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Health Disparities Between Empty-Nest and Non-Empty-Nest Older Adults in Anhui,China:A Cross-Sectional Study
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作者 Li Chen Li Xing 《全球城市研究(中英文)》 2025年第3期29-49,149,共22页
This study aims to systematically explore the differences in health status between empty-nest and non-empty-nest older adults and further analyze the potential impact of empty-nest and non-empty-nest status on their p... This study aims to systematically explore the differences in health status between empty-nest and non-empty-nest older adults and further analyze the potential impact of empty-nest and non-empty-nest status on their physical and mental health.The study surveyed older adult populations in Anhui Province(N=379,average age=69.51 years)to assess their mental and physical health.Correlation analysis,multiple linear regression analysis,and propensity score matching were used to quantify the health differences between empty-nest and non-empty-nest older adults.Multiple linear regression analysis showed that empty-nest status has a significant positive impact on mental health but a negative impact on physical health.Propensity score matching analysis further validated the main findings of the multiple regression analysis.These findings should be interpreted within specific contexts and conditions,considering individual characteristics and historical perspectives,and fully considering the actual circumstances of the respondents. 展开更多
关键词 Empty-Nest older Adults Non-Empty-Nest older Adults Health Differences Anhui Province
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Demographic trends in mortality with older population due to atrial fibrillation and flutter from 1999-2020 被引量:1
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作者 Mahnoor Sukaina Marium Waheed +2 位作者 Shafi Rehman Md Al Hasibuzzaman Rabab Meghani 《World Journal of Cardiology》 2025年第1期1-7,共7页
Atrial fibrillation(AF)/atrial flutter(AFL)is the most common sustained cardiac arrhythmia.The known risk factors for developing AF/AFL include age,structural heart disease,hypertension,diabetes mellitus,or hyperthyro... Atrial fibrillation(AF)/atrial flutter(AFL)is the most common sustained cardiac arrhythmia.The known risk factors for developing AF/AFL include age,structural heart disease,hypertension,diabetes mellitus,or hyperthyroidism.This study aims to attribute the trends in AF/AFL-related mortalities over the past two decades 1999-2020 concerning race and sex and disparity among them.To the best of our knowledge,this is the first study that estimates the trends and mortality due to AF/AFL from 1999-2020 in older adults in the United States.In this 21-year analysis of mortality data,we found a constant increase in mortality rates due to AF/AFL in older adults.From 1999 to 2020,the overall mortality in older adults aged 65 and above,regardless of sex and race,is found to be almost doubled i.e.about a 50.2%increase in the number of deaths due to AF/AFL.Furthermore,other confounding risk factors such has obesity,prior myocardial infarction,inflammation,hypertension,birth weight,diabetes mellitus,hyperthyroidism,hormone replacement therapy in menopausal women increases the risk in the occurrence or recurrent occurrence of AF. 展开更多
关键词 Demographic trends United States Atrial fibrillation Atrial flutter older population
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Classifying Cognitive Decline in Older Drivers from Behavior on Adverse Roads Detected Using Computer Vision
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作者 Md Zahid Hasan Guillermo Basulto-Elias +5 位作者 Shauna Hallmark Jun Ha Chang Anuj Sharma Jeffrey D. Dawson Soumik Sarkar Matthew Rizzo 《Journal of Transportation Technologies》 2025年第1期135-154,共20页
As drivers age, roadway conditions may become more challenging, particularly when normal aging is coupled with cognitive decline. Driving during lower visibility conditions, such as inclement weather, is especially ch... As drivers age, roadway conditions may become more challenging, particularly when normal aging is coupled with cognitive decline. Driving during lower visibility conditions, such as inclement weather, is especially challenging for older drivers due to their sensitivity to glare and reduced visibility. As a result, older drivers may adjust their behavior during adverse weather. This paper explores the differential impacts of weather on older drivers with cognitive decline compared to older drivers with normal cognitive function. Data were from a naturalistic driving study of older drivers in Omaha, Nebraska. Driver speed and weather data were extracted and the correlation between speed compliance, road weather conditions, and the cognitive/neurological status of the drivers was examined. Speed compliance was used as the surrogate safety measure since driving at lower speeds can indicate that the driver is challenged by roadway or environmental conditions and can therefore indicate a risk. The percentage of time during a trip when drivers were 16.1 kph under the speed limit was modeled as the dependent variable using beta regression. The variables that resulted in the best fit model were mild cognitive impairment (MCI), age group, traffic density, and weather. Results indicated that the youngest group of older drivers (young-old) spent less time driving at impeding speeds and had the least variability compared to the other two age groups. The middle group of older drivers (middle-old) had the highest amount of time driving at impeding speeds and had more variability than young-old drivers. The oldest group of older drivers (old-old) were the most likely to drive at impeding speeds and had the most variability. In general, older drivers were more likely to drive at impeding speeds during peak hours than during non-peak hours. Additionally, in most cases, older drivers spent less time below the speed limit when the weather was clear than in adverse conditions. Results indicate that older drivers are impacted by weather conditions, and distinct patterns were noted between older drivers who were cognitively impaired compared to drivers with normal cognition. 展开更多
关键词 Traffic Safety older Driver Cognitive Impairment Machine Learning SPEED
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Beyond silence:Addressing mental health challenges and hopeful pathways for older adults
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作者 Elif Sarac 《World Journal of Psychiatry》 2025年第12期18-22,共5页
In this editorial,I comment on the article conducted by Yang and Woo.Mental health in older adults remains underserved and underexamined,with final decades shaped by cumulative life stressors,chronic conditions,and so... In this editorial,I comment on the article conducted by Yang and Woo.Mental health in older adults remains underserved and underexamined,with final decades shaped by cumulative life stressors,chronic conditions,and social determinants that disproportionately affect marginalized communities.In this study,I would like to synthesize current evidence on the prevalence,presentation,and trajectories of mental health concerns among older adults,highlighting common challenges such as late-life depression,anxiety,cognitive concerns,and underutilization of care.I am going to examine barriers to outreach and treatment,including stigma,cultural and linguistic mismatches,access limitations,and gaps in geriatric mental health services.The analysis in the paper identifies promising pathways to improve outcomes:Community-engaged interventions,culturally tailored care models,integration of mental health with primary and geriatric care,and policy reforms to expand coverage and reduce disparities.As a conclusion,with actionable recommendations for clinicians,researchers,policymakers,and community organizations to break the silence,enhance early detection,and foster resilient aging through equitable,person-centered approaches. 展开更多
关键词 Mental health older adults CHALLENGE STIGMA PATHWAYS
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Future anxiety and belongingness in young and older adults:An empirical study
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作者 Elif Sarac Esra Yıldız 《World Journal of Psychiatry》 2025年第6期210-219,共10页
BACKGROUND Human beings,by nature,have many expectations that create a feeling of anxiety about the future,but they are endured and long-ranged.They expect to have relationships with others and need to perceive an emo... BACKGROUND Human beings,by nature,have many expectations that create a feeling of anxiety about the future,but they are endured and long-ranged.They expect to have relationships with others and need to perceive an emotional interest,an interpersonal bond,and sustainment to continue living.Perceiving this link is required for feelings of belongingness,which decreases future anxiety.AIM To investigate the future anxiety and belongingness of young and older adults and determine their relationships.METHODS The study was conducted with 404 volunteer participants.Data were collected using the demographic characteristics from the“Dark Future Scale”and“General Belongingness Scale”.RESULTS The mean age of older adults was 66.76±3.74,while that of younger adults was 36.72±10.12.The average score for“future anxiety”was 18.81±7.59,and for“general belongingness",it was 63.31±1.40.Findings indicated a reverse correlation between future anxiety and belongingness.A significant difference in belonging scores was observed between young and older adults(P=0.016,which is<0.05),whereas no significant difference was found regarding future anxiety scores(P>0.05).CONCLUSION Participants had a moderate level of“future anxiety”and higher“belongingness”.Lower belongingness scores correlated with increased future anxiety.Older adults reported a lower sense of belonging than younger individuals. 展开更多
关键词 Future anxiety BELONGINGNESS older adults Youngers Mental well-being
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Walking sports and subjective wellbeing in older adults:a comparative study
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作者 Ishan Paranjape Alyson Crozier +1 位作者 Michelle Guerin Brad J.Stenner 《Translational Exercise Biomedicine》 2025年第3期178-187,共10页
Objectives:Walking sports,whereby traditional disciplines of sport modify gameplay by limiting physical activity to walking only,may offer benefits for physical activity engagement and subjective wellbeing outcomes in... Objectives:Walking sports,whereby traditional disciplines of sport modify gameplay by limiting physical activity to walking only,may offer benefits for physical activity engagement and subjective wellbeing outcomes in older adults.Questionnaires were used to collect physical activity and health related data from a cross section of older South Australian walking sports participants(n=56),which was compared to a population-based sample of their peers(n=1817)to explore these potential benefits.Methods:Ordinal logistic regression and linear regression were used for between-group comparisons across three subgroups of participants,who reported engaging in:(1)walking sports,(2)traditional sports,and(3)no sport.All analyses were adjusted for age,marital status,education and employment status.Results:Compared to walking sports participants,those who did not participate in sports were more than twice as likely to report poorer self-rated health.Walking sports and traditional sports participants reported meeting the minimum weekly physical activity requirements.No significant differences in subjective wellbeing were found between the three participant subgroups.Conclusions:Older adults who participated in walking sports had significantly higher self-rated health and physical activity levels,than those not involved in sports.Therefore,sport organisations should consider offering walking sports programs to engage older adults who face barriers to engaging in traditional sports,supporting their continued involvement in physical activity. 展开更多
关键词 psychological benefits EXERCISE older adults adapted sport wellbeing
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Evidence-based nursing to reduce polypharmacy risks in older cholecystectomy patients
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作者 Yu-Hua Deng Cai-Fang Zeng Jing Zhou 《World Journal of Gastrointestinal Surgery》 2025年第12期266-275,共10页
BACKGROUND With an aging society,older patients undergoing cholecystectomy often have multiple chronic diseases and require long-term multi-medication.Medication complexity significantly increases the risk of medicati... BACKGROUND With an aging society,older patients undergoing cholecystectomy often have multiple chronic diseases and require long-term multi-medication.Medication complexity significantly increases the risk of medication errors and adverse reactions,and effective nursing interventions are urgently required to ensure medication safety.AIM To investigate the efficacy of evidence-based nursing practices in mitigating polypharmacy risks among Suzhou Municipal Hospital Road Front Yard Area,thereby providing clinical guidance.METHODS The sixty older patients who underwent cholecystectomy between September 2024 and September 2025 treated with polypharmacy were enrolled.Using random number tables,hey were divided into study and control groups(n=30 each),who received routine medication nursing and evidence-based nursing,respectively.Pre-intervention and post-intervention comparisons were made between groups for medication knowledge,competence,and adherence scores.The incidences of duplicate medications,missed doses,self-discontinuation,unauthorized alterations,schedule changes,and adverse reaction rates assessed potential medication risks.RESULTS Both the study and control groups showed significant increases in medication knowledge,management competence,and adherence scores after intervention(all P<0.05).The study group had higher post-intervention scores(medication knowledge:87.29±5.09 vs 70.62±5.38;medication management competence:63.22±3.11 vs 56.19±4.08;medication adherence:7.13±1.04 vs 6.05±1.03,all P<0.05).The incidence of duplicate medication,missed doses,self-discontinuation,unauthorized dose alterations,and schedule modifications decreased in both groups post-intervention(all P<0.05),with lower rates in the study group(duplicate medication:13.33%vs 30.0%;missed doses:10.0%vs 26.67%;all P<0.05).The study group had a lower adverse reaction rate(3.33%vs 26.67%,P<0.05)and more patients with potential medication hazard level 0(83.33%vs 53.33%),while fewer patients had level 2 and 3 hazards(3.33%vs 16.67%and 0%vs 10.00%,respectively;all P<0.05).CONCLUSION Evidence-based nursing for polypharmacy risks in older adults undergoing cholecystectomy can enhance medication awareness,improve management and adherence,reduce adverse behaviors,and lower adverse reactions and hazard levels. 展开更多
关键词 Evidence-based nursing POLYPHARMACY older patients CHOLECYSTECTOMY Risk management
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Empowering older adults: Enhancing addiction literacy to address unique vulnerabilities
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作者 Kae Leopoldo Joao Mauricio Castaldelli-Maia 《World Journal of Psychiatry》 2025年第7期310-312,共3页
Addiction literacy equips older adults with the knowledge to navigate substance use risks amid unique challenges like polypharmacy and social isolation.With rising trends in cannabis use among this group,targeted educ... Addiction literacy equips older adults with the knowledge to navigate substance use risks amid unique challenges like polypharmacy and social isolation.With rising trends in cannabis use among this group,targeted education can promote safe practices and reduce preventable harms.By fostering open conversations and integrating addiction literacy into healthcare,providers can support informed decision-making. 展开更多
关键词 Health literacy Addiction literacy Ageing older adults Drug use POLYPHARMACY
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The development and application of the mobile frailty management platform for Chinese community-dwelling older adults
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作者 Jjiayi Hou Xinrui Wan +1 位作者 Mengjie Li Gujuan He 《International Journal of Nursing Sciences》 2025年第2期115-122,I0001,共9页
Objectives:This study aimed to develop a mobile frailty management platform for Chinese communitydwelling older adults and evaluate its effectiveness,usability and safety.Methods:Based on literature research,the resea... Objectives:This study aimed to develop a mobile frailty management platform for Chinese communitydwelling older adults and evaluate its effectiveness,usability and safety.Methods:Based on literature research,the research team combined the frailty cycle and integration models,self-determination theory,and technology acceptance models and determined the frailty interventions through expert discussion,then transformed it into multimedia resources,finally,engineers developed the mobile management platform.A cluster sampling,parallel,single-blind,controlled quasiexperimental trial was conducted.Sixty older adults from two community health service centers were recruited from March to August 2023.The control group received routine community care,while the intervention group used the mobile frailty management platform.The incidence of frailty,scores of quality of life,depression,sleep quality,and grip strength within 12 weeks were compared between the two groups,and the availability and safety of the platform were assessed.Results:A total of 52 participants completed the study,27 in the intervention group and 25 in the control group.At 12 weeks after the intervention,the frailty state of the intervention group was reversed to prefrailty.There were no significant differences in the scores of quality of life,depression,sleep quality,and grip strength between the two groups before and 4 weeks after intervention.At 8 weeks and 12 weeks after the intervention,the quality of life,depression,and grip strength of the intervention group were improved with statistical significance(P<0.05).Sleep quality was statistically significant only 12 weeks after the intervention(P<0.05).System Usability Scale score for the platform was(87.96±5.88),indicating a highly satisfactory user experience.Throughout the intervention,no adverse events were reported among the older adults.Conclusions:The mobile frailty management platform effectively improved frailty status,depressive mood,sleep quality,grip strength,and quality of life for Chinese community-dwelling older adults.It holds clinical application value and is an effective tool for strengthening frailty management among Chinese community-dwelling older adults. 展开更多
关键词 COMMUNITY FRAILTY Mobile health older adults Quasi-experimental trial Qualityof life Sleep quality
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Falls in older persons living with heart failure-taking a step back&thinking beyond GDMTs
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作者 Nur Ezzati Alias Aimy Abdullah +2 位作者 Norashikin Saidon Noor Azleen Ahmad Tarmizi Raja Ezman Raja Shariff 《Journal of Geriatric Cardiology》 2025年第7期695-700,共6页
Falls remain a prevalent source of injury in daily life and underlying aetiology of falls are often complex and multi-factorial.[1,2]Older persons living with heart failure(OPLHF)are of a particular interest when disc... Falls remain a prevalent source of injury in daily life and underlying aetiology of falls are often complex and multi-factorial.[1,2]Older persons living with heart failure(OPLHF)are of a particular interest when discussing falls as multiple factors associated with heart failure(HF)aetiology and treatment are assumedly implicated in falls occurrence.A retrospective study reported a 14%increased risk of falls among OPLHF,and prospective data has shown that up to 40%of HF patients may experience a fall within a year from diagnosis. 展开更多
关键词 prospective data multi factorial heart failure oplhf FALLS risk heart failure AETIOLOGY older persons
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Mental health of older Asian Americans:Current issues,updates,and future directions
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作者 Chiana Q Yang Benjamin K P Woo 《World Journal of Psychiatry》 2025年第8期88-97,共10页
As the population of older Asian Americans continues to grow rapidly,understanding their mental health needs has become increasingly critical.This literature review summarizes current issues,developments,and future di... As the population of older Asian Americans continues to grow rapidly,understanding their mental health needs has become increasingly critical.This literature review summarizes current issues,developments,and future directions in addressing the mental health challenges faced by older Asian Americans in the last five years.We briefly touch on the comparative prevalence of mental health disorders experienced by ethnic subgroups.Additionally,we review recent studies highlighting the role of the coronavirus disease 2019,racism,social support,cultural stigma,and self-rated health as significant factors influencing mental well-being of this population.We discuss the utilization of health services among older Asian Americans.We conclude with thoughts for future research,emphasizing the importance of longitudinal studies,consideration of diverse Asian American ethnic subgroups,and culturally sensitive diagnostic and treatment approaches. 展开更多
关键词 Asian American older AGING Mental health Mental illness COVID-19 RACISM Social support STIGMA Self-rated health
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Analysis of current state of participation in medication safety behavior and influencing factors in older adults with chronic disease during the hospital-to-home transition : a cross-sectional study
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作者 Xiao-Yan Lin Wei-Xi Xu +2 位作者 Hui-Qi Lai Ya-Qin Ren Ting Lin 《Nursing Communications》 2025年第24期1-9,共9页
Background:Patient participation is crucial for medication safety among older adults with chronic diseases transitioning from hospital to home,yet evidence on its levels and influencing factors remains limited.This st... Background:Patient participation is crucial for medication safety among older adults with chronic diseases transitioning from hospital to home,yet evidence on its levels and influencing factors remains limited.This study investigated the current state and predictors of such participation during this critical period.Methods:A cross-sectional study was conducted among older adults discharged from two tertiary hospitals in Fujian,China(October-December 2023).Data were collected using a general information questionnaire,a self-developed behavior scale,the Health Literacy Management Scale,General Self-Efficacy Scale,Facilitation of Patient Involvement Scale,and Family Support Scale.Analyses included ANOVA,Pearson correlation,and multiple stepwise regression.Results:Among 302 valid responses,the mean score for participation in medication safety behaviors was 68.59±11.62,indicating a moderate level.Health literacy,self-efficacy,healthcare worker support,and family support were positively correlated with participation(all P<0.01).Multiple regression identified daily medication frequency,health literacy,self-efficacy,and healthcare worker support as significant predictors,explaining 18.3%of the variance.Conclusion:Participation in medication safety among older chronic disease patients during care transitions requires improvement.Enhancing health literacy,self-efficacy,and healthcare worker support,while considering medication frequency,can promote patient involvement and medication safety. 展开更多
关键词 hospital-to-home transition older adults chronic disease patient involvement medication safety
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Thirst experience and nursing needs in older patients after general anesthesia for gastrointestinal surgery:A qualitative study
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作者 Ting Li Wen-Hui Dong +2 位作者 Shuo Wang Ying Wu Shu-Yan Wang 《World Journal of Gastrointestinal Surgery》 2025年第5期257-265,共9页
BACKGROUND Older patients often experience thirst after general anesthesia for gastrointestinal surgery,particularly during the post-anesthesia care unit(PACU)phase.Thirst not only compromises patient comfort but also... BACKGROUND Older patients often experience thirst after general anesthesia for gastrointestinal surgery,particularly during the post-anesthesia care unit(PACU)phase.Thirst not only compromises patient comfort but also induces anxiety,which may hinder recovery.Although previous studies have addressed postoperative thirst,research specifically examining thirst experiences and nursing needs in older patients remains limited.AIM To explore thirst experiences and nursing needs of older PACU patients following gastrointestinal surgery,aiming to inform targeted interventions.METHODS This study employed a phenomenological approach within a qualitative research framework.A purposeful sampling method was used to select 12 older patients who underwent gastrointestinal surgery under general anesthesia at a tertiary hospital in Shanghai between November and December 2024.Data were collected through semi-structured interviews and analyzed using Colaizzi’s seven-step method.Themes were extracted from the interview data.RESULTS Analysis of the interview data identified four main themes and eight subthemes:(1)Intense sensations of thirst post-surgery(subjective experience of thirst and duration of thirst);(2)Emotional experiences of thirst-related discomfort(anxiety,irritability,and helplessness);(3)Practical challenges in relieving thirst(limitations of current interventions and nursing response time);and(4)Patient expectations of nursing care(desire for more timely interventions and expectation for more proactive attention from nursing staff).CONCLUSION Older patients frequently experience substantial thirst discomfort after gastrointestinal surgery under general anesthesia.A multidisciplinary perioperative intervention plan is essential to alleviate these symptoms and enhance postoperative comfort. 展开更多
关键词 older people General anesthesia Gastrointestinal surgery Thirst experience NURSING Qualitative research
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Digital literacy and subjective well-being among older adults:The chain mediating effect of physical exercise and consumption
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作者 Jiahan Li You Zhou +1 位作者 Jie Yang Lei Yuan 《Journal of Psychology in Africa》 2025年第2期249-256,共8页
Subjective well-being is a key indicator of quality of life and a crucial factor for successful aging among older adults.However,few studies have explored the subjective well-being among older adults from the perspect... Subjective well-being is a key indicator of quality of life and a crucial factor for successful aging among older adults.However,few studies have explored the subjective well-being among older adults from the perspective of digital literacy.Therefore,this study explores the relationship between digital literacy and subjective well-being using data on 4270 older adults from the 2020 China Family Panel Studies(CFPS)dataset.PROCESS mediation analysis results indicated digital literacy is associated with higher subjective well-being among the older adults.Digital literacy was associated with the frequency of physical exercise and consumption.Moreover,Digital literacy can also enhance the subjective well-being among older adults by increasing the frequency of physical exercise,and consumption,and a chain mediator subjective well-being.These findings align with the theoretical framework of digital health literacy.Theory which posits that health information obtained through digital literacy can help older adults better engage in healthy lifestyles,thereby enhancing their quality of life.These findings hold significant practical implications for enhancing the subjective well-being among older adults and advancing the development of successful aging. 展开更多
关键词 digital literacy subjective well-being physical exercise CONSUMPTION older adults
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Effect of stratified management and stepwise training on pulmonary rehabilitation in older patients with liver cancer
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作者 Qiao Zhang Chang-Dan Liu +3 位作者 Xiao-Xiao Lu Shu-Shan Zhang Jian-Hua Gong Juan Ding 《World Journal of Gastrointestinal Surgery》 2025年第11期316-324,共9页
BACKGROUND Older patients with liver cancer often experience impaired pulmonary function post-surgery,increasing complications and recovery challenges.AIM To investigate the effects of evidence-based stratified manage... BACKGROUND Older patients with liver cancer often experience impaired pulmonary function post-surgery,increasing complications and recovery challenges.AIM To investigate the effects of evidence-based stratified management and stepwise training in the perioperative pulmonary rehabilitation of older patients with liver cancer,providing a basis for clinical application.METHODS In total,120 older patients with liver cancer who underwent surgery at our hospital between February 2023 and February 2025 were selected and randomly divided into study and control groups,with 60 patients in each group.All the patients underwent radical hepatectomy.Postoperatively,the control group received routine nursing management and rehabilitation training,while the study group received evidence-based stratified management combined with stepwise training for a continuous intervention period of one week.Time to first ambulation,length of hospital stays,and average hospitalization costs were recorded.Oxygen saturation(SPO_(2))was measured on postoperative day 1 and day 3.The 6-minute walk distance and Borg scale scores were assessed on postoperative day 1 and day 7,respectively.The postoperative complication rates were recorded.RESULTS The study group had a significantly shorter time to first ambulation,shorter hospital stays,and lower average hospitalization costs than the control group(P<0.05).On postoperative day 1,there was no significant difference in SPO_(2)between the groups(P>0.05);however,on postoperative day 3,the study group had significantly higher SPO_(2)(P<0.05).On postoperative day 7,the study group showed a significantly longer 6-minute walk distance and lower Borg scores than the control group(P<0.05).The incidence of postoperative complications in the study group was 3.33%,which was significantly lower than that in the control group(13.33%;P<0.05).CONCLUSION Implementing evidence-based stratified management combined with stepwise training in the perioperative pulmonary rehabilitation of older patients with liver cancer is improves lung function,reduces complications,and promotes effective recovery,demonstrating significant clinical value. 展开更多
关键词 Evidence-based stratified management Stepwise training older patients Liver cancer Perioperative Pulmonary rehabilitation
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Association between Organochlorine Exposures and Lung Functions Modified by Thyroid Hormones and Mediated by Inflammatory Factors among Healthy Older Adults
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作者 Xiaojie Guo Huimin Ren +5 位作者 Jiran Zhang Xiao Ma Shilu Tong Song Tang Chen Mao Xiaoming Shi 《Biomedical and Environmental Sciences》 2025年第2期144-153,共10页
Objective To examine the mechanistic of organochlorine-associated changes in lung function.Methods This study investigated 76 healthy older adults in Jinan,Shandong Province,over a fivemonth period.Personal exposure t... Objective To examine the mechanistic of organochlorine-associated changes in lung function.Methods This study investigated 76 healthy older adults in Jinan,Shandong Province,over a fivemonth period.Personal exposure to organochlorines was quantified using wearable passive samplers,while inflammatory factors and thyroid hormones were analyzed from blood samples.Participants’lung function was evaluated.After stratifying participants according to their thyroid hormone levels,we analyzed the differential effects of organochlorine exposure on lung function and inflammatory factors across the low and high thyroid hormone groups.Mediation analysis was further conducted to elucidate the relationships among organochlorine exposures,inflammatory factors,and lung function.Results Bis(2-chloro-1-methylethyl)ether(BCIE),was negatively associated with forced vital capacity(FVC,–2.05%,95%CI:–3.11%to–0.97%),and associated with changes in inflammatory factors such as interleukin(IL)-2,IL-7,IL-8,and IL-13 in the low thyroid hormone group.The mediation analysis indicated a mediating effect of IL-2(15.63%,95%CI:0.91%to 44.64%)and IL-13(13.94%,95%CI:0.52%to 41.07%)in the association between BCIE exposure and FVC.Conclusion Lung function and inflammatory factors exhibited an increased sensitivity to organochlorine exposure at lower thyroid hormone levels,with inflammatory factors potentially mediating the adverse effects of organochlorines on lung function. 展开更多
关键词 Healthy older adults Inflammatory factors Lung function ORGANOCHLORINES Thyroid hormones
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Effectiveness of a multi-modal intervention protocol for preventing stress ulcers in critically ill older patients after gastrointestinal surgery
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作者 Hai-Ming Xi Man-Li Tian +3 位作者 Ya-Li Tian Hui Liu Yun Wang Min-Juan Chu 《World Journal of Gastrointestinal Surgery》 2025年第4期316-323,共8页
BACKGROUND Stress ulcers are common complications in critically ill patients,with a higher incidence observed in older patients following gastrointestinal surgery.This study aimed to develop and evaluate the effective... BACKGROUND Stress ulcers are common complications in critically ill patients,with a higher incidence observed in older patients following gastrointestinal surgery.This study aimed to develop and evaluate the effectiveness of a multi-modal intervention protocol to prevent stress ulcers in this high-risk population.AIM To assess the impact of a multi-modal intervention on preventing stress ulcers in older intensive care unit(ICU)patients postoperatively.METHODS A randomized controlled trial involving critically ill patients(aged≥65 years)admitted to the ICU after gastrointestinal surgery was conducted.Patients were randomly assigned to either the intervention group,which received a multimodal stress ulcer prevention protocol,or the control group,which received standard care.The primary outcome measure was the incidence of stress ulcers.The secondary outcomes included ulcer healing time,complication rates,and length of hospital stay.RESULTS A total of 200 patients(100 in each group)were included in this study.The intervention group exhibited a significantly lower incidence of stress ulcers than the control group(15%vs 30%,P<0.01).Additionally,the intervention group demonstrated shorter ulcer healing times(mean 5.2 vs 7.8 days,P<0.05),lower complication rates(10%vs 22%,P<0.05),and reduced length of hospital stay(mean 12.3 vs 15.7 days,P<0.05).CONCLUSION This multi-modal intervention protocol significantly reduced the incidence of stress ulcers and improved clinical outcomes in critically ill older patients after gastrointestinal surgery.This comprehensive approach may provide a valuable strategy for managing high-risk populations in intensive care settings. 展开更多
关键词 Stress ulcers older patients Gastrointestinal surgery Critical care Multi-modal intervention
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Effect of a wearable-sensor-assisted multicomponent exercise program on physical fitness,cognition and quality of life in frail older adults
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作者 Genghong Tu Lining Liu +2 位作者 Huiyi Tang Weizhong Chen Bagen Liao 《Translational Exercise Biomedicine》 2025年第3期201-215,共15页
Objectives:To assess the effects of a wearable-sensorassisted multicomponent exercise program on physical fitness,cognition and quality of life in a practical setting involving frail older adults.Methods:Frail older a... Objectives:To assess the effects of a wearable-sensorassisted multicomponent exercise program on physical fitness,cognition and quality of life in a practical setting involving frail older adults.Methods:Frail older adults(n=130)were randomly divided into a control(CG,n=68)group and an exercise group(EG,n=62)in a 12-week intervention,which included stride gait training with wearable sensors;aerobic exercise;and resistance,flexibility,balance,and cognitive training.Primary outcomes(physical fitness)were evaluated via the SPPB and SFT.Secondary outcomes(cognitive ability,quality of life and frailty)were evaluated via the MoCA-BC,SF-36 and Fried frailty criteria,respectively.Results:After the 12-week intervention,the EG demonstrated significant improvements(p<0.05)vs.the CG in gait speed(β_(3)=0.424,coefficient of interaction effect between group and time from the generalized linear mixed model),chair stand(β_(3)=0.501)and total score(β_(3)=65.466)of SPPB and all SFT components including 6MWT(walked distance,β_(3)=1.098;walking speed,β_(3)=0.105;stride length,β_(3)=0.041),back scratch(β_(3)=4.926),chair sit and reach(β_(3)=3.762),30s arm curl(β_(3)=6.124),30s sit-to-stand(β_(3)=3.04),and TUG(β_(3)=−6.712).The MoCA-BC total,verbal fluency and delayed recall scores;the physical function,general health,vitality,and mental health scores of the SF-36;and the frailty phenotype in the EG were significantly improved compared with those of the CG.Conclusions:The progressive wearable-sensor-assisted multicomponent exercise program designed in this study enhanced physical fitness,cognitive ability and quality of life and slowed down the progression of frailty in frail older adults,supporting its potential as a feasible communitybased health intervention. 展开更多
关键词 frail older adults multicomponent exercise physical fitness COGNITION quality of life
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Identification of risk factors for Clostridium difficile infection in older adult hospitalized patients with pressure ulcers
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作者 Qin Jiang Dong-Xin Liu +3 位作者 Wei Lu Hong-Fei Sang Xiao-Mei Gong Yu-Lei Li 《World Journal of Gastroenterology》 2025年第36期122-128,共7页
BACKGROUND Clostridium difficile(C.difficile)infection(CDI)is a common healthcare-associated infection.Older adult hospitalized patients with pressure ulcers are more sus-ceptible because of low immunity and disordere... BACKGROUND Clostridium difficile(C.difficile)infection(CDI)is a common healthcare-associated infection.Older adult hospitalized patients with pressure ulcers are more sus-ceptible because of low immunity and disordered flora,but their specific risk factors are unknown.This study hypothesizes that the use of antibiotics for more than 2 weeks,the use of proton pump inhibitors(PPIs),and the use ofβ-lactam antibiotics are independent risk factors for CDI in this population.METHODS A total of 120 older adults hospitalized with pressure ulcers from 2020 to 2023 were enrolled in the wound repair ward of the hospital.Stool samples were collected for anaerobic culture,C.difficile glutamate dehydrogenase(GDH)anti-gen and toxin detection,and multivariate logistic regression was used to analyze risk factors.RESULTS Among 120 older adults hospitalized patients with pressure ulcers,39 tested po-sitive for C.difficile,with an incidence rate of 32.5%.Thirty-nine patients(32.5%)were positive for GDH antigen.Twelve patients(10.0%)were positive for toxin A/B.Multivariate analysis shows that the use of antibiotics for more than 2 weeks,the use of proton pump inhibitors,and the use ofβ-lactam antibiotics are independent risk factors for CDI(all P values<0.05).CONCLUSION From 2020 to 2023,the incidence of CDI in 120 hospitalized older adult patients with pressure ulcers was 32.5%,and three independent risk factors were identified. 展开更多
关键词 older adult patients Pressure ulcers Wound repair ward Clostridium difficile INFECTION Risk factors DETECTION
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Nutritional psychiatry for hypertensive older adults
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作者 Takahiko Nagamine 《World Journal of Psychiatry》 2025年第6期15-20,共6页
Hypertension,a prevalent condition among older adults,has been identified as a risk factor for cognitive decline.Nutritional status is a pivotal factor in preserving cognitive function in hypertensive older adults.Nut... Hypertension,a prevalent condition among older adults,has been identified as a risk factor for cognitive decline.Nutritional status is a pivotal factor in preserving cognitive function in hypertensive older adults.Nutritional psychiatry underscores the significance of anti-inflammatory diets in promoting mental and cognitive health.This article examined the mechanisms by which body mass index,serum hemoglobin,serum albumin,and alkaline phosphatase levels predict cognitive function in hypertensive older adults.Nutrition emerges as a modifiable factor that can be targeted to maintain cognitive function in these patients. 展开更多
关键词 Nutritional psychiatry Hypertensive older adults Cognitive function Alkaline phosphatase Gut-brain axis
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