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新工科背景下基于OBE-CDIO理念的“食品工艺学”课程改革实践
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作者 夏继蓉 朱郑惠 +1 位作者 王春艳 陈永 《食品工业》 2026年第1期261-264,共4页
在新工科建设背景下,为应对食品产业对创新型工程技术人才的需求,针对传统“食品工艺学”课程存在的教学内容滞后性、教学设计不合理、考核方式单一等问题,开展了基于OBE-CDIO理念的课程改革实践。该改革旨在打造高质量的“食品工艺学... 在新工科建设背景下,为应对食品产业对创新型工程技术人才的需求,针对传统“食品工艺学”课程存在的教学内容滞后性、教学设计不合理、考核方式单一等问题,开展了基于OBE-CDIO理念的课程改革实践。该改革旨在打造高质量的“食品工艺学”课堂,提高教学质量,培养出更多的符合既定人才培养方案要求的新型食品专业人才。研究结果表明,经过该次课程改革实践,学生在食品工艺知识掌握、实践创新能力及综合素养方面均有显著提升。 展开更多
关键词 食品工艺学 obe-cdio 课程改革 新工科
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产教融合视域下应用型本科数字媒体技术专业VR实训课程改革研究——基于OBE-CDIO双理念的闭环设计与实践验证
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作者 邹子博 《教育教学研究前沿》 2026年第2期11-13,共3页
针对应用型本科数字媒体技术专业VR实训教学中存在的课程内容滞后(约18-24个月技术代差)、工程实践脱节及评价体系单一等结构性矛盾,本研究基于成果导向教育(Outcome-Based Education,OBE)与构思-设计-实现-运作(Conceive-Design-Implem... 针对应用型本科数字媒体技术专业VR实训教学中存在的课程内容滞后(约18-24个月技术代差)、工程实践脱节及评价体系单一等结构性矛盾,本研究基于成果导向教育(Outcome-Based Education,OBE)与构思-设计-实现-运作(Conceive-Design-Implement-Operate,CDIO)双理念,构建了“产业需求锚定—课程反向设计—虚实双轨实施—多元增值评价”的闭环改革模式。研究通过岗位能力映射重构“技术-艺术-管理”三维能力拓扑,利用云渲染与光学动捕技术搭建混合实训生态,并实施企业权重的全流程评价。实践表明,该模式有效提升了学生的Unity/Unreal引擎开发能力与复杂工程问题解决能力,毕业生岗位适配度达86%,为同类院校提供了可复制的教学范式。 展开更多
关键词 产教融合 数字媒体技术 VR实训 obe-cdio 虚实双轨 工程教育
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基于OBE-CDIO理念的机械精度设计课程体系改革与探索
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作者 付裕 万振帅 王赞 《河南教育(高教版)(中)》 2026年第1期69-70,共2页
针对机械精度设计课程的理论教学与实践应用脱节、工程能力培养结构性缺失等突出问题,以OBE(Outcome-Based Education)理念为引领,以CDIO(Conceive-Design-Implement-Operate)模式为路径,开展课程体系的创新重构。实施项目化教学,形成... 针对机械精度设计课程的理论教学与实践应用脱节、工程能力培养结构性缺失等突出问题,以OBE(Outcome-Based Education)理念为引领,以CDIO(Conceive-Design-Implement-Operate)模式为路径,开展课程体系的创新重构。实施项目化教学,形成公差设计与质量控制的闭环培养机制。教学实践证明,改革后学生的工程图样标准化程度与精度设计合理性显著提升,有效破解了传统课程中知识传授与工程实践“两张皮”的困境,为智能制造背景下机械类人才工程素养培养提供了系统化的课程改革方案。 展开更多
关键词 obe-cdio理念 机械精度设计 课程体系改革 创新能力
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Agri-Eval:Multi-level Large Language Model Valuation Benchmark for Agriculture
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作者 WANG Yaojun GE Mingliang +2 位作者 XU Guowei ZHANG Qiyu BIE Yuhui 《农业机械学报》 北大核心 2026年第1期290-299,共10页
Model evaluation using benchmark datasets is an important method to measure the capability of large language models(LLMs)in specific domains,and it is mainly used to assess the knowledge and reasoning abilities of LLM... Model evaluation using benchmark datasets is an important method to measure the capability of large language models(LLMs)in specific domains,and it is mainly used to assess the knowledge and reasoning abilities of LLMs.Therefore,in order to better assess the capability of LLMs in the agricultural domain,Agri-Eval was proposed as a benchmark for assessing the knowledge and reasoning ability of LLMs in agriculture.The assessment dataset used in Agri-Eval covered seven major disciplines in the agricultural domain:crop science,horticulture,plant protection,animal husbandry,forest science,aquaculture science,and grass science,and contained a total of 2283 questions.Among domestic general-purpose LLMs,DeepSeek R1 performed best with an accuracy rate of 75.49%.In the realm of international general-purpose LLMs,Gemini 2.0 pro exp 0205 standed out as the top performer,achieving an accuracy rate of 74.28%.As an LLMs in agriculture vertical,Shennong V2.0 outperformed all the LLMs in China,and the answer accuracy rate of agricultural knowledge exceeded that of all the existing general-purpose LLMs.The launch of Agri-Eval helped the LLM developers to comprehensively evaluate the model's capability in the field of agriculture through a variety of tasks and tests to promote the development of the LLMs in the field of agriculture. 展开更多
关键词 large language models assessment systems agricultural knowledge agricultural datasets
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Ecological Dynamics of a Logistic Population Model with Impulsive Age-selective Harvesting
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作者 DAI Xiangjun JIAO Jianjun 《应用数学》 北大核心 2026年第1期72-79,共8页
In this paper,we establish and study a single-species logistic model with impulsive age-selective harvesting.First,we prove the ultimate boundedness of the solutions of the system.Then,we obtain conditions for the asy... In this paper,we establish and study a single-species logistic model with impulsive age-selective harvesting.First,we prove the ultimate boundedness of the solutions of the system.Then,we obtain conditions for the asymptotic stability of the trivial solution and the positive periodic solution.Finally,numerical simulations are presented to validate our results.Our results show that age-selective harvesting is more conducive to sustainable population survival than non-age-selective harvesting. 展开更多
关键词 The logistic population model Selective harvesting Asymptotic stability EXTINCTION
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Modeling of Precipitation over Africa:Progress,Challenges,and Prospects
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作者 A.A.AKINSANOLA C.N.WENHAJI +21 位作者 R.BARIMALALA P.-A.MONERIE R.D.DIXON A.T.TAMOFFO M.O.ADENIYI V.ONGOMA I.DIALLO M.GUDOSHAVA C.M.WAINWRIGHT R.JAMES K.C.SILVERIO A.FAYE S.S.NANGOMBE M.W.POKAM D.A.VONDOU N.C.G.HART I.PINTO M.KILAVI S.HAGOS E.N.RAJAGOPAL R.K.KOLLI S.JOSEPH 《Advances in Atmospheric Sciences》 2026年第1期59-86,共28页
In recent years,there has been an increasing need for climate information across diverse sectors of society.This demand has arisen from the necessity to adapt to and mitigate the impacts of climate variability and cha... In recent years,there has been an increasing need for climate information across diverse sectors of society.This demand has arisen from the necessity to adapt to and mitigate the impacts of climate variability and change.Likewise,this period has seen a significant increase in our understanding of the physical processes and mechanisms that drive precipitation and its variability across different regions of Africa.By leveraging a large volume of climate model outputs,numerous studies have investigated the model representation of African precipitation as well as underlying physical processes.These studies have assessed whether the physical processes are well depicted and whether the models are fit for informing mitigation and adaptation strategies.This paper provides a review of the progress in precipitation simulation overAfrica in state-of-the-science climate models and discusses the major issues and challenges that remain. 展开更多
关键词 RAINFALL MONSOON climate modeling CORDEX CMIP6 convection-permitting models
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Stability of k-ε model in Kolmogorov flow
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作者 Jiashuo GUO Le FANG 《Applied Mathematics and Mechanics(English Edition)》 2026年第1期165-184,共20页
The Reynolds-averaged Navier-Stokes(RANS)technique enables critical engineering predictions and is widely adopted.However,since this iterative computation relies on the fixed-point iteration,it may converge to unexpec... The Reynolds-averaged Navier-Stokes(RANS)technique enables critical engineering predictions and is widely adopted.However,since this iterative computation relies on the fixed-point iteration,it may converge to unexpected non-physical phase points in practice.We conduct an analysis on the phase-space characteristics and the fixed-point theory underlying the k-ε turbulence model,and employ the classical Kolmogorov flow as a framework,leveraging its direct numerical simulation(DNS)data to construct a one-dimensional(1D)system under periodic/fixed boundary conditions.The RANS results demonstrate that under periodic boundary conditions,the k-ε model exhibits only a unique trivial fixed point,with asymptotes capturing the phase portraits.The stability of this trivial fixed point is determined by a mathematically derived stability phase diagram,indicating the fact that the k-ε model will never converge to correct values under periodic conditions.In contrast,under fixed boundary conditions,the model can yield a stable non-trivial fixed point.The evolutionary mechanisms and their relationship with boundary condition settings systematically explain the inherent limitations of the k-ε model,i.e.,its deficiency in computing the flow field under periodic boundary conditions and sensitivity to boundary-value specifications under fixed boundary conditions.These conclusions are finally validated with the open-source code OpenFOAM. 展开更多
关键词 k-εmodel Kolmogorov flow INSTABILITY turbulence model
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Design optimization and FEA of B-6 and B-7 levels ballistics armor:A modelling approach
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作者 Muhammad Naveed CHU Jinkui +1 位作者 Atif Ur Rehman Arsalan Hyder 《大连理工大学学报》 北大核心 2026年第1期66-77,共12页
Utilizing finite element analysis,the ballistic protection provided by a combination of perforated D-shaped and base armor plates,collectively referred to as radiator armor,is evaluated.ANSYS Explicit Dynamics is empl... Utilizing finite element analysis,the ballistic protection provided by a combination of perforated D-shaped and base armor plates,collectively referred to as radiator armor,is evaluated.ANSYS Explicit Dynamics is employed to simulate the ballistic impact of 7.62 mm armor-piercing projectiles on Aluminum AA5083-H116 and Steel Secure 500 armors,focusing on the evaluation of material deformation and penetration resistance at varying impact points.While the D-shaped armor plate is penetrated by the armor-piercing projectiles,the combination of the perforated D-shaped and base armor plates successfully halts penetration.A numerical model based on the finite element method is developed using software such as SolidWorks and ANSYS to analyze the interaction between radiator armor and bullet.The perforated design of radiator armor is to maintain airflow for radiator function,with hole sizes smaller than the bullet core diameter to protect radiator assemblies.Predictions are made regarding the brittle fracture resulting from the projectile core′s bending due to asymmetric impact,and the resulting fragments failed to penetrate the perforated base armor plate.Craters are formed on the surface of the perforated D-shaped armor plate due to the impact of projectile fragments.The numerical model accurately predicts hole growth and projectile penetration upon impact with the armor,demonstrating effective protection of the radiator assemblies by the radiator armor. 展开更多
关键词 radiator armor ballistics simulation Johnson-Cook model armor-piercing projectile perforated D-shaped armor plate
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CIT-Rec:Enhancing Sequential Recommendation System with Large Language Models
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作者 Ziyu Li Zhen Chen +2 位作者 Xuejing Fu Tong Mo Weiping Li 《Computers, Materials & Continua》 2026年第3期2328-2343,共16页
Recommendation systems are key to boosting user engagement,satisfaction,and retention,particularly on media platforms where personalized content is vital.Sequential recommendation systems learn from user-item interact... Recommendation systems are key to boosting user engagement,satisfaction,and retention,particularly on media platforms where personalized content is vital.Sequential recommendation systems learn from user-item interactions to predict future items of interest.However,many current methods rely on unique user and item IDs,limiting their ability to represent users and items effectively,especially in zero-shot learning scenarios where training data is scarce.With the rapid development of Large Language Models(LLMs),researchers are exploring their potential to enhance recommendation systems.However,there is a semantic gap between the linguistic semantics of LLMs and the collaborative semantics of recommendation systems,where items are typically indexed by IDs.Moreover,most research focuses on item representations,neglecting personalized user modeling.To address these issues,we propose a sequential recommendation framework using LLMs,called CIT-Rec,a model that integrates Collaborative semantics for user representation and Image and Text information for item representation to enhance Recommendations.Specifically,by aligning intuitive image information with text containing semantic features,we can more accurately represent items,improving item representation quality.We focus not only on item representations but also on user representations.To more precisely capture users’personalized preferences,we use traditional sequential recommendation models to train on users’historical interaction data,effectively capturing behavioral patterns.Finally,by combining LLMs and traditional sequential recommendation models,we allow the LLM to understand linguistic semantics while capturing collaborative semantics.Extensive evaluations on real-world datasets show that our model outperforms baseline methods,effectively combining user interaction history with item visual and textual modalities to provide personalized recommendations. 展开更多
关键词 Large language models vision language models sequential recommendation instruction tuning
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OBE-CDIO导向下中药学专业的药物分析实验教学改革实践
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作者 尹丽 卢成淑 崔婷 《科技风》 2026年第6期57-59,共3页
针对中药学专业药物分析实验教学存在的验证性实验占比高、创新不足、大型仪器利用率低等问题,融合OBE与CDIO理念,以火焰原子吸收光谱法测定罗汉果钾元素为案例展开改革。通过实验方案设计、流程优化、规范操作及项目运行四个环节,系统... 针对中药学专业药物分析实验教学存在的验证性实验占比高、创新不足、大型仪器利用率低等问题,融合OBE与CDIO理念,以火焰原子吸收光谱法测定罗汉果钾元素为案例展开改革。通过实验方案设计、流程优化、规范操作及项目运行四个环节,系统革新教学体系:第一,引入虚拟仿真预习,强化仪器操作规范;第二,采用问题驱动设计,优化消解体系与参数;第三,构建过程性评价指标,覆盖知识掌握、数据分析、团队协作等维度。实践表明,改革后学生仪器操作合格率提升42%,自主设计实验比例达65%,实现“理论-实践-应用”能力的深度融合,为中药分析人才培养提供了可推广的教学模式。 展开更多
关键词 obe-cdio理念 中药学专业 药物分析实验教学 火焰原子吸收分光光度法 过程性评价
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Lithospheric magnetic variations on the Tibetan Plateau based on a 3D surface spline model,compared with strong earthquake occurrences
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作者 PengTao Zhang Jun Yang +3 位作者 LiLi Feng Xia Li YuHong Zhao YingFeng Ji 《Earth and Planetary Physics》 2026年第1期30-43,共14页
The National Geophysical Data Center(NGDC)of the United States has collected aeromagnetic data for input into a series of geomagnetic models to improve model resolution;however,in the Tibetan Plateau region,ground-bas... The National Geophysical Data Center(NGDC)of the United States has collected aeromagnetic data for input into a series of geomagnetic models to improve model resolution;however,in the Tibetan Plateau region,ground-based observations remain insufficient to clearly reflect the characteristics of the region’s lithospheric magnetism.In this study,we evaluate the lithospheric magnetism of the Tibetan Plateau by using a 3D surface spline model based on observations from>200 newly constructed repeat stations(portable stations)to determine the spatial distribution of plateau geomagnetism,as well as its correlation with the tectonic features of the region.We analyze the relationships between M≥5 earthquakes and lithospheric magnetic field variations on the Tibetan Plateau and identify regions susceptible to strong earthquakes.We compare the geomagnetic results with those from an enhanced magnetic model(EMM2015)developed by the NGDC and provide insights into improving lithospheric magnetic field calculations in the Tibetan Plateau region.Further research reveals that these magnetic anomalies exhibit distinct differences from the magnetic-seismic correlation mechanisms observed in other tectonic settings;here,they are governed primarily by the combined effects of compressional magnetism,thermal magnetism,and deep thermal stress.This study provides new evidence of geomagnetic anomalies on the Tibetan Plateau,interprets them physically,and demonstrates their potential for identifying seismic hazard zones on the Plateau. 展开更多
关键词 Tibetan Plateau magnetic variation SEISMICITY surface spline model enhanced magnetic model
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UAV-to-Ground Channel Modeling:(Quasi-)Closed-Form Channel Statistics and Manual Parameter Estimation
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作者 Zeng Linzhou Liao Xuewen +3 位作者 Xie Wenwu Ma Zhangfeng Xiong Baiping Jiang Hao 《China Communications》 2026年第1期47-66,共20页
(Quasi-)closed-form results for the statistical properties of unmanned aerial vehicle(UAV)airto-ground channels are derived for the first time using a novel spatial-vector-based method from a threedimensional(3-D)arbi... (Quasi-)closed-form results for the statistical properties of unmanned aerial vehicle(UAV)airto-ground channels are derived for the first time using a novel spatial-vector-based method from a threedimensional(3-D)arbitrary-elevation one-cylinder model.The derived results include a closed-form expression for the space-time correlation function and some quasi-closed-form ones for the space-Doppler power spectrum density,the level crossing rate,and the average fading duration,which are shown to be the generalizations of those previously obtained from the two-dimensional(2-D)one-ring model and the 3-D low-elevation one-cylinder model for terrestrial mobile-to-mobile channels.The close agreements between the theoretical results and the simulations as well as the measurements validate the utility of the derived channel statistics.Based on the derived expressions,the impacts of some parameters on the channel characteristics are investigated in an effective,efficient,and explicable way,which leads to a general guideline on the manual parameter estimation from the measurement description. 展开更多
关键词 channel characteristics geometry-based stochastic model manual parameter estimation UAV channel modeling
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Ecological restoration model selection for abandoned mines in the Luo River Basin,Eastern Qinling Mountains
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作者 HUANG Yuming GAO Ningze +1 位作者 ZHANG Hanyuan ZHENG Wenlong 《Journal of Mountain Science》 2026年第1期358-369,共12页
Effective management of mining areas in the Luo River Basin,located in the eastern Qinling Mountains,is vital for the integrated protection and restoration needed to support the high-quality development of the Yellow ... Effective management of mining areas in the Luo River Basin,located in the eastern Qinling Mountains,is vital for the integrated protection and restoration needed to support the high-quality development of the Yellow River Basin.Using the‘cupball'model,this study analyzes the limiting factors and restoration characteristics across four mining areas and proposes a conceptual model for selecting appropriate restoration approaches.A second conceptual model is then introduced to address regional development needs,incorporating ecological conservation,safety protection,and people's wellbeing.The applicability of the integrated model selection framework is demonstrated through a case study on the south bank of the Qinglongjian River.The results indicate that:(1)The key limiting factors are similar across cases,but the degree of ecological degradation varies.(2)Mildly degraded areas are represented by a shallower and narrower‘cup',where natural recovery is the preferred approach,whereas moderately and severely degraded systems call for assisted regeneration and ecological reconstruction,respectively.(3)When the restoration models determined based on limiting factors and development needs are consistent,the model is directly applicable;if they differ,the option involving less artificial intervention is preferred;(4)Monitoring of the restored mining area on the Qinglongjian River's south bank confirms significant improvements in soil erosion control and vegetation coverage.This study provides a transferable methodology for balancing resource extraction with ecosystem conservation,offering practical insights for other ecologically vulnerable mining regions. 展开更多
关键词 Luo River Basin Cup-ball model Mine restoration Ecological degradation Conceptual model Development needs
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Do Higher Horizontal Resolution Models Perform Better?
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作者 Shoji KUSUNOKI 《Advances in Atmospheric Sciences》 2026年第1期259-262,共4页
Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(... Climate model prediction has been improved by enhancing model resolution as well as the implementation of sophisticated physical parameterization and refinement of data assimilation systems[section 6.1 in Wang et al.(2025)].In relation to seasonal forecasting and climate projection in the East Asian summer monsoon season,proper simulation of the seasonal migration of rain bands by models is a challenging and limiting factor[section 7.1 in Wang et al.(2025)]. 展开更多
关键词 enhancing model resolution refinement data assimilation systems section climate model climate projection higher horizontal resolution seasonal forecasting simulation seasonal migration rain bands model resolution
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A peridynamics modeling approach for pre-cracked rock cracking processes under impact by integrating Drucker-Prager plasticity model and efficient contact model
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作者 Jingzhi Tu Nengxiong Xu Gang Mei 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第1期179-195,共17页
In rock engineering,natural cracks in rock masses subjected to external loads tend to initiate and propagate,leading to potential safety hazards.To investigate the effect of cracking behavior on the mechanical propert... In rock engineering,natural cracks in rock masses subjected to external loads tend to initiate and propagate,leading to potential safety hazards.To investigate the effect of cracking behavior on the mechanical properties of rocks,the cracking processes of pre-cracked rocks have been extensively studied using numerical modeling methods.The peridynamics(PD)exhibits advantages over other numerical methods due to the absence of the requirements for remeshing and external crack growth criterion.However,for modeling pre-cracked rock cracking processes under impact,current PD implementations lack generally applicable rock constitutive models and impact contact models,which leads to difficulties in determining rock material parameters and efficiently calculating impact loads.This paper proposes a non-ordinary state-based peridynamics(NOSBPD)modeling method integrating the Drucker-Prager(DP)plasticity model and an efficient contact model to address the above problems.In the proposed method,the Drucker-Prager plasticity model is integrated into the NOSBPD,thereby equipping NOSBPD with the capability to accurately characterize the nonlinear stress-strain relationship inherent in rocks.An efficient contact model between particles and meshes is designed to calculate the impact loads,which is essentially a coupling method of PD with the finite element method(FEM).The effectiveness of the proposed NOSBPD modeling method is verified by comparison with other numerical methods and experiments.Experimental results indicate that the proposed method can effectively and accurately predict the 3D cracking processes of pre-cracked cracks under impact loading,and the maximum principal stress is the key driver behind wing crack formation in pre-cracked rocks. 展开更多
关键词 Pre-cracked rocks Cracking processes Non-ordinary state-based peridynamics (NOSBPD) Drucker-Prager plasticity model Efficient contact model
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Secured-FL:Blockchain-Based Defense against Adversarial Attacks on Federated Learning Models
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作者 Bello Musa Yakubu Nor Shahida Mohd Jamail +1 位作者 Rabia Latif Seemab Latif 《Computers, Materials & Continua》 2026年第3期734-757,共24页
Federated Learning(FL)enables joint training over distributed devices without data exchange but is highly vulnerable to attacks by adversaries in the form of model poisoning and malicious update injection.This work pr... Federated Learning(FL)enables joint training over distributed devices without data exchange but is highly vulnerable to attacks by adversaries in the form of model poisoning and malicious update injection.This work proposes Secured-FL,a blockchain-based defensive framework that combines smart contract-based authentication,clustering-driven outlier elimination,and dynamic threshold adjustment to defend against adversarial attacks.The framework was implemented on a private Ethereum network with a Proof-of-Authority consensus algorithm to ensure tamper-resistant and auditable model updates.Large-scale simulation on the Cyber Data dataset,under up to 50%malicious client settings,demonstrates Secured-FL achieves 6%-12%higher accuracy,9%-15%lower latency,and approximately 14%less computational expense compared to the PPSS benchmark framework.Additional tests,including confusion matrices,ROC and Precision-Recall curves,and ablation tests,confirm the interpretability and robustness of the defense.Tests for scalability also show consistent performance up to 500 clients,affirming appropriateness to reasonably large deployments.These results make Secured-FL a feasible,adversarially resilient FL paradigm with promising potential for application in smart cities,medicine,and other mission-critical IoT deployments. 展开更多
关键词 Federated learning(FL) blockchain FL based privacy model defense FL model security ethereum smart contract
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Three-Dimensional Hybrid Model for Wave Interaction with Porous Layer
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作者 Divya Ramesh Sriram Venkatachalam 《Computer Modeling in Engineering & Sciences》 2026年第1期577-603,共27页
A hybrid model combining Fully Non-Linear Potential Flow Theory(FNPT)based on the Finite Element Method(FEM)and the Unified Navier-Stokes equation,using the 3D Improved Meshless Local Petrov Galerkin method with Ranki... A hybrid model combining Fully Non-Linear Potential Flow Theory(FNPT)based on the Finite Element Method(FEM)and the Unified Navier-Stokes equation,using the 3D Improved Meshless Local Petrov Galerkin method with Rankine Source(IMLPG_R),is developed to study wave interactions with a porous layer.In previous studies,the above formulations are applied to wave interaction with fixed cylindrical structures.The present study extends this framework by integrating a unified governing equation within the hybrid modeling approach to capture the dynamics of wave interaction with porous media.The porous layers are employed to replicate the wave-dissipating behavior of the structure.A weak coupling strategy is implemented within a designated buffer zone,wherein field variables from the 2D Fully Nonlinear Potential Theory(FNPT)simulations are transferred to the 3D Improved Moving Least Squares-based Petrov-Galerkin(IMLPG_R)model at each time step.This domain decomposition significantly reduces computational cost compared to a full 3D simulation by partitioning the domain into two subregions:the FNPT domain representing the far-field without structures,and the IMLPG_R domain encompassing the porous region.The Unified Navier-Stokes formulation is extended by incorporating additional drag forces governed by Darcy’s law to model the resistance introduced by the porous medium.A stationary background node framework is utilized for interpolation by fluid particles at each time step to accommodate the porous representation.To enhance numerical stability and accuracy,particularly in the presence of sloping boundaries,the Particle Shifting Technique(PST)is integrated into the IMLPG_R model.This implementation involves a modified version of the PST algorithm,where key parameters such as the weight function,velocity ratio,and radius of influence are optimized for IMLPG_R.This is the first time the application of 3D IMLPG_R for porous structure has been reported.Further,the model is subsequently validated against experimental data. 展开更多
关键词 FNPT IMLPG_R hybrid model PST
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Review of machine learning tight-binding models:Route to accurate and scalable electronic simulations
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作者 Jijie Zou Zhanghao Zhouyin +1 位作者 Shishir Kumar Pandey Qiangqiang Gu 《Chinese Physics B》 2026年第1期2-12,共11页
The rapid advancement of machine learning based tight-binding Hamiltonian(MLTB)methods has opened new avenues for efficient and accurate electronic structure simulations,particularly in large-scale systems and long-ti... The rapid advancement of machine learning based tight-binding Hamiltonian(MLTB)methods has opened new avenues for efficient and accurate electronic structure simulations,particularly in large-scale systems and long-time scenarios.This review begins with a concise overview of traditional tight-binding(TB)models,including both(semi-)empirical and first-principles approaches,establishing the foundation for understanding MLTB developments.We then present a systematic classification of existing MLTB methodologies,grouped into two major categories:direct prediction of TB Hamiltonian elements and inference of empirical parameters.A comparative analysis with other ML-based electronic structure models is also provided,highlighting the advancement of MLTB approaches.Finally,we explore the emerging MLTB application ecosystem,highlighting how the integration of MLTB models with a diverse suite of post-processing tools from linear-scaling solvers to quantum transport frameworks and molecular dynamics interfaces is essential for tackling complex scientific problems across different domains.The continued advancement of this integrated paradigm promises to accelerate materials discovery and open new frontiers in the predictive simulation of complex quantum phenomena. 展开更多
关键词 machine learning tight-binding model electronic simulations
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Establishment of a biosafe murine model of skeletal tuberculosis using Mycobacterium smegmatis
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作者 Yewei Jia Yuhuai Guo +10 位作者 Yusheng Yang Jie Zhang Ziyang Zhang Ying Qu Jiulin Tan Jie Shen Nathachit Limjunyawong Jianzhong Xu Zehua Zhang Fei Luo Ce Dou 《Animal Models and Experimental Medicine》 2026年第1期5-20,共16页
Background:Skeletal tuberculosis(TB)remains a persistent clinical and research chal-lenge due to its chronic course,osteolytic destruction,and the limitations of existing animal models,which often require high-level b... Background:Skeletal tuberculosis(TB)remains a persistent clinical and research chal-lenge due to its chronic course,osteolytic destruction,and the limitations of existing animal models,which often require high-level biosafety containment or fail to repli-cate human skeletal pathology.Methods:This study developed a biosafe,accessible,and versatile murine model of skeletal TB using Mycobacterium smegmatis,a fast-growing,nonpathogenic myco-bacterial species with high genomic homology to Mycobacterium tuberculosis.Three infection routes-subperiosteal calvarial injection,intratibial injection,and intra-cardiac inoculation-were systematically evaluated for their ability to induce lo-calized versus disseminated bone infection under standard biosafety level(BSL)-1 conditions.Results:Subperiosteal calvarial and intratibial injection of M.smegmatis induced local-ized bone lesions characterized by osteolysis,sequestrum formation,granulomatous inflammation,and increased osteoclast activity.Intratibial infection additionally trig-gered compartment-specific immune responses,including neutrophil and macrophage expansion,transient B-cell depletion,and activation of interferon-γ^(+)(IFN-γ^(+))T cells,reflecting active immune remodeling at the infection site.Systemic dissemination via intracardiac injection reproducibly generated progressive vertebral and tibial bone destruction with organized granuloma formation and immune cell infiltration but without prominent sequestrum formation.Compared to intratibial infection,intracar-diac delivery exhibited lower intragroup variability and more closely recapitulated the diffuse progression of extrapulmonary skeletal tuberculosis.Conclusions:This M.smegmatis-based murine model provides a straightforward,reliable,and immunopathologically relevant platform for exploring host-pathogen dynamics,immune-driven bone destruction,and early-stage therapeutic testing in skeletal TB,all within standard BSL-1 laboratories.This model fills a critical gap by enabling BSL-1 research into skeletal TB mechanisms and drug development. 展开更多
关键词 bone tuberculosis murine model Mycobacterium smegmatis TUBERCULOSIS
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A Predictive Model for the Elastic Modulus of High-Strength Concrete Based on Coarse Aggregate Characteristics
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作者 LI Liangshun LI Huajian +2 位作者 HUANG Fali YANG Zhiqiang DONG Haoliang 《Journal of Wuhan University of Technology(Materials Science)》 2026年第1期121-137,共17页
To investigate the influence of coarse aggregate parent rock properties on the elastic modulus of concrete,the mineralogical properties and stress-strain curves of granite and dolomite parent rocks,as well as the stre... To investigate the influence of coarse aggregate parent rock properties on the elastic modulus of concrete,the mineralogical properties and stress-strain curves of granite and dolomite parent rocks,as well as the strength and elastic modulus of mortar and concrete prepared with mechanism aggregates of the corresponding lithology,and the stress-strain curves of concrete were investigated.In this paper,a coarse aggregate and mortar matrix bonding assumption is proposed,and a prediction model for the elastic modulus of mortar is established by considering the lithology of the mechanism sand and the slurry components.An equivalent coarse aggregate elastic modulus model was established by considering factors such as coarse aggregate particle size,volume fraction,and mortar thickness between coarse aggregates.Based on the elastic modulus of the equivalent coarse aggregate and the remaining mortar,a prediction model for the elastic modulus of the two and three components of concrete in series and then in parallel was established,and the predicted values differed from the measured values within 10%.It is proposed that the coarse aggregate elastic modulus in highstrength concrete is the most critical factor affecting the elastic modulus of concrete,and as the coarse aggregate elastic modulus increases by 27.7%,the concrete elastic modulus increases by 19.5%. 展开更多
关键词 elastic modulus prediction model MINERALOGICAL influence mechanism
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