期刊文献+
共找到74,500篇文章
< 1 2 250 >
每页显示 20 50 100
Non-linear relationship between built environment and active travel:a hybrid model considering spatial heterogeneity
1
作者 Lexuan Liu Ye Li +1 位作者 Dominique Gruyer Meiting Tu 《International Journal of Transportation Science and Technology》 2025年第3期175-192,共18页
Exploring the mechanisms between the built environment and active travel is crucial for promoting green transportation and fostering the sustainable development of cities.Existing literature focuses on the correlation... Exploring the mechanisms between the built environment and active travel is crucial for promoting green transportation and fostering the sustainable development of cities.Existing literature focuses on the correlation between the built environment and active travel in urban centers,with limited studies on suburban environments,ignoring the implications of spatial heterogeneity.This study conducts a comprehensive spatio-temporal analysis of the active travel behavior of suburban residents,and investigates the nonlinear relationship between the suburban built environment and active travel.A novel hybrid modeling framework that combines extreme gradient boosting(XGBoost)and multi-scale geographic weighted regression(MGWR)is introduced to forecast suburban active travel demand with the consideration of the nonlinearity and spatial heterogeneity in parameter estimates.Shapley additive explanation(SHAP)is used to elucidate the non-linear relationship between built environment variables and active travel.The results indicate that the proposed hybrid model performs the best with high predictive power and interpretability.The density of tourist attractions,transportation facilities,and household properties emerge as the three most influential factors affecting residents’active travel behavior.Social-economic attributes contribute 15.70%to the prediction,while three categories of built environment variables(accessibility,transportation facilities,and land use)contribute 7.31%,5.13%,and 71.87%,respectively.The hybrid model appears to be effective in identifying the nonlinear relationship and threshold effects between built environment variables and active travel.Besides,the model provides actionable insights into designing sustainable and efficient suburban environments,supporting targeted planning and policy-making efforts. 展开更多
关键词 Active travel Built environment Nonlinear relationship Spatial heterogeneity Hybrid model
在线阅读 下载PDF
Lagged effects of risk factors on the disability of older adults:A distributed lag non-linear model approach
2
作者 Yitong Mao Zhiting Guo +2 位作者 Wen Gao Yuping Zhang Jingfen Jin 《International Journal of Nursing Sciences》 2026年第1期53-60,I0004,I0005,共10页
Objectives This study aimed to explore the lagged and cumulative effects of risk factors on disability in older adults using distributed lag non-linear models(DLNMs).Methods We utilized data from the China Health and ... Objectives This study aimed to explore the lagged and cumulative effects of risk factors on disability in older adults using distributed lag non-linear models(DLNMs).Methods We utilized data from the China Health and Retirement Longitudinal Study(CHARLS).After feature selection via Elastic Net Regularization,we applied DLNMs to evaluate the lagged effects of risk factors.Disability was defined as the presence of any difficulties in basic activities of daily living(BADL).The cumulative relative risk(CRR)was calculated by summing the lag-specific risk estimates,representing the cumulative disability risk over the specified lag period.Effect modifications and sensitivity analyses were also performed.Results This study included a total of 2,318 participants.Early-phase lag factors,such as the difficulty in stooping(CRR=3.58;95%CI:2.31-5.55;P<0.001)and walking(CRR=2.77;95%CI:1.39-5.55;P<0.001),exerted the strongest effects immediately upon occurrence.Mid-phase lag factors,such as arthritis(CRR=1.51;95%CI:1.10-2.06;P=0.001),showed a resurgence in disability risk within 2-3 years.Late-phase lag factors,including depressive symptoms(CRR=2.38;95%CI:1.30-4.35;P<0.001)and elevated systolic blood pressure(CRR=1.64;95%CI:1.06-2.79;P=0.02),exhibited significant long-term cumulative risks.Conversely,grip strength(CRR=0.80;95%CI:0.54-0.95;P=0.02)and social participation(CRR=0.89;95%CI:0.73-0.99;P=0.04)were significant protective factors.Conclusions The findings underscore the importance of tailored interventions that account for various lag characteristics of different factors to effectively mitigate disability risk.Future studies should explore the underlying biological and sociological mechanisms of these lagged effects,identify intervention strategies that target risk factors with different lagged patterns,and evaluate their effectiveness. 展开更多
关键词 Ageing DISABILITY Distributed lag non-linear models Nusing Risk factors
暂未订购
Alternative Lens to Understand the Relationships Between Neighborhood Environment and Well-being with Capability Approach and Explainable Artificial Intelligence
3
作者 JIAO Linshen ZHANG Min +4 位作者 ZHEN Feng QIN Xiao CHEN Peipei ZHANG Shanqi HU Yuchen 《Chinese Geographical Science》 2025年第3期472-491,共20页
The relationship between the neighborhood environment and well-being is attracting increasingly attention from researchers and policymakers,as the goal of development has shift from economy to well-being.However,exist... The relationship between the neighborhood environment and well-being is attracting increasingly attention from researchers and policymakers,as the goal of development has shift from economy to well-being.However,existing literature predominantly adopts the utilitarian approach,understanding well-being as people’s feelings about their lives and viewing the neighborhood environment as resources that benefit well-being.The Capability Approach,a novel approach that conceptualize well-being as the freedoms to do or to be and regard environment as conversion factors that influence well-being,can offer new lens by incorporating human development in-to these topics.This paper proposes an alternative theoretical framework:well-being is conceptualized and measured by capability;neighborhood environment affects well-being by providing spatial services,functioning as environmental conversion factors,and serving as social conversion factors.We conducted a case study of Changshu City located in eastern China,utilizing multiple resource data,applying explainable artificial intelligence(XAI),namely eXtreme Gradient Boosting(XGBoost)and SHapley Additive exPlana-tions(SHAP).Our findings highlight the significance of viewing the neighborhood environment as a set of conversion factors,as it provides more explanatory power than providing spatial services.Compared to conventional research based on linear relationship as-sumption,our results demonstrate that the effects of neighborhood environment on well-being are non-linear,characterized by threshold effects and interaction effects.These insights are crucial for informing urban planning and public policy.This research enriches our un-derstanding of well-being,neighborhood environment,and their relationship as well as provides empirical evidence for the core concept of conversion factors in the capability approach. 展开更多
关键词 WELL-BEING neighborhood environment capability approach non-linear relationship explainable artificial intelligence(XAI)
在线阅读 下载PDF
The Relationship between Energy Consumption and Economic Growth in the USA: A Non-Linear ARDL Bounds Test Approach 被引量:1
4
作者 Arzu Tay Bayramoglu Ertugrul Yildirim 《Energy and Power Engineering》 2017年第3期170-186,共17页
We study the relationship between energy consumption and economic growth in the case of USA by using an asymmetric ARDL bounds test approach to achieve the actual model. The quarterly data set covers the period of 197... We study the relationship between energy consumption and economic growth in the case of USA by using an asymmetric ARDL bounds test approach to achieve the actual model. The quarterly data set covers the period of 1973:1- 2013:4. The findings indicate that the effect of energy consumption is asymmetric in the long term but not in the short term. In the long run, the effect of negative component of energy consumption on economic growth is small and statistically insignificant. The coefficient of the positive component of energy consumption is found about 0.9 and statistically significant at 1% level. We conclude that energy saving policies such as technological progress and organizational rearrangements may have the dimmer effect for the impact of a negative component of energy consumption and the booster effect for impact of the positive component of energy consumption. Thus, energy saving policy should be tightly followed by the goal of high economic growth. 展开更多
关键词 Energy CONSUMPTION Economic Growth non-linear ARDL BOUNDS Test USA
暂未订购
Construction of a Maritime Knowledge Graph Using GraphRAG for Entity and Relationship Extraction from Maritime Documents 被引量:3
5
作者 Yi Han Tao Yang +2 位作者 Meng Yuan Pinghua Hu Chen Li 《Journal of Computer and Communications》 2025年第2期68-93,共26页
In the international shipping industry, digital intelligence transformation has become essential, with both governments and enterprises actively working to integrate diverse datasets. The domain of maritime and shippi... In the international shipping industry, digital intelligence transformation has become essential, with both governments and enterprises actively working to integrate diverse datasets. The domain of maritime and shipping is characterized by a vast array of document types, filled with complex, large-scale, and often chaotic knowledge and relationships. Effectively managing these documents is crucial for developing a Large Language Model (LLM) in the maritime domain, enabling practitioners to access and leverage valuable information. A Knowledge Graph (KG) offers a state-of-the-art solution for enhancing knowledge retrieval, providing more accurate responses and enabling context-aware reasoning. This paper presents a framework for utilizing maritime and shipping documents to construct a knowledge graph using GraphRAG, a hybrid tool combining graph-based retrieval and generation capabilities. The extraction of entities and relationships from these documents and the KG construction process are detailed. Furthermore, the KG is integrated with an LLM to develop a Q&A system, demonstrating that the system significantly improves answer accuracy compared to traditional LLMs. Additionally, the KG construction process is up to 50% faster than conventional LLM-based approaches, underscoring the efficiency of our method. This study provides a promising approach to digital intelligence in shipping, advancing knowledge accessibility and decision-making. 展开更多
关键词 Maritime Knowledge Graph GraphRAG Entity and relationship Extraction Document Management
在线阅读 下载PDF
Relationship between the use of smart medical services and mental health status
6
作者 Elif Sarac 《World Journal of Psychiatry》 SCIE 2025年第1期21-25,共5页
In this editorial,I comment on the article by Zhang et al.To emphasize the importance of the topic,I discuss the relationship between the use of smart medical devices and mental health.Smart medical services have the ... In this editorial,I comment on the article by Zhang et al.To emphasize the importance of the topic,I discuss the relationship between the use of smart medical devices and mental health.Smart medical services have the potential to positively influence mental health by providing monitoring,insights,and inter-ventions.However,they also come with challenges that need to be addressed.Understanding the primary purpose for which individuals use these smart tech-nologies is essential to tailoring them to specific mental health needs and prefe-rences. 展开更多
关键词 Smart devices Medical service USAGE PEOPLE relationship Mental health status
暂未订购
Intentional self-regulation and peer relationship in the teacher-student relationship for learning engagement: A moderation–mediation analysis
7
作者 Mengjun Zhu Xing’an Yao Mansor Bin Abu Talib 《Journal of Psychology in Africa》 2025年第1期83-90,共8页
This study investigated the role of intentional self-regulation and the moderating role of peer relationship in the relationship between teacher-student relationship and learning engagement.The study sample comprised ... This study investigated the role of intentional self-regulation and the moderating role of peer relationship in the relationship between teacher-student relationship and learning engagement.The study sample comprised 540 Chinese senior secondary school students between the ages of 15–18(51.67%boys;Mage=16.56 years;SDage=0.90).They completed surveys on the Teacher-Student Relationship Scale,the Selection,Optimization,and Compensation(SOC)Scale,the Peer Relationship Scale for Children and Adolescents,and the Learning Engagement Scale.The results following regression analysis showed that teacher-student relationship predicted higher learning engagement among senior secondary school students.Intentional self-regulation partially mediated the link between teacher-student relationship and learning engagement for higher learning engagement.Peer relationship moderated the relationships between teacher-student relationship and learning engagement and moderated the relationship between teacher-student relationship and intentional self-regulation for higher learning engagement.Thesefindings imply learning engagement can be enhanced by optimizing teacher-student relationship and strengthening intentional self-regulation interventions. 展开更多
关键词 teacher-student relationship intentional self-regulation peer relationship learning engagement
在线阅读 下载PDF
Space cannot substitute for time in the study of the ecosystem services-human wellbeing relationship
8
作者 Lumeng Liu Jianguo Wu 《Geography and Sustainability》 2025年第2期57-68,共12页
The relationship between ecosystem services(ES)and human well-being(HWB)is fundamental to the science and practice of sustainability.However,studies have shown conflicting results,which has been attributed to the infl... The relationship between ecosystem services(ES)and human well-being(HWB)is fundamental to the science and practice of sustainability.However,studies have shown conflicting results,which has been attributed to the influences of indicators,contexts,and scales.Yet,another potential factor,which has been overlooked,may be the mixed use of spatial and temporal approaches.Using twelve ES and seven well-being indicators and multiple statistical methods,we quantified and compared the spatial and temporal ES–HWB relationships for Inner Mongolia,China.The spatial and temporal relationships differed in both correlation direction and strength.Most relationships of economic and employment-related indicators with food provisioning and supporting services were temporally positive but spatially nonsignificant or negative.Some relationships of economic and employmentrelated indicators with water retention,sandstorm prevention,and wind erosion were temporally negative but spatially complex.However,the spatial and temporal ES–HWB relationships could also be similar in some cases.We conclude that although both the spatial and temporal approaches have merits,space generally cannot substitute for time in the study of ES–HWB relationship.Our study helps reconcile the seemingly conflicting findings in the literature,and suggests that future studies should explicitly distinguish between the spatial and temporal ES–HWB relationships. 展开更多
关键词 Ecosystem services Objective human well-being Space-for-time substitution Spatial relationship Temporal relationship
在线阅读 下载PDF
Teacher-student relationship quality effects on school students’bullying victimization:A serial mediation model by student-student relationship and student engagement
9
作者 Yuan Yuan Yanfei Yang 《Journal of Psychology in Africa》 2025年第4期541-548,共8页
This study examined the impact of teacher-student relationship quality on students’risk of bullying victimiza-tion and the mediating roles of student-student relationships and student engagement in this relationship.... This study examined the impact of teacher-student relationship quality on students’risk of bullying victimiza-tion and the mediating roles of student-student relationships and student engagement in this relationship.A total of 656 Chinese junior high school students(females=361,mean age=13.75,SD=0.98)completed validated measures of teacher-student relationship quality,student-student relationship quality,student engagement,and bullying victimization.Regression analysis results indicated that higher teacher-student relationship quality predicted a lower risk of student bullying victimization.Serial mediating effect testing of the student-student relationship quality and student engagement revealed that these factors fully mediated the relationship between teacher-student relationship quality and bullying victimization,resulting in a lower risk of bullying victimization.The results showed that student-student relationship quality had a more substantial mediating effect than student engagement.Thefindings support the Socio-Ecological Framework,suggesting that within the Microsystem,interactions between individuals and their immediate environments significantly impact their behavior.Specifically,thesefindings suggest that good teacher-student relationships can enhance the quality of student-student relationships and student engagement,thereby preventing and reducing the occurrence of bullying victimization. 展开更多
关键词 teacher-student relationship quality bullying victimization student-student relationship quality student engagement junior middle school students
在线阅读 下载PDF
Discussion of“Prediction of the undrained shear strength of remolded soil with non-linear regression,fuzzy logic,and artificial neural network”[J.Mt.Sci.21(9):3108–3122]
10
作者 Amin SOLTANI Brendan C.O’KELLY 《Journal of Mountain Science》 2025年第7期2723-2730,共8页
This opinion article discusses the original research work of Yünkül et al.(the Authors)published in the Journal of Mountain Science 21(9):3108–3122.Employing non-linear regression,fuzzy logic and artificial... This opinion article discusses the original research work of Yünkül et al.(the Authors)published in the Journal of Mountain Science 21(9):3108–3122.Employing non-linear regression,fuzzy logic and artificial neural network modeling techniques,the Authors interrogated a large database assembled from the existing research literature to assess the performance of twelve equation rules in predicting the undrained shear strength(s_(u))mobilized for remolded fine-grained soils at different values of liquidity index(I_(L))and water content ratio.Based on their analyses,the Authors proposed a simple and reportedly reliable correlation(i.e.,Eq.9 in their paper)for predicting s_(u) over the I_(L) range of 0.15 to 3.00.This article describes various shortcomings in the Authors’assembled database(including potentially anomalous data and covering an excessively wide I_(L) range in relation to routine geotechnical and transportation engineering applications)and their proposed s_(u)=f(I_(L))correlation.Contrary to the Authors’assertions,their proposed correlation is not reliable for fine-grained soils with consistencies in the general firm to stiff range(i.e.,for 0.15<I_(L)<0.40),increasingly overestimating s_(u) for reducing I_(L),and eventually predicting s_(u)→+∞for I_(L)→0.15+(while producing mathematically undefined s_(u) for I_(L)<0.15),thus rendering their correlation unconservative and potentially leading to unsafe geotechnical designs.Exponential or regular-power type s_(u)=f(I_(L))models are more s_(u)itable when developing correlations that are applicable over the full plastic range(of 0<I_(L)<1),thereby providing reasonably conservative s_(u) predictions for use in the preliminary design for routine geotechnical engineering applications. 展开更多
关键词 Undrained shear strength Liquidity index Soil consistency non-linear regression
原文传递
Revealing inconsistency of the sediment-water relationships in the Brahmaputra River:A comparative analysis of upstream and downstream cross-sections
11
作者 RAHIM Md Abdur LIU Shuang +3 位作者 HU Kaiheng LI Hao ISLAM Maksudul HOSSAIN Sazzad 《Journal of Mountain Science》 2025年第8期2819-2836,共18页
Understanding the relationship between sediment and discharge is crucial for effective river management and water-sediment modeling,especially in the Brahmaputra River,one of the large transboundary rivers with high s... Understanding the relationship between sediment and discharge is crucial for effective river management and water-sediment modeling,especially in the Brahmaputra River,one of the large transboundary rivers with high sediment and discharge variability in South Asia.Current knowledge of sediment-water relations is constrained by limited data,hindering effective transboundary river management.Using multivariate linear regression,climate elasticity coefficient,and traditional sediment rating curve,this study is designed to compare the sediment-water relations of the upstream(Nuxia)and the downstream(Bahadurabad).The results reveal significant variability between the two stations.In the upstream Nuxia,the simulation strongly correlates with observed suspended sediment load(SSL)and discharge(Q)(Pearson's r of 0.62 and 0.68,respectively).Conversely,at downstream Bahadurabad,weaker correlations(r=0.31 for sediment and r=0.51 for discharge simulation)indicate a reduced relation.This contrast reflects the non-linear nature of sediment-discharge coupling along the river continuum,shaped by both climatic and anthropogenic influences.Elasticity(ε)analysis highlights the dominant role of precipitation in shaping sediment-water dynamics(εP-SSL=2.53,εP-Q=1.01)at Nuxia,while Bahadurabad(εP-SSL=0.41,εP-Q=0.82)reflects a reduced sensitivity,possibly due to sediment retention along the floodplain.Air temperature elasticity(εT-SSL,-0.15&-3.06 at Nuxia and Bahadurabad,respectively)reveals contrasting impacts,strongly negatively influencing sediment transport at Bahadurabad.These findings highlight the significance of spatial variability and climatic influences on sediment dynamics,underscoring the necessity for site-specific management strategies.The sediment rating curve(SRC)analysis reveals a strong relationship between sediment and discharge(R^(2)=0.88)at Nuxia and a relatively weaker relationship(R^(2)=0.14)at Bahadurabad,which demonstrates a lower sedimentdischarge coupling that could be affected by downstream factors such as sediment deposition,channel morphology,and anthropogenic activities.This study offers valuable insights into sediment-water dynamics,highlighting the importance of understanding nonlinear relationships in the Brahmaputra River. 展开更多
关键词 Sediment-water relation Climate elasticity non-linear change Transboundary river The Brahmaputra
原文传递
Research on the Relationship Between Islam and Chinese Culture
12
作者 Alimtohte Shiho 《Cultural and Religious Studies》 2025年第1期1-11,共11页
Since China’s reform and development,under the influence of the global religious and cultural boom,it has also focused on studying Islamic culture and related fields,resulting in many important representative works.T... Since China’s reform and development,under the influence of the global religious and cultural boom,it has also focused on studying Islamic culture and related fields,resulting in many important representative works.The main characteristic of writing books in this area is to use popular knowledge materials that are suitable for various sectors of society.There are also works exploring the historical evolution of Islamic culture in China,which involve the relationship between Islamic culture and traditional Chinese culture.Before the 1980s,there were no significant achievements in publishing papers.However,since the 1990s,there has been a noticeable increase in papers related to Islamic culture and related fields,with new advances in research areas and methods.There are both articles that explore the attributes and characteristics of Islamic culture from the perspectives of world history and culture,as well as many articles that explore various specific aspects of Islamic culture from the perspective of specific topics.In this article,the author collects academic achievements in the study of Islamic culture in China and introduces them to the academic community,letting them know about China's research on world Islamic culture. 展开更多
关键词 China Islamic world Islamic Culture RESEARCH relationship
在线阅读 下载PDF
Non-Linear Increase of the Real Contact Area of PMMA Blocks and the Related Contact Model
13
作者 Zhijun Luo Kai Wu Shaoze Yan 《Chinese Journal of Mechanical Engineering》 2025年第1期261-272,共12页
Many experiments have supported the contact models,such as the GW and MB models,but the majority of previous validations have been performed under light loads,resulting in a linear relationship between normal force an... Many experiments have supported the contact models,such as the GW and MB models,but the majority of previous validations have been performed under light loads,resulting in a linear relationship between normal force and contact area.However,the real contact area fraction should never equal one;there must be a limit smaller than the apparent area,implying that the real contact area cannot increase linearly indefinitely.In this paper,the real contact area between two polymethylmethacrylate(PMMA)blocks under heavy load is measured using the total reflection method,and the contact area is analyzed using the image processing method.The results show that the real contact area increases with normal load linearly in light loads but non-linearly in heavy loads;the number of contact spots increases with load linearly in light loads but also non-linearly in heavy loads,synchronous with the change in the real contact area.The GW,MB,and Zhao,Maietta,and Chang(ZMC)models were used to predict the experiment results,but none of them predicted the non-linear stage.A revised GW model based on the bulk deformation hypothesis performs better in predicting the non-linear stage.The study’s findings can be applied to PMMA or other similar materials,and they can serve as a useful reference for future research on the contact mechanisms of other materials. 展开更多
关键词 Real contact area GW model MB model Total reflection non-linear increase
在线阅读 下载PDF
A rapid analysis method to discover antioxidant active components and mechanisms in soybean:untargeted metabolomics combined with network pharmacology and spectrum-effect relationship-component knockout-identification techniques
14
作者 Xuqiang Liu Xinjing Meng +3 位作者 Dongqi Liu Junshang Liu Mengqi Lan Wenyi Kang 《Food Science and Human Wellness》 2025年第9期3753-3763,共11页
Soybean is widely used in diets,and numerous reports have highlighted its antioxidant properties.However,constructing a methodology for rapid identifying and predicting a series of antioxidant active ingredients in So... Soybean is widely used in diets,and numerous reports have highlighted its antioxidant properties.However,constructing a methodology for rapid identifying and predicting a series of antioxidant active ingredients in Soybean presents certain challenges.Therefore,we introduced the spectrum-effect relationship-ingredient knockout identification technique to identify a series of antioxidant active ingredients in soybean.By combining untargeted metabolomics with network pharmacology,we predicted the antioxidant active ingredients and their target sites.We successfully identified 4 antioxidant active compounds(daidzein,genistein,daidzein,and glycitin)and 10 corresponding antioxidant targets(epidermal growth factor receptor(EGFR),estrogen receptor 1(ESR1),steroid receptor coactivator(SRC),tumor necrosis factor(TNF),kinase insert domain receptor(KDR),AKT serine/threonine kinase 1(AKT1),growth factor receptor bound protein 2(GRB2),signal transducer and activator of transcription1(STAT1),mitogen-activated protein kinase 8(MAPK8),B-cell lymphoma-2(BCL2))by our analysis.The validation results from cell experiments revealed that glycitin exhibited the best antioxidant activity and significantly influenced the expression of EGFR and the proteins associated with nuclear factor erythroid 2-related factor 2/NAD(P)H quinone dehydrogenase 1(NRF2/NQO1)signaling pathways.These findings were consistent with the predicted outcomes and were further confirmed in a zebrafish model.It suggests that glycitin may exert antioxidant effects by regulating the expression of EGFR,NRF2,and NQO1 proteins.The results demonstrate that a rapid analytical method for determining antioxidant activity was established. 展开更多
关键词 SOYBEAN ANTIOXIDANT Metabolomics Network pharmacology Spectrum-Effect relationship
在线阅读 下载PDF
Relationship of diabetes mellitus with prognostic factors in breast cancer
15
作者 Songul Peltek Ozer Fatih Keyif +2 位作者 Ferdi Bolat Bahri Ozer Gulali Aktas 《World Journal of Experimental Medicine》 2025年第3期127-133,共7页
BACKGROUND Hyperglycemia secondary to diabetes can lead to organ failure unless properly controlled,and it is associated with numerous health issues,particularly metabolic problems.Breast cancer is one of the most com... BACKGROUND Hyperglycemia secondary to diabetes can lead to organ failure unless properly controlled,and it is associated with numerous health issues,particularly metabolic problems.Breast cancer is one of the most common malignancies in females worldwide and represents a major health concern due to its morbidity and mortality.The progression of the disease and the response to treatment depend on numerous variables,including both tumor biology and patient-related factors.Key prognostic indicators include age,tumor size,lymph node involvement,histological type,hormone receptor status,and expression of biomarkers such as HER2.AIM To investigate the relationship between preoperative blood glucose levels and cancer prognostic factors in patients diagnosed with breast cancer.METHODS In this study patients diagnosed with breast cancer were classified into two groups:Those with blood glucose levels<125 mg/dL and those with levels>125 mg/dL.Estrogen and progesterone receptor positivity,Ki-67 percentage,Cerb2 positivity,number of positive lymph nodes,and presence of lymphovascular invasion were examined histopathologically.RESULTS The study included 246 patients with breast cancer:196 were in the normal glucose group and 50 were in the elevated glucose group.In the normal glucose group,68%of the tumors were left-sided and 32%were right-sided,while all tumors in the elevated glucose group were left-sided.This difference was statistically significant(P<0.001).Tumor size,Ki-67,and the number of positive lymph nodes were not associated with blood glucose in patients with breast cancer(P>0.05 for all).However,blood glucose was correlated with age in this population.Correlation analyses revealed that blood glucose was positively correlated with age(r=0.23,P<0.001).Additionally,Ki-67 was correlated with tumor size(r=0.14,P=0.03)and age(r=-0.18,P=0.005).CONCLUSION Our study highlighted the complex interplay between metabolic factors,such as fasting glucose levels,and breast cancer characteristics.Elevated glucose levels were associated with older age.The significant association between tumor laterality and glucose levels underscores the need for further investigation into the collective influence of metabolic and anatomical factors on breast cancer development and progression. 展开更多
关键词 Diabetes mellitus Breast cancer HYPERGLYCEMIA PROGNOSIS relationship
暂未订购
Application of artificial intelligence to quantitative structure-retention relationship calculations in chromatography
16
作者 Jingru Xie Si Chen +1 位作者 Liang Zhao Xin Dong 《Journal of Pharmaceutical Analysis》 2025年第1期4-18,共15页
Quantitative structure-retention relationship(QSRR)is an important tool in chromatography.QSRR examines the correlation between molecular structures and their retention behaviors during chromatographic separation.This... Quantitative structure-retention relationship(QSRR)is an important tool in chromatography.QSRR examines the correlation between molecular structures and their retention behaviors during chromatographic separation.This approach involves developing models for predicting the retention time(RT)of analytes,thereby accelerating method development and facilitating compound identification.In addition,QSRR can be used to study compound retention mechanisms and support drug screening efforts.This review provides a comprehensive analysis of QSRR workflows and applications,with a special focus on the role of artificial intelligence-an area not thoroughly explored in previous reviews.Moreover,we discuss current limitations in RT prediction and propose promising solutions.Overall,this review offers a fresh perspective on future QSRR research,encouraging the development of innovative strategies that enable the diverse applications of QSRR models in chromatographic analysis. 展开更多
关键词 Quantitative structure-retention relationship CHROMATOGRAPHY ACCURACY Machine learning
在线阅读 下载PDF
The Influence of Leisure-Time Physical Activity and Peer Relationships on Cyberbullying among Adolescents:A One-Year Longitudinal Investigation
17
作者 Jingtao Wu Yanhong Shao +1 位作者 Wanli Zang Jun Hu 《International Journal of Mental Health Promotion》 2025年第5期717-735,共19页
Background With the rapid growth of internet usage,adolescent cyberbullying has become a pressing issue.This study examines the longitudinal impact of leisure-time physical activity and peer relationships on cyberbull... Background With the rapid growth of internet usage,adolescent cyberbullying has become a pressing issue.This study examines the longitudinal impact of leisure-time physical activity and peer relationships on cyberbullying over a one-year period,drawing on the Stage-Environment Fit Theory and the Interpersonal Relationship Theory.Methods A three-wave longitudinal study was conducted over one year,involving 896 middle school students from five schools in Sichuan,Jiangsu,and Guangdong,China,selected to ensure regional diversity.Participants were recruited using stratified random sampling,and data were collected at four-month intervals.Leisure-time physical activity,peer relationships,and cyberbullying behaviors were assessed using validated scales.Data were analyzed using latent growth modeling(LGM)and structural equation modeling(SEM)to examine longitudinal effects and mediation relationships.Results(1)Leisure-time physical activity,peer relationships,and cyberbullying behaviors remained relatively stable over time.(2)Both leisure-time physical activity and peer relationships significantly reduced future cyberbullying incidents,with physical activity also enhancing subsequent peer relationships.(3)Peer relationships partially mediated the effect of leisure-time physical activity on cyberbullying,indicating that improved peer interactions contributed to a reduction in cyberbullying behaviors.Conclusion This study found that leisure-time sports activities and peer relationships are important factors affecting cyberbullying,and peer relationships play a partial mediating role in it.The results provide empirical support for understanding the formation mechanism and influencing factors of cyberbullying. 展开更多
关键词 LEISURE-TIME physical activity CYBERBULLYING peer relationships adolescents
在线阅读 下载PDF
Enhancing yield strength and quantifying relationship with microstructure in magnesium alloys through work hardening
18
作者 Xiaoyu Wang Wenzhen Chen +5 位作者 Yang Yu Wenjie Wu Wenke Wang Daqing Fang Wencong Zhang Jun Sun 《Journal of Magnesium and Alloys》 2025年第6期2581-2590,共10页
This paper explored how the work hardening process enhances the yield strength(YS)of magnesium alloy and established a novel quantitative relationship between microstructure and YS.The YS of an extruded Mg–Nd–Zn–Zr... This paper explored how the work hardening process enhances the yield strength(YS)of magnesium alloy and established a novel quantitative relationship between microstructure and YS.The YS of an extruded Mg–Nd–Zn–Zr alloy was nearly tripled by rotary swaging at 200℃,attributing to dislocation accumulation,grain fragmentation,and basal texture formation.A modified Hall–Petch relationship(GM–HP)was established by introducing the equivalent orientation factor and dislocation density to accurately quantify the YS and the contribution of each strengthening mechanism.The contributions of dislocation hardening and grain boundary strengthening were multiplied by the strong basal texture.This paper offered valuable insights and guidance for designing and optimizing high-strength wrought magnesium alloys and their plastic processing methods. 展开更多
关键词 Work hardening TEXTURE DISLOCATION GM-HP relationship
在线阅读 下载PDF
Buckling morphology evolution of thin films on non-linear elastic substrates
19
作者 Andi Lai Di Ou +1 位作者 Jun Liao Guo Fu 《Acta Mechanica Sinica》 2025年第2期176-183,共8页
Organisms have evolved a strain limiting mechanism,reflected as a non-linear elastic constitutive,to prevent large deformations from threatening soft tissue integrity.Compared with linear elastic substrates,the wrinkl... Organisms have evolved a strain limiting mechanism,reflected as a non-linear elastic constitutive,to prevent large deformations from threatening soft tissue integrity.Compared with linear elastic substrates,the wrinkle of films on non-linear elastic substrates has received less attention.In this article,a unique wrinkle evolution of the film-substrate system with a J-shaped non-linear stress-strain relation is reported.The result shows that a concave hexagonal array pattern is formed with the shrinkage strain of the film-substrate systems developing.As the interconnection of hexagonal arrays,a unit cell ridge network appears with properties such as chirality and helix.The subparagraph maze pattern formed with high compression is mainly composed of special single-cell ridge networks such as spiral single cores,chiral double cores,and combined multi-cores.This evolutionary model is highly consistent with the results of experiments,and it also predicts wrinkle morphology that has not yet been reported.These findings can serve as a novel explanation for the surface wrinkle of biological soft tissue,as well as provide references for the preparation of artificial biomaterials and programmable soft matter. 展开更多
关键词 non-linear elastic substrate Chiral ridge Spiral unit cell Tension-compression asymmetry Wrinkle morphological evolution
原文传递
Determining the Relationship Between Change of Direction Speed and Agility in Team Sport Athletes:Meta-Analysis
20
作者 Rafael Carvajal-Espinoza Scott Talpey Walter Salazar-Rojas 《Journal of Science in Sport and Exercise》 2025年第3期253-264,共12页
Background Agility and change of direction speed(COD)are essential skills in sports,their development being the focus of training and research.While these terms have been used interchangeably,it is crucial to distingu... Background Agility and change of direction speed(COD)are essential skills in sports,their development being the focus of training and research.While these terms have been used interchangeably,it is crucial to distinguish between agility and COD,as the latter involves a sudden change in direction without the presence of external stimuli.Objective This meta-analysis aims to summarize studies that have included COD and agility tests and explore the potential relationship between these two physical qualities.Method Following the PRISMA guidelines,a meta-analysis was conducted using studies published between 2005 and 2021.All studies identified for inclusion were peer-reviewed and published in English and Spanish,using an athlete population as participants.For all analyses,a significance level was set at P<0.05.Results The meta-analysis,which included 21 studies with 945 participants from various team sports,found a moderate correlation(r=0.46)between agility and COD.This study considers moderator variables such as Age,Sex,Sport,Test Pattern,Test Combination,and Agility Stimulus.Conclusion The results of this study revealed that while COD and agility have commonalities,these two constructs represent distinct different qualities.Younger participants show a stronger correlation between the two,emphasizing age-related differences in physical development.Coaches should consider these findings in designing training programs and assessments,tailoring approaches based on the specific demands of each skill.The study contributes valuable insights into the nuanced relationship between agility and COD in team sports. 展开更多
关键词 AGILITY Change of direction Performance relationship Team sports Correlation
原文传递
上一页 1 2 250 下一页 到第
使用帮助 返回顶部