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Non-negative least squares variance component estimation of mixed additive and multiplicative random error model
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作者 Hao Xiao Leyang Wang 《Geodesy and Geodynamics》 2025年第5期617-623,共7页
In the variance component estimation(VCE)of geodetic data,the problem of negative VCE is likely to occur.In the ordinary additive error model,there have been related studies to solve the problem of negative variance c... In the variance component estimation(VCE)of geodetic data,the problem of negative VCE is likely to occur.In the ordinary additive error model,there have been related studies to solve the problem of negative variance components.However,there is still no related research in the mixed additive and multiplicative random error model(MAMREM).Based on the MAMREM,this paper applies the nonnegative least squares variance component estimation(NNLS-VCE)algorithm to this model.The correlation formula and iterative algorithm of NNLS-VCE for MAMREM are derived.The problem of negative variance in VCE for MAMREM is solved.This paper uses the digital simulation example and the Digital Terrain Mode(DTM)to prove the proposed algorithm's validity.The experimental results demonstrated that the proposed algorithm can effectively correct the VCE in MAMREM when there is a negative VCE. 展开更多
关键词 Mixed additive and multiplicative random error model Stochastic model non-negative least squares variance component estimation
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Predicting CircRNA-Disease Associations via Non-Negative Matrix Factorization Fused with Multiple Similarity Networks
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作者 LU Pengli LI Shiying 《Journal of Shanghai Jiaotong university(Science)》 2025年第4期709-719,共11页
CircRNAs,widely found throughout the human bodies,play a crucial role in regulating various biological processes and are closely linked to complex human diseases.Investigating potential associations between circRNAs a... CircRNAs,widely found throughout the human bodies,play a crucial role in regulating various biological processes and are closely linked to complex human diseases.Investigating potential associations between circRNAs and diseases can enhance our understanding of diseases and provide new strategies and tools for early diagnosis,treatment,and disease prevention.However,existing models have limitations in accurately capturing similarities,handling the sparse and noise attributes of association networks,and fully leveraging bioinformatical aspects from multiple viewpoints.To address these issues,this study introduces a new non-negative matrix factorization-based framework called NMFMSN.First,we incorporate circRNA sequence data and disease semantic information to compute circRNA and disease similarity,respectively.Given the sparse known associations between circRNAs and diseases,we reconstruct the network to complete more associations by imputing missing links based on neighboring circRNA and disease interactions.Finally,we integrate these two similarity networks into a non-negative matrix factorization framework to identify potential circRNA-disease associations.Upon conducting 5-fold cross-validation and leave-one-out cross-validation,the AUC values for NMFMSN reach 0.9712 and 0.9768,respectively,outperforming the currently most advanced models.Case studies on lung cancer and hepatocellular carcinoma show that NMFMSN is a good way to predict new associations between circRNAs and diseases. 展开更多
关键词 circRNA-disease associations circRNA sequence data disease semantic information non-negative matrix factorization
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MAXIMAL FUNCTION CHARACTERIZATIONS OF HARDY SPACES ASSOCIATED WITH BOTH NON-NEGATIVE SELF-ADJOINT OPERATORS SATISFYING GAUSSIAN ESTIMATES AND BALL QUASI-BANACH FUNCTION SPACES
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作者 林孝盛 杨大春 +1 位作者 杨四辈 袁文 《Acta Mathematica Scientia》 SCIE CSCD 2024年第2期484-514,共31页
Assume that L is a non-negative self-adjoint operator on L^(2)(ℝ^(n))with its heat kernels satisfying the so-called Gaussian upper bound estimate and that X is a ball quasi-Banach function space onℝ^(n) satisfying som... Assume that L is a non-negative self-adjoint operator on L^(2)(ℝ^(n))with its heat kernels satisfying the so-called Gaussian upper bound estimate and that X is a ball quasi-Banach function space onℝ^(n) satisfying some mild assumptions.Let HX,L(ℝ^(n))be the Hardy space associated with both X and L,which is defined by the Lusin area function related to the semigroup generated by L.In this article,the authors establish various maximal function characterizations of the Hardy space HX,L(ℝ^(n))and then apply these characterizations to obtain the solvability of the related Cauchy problem.These results have a wide range of generality and,in particular,the specific spaces X to which these results can be applied include the weighted space,the variable space,the mixed-norm space,the Orlicz space,the Orlicz-slice space,and the Morrey space.Moreover,the obtained maximal function characterizations of the mixed-norm Hardy space,the Orlicz-slice Hardy space,and the Morrey-Hardy space associated with L are completely new. 展开更多
关键词 Hardy space ball quasi-Banach function space Gaussian upper bound estimate non-negative self-adjoint operator maximal function
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Sparseness-controlled non-negative tensor factorization and its application in machinery fault diagnosis 被引量:1
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作者 彭森 许飞云 +1 位作者 贾民平 胡建中 《Journal of Southeast University(English Edition)》 EI CAS 2009年第3期346-350,共5页
Aiming at the problems of bispectral analysis when applied to machinery fault diagnosis, a machinery fault feature extraction method based on sparseness-controlled non-negative tensor factorization (SNTF) is propose... Aiming at the problems of bispectral analysis when applied to machinery fault diagnosis, a machinery fault feature extraction method based on sparseness-controlled non-negative tensor factorization (SNTF) is proposed. First, a non-negative tensor factorization(NTF) algorithm is improved by imposing sparseness constraints on it. Secondly, the bispectral images of mechanical signals are obtained and stacked to form a third-order tensor. Thirdly, the improved algorithm is used to extract features, which are represented by a series of basis images from this tensor. Finally, coefficients indicating these basis images' weights in constituting original bispectral images are calculated for fault classification. Experiments on fault diagnosis of gearboxes show that the extracted features can not only reveal some nonlinear characteristics of the system, but also have intuitive meanings with regard to fault characteristic frequencies. These features provide great convenience for the interpretation of the relationships between machinery faults and corresponding bispectra. 展开更多
关键词 non-negative tensor factorization SPARSENESS feature extraction bispectrum gearbox
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Local hierarchical non-negative tensor factorization and its application in machinery fault diagnosis 被引量:1
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作者 王飞 许飞云 王海军 《Journal of Southeast University(English Edition)》 EI CAS 2011年第4期394-399,共6页
Aiming at the slow convergence and low accuracy problems of the traditional non-negative tensor factorization, a local hierarchical non-negative tensor factorization method is proposed by applying the local objective ... Aiming at the slow convergence and low accuracy problems of the traditional non-negative tensor factorization, a local hierarchical non-negative tensor factorization method is proposed by applying the local objective function theory to non- negative tensor factorization and combining the three semi-non- negative matrix factorization(NMF) model. The effectiveness of the method is verified by the facial feature extraction experiment. Through the decomposition of a series of an air compressor's vibration signals composed in the form of a bispectrum by this new method, the basis images representing the fault features and corresponding weight matrices are obtained. Then the relationships between characteristics and faults are analyzed and the fault types are classified by importing the weight matrices into the BP neural network. Experimental results show that the accuracy of fault diagnosis is improved by this new method compared with other feature extraction methods. 展开更多
关键词 non-negative tensor factorization BISPECTRUM feature extraction air compressor BP neural network
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Feature Extraction and Recognition for Rolling Element Bearing Fault Utilizing Short-Time Fourier Transform and Non-negative Matrix Factorization 被引量:29
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作者 GAO Huizhong LIANG Lin +1 位作者 CHEN Xiaoguang XU Guanghua 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2015年第1期96-105,共10页
Due to the non-stationary characteristics of vibration signals acquired from rolling element bearing fault, thc time-frequency analysis is often applied to describe the local information of these unstable signals smar... Due to the non-stationary characteristics of vibration signals acquired from rolling element bearing fault, thc time-frequency analysis is often applied to describe the local information of these unstable signals smartly. However, it is difficult to classitythe high dimensional feature matrix directly because of too large dimensions for many classifiers. This paper combines the concepts of time-frequency distribution(TFD) with non-negative matrix factorization(NMF), and proposes a novel TFD matrix factorization method to enhance representation and identification of bearing fault. Throughout this method, the TFD of a vibration signal is firstly accomplished to describe the localized faults with short-time Fourier transform(STFT). Then, the supervised NMF mapping is adopted to extract the fault features from TFD. Meanwhile, the fault samples can be clustered and recognized automatically by using the clustering property of NMF. The proposed method takes advantages of the NMF in the parts-based representation and the adaptive clustering. The localized fault features of interest can be extracted as well. To evaluate the performance of the proposed method, the 9 kinds of the bearing fault on a test bench is performed. The proposed method can effectively identify the fault severity and different fault types. Moreover, in comparison with the artificial neural network(ANN), NMF yields 99.3% mean accuracy which is much superior to ANN. This research presents a simple and practical resolution for the fault diagnosis problem of rolling element bearing in high dimensional feature space. 展开更多
关键词 time-frequency distribution non-negative matrix factorization rolling element bearing feature extraction
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Graph Regularized L_p Smooth Non-negative Matrix Factorization for Data Representation 被引量:10
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作者 Chengcai Leng Hai Zhang +2 位作者 Guorong Cai Irene Cheng Anup Basu 《IEEE/CAA Journal of Automatica Sinica》 EI CSCD 2019年第2期584-595,共12页
This paper proposes a Graph regularized Lpsmooth non-negative matrix factorization(GSNMF) method by incorporating graph regularization and L_p smoothing constraint, which considers the intrinsic geometric information ... This paper proposes a Graph regularized Lpsmooth non-negative matrix factorization(GSNMF) method by incorporating graph regularization and L_p smoothing constraint, which considers the intrinsic geometric information of a data set and produces smooth and stable solutions. The main contributions are as follows: first, graph regularization is added into NMF to discover the hidden semantics and simultaneously respect the intrinsic geometric structure information of a data set. Second,the Lpsmoothing constraint is incorporated into NMF to combine the merits of isotropic(L_2-norm) and anisotropic(L_1-norm)diffusion smoothing, and produces a smooth and more accurate solution to the optimization problem. Finally, the update rules and proof of convergence of GSNMF are given. Experiments on several data sets show that the proposed method outperforms related state-of-the-art methods. 展开更多
关键词 Data clustering dimensionality reduction GRAPH REGULARIZATION LP SMOOTH non-negative matrix factorization(SNMF)
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Total Variation Constrained Non-Negative Matrix Factorization for Medical Image Registration 被引量:4
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作者 Chengcai Leng Hai Zhang +2 位作者 Guorong Cai Zhen Chen Anup Basu 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2021年第5期1025-1037,共13页
This paper presents a novel medical image registration algorithm named total variation constrained graphregularization for non-negative matrix factorization(TV-GNMF).The method utilizes non-negative matrix factorizati... This paper presents a novel medical image registration algorithm named total variation constrained graphregularization for non-negative matrix factorization(TV-GNMF).The method utilizes non-negative matrix factorization by total variation constraint and graph regularization.The main contributions of our work are the following.First,total variation is incorporated into NMF to control the diffusion speed.The purpose is to denoise in smooth regions and preserve features or details of the data in edge regions by using a diffusion coefficient based on gradient information.Second,we add graph regularization into NMF to reveal intrinsic geometry and structure information of features to enhance the discrimination power.Third,the multiplicative update rules and proof of convergence of the TV-GNMF algorithm are given.Experiments conducted on datasets show that the proposed TV-GNMF method outperforms other state-of-the-art algorithms. 展开更多
关键词 Data clustering dimension reduction image registration non-negative matrix factorization(NMF) total variation(TV)
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PM_(2.5) source apportionment in a French urban coastal site under steelworks emission influences using constrained non-negative matrix factorization receptor model 被引量:3
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作者 Adib Kfoury Frederic Ledoux +3 位作者 Cloe Roche Gilles Delmaire Gilles Roussel Dominique Courcot 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2016年第2期114-128,共15页
The constrained weighted-non-negative matrix factorization(CW-NMF)hybrid receptor model was applied to study the influence of steelmaking activities on PM_(2.5)(particulate matter with equivalent aerodynamic diameter ... The constrained weighted-non-negative matrix factorization(CW-NMF)hybrid receptor model was applied to study the influence of steelmaking activities on PM_(2.5)(particulate matter with equivalent aerodynamic diameter less than 2.5μm)composition in Dunkerque,Northern France.Semi-diurnal PM_(2.5)samples were collected using a high volume sampler in winter 2010 and spring 2011 and were analyzed for trace metals,water-soluble ions,and total carbon using inductively coupled plasma–atomic emission spectrometry(ICP-AES),ICP-mass spectrometry(ICP-MS),ionic chromatography and micro elemental carbon analyzer.The elemental composition shows that NO_(3)^(-),SO_(4)^(2-),NH_4~+and total carbon are the main PM_(2.5)constituents.Trace metals data were interpreted using concentration roses and both influences of integrated steelworks and electric steel plant were evidenced.The distinction between the two sources is made possible by the use Zn/Fe and Zn/Mn diagnostic ratios.Moreover Rb/Cr,Pb/Cr and Cu/Cd combination ratio are proposed to distinguish the ISW-sintering stack from the ISW-fugitive emissions.The a priori knowledge on the influencing source was introduced in the CW-NMF to guide the calculation.Eleven source profiles with various contributions were identified:8 are characteristics of coastal urban background site profiles and 3 are related to the steelmaking activities.Between them,secondary nitrates,secondary sulfates and combustion profiles give the highest contributions and account for 93%of the PM_(2.5)concentration.The steelwork facilities contribute in about 2%of the total PM_(2.5)concentration and appear to be the main source of Cr,Cu,Fe,Mn,Zn. 展开更多
关键词 PM_(2.5) Receptor modeling non-negative matrix factorization Source apportionment Steelworks
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Isolation of Whole-plant Multiple Oscillations via Non-negative Spectral Decompositio 被引量:2
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作者 夏春明 郑建荣 John Howell 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2007年第3期353-360,共8页
Constrained spectral non-negative matrix factorization(NMF)analysis of perturbed oscillatory process control loop variable data is performed for the isolation of multiple plant-wide oscillatory sources.The technique i... Constrained spectral non-negative matrix factorization(NMF)analysis of perturbed oscillatory process control loop variable data is performed for the isolation of multiple plant-wide oscillatory sources.The technique is described and demonstrated by analyzing data from both simulated and real plant data of a chemical process plant. Results show that the proposed approach can map multiple oscillatory sources onto the most appropriate control loops,and has superior performance in terms of reconstruction accuracy and intuitive understanding compared with spectral independent component analysis(ICA). 展开更多
关键词 process monitoring multiple oscillations non-negative matrix factorization SPARSE spectral analysis fault isolation
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Obtaining Profiles Based on Localized Non-negative Matrix Factorization 被引量:2
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作者 JIANGJi-xiang XUBao-wen +1 位作者 LUJian-jiang ZhouXiao-yu 《Wuhan University Journal of Natural Sciences》 EI CAS 2004年第5期580-584,共5页
Nonnegative matrix factorization (NMF) is a method to get parts-based features of information and form the typical profiles. But the basis vectors NMF gets are not orthogonal so that parts-based features of informatio... Nonnegative matrix factorization (NMF) is a method to get parts-based features of information and form the typical profiles. But the basis vectors NMF gets are not orthogonal so that parts-based features of information are usually redundancy. In this paper, we propose two different approaches based on localized non-negative matrix factorization (LNMF) to obtain the typical user session profiles and typical semantic profiles of junk mails. The LNMF get basis vectors as orthogonal as possible so that it can get accurate profiles. The experiments show that the approach based on LNMF can obtain better profiles than the approach based on NMF. Key words localized non-negative matrix factorization - profile - log mining - mail filtering CLC number TP 391 Foundation item: Supported by the National Natural Science Foundation of China (60373066, 60303024), National Grand Fundamental Research 973 Program of China (2002CB312000), National Research Foundation for the Doctoral Program of Higher Education of China (20020286004).Biography: Jiang Ji-xiang (1980-), male, Master candidate, research direction: data mining, knowledge representation on the Web. 展开更多
关键词 localized non-negative matrix factorization PROFILE log mining mail filtering
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High Quality Audio Object Coding Framework Based on Non-Negative Matrix Factorization 被引量:1
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作者 Tingzhao Wu Ruimin Hu +2 位作者 Xiaochen Wang Shanfa Ke Jinshan Wang 《China Communications》 SCIE CSCD 2017年第9期32-41,共10页
Object-based audio coding is the main technique of audio scene coding. It can effectively reconstruct each object trajectory, besides provide sufficient flexibility for personalized audio scene reconstruction. So more... Object-based audio coding is the main technique of audio scene coding. It can effectively reconstruct each object trajectory, besides provide sufficient flexibility for personalized audio scene reconstruction. So more and more attentions have been paid to the object-based audio coding. However, existing object-based techniques have poor sound quality because of low parameter frequency domain resolution. In order to achieve high quality audio object coding, we propose a new coding framework with introducing the non-negative matrix factorization(NMF) method. We extract object parameters with high resolution to improve sound quality, and apply NMF method to parameter coding to reduce the high bitrate caused by high resolution. And the experimental results have shown that the proposed framework can improve the coding quality by 25%, so it can provide a better solution to encode audio scene in a more flexible and higher quality way. 展开更多
关键词 object-based AUDIO CODING non-negative matrix FACTORIZATION AUDIO scenecoding
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Application and Effect of Intelligent Disinfection Robot in Non-Negative Pressure Isolation Ward of Novel Coronavirus Pneumonia Designated Hospital 被引量:5
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作者 Yuanli Chen Juan Wang +2 位作者 Yingying Zhang Wenjuan Song Liang Peng 《Open Journal of Nursing》 2020年第11期1048-1055,共8页
The application of intelligent disinfection robot in designated non-negative pressure isolation ward during the outbreak in novel coronavirus pneumonia. The construction and competition, disinfection mode of intellige... The application of intelligent disinfection robot in designated non-negative pressure isolation ward during the outbreak in novel coronavirus pneumonia. The construction and competition, disinfection mode of intelligent disinfection robot, the setting of disinfection point built on area and number of isolation ward, can be introduced below. Frequency can realize remote control when staff uses a table to give instruction and set disinfection mode, and then the intelligent disinfection robot returns automatically to the charging pile to charge when the instruction is completed. It can also autonomously move to sterilize without human participation, which makes man-machine separation and accurate disinfection come true. The chance of contact infection and exposure is decreased when an intelligent disinfection robot is used to sterilize the environment and object surface in an isolation ward, which can also reduce occupational exposure, achieve occupational protection of medical workers and ensure there is no hospital infection. 展开更多
关键词 Intelligent Disinfection Robot Novel Coronavirus Pneumonia non-negative Pressure Isolation Ward
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Encoding of rat working memory by power of multi-channel local field potentials via sparse non-negative matrix factorization 被引量:1
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作者 Xu Liu Tiao-Tiao Liu +3 位作者 Wen-Wen Bai Hu Yi Shuang-Yan Li Xin Tian 《Neuroscience Bulletin》 SCIE CAS CSCD 2013年第3期279-286,共8页
Working memory plays an important role in human cognition. This study investigated how working memory was encoded by the power of multichannel local field potentials (LFPs) based on sparse non negative matrix factor... Working memory plays an important role in human cognition. This study investigated how working memory was encoded by the power of multichannel local field potentials (LFPs) based on sparse non negative matrix factorization (SNMF). SNMF was used to extract features from LFPs recorded from the prefrontal cortex of four SpragueDawley rats during a memory task in a Y maze, with 10 trials for each rat. Then the powerincreased LFP components were selected as working memoryrelated features and the other components were removed. After that, the inverse operation of SNMF was used to study the encoding of working memory in the time frequency domain. We demonstrated that theta and gamma power increased significantly during the working memory task. The results suggested that postsynaptic activity was simulated well by the sparse activity model. The theta and gamma bands were meaningful for encoding working memory. 展开更多
关键词 sparse non-negative matrix factorization multi-channel local field potentials working memory prefrontal cortex
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Non-Negative Adaptive Mechanism-Based Sliding Mode Control for Parallel Manipulators with Uncertainties 被引量:1
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作者 Van-Truong Nguyen 《Computers, Materials & Continua》 SCIE EI 2023年第2期2771-2787,共17页
In this paper,a non-negative adaptive mechanism based on an adaptive nonsingular fast terminal sliding mode control strategy is proposed to have finite time and high-speed trajectory tracking for parallel manipulators... In this paper,a non-negative adaptive mechanism based on an adaptive nonsingular fast terminal sliding mode control strategy is proposed to have finite time and high-speed trajectory tracking for parallel manipulators with the existence of unknown bounded complex uncertainties and external disturbances.The proposed approach is a hybrid scheme of the online non-negative adaptive mechanism,tracking differentiator,and nonsingular fast terminal sliding mode control(NFTSMC).Based on the online non-negative adaptive mechanism,the proposed control can remove the assumption that the uncertainties and disturbances must be bounded for the NFTSMC controllers.The proposed controller has several advantages such as simple structure,easy implementation,rapid response,chattering-free,high precision,robustness,singularity avoidance,and finite-time convergence.Since all control parameters are online updated via tracking differentiator and non-negative adaptive law,the tracking control performance at high-speed motions can be better in real-time requirement and disturbance rejection ability.Finally,simulation results validate the effectiveness of the proposed method. 展开更多
关键词 Parallel manipulator uncertainties and disturbances nonsingular fast terminal sliding mode control non-negative adaptive mechanism tracking differentiator
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A novel trilinear decomposition algorithm:Three-dimension non-negative matrix factorization
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作者 Hong Tao Gao Dong Mei Dai Tong Hua Li 《Chinese Chemical Letters》 SCIE CAS CSCD 2007年第4期495-498,共4页
Non-negative matrix factorization (NMF) is a technique for dimensionality reduction by placing non-negativity constraints on the matrix. Based on the PARAFAC model, NMF was extended for three-dimension data decompos... Non-negative matrix factorization (NMF) is a technique for dimensionality reduction by placing non-negativity constraints on the matrix. Based on the PARAFAC model, NMF was extended for three-dimension data decomposition. The three-dimension nonnegative matrix factorization (NMF3) algorithm, which was concise and easy to implement, was given in this paper. The NMF3 algorithm implementation was based on elements but not on vectors. It could decompose a data array directly without unfolding, which was not similar to that the traditional algorithms do, It has been applied to the simulated data array decomposition and obtained reasonable results. It showed that NMF3 could be introduced for curve resolution in chemometrics. 展开更多
关键词 Three-dimension non-negative matrix factorization NMF3 ALGORITHM Data decomposition CHEMOMETRICS
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Simultaneous Identification of Process Structure, Parameters and Time-delay Based on Non-negative Garrote
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作者 Jian-Guo Wang Qian-Ping Xiao +3 位作者 Tiao Shen Shi-Wei Ma Wen-Tao Rao Yong-Jie Zhang 《International Journal of Automation and computing》 EI CSCD 2020年第6期873-882,共10页
In practice,the model structure,parameters and time-delay of the actual process may vary simultaneously.However,the general identification methods of the 3 items are performed with separate procedures which is very in... In practice,the model structure,parameters and time-delay of the actual process may vary simultaneously.However,the general identification methods of the 3 items are performed with separate procedures which is very inconvenient in practical application.In view of the fact that variable selection procedure can ensure a compact model with robust input-output,relation and in order to explore the feasibility of variable selection algorithm for the simultaneous identification of process structure,parameters and time-delay,non-negative garrote(NNG)algorithm is introduced and applied to system identification and the corresponding procedures are presented.The application of NNG variable selection algorithm to the identification of single input single output(SISO)system,multiple input multiple output(MIN1O)system and Wood-Berry tower industry are investigated.The identification accuracy and the time-series variable selection results are analyzed and compared between NNG and ordinary least square(OLS)algorithms.The derived excellent results show that the proposed NNG-based modeling algorithm can be utilized for simultaneous identification of the model structure,parameters and time-delay with high precision. 展开更多
关键词 Model structure model parameter TIME-DELAY non-negative garrote variable selection.
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ISAR target recognition based on non-negative sparse coding
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作者 Ning Tang Xunzhang Gao Xiang Li 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2012年第6期849-857,共9页
Aiming at technical difficulties in feature extraction for the inverse synthetic aperture radar (ISAR) target recognition, this paper imports the concept of visual perception and presents a novel method, which is ba... Aiming at technical difficulties in feature extraction for the inverse synthetic aperture radar (ISAR) target recognition, this paper imports the concept of visual perception and presents a novel method, which is based on the combination of non-negative sparse coding (NNSC) and linear discrimination optimization, to recognize targets in ISAR images. This method implements NNSC on the matrix constituted by the intensities of pixels in ISAR images for training, to obtain non-negative sparse bases which characterize sparse distribution of strong scattering centers. Then this paper chooses sparse bases via optimization criteria and calculates the corresponding non-negative sparse codes of both training and test images as the feature vectors, which are input into k neighbors classifier to realize recognition finally. The feasibility and robustness of the proposed method are proved by comparing with the template matching, principle component analysis (PCA) and non-negative matrix factorization (NMF) via simulations. 展开更多
关键词 inverse synthetic aperture radar (ISAR) PRE-PROCESSING non-negative sparse coding (NNSC) visual percep-tion target recognition.
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Prognostic model for prostate cancer based on glycolysis-related genes and non-negative matrix factorization analysis
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作者 ZECHAO LU FUCAI TANG +6 位作者 HAOBIN ZHOU ZEGUANG LU WANYAN CAI JIAHAO ZHANG ZHICHENG TANG YONGCHANG LAI ZHAOHUI HE 《BIOCELL》 SCIE 2023年第2期339-350,共12页
Background:Establishing an appropriate prognostic model for PCa is essential for its effective treatment.Glycolysis is a vital energy-harvesting mechanism for tumors.Developing a prognostic model for PCa based on glyc... Background:Establishing an appropriate prognostic model for PCa is essential for its effective treatment.Glycolysis is a vital energy-harvesting mechanism for tumors.Developing a prognostic model for PCa based on glycolysis-related genes is novel and has great potential.Methods:First,gene expression and clinical data of PCa patients were downloaded from The Cancer Genome Atlas(TCGA)and Gene Expression Omnibus(GEO),and glycolysis-related genes were obtained from the Molecular Signatures Database(MSigDB).Gene enrichment analysis was performed to verify that glycolysis functions were enriched in the genes we obtained,which were used in nonnegative matrix factorization(NMF)to identify clusters.The correlation between clusters and clinical features was discussed,and the differentially expressed genes(DEGs)between the two clusters were investigated.Based on the DEGs,we investigated the biological differences between clusters,including immune cell infiltration,mutation,tumor immune dysfunction and exclusion,immune function,and checkpoint genes.To establish the prognostic model,the genes were filtered based on univariable Cox regression,LASSO,and multivariable Cox regression.Kaplan–Meier analysis and receiver operating characteristic analysis validated the prognostic value of the model.A nomogram of the risk score calculated by the prognostic model and clinical characteristics was constructed to quantitatively estimate the survival probability for PCa patients in the clinical setting.Result:The genes obtained from MSigDB were enriched in glycolysis functions.Two clusters were identified by NMF analysis based on 272 glycolysis-related genes,and a prognostic model based on DEGs between the two clusters was finally established.The prognostic model consisted of LAMPS,SPRN,ATOH1,TANC1,ETV1,TDRD1,KLK14,MESP2,POSTN,CRIP2,NAT1,AKR7A3,PODXL,CARTPT,and PCDHGB2.All sample,training,and test cohorts from The Cancer Genome Atlas(TCGA)and the external validation cohort from GEO showed significant differences between the high-risk and low-risk groups.The area under the ROC curve showed great performance of this prognostic model.Conclusion:A prognostic model based on glycolysis-related genes was established,with great performance and potential significance to the clinical application. 展开更多
关键词 GLYCOLYSIS Prostate cancer Tumor immune non-negative matrix factorization Prognostic model
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Alzheimer’s disease classification based on sparse functional connectivity and non-negative matrix factorization
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作者 Li Xuan Lu Xuesong Wang Haixian 《Journal of Southeast University(English Edition)》 EI CAS 2019年第2期147-152,共6页
A novel framework is proposed to obtain physiologically meaningful features for Alzheimer's disease(AD)classification based on sparse functional connectivity and non-negative matrix factorization.Specifically,the ... A novel framework is proposed to obtain physiologically meaningful features for Alzheimer's disease(AD)classification based on sparse functional connectivity and non-negative matrix factorization.Specifically,the non-negative adaptive sparse representation(NASR)method is applied to compute the sparse functional connectivity among brain regions based on functional magnetic resonance imaging(fMRI)data for feature extraction.Afterwards,the sparse non-negative matrix factorization(sNMF)method is adopted for dimensionality reduction to obtain low-dimensional features with straightforward physical meaning.The experimental results show that the proposed framework outperforms the competing frameworks in terms of classification accuracy,sensitivity and specificity.Furthermore,three sub-networks,including the default mode network,the basal ganglia-thalamus-limbic network and the temporal-insular network,are found to have notable differences between the AD patients and the healthy subjects.The proposed framework can effectively identify AD patients and has potentials for extending the understanding of the pathological changes of AD. 展开更多
关键词 Alzheimer's disease sparse representation non-negative matrix factorization functional connectivity
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