In this paper, it is shown that pterodonoic acid may or may not have the structure of 3-oxoeudesma-4,11-dien-12-oic acid 1 by comparison of their spectral data. But it is certainly not 10-epi-3-oxoeudesma-4,11-dien-12...In this paper, it is shown that pterodonoic acid may or may not have the structure of 3-oxoeudesma-4,11-dien-12-oic acid 1 by comparison of their spectral data. But it is certainly not 10-epi-3-oxoeudesma-4,11-dien-12-oic, acid 2, which is synthesized from dihydrocarvone 3.展开更多
目的:采用高效液相色谱法测定化合物ent-kaur-16-en-19-oic ac id在光叶番荔枝不同部位和番荔枝属不同种类植物叶子中的含量。方法:色谱条件为:Nuc leosil C18色谱柱,流动相选用乙睛:水(含1%冰醋酸)=67.5:32.5,检测波长211nm。结果:平...目的:采用高效液相色谱法测定化合物ent-kaur-16-en-19-oic ac id在光叶番荔枝不同部位和番荔枝属不同种类植物叶子中的含量。方法:色谱条件为:Nuc leosil C18色谱柱,流动相选用乙睛:水(含1%冰醋酸)=67.5:32.5,检测波长211nm。结果:平均回收率为98.41%,光叶番荔枝树皮、光叶番荔枝树枝(去皮)、光叶番荔枝树叶、AP番荔枝树叶、牛心番荔枝树叶、山刺番荔枝树叶中化合物ent-kaur-16-en-19-oic ac id的含量分别为0.7147%、0.01252%、0.01773%、0.04212%、0.007305%、0.09083%。结论:在光叶番荔枝各部位中,树皮的含量最高,达0.7147%,在所测番荔枝属植物的树叶中,山刺番荔枝树叶中含量最高,达0.09083%。展开更多
2β,3α--Dihydroxyurs-12-en-28-oic acid （6） is a naturally occurring diastereoisomer of corosolic acid with glycogen phosphorylase inhibitory activity. A new strategy for the semi-synthesis of 6 was developed. Using...2β,3α--Dihydroxyurs-12-en-28-oic acid （6） is a naturally occurring diastereoisomer of corosolic acid with glycogen phosphorylase inhibitory activity. A new strategy for the semi-synthesis of 6 was developed. Using the commercially available ursolic acid （1） as the starting materials, 6 was synthesized through five facile reactions with a high stereoselectivity and an overall yield of 47,3%, The structure of 6 was confirmed by optical rotation, ESI-MS, 1H NMR and 13C NMR data,展开更多
The present paper deals with the facile synthesis of 6 E geranylgeraniol 19 oic acid(1), a naturally occuring alicyclic diterpene acid, by a Horner Wadsworth Emmons olefination of two readily available fragments 7 and 3.
Facile synthesis of 6(E)-geranylgeraniol-19-oic acid 1, a naturally occurring alicyclic diterpene acid, by a Horner-Wadsworth-Emmons olefination of two readily available fragments 2 and 3, is described.
文摘In this paper, it is shown that pterodonoic acid may or may not have the structure of 3-oxoeudesma-4,11-dien-12-oic acid 1 by comparison of their spectral data. But it is certainly not 10-epi-3-oxoeudesma-4,11-dien-12-oic, acid 2, which is synthesized from dihydrocarvone 3.
文摘目的:采用高效液相色谱法测定化合物ent-kaur-16-en-19-oic ac id在光叶番荔枝不同部位和番荔枝属不同种类植物叶子中的含量。方法:色谱条件为:Nuc leosil C18色谱柱,流动相选用乙睛:水(含1%冰醋酸)=67.5:32.5,检测波长211nm。结果:平均回收率为98.41%,光叶番荔枝树皮、光叶番荔枝树枝(去皮)、光叶番荔枝树叶、AP番荔枝树叶、牛心番荔枝树叶、山刺番荔枝树叶中化合物ent-kaur-16-en-19-oic ac id的含量分别为0.7147%、0.01252%、0.01773%、0.04212%、0.007305%、0.09083%。结论:在光叶番荔枝各部位中,树皮的含量最高,达0.7147%,在所测番荔枝属植物的树叶中,山刺番荔枝树叶中含量最高,达0.09083%。
基金Financial support from the Fundamental Research Funds for the Central Universities(No.DUT12JB08)
文摘2β,3α--Dihydroxyurs-12-en-28-oic acid （6） is a naturally occurring diastereoisomer of corosolic acid with glycogen phosphorylase inhibitory activity. A new strategy for the semi-synthesis of 6 was developed. Using the commercially available ursolic acid （1） as the starting materials, 6 was synthesized through five facile reactions with a high stereoselectivity and an overall yield of 47,3%, The structure of 6 was confirmed by optical rotation, ESI-MS, 1H NMR and 13C NMR data,
基金Supported bytheNational Natural Science Foundation of China( No.2 0 0 72 0 12 ) and the Special Research Grant forDoctoral Sites in Chinese U niversities( No.2 0 0 10 730 0 0 1)
文摘The present paper deals with the facile synthesis of 6 E geranylgeraniol 19 oic acid(1), a naturally occuring alicyclic diterpene acid, by a Horner Wadsworth Emmons olefination of two readily available fragments 7 and 3.
基金supported by the National Natural Science Foundation of China(Grant No.20072012)the Foundation for University Key Teacher by the Ministry of Education of China
文摘Facile synthesis of 6(E)-geranylgeraniol-19-oic acid 1, a naturally occurring alicyclic diterpene acid, by a Horner-Wadsworth-Emmons olefination of two readily available fragments 2 and 3, is described.
文摘利用硅胶柱色谱反复层析从黄背越橘的乙酸乙酯部分分得7个化合物,根据理化性质和光谱数据鉴定,分别为β-谷甾醇(β-sitosterol,Ⅰ),熊果酸(ursolic acid,Ⅱ),蒲公英萜醇(taraxerol,Ⅲ),蒲公英萜酮(taraxerone,Ⅳ),木栓酮(friedelin,Ⅴ),木栓醇(friedelinol,Ⅵ),19,24-d ihydroxyurs-12-en-3-one-28-oic ac id(Ⅶ).
