perfluoroalkyl iodides reacted with alkenes in acetonitrile solu- tion containing catalytic amount of organophosphine under mild condition to give the corresponding adducts in moderate to good yields.Reaction was show...perfluoroalkyl iodides reacted with alkenes in acetonitrile solu- tion containing catalytic amount of organophosphine under mild condition to give the corresponding adducts in moderate to good yields.Reaction was shown to involve a free radical mechanism.展开更多
Skeletal editing of organophosphines is highly challenging owing to the high P-C bond dissociation energy.Herein,we report an efficient catalyst-and additive-free skeletal editing strategy to transform easily accessib...Skeletal editing of organophosphines is highly challenging owing to the high P-C bond dissociation energy.Herein,we report an efficient catalyst-and additive-free skeletal editing strategy to transform easily accessible ortho-chalcone based organophosphines into new and complex phosphine oxides,that are unattainable by conventional methods.Water is indispensable to this transformation and serves as the oxygen source to cleave P-C bonds.Interestingly,it is possible to achieve the peripheral modification of organophosphines into phosphonium salts in the absence of water.This water-controlled skeletal editing or peripheral modification strategy is embedded with the merits of high bond-and ring-forming efficiency and complete regio-,chemo-and stereoselectivity.展开更多
文摘perfluoroalkyl iodides reacted with alkenes in acetonitrile solu- tion containing catalytic amount of organophosphine under mild condition to give the corresponding adducts in moderate to good yields.Reaction was shown to involve a free radical mechanism.
基金supported by the National Natural Science Foundation of China(No.22101073)the Key Teacher Project of Henan Province of China(No.2021GGJS025)China Postdoctoral Science Foundation(No.2020M672200).
文摘Skeletal editing of organophosphines is highly challenging owing to the high P-C bond dissociation energy.Herein,we report an efficient catalyst-and additive-free skeletal editing strategy to transform easily accessible ortho-chalcone based organophosphines into new and complex phosphine oxides,that are unattainable by conventional methods.Water is indispensable to this transformation and serves as the oxygen source to cleave P-C bonds.Interestingly,it is possible to achieve the peripheral modification of organophosphines into phosphonium salts in the absence of water.This water-controlled skeletal editing or peripheral modification strategy is embedded with the merits of high bond-and ring-forming efficiency and complete regio-,chemo-and stereoselectivity.
