目的:比较腹腔镜胰十二指肠切除术(LPD)与开腹胰十二指肠切除术(OPD)的临床疗效。方法:回顾性收集新疆医科大学第一附属医院2015年1月至2021年1月期间完成的33例腹腔镜胰十二指肠切除术患者及33例开腹胰十二指肠切除术患者资料。比较两...目的:比较腹腔镜胰十二指肠切除术(LPD)与开腹胰十二指肠切除术(OPD)的临床疗效。方法:回顾性收集新疆医科大学第一附属医院2015年1月至2021年1月期间完成的33例腹腔镜胰十二指肠切除术患者及33例开腹胰十二指肠切除术患者资料。比较两组手术时间,术中出血量,术中输血情况,术后排气时间,术后首次下床时间,术后住院天数,带管时间,住院总费用及术后并发症发生情况。结果:两组手术出血量,住院总费用无统计学差异(P > 0.05),手术时间LPD组大于OPD组(P 0.05)。结论:开腹和腹腔镜胰十二指肠切除术均安全有效,腹腔镜胰十二指肠切除术在不增加并发症的情况下,术后恢复优于开腹腹腔镜胰十二指肠切除术。Objective: To compare the clinical effects of laparoscopic pancreaticoduodenectomy (LPD) and open pancreaticoduodenectomy (OPD). Methods: The data of 33 patients with laparoscopic pancreaticoduodenectomy and 33 patients with open pancreaticoduodenectomy completed in the First Affiliated Hospital of Xinjiang Medical University from January 2015 to January 2021 were collected retrospectively. The operation time, intraoperative bleeding, intraoperative blood transfusion, postoperative exhaust time, the first time out of bed, postoperative hospital stay, tube time, total hospitalization cost and postoperative complications were compared between the two groups. Results: There was no significant difference in the amount of surgical bleeding and the total cost of hospitalization between the two groups (P > 0.05). The operation time in group LPD was greater than that in group OPD (P 0.05). Conclusion: Both open and laparoscopic pancreatoduodenectomy are safe and effective, and laparoscopic pancreatoduodenectomy offers better postoperative recovery than open and laparoscopic pancreatoduodenectomy without increasing complications.展开更多
AIM: To compare the wavefront aberrations and corneal surface regularity between dry eye(DE) patients and normal subjects and assess its diagnostic performance for DE measured with OPD Scan-Ⅲ.METHODS: Fifty right eye...AIM: To compare the wavefront aberrations and corneal surface regularity between dry eye(DE) patients and normal subjects and assess its diagnostic performance for DE measured with OPD Scan-Ⅲ.METHODS: Fifty right eyes of 50 DE patients and 31 right eyes of normal subjects were included.The examinations for ocular surface including logarithm of the minimum angle of resolution best-corrected distance visual acuity(logMAR BCVA) the ocular surface disease index(OSDI), tear film break-up time(TBUT) and corneal fluorescein staining(CFS).OPD Scan-Ⅲ was used to measure anterior corneal aberrations including total corneal aberrations, high order aberration(HOA), coma, trefoil, spherical aberration(SA), standard deviation of corneal power(SDP), surface regularity index(SRI) and surface asymmetry index(SAI).Statistical analysis were assessed with nonparametric tests and Spearman’s correlations.All parameters were also analyzed for sensitivity, specificity, and receiver operating characteristics(ROC) curves.RESULTS: Wavefront aberrations parameters including total corneal aberrations, HOA, coma, trefoil, and SA in DE group were significantly higher than those in normal group(P<0.001).Corneal surface regularity parameters including SRI and SAI in DE group were significantly higher than both in normal group(P<0.05).All the wavefront aberrations parameters had significant correlations with ocular surface parameters(P<0.05).The logMAR BCVA had positive correlations with SAI and SRI(all P<0.001).CFS scores had positive correlations with SAI and SRI(all P<0.001).All the wavefront aberrations parameters showed good diagnosis sensitivity and specificity, however, the corneal regularity parameters showed only good specificity but poor sensitivity.The cut-off value selected for trefoil in diagnosis DE showed the highest area under the curve(AUC, 0.921) values as compared to the other parameters with sensitivity of 0.955 and specificity of 0.867.CONCLUSION: Wavefront aberrations and corneal surface regularity are increased in DE patients and also correlated with ocular surface parameters.Wavefront aberrations parameters have potential to be indicators to diagnosis and monitor DE.展开更多
文摘目的:比较腹腔镜胰十二指肠切除术(LPD)与开腹胰十二指肠切除术(OPD)的临床疗效。方法:回顾性收集新疆医科大学第一附属医院2015年1月至2021年1月期间完成的33例腹腔镜胰十二指肠切除术患者及33例开腹胰十二指肠切除术患者资料。比较两组手术时间,术中出血量,术中输血情况,术后排气时间,术后首次下床时间,术后住院天数,带管时间,住院总费用及术后并发症发生情况。结果:两组手术出血量,住院总费用无统计学差异(P > 0.05),手术时间LPD组大于OPD组(P 0.05)。结论:开腹和腹腔镜胰十二指肠切除术均安全有效,腹腔镜胰十二指肠切除术在不增加并发症的情况下,术后恢复优于开腹腹腔镜胰十二指肠切除术。Objective: To compare the clinical effects of laparoscopic pancreaticoduodenectomy (LPD) and open pancreaticoduodenectomy (OPD). Methods: The data of 33 patients with laparoscopic pancreaticoduodenectomy and 33 patients with open pancreaticoduodenectomy completed in the First Affiliated Hospital of Xinjiang Medical University from January 2015 to January 2021 were collected retrospectively. The operation time, intraoperative bleeding, intraoperative blood transfusion, postoperative exhaust time, the first time out of bed, postoperative hospital stay, tube time, total hospitalization cost and postoperative complications were compared between the two groups. Results: There was no significant difference in the amount of surgical bleeding and the total cost of hospitalization between the two groups (P > 0.05). The operation time in group LPD was greater than that in group OPD (P 0.05). Conclusion: Both open and laparoscopic pancreatoduodenectomy are safe and effective, and laparoscopic pancreatoduodenectomy offers better postoperative recovery than open and laparoscopic pancreatoduodenectomy without increasing complications.
文摘AIM: To compare the wavefront aberrations and corneal surface regularity between dry eye(DE) patients and normal subjects and assess its diagnostic performance for DE measured with OPD Scan-Ⅲ.METHODS: Fifty right eyes of 50 DE patients and 31 right eyes of normal subjects were included.The examinations for ocular surface including logarithm of the minimum angle of resolution best-corrected distance visual acuity(logMAR BCVA) the ocular surface disease index(OSDI), tear film break-up time(TBUT) and corneal fluorescein staining(CFS).OPD Scan-Ⅲ was used to measure anterior corneal aberrations including total corneal aberrations, high order aberration(HOA), coma, trefoil, spherical aberration(SA), standard deviation of corneal power(SDP), surface regularity index(SRI) and surface asymmetry index(SAI).Statistical analysis were assessed with nonparametric tests and Spearman’s correlations.All parameters were also analyzed for sensitivity, specificity, and receiver operating characteristics(ROC) curves.RESULTS: Wavefront aberrations parameters including total corneal aberrations, HOA, coma, trefoil, and SA in DE group were significantly higher than those in normal group(P<0.001).Corneal surface regularity parameters including SRI and SAI in DE group were significantly higher than both in normal group(P<0.05).All the wavefront aberrations parameters had significant correlations with ocular surface parameters(P<0.05).The logMAR BCVA had positive correlations with SAI and SRI(all P<0.001).CFS scores had positive correlations with SAI and SRI(all P<0.001).All the wavefront aberrations parameters showed good diagnosis sensitivity and specificity, however, the corneal regularity parameters showed only good specificity but poor sensitivity.The cut-off value selected for trefoil in diagnosis DE showed the highest area under the curve(AUC, 0.921) values as compared to the other parameters with sensitivity of 0.955 and specificity of 0.867.CONCLUSION: Wavefront aberrations and corneal surface regularity are increased in DE patients and also correlated with ocular surface parameters.Wavefront aberrations parameters have potential to be indicators to diagnosis and monitor DE.
