Biodiesel industrial production based on a solid base catalyst in a fixed-bed was simulated. The lab and bench scale experiments were carded out effectively, in which the kinetic model is established and it can descri...Biodiesel industrial production based on a solid base catalyst in a fixed-bed was simulated. The lab and bench scale experiments were carded out effectively, in which the kinetic model is established and it can describe the transesterification reaction well. The Antoine equation of biodiesel is regressed with the vapor-liquid data cited of literature. The non-random two liquid （NRTL） model is applied to describe the system of fatty acid methyl ester （FAME）, methanol and glycerol and parameters are obtained. The Ternary phase map is obtained from Aspen Plus via the liquid-liquid equilibrium （LLE） data. In order to describe the production in a fixed-bed performs in industrial scale after being magnified 1 000 times, the Aspen Plus simulation is employed, where two flowsheets are simulated to predict material and energy consumption. The simulation results prove that at least 350. 42 kW energy consumption can be reduced per hour to produce per ton biodiesel compared with data reported in previous references.展开更多
For extra-low permeability reservoirs, with a permeability of about 0.3×10?3 μm2, fluid flow and production performance in cores were studied. A long core holder with a multi-location piezometric measurement was...For extra-low permeability reservoirs, with a permeability of about 0.3×10?3 μm2, fluid flow and production performance in cores were studied. A long core holder with a multi-location piezometric measurement was specially designed. An artificial long core, about 700 mm long and with a cross section of 45mm×45mm, was used. In the experiment, pressure distribution along the core can be measured in real time. Single phase flow in the core was investigated. Different modes of production in long cores were also simulated including natural depletion, water flooding, and advanced water flooding. Through physical simulation, flow parameters were collected and production characteristics in extra-low permeability cores were studied. From experimental results, it can be seen that fluid flow in extra-low permeability cores is different from that in high permeability cores. Transmission of pressure in extra-low permeability cores is very slow, and it needs a long time for the pressure to become stable. The distribution curve of pressure along the core is nonlinear and the production rate in extra-low permeability reservoirs decreases sharply. The development effects of different production modes in extra-low permeability cores were compared with one another. Among the production modes, advanced water flooding has much potential for effective development of extra-low permeability reservoirs. Natural depletion and conventional water flooding can also be used in early production periods. In addition, the countermeasures and some ideas especially for the potential development of extra-low permeability reservoirs are suggested.展开更多
Based on the casting manufacture practice of steel slabs by CSP technology, the flow and the temperature fields of the funnel mould and the secondary cooling segment were simulated using the commercial code, CFX4. Com...Based on the casting manufacture practice of steel slabs by CSP technology, the flow and the temperature fields of the funnel mould and the secondary cooling segment were simulated using the commercial code, CFX4. Compared with other physical investigations, the correlative data of the present simulation results are in good agreement with them. Therefore, a more comprehensive survey for metallurgy characteristic of the flow and the temperature fields in CSP continuous casting process can be achieved.展开更多
The bioactive constituents found in natural products(NPs)are crucial in protein-ligand interactions and drug discovery.However,it is difficult to identify ligand molecules from complex NPs that specifically bind to ta...The bioactive constituents found in natural products(NPs)are crucial in protein-ligand interactions and drug discovery.However,it is difficult to identify ligand molecules from complex NPs that specifically bind to target protein,which often requires time-consuming and labor-intensive processes such as isolation and enrichment.To address this issue,in this study we developed a method that combines ultra-high performance liquid chromatography-electrospray ionization-mass spectrometry(UHPLCESI-MS)with molecular dynamics(MD)simulation to identify and observe,rapidly and efficiently,the bioactive components in NPs that bind to specific protein target.In this method,a specific protein target was introduced online using a three-way valve to form a protein-ligand complex.The complex was then detected in real time using high-resolution MS to identify potential ligands.Based on our method,only 10 molecules from green tea(a representative natural product),including the commonly reported epigallocatechin gallate(EGCG)and epicatechin gallate(ECG),as well as the previously unreported eepicatechin(4β→8)-epigallocatechin 3-O-gallate(EC-EGCG)and eepiafzelechin 3-O-gallate-(4β→8)-epigallocatechin 3-O-gallate(EFG-EGCG),were screened out,which could form complexes with Aβ_(1-42)(a representative protein target),and could be potential ligands of Aβ_(1-42).Among of them,EC-EGCG demonstrated the highest binding free energy with Aβ_(1-42)(−68.54±3.82 kcal/mol).On the other side,even though the caffeine had the highest signal among green tea extracts,it was not observed to form a complex with Aβ_(1-42).Compared to other methods such as affinity selection mass spectrometry(ASMS)and native MS,our method is easy to operate and interpret the data.Undoubtedly,it provides a new methodology for potential drug discovery in NPs,and will accelerate the research on screening ligands for specific proteins from complex NPs.展开更多
Gas production from multiple coal seams has become common practice in many coal basins around the world. Although gas production rates are typically enhanced, the economic viability of such practice is not well studie...Gas production from multiple coal seams has become common practice in many coal basins around the world. Although gas production rates are typically enhanced, the economic viability of such practice is not well studied. In order to investigate the technical and economic feasibility of multiple coal seams production, reservoir simulation integrated with economics modelling was performed to study the effect of important reservoir properties of the secondary coal seam on production and economic performance using both vertical and horizontal wells. The results demonstrated that multiple seam gas production of using both vertical and horizontal wells have competitive advantage over single layer production under most scenarios. Gas content and permeability of the secondary coal seam are the most important reservoir properties that have impact on the economic feasibility of multiple seam gas production. The comparison of vertical well and horizontal well performance showed that horizontal well is more economically attractive for both single well and gas field. Moreover, wellhead price is the most sensitive to the economic performance, followed by operating costs and government subsidy. Although the results of reservoir simulation combined with economic analysis are subject to assumptions, multiple seam gas production is more likely to maintain profitability compared with single layer production.展开更多
The production and energy coupling system is used to mainly present energy flow, material flow, information flow, and their coupling interaction. Through the modeling and simulation of this system, the performance of ...The production and energy coupling system is used to mainly present energy flow, material flow, information flow, and their coupling interaction. Through the modeling and simulation of this system, the performance of energy flow can be analyzed and optimized in the process industry. In order to study this system, the component based hybrid Petri net methodology (CpnHPN) is proposed, synthesizing a number of extended Petri net methods and using the concept of energy place, material place, and information place. Through the interface place in CpnHPN, the component based encapsulation is established, which enables the production and energy coupling system to be built, analyzed, and optimized on the multi-level framework. Considering the block and brief simulation for hybrid system, the CpnHPN model is simulated with Simulink/Stateflow. To illustrate the use of the proposed methodology, the application of CpnHPN in the energy optimization of chlorine balance system is provided.展开更多
It is practical, economic and sometimes essential to derive rules or conclusions by performing lesser runs of experiments. In this part, a methodology based on 2 f factorial design was brought up to derive guidelines ...It is practical, economic and sometimes essential to derive rules or conclusions by performing lesser runs of experiments. In this part, a methodology based on 2 f factorial design was brought up to derive guidelines to simulate growth curve and production of sugars by Spirulina (Arthrospira) maxima . The growth curve or accumulation process of sugars was idealized by sets of straight lines limited by phase transfers of growth or accumulation of sugars. Normal analyses of the critical values of the transfers were used to derive their linear relationships with the initial conditions of the experimental factors. These linear functions were called guidelines and were used to simulate the growth curve or accumulation of sugars. Generalization of the guideline technique was determined by the kinetic limitation of nutrient nitrogen or sulfur that was dependent upon their stoichiometric deficiency directly derived from their initial values in the medium. This method uses the initial conditions of culture and does not need measurements of concentrations of nitrate, sulfate and pigments during cultivation. It is a practical and useful alternative way to trace and predict approximately the growth curve and production of sugars by S. maxima .展开更多
The article established the HDRICE model by modifying the structure of the ORYZA1 model and revising its parameters by field experiments. The HDRICE model consists of the modules of morphological development of rice, ...The article established the HDRICE model by modifying the structure of the ORYZA1 model and revising its parameters by field experiments. The HDRICE model consists of the modules of morphological development of rice, daily dry matter accumulation and partitioning, daily CO2 assimilation of the canopy, leaf area, and tiller development. The model preferably simulated the dynamic rice development because of the thorough integration of the effects of temperature and light on the rates of rice development, photosynthesis, respiration, and. other ecophysiological processes. In addition, this model has attainable grain yield in the test experiment that showed the potential yield of cultivar Xieyou 46 ranged from 11 to 13 tons ha-~. Besides, the model was used to optimize the combinations of the transplanting date, seedling age and density for cultivar Xieyou 46 at Jinhua area, and the population quantitative indices to attain the potential yield such as maximum stems, effective panicles, filled grain number/leaf area, and so on. The result showed that the combination of transplanting date on July 25, seedling age of 35 days and base seedling density of 1.33 x 106ha-1 is the optimum combination for the second hybrid rice production in Jinhua County, China. And the maximum stems, the effective panicles, the filled grain per panicle, the peak of optimum LAI, LAI in later filling stage, and the filled grain number/leaf were 6.03×10^6ha, 3.99×10^6ha, 119.2, 8.59, 5-6, and 0.64, respectively.展开更多
Due to the variable output of renewable energy (RE) generation, difficulties of dispatching RE for power system operators could not be avoided. One of possible solutions is the energy storage technology, especially th...Due to the variable output of renewable energy (RE) generation, difficulties of dispatching RE for power system operators could not be avoided. One of possible solutions is the energy storage technology, especially the battery storage system. The large-scale energy storage system is available to support power system reliable flexibility for load following and system frequency regulation. In this paper, the bottlenecks of large-scale solar power generation dispatching and operation in Qinghai grid are discussed, and a new PV-energy storage coordinated dispatching method is proposed for reduction of PV curtailment in Qinghai. Moreover, the validation based on the time-series production simulation is provided using real data from Qinghai. The results indicate that the proposed method can effectively decrease the curtailment of solar power and future vision of large-scale solar power coordinated operation with energy storage system is also presented.展开更多
Based on the independently developed true triaxial multi-physical field large-scale physical simulation system of in-situ injection and production,we conducted physical simulation of long-term multi-well injection and...Based on the independently developed true triaxial multi-physical field large-scale physical simulation system of in-situ injection and production,we conducted physical simulation of long-term multi-well injection and production in the hot dry rocks of the Gonghe Basin,Qinghai Province,NW China.Through multi-well connectivity experiments,the spatial distribution characteristics of the natural fracture system in the rock samples and the connectivity between fracture and wellbore were clarified.The injection and production wells were selected to conduct the experiments,namely one injection well and two production wells,one injection well and one production well.The variation of several physical parameters in the production well was analyzed,such as flow rate,temperature,heat recovery rate and fluid recovery.The results show that under the combination of thermal shock and injection pressure,the fracture conductivity was enhanced,and the production temperature showed a downward trend.The larger the flow rate,the faster the decrease.When the local closed area of the fracture was gradually activated,new heat transfer areas were generated,resulting in a lower rate of increase or decrease in the mining temperature.The heat recovery rate was mainly controlled by the extraction flow rate and the temperature difference between injection and production fluid.As the conductivity of the leak-off channel increased,the fluid recovery of the production well rapidly decreased.The influence mechanisms of dominant channels and fluid leak-off on thermal recovery performance are different.The former limits the heat exchange area,while the latter affects the flow rate of the produced fluid.Both of them are important factors affecting the long-term and efficient development of hot dry rock.展开更多
The distributions of local velocity and local phase holdup along the radial direction of pipes are complicated because of gravity differentiation,and the distribution of fluid velocity fi eld changes along the gravity...The distributions of local velocity and local phase holdup along the radial direction of pipes are complicated because of gravity differentiation,and the distribution of fluid velocity fi eld changes along the gravity direction in horizontal wells.Therefore,measuring the mixture flow and water holdup is difficult,resulting in poor interpretation accuracy of the production logging output profile.In this paper,oil–water two-phase flow dynamic simulation logging experiments in horizontal oil–water two-phase fl ow simulation wells were conducted using the Multiple Array Production Suite,which comprises a capacitance array tool(CAT)and a spinner array tool(SAT),and then the response characteristics of SAT and CAT in diff erent fl ow rates and water cut production conditions were studied.According to the response characteristics of CAT in diff erent water holdup ranges,interpolation imaging along the wellbore section determines the water holdup distribution,and then,the oil–water two-phase velocity fi eld in the fl ow section was reconstructed on the basis of the fl ow section water holdup distribution and the logging value of SAT and combined with the rheological equation of viscous fl uid,and the calculation method of the oil–water partial phase fl ow rate in the fl ow section was proposed.This new approach was applied in the experiment data calculations,and the results are basically consistent with the experimental data.The total fl ow rate and water holdup from the calculation are in agreement with the set values in the experiment,suggesting that the method has high accuracy.展开更多
Inner Mongolia is abundant in geothermal resources,but the development and utilization of medium-depth geothermal resources for clean heating in winter is still in the preliminary stage compared with the neighboring p...Inner Mongolia is abundant in geothermal resources,but the development and utilization of medium-depth geothermal resources for clean heating in winter is still in the preliminary stage compared with the neighboring provinces.In this paper,a recently developed geothermal heating system using the Mesozoic sandstone reservoirs in Baokang of Kailu Basin,Eastern Inner Mongolia was investigated,a threedimensional geological model of a pair of production and injection well was established,and numerical simulations on the long term operation performance were conducted and verified by pumping test and water level recovery test data.The effects of flow rates,the direction of wells,injection temperature and ratios on the flow field and water level in the thermal reservoir were analyzed.The results show that considering a 30-year operation period and a production rate from 90 m^(3)/h to 110 m^(3)/h,the optimum well spacing can be increased from 225 m to 245 m,with an average value of 235 m.With the decrease of the injection temperature,the cold front of the injection water has an increasing influence on the temperature in the production well.A complete injection or the principle of production according to injection is recommended in order to maintain the long-term operation stability.In addition,the location of the injection well should be arranged in the downstream of the natural flow field.The present results can provide a useful guide for the optimum design and performance prediction of geothermal wells,thus maintaining the production and injection balance and promoting the sustainable development and utilization of medium-depth and deep geothermal resources.展开更多
A simulation tool named BITSIM orienting production engineering is developed in order to improve enterprise＇s productivity and making up the scarcity of computer application. The architecture of BITSIM is presented f...A simulation tool named BITSIM orienting production engineering is developed in order to improve enterprise＇s productivity and making up the scarcity of computer application. The architecture of BITSIM is presented first. Hierarchical technique, control strategy based on multi-agent and simulation output analysis are depicted in detail then. In the end, an application example is taken out to prove that this system could be used to analyzing different hypothetical situation and configuring the auxiliary manufacturing system before production.展开更多
The fluid’s viscosity significantly affects the performance of a centrifugal pump.The entropy production method and leakage are employed to analyze the performance changes under various viscosities by numerical simul...The fluid’s viscosity significantly affects the performance of a centrifugal pump.The entropy production method and leakage are employed to analyze the performance changes under various viscosities by numerical simulation and validated by experiments.The results showed that increasing viscosity reduces both the pump head and efficiency.In addition,the optimal operating point shifts to the left.Leakage is influenced by vortex distribution in the front chamber and boundary layer thickness in wear-ring clearance,leading to an initial increase and subsequent decrease in leakage with increasing viscosity.The total entropy production Spro,Total inside the pump rises with increasing viscosity.The different mechanisms dominate under varying conditions:Turbulent dissipation dominates at low viscosity.Under high-viscosity conditions,energy loss is primarily caused by direct dissipation Spro,D and wall entropy production Spro,W.This study provides a deeper and more objective understanding of the energy characteristics of centrifugal pumps handling fluids of various viscosity,potentially aiding in optimizing pump design and improving energy conversion efficiency.展开更多
In the exploitation process of offshore natural gas hydrate(“hydrate”for short),it is necessary to take into consideration the wear of wellbore equipment caused by micron-sized sand particles after their breaking th...In the exploitation process of offshore natural gas hydrate(“hydrate”for short),it is necessary to take into consideration the wear of wellbore equipment caused by micron-sized sand particles after their breaking through the sand control facility of the wellbore.At present,however,there is no literature on the migration,deposition and blockage of micron-sized sand particles(<44 μm)after their flowing into the wellbore with the formation fluid.To deal with this situation,this paper took the sand particles in a throttling helical tube section for water transport in the process of depressurization hydrate exploitation as the research object.After a geometric model of flow channel was established for numerical simulation,the migration and deposition laws of micron-sized sand particles were analyzed and the critical non-deposition water velocity of micronsized sand particles under different conditions was obtained.And the following research results were obtained.First,micron-sized sand particles are mainly accumulated in the helical tube section of a complex pipeline,and the deposition of sand particles decreases with the increase of water velocity.The sand particles deposited in the upper part of the helical tube section are more difficult to clean than those in the lower part.Second,the critical non-deposition water velocity increases gradually with the increase of sand particle size and sand production concentration.Third,the variables are nondimensionalized by applying the Buckingham-P theorem.And the model for predicting the sand deposition concentration in the local complex wellbore section during hydrate production test can be obtained using the OriginPro 2019 non-linear fitting tool.Fourth,based on the proposed concept of sand deposition concentration ratio,combined with the deposition prediction model,it is convenient to calculate critical non-deposition water velocity of micron-sized sand particles and to judge the situation of sand deposition in the wellbore.In conclusion,a method for determining the critical non-deposition water velocity of micron-sized sand particles in the local complex wellbore section during the hydrate production test is proposed.And by virtue of this method,the critical non-deposition water velocity of micron-sized sand particles under three particle sizes and three sand production concentrations is obtained respectively.And the research results provide a basis for the reasonable arrangement of hydrate production system and pressure reduction range.展开更多
Automotive manufacturing is complex and includes the coordination of design in the manufacturing system. The manufacturing approaches over the past few years, disassembly have been a key issue, and it seems that simul...Automotive manufacturing is complex and includes the coordination of design in the manufacturing system. The manufacturing approaches over the past few years, disassembly have been a key issue, and it seems that simulation models are usually tailored to address a narrow set of industrial issues. This paper describes the development of the production line in the automobile manufacturing system through design, operation, and maintenance, based on multi-objectives of Algorithm and Simulation Model called MOA-SM. The both models are being developed at three different levels： the production line in the body and assembly shop, supply chain, and the production plan. The optimization tries to involve more objectives to solve the issues in manufacturing system. A solution that may optimize one performance measure may deteriorate since other performance solutions are difficult. The resulting algorithms are comparable to the simulation and multi-object in terms of success rate, assembly times, peak forces, moments, and have assembly times superior to those of a benchmark blind search algorithm.展开更多
With the continuous promotion of computer technology, the application system of virtual simulation technology has been further optimized and improved, and has been widely used in various fields of social development, ...With the continuous promotion of computer technology, the application system of virtual simulation technology has been further optimized and improved, and has been widely used in various fields of social development, such as urban construction, interior design, industrial simulation and tourism teaching. China's three-dimensional animation production started relatively late, but has achieved good results with the support of related advanced technology in the process of development. Computer virtual simulation technology is an important technical support in the production of three-dimensional animation. In this paper, firstly, the related content of computer virtual simulation technology was introduced. Then, the specific application of this technology in the production of three-dimensional animation was further elaborated, so as to provide some reference for the improvement of the production effect of three-dimensional animation in the future.展开更多
NC machining of parts and components is developing in the direction of automation and intelligence.In addition,the automatic production line puts forward higher requirements for the overall layout,technological proces...NC machining of parts and components is developing in the direction of automation and intelligence.In addition,the automatic production line puts forward higher requirements for the overall layout,technological process and production tempo.The layout and simulation of the production line can more directly reflect the problems that may occur in the operation of the production line,and solve these problems through scientific methods.This project uses VisualOne software to simulate the operation of the intelligent manufacturing production line,which can directly find the existing problems in the layout of the production line and the process of the craftsmen,and optimize the layout of the production line.In addition,it can provide reliable support for the equipment procurement and on-site construction of the intelligent manufacturing automation production line in the later stage.展开更多
SARP Workshop on risk analysis of agroecological zonation and optimization of crop rotation was held at CNRRI’s research center on 24—27 Oct, 1995. Experts from Philippines, India, China, and IRRI were present in th...SARP Workshop on risk analysis of agroecological zonation and optimization of crop rotation was held at CNRRI’s research center on 24—27 Oct, 1995. Experts from Philippines, India, China, and IRRI were present in the workshop. Participants exchanged the research results on the field of land use, soil erosion. optimization of rice—wheat, rice—peanut, rice—corn cropping system in the different environments, risk analysis of rice based cropping system, nitrogen balance in rice based cropping system with system approach, demonstrated models used in their studies, and discussed the ongoing cooperative research.展开更多
In order to produce natural gas hydrate safely and efficiently,it is quite crucial to research the stability of hydrate reservoir in the process of its exploitation.The coupled thermal-hydrodynamic-mechanical(THM)nume...In order to produce natural gas hydrate safely and efficiently,it is quite crucial to research the stability of hydrate reservoir in the process of its exploitation.The coupled thermal-hydrodynamic-mechanical(THM)numerical simulation can clearly present the mechanical response laws in the process of hydrate exploitation by horizontal well,but the model is often simplified as a profile vertical to the production well,so the evolution characteristics of real formation deformation space cannot be described sufficiently.To this end,this paper develops a coupled THM simulator applicable to the large-scale hydrate exploitation by horizontal well by introducing interactive interface to the FLAC mechanics program based on the hydrate exploitation program TOUGHþHYDRATE.Then,based on the field data of second hydrate production test in South China Sea,the gas and water production and formation deformation laws under the middle-and long-term development conditions of horizontal wells are studied by taking the actual gas production of horizontal well during the production test as the constraint of coupled THM model.And the following research results are obtained.First,when the production pressure is 7 MPa and the horizontal well length is 300 m,the gas production of horizontal well can reach 1190×10^(4)m^(3),the pressure drop has a larger influence range in the free gas layer,the produced gas mainly comes from the free gas layer and the hydrate layer and the hydrate dissociation range is not large.Second,it is predicted that the seafloor settlement is about 0.16 m after 60 days'production test and 0.52 m after osne year's production.In conclusion,hydrate exploitation by horizontal well can cause a large range of seafloor settlement.The seafloor surface settles linearly and continuously and the spatial settlement distribute is in the shape of ellipse.What's more,the greatest deformation(vertical displacement)occurs at the horizontal well and above it,where formation damage happens the easiest.It is recommended to study seafloor deformation and landslip risk under the conditions of middle and long-term production based on seafloor topography,valley distribution and nonuniform spatial thickness of mineral ores.展开更多
基金The National Basic Research Program of China(973Program)(No.2010CB732206)the National Natural Science Foundation of China(No.21076044,21276050)
文摘Biodiesel industrial production based on a solid base catalyst in a fixed-bed was simulated. The lab and bench scale experiments were carded out effectively, in which the kinetic model is established and it can describe the transesterification reaction well. The Antoine equation of biodiesel is regressed with the vapor-liquid data cited of literature. The non-random two liquid （NRTL） model is applied to describe the system of fatty acid methyl ester （FAME）, methanol and glycerol and parameters are obtained. The Ternary phase map is obtained from Aspen Plus via the liquid-liquid equilibrium （LLE） data. In order to describe the production in a fixed-bed performs in industrial scale after being magnified 1 000 times, the Aspen Plus simulation is employed, where two flowsheets are simulated to predict material and energy consumption. The simulation results prove that at least 350. 42 kW energy consumption can be reduced per hour to produce per ton biodiesel compared with data reported in previous references.
基金supported by China National Program on Key Basic Research Project (973 Program) (Grant No. 2006CB705805)National Key Scientific and Technological Project (Grant No. 2008ZX05009-004)
文摘For extra-low permeability reservoirs, with a permeability of about 0.3×10?3 μm2, fluid flow and production performance in cores were studied. A long core holder with a multi-location piezometric measurement was specially designed. An artificial long core, about 700 mm long and with a cross section of 45mm×45mm, was used. In the experiment, pressure distribution along the core can be measured in real time. Single phase flow in the core was investigated. Different modes of production in long cores were also simulated including natural depletion, water flooding, and advanced water flooding. Through physical simulation, flow parameters were collected and production characteristics in extra-low permeability cores were studied. From experimental results, it can be seen that fluid flow in extra-low permeability cores is different from that in high permeability cores. Transmission of pressure in extra-low permeability cores is very slow, and it needs a long time for the pressure to become stable. The distribution curve of pressure along the core is nonlinear and the production rate in extra-low permeability reservoirs decreases sharply. The development effects of different production modes in extra-low permeability cores were compared with one another. Among the production modes, advanced water flooding has much potential for effective development of extra-low permeability reservoirs. Natural depletion and conventional water flooding can also be used in early production periods. In addition, the countermeasures and some ideas especially for the potential development of extra-low permeability reservoirs are suggested.
基金Item Sponsored by Scientific Research Program Foundation of Shanghai City of China(04DZ05621)
文摘Based on the casting manufacture practice of steel slabs by CSP technology, the flow and the temperature fields of the funnel mould and the secondary cooling segment were simulated using the commercial code, CFX4. Compared with other physical investigations, the correlative data of the present simulation results are in good agreement with them. Therefore, a more comprehensive survey for metallurgy characteristic of the flow and the temperature fields in CSP continuous casting process can be achieved.
基金supported by the National Key R&D Program of China(No.2018YFA0800900).
文摘The bioactive constituents found in natural products(NPs)are crucial in protein-ligand interactions and drug discovery.However,it is difficult to identify ligand molecules from complex NPs that specifically bind to target protein,which often requires time-consuming and labor-intensive processes such as isolation and enrichment.To address this issue,in this study we developed a method that combines ultra-high performance liquid chromatography-electrospray ionization-mass spectrometry(UHPLCESI-MS)with molecular dynamics(MD)simulation to identify and observe,rapidly and efficiently,the bioactive components in NPs that bind to specific protein target.In this method,a specific protein target was introduced online using a three-way valve to form a protein-ligand complex.The complex was then detected in real time using high-resolution MS to identify potential ligands.Based on our method,only 10 molecules from green tea(a representative natural product),including the commonly reported epigallocatechin gallate(EGCG)and epicatechin gallate(ECG),as well as the previously unreported eepicatechin(4β→8)-epigallocatechin 3-O-gallate(EC-EGCG)and eepiafzelechin 3-O-gallate-(4β→8)-epigallocatechin 3-O-gallate(EFG-EGCG),were screened out,which could form complexes with Aβ_(1-42)(a representative protein target),and could be potential ligands of Aβ_(1-42).Among of them,EC-EGCG demonstrated the highest binding free energy with Aβ_(1-42)(−68.54±3.82 kcal/mol).On the other side,even though the caffeine had the highest signal among green tea extracts,it was not observed to form a complex with Aβ_(1-42).Compared to other methods such as affinity selection mass spectrometry(ASMS)and native MS,our method is easy to operate and interpret the data.Undoubtedly,it provides a new methodology for potential drug discovery in NPs,and will accelerate the research on screening ligands for specific proteins from complex NPs.
文摘Gas production from multiple coal seams has become common practice in many coal basins around the world. Although gas production rates are typically enhanced, the economic viability of such practice is not well studied. In order to investigate the technical and economic feasibility of multiple coal seams production, reservoir simulation integrated with economics modelling was performed to study the effect of important reservoir properties of the secondary coal seam on production and economic performance using both vertical and horizontal wells. The results demonstrated that multiple seam gas production of using both vertical and horizontal wells have competitive advantage over single layer production under most scenarios. Gas content and permeability of the secondary coal seam are the most important reservoir properties that have impact on the economic feasibility of multiple seam gas production. The comparison of vertical well and horizontal well performance showed that horizontal well is more economically attractive for both single well and gas field. Moreover, wellhead price is the most sensitive to the economic performance, followed by operating costs and government subsidy. Although the results of reservoir simulation combined with economic analysis are subject to assumptions, multiple seam gas production is more likely to maintain profitability compared with single layer production.
基金Shanghai Municipal Science & Technology Projects, China (No. 09DZ1203300, No. 10JC1415200)
文摘The production and energy coupling system is used to mainly present energy flow, material flow, information flow, and their coupling interaction. Through the modeling and simulation of this system, the performance of energy flow can be analyzed and optimized in the process industry. In order to study this system, the component based hybrid Petri net methodology (CpnHPN) is proposed, synthesizing a number of extended Petri net methods and using the concept of energy place, material place, and information place. Through the interface place in CpnHPN, the component based encapsulation is established, which enables the production and energy coupling system to be built, analyzed, and optimized on the multi-level framework. Considering the block and brief simulation for hybrid system, the CpnHPN model is simulated with Simulink/Stateflow. To illustrate the use of the proposed methodology, the application of CpnHPN in the energy optimization of chlorine balance system is provided.
文摘It is practical, economic and sometimes essential to derive rules or conclusions by performing lesser runs of experiments. In this part, a methodology based on 2 f factorial design was brought up to derive guidelines to simulate growth curve and production of sugars by Spirulina (Arthrospira) maxima . The growth curve or accumulation process of sugars was idealized by sets of straight lines limited by phase transfers of growth or accumulation of sugars. Normal analyses of the critical values of the transfers were used to derive their linear relationships with the initial conditions of the experimental factors. These linear functions were called guidelines and were used to simulate the growth curve or accumulation of sugars. Generalization of the guideline technique was determined by the kinetic limitation of nutrient nitrogen or sulfur that was dependent upon their stoichiometric deficiency directly derived from their initial values in the medium. This method uses the initial conditions of culture and does not need measurements of concentrations of nitrate, sulfate and pigments during cultivation. It is a practical and useful alternative way to trace and predict approximately the growth curve and production of sugars by S. maxima .
基金supported by the National Natural Science Foundation of China(69673044).
文摘The article established the HDRICE model by modifying the structure of the ORYZA1 model and revising its parameters by field experiments. The HDRICE model consists of the modules of morphological development of rice, daily dry matter accumulation and partitioning, daily CO2 assimilation of the canopy, leaf area, and tiller development. The model preferably simulated the dynamic rice development because of the thorough integration of the effects of temperature and light on the rates of rice development, photosynthesis, respiration, and. other ecophysiological processes. In addition, this model has attainable grain yield in the test experiment that showed the potential yield of cultivar Xieyou 46 ranged from 11 to 13 tons ha-~. Besides, the model was used to optimize the combinations of the transplanting date, seedling age and density for cultivar Xieyou 46 at Jinhua area, and the population quantitative indices to attain the potential yield such as maximum stems, effective panicles, filled grain number/leaf area, and so on. The result showed that the combination of transplanting date on July 25, seedling age of 35 days and base seedling density of 1.33 x 106ha-1 is the optimum combination for the second hybrid rice production in Jinhua County, China. And the maximum stems, the effective panicles, the filled grain per panicle, the peak of optimum LAI, LAI in later filling stage, and the filled grain number/leaf were 6.03×10^6ha, 3.99×10^6ha, 119.2, 8.59, 5-6, and 0.64, respectively.
文摘Due to the variable output of renewable energy (RE) generation, difficulties of dispatching RE for power system operators could not be avoided. One of possible solutions is the energy storage technology, especially the battery storage system. The large-scale energy storage system is available to support power system reliable flexibility for load following and system frequency regulation. In this paper, the bottlenecks of large-scale solar power generation dispatching and operation in Qinghai grid are discussed, and a new PV-energy storage coordinated dispatching method is proposed for reduction of PV curtailment in Qinghai. Moreover, the validation based on the time-series production simulation is provided using real data from Qinghai. The results indicate that the proposed method can effectively decrease the curtailment of solar power and future vision of large-scale solar power coordinated operation with energy storage system is also presented.
基金Supported by the National Natural Science Foundation of China(52192622,52304003).
文摘Based on the independently developed true triaxial multi-physical field large-scale physical simulation system of in-situ injection and production,we conducted physical simulation of long-term multi-well injection and production in the hot dry rocks of the Gonghe Basin,Qinghai Province,NW China.Through multi-well connectivity experiments,the spatial distribution characteristics of the natural fracture system in the rock samples and the connectivity between fracture and wellbore were clarified.The injection and production wells were selected to conduct the experiments,namely one injection well and two production wells,one injection well and one production well.The variation of several physical parameters in the production well was analyzed,such as flow rate,temperature,heat recovery rate and fluid recovery.The results show that under the combination of thermal shock and injection pressure,the fracture conductivity was enhanced,and the production temperature showed a downward trend.The larger the flow rate,the faster the decrease.When the local closed area of the fracture was gradually activated,new heat transfer areas were generated,resulting in a lower rate of increase or decrease in the mining temperature.The heat recovery rate was mainly controlled by the extraction flow rate and the temperature difference between injection and production fluid.As the conductivity of the leak-off channel increased,the fluid recovery of the production well rapidly decreased.The influence mechanisms of dominant channels and fluid leak-off on thermal recovery performance are different.The former limits the heat exchange area,while the latter affects the flow rate of the produced fluid.Both of them are important factors affecting the long-term and efficient development of hot dry rock.
基金supported by National Natural Science Foundation of China(41474115,42174155)Open Fund of Key Laboratory of Exploration Technologies for Oil and Gas Resources(Yangtze University)Ministry of Education of China(No K2018-02)。
文摘The distributions of local velocity and local phase holdup along the radial direction of pipes are complicated because of gravity differentiation,and the distribution of fluid velocity fi eld changes along the gravity direction in horizontal wells.Therefore,measuring the mixture flow and water holdup is difficult,resulting in poor interpretation accuracy of the production logging output profile.In this paper,oil–water two-phase flow dynamic simulation logging experiments in horizontal oil–water two-phase fl ow simulation wells were conducted using the Multiple Array Production Suite,which comprises a capacitance array tool(CAT)and a spinner array tool(SAT),and then the response characteristics of SAT and CAT in diff erent fl ow rates and water cut production conditions were studied.According to the response characteristics of CAT in diff erent water holdup ranges,interpolation imaging along the wellbore section determines the water holdup distribution,and then,the oil–water two-phase velocity fi eld in the fl ow section was reconstructed on the basis of the fl ow section water holdup distribution and the logging value of SAT and combined with the rheological equation of viscous fl uid,and the calculation method of the oil–water partial phase fl ow rate in the fl ow section was proposed.This new approach was applied in the experiment data calculations,and the results are basically consistent with the experimental data.The total fl ow rate and water holdup from the calculation are in agreement with the set values in the experiment,suggesting that the method has high accuracy.
基金supported by China Geological Survey Program(DD20190128)Natural Science Foundation of Hebei Province(No.E2022202082)。
文摘Inner Mongolia is abundant in geothermal resources,but the development and utilization of medium-depth geothermal resources for clean heating in winter is still in the preliminary stage compared with the neighboring provinces.In this paper,a recently developed geothermal heating system using the Mesozoic sandstone reservoirs in Baokang of Kailu Basin,Eastern Inner Mongolia was investigated,a threedimensional geological model of a pair of production and injection well was established,and numerical simulations on the long term operation performance were conducted and verified by pumping test and water level recovery test data.The effects of flow rates,the direction of wells,injection temperature and ratios on the flow field and water level in the thermal reservoir were analyzed.The results show that considering a 30-year operation period and a production rate from 90 m^(3)/h to 110 m^(3)/h,the optimum well spacing can be increased from 225 m to 245 m,with an average value of 235 m.With the decrease of the injection temperature,the cold front of the injection water has an increasing influence on the temperature in the production well.A complete injection or the principle of production according to injection is recommended in order to maintain the long-term operation stability.In addition,the location of the injection well should be arranged in the downstream of the natural flow field.The present results can provide a useful guide for the optimum design and performance prediction of geothermal wells,thus maintaining the production and injection balance and promoting the sustainable development and utilization of medium-depth and deep geothermal resources.
文摘A simulation tool named BITSIM orienting production engineering is developed in order to improve enterprise＇s productivity and making up the scarcity of computer application. The architecture of BITSIM is presented first. Hierarchical technique, control strategy based on multi-agent and simulation output analysis are depicted in detail then. In the end, an application example is taken out to prove that this system could be used to analyzing different hypothetical situation and configuring the auxiliary manufacturing system before production.
基金supported by the National Natural Science Foundation of China(Grant Nos.52079058 and 52209113)the Natural Science Foundation of Jiangsu Province(Grant Nos.BK20230011 and BK20220544)+1 种基金China Postdoctoral Science Foundation(Grant No.2023M731367)Postgraduate Research&Practice Innovation Program of Jiangsu Province(Grant No.KYCX23_3698).
文摘The fluid’s viscosity significantly affects the performance of a centrifugal pump.The entropy production method and leakage are employed to analyze the performance changes under various viscosities by numerical simulation and validated by experiments.The results showed that increasing viscosity reduces both the pump head and efficiency.In addition,the optimal operating point shifts to the left.Leakage is influenced by vortex distribution in the front chamber and boundary layer thickness in wear-ring clearance,leading to an initial increase and subsequent decrease in leakage with increasing viscosity.The total entropy production Spro,Total inside the pump rises with increasing viscosity.The different mechanisms dominate under varying conditions:Turbulent dissipation dominates at low viscosity.Under high-viscosity conditions,energy loss is primarily caused by direct dissipation Spro,D and wall entropy production Spro,W.This study provides a deeper and more objective understanding of the energy characteristics of centrifugal pumps handling fluids of various viscosity,potentially aiding in optimizing pump design and improving energy conversion efficiency.
基金supported by the National Major Science and Technology Project“Drilling hydraulics and borehole cleaning supporting techniques for complex structural cluster wells”(No.:2017ZX05009-003)National Natural Science Foundation Project of China“Rotary drive mechanism study on the hydraulicmagnetic coupling self-rotation borehole cleaning tools”(No.:51674087)Innovative Science and Research Project for the Postgraduates of Northeast Petroleum University“Cohesion mechanism and flow assurance study on the natural gas hydrates during deep-water drilling”(No.:YJSCX2017-008NEPU).
文摘In the exploitation process of offshore natural gas hydrate(“hydrate”for short),it is necessary to take into consideration the wear of wellbore equipment caused by micron-sized sand particles after their breaking through the sand control facility of the wellbore.At present,however,there is no literature on the migration,deposition and blockage of micron-sized sand particles(<44 μm)after their flowing into the wellbore with the formation fluid.To deal with this situation,this paper took the sand particles in a throttling helical tube section for water transport in the process of depressurization hydrate exploitation as the research object.After a geometric model of flow channel was established for numerical simulation,the migration and deposition laws of micron-sized sand particles were analyzed and the critical non-deposition water velocity of micronsized sand particles under different conditions was obtained.And the following research results were obtained.First,micron-sized sand particles are mainly accumulated in the helical tube section of a complex pipeline,and the deposition of sand particles decreases with the increase of water velocity.The sand particles deposited in the upper part of the helical tube section are more difficult to clean than those in the lower part.Second,the critical non-deposition water velocity increases gradually with the increase of sand particle size and sand production concentration.Third,the variables are nondimensionalized by applying the Buckingham-P theorem.And the model for predicting the sand deposition concentration in the local complex wellbore section during hydrate production test can be obtained using the OriginPro 2019 non-linear fitting tool.Fourth,based on the proposed concept of sand deposition concentration ratio,combined with the deposition prediction model,it is convenient to calculate critical non-deposition water velocity of micron-sized sand particles and to judge the situation of sand deposition in the wellbore.In conclusion,a method for determining the critical non-deposition water velocity of micron-sized sand particles in the local complex wellbore section during the hydrate production test is proposed.And by virtue of this method,the critical non-deposition water velocity of micron-sized sand particles under three particle sizes and three sand production concentrations is obtained respectively.And the research results provide a basis for the reasonable arrangement of hydrate production system and pressure reduction range.
文摘Automotive manufacturing is complex and includes the coordination of design in the manufacturing system. The manufacturing approaches over the past few years, disassembly have been a key issue, and it seems that simulation models are usually tailored to address a narrow set of industrial issues. This paper describes the development of the production line in the automobile manufacturing system through design, operation, and maintenance, based on multi-objectives of Algorithm and Simulation Model called MOA-SM. The both models are being developed at three different levels： the production line in the body and assembly shop, supply chain, and the production plan. The optimization tries to involve more objectives to solve the issues in manufacturing system. A solution that may optimize one performance measure may deteriorate since other performance solutions are difficult. The resulting algorithms are comparable to the simulation and multi-object in terms of success rate, assembly times, peak forces, moments, and have assembly times superior to those of a benchmark blind search algorithm.
文摘With the continuous promotion of computer technology, the application system of virtual simulation technology has been further optimized and improved, and has been widely used in various fields of social development, such as urban construction, interior design, industrial simulation and tourism teaching. China's three-dimensional animation production started relatively late, but has achieved good results with the support of related advanced technology in the process of development. Computer virtual simulation technology is an important technical support in the production of three-dimensional animation. In this paper, firstly, the related content of computer virtual simulation technology was introduced. Then, the specific application of this technology in the production of three-dimensional animation was further elaborated, so as to provide some reference for the improvement of the production effect of three-dimensional animation in the future.
基金supported by 2019 Project of the 13th Five-year Plan of Fujian Education and Science(FJJKCGZ19-016)。
文摘NC machining of parts and components is developing in the direction of automation and intelligence.In addition,the automatic production line puts forward higher requirements for the overall layout,technological process and production tempo.The layout and simulation of the production line can more directly reflect the problems that may occur in the operation of the production line,and solve these problems through scientific methods.This project uses VisualOne software to simulate the operation of the intelligent manufacturing production line,which can directly find the existing problems in the layout of the production line and the process of the craftsmen,and optimize the layout of the production line.In addition,it can provide reliable support for the equipment procurement and on-site construction of the intelligent manufacturing automation production line in the later stage.
文摘SARP Workshop on risk analysis of agroecological zonation and optimization of crop rotation was held at CNRRI’s research center on 24—27 Oct, 1995. Experts from Philippines, India, China, and IRRI were present in the workshop. Participants exchanged the research results on the field of land use, soil erosion. optimization of rice—wheat, rice—peanut, rice—corn cropping system in the different environments, risk analysis of rice based cropping system, nitrogen balance in rice based cropping system with system approach, demonstrated models used in their studies, and discussed the ongoing cooperative research.
基金Basic Foresight Research Project of Oil and GasDevelopment from Sinopec Ministry of Science and Technology:“Key technologies of drilling and completion and development of coring equipment for natural gas hydrate”(No.P20040-3)Sinopec Shengli Oilfield Post-doctoral Research Project:“Sand Production Dynamic Prediction and Technical Policy Boundaries in Natural Gas Hydrate Reservoir”(No.YKB2107)Youth Science Fund Project of National Natural Science Foundation of China:“Study on Non-Darcy Flow Characteristics of and Its Impact on Productivity in Low PermeabilityMuddy Silt Hydrate Reservoirs in South China Sea”(No.42102302).
文摘In order to produce natural gas hydrate safely and efficiently,it is quite crucial to research the stability of hydrate reservoir in the process of its exploitation.The coupled thermal-hydrodynamic-mechanical(THM)numerical simulation can clearly present the mechanical response laws in the process of hydrate exploitation by horizontal well,but the model is often simplified as a profile vertical to the production well,so the evolution characteristics of real formation deformation space cannot be described sufficiently.To this end,this paper develops a coupled THM simulator applicable to the large-scale hydrate exploitation by horizontal well by introducing interactive interface to the FLAC mechanics program based on the hydrate exploitation program TOUGHþHYDRATE.Then,based on the field data of second hydrate production test in South China Sea,the gas and water production and formation deformation laws under the middle-and long-term development conditions of horizontal wells are studied by taking the actual gas production of horizontal well during the production test as the constraint of coupled THM model.And the following research results are obtained.First,when the production pressure is 7 MPa and the horizontal well length is 300 m,the gas production of horizontal well can reach 1190×10^(4)m^(3),the pressure drop has a larger influence range in the free gas layer,the produced gas mainly comes from the free gas layer and the hydrate layer and the hydrate dissociation range is not large.Second,it is predicted that the seafloor settlement is about 0.16 m after 60 days'production test and 0.52 m after osne year's production.In conclusion,hydrate exploitation by horizontal well can cause a large range of seafloor settlement.The seafloor surface settles linearly and continuously and the spatial settlement distribute is in the shape of ellipse.What's more,the greatest deformation(vertical displacement)occurs at the horizontal well and above it,where formation damage happens the easiest.It is recommended to study seafloor deformation and landslip risk under the conditions of middle and long-term production based on seafloor topography,valley distribution and nonuniform spatial thickness of mineral ores.
