The Antarctic Tianmu Staring Observation Project(ATSOP)entails the deployment of 30 small-aperture,wide-field optical telescopes in the Antarctic region.The system will perform long-term continuous observation campaig...The Antarctic Tianmu Staring Observation Project(ATSOP)entails the deployment of 30 small-aperture,wide-field optical telescopes in the Antarctic region.The system will perform long-term continuous observation campaigns over a period of 100 d(24 h per day)per year,as well as short-time-scale sampling at intervals of 5 min,across a sky area of approximately 1200 square degrees centered near the south celestial pole.We have assessed the types of small solar system bodies detectable by the ATSOP telescopes,as well as the associated scientific research opportunities.Our analysis indicates that the ATSOP is capable of detecting near-Earth objects(NEOs)with all orbital inclinations,as well as high-inclination small bodies located beyond the main asteroid belt.Potential research topics include the discovery and identification of small bodies,orbit determination,physical characterization,investigation into the activity characteristics and evolutionary patterns of active small bodies,and studies on their dynamical evolution.Observations of NEOs can also contribute to planetary defense efforts.On the basis of pilot observational data collected by the Antarctic Tianmu prototype(AT-Proto)between February 20 and October 26,2023,a total of 478 asteroids and 9 comets were successfully identified,demonstrating the effectiveness of the ATSOP system in observing small solar system bodies.Looking ahead,with anticipated performance enhancements in the second-generation AT-Proto,the limiting magnitude will increase from 16 to 18,thereby enabling the detection of an even greater number of small solar system bodies.展开更多
State Field Observation and Research Station of Debris Flow in Dongchuan,Yunnan is also named Dongchuan Debris Flow Observation and Research Station,Chinese Academy of Sciences.The study area,Jiangjia Ravine,is about ...State Field Observation and Research Station of Debris Flow in Dongchuan,Yunnan is also named Dongchuan Debris Flow Observation and Research Station,Chinese Academy of Sciences.The study area,Jiangjia Ravine,is about 48.6 km2 and characterized by intense tectonism.Accumulated clastic detritus is the main source of the materials in the debris flows when an intense rainfall occurs.The recorded highest density and sediment transport are 2370 kg/m^(3) and 6.079×10^(6) kg/s,respectively.The ravine is now called the“debris flow museum”in China and supplies advantageous research conditions.展开更多
Climate change,natural disasters,pollution,and fast urbanization have made environmental security a more serious international issue.Timely,accurate,and multi-dimensional information is essential in the effective moni...Climate change,natural disasters,pollution,and fast urbanization have made environmental security a more serious international issue.Timely,accurate,and multi-dimensional information is essential in the effective monitoring and management of such complex challenges in the environment.The Earth Observation(EO)systems,including optical sensors,radar sensors,Light Detection and Ranging(LiDAR)sensors,thermal sensors,Unmanned Aerial Vehicle(UAV)sensors,and in-situ sensors,offer a good coverage of space and time,as well as provide useful information on land,water,and atmospheric processes.But the shortcomings or weaknesses of individual sensors,such as their vulnerability to weather conditions,spectral or spatial resolution,and gaps in time,can tend to limit their ability to provide a complete picture of the environment.One of the solutions has been multi-sensor fusion,which combines heterogeneous data and makes it more accurate,robust,and interpretable.This systematic review analyzes the latest methods of multi-sensor fusion,which are machine learning,deep learning,probabilistic models,and hybrid approaches,in terms of methodological principles,preprocessing needs,and computational frameworks.Applications in environmental security are highlighted,which include monitoring natural disasters,monitoring of climate and ecosystem,pollution monitoring,monitoring of land use change,and early warning systems.The review also covers evaluation measures,validation plans,and uncertainty measures,where a strict measure of evaluation is vital to making actionable decisions.Lastly,emerging issues,e.g.,data heterogeneity,computational needs,sensor interoperability,and prospects in the future,e.g.,AI-based adaptive fusion,UAVs and Internet of Things(IoT)integration,and scalable cloud-based systems,are discussed.The synthesis has highlighted the transformational capability of multi-sensor EO in terms of improving the environment in the context of environmental security and sustainable management.展开更多
Energy transfers among internal waves in the northern South China Sea are not well characterized,particularly during typhoons,owing to the lack of in situ observations.Based on high-resolution mooring data collected d...Energy transfers among internal waves in the northern South China Sea are not well characterized,particularly during typhoons,owing to the lack of in situ observations.Based on high-resolution mooring data collected during Typhoon Trami(2024),this study reveals the occurrence of robust vertical energy redistribution among diurnal internal tides(D1 ITs)and near-inertial waves(NIWs).Strikingly,the typhoon not only amplified the NIW energy but also triggered an unexpected surge in the D1 IT energy.The observed average net energy transfer rate of 1×10^(-7) W kg^(−1) from typhoon-forced NIWs to D1 ITs occurred at water depths of 120-170 m.Further bispectral analysis indicated that the energy transfer is driven by nonlinear wave—wave interaction.These results reveal the existence of a new energy transfer pathway—from atmospheric forcing to D1 ITs—and redefine the redistribution of the internal wave energy during extreme weather events.展开更多
Objective:To evaluate the clinical efficacy of blood-letting cupping combined with manual lymphatic drainage in treating breast cancer-related lymphedema(BCRL)and explore its mechanism of action from both traditional ...Objective:To evaluate the clinical efficacy of blood-letting cupping combined with manual lymphatic drainage in treating breast cancer-related lymphedema(BCRL)and explore its mechanism of action from both traditional Chinese medicine and modern medical perspectives,providing a scientific basis and novel therapeutic approaches for clinical management of BCRL.Methods:Patients with BCRL admitted to the outpatient and inpatient departments of Hebei University Affiliated Hospital were enrolled.A prospective randomized controlled trial design was adopted,with eligible patients randomly assigned to a treatment group and a control group.The control group received manual lymphatic drainage alone,while the treatment group received manual lymphtic drainage combined with blood-letting cupping therapy.Posttreatment comparisons evaluated upper limb circumference reduction,edema severity grading,and upper limb functional scores.Vital signs and adverse reactions during treatment were recorded for both groups.Statistical software analyzed the data.Results:The treatment group demonstrated significantly greater reduction in upper limb circumference,improvement in edema severity,and higher upper limb function scores compared to the control group(P<0.05).Vital signs remained stable throughout treatment in both groups.No severe adverse reactions occurred in the treatment group;only isolated cases of mild skin itching were reported,which resolved after symptomatic management.Conclusion:The combination of bloodletting cupping and manual lymphatic drainage demonstrates reliable efficacy in treating BCRL,effectively alleviating edema symptoms and improving upper limb function with high safety.Its mechanism may relate to traditional Chinese medicine principles of“unblocking meridians,promoting blood circulation,and resolving stasis”and modern medical concepts of“enhancing local blood circulation,facilitating lymphatic drainage,and reducing inflammatory responses”.展开更多
Here we report on simultaneous lidar observations of sporadic Ni(Nis)layers and sporadic Na(Nas)layers in the atmosphere over Yanqing,Beijing(40.42°N,116.02°E)from April 2019 to October 2022.During 343 night...Here we report on simultaneous lidar observations of sporadic Ni(Nis)layers and sporadic Na(Nas)layers in the atmosphere over Yanqing,Beijing(40.42°N,116.02°E)from April 2019 to October 2022.During 343 nights of observation,68 Nis and 56 Nas were observed.The seasonal variation of Nis and Nas was also obtained,with the highest occurrence of Nis being in July(43%)and that of Nas being in June(61%).We found that the seasonal variation of Nis is similar to that of Nas and that both occur more frequently in summer than in winter.In addition,we found 23 events in which Nis and Nas occur simultaneously.The average peak altitude of Nas is approximately 1 km higher than that of Nis,and the peak density ratio of Nas to Nis is approximately 5,which is half the density ratio of the two main layers.Additionally,the strength factor for Nas is smaller than that for Nis.Through data analysis of sporadic E layers(Es),we found that Nis and Nas has a significant correlation with Es.The neutralization rates of Ni^(+)/Na^(+)were calculated according to the dissociative recombination reaction of Ni^(+)/Na^(+)and the WACCM-Ni(Whole Atmosphere Community Climate Model of Ni).The production rates of Ni and Na were estimated to be approximately 1:4.4,which is consistent with the density ratio of Nis to Nas.The results showed that the neutralization reaction of Ni+,Na+,and electrons in Es is the main reason for the formation of the Nis layer and the Nas layer.展开更多
Lithium metal batteries(LMBs)represent a promising solution for next-generation energy storage due to their high energy density,but the growth of lithium dendrites presents significant challenges to their performance ...Lithium metal batteries(LMBs)represent a promising solution for next-generation energy storage due to their high energy density,but the growth of lithium dendrites presents significant challenges to their performance and safety.This review provides a comprehensive overview of the mechanisms behind lithium dendrite formation and the role of in situ/operando observation and phase field simulation in understanding and mitigating this issue,The key driving factors of dendrite growth,such as lithium-ion flux heterogeneity,surface defects,and localized stress,are explored through advanced experimental techniques,which enable real-time visualization of dendrite nucleation and growth dynamics.Complementarily,phase field simulations provide insights into subsurface and temporal evolution of dendrites by modeling thermodynamic and kinetic processes,while machine learning techniques optimize simulation accuracy through data-driven parameter refinement.The integration of experimental observations with simulation models holds great potential in improving understanding and predictive capabilities.Despite ongoing progress,challenges remain in resolving technical limitations in observation techniques,improving computational efficiency,and fostering interdisciplinary collaboration.This review highlights the synergy between experimental and computational strategies in advancing the development of LMBs and calls for continued research to overcome existing hurdles and unlock the full potential of lithium metal anodes.展开更多
The spatial variability in the atmospheric CO_(2)and CH_(4)concentrations in urban land is affected by the source type,source distribution,and emission intensity in the cityscape.In this study,we analyzed vehicle-moun...The spatial variability in the atmospheric CO_(2)and CH_(4)concentrations in urban land is affected by the source type,source distribution,and emission intensity in the cityscape.In this study,we analyzed vehicle-mounted measurements of street-level CO_(2)and CH_(4)concentrations in Hangzhou—a large metropolitan area in the Yangtze River Delta in eastern China.The results revealed that CO_(2)and CH_(4)emission hotspots did not overlap geographically,with the former occurring as linear features at elevated road intersections and expressways and the latter occurring at waste treatment facilities(sewage treatment plants and landfills).The CH_(4):CO_(2)emission ratios(ppb ppm^(-1))were ranked in increasing order as follows:traffic(1.01±1.82;mean±1 SD);overall(3.46±2.71);sewage treatment(12.76±2.50);and landfill(36.50±10.15).Waste treatment was largely responsible for the increased overall emission ratio,supporting this source category as a major contributor to the CH_(4)budget in this city and suggesting a negligible role of domestic appliances(cookstoves and water heaters).A two-source mixing model calculation indicated that 99.9%of nonelectric vehicles in Hangzhou were gasoline-powered,revealing a recent shift in vehicle fuel composition from gasoline/natural gas to gasoline/electricity.The methodology established in this study is applicable to cities elsewhere.展开更多
BACKGROUND Colonic diverticular bleeding(CDB)is a leading cause of gastrointestinal blee-ding-related hospitalizations in Japan and is increasingly recognized as a signifi-cant burden in the United States.Identifying ...BACKGROUND Colonic diverticular bleeding(CDB)is a leading cause of gastrointestinal blee-ding-related hospitalizations in Japan and is increasingly recognized as a signifi-cant burden in the United States.Identifying the stigmata of a recent hemorrhage(SRH)during colonoscopy enables targeted hemostasis and reduces rebleeding.However,no benchmark exists for an appropriate observation duration,resulting in operator-dependent variation.Short observation periods may lead to missed SRH,whereas unnecessarily prolonged procedures,particularly in older patients,can increase patient burden and limit endoscopy unit availability.METHODS We retrospectively analyzed patients with acute hematochezia who underwent an initial colonoscopy between January 2017 and December 2024 at a Japanese tertiary hospital.The Observation time was measured from scope insertion to SRH detection(excluding therapeutic time)or withdrawal.The primary outcome,the“5%plateau time”,was defined as the point when the proportion of patients newly identified with SRH in each 5-minute interval consistently dropped below 5%.Computed tomography(CT)-based stratified analyses were performed by endoscopists who conducted≥10%of procedures.RESULTS Of the 1039 patients who underwent colonoscopy,845(mean age 77±11 years;64.5%male)were included.Nine board-certified endoscopists performed the procedures.SRH was detected in 286 patients(33.8%),with a median detection time of 19 minutes(interquartile range,12-28 minutes).The overall 5%plateau time was 40 minutes and varied according to the CT findings:40,35,and 30 minutes for no extravasation,right-sided extravasation,and left-sided extravasation,respectively.This time point corresponded to when 80%-90%of SRH cases were detected.De-spite variations in SRH detection rates and observation durations among endoscopists,the 5%plateau time was consistently approximately 40 minutes.CONCLUSION Although it varied according to the CT findings,the overall 5%plateau time was 40 minutes.This offers a practical benchmark for the minimum observation time without SRH detection.展开更多
Micro-nano Earth Observation Satellite(MEOS)constellation has the advantages of low construction cost,short revisit cycle,and high functional density,which is considered a promising solution for serving rapidly growin...Micro-nano Earth Observation Satellite(MEOS)constellation has the advantages of low construction cost,short revisit cycle,and high functional density,which is considered a promising solution for serving rapidly growing observation demands.The observation Scheduling Problem in the MEOS constellation(MEOSSP)is a challenging issue due to the large number of satellites and tasks,as well as complex observation constraints.To address the large-scale and complicated MEOSSP,we develop a Two-Stage Scheduling Algorithm based on the Pointer Network with Attention mechanism(TSSA-PNA).In TSSA-PNA,the MEOS observation scheduling is decomposed into a task allocation stage and a single-MEOS scheduling stage.In the task allocation stage,an adaptive task allocation algorithm with four problem-specific allocation operators is proposed to reallocate the unscheduled tasks to new MEOSs.Regarding the single-MEOS scheduling stage,we design a pointer network based on the encoder-decoder architecture to learn the optimal singleMEOS scheduling solution and introduce the attention mechanism into the encoder to improve the learning efficiency.The Pointer Network with Attention mechanism(PNA)can generate the single-MEOS scheduling solution quickly in an end-to-end manner.These two decomposed stages are performed iteratively to search for the solution with high profit.A greedy local search algorithm is developed to improve the profits further.The performance of the PNA and TSSA-PNA on singleMEOS and multi-MEOS scheduling problems are evaluated in the experiments.The experimental results demonstrate that PNA can obtain the approximate solution for the single-MEOS scheduling problem in a short time.Besides,the TSSA-PNA can achieve higher observation profits than the existing scheduling algorithms within the acceptable computational time for the large-scale MEOS scheduling problem.展开更多
This study explored the observation strategy and effectiveness of synoptic-scale adaptive observations for improving sea fog prediction in coastal regions around the Bohai Sea based on a poorly predicted fog event wit...This study explored the observation strategy and effectiveness of synoptic-scale adaptive observations for improving sea fog prediction in coastal regions around the Bohai Sea based on a poorly predicted fog event with cold-front synoptic pattern(CFSP).An ensemble Kalman filter data assimilation system for the Weather Research and Forecasting model was adopted with ensemble sensitivity analysis(ESA).By comparing observation impacts(estimated from a 40-member ensemble with ESA)among different meteorological observation variables and pressure levels,the temperature at 850 hPa and surface layer(850 hPa-and-surface temperature)was selected as the target observation type.Additionally,the area with large observation impacts for this observation type was predicted in the transition region of the surface low–high system.This area developed southward with the low and moved eastward with the low–high system,which could be explained by the main features of CFSP.Moreover,both experiments assimilating synthetic and real observations showed that assimilating 850 hPa-and-surface temperature observations generally yielded better fog coverage forecasts in areas with greater observation impacts than areas with smaller impacts.However,the effectiveness of adaptive observations was reduced when real observations rather than synthetic observations were assimilated,which is possibly due to factors such as observation and model errors.The main conclusions above were verified by another typical fog event with CFSP characteristics.Results of this study highlight the importance of improved initial conditions in the transition region of the low–high system for improving fog prediction and provide scientific guidance for implementing an observation network for fog forecasting over the Bohai Sea.展开更多
The characteristics of nonmetallic inclusions formed during steel production have a significant influence on steel performance.In this paper,studies on inclusions using confocal scanning laser microscopy(CSLM)are revi...The characteristics of nonmetallic inclusions formed during steel production have a significant influence on steel performance.In this paper,studies on inclusions using confocal scanning laser microscopy(CSLM)are reviewed and summarized,particularly the col-lision of various inclusions,dissolution of inclusions in liquid slag,and reactions between inclusions and steel.Solid inclusions exhibited a high collision tendency,whereas pure liquid inclusions exhibited minimal collisions because of the small attraction force induced by their<90°contact angle with molten steel.The collision of complex inclusions in molten steel was not included in the scope of this study and should be evaluated in future studies.Higher CaO/Al_(2)O_(3)and CaO/SiO_(2)ratios in liquid slag promoted the dissolution of Al_(2)O_(3)-based in-clusions.The formation of solid phases in the slag should be prevented to improve dissolution of inclusions.To accurately simulate the dissolution of inclusions in liquid slag,in-situ observation of the dissolution of inclusions at the steel-slag interface is necessary.Using a combination of CSLM and scanning electron microscopy-energy dispersive spectroscopy,the composition and morphological evolution of the inclusions during their modification by the dissolved elements in steel were observed and analyzed.Although the in-situ observa-tion of MnS and TiN precipitations has been widely studied,the in-situ observation of the evolution of oxide inclusions in steel during so-lidification and heating processes has rarely been reported.The effects of temperature,heating and cooling rates,and inclusion character-istics on the formation of acicular ferrites(AFs)have been widely studied.At a cooling rate of 3-5 K/s,the order of AF growth rate in-duced by different inclusions,as reported in literature,is Ti-O<Ti-Ca-Zr-Al-O<Mg-O<Ti-Zr-Al-O<Mn-Ti-Al-O<Ti-Al-O<Zr-Ti-Al-O.Further comprehensive experiments are required to investigate the quantitative relationship between the formation of AFs and inclusions.展开更多
The high-temperature dissolution behavior of primary carbides in samples taken from GCr15 continuous-casting bloom was observed in-situ by confocal laser scanning microscopy.Equations were fitted to the dissolution ki...The high-temperature dissolution behavior of primary carbides in samples taken from GCr15 continuous-casting bloom was observed in-situ by confocal laser scanning microscopy.Equations were fitted to the dissolution kinetics of primary carbides during either heating or soaking.Dissolution of carbides proceeded in three stages(fast→slow→faster)as either temperature or holding time was increased.During the heating process and during the first and third stages of the soaking process,the original size of the carbides determined the steepness of the slope,but during the middle(“slow”)stage of the soaking process,the slope remained zero.The initial size of the carbides varied greatly,but their final dissolution temperature fell within the narrow range of 1210-1235℃,and the holding time remained within 50 min.Fractal analysis was used to study the morphological characteristics of small and medium-sized carbides during the dissolution process.According to changes in the fractal dimension before and after soaking,the carbides tended to evolve towards a more regular morphology.展开更多
OBJECTIVE:To explore the clinical observation of white eye distribution characteristics of hyperlipidemic patients based on artificial intelligence digital eye diagnosis technology.METHODS:One hundred and fifty subjec...OBJECTIVE:To explore the clinical observation of white eye distribution characteristics of hyperlipidemic patients based on artificial intelligence digital eye diagnosis technology.METHODS:One hundred and fifty subjects were examined in the outpatient and inpatient departments of Guang'anmen Hospital of the China Academy of Traditional Chinese Medicine from 01 February 2022 to 01 February 2023,including 80 cases in the hyperlipidemic patient(HLP)group and 70 cases in the normal lipid level patient(NC)group.The two groups were collected and extracted by the artificial intelligence visual diagnostic instrument and analyzed by the MyEyeD-10 white eye shadowless imaging health intelligence analysis system.Finally,SPSS 26.0(Version X;IBM Corp.,Armonk,NY,USA)was used for statistical processing.RESULTS:Significant differences were noted in the scores of"spot"and"foggy"features between the two groups.Between groups,the"spot"feature score of the white eye morphology in the HLP group(11.07±3.22)was higher than that in the NC group(7.50±4.11)(P<0.01).Moreover,the"foggy"feature score of the eye morphology in the HLP group(8.37±2.25)was higher than that in the NC group(P<0.01),higher than that of the NC group(5.72±1.21)(P<0.05).There were significant differences in the"A"(stomach),"B","O"(spleen),and"M"(liver)eye-contact region scores between the two groups,and the"B","O"(spleen)and"M"(liver)eye-contact region scores were significantly different.The scores of the white eye channel region in the HLP group were significantly higher than those in the control group,with the"A","B",and"O"regions(P<0.01),"M"region(P<0.01),"A","B","O",and"M"region(P<0.01)."M"zone(P<0.05).The scores of"dull red"and"yellow"features were significantly different,and the scores of"dull red"and"yellow"colors of the white eye choroid in the HLP group were significantly higher than those in the HLP group.The scores of"dull red"and"yellow"were significantly higher in the HLP group than in the NC group(P<0.01).CONCLUSION:The morphological features of the white eye ocular image,the white eye chakra's color,and the bulbar conjunctiva's vascular zoning are closely related to hyperlipidemia.Importantly,these provide a reference for the objectivity and precision of the identification of Chinese medicine by looking at the eyes.展开更多
The Macao satellites differ from their predecessors in their orbits:MSS-1(Macao Science Satellite-1)is in low inclination and the planned MSS-2 will be in highly elliptical orbits.This paper reviews the fundamental ad...The Macao satellites differ from their predecessors in their orbits:MSS-1(Macao Science Satellite-1)is in low inclination and the planned MSS-2 will be in highly elliptical orbits.This paper reviews the fundamental advantages and disadvantages of the different possible magnetic measurements:the component(declination,intensity,etc.)and location(satellite,ground,etc.).When planning a survey the choice of component is the"What?"question;the choice of location the"Where?"question.Results from potential theory inform the choice of measurement and data analysis.For example,knowing the vertical component of magnetic field provides a solution for the full magnetic field everywhere in the potential region.This is the familiar Neumann problem.In reality this ideal dataset is never available.In the past we were restricted to declination data only,then direction only,then total intensity only.There have also been large swathes of Earth's surface with no measurements at all(MSS-1 is restricted to latitudes below).These incomplete datasets throw up new questions for potential theory,questions that have some intriguing answers.When only declination is known uniqueness is provided by horizontal intensity measurements on a single line joining the dip-poles.When only directions are involved uniqueness is provided by a single intensity measurement,at least in principle.Paleomagnetic intensities can help.When only total intensity is known,as was largely the case in the early satellite era,uniqueness is provided by a precise location of the magnetic equator.Holes in the data distribution is a familiar problem in geophysical studies.All magnetic measurements sample,to a greater or lesser extent,the potential field everywhere.There is a trade-off between measurements close to the source,good for small targets and high resolution,and the broader sample of a distant measurement.The sampling of a measurement is given by the appropriate Green's function of the Laplacian,which determines both the resolution and scope of the measurement.For example,radial and horizontal measurements near the Earth's surface give a weighted average of the radial component over a patch of the core surface beneath the measurement site about in radius.The patch is smaller for shallower surfaces,for example from satellite to ground.Holes in the data distribution do not correspond to similar holes at the source surface;the price paid is in resolution of the source.I argue that,in the past,we have been too reluctant to take advantage of incomplete and apparently hopeless datasets.展开更多
Adaptive optics(AO)has significantly advanced high-resolution solar observations by mitigating atmospheric turbulence.However,traditional post-focal AO systems suffer from external configurations that introduce excess...Adaptive optics(AO)has significantly advanced high-resolution solar observations by mitigating atmospheric turbulence.However,traditional post-focal AO systems suffer from external configurations that introduce excessive optical surfaces,reduced light throughput,and instrumental polarization.To address these limitations,we propose an embedded solar adaptive optics telescope(ESAOT)that intrinsically incorporates the solar AO(SAO)subsystem within the telescope's optical train,featuring a co-designed correction chain with a single Hartmann-Shack full-wavefront sensor(HS f-WFS)and a deformable secondary mirror(DSM).The HS f-WFS uses temporal-spatial hybrid sampling technique to simultane-ously resolve tip-tilt and high-order aberrations,while the DSM performs real-time compensation through adaptive modal optimization.This unified architecture achieves symmetrical polarization suppression and high system throughput by min-imizing optical surfaces.A 600 mm ESAOT prototype incorporating a 12×12 micro-lens array HS f-WFS and 61-actuator piezoelectric DSM has been developed and successfully conducted on-sky photospheric observations.Validations in-cluding turbulence simulations,optical bench testing,and practical observations at the Lijiang observatory collectively confirm the system's capability to maintain aboutλ/10 wavefront error during active region tracking.This architectural breakthrough of the ESAOT addresses long-standing SAO integration challenges in solar astronomy and provides scala-bility analyses confirming direct applicability to the existing and future large solar observation facilities.展开更多
This paper explores how traditional Chinese medicine(TCM),in the absence of modern medical instruments,employed observation and perception to understand and diagnose malignant tumors(cancer).It also reviews the evolut...This paper explores how traditional Chinese medicine(TCM),in the absence of modern medical instruments,employed observation and perception to understand and diagnose malignant tumors(cancer).It also reviews the evolution of relevant knowledge and treatment approaches since the introduction of Western medical technology.In ancient times,TCM primarily relied on external symptoms,palpation,and patient-reported experiences to infer internal masses,with a focus on gynecological disorders.Ancient TCM practitioners deduced internal conditions through patterns such as menstrual irregularities,abdominal masses,and abnormal discharges.Early descriptions of malignant tumors employed the character“癌(cancer)”to symbolize rock-like cavities,yet the descriptions were chiefly limited to external manifestations,with limited understanding of internal pathology.With the introduction of Western medicine,Chinese society gradually expanded its comprehension of cancer and adopted surgical as well as other therapies.In contrast,modern TCM has increasingly emphasized its own therapeutic effects,even promoting claims of cancer cure,warranting further investigation.The paper highlights the transition in TCM from a diagnostic model based mainly on observation and perception to another model increasingly combined with modern imaging and laboratory techniques.The transition underscores the need for innovation in TCM’s future development,while also revealing the diagnostic experience of ancient practice.Understanding TCM’s historical recognition of malignant tumors from the perspective of history of medicine may provide insights for contemporary TCM approaches to cancer treatment.展开更多
Fractures play a crucial role in various fields such as hydrocarbon exploration,groundwater resources management,and earthquake research.The determination of fracture location and the estimation of parameters such as ...Fractures play a crucial role in various fields such as hydrocarbon exploration,groundwater resources management,and earthquake research.The determination of fracture location and the estimation of parameters such as fracture length and dip angle are the focus of geophysical work.In borehole observation system,the short distance between fractures and detectors leads to weak attenuation of elastic wave energy,and high-frequency source makes it easier to identify small-scale fractures.Compared to traditional monopole logging methods,dipole logging method has advantage of exciting pure shear waves sensitive to fractures,so its application is becoming increasingly widespread.However,since the reflected shear waves and scattered shear waves of fractures correspond to different fracture properties,how to distinguish and analyze these two kinds of waves is crucial for accurately characterizing the fracture parameters.To address this issue,numerical simulation of wave responses by a single fracture near a borehole in rock formation is performed,and the generation mechanism and characteristics of shear waves scattered by fractures are investigated.It is found that when the dip angle of the fracture surpasses a critical threshold,the S-wave will propagate to both endpoints of the fracture and generate scattered S-waves,resulting in two distinct scattered wave packets on the received waveform.When the polarization direction of the acoustic source is parallel to the strike of the fracture,the scattered SH-waves always have larger amplitude than the scattered SV-waves regardless of changing the fracture dip angle.Unlike SV-waves,the SH-waves scattered by the fracture do not have any mode conversion.Additionally,propagation of S-waves to a short length fracture can induce dipole mode vibration of the fracture within a wide frequency range.The phenomena of shear waves reflected and scattered by the fracture are further illustrated and verified by two field examples,thus showing the potential of scattered waves for fracture evaluation and characterization with borehole observation system.展开更多
Spectral imaging for Earth observation^([1])is an advanced interdisciplinary research field at the forefront of remote sensing,geoscience,and information technology.It continues to develop and make breakthroughs in th...Spectral imaging for Earth observation^([1])is an advanced interdisciplinary research field at the forefront of remote sensing,geoscience,and information technology.It continues to develop and make breakthroughs in theoretical development,technological innovation,and industrial applications.In the era of rapid development in artificial intelligence and spectral imaging technology,the acquisition and processing of remote sensing information have become more intelligent.展开更多
Air-sea water vapor and CO_(2) flux observation experiments were carried out at the Yantai National Satellite Ocean Calibration Platform and the jetty at Monolithic Beach,Juehua Island,using a 100 Hz gas analyzer.The ...Air-sea water vapor and CO_(2) flux observation experiments were carried out at the Yantai National Satellite Ocean Calibration Platform and the jetty at Monolithic Beach,Juehua Island,using a 100 Hz gas analyzer.The observations were corrected by employing wild point rejection,linear detrending,delay correction,coordinate rotation,time matching,and Webb,Pearman,and Leuning(WPL)correction.The results of spectral analysis and a turbulence development adequacy data quality check showed that the overall observation data quality was good.The air-sea water vapor and CO_(2) flux results showed that the observation duration affected both the air-sea flux intensity and direction at different observation frequencies.At shorter observation durations,the air-sea flux values measured at 100 Hz were smaller than the 20 Hz measurements and had opposite directions.In addition,the WPL correction reduced the overall air-sea flux and partially minimized the effect of observation frequency on the air-sea flux intensity.These results showed that high-frequency observations showed more turbulence variations than low-frequency observations.This conclusion could promote an understanding of small-scale turbulence variations.展开更多
基金supported by the Operation,Maintenance and Upgrading Fund for Astronomical Telescopes and Facility Instruments,budgeted by the Ministry of Finance of China(MOF)and administered by the Chinese Academy of Sciences(CAS),the National Natural Science Foundation of China(Nos.12173093 and 11973094)a science research grant from the China Manned Space Project(No.CMS-CSST-2021-B08).
文摘The Antarctic Tianmu Staring Observation Project(ATSOP)entails the deployment of 30 small-aperture,wide-field optical telescopes in the Antarctic region.The system will perform long-term continuous observation campaigns over a period of 100 d(24 h per day)per year,as well as short-time-scale sampling at intervals of 5 min,across a sky area of approximately 1200 square degrees centered near the south celestial pole.We have assessed the types of small solar system bodies detectable by the ATSOP telescopes,as well as the associated scientific research opportunities.Our analysis indicates that the ATSOP is capable of detecting near-Earth objects(NEOs)with all orbital inclinations,as well as high-inclination small bodies located beyond the main asteroid belt.Potential research topics include the discovery and identification of small bodies,orbit determination,physical characterization,investigation into the activity characteristics and evolutionary patterns of active small bodies,and studies on their dynamical evolution.Observations of NEOs can also contribute to planetary defense efforts.On the basis of pilot observational data collected by the Antarctic Tianmu prototype(AT-Proto)between February 20 and October 26,2023,a total of 478 asteroids and 9 comets were successfully identified,demonstrating the effectiveness of the ATSOP system in observing small solar system bodies.Looking ahead,with anticipated performance enhancements in the second-generation AT-Proto,the limiting magnitude will increase from 16 to 18,thereby enabling the detection of an even greater number of small solar system bodies.
文摘State Field Observation and Research Station of Debris Flow in Dongchuan,Yunnan is also named Dongchuan Debris Flow Observation and Research Station,Chinese Academy of Sciences.The study area,Jiangjia Ravine,is about 48.6 km2 and characterized by intense tectonism.Accumulated clastic detritus is the main source of the materials in the debris flows when an intense rainfall occurs.The recorded highest density and sediment transport are 2370 kg/m^(3) and 6.079×10^(6) kg/s,respectively.The ravine is now called the“debris flow museum”in China and supplies advantageous research conditions.
文摘Climate change,natural disasters,pollution,and fast urbanization have made environmental security a more serious international issue.Timely,accurate,and multi-dimensional information is essential in the effective monitoring and management of such complex challenges in the environment.The Earth Observation(EO)systems,including optical sensors,radar sensors,Light Detection and Ranging(LiDAR)sensors,thermal sensors,Unmanned Aerial Vehicle(UAV)sensors,and in-situ sensors,offer a good coverage of space and time,as well as provide useful information on land,water,and atmospheric processes.But the shortcomings or weaknesses of individual sensors,such as their vulnerability to weather conditions,spectral or spatial resolution,and gaps in time,can tend to limit their ability to provide a complete picture of the environment.One of the solutions has been multi-sensor fusion,which combines heterogeneous data and makes it more accurate,robust,and interpretable.This systematic review analyzes the latest methods of multi-sensor fusion,which are machine learning,deep learning,probabilistic models,and hybrid approaches,in terms of methodological principles,preprocessing needs,and computational frameworks.Applications in environmental security are highlighted,which include monitoring natural disasters,monitoring of climate and ecosystem,pollution monitoring,monitoring of land use change,and early warning systems.The review also covers evaluation measures,validation plans,and uncertainty measures,where a strict measure of evaluation is vital to making actionable decisions.Lastly,emerging issues,e.g.,data heterogeneity,computational needs,sensor interoperability,and prospects in the future,e.g.,AI-based adaptive fusion,UAVs and Internet of Things(IoT)integration,and scalable cloud-based systems,are discussed.The synthesis has highlighted the transformational capability of multi-sensor EO in terms of improving the environment in the context of environmental security and sustainable management.
基金supported by the National Key R&D Plan Program of China [Grant number 2021YFC3101500]the National Natural Science Foundation of China [Grant number 42305014,42506024]。
文摘Energy transfers among internal waves in the northern South China Sea are not well characterized,particularly during typhoons,owing to the lack of in situ observations.Based on high-resolution mooring data collected during Typhoon Trami(2024),this study reveals the occurrence of robust vertical energy redistribution among diurnal internal tides(D1 ITs)and near-inertial waves(NIWs).Strikingly,the typhoon not only amplified the NIW energy but also triggered an unexpected surge in the D1 IT energy.The observed average net energy transfer rate of 1×10^(-7) W kg^(−1) from typhoon-forced NIWs to D1 ITs occurred at water depths of 120-170 m.Further bispectral analysis indicated that the energy transfer is driven by nonlinear wave—wave interaction.These results reveal the existence of a new energy transfer pathway—from atmospheric forcing to D1 ITs—and redefine the redistribution of the internal wave energy during extreme weather events.
文摘Objective:To evaluate the clinical efficacy of blood-letting cupping combined with manual lymphatic drainage in treating breast cancer-related lymphedema(BCRL)and explore its mechanism of action from both traditional Chinese medicine and modern medical perspectives,providing a scientific basis and novel therapeutic approaches for clinical management of BCRL.Methods:Patients with BCRL admitted to the outpatient and inpatient departments of Hebei University Affiliated Hospital were enrolled.A prospective randomized controlled trial design was adopted,with eligible patients randomly assigned to a treatment group and a control group.The control group received manual lymphatic drainage alone,while the treatment group received manual lymphtic drainage combined with blood-letting cupping therapy.Posttreatment comparisons evaluated upper limb circumference reduction,edema severity grading,and upper limb functional scores.Vital signs and adverse reactions during treatment were recorded for both groups.Statistical software analyzed the data.Results:The treatment group demonstrated significantly greater reduction in upper limb circumference,improvement in edema severity,and higher upper limb function scores compared to the control group(P<0.05).Vital signs remained stable throughout treatment in both groups.No severe adverse reactions occurred in the treatment group;only isolated cases of mild skin itching were reported,which resolved after symptomatic management.Conclusion:The combination of bloodletting cupping and manual lymphatic drainage demonstrates reliable efficacy in treating BCRL,effectively alleviating edema symptoms and improving upper limb function with high safety.Its mechanism may relate to traditional Chinese medicine principles of“unblocking meridians,promoting blood circulation,and resolving stasis”and modern medical concepts of“enhancing local blood circulation,facilitating lymphatic drainage,and reducing inflammatory responses”.
基金supported by the Specialized Research Fund for State Key Laboratories,Chinese Meridian Project,the Specialized Research Fund for the State Key Laboratory of Solar Activity and Space Weather,postgraduate Education Reform and Quality Improvement Project of Henan Province(Grant No.YJS2024JD32)Natural Science Foundation Project of Henan Province(Grant No.242300420253)National Natural Science Foundation of China for Young Scientists(Grant No.42504156)funding.
文摘Here we report on simultaneous lidar observations of sporadic Ni(Nis)layers and sporadic Na(Nas)layers in the atmosphere over Yanqing,Beijing(40.42°N,116.02°E)from April 2019 to October 2022.During 343 nights of observation,68 Nis and 56 Nas were observed.The seasonal variation of Nis and Nas was also obtained,with the highest occurrence of Nis being in July(43%)and that of Nas being in June(61%).We found that the seasonal variation of Nis is similar to that of Nas and that both occur more frequently in summer than in winter.In addition,we found 23 events in which Nis and Nas occur simultaneously.The average peak altitude of Nas is approximately 1 km higher than that of Nis,and the peak density ratio of Nas to Nis is approximately 5,which is half the density ratio of the two main layers.Additionally,the strength factor for Nas is smaller than that for Nis.Through data analysis of sporadic E layers(Es),we found that Nis and Nas has a significant correlation with Es.The neutralization rates of Ni^(+)/Na^(+)were calculated according to the dissociative recombination reaction of Ni^(+)/Na^(+)and the WACCM-Ni(Whole Atmosphere Community Climate Model of Ni).The production rates of Ni and Na were estimated to be approximately 1:4.4,which is consistent with the density ratio of Nis to Nas.The results showed that the neutralization reaction of Ni+,Na+,and electrons in Es is the main reason for the formation of the Nis layer and the Nas layer.
基金the financial support of the National Natural Science Foundation of China(Nos.12172206 and 11972218)。
文摘Lithium metal batteries(LMBs)represent a promising solution for next-generation energy storage due to their high energy density,but the growth of lithium dendrites presents significant challenges to their performance and safety.This review provides a comprehensive overview of the mechanisms behind lithium dendrite formation and the role of in situ/operando observation and phase field simulation in understanding and mitigating this issue,The key driving factors of dendrite growth,such as lithium-ion flux heterogeneity,surface defects,and localized stress,are explored through advanced experimental techniques,which enable real-time visualization of dendrite nucleation and growth dynamics.Complementarily,phase field simulations provide insights into subsurface and temporal evolution of dendrites by modeling thermodynamic and kinetic processes,while machine learning techniques optimize simulation accuracy through data-driven parameter refinement.The integration of experimental observations with simulation models holds great potential in improving understanding and predictive capabilities.Despite ongoing progress,challenges remain in resolving technical limitations in observation techniques,improving computational efficiency,and fostering interdisciplinary collaboration.This review highlights the synergy between experimental and computational strategies in advancing the development of LMBs and calls for continued research to overcome existing hurdles and unlock the full potential of lithium metal anodes.
基金supported by the National Natural Science Foundation of China(Grant Nos.U24A20590,42021004)the Joint funds of the Zhejiang Provincial Natural Science Foundation of China(GrantNo.LZJMZ23D050002)+2 种基金the 333 Project of Jiangsu Province(Grant No.BRA2022023)the Natural Science Foundation of Jiangsu Province for Distinguished Young Scholars(Grant No.BK20220055)the Key Laboratory of Ecosystem Carbon Source and Sink,China Meteorological Administration(Grant No.ECSS-CMA202302)。
文摘The spatial variability in the atmospheric CO_(2)and CH_(4)concentrations in urban land is affected by the source type,source distribution,and emission intensity in the cityscape.In this study,we analyzed vehicle-mounted measurements of street-level CO_(2)and CH_(4)concentrations in Hangzhou—a large metropolitan area in the Yangtze River Delta in eastern China.The results revealed that CO_(2)and CH_(4)emission hotspots did not overlap geographically,with the former occurring as linear features at elevated road intersections and expressways and the latter occurring at waste treatment facilities(sewage treatment plants and landfills).The CH_(4):CO_(2)emission ratios(ppb ppm^(-1))were ranked in increasing order as follows:traffic(1.01±1.82;mean±1 SD);overall(3.46±2.71);sewage treatment(12.76±2.50);and landfill(36.50±10.15).Waste treatment was largely responsible for the increased overall emission ratio,supporting this source category as a major contributor to the CH_(4)budget in this city and suggesting a negligible role of domestic appliances(cookstoves and water heaters).A two-source mixing model calculation indicated that 99.9%of nonelectric vehicles in Hangzhou were gasoline-powered,revealing a recent shift in vehicle fuel composition from gasoline/natural gas to gasoline/electricity.The methodology established in this study is applicable to cities elsewhere.
文摘BACKGROUND Colonic diverticular bleeding(CDB)is a leading cause of gastrointestinal blee-ding-related hospitalizations in Japan and is increasingly recognized as a signifi-cant burden in the United States.Identifying the stigmata of a recent hemorrhage(SRH)during colonoscopy enables targeted hemostasis and reduces rebleeding.However,no benchmark exists for an appropriate observation duration,resulting in operator-dependent variation.Short observation periods may lead to missed SRH,whereas unnecessarily prolonged procedures,particularly in older patients,can increase patient burden and limit endoscopy unit availability.METHODS We retrospectively analyzed patients with acute hematochezia who underwent an initial colonoscopy between January 2017 and December 2024 at a Japanese tertiary hospital.The Observation time was measured from scope insertion to SRH detection(excluding therapeutic time)or withdrawal.The primary outcome,the“5%plateau time”,was defined as the point when the proportion of patients newly identified with SRH in each 5-minute interval consistently dropped below 5%.Computed tomography(CT)-based stratified analyses were performed by endoscopists who conducted≥10%of procedures.RESULTS Of the 1039 patients who underwent colonoscopy,845(mean age 77±11 years;64.5%male)were included.Nine board-certified endoscopists performed the procedures.SRH was detected in 286 patients(33.8%),with a median detection time of 19 minutes(interquartile range,12-28 minutes).The overall 5%plateau time was 40 minutes and varied according to the CT findings:40,35,and 30 minutes for no extravasation,right-sided extravasation,and left-sided extravasation,respectively.This time point corresponded to when 80%-90%of SRH cases were detected.De-spite variations in SRH detection rates and observation durations among endoscopists,the 5%plateau time was consistently approximately 40 minutes.CONCLUSION Although it varied according to the CT findings,the overall 5%plateau time was 40 minutes.This offers a practical benchmark for the minimum observation time without SRH detection.
基金supported by the National Natural Science Foundation of China(No.62101587)the National Funded Postdoctoral Researcher Program of China(No.GZC20233578)。
文摘Micro-nano Earth Observation Satellite(MEOS)constellation has the advantages of low construction cost,short revisit cycle,and high functional density,which is considered a promising solution for serving rapidly growing observation demands.The observation Scheduling Problem in the MEOS constellation(MEOSSP)is a challenging issue due to the large number of satellites and tasks,as well as complex observation constraints.To address the large-scale and complicated MEOSSP,we develop a Two-Stage Scheduling Algorithm based on the Pointer Network with Attention mechanism(TSSA-PNA).In TSSA-PNA,the MEOS observation scheduling is decomposed into a task allocation stage and a single-MEOS scheduling stage.In the task allocation stage,an adaptive task allocation algorithm with four problem-specific allocation operators is proposed to reallocate the unscheduled tasks to new MEOSs.Regarding the single-MEOS scheduling stage,we design a pointer network based on the encoder-decoder architecture to learn the optimal singleMEOS scheduling solution and introduce the attention mechanism into the encoder to improve the learning efficiency.The Pointer Network with Attention mechanism(PNA)can generate the single-MEOS scheduling solution quickly in an end-to-end manner.These two decomposed stages are performed iteratively to search for the solution with high profit.A greedy local search algorithm is developed to improve the profits further.The performance of the PNA and TSSA-PNA on singleMEOS and multi-MEOS scheduling problems are evaluated in the experiments.The experimental results demonstrate that PNA can obtain the approximate solution for the single-MEOS scheduling problem in a short time.Besides,the TSSA-PNA can achieve higher observation profits than the existing scheduling algorithms within the acceptable computational time for the large-scale MEOS scheduling problem.
基金supported by the National Natural Science Foundation of China(Grant No.41705081)the Shandong Natural Science Foundation Project(Grant No.ZR2019ZD12)the Laoshan Laboratory(Grant No.LSKJ202202203).
文摘This study explored the observation strategy and effectiveness of synoptic-scale adaptive observations for improving sea fog prediction in coastal regions around the Bohai Sea based on a poorly predicted fog event with cold-front synoptic pattern(CFSP).An ensemble Kalman filter data assimilation system for the Weather Research and Forecasting model was adopted with ensemble sensitivity analysis(ESA).By comparing observation impacts(estimated from a 40-member ensemble with ESA)among different meteorological observation variables and pressure levels,the temperature at 850 hPa and surface layer(850 hPa-and-surface temperature)was selected as the target observation type.Additionally,the area with large observation impacts for this observation type was predicted in the transition region of the surface low–high system.This area developed southward with the low and moved eastward with the low–high system,which could be explained by the main features of CFSP.Moreover,both experiments assimilating synthetic and real observations showed that assimilating 850 hPa-and-surface temperature observations generally yielded better fog coverage forecasts in areas with greater observation impacts than areas with smaller impacts.However,the effectiveness of adaptive observations was reduced when real observations rather than synthetic observations were assimilated,which is possibly due to factors such as observation and model errors.The main conclusions above were verified by another typical fog event with CFSP characteristics.Results of this study highlight the importance of improved initial conditions in the transition region of the low–high system for improving fog prediction and provide scientific guidance for implementing an observation network for fog forecasting over the Bohai Sea.
基金supported by the National Key R&D Program(No.2023YFB3709900)the National Nature Science Foundation of China(No.U22A20171)+2 种基金China Baowu Low Carbon Metallurgy Innovation Foundation(No.BWLCF202315)the High Steel Center(HSC)at North China University of TechnologyUniversity of Science and Technology Beijing,China.
文摘The characteristics of nonmetallic inclusions formed during steel production have a significant influence on steel performance.In this paper,studies on inclusions using confocal scanning laser microscopy(CSLM)are reviewed and summarized,particularly the col-lision of various inclusions,dissolution of inclusions in liquid slag,and reactions between inclusions and steel.Solid inclusions exhibited a high collision tendency,whereas pure liquid inclusions exhibited minimal collisions because of the small attraction force induced by their<90°contact angle with molten steel.The collision of complex inclusions in molten steel was not included in the scope of this study and should be evaluated in future studies.Higher CaO/Al_(2)O_(3)and CaO/SiO_(2)ratios in liquid slag promoted the dissolution of Al_(2)O_(3)-based in-clusions.The formation of solid phases in the slag should be prevented to improve dissolution of inclusions.To accurately simulate the dissolution of inclusions in liquid slag,in-situ observation of the dissolution of inclusions at the steel-slag interface is necessary.Using a combination of CSLM and scanning electron microscopy-energy dispersive spectroscopy,the composition and morphological evolution of the inclusions during their modification by the dissolved elements in steel were observed and analyzed.Although the in-situ observa-tion of MnS and TiN precipitations has been widely studied,the in-situ observation of the evolution of oxide inclusions in steel during so-lidification and heating processes has rarely been reported.The effects of temperature,heating and cooling rates,and inclusion character-istics on the formation of acicular ferrites(AFs)have been widely studied.At a cooling rate of 3-5 K/s,the order of AF growth rate in-duced by different inclusions,as reported in literature,is Ti-O<Ti-Ca-Zr-Al-O<Mg-O<Ti-Zr-Al-O<Mn-Ti-Al-O<Ti-Al-O<Zr-Ti-Al-O.Further comprehensive experiments are required to investigate the quantitative relationship between the formation of AFs and inclusions.
基金supported by Independent Research Project of State Key Laboratory of Advanced Special Steel,Shanghai Key Laboratory of Advanced Ferrometallurgy,Shanghai University(SKLASS-2023-Z13)the Science and Technology Commission of Shanghai Municipality(No.19DZ2270200)+1 种基金A portion of the work was performed at US National High Magnetic Field Laboratory,which is supported by the National Science Foundation(Cooperative Agreement No.DMR-1157490 and DMR-1644779)the State of Florida.Thanks also to Mary Tyler for editing.
文摘The high-temperature dissolution behavior of primary carbides in samples taken from GCr15 continuous-casting bloom was observed in-situ by confocal laser scanning microscopy.Equations were fitted to the dissolution kinetics of primary carbides during either heating or soaking.Dissolution of carbides proceeded in three stages(fast→slow→faster)as either temperature or holding time was increased.During the heating process and during the first and third stages of the soaking process,the original size of the carbides determined the steepness of the slope,but during the middle(“slow”)stage of the soaking process,the slope remained zero.The initial size of the carbides varied greatly,but their final dissolution temperature fell within the narrow range of 1210-1235℃,and the holding time remained within 50 min.Fractal analysis was used to study the morphological characteristics of small and medium-sized carbides during the dissolution process.According to changes in the fractal dimension before and after soaking,the carbides tended to evolve towards a more regular morphology.
基金Supported by National Natural Science Foundation of China:Study on the Mechanism of Improving Cardiac Remodelling in Post-infarction Ischaemic Cardiomyopathy through lncRNA-Maternally Expressed Gene3/miR-223/Stromal Interaction Molecule 1 Calcium Signalling Axis by Activate Blood and Reassure Formula (No. 81973682)National Social Science Fund:Study on the Verification and Construction of the Theory System of Sanjiao Phase Fire and Yang Support Under the View of Civilisation Traceability (No. 21VJXG037)+1 种基金First Published:a Randomised Controlled Study of Fuyang Qiangxin Tang in the Treatment of Moderate to Severe Heart Failure (2024-1-4151)Project for Enhancing Clinical Research and Achievement Transformation Capabilities of High-Level Traditional Chinese Medicine Hospitals:Evaluation of the Efficacy and Preclinical Study of Fuyang Qiangxin Granules, a Traditional Chinese Medicine for Heart Failure (HLCMHPP2023045)
文摘OBJECTIVE:To explore the clinical observation of white eye distribution characteristics of hyperlipidemic patients based on artificial intelligence digital eye diagnosis technology.METHODS:One hundred and fifty subjects were examined in the outpatient and inpatient departments of Guang'anmen Hospital of the China Academy of Traditional Chinese Medicine from 01 February 2022 to 01 February 2023,including 80 cases in the hyperlipidemic patient(HLP)group and 70 cases in the normal lipid level patient(NC)group.The two groups were collected and extracted by the artificial intelligence visual diagnostic instrument and analyzed by the MyEyeD-10 white eye shadowless imaging health intelligence analysis system.Finally,SPSS 26.0(Version X;IBM Corp.,Armonk,NY,USA)was used for statistical processing.RESULTS:Significant differences were noted in the scores of"spot"and"foggy"features between the two groups.Between groups,the"spot"feature score of the white eye morphology in the HLP group(11.07±3.22)was higher than that in the NC group(7.50±4.11)(P<0.01).Moreover,the"foggy"feature score of the eye morphology in the HLP group(8.37±2.25)was higher than that in the NC group(P<0.01),higher than that of the NC group(5.72±1.21)(P<0.05).There were significant differences in the"A"(stomach),"B","O"(spleen),and"M"(liver)eye-contact region scores between the two groups,and the"B","O"(spleen)and"M"(liver)eye-contact region scores were significantly different.The scores of the white eye channel region in the HLP group were significantly higher than those in the control group,with the"A","B",and"O"regions(P<0.01),"M"region(P<0.01),"A","B","O",and"M"region(P<0.01)."M"zone(P<0.05).The scores of"dull red"and"yellow"features were significantly different,and the scores of"dull red"and"yellow"colors of the white eye choroid in the HLP group were significantly higher than those in the HLP group.The scores of"dull red"and"yellow"were significantly higher in the HLP group than in the NC group(P<0.01).CONCLUSION:The morphological features of the white eye ocular image,the white eye chakra's color,and the bulbar conjunctiva's vascular zoning are closely related to hyperlipidemia.Importantly,these provide a reference for the objectivity and precision of the identification of Chinese medicine by looking at the eyes.
文摘The Macao satellites differ from their predecessors in their orbits:MSS-1(Macao Science Satellite-1)is in low inclination and the planned MSS-2 will be in highly elliptical orbits.This paper reviews the fundamental advantages and disadvantages of the different possible magnetic measurements:the component(declination,intensity,etc.)and location(satellite,ground,etc.).When planning a survey the choice of component is the"What?"question;the choice of location the"Where?"question.Results from potential theory inform the choice of measurement and data analysis.For example,knowing the vertical component of magnetic field provides a solution for the full magnetic field everywhere in the potential region.This is the familiar Neumann problem.In reality this ideal dataset is never available.In the past we were restricted to declination data only,then direction only,then total intensity only.There have also been large swathes of Earth's surface with no measurements at all(MSS-1 is restricted to latitudes below).These incomplete datasets throw up new questions for potential theory,questions that have some intriguing answers.When only declination is known uniqueness is provided by horizontal intensity measurements on a single line joining the dip-poles.When only directions are involved uniqueness is provided by a single intensity measurement,at least in principle.Paleomagnetic intensities can help.When only total intensity is known,as was largely the case in the early satellite era,uniqueness is provided by a precise location of the magnetic equator.Holes in the data distribution is a familiar problem in geophysical studies.All magnetic measurements sample,to a greater or lesser extent,the potential field everywhere.There is a trade-off between measurements close to the source,good for small targets and high resolution,and the broader sample of a distant measurement.The sampling of a measurement is given by the appropriate Green's function of the Laplacian,which determines both the resolution and scope of the measurement.For example,radial and horizontal measurements near the Earth's surface give a weighted average of the radial component over a patch of the core surface beneath the measurement site about in radius.The patch is smaller for shallower surfaces,for example from satellite to ground.Holes in the data distribution do not correspond to similar holes at the source surface;the price paid is in resolution of the source.I argue that,in the past,we have been too reluctant to take advantage of incomplete and apparently hopeless datasets.
基金support from the National Science Foundation of China(NSFC)(Grants No.12293031 and No.61905252)the National Science Foundation for Distinguished Young Scholars(Grant No.12022308)the National Key R&D Program of China(Grants No.2021YFC2202200 and No.2021YFC2202204).
文摘Adaptive optics(AO)has significantly advanced high-resolution solar observations by mitigating atmospheric turbulence.However,traditional post-focal AO systems suffer from external configurations that introduce excessive optical surfaces,reduced light throughput,and instrumental polarization.To address these limitations,we propose an embedded solar adaptive optics telescope(ESAOT)that intrinsically incorporates the solar AO(SAO)subsystem within the telescope's optical train,featuring a co-designed correction chain with a single Hartmann-Shack full-wavefront sensor(HS f-WFS)and a deformable secondary mirror(DSM).The HS f-WFS uses temporal-spatial hybrid sampling technique to simultane-ously resolve tip-tilt and high-order aberrations,while the DSM performs real-time compensation through adaptive modal optimization.This unified architecture achieves symmetrical polarization suppression and high system throughput by min-imizing optical surfaces.A 600 mm ESAOT prototype incorporating a 12×12 micro-lens array HS f-WFS and 61-actuator piezoelectric DSM has been developed and successfully conducted on-sky photospheric observations.Validations in-cluding turbulence simulations,optical bench testing,and practical observations at the Lijiang observatory collectively confirm the system's capability to maintain aboutλ/10 wavefront error during active region tracking.This architectural breakthrough of the ESAOT addresses long-standing SAO integration challenges in solar astronomy and provides scala-bility analyses confirming direct applicability to the existing and future large solar observation facilities.
文摘This paper explores how traditional Chinese medicine(TCM),in the absence of modern medical instruments,employed observation and perception to understand and diagnose malignant tumors(cancer).It also reviews the evolution of relevant knowledge and treatment approaches since the introduction of Western medical technology.In ancient times,TCM primarily relied on external symptoms,palpation,and patient-reported experiences to infer internal masses,with a focus on gynecological disorders.Ancient TCM practitioners deduced internal conditions through patterns such as menstrual irregularities,abdominal masses,and abnormal discharges.Early descriptions of malignant tumors employed the character“癌(cancer)”to symbolize rock-like cavities,yet the descriptions were chiefly limited to external manifestations,with limited understanding of internal pathology.With the introduction of Western medicine,Chinese society gradually expanded its comprehension of cancer and adopted surgical as well as other therapies.In contrast,modern TCM has increasingly emphasized its own therapeutic effects,even promoting claims of cancer cure,warranting further investigation.The paper highlights the transition in TCM from a diagnostic model based mainly on observation and perception to another model increasingly combined with modern imaging and laboratory techniques.The transition underscores the need for innovation in TCM’s future development,while also revealing the diagnostic experience of ancient practice.Understanding TCM’s historical recognition of malignant tumors from the perspective of history of medicine may provide insights for contemporary TCM approaches to cancer treatment.
基金supported by Scientific Research and Technology Development Project of CNPC(2024ZG38,2024ZG42)the CNPC Innovation Fund(2022DQ02-0307).
文摘Fractures play a crucial role in various fields such as hydrocarbon exploration,groundwater resources management,and earthquake research.The determination of fracture location and the estimation of parameters such as fracture length and dip angle are the focus of geophysical work.In borehole observation system,the short distance between fractures and detectors leads to weak attenuation of elastic wave energy,and high-frequency source makes it easier to identify small-scale fractures.Compared to traditional monopole logging methods,dipole logging method has advantage of exciting pure shear waves sensitive to fractures,so its application is becoming increasingly widespread.However,since the reflected shear waves and scattered shear waves of fractures correspond to different fracture properties,how to distinguish and analyze these two kinds of waves is crucial for accurately characterizing the fracture parameters.To address this issue,numerical simulation of wave responses by a single fracture near a borehole in rock formation is performed,and the generation mechanism and characteristics of shear waves scattered by fractures are investigated.It is found that when the dip angle of the fracture surpasses a critical threshold,the S-wave will propagate to both endpoints of the fracture and generate scattered S-waves,resulting in two distinct scattered wave packets on the received waveform.When the polarization direction of the acoustic source is parallel to the strike of the fracture,the scattered SH-waves always have larger amplitude than the scattered SV-waves regardless of changing the fracture dip angle.Unlike SV-waves,the SH-waves scattered by the fracture do not have any mode conversion.Additionally,propagation of S-waves to a short length fracture can induce dipole mode vibration of the fracture within a wide frequency range.The phenomena of shear waves reflected and scattered by the fracture are further illustrated and verified by two field examples,thus showing the potential of scattered waves for fracture evaluation and characterization with borehole observation system.
文摘Spectral imaging for Earth observation^([1])is an advanced interdisciplinary research field at the forefront of remote sensing,geoscience,and information technology.It continues to develop and make breakthroughs in theoretical development,technological innovation,and industrial applications.In the era of rapid development in artificial intelligence and spectral imaging technology,the acquisition and processing of remote sensing information have become more intelligent.
基金The National Key Research and Development Program of China under contract Nos 2022YFC3104203 and 2018YFC0213103the Science Foundation of Donghai Laboratory under contract No.DH-2022KF01019+1 种基金the National Natural Science Foundation under contract No.419061522023 Shanghai Education Science Research Project under contract No.C2023120.
文摘Air-sea water vapor and CO_(2) flux observation experiments were carried out at the Yantai National Satellite Ocean Calibration Platform and the jetty at Monolithic Beach,Juehua Island,using a 100 Hz gas analyzer.The observations were corrected by employing wild point rejection,linear detrending,delay correction,coordinate rotation,time matching,and Webb,Pearman,and Leuning(WPL)correction.The results of spectral analysis and a turbulence development adequacy data quality check showed that the overall observation data quality was good.The air-sea water vapor and CO_(2) flux results showed that the observation duration affected both the air-sea flux intensity and direction at different observation frequencies.At shorter observation durations,the air-sea flux values measured at 100 Hz were smaller than the 20 Hz measurements and had opposite directions.In addition,the WPL correction reduced the overall air-sea flux and partially minimized the effect of observation frequency on the air-sea flux intensity.These results showed that high-frequency observations showed more turbulence variations than low-frequency observations.This conclusion could promote an understanding of small-scale turbulence variations.
