A facile and selective route for O-alkylation of highly hydrophilic, multifunctional hyperbranched polyglycerol (PG) under non-aqueous phase transfer catalyzed conditions in dimethyl sulfoxide was developed, through w...A facile and selective route for O-alkylation of highly hydrophilic, multifunctional hyperbranched polyglycerol (PG) under non-aqueous phase transfer catalyzed conditions in dimethyl sulfoxide was developed, through which several kinds of groups were introduced onto PG.展开更多
O-Alkylation of oximes with N-vinylpyrrolidin-2-one or N-methyl-N-vinylacetamide was efficiently initiated by a catalytic amount of cerium（Ⅳ） ammonium nitrate（CAN）,giving the corresponding oxime ether derivatives...O-Alkylation of oximes with N-vinylpyrrolidin-2-one or N-methyl-N-vinylacetamide was efficiently initiated by a catalytic amount of cerium（Ⅳ） ammonium nitrate（CAN）,giving the corresponding oxime ether derivatives in good yield.展开更多
A convenient synthetic approach leading to protected inositol was described based on regioselective O-alkylation using alkyl halide under solid-liquid PTC condition
A series of rotenone O-alkyl oxime derivatives was designed and synthesized. Their structures were confirmed by elemental analyses, Fourier transform infrared（FTIR） and 1H NMR spectral studies, and the typical cryst...A series of rotenone O-alkyl oxime derivatives was designed and synthesized. Their structures were confirmed by elemental analyses, Fourier transform infrared（FTIR） and 1H NMR spectral studies, and the typical crystal structure of rotenone O-ethyl oxime（3b） was determined by X-ray diffraction. The preliminary biological activities of the new compounds were evaluated. The results of bioassays indicate that the title compounds exhibit moderate insecticidal and bactericidal activities. Among the synthesized compounds, compound 3q exhibited 90.0% mortality against M. separata at 1000 μg/mL. Compounds 3b and 3g exhibited both 90.0% inhibition rate against R. solani at 500 μg/mL, respectively.展开更多
A series of new diethers were obtained by alkylation of furoin under microwave irradiation （MWI） in phase transfer catalysis （PTC） conditions. The products of alkyl halides were synthesized in good yields （〉75%...A series of new diethers were obtained by alkylation of furoin under microwave irradiation （MWI） in phase transfer catalysis （PTC） conditions. The products of alkyl halides were synthesized in good yields （〉75%） within a few minutes, and the products of dihalides were synthesized in fair yields （about 45%）. The yields are dramatically improved compared to conventional heating under the same conditions, in spite of similar profiles of rising in temperature.展开更多
Compounds having an active hydroxy group, such as, acyloins can be easily alkylated by alkyl halides in the presence of a phase transfer catalyst （PTC）. The reaction is usually carried out in the presence of con-cen...Compounds having an active hydroxy group, such as, acyloins can be easily alkylated by alkyl halides in the presence of a phase transfer catalyst （PTC）. The reaction is usually carried out in the presence of con-centrated aqueous sodium or potassium hydroxide and a phase transfer catalyst, such as, quaternary ammonium salts^[1-3] species, miscible which facilitate the interphase transfer of making reactions between reagents in two im-phases possible. The reaction involves a series of equilibrium and mass-transfer steps.展开更多
Visible light-induced transformation of CO_(2) and CS_(2) into value-added products has attracted worldwide attention because it mimics nature.In this context,although visible-light-induced direct synthesis of dithioc...Visible light-induced transformation of CO_(2) and CS_(2) into value-added products has attracted worldwide attention because it mimics nature.In this context,although visible-light-induced direct synthesis of dithiocarbamates and carbamates employing SO_(2) and CO_(2) as a C1 source has been reported,all these reactions are limited to the preparation of S-alkyl mono-dithiocarbamates and O-alkyl mono-carbamates.Herein,we report a visible-light photoredox-catalyzed multicomponent reaction of diazosulfonium triflates with amines and CS_(2) or CO_(2).Mechanistic studies indicate that the diazomethyl radicals might be generated as the key intermediates,thus providing a direction for the application of diazomethyl radicals with other radical acceptors.展开更多
THE chemistry of nitronic esters remains relatively unknown due to their conspicuous feature ofinstability. In the preceding papers, we described the late progress in the researchof nitronic esters: (i) nitronic ester...THE chemistry of nitronic esters remains relatively unknown due to their conspicuous feature ofinstability. In the preceding papers, we described the late progress in the researchof nitronic esters: (i) nitronic esters were first synthesized via O-alkylation of the alkali met-展开更多
文摘A facile and selective route for O-alkylation of highly hydrophilic, multifunctional hyperbranched polyglycerol (PG) under non-aqueous phase transfer catalyzed conditions in dimethyl sulfoxide was developed, through which several kinds of groups were introduced onto PG.
基金Project 20572040 was supported by National Natural Science Foundation of China
文摘O-Alkylation of oximes with N-vinylpyrrolidin-2-one or N-methyl-N-vinylacetamide was efficiently initiated by a catalytic amount of cerium（Ⅳ） ammonium nitrate（CAN）,giving the corresponding oxime ether derivatives in good yield.
文摘A convenient synthetic approach leading to protected inositol was described based on regioselective O-alkylation using alkyl halide under solid-liquid PTC condition
基金Supported by the National Science and Technology Pillar Program of China(No.2011BAE06B01)
文摘A series of rotenone O-alkyl oxime derivatives was designed and synthesized. Their structures were confirmed by elemental analyses, Fourier transform infrared（FTIR） and 1H NMR spectral studies, and the typical crystal structure of rotenone O-ethyl oxime（3b） was determined by X-ray diffraction. The preliminary biological activities of the new compounds were evaluated. The results of bioassays indicate that the title compounds exhibit moderate insecticidal and bactericidal activities. Among the synthesized compounds, compound 3q exhibited 90.0% mortality against M. separata at 1000 μg/mL. Compounds 3b and 3g exhibited both 90.0% inhibition rate against R. solani at 500 μg/mL, respectively.
基金Natural Science Foundation of Jilin Province, China （No. 1999010540）.
文摘A series of new diethers were obtained by alkylation of furoin under microwave irradiation （MWI） in phase transfer catalysis （PTC） conditions. The products of alkyl halides were synthesized in good yields （〉75%） within a few minutes, and the products of dihalides were synthesized in fair yields （about 45%）. The yields are dramatically improved compared to conventional heating under the same conditions, in spite of similar profiles of rising in temperature.
基金Supported by the Natural Science Foundation of Jilin Province,China(No.1999010540).
文摘Compounds having an active hydroxy group, such as, acyloins can be easily alkylated by alkyl halides in the presence of a phase transfer catalyst （PTC）. The reaction is usually carried out in the presence of con-centrated aqueous sodium or potassium hydroxide and a phase transfer catalyst, such as, quaternary ammonium salts^[1-3] species, miscible which facilitate the interphase transfer of making reactions between reagents in two im-phases possible. The reaction involves a series of equilibrium and mass-transfer steps.
基金Financial support of this research by the Natural Sciences Foundation of Jilin Province(20240101176JC)National Natural Sciences Foundation of China(21871044)is greatly acknowledged.
文摘Visible light-induced transformation of CO_(2) and CS_(2) into value-added products has attracted worldwide attention because it mimics nature.In this context,although visible-light-induced direct synthesis of dithiocarbamates and carbamates employing SO_(2) and CO_(2) as a C1 source has been reported,all these reactions are limited to the preparation of S-alkyl mono-dithiocarbamates and O-alkyl mono-carbamates.Herein,we report a visible-light photoredox-catalyzed multicomponent reaction of diazosulfonium triflates with amines and CS_(2) or CO_(2).Mechanistic studies indicate that the diazomethyl radicals might be generated as the key intermediates,thus providing a direction for the application of diazomethyl radicals with other radical acceptors.
文摘THE chemistry of nitronic esters remains relatively unknown due to their conspicuous feature ofinstability. In the preceding papers, we described the late progress in the researchof nitronic esters: (i) nitronic esters were first synthesized via O-alkylation of the alkali met-
