient’s presentation in order to achieve optimal outcomes.
文摘Ocular surface disease(OSD)encompasses a diverse range of disorders that impact the ocular tear film and integrity of the ocular surface including the cornea,conjunctiva,lacrimal glands,tear film and eyelids.As the main functions of the ocular surface are to maintain corneal transparency and hydration and protection of the corneal and conjunctival epithelium,the loss of ocular homeostasis leads to serious clinical manifestations.
