BACKGROUND Total hip arthroplasty is a safe and effective procedure.To improve survivorship,ultrahigh molecular weight polyethylene hip liners with antioxidants have been developed.Additive antioxidant was deployed to...BACKGROUND Total hip arthroplasty is a safe and effective procedure.To improve survivorship,ultrahigh molecular weight polyethylene hip liners with antioxidants have been developed.Additive antioxidant was deployed to reduce oxidation and consequential wear,loosening,or osteolysis.A unique manufacturing process was utilized for two such hip liners,the Novation®and Alteon®XLE hip liners and this research represents the first large series on this specific material.The study hypothesis was that Novation and Alteon XLE hip liners have similar short-term survivorship as other manufacturers’antioxidant liners according to procedure and outcome data from the American Joint Replacement Registry(AJRR).AIM To demonstrate similar short-term survivorship of XLE antioxidant hip liners compared to all antioxidant hip liners in AJRR.METHODS Utilizing total hip arthroplasty data from the AJRR,a retrospective review was performed for subjects who underwent implantation of Novation XLE(n=461),Alteon XLE(n=989),or any other antioxidant hip liner(termed the aggregate antioxidant group;n=39964)as of March 31,2022.Survivorship at three years and revision rates were compared statistically between the Novation group and the aggregate antioxidant group as well as the Alteon group and the aggregate antioxidant group.RESULTS Survivorship at three years post-surgery was 99.09%for Novation,97.73%for Alteon,and 97.69%for the aggregate antioxidant group.There were no reports of failure due to wear in either the Novation or Alteon groups.Among the revision categories(fracture,infection,aseptic loosening,instability,mechanical complications,wear,pain,hematoma/wound complications,or other),there were no significant differences identified in either comparison.There were also no significant differences in cumulative percent revision rates up to three years post-surgery for the Novation vs aggregate antioxidant group or the Alteon vs aggregate antioxidant group.CONCLUSION Novation and Alteon XLE hip liner revision rate and survivorship are equivalent to other antioxidant hip liners in the short term.展开更多
The research progress and major achievements on genetic breeding, het- erosis utilization of rapeseed in Henan Province were summarized, with the aim to provide technical guidance for rapeseed genetic breeding in the ...The research progress and major achievements on genetic breeding, het- erosis utilization of rapeseed in Henan Province were summarized, with the aim to provide technical guidance for rapeseed genetic breeding in the future work. Faced with the problems of lack of special varieties, highly demand for healthy oil and high production cost in rapeseed production in recent years, the breeding goals of rapeseed have been adjusted from high yield, high quality and disease resistance to high oil, high oleic acid, adaptative to mechanization, late planting resistance. The breeding technologies mainly focused on the isolated microspore culture, molecular marker assisted selection, and the corresponding high efficiency technical systems were constructed. The innovative research on excellent germplasm resources were carried on, which created and established breeding populations and distinctive new germplasm resources with diverse variations such as high oil content, high oleic acid content and low linolenic acid, cold resistance, drought resistance, pod shatter resistance and different flower color variations. A series of rapeseed hybrids of dou- ble low varieties with strong heterosis and high oil contents were released and these hybrids significantly improved seed yield, quality and resistance. The average yield of rapeseed in Henan Province was 22.49% higher than the national average yield in 2003-2015. All of the achievements provided strong technical support for the upgrading of rapeseed varieties and increasing both production and income.展开更多
文摘BACKGROUND Total hip arthroplasty is a safe and effective procedure.To improve survivorship,ultrahigh molecular weight polyethylene hip liners with antioxidants have been developed.Additive antioxidant was deployed to reduce oxidation and consequential wear,loosening,or osteolysis.A unique manufacturing process was utilized for two such hip liners,the Novation®and Alteon®XLE hip liners and this research represents the first large series on this specific material.The study hypothesis was that Novation and Alteon XLE hip liners have similar short-term survivorship as other manufacturers’antioxidant liners according to procedure and outcome data from the American Joint Replacement Registry(AJRR).AIM To demonstrate similar short-term survivorship of XLE antioxidant hip liners compared to all antioxidant hip liners in AJRR.METHODS Utilizing total hip arthroplasty data from the AJRR,a retrospective review was performed for subjects who underwent implantation of Novation XLE(n=461),Alteon XLE(n=989),or any other antioxidant hip liner(termed the aggregate antioxidant group;n=39964)as of March 31,2022.Survivorship at three years and revision rates were compared statistically between the Novation group and the aggregate antioxidant group as well as the Alteon group and the aggregate antioxidant group.RESULTS Survivorship at three years post-surgery was 99.09%for Novation,97.73%for Alteon,and 97.69%for the aggregate antioxidant group.There were no reports of failure due to wear in either the Novation or Alteon groups.Among the revision categories(fracture,infection,aseptic loosening,instability,mechanical complications,wear,pain,hematoma/wound complications,or other),there were no significant differences identified in either comparison.There were also no significant differences in cumulative percent revision rates up to three years post-surgery for the Novation vs aggregate antioxidant group or the Alteon vs aggregate antioxidant group.CONCLUSION Novation and Alteon XLE hip liner revision rate and survivorship are equivalent to other antioxidant hip liners in the short term.
基金Supported by the Key Scientific and Technological Project of Henan Province(151100111200)the National Natural Science Foundation of China(31271763)the China Agriculture Research System(CARS-13)~~
文摘The research progress and major achievements on genetic breeding, het- erosis utilization of rapeseed in Henan Province were summarized, with the aim to provide technical guidance for rapeseed genetic breeding in the future work. Faced with the problems of lack of special varieties, highly demand for healthy oil and high production cost in rapeseed production in recent years, the breeding goals of rapeseed have been adjusted from high yield, high quality and disease resistance to high oil, high oleic acid, adaptative to mechanization, late planting resistance. The breeding technologies mainly focused on the isolated microspore culture, molecular marker assisted selection, and the corresponding high efficiency technical systems were constructed. The innovative research on excellent germplasm resources were carried on, which created and established breeding populations and distinctive new germplasm resources with diverse variations such as high oil content, high oleic acid content and low linolenic acid, cold resistance, drought resistance, pod shatter resistance and different flower color variations. A series of rapeseed hybrids of dou- ble low varieties with strong heterosis and high oil contents were released and these hybrids significantly improved seed yield, quality and resistance. The average yield of rapeseed in Henan Province was 22.49% higher than the national average yield in 2003-2015. All of the achievements provided strong technical support for the upgrading of rapeseed varieties and increasing both production and income.
