Heat transfer coefficients in nucleate pool boiling were measured on a horizontal copper surface for refrigerants, HFC-134a, HFC-32, and HFC-125, their binary and ternary mixtures under saturated conditions at 0.9MPa....Heat transfer coefficients in nucleate pool boiling were measured on a horizontal copper surface for refrigerants, HFC-134a, HFC-32, and HFC-125, their binary and ternary mixtures under saturated conditions at 0.9MPa. Compared to pure components, both binary and ternary mixtures showed lower heat transfer coefficients.This deterioration was more pronounced as heat flux was increased. Experimental data were compared with some empirical and semi-empirical correlations available in literature. For binary mixture, the accuracy of the correlations varied considerably with mixtures and the heat flux. Experimental data for HFC-32/134a/125 were also compared with available correlated equation obtained by Thome. For ternary mixture, the boiling range of binary mixture composed by the pure fluids with the lowest and the medium boiling points, and their concentration difference had important effects on boiling heat transfer coefficients.展开更多
A novel kind of multi-core magnetic composite particles, the surfaces of which were respectively mo- dified with goat-anti-mouse IgG and antitransferrin receptor（anti-CD71）, was prepared. The fetal nucleated red blo...A novel kind of multi-core magnetic composite particles, the surfaces of which were respectively mo- dified with goat-anti-mouse IgG and antitransferrin receptor（anti-CD71）, was prepared. The fetal nucleated red blood cells（FNRBCs） in the peripheral blood of a gravida were rapidly and effectively enriched and separated by the mo- dified multi-core magnetic composite particles in an external magnetic field. The obtained FNRBCs were used for the identification of the fetal sex by means of fluorescence in situ hybridization（FISH） technique. The results demonstrate that the multi-core magnetic composite particles meet the requirements for the enrichment and speration of FNRBCs with a low concentration and the accuracy of detetion for the diagnosis of fetal sex reached to 95%. Moreover, the obtained FNRBCs were applied to the non-invasive diagnosis of Down syndrome and chromosome 3p21 was de- tected. The above facts indicate that the novel multi-core magnetic composite particles-based method is simple, relia- ble and cost-effective and has opened up vast vistas for the potential application in clinic non-invasive prenatal diag- nosis.展开更多
This paper presents results of an experimental investigation carried out to determine the effects of surface material on nucleate pool boiling heat transfer of refrigerant R113. Experiments were performed on horizonta...This paper presents results of an experimental investigation carried out to determine the effects of surface material on nucleate pool boiling heat transfer of refrigerant R113. Experiments were performed on horizontal circular plates of brass, copper and aluminum. The heat transfer coefficient was evaluated by measuring wall superheat and effective heat flux removed by boiling. The experiments were carried out in the heat flux range of 8 to 200 kW/m2. The obtained results have shown significant effect of surface material, with copper providing the highest heat transfer coefficient among the samples, and aluminum the least. There was negligible difference at low heat fluxes, but copper showed 23% better performance at high heat fluxes than aluminum and 18% better than brass.展开更多
To find a simple, effective method of isolating fetal cells from maternal peripheral blood for prenatal diagnosis, 45 women were studied with their gestation being 6-14 weeks and age 21- 30 years. The fetal cells wer...To find a simple, effective method of isolating fetal cells from maternal peripheral blood for prenatal diagnosis, 45 women were studied with their gestation being 6-14 weeks and age 21- 30 years. The fetal cells were isolated from maternal blood by using discontinuous density gradient centrifugation. Some of the isolated cells were made smear and counted under the microscope; others were used for predicting fetal sex by PCR amplification of Y chromosome specific DYZ1 gene. The major cells in the upper separation interface were lymphocytes and monocytes, with occasionally seen nucleated red blood cells (NRBC); while those in the middle separation interface were neutrocytes, with NRBC scattering. The ratio of NRBC/nucleated cells was 1. 98±0. 28× 10-5. There was no significant difference between the first and second trimester (P>0. 05). The amount of isolated fetal cells was sufficient for prenatal genetic diagnosis. Male pregnancy was correctly predicted in 10 out of 13 cases. It is concluded that the method of discontinuous density gradient centrifugation was of considerable importance in the development of non-invasive prenatal genetic diagnosis.展开更多
Based on the tests of more than ten different additives, several effective additives are found capable of improving the boiling heat transfer behavior of water pronouncedly. The mechanism of the enhancement of nucleat...Based on the tests of more than ten different additives, several effective additives are found capable of improving the boiling heat transfer behavior of water pronouncedly. The mechanism of the enhancement of nucleate boiling with additives has been investigated, and the results indicate that one of the important reasons is that the nucleation sites have been increased.展开更多
The effect of clay on the nucleating behavior of 1,3：2,4-bis（3,4-dimethylbenzylidene） sorbitol （DMDBS） in cryatallization of isotactic polypropylene （iPP） was investigated by means of differential scanning calo...The effect of clay on the nucleating behavior of 1,3：2,4-bis（3,4-dimethylbenzylidene） sorbitol （DMDBS） in cryatallization of isotactic polypropylene （iPP） was investigated by means of differential scanning calorimetry （DSC）, dynamic rheology and polarized light microscopy （PLM）. It is interesting to note that the incorporation of layered clay nanoparticles into DMDBS-nucleated iPP may induce a synergetic nucleation effect while the DMDBS content is below 0.1 wt%, otherwise it restricts the crystallization rate prominently as the DMDBS content increases up to 0.3 wt%, which has exceeded the content threshold to yield a nucleating agent （NA） network. As shown by dynamic rheological investigations, the clay nanoparticles demonstrate an obstructive effect of disturbing the consistency of DMDBS fibrils network. Moreover, to further demonstrate the importance of NA network formation in the crystallization of iPP, we used another NA named HPN-20e, which can not form network structure at all over the concentration studied, for comparison. In this case, the nucleated-crystallization rate is independent on the addition of clay nanoparticles, as the nucleating mechanism is an individual nuclei manner without NA network forming.展开更多
In order to search for a more reliable method of sorting fetal nucleated red blood cells (NRBCs) and DNA from maternal peripheral blood and to identify origin of NRBCs and DNA, NRBCs were isolated from peripheral bloo...In order to search for a more reliable method of sorting fetal nucleated red blood cells (NRBCs) and DNA from maternal peripheral blood and to identify origin of NRBCs and DNA, NRBCs were isolated from peripheral blood of 88 pregnant women by density gradient centrifugation and fluorescence activated cell sorter (FACS) respectively. Nested polymerase chain reaction was used to detect normal male SRY gene from blood plasma DNA of 65 pregnant women. The results revealed that fetal NRBCs were found in 14 of 27 maternal samples by density gradient centrifugation. The number of cells was from 1 to 10. Using FACS, CD71 + cells were identified among all 61 samples. The frequency was (0.35±0.25)×10 -2; The detectable rate of the SRY gene of blood plasma DNA from 46 women carrying male fetuses was 65.22 % (30/46). Non-detectable rate for 19 women carrying female fetuses was 94.74 % (18/19). It was concluded that the methods of sorting fetal NRBCs and DNA have already made great progress. The methods for fetal NRBCs and plasma DNA from maternal peripheral blood to diagnose genetic diseases seem to be the best methods of noninvasive prenatal diagnosis.展开更多
The single cell isolation technique was used to detect fetal nucleated erythroblasts at a single cell level from the peripheral blood of pregnant women in order to investigate the feasibility of this method for nonin...The single cell isolation technique was used to detect fetal nucleated erythroblasts at a single cell level from the peripheral blood of pregnant women in order to investigate the feasibility of this method for noninvasive prenatal diagnosis. Single fetal nucleated erythroblasts were isolated from the peripheral blood samples from 51 pregnant women by micromanipulation techniques after density gradient centrifugation. Nested polymerase chain reaction method was used to amplify the SRY gene. It was found that the concordance rate of amplification results with real fetal sex was 82.61 %. The sensitivity and specificity were 80 % and 87.50 % respectively. It was suggested that it is feasible and promising in non invasive prenatal diagnosis to detect fetal nucleated erythroblasts at a single cell level by using micromanipulation techniques.展开更多
An aryl dicarboxylic acid amide compound TMB-5 is an efficient β-form nucleating agent for isotactic polypropylene （iPP）. Because of the solubility of TMB-5, superstructure and morphology of iPP crystals changed wi...An aryl dicarboxylic acid amide compound TMB-5 is an efficient β-form nucleating agent for isotactic polypropylene （iPP）. Because of the solubility of TMB-5, superstructure and morphology of iPP crystals changed with melting conditions. Effects of final heating temperature （Tf） on heterogeneous nucleation of iPP/TMB-5 were investigated. It was discovered that the crystallization temperature increased with decreasing Tf value. The optical microscopic images indicated that when TMB-5 partially dissolved in iPP melt, the remaining （non-dissolved） TMB-5 facilitated the recrystallization of dissolved nucleating agent from the melt, which promoted crystallization. Complete solubility of nucleating agent caused the decreasing efficiency. TMB-5 recrystallized in the form of tiny needles, whose aggregates induced dendritic iPP crystals.展开更多
With the aid of the critical size of colloidal cluster, the critical volume fraction of phase transition of colloidal system is determined by the principle of entropy maximum and Carnahan-Starling （CS） state equatio...With the aid of the critical size of colloidal cluster, the critical volume fraction of phase transition of colloidal system is determined by the principle of entropy maximum and Carnahan-Starling （CS） state equation in this paper. In our discussion, no parameter is introduced externally, and our results are in good agreement with the experimental results.展开更多
Nucleate site distribution plays an essential role in nucleate boiling process. In this paper1 it is pointed out that the size and spatial distribution density of nucleate sites presented on real boiling surface can b...Nucleate site distribution plays an essential role in nucleate boiling process. In this paper1 it is pointed out that the size and spatial distribution density of nucleate sites presented on real boiling surface can be described by the normalized fractal distribution function, and the physical meaning of parameters involved in some experimental correlations proposed by early investigations are identified according to fractal distribution function. It is further suggested that the surface micro geometry characteristics such as the shape of cavities should be described and analyzed qualitatively by using fractal theory.展开更多
In this paper, a fractal model for nucleate pool boiling heat transfer of nanofluids is developed based on the fractal distribution of nanoparticles and nucleation sites on boiling surfaces. The model shows the depend...In this paper, a fractal model for nucleate pool boiling heat transfer of nanofluids is developed based on the fractal distribution of nanoparticles and nucleation sites on boiling surfaces. The model shows the dependences of the heat flux on nanoparticle size and the nanoparticle volume fraction of the suspension, the fractal dimension of the nanoparticle and nucleation site, temperature of nanofluids and properties of fluids. The fractal model predictions show that the natural convection stage continues relatively longer in the case of nanofluids. The addition of nanoparticles causes a decrease of the pool nucleate boiling heat transfer. The nucleate pool boiling heat transfer coefficient is decreased by increasing particle concentration. An excellent agreement between the proposed model predictions and experimental data is found. The validity of the fractal model for nucleate pool boiling heat transfer is thus verified.展开更多
A thermal-hydrodynamic coupling model is used to investigate the interplay between the wall temperature distribution and the bubble departure during the nucleate boiling process.The boiling process is modeled as the c...A thermal-hydrodynamic coupling model is used to investigate the interplay between the wall temperature distribution and the bubble departure during the nucleate boiling process.The boiling process is modeled as the combination of three subprocesses:the transient heat conduction process in the solid heater,the evaporation of the microlayer underneath the bubble,and the bubble dynamics in the two-phase bulk fluid region.The moving bubble interface is captured by the volume of fluid method in the OpenFOAM framework.The proposed model is validated against the experimental results of the boiling process of the water on an Indium Tin Oxide heater.The predicted results agree well with related measurements in the literature.Following the validation,the effects of the boiling heat flux on the bubble departure period are examined.The results show that the bubble departure period decreases with the increase of the applied heat flux.High heat flux will cause irregularity in the departure periods for successive bubbles due to the influence of the wake flow evoked by the rising bubble.Furthermore,the influence of the bubble contact angle on the boiling heat-transfer performance is investigated.It is confirmed that the bubble departure diameter increases with the increase of the contact angle,meanwhile,the average wall temperature decreases with the increase of the contact angle.展开更多
In recently published paper by Yang Chunxin[1], I reexamined the paper. On page 128, the paper 'pointed out that the size and spatial distribution density of nucleation sites presented on real boiling surface can ...In recently published paper by Yang Chunxin[1], I reexamined the paper. On page 128, the paper 'pointed out that the size and spatial distribution density of nucleation sites presented on real boiling surface can be described by the normalized fractal distribution function, and the physical meaning of parameters involved in some experimental correlations proposed by early investigations are identified according to fractal distribution'. However, the definition on fractal dimension given by Yang[1] is highly questionable, and the results obtained by Yang are contradictory to the basic fractal theory. Here are my comments:展开更多
Nucleate boiling is a very efficient method for generating high heat transfer rates from solid surfaces; however, the fundamental physical mechanisms governing nucleate boiling heat transfer are not well understood. T...Nucleate boiling is a very efficient method for generating high heat transfer rates from solid surfaces; however, the fundamental physical mechanisms governing nucleate boiling heat transfer are not well understood. The heat transfer mechanisms around stationary and moving bubbles on very thin microwires were analyzed numerically to evaluate the effect of the bubble motion on the heat transfer from the wire surface. The numerical analysis accurately models the experimentally observed bubble movement and fluid velocities. The analytical model includes the effects of the Marangoni flow around the bubble and the evaporation and condensation within the bubble. The analysis shows that the heat transfer was significantly enhanced by the Marangoni flow around the outside of the bubble which transfers at least twice as much en- ergy from the wire as the heat transfer directly from the wire to the bubble. The enhanced heat transfer due to the Marangoni flow was evident for both stationary and moving bubbles. The moving bubbles also created a wake that further enhanced the heat transfer from the wire. Since the Marangoni number for water is greater than for ethanol for the same conditions, the Marangoni flow and, hence, the bubble velocities are predicted to be greater in water than in ethanol.展开更多
Experimental data and calculated results for the onset of nucleate boiling （ONB） in natural circula- tion systems show that for the same operating conditions, the equilibrium vapor quality for ONB in natural circula...Experimental data and calculated results for the onset of nucleate boiling （ONB） in natural circula- tion systems show that for the same operating conditions, the equilibrium vapor quality for ONB in natural circulation is lower than for forced convections. The differences can be explained using second stir theory. The weak vortices and small stir energy in natural circulation systems result in nucleate boiling occurring earlier than in forced convection systems. In natural circulation systems high mass flow rates are accompa- nied by large kinetic energies and large stir energies, which enables changes in the directions of flow eddies and energy transport. The equilibrium vapor qualities at ONB are then higher at higher mass flow rates. The influence of other flow parameters on ONB can be evaluated by the relationships between these flow pa- rameters and the mass flow rate. The same values can lead to different results due to different eddy direc- tions. This indicates that the quantitative comparability in mathematics cannot be considered as only scien- tific standard. The second stir theory offers a new visual angle for researches on natural circulation.展开更多
In this study, pool boiling test results are provided for the structured enhanced tubes having pores with connecting gaps. The surface geometly of the present tube is similar to that of Turbo-B. Three tubes with diffe...In this study, pool boiling test results are provided for the structured enhanced tubes having pores with connecting gaps. The surface geometly of the present tube is similar to that of Turbo-B. Three tubes with different pore size (0.20 mm, 0.23 mm and 0.27 mm) were manufactured and tested using R-11, R-123 and R-134a. The pore size which yields the maximum heat transfer coefficient varied depending on the refrigerant. For R-134a, the maximum heat transfer coefficient was obtained for the tube having 0.27 nun pore size. For R-11 and R- 123, the optimum pore size was 0.23 mm. One novel feature of the present tubes is that their boiling curves do not show a cross-over characteristic, which existing pored tubes do. The connecting gaps of the present tube are believed to serve an additional route for the liquid supply and delay the dry-out of the tunnel. The present tubes yield the heat transfer coefficients approximately equal to those of the existing pored enhanced tubes. At the heat flux 40 kW/m2 and saturation temperature 4.4° C, the heat transfer coefficients of the present tubes are 6.5 times larger for R-11, 6.0 times larger for R-123 and 5.0 times larger for R-134a than that of the smooth tube展开更多
It is difficult to generate coherent twin boundaries in bulk Al alloys due to their high intrinsic stacking fault energy. Here, we report a strategy to induce high-density growth twins in aluminum alloys through the h...It is difficult to generate coherent twin boundaries in bulk Al alloys due to their high intrinsic stacking fault energy. Here, we report a strategy to induce high-density growth twins in aluminum alloys through the heterogeneous nucleation of twinned Al grains on twin-structured TiC nucleants and the preferred growth of twinned dendrites by laser surface remelting of bulk metals. The solidification structure at the surface shows a mixture of lamellar twinned dendrites with ultra-fine twin boundary spacing (∼2 µm), isolated twinned dendrites, and regular dendrites. EBSD analysis and finite element method (FEM) simulations have been used to understand the competitive growth between twinned and regular dendrites, and the solidification conditions for the preferred growth of twinned dendrites during laser remelting and subsequent rapid solidification are established. It is shown that the reduction in the ratio of temperature gradient G to solidification rate V promotes the formation of lamellar twinned dendrites. The primary trunk spacing of lamellar twinned dendrites is refined by the high thermal gradient and solidification rate. The present work paves a new way to generate high-density growth twins in additive-manufactured Al alloys.展开更多
Due to the low content of alloying elements and the lack of effective nucleation sites,the fusion zone(FZ)of tungsten inert gas(TIG)welded AZ31 alloy typically exhibits undesirable coarse columnar grains,which can res...Due to the low content of alloying elements and the lack of effective nucleation sites,the fusion zone(FZ)of tungsten inert gas(TIG)welded AZ31 alloy typically exhibits undesirable coarse columnar grains,which can result in solidification defects and reduced mechanical properties.In this work,a novel welding wire containing MgO particles has been developed to promote columnar-to-equiaxed transition(CET)in the FZ of TIG-welded AZ31 alloy.The results show the achievement of a fully equiaxed grain structure in the FZ,with a significant 71.9%reduction in grain size to 41 μm from the original coarse columnar dendrites.Furthermore,the combination of using MgO-containing welding wire and pulse current can further refine the grain size to 25.6 μm.Microstructural analyses reveal the homogeneous distribution of MgO particles in the FZ.The application of pulse current results in an increase in the number density of MgO(1-2 μm)from 5.16 × 10^(4) m^(-3) to 6.18 × 10^(4) m^(-3).The good crystallographic matching relationship between MgO and α-Mg matrix,characterized by the orientation relationship of[11(2)0]α-Mg//[0(1)1]MgO and(0002)_(α-Mg)//(111)_(MgO),indicates that the MgO particles can act as effective nucleation sites for α-Mg to reduce nucleation undercooling.According to the Hunt criteria,the critical temperature gradient for CET is greatly enhanced due to the significantly increased number density of MgO nucleation sites.In addition,the correlation with the thermal simulation results reveals a transition in the solidification conditions within the welding pool from the columnar grain zone to the equiaxed grain zone in the CET map,leading to the realization of CET.The exceptional grain refinement has contributed to a simultaneous improvement in the strength and plasticity of welded joints.This study presents a novel strategy for controlling equiaxed microstructure and optimizing mechanical properties in fusion welding or wire and arc additive manufacturing of Mg alloy components.展开更多
Memristive crossbar arrays(MCAs)offer parallel data storage and processing for energy-efficient neuromorphic computing.However,most wafer-scale MCAs that are compatible with complementary metal-oxide-semiconductor(CMO...Memristive crossbar arrays(MCAs)offer parallel data storage and processing for energy-efficient neuromorphic computing.However,most wafer-scale MCAs that are compatible with complementary metal-oxide-semiconductor(CMOS)technology still suffer from substantially larger energy consumption than biological synapses,due to the slow kinetics of forming conductive paths inside the memristive units.Here we report wafer-scale Ag_(2)S-based MCAs realized using CMOS-compatible processes at temperatures below 160℃.Ag_(2)S electrolytes supply highly mobile Ag+ions,and provide the Ag/Ag_(2)S interface with low silver nucleation barrier to form silver filaments at low energy costs.By further enhancing Ag+migration in Ag_(2)S electrolytes via microstructure modulation,the integrated memristors exhibit a record low threshold of approximately−0.1 V,and demonstrate ultra-low switching-energies reaching femtojoule values as observed in biological synapses.The low-temperature process also enables MCA integration on polyimide substrates for applications in flexible electronics.Moreover,the intrinsic nonidealities of the memristive units for deep learning can be compensated by employing an advanced training algorithm.An impressive accuracy of 92.6%in image recognition simulations is demonstrated with the MCAs after the compensation.The demonstrated MCAs provide a promising device option for neuromorphic computing with ultra-high energy-efficiency.展开更多
基金Century Programme of Chinese Academy of Sciences.
文摘Heat transfer coefficients in nucleate pool boiling were measured on a horizontal copper surface for refrigerants, HFC-134a, HFC-32, and HFC-125, their binary and ternary mixtures under saturated conditions at 0.9MPa. Compared to pure components, both binary and ternary mixtures showed lower heat transfer coefficients.This deterioration was more pronounced as heat flux was increased. Experimental data were compared with some empirical and semi-empirical correlations available in literature. For binary mixture, the accuracy of the correlations varied considerably with mixtures and the heat flux. Experimental data for HFC-32/134a/125 were also compared with available correlated equation obtained by Thome. For ternary mixture, the boiling range of binary mixture composed by the pure fluids with the lowest and the medium boiling points, and their concentration difference had important effects on boiling heat transfer coefficients.
文摘A novel kind of multi-core magnetic composite particles, the surfaces of which were respectively mo- dified with goat-anti-mouse IgG and antitransferrin receptor（anti-CD71）, was prepared. The fetal nucleated red blood cells（FNRBCs） in the peripheral blood of a gravida were rapidly and effectively enriched and separated by the mo- dified multi-core magnetic composite particles in an external magnetic field. The obtained FNRBCs were used for the identification of the fetal sex by means of fluorescence in situ hybridization（FISH） technique. The results demonstrate that the multi-core magnetic composite particles meet the requirements for the enrichment and speration of FNRBCs with a low concentration and the accuracy of detetion for the diagnosis of fetal sex reached to 95%. Moreover, the obtained FNRBCs were applied to the non-invasive diagnosis of Down syndrome and chromosome 3p21 was de- tected. The above facts indicate that the novel multi-core magnetic composite particles-based method is simple, relia- ble and cost-effective and has opened up vast vistas for the potential application in clinic non-invasive prenatal diag- nosis.
文摘This paper presents results of an experimental investigation carried out to determine the effects of surface material on nucleate pool boiling heat transfer of refrigerant R113. Experiments were performed on horizontal circular plates of brass, copper and aluminum. The heat transfer coefficient was evaluated by measuring wall superheat and effective heat flux removed by boiling. The experiments were carried out in the heat flux range of 8 to 200 kW/m2. The obtained results have shown significant effect of surface material, with copper providing the highest heat transfer coefficient among the samples, and aluminum the least. There was negligible difference at low heat fluxes, but copper showed 23% better performance at high heat fluxes than aluminum and 18% better than brass.
文摘To find a simple, effective method of isolating fetal cells from maternal peripheral blood for prenatal diagnosis, 45 women were studied with their gestation being 6-14 weeks and age 21- 30 years. The fetal cells were isolated from maternal blood by using discontinuous density gradient centrifugation. Some of the isolated cells were made smear and counted under the microscope; others were used for predicting fetal sex by PCR amplification of Y chromosome specific DYZ1 gene. The major cells in the upper separation interface were lymphocytes and monocytes, with occasionally seen nucleated red blood cells (NRBC); while those in the middle separation interface were neutrocytes, with NRBC scattering. The ratio of NRBC/nucleated cells was 1. 98±0. 28× 10-5. There was no significant difference between the first and second trimester (P>0. 05). The amount of isolated fetal cells was sufficient for prenatal genetic diagnosis. Male pregnancy was correctly predicted in 10 out of 13 cases. It is concluded that the method of discontinuous density gradient centrifugation was of considerable importance in the development of non-invasive prenatal genetic diagnosis.
文摘Based on the tests of more than ten different additives, several effective additives are found capable of improving the boiling heat transfer behavior of water pronouncedly. The mechanism of the enhancement of nucleate boiling with additives has been investigated, and the results indicate that one of the important reasons is that the nucleation sites have been increased.
基金financially supported by the National Natural Science Foundation of China(Nos.21034005,50903048)
文摘The effect of clay on the nucleating behavior of 1,3：2,4-bis（3,4-dimethylbenzylidene） sorbitol （DMDBS） in cryatallization of isotactic polypropylene （iPP） was investigated by means of differential scanning calorimetry （DSC）, dynamic rheology and polarized light microscopy （PLM）. It is interesting to note that the incorporation of layered clay nanoparticles into DMDBS-nucleated iPP may induce a synergetic nucleation effect while the DMDBS content is below 0.1 wt%, otherwise it restricts the crystallization rate prominently as the DMDBS content increases up to 0.3 wt%, which has exceeded the content threshold to yield a nucleating agent （NA） network. As shown by dynamic rheological investigations, the clay nanoparticles demonstrate an obstructive effect of disturbing the consistency of DMDBS fibrils network. Moreover, to further demonstrate the importance of NA network formation in the crystallization of iPP, we used another NA named HPN-20e, which can not form network structure at all over the concentration studied, for comparison. In this case, the nucleated-crystallization rate is independent on the addition of clay nanoparticles, as the nucleating mechanism is an individual nuclei manner without NA network forming.
文摘In order to search for a more reliable method of sorting fetal nucleated red blood cells (NRBCs) and DNA from maternal peripheral blood and to identify origin of NRBCs and DNA, NRBCs were isolated from peripheral blood of 88 pregnant women by density gradient centrifugation and fluorescence activated cell sorter (FACS) respectively. Nested polymerase chain reaction was used to detect normal male SRY gene from blood plasma DNA of 65 pregnant women. The results revealed that fetal NRBCs were found in 14 of 27 maternal samples by density gradient centrifugation. The number of cells was from 1 to 10. Using FACS, CD71 + cells were identified among all 61 samples. The frequency was (0.35±0.25)×10 -2; The detectable rate of the SRY gene of blood plasma DNA from 46 women carrying male fetuses was 65.22 % (30/46). Non-detectable rate for 19 women carrying female fetuses was 94.74 % (18/19). It was concluded that the methods of sorting fetal NRBCs and DNA have already made great progress. The methods for fetal NRBCs and plasma DNA from maternal peripheral blood to diagnose genetic diseases seem to be the best methods of noninvasive prenatal diagnosis.
基金This project was supported by a grant from Science Foun-dation of Ministry of Public Heath of China (No. 96 .2 - 112 )and a grant from Hubei Provincial National Natural ScienceFoundation(96 J0 6 8)
文摘The single cell isolation technique was used to detect fetal nucleated erythroblasts at a single cell level from the peripheral blood of pregnant women in order to investigate the feasibility of this method for noninvasive prenatal diagnosis. Single fetal nucleated erythroblasts were isolated from the peripheral blood samples from 51 pregnant women by micromanipulation techniques after density gradient centrifugation. Nested polymerase chain reaction method was used to amplify the SRY gene. It was found that the concordance rate of amplification results with real fetal sex was 82.61 %. The sensitivity and specificity were 80 % and 87.50 % respectively. It was suggested that it is feasible and promising in non invasive prenatal diagnosis to detect fetal nucleated erythroblasts at a single cell level by using micromanipulation techniques.
文摘An aryl dicarboxylic acid amide compound TMB-5 is an efficient β-form nucleating agent for isotactic polypropylene （iPP）. Because of the solubility of TMB-5, superstructure and morphology of iPP crystals changed with melting conditions. Effects of final heating temperature （Tf） on heterogeneous nucleation of iPP/TMB-5 were investigated. It was discovered that the crystallization temperature increased with decreasing Tf value. The optical microscopic images indicated that when TMB-5 partially dissolved in iPP melt, the remaining （non-dissolved） TMB-5 facilitated the recrystallization of dissolved nucleating agent from the melt, which promoted crystallization. Complete solubility of nucleating agent caused the decreasing efficiency. TMB-5 recrystallized in the form of tiny needles, whose aggregates induced dendritic iPP crystals.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 10375024 and 10775018)the Science Foundation of Hunan Educational Committee of China (Grant Nos. 08B028 and 06B057)the Natural Science Foundation of Hunan Province of China (Grant No. 08jj6043)
文摘With the aid of the critical size of colloidal cluster, the critical volume fraction of phase transition of colloidal system is determined by the principle of entropy maximum and Carnahan-Starling （CS） state equation in this paper. In our discussion, no parameter is introduced externally, and our results are in good agreement with the experimental results.
文摘Nucleate site distribution plays an essential role in nucleate boiling process. In this paper1 it is pointed out that the size and spatial distribution density of nucleate sites presented on real boiling surface can be described by the normalized fractal distribution function, and the physical meaning of parameters involved in some experimental correlations proposed by early investigations are identified according to fractal distribution function. It is further suggested that the surface micro geometry characteristics such as the shape of cavities should be described and analyzed qualitatively by using fractal theory.
基金Supported by the Scientific Research Special Foundation of Provincial University of Education Department of Fujian Province, China (Grant No.JK2009039)Sanming University (Grant No. HX200804)
文摘In this paper, a fractal model for nucleate pool boiling heat transfer of nanofluids is developed based on the fractal distribution of nanoparticles and nucleation sites on boiling surfaces. The model shows the dependences of the heat flux on nanoparticle size and the nanoparticle volume fraction of the suspension, the fractal dimension of the nanoparticle and nucleation site, temperature of nanofluids and properties of fluids. The fractal model predictions show that the natural convection stage continues relatively longer in the case of nanofluids. The addition of nanoparticles causes a decrease of the pool nucleate boiling heat transfer. The nucleate pool boiling heat transfer coefficient is decreased by increasing particle concentration. An excellent agreement between the proposed model predictions and experimental data is found. The validity of the fractal model for nucleate pool boiling heat transfer is thus verified.
基金the National Key Research and Development Program of China(Grant No.2013GB113005B)the the National Natural Science Foundation of China(Grant No.51976026)。
文摘A thermal-hydrodynamic coupling model is used to investigate the interplay between the wall temperature distribution and the bubble departure during the nucleate boiling process.The boiling process is modeled as the combination of three subprocesses:the transient heat conduction process in the solid heater,the evaporation of the microlayer underneath the bubble,and the bubble dynamics in the two-phase bulk fluid region.The moving bubble interface is captured by the volume of fluid method in the OpenFOAM framework.The proposed model is validated against the experimental results of the boiling process of the water on an Indium Tin Oxide heater.The predicted results agree well with related measurements in the literature.Following the validation,the effects of the boiling heat flux on the bubble departure period are examined.The results show that the bubble departure period decreases with the increase of the applied heat flux.High heat flux will cause irregularity in the departure periods for successive bubbles due to the influence of the wake flow evoked by the rising bubble.Furthermore,the influence of the bubble contact angle on the boiling heat-transfer performance is investigated.It is confirmed that the bubble departure diameter increases with the increase of the contact angle,meanwhile,the average wall temperature decreases with the increase of the contact angle.
文摘In recently published paper by Yang Chunxin[1], I reexamined the paper. On page 128, the paper 'pointed out that the size and spatial distribution density of nucleation sites presented on real boiling surface can be described by the normalized fractal distribution function, and the physical meaning of parameters involved in some experimental correlations proposed by early investigations are identified according to fractal distribution'. However, the definition on fractal dimension given by Yang[1] is highly questionable, and the results obtained by Yang are contradictory to the basic fractal theory. Here are my comments:
基金Supported by the National Natural Science Foundation of China (No. 50476014)
文摘Nucleate boiling is a very efficient method for generating high heat transfer rates from solid surfaces; however, the fundamental physical mechanisms governing nucleate boiling heat transfer are not well understood. The heat transfer mechanisms around stationary and moving bubbles on very thin microwires were analyzed numerically to evaluate the effect of the bubble motion on the heat transfer from the wire surface. The numerical analysis accurately models the experimentally observed bubble movement and fluid velocities. The analytical model includes the effects of the Marangoni flow around the bubble and the evaporation and condensation within the bubble. The analysis shows that the heat transfer was significantly enhanced by the Marangoni flow around the outside of the bubble which transfers at least twice as much en- ergy from the wire as the heat transfer directly from the wire to the bubble. The enhanced heat transfer due to the Marangoni flow was evident for both stationary and moving bubbles. The moving bubbles also created a wake that further enhanced the heat transfer from the wire. Since the Marangoni number for water is greater than for ethanol for the same conditions, the Marangoni flow and, hence, the bubble velocities are predicted to be greater in water than in ethanol.
基金Supported by the National Natural Science Foundation of China(No. 50976033)the National Key Laboratory of Bubble Physicsand Natural Circulation Funds
文摘Experimental data and calculated results for the onset of nucleate boiling （ONB） in natural circula- tion systems show that for the same operating conditions, the equilibrium vapor quality for ONB in natural circulation is lower than for forced convections. The differences can be explained using second stir theory. The weak vortices and small stir energy in natural circulation systems result in nucleate boiling occurring earlier than in forced convection systems. In natural circulation systems high mass flow rates are accompa- nied by large kinetic energies and large stir energies, which enables changes in the directions of flow eddies and energy transport. The equilibrium vapor qualities at ONB are then higher at higher mass flow rates. The influence of other flow parameters on ONB can be evaluated by the relationships between these flow pa- rameters and the mass flow rate. The same values can lead to different results due to different eddy direc- tions. This indicates that the quantitative comparability in mathematics cannot be considered as only scien- tific standard. The second stir theory offers a new visual angle for researches on natural circulation.
基金theR &D Management Center for Energy and Resources ofKorea
文摘In this study, pool boiling test results are provided for the structured enhanced tubes having pores with connecting gaps. The surface geometly of the present tube is similar to that of Turbo-B. Three tubes with different pore size (0.20 mm, 0.23 mm and 0.27 mm) were manufactured and tested using R-11, R-123 and R-134a. The pore size which yields the maximum heat transfer coefficient varied depending on the refrigerant. For R-134a, the maximum heat transfer coefficient was obtained for the tube having 0.27 nun pore size. For R-11 and R- 123, the optimum pore size was 0.23 mm. One novel feature of the present tubes is that their boiling curves do not show a cross-over characteristic, which existing pored tubes do. The connecting gaps of the present tube are believed to serve an additional route for the liquid supply and delay the dry-out of the tunnel. The present tubes yield the heat transfer coefficients approximately equal to those of the existing pored enhanced tubes. At the heat flux 40 kW/m2 and saturation temperature 4.4° C, the heat transfer coefficients of the present tubes are 6.5 times larger for R-11, 6.0 times larger for R-123 and 5.0 times larger for R-134a than that of the smooth tube
基金supported by the National Natural Science Foundation of China(grant no.52371029)the Science and Technology Development Program of Jilin Province,China(grant no.20210402083GH).
文摘It is difficult to generate coherent twin boundaries in bulk Al alloys due to their high intrinsic stacking fault energy. Here, we report a strategy to induce high-density growth twins in aluminum alloys through the heterogeneous nucleation of twinned Al grains on twin-structured TiC nucleants and the preferred growth of twinned dendrites by laser surface remelting of bulk metals. The solidification structure at the surface shows a mixture of lamellar twinned dendrites with ultra-fine twin boundary spacing (∼2 µm), isolated twinned dendrites, and regular dendrites. EBSD analysis and finite element method (FEM) simulations have been used to understand the competitive growth between twinned and regular dendrites, and the solidification conditions for the preferred growth of twinned dendrites during laser remelting and subsequent rapid solidification are established. It is shown that the reduction in the ratio of temperature gradient G to solidification rate V promotes the formation of lamellar twinned dendrites. The primary trunk spacing of lamellar twinned dendrites is refined by the high thermal gradient and solidification rate. The present work paves a new way to generate high-density growth twins in additive-manufactured Al alloys.
基金supported by the National Natural Science Foundation of China(No.51871155).
文摘Due to the low content of alloying elements and the lack of effective nucleation sites,the fusion zone(FZ)of tungsten inert gas(TIG)welded AZ31 alloy typically exhibits undesirable coarse columnar grains,which can result in solidification defects and reduced mechanical properties.In this work,a novel welding wire containing MgO particles has been developed to promote columnar-to-equiaxed transition(CET)in the FZ of TIG-welded AZ31 alloy.The results show the achievement of a fully equiaxed grain structure in the FZ,with a significant 71.9%reduction in grain size to 41 μm from the original coarse columnar dendrites.Furthermore,the combination of using MgO-containing welding wire and pulse current can further refine the grain size to 25.6 μm.Microstructural analyses reveal the homogeneous distribution of MgO particles in the FZ.The application of pulse current results in an increase in the number density of MgO(1-2 μm)from 5.16 × 10^(4) m^(-3) to 6.18 × 10^(4) m^(-3).The good crystallographic matching relationship between MgO and α-Mg matrix,characterized by the orientation relationship of[11(2)0]α-Mg//[0(1)1]MgO and(0002)_(α-Mg)//(111)_(MgO),indicates that the MgO particles can act as effective nucleation sites for α-Mg to reduce nucleation undercooling.According to the Hunt criteria,the critical temperature gradient for CET is greatly enhanced due to the significantly increased number density of MgO nucleation sites.In addition,the correlation with the thermal simulation results reveals a transition in the solidification conditions within the welding pool from the columnar grain zone to the equiaxed grain zone in the CET map,leading to the realization of CET.The exceptional grain refinement has contributed to a simultaneous improvement in the strength and plasticity of welded joints.This study presents a novel strategy for controlling equiaxed microstructure and optimizing mechanical properties in fusion welding or wire and arc additive manufacturing of Mg alloy components.
基金supported by the Swedish Strategic Research Foundation(SSF FFL15-0174 to Zhen Zhang)the Swedish Research Council(VR 2018-06030 and 2019-04690 to Zhen Zhang)+1 种基金the Wallenberg Academy Fellow Extension Program(KAW 2020-0190 to Zhen Zhang)the Olle Engkvist Foundation(Postdoc grant 214-0322 to Zhen Zhang).
文摘Memristive crossbar arrays(MCAs)offer parallel data storage and processing for energy-efficient neuromorphic computing.However,most wafer-scale MCAs that are compatible with complementary metal-oxide-semiconductor(CMOS)technology still suffer from substantially larger energy consumption than biological synapses,due to the slow kinetics of forming conductive paths inside the memristive units.Here we report wafer-scale Ag_(2)S-based MCAs realized using CMOS-compatible processes at temperatures below 160℃.Ag_(2)S electrolytes supply highly mobile Ag+ions,and provide the Ag/Ag_(2)S interface with low silver nucleation barrier to form silver filaments at low energy costs.By further enhancing Ag+migration in Ag_(2)S electrolytes via microstructure modulation,the integrated memristors exhibit a record low threshold of approximately−0.1 V,and demonstrate ultra-low switching-energies reaching femtojoule values as observed in biological synapses.The low-temperature process also enables MCA integration on polyimide substrates for applications in flexible electronics.Moreover,the intrinsic nonidealities of the memristive units for deep learning can be compensated by employing an advanced training algorithm.An impressive accuracy of 92.6%in image recognition simulations is demonstrated with the MCAs after the compensation.The demonstrated MCAs provide a promising device option for neuromorphic computing with ultra-high energy-efficiency.
