期刊文献+
共找到512,653篇文章
< 1 2 250 >
每页显示 20 50 100
On transition of type V interaction in double-wedge flow with non-equilibrium effects
1
作者 Wentao Xiong Yujian Zhu Xisheng Luo 《Theoretical & Applied Mechanics Letters》 CAS CSCD 2016年第6期282-285,共4页
The transition between regular reflection (RR) and Mach reflection (MR) of type V shock-shock interaction on a double-wedge geometry with high temperature non-equilibrium effects is investigated by extended shock-... The transition between regular reflection (RR) and Mach reflection (MR) of type V shock-shock interaction on a double-wedge geometry with high temperature non-equilibrium effects is investigated by extended shock-polar method and numerical simulation. First, the critical angles of transition from detachment criterion and yon Neumann criterion are determined by the extended shock-polar method considering the non-equilibrium effects. Then wave patterns and the transition process are numerically obtained. Results of the critical transition angles from shock-polar calculation and numerical simulation show evident disagreement, indicating transition mechanism between RR and MR of type V interaction is changed. By comparing with the frozen counterpart, it is also found that non-equilibrium effects lead to a larger critical wedge angle and a larger hysteresis interval. 展开更多
关键词 Shock interaction non-equilibrium effects Shock polar Hypersonic flow
在线阅读 下载PDF
Influence of fuel injection position and equivalent mixture ratio on chemical non-equilibrium effects of single expansion ramp nozzle
2
作者 CHENG Cheng WANG Yi-bai +1 位作者 LIU Yu QIN Li-zi 《航空动力学报》 EI CAS CSCD 北大核心 2013年第9期2100-2111,共12页
Chemical non-equilibrium flow was investigated for the scramjet single expansion ramp nozzle(SERN)with a strut-based liquid-kerosene-fueled combustor.Two-dimensional Reynolds-averaged NavierStokes(RANS)equations were ... Chemical non-equilibrium flow was investigated for the scramjet single expansion ramp nozzle(SERN)with a strut-based liquid-kerosene-fueled combustor.Two-dimensional Reynolds-averaged NavierStokes(RANS)equations were solved with the species conservation equation for continuous phase and the renormalization group(RNG)k-εturbulence model.Lagrangian discrete-phase model was analyzed for liquidkerosene droplets behavior in the supersonic stream.Combustion was simulated by kerosene surrogate fuel's10-species and 13-step reduced reaction kinetics mechanism with use of Arrhenius's laminar finite rate model.Parametric studies were carried out to estimate the influence of different fuel injection positions and equivalent mixture ratios on the SERN chemical non-equilibrium effects.Numerical calculation results show that the strutbased combustor enables convenient modeling of various SERN entry conditions,which is similar with many preceding investigations,by changing the injector strut position and controlling the mass flow rate of each injector.Chemical non-equilibrium effects function in the whole SERN,especially in the initial flow expansion region,leads to obviously higher SERN performance of the non-equilibrium flow than that of the frozen flow.Furthermore,the distributed fuel injection pattern plays a significant role in enhancing the combustion efficiency in combustor,but weakening the chemical non-equilibrium effects funciton in SERN.Additionally,while the equivalent mixture ratio increases,the SERN thrust coefficient and lift coefficient rise gradually,and the increment of non-equilibrium flow in relation to frozen flow becomes higher as well.To be specific,the equivalent mixture ratio is 0.6,the maximum increment of thrust coefficient and lift coefficient are 11.6% and 25% respectively. 展开更多
关键词 scramjet engine single expansion ramp nozzle chemical non-equilibrium fuel injection position equivalent mixture ratio
原文传递
Droplet coalescence kinetics:Coalescence mechanisms and thermodynamic non-equilibrium effects under isothermal and non-isothermal conditions
3
作者 Guanglan Sun Yanbiao Gan +2 位作者 Bin Yang Aiguo Xu Zhipeng Liu 《Frontiers of physics》 2025年第6期329-348,共20页
Droplet coalescence is a multiscale phenomenon driven by multiple thermodynamic non-equilibrium(TNE)effects.This study investigates the coalescence mechanisms and the complex interplay between various TNE effects in b... Droplet coalescence is a multiscale phenomenon driven by multiple thermodynamic non-equilibrium(TNE)effects.This study investigates the coalescence mechanisms and the complex interplay between various TNE effects in both isothermal and non-isothermal cases kinetically.The main findings include:(i)Coalescence initiation and cut-through mechanisms:In the non-isothermal case,latent heat release results in a temperature rise that slightly increases the surface tension gradient(driving force)near the contact point,while substantially enhancing the pressure gradient(resistance).This leads to a significantly prolonged initiation of coalescence compared to the isothermal case.The additional temperature field effects introduce greater spatial complexity to both the flow field and morphology.For the cut-through mechanism,in both cases,pressure extends the liquid-vapor interface in opposite directions,promoting liquid bridge growth.(ii)TNE effects:The latent heat-induced temperature rise in the thermal case considerably dampens the intensity of TNE effects.Before and after droplet contact,TNE quantities driven by the temperature gradient(Δ_(3)^(*),1 andΔ_(3)^(*))and those driven by the velocity gradient(Δ_(2)^(*)andΔ_(4)^(*),2),alternate in dominating the coalescence process.This alternating dominance results in a more complex spatiotemporal evolution of TNE effects compared to the isothermal case,where the TNE intensity is dominated byΔ_(2)^(*)andΔ_(4)^(*),2.(iii)Entropy production mechanisms:In the non-isothermal case,entropy production is contributed by bothΔ_(2)^(*)andΔ_(3)^(*),1,with the former being the dominant contributor.The temperature field reduces the entropy production rate,but extends its duration,thereby increasing the total entropy production.The entropy production rates fromΔ_(2)^(*)andΔ_(3)^(*),1 alternate before and after the droplet cut-through.Further investigation into effects of the initial droplet distance rd revealed that it increases droplet cut-through time tc,the time when total TNE reaches its maximum tDmax,and the time when total entropy production rate reaches its maximum tS˙prmax in a power-law manner:(tc,tDmax,tS˙prmax)∼rdα.This research provides kinetic insights into droplet coalescence,offering mesoscopic support for dynamic,cross-scale regulation and multifunctional integration of coalescence processes in industrial applications. 展开更多
关键词 droplet coalescence discrete Boltzmann method non-equilibrium effect entropy production
原文传递
Rarefaction effect on non-equilibrium characteristics of laminar shock wave/boundary layer interaction
4
作者 Jiahui SONG Long MIAO +4 位作者 Aiguo XU Yanbiao GAN Feng CHEN Yugan LIAO Xiao HOU 《Chinese Journal of Aeronautics》 2025年第10期311-326,共16页
A Discrete Boltzmann Method(DBM)with a Maxwell-type boundary condition is constructed to investigate the influence of rarefaction on laminar Shock Wave/Boundary Layer Interaction(SWBLI).Due to the complexity of compre... A Discrete Boltzmann Method(DBM)with a Maxwell-type boundary condition is constructed to investigate the influence of rarefaction on laminar Shock Wave/Boundary Layer Interaction(SWBLI).Due to the complexity of compressible flow,a Knudsen number vector Kn,whose components include the local Knudsen numbers such as Kn_(ρ)and Kn_(U),is introduced to characterize the local structures,where Kn_(ρ)and Kn_(U)are Knudsen numbers defined in terms of the density and velocity interfaces,respectively.Since first focusing on the steady state of SWBLI,the DBM considers up to the second-order Kn_(ρ)(rarefaction/non-equilibrium)effects.The model is validated using Mach number 2 SWBLI and the necessity of using DBM with sufficient physical accuracy is confirmed by the shock collision problem.Key findings include the following:the leading-edge shock wave increases the local density Knudsen number Kn_(ρ)and eventually leads to the failure of linear constitutive relations in the Navier-Stokes(N-S)model and surely also in the lower-order DBM;the non-equilibrium effect differences in regions behind the leading-edge shock wave are primarily correlated with Kn_(ρ),while in the separation region are primarily correlated with Kn_(U);the non-equilibrium quantities D_(2)and D_(4,2),as well as the viscous entropy production rate S_(NOMF)can be used to identify the separation zone.The findings clarify various effects and main mechanisms in different regions associated with SWBLI,which are concealed in N-S model. 展开更多
关键词 Rarefaction effects Discrete Boltzmann method Shock wave/boundary layer interaction Thermodynamic non-equilibrium Kinetic theory
原文传递
Non-equilibrium effect in the allosteric regulation of the bacterial flagellar switch
5
作者 Yuan Junhua (袁军华) Zhang Rongjing (张榕京) 《Science Foundation in China》 CAS 2017年第3期48-48,共1页
Subject Code:A02With funding support from the National Natural Science Foundation of China,the research group led by Prof.Yuan Junhua(袁军华)and Zhang Rongjing(张榕京)from the University of Science and Technology of C... Subject Code:A02With funding support from the National Natural Science Foundation of China,the research group led by Prof.Yuan Junhua(袁军华)and Zhang Rongjing(张榕京)from the University of Science and Technology of China(USTC)has discovered non-equilibrium effect in the regulation of the bacterial flagellar switch, 展开更多
关键词 non-equilibrium effect in the allosteric regulation of the bacterial flagellar switch
原文传递
Investigating the effect of relaxation time on Richtmyer–Meshkov instability under reshock impact:a two-component discrete Boltzmann method study
6
作者 Lingyan Lian Chuandong Lin +1 位作者 Demei Li Huilin Lai 《Communications in Theoretical Physics》 2025年第8期180-195,共16页
The Richtmyer–Meshkov(RM)instability plays an important role in various natural and engineering fields such as inertial confinement fusion.In this study,the effect of relaxation time on the RM instability under resho... The Richtmyer–Meshkov(RM)instability plays an important role in various natural and engineering fields such as inertial confinement fusion.In this study,the effect of relaxation time on the RM instability under reshock impact is investigated using a two-component discrete Boltzmann method.The hydrodynamic and thermodynamic characteristics of the fluid system are comprehensively analyzed from the perspectives of the density gradient,vorticity,kinetic energy,mixing degree,mixing width and non-equilibrium intensity.Simulation results indicate that for longer relaxation time,the diffusion and dissipation are enhanced,the physical gradients decrease,and the growth of the interface is suppressed.Furthermore,the non-equilibrium manifestations show complex patterns,driven by the competitive physical mechanisms of the diffusion,dissipation,shock wave,rarefaction wave,transverse wave and fluid instabilities.These findings provide valuable insight into the fundamental mechanism of compressible fluid flows. 展开更多
关键词 Richtmyer–-Meshkov instability discrete Boltzmann method compressible fluid non-equilibrium effect
原文传递
Catalytic Effect of Activated Carbon and Activated Carbon Fiber in Non-Equilibrium Plasma-Based Water Treatment 被引量:2
7
作者 张延宗 郑经堂 +2 位作者 曲险峰 于维钊 陈宏刚 《Plasma Science and Technology》 SCIE EI CAS CSCD 2008年第3期358-362,共5页
Catalysis and regeneration efficiency of granular activated carbon (GAC) and activated carbon fiber (ACF) were investigated in a non-equilibrium plasma water treatment reactor with a combination of pulsed streamer... Catalysis and regeneration efficiency of granular activated carbon (GAC) and activated carbon fiber (ACF) were investigated in a non-equilibrium plasma water treatment reactor with a combination of pulsed streamer discharge and GAC or ACF. The experimental results show that the degradation efficiency of methyl orange (MO) by the combined treatment can increase 22% (for GAC) and 24% (for ACF) respectively compared to pulsed discharge treatment alone, indicating that the combined treatment has a synergetic effect. The MO degradation efficiency by the combined treatment with pulsed discharge and saturated GAC or ACF can increase 12% and 17% respectively compared to pulsed discharge treatment alone. Both GAC and ACF show catalysis and the catalysis of ACF is prominent. Meanwhile, the regeneration of GAC and ACF are realized in this process. When H202 is introduced into the system, the utilization efficiency of ozone and ultraviolet light is improved and the regeneration efficiency of GAC and ACF is also increased. 展开更多
关键词 non-equilibrium plasma water treatment activated carbon activated carbon fiber catalytic effect
在线阅读 下载PDF
Effect of La_2O_3/γAl_2O_3 Catalyst on the Activation of CH_4 and CO_2 to C_02 Hydrocarbons under Non-equilibrium Plasma 被引量:3
8
作者 XiuLingZHANG WeiMinGONG 《Chinese Chemical Letters》 SCIE CAS CSCD 2002年第2期175-176,共2页
In the reaction of methane and carbon dioxide to C2 hydrocarbons under non-equilibrium plasma, methane conversion was decreased, but selectivity of C2 hydrocarbons was increased when using La2O3/?Al2O3 as catalyst. S... In the reaction of methane and carbon dioxide to C2 hydrocarbons under non-equilibrium plasma, methane conversion was decreased, but selectivity of C2 hydrocarbons was increased when using La2O3/?Al2O3 as catalyst. So the yield of C2 hydrocarbons was higher than using plasma alone. The synergism of La2O3/?Al2O3 and plasma gave methane conversion of 24.9% and C2 yield of 18.1%. The distribution of C2 hydrocarbons changed when Pd- La2O3/?Al2O3 was used as catalyst, the major C2 product was ethylene. 展开更多
关键词 non-equilibrium plasma CATALYST METHANE carbon dioxide.
在线阅读 下载PDF
Effect of Co on Solidification Characteristics and Microstructural Transformation of Non-equilibrium Solidified Cu-Ni Alloys
9
作者 安红恩 Bih-Lii Chua +1 位作者 Ismail Saad Willey Yun Hsien Liew 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2024年第2期444-453,共10页
Non-equilibrium solidification structures of Cu55Ni45 and Cu55Ni43Co2 alloys were prepared by the molten glass purification cycle superheating method.The variation of the recalescence phenomenon with the degree of und... Non-equilibrium solidification structures of Cu55Ni45 and Cu55Ni43Co2 alloys were prepared by the molten glass purification cycle superheating method.The variation of the recalescence phenomenon with the degree of undercooling in the rapid solidification process was investigated using an infrared thermometer.The addition of the Co element affected the evolution of the recalescence phenomenon in Cu-Ni alloys.The images of the solid-liquid interface migration during the rapid solidification of supercooled melts were captured by using a high-speed camera.The solidification rate of Cu-Ni alloys,with the addition of Co elements,was explored.Finally,the grain refinement structure with low supercooling was characterised using electron backscatter diffraction(EBSD).The effect of Co on the microstructural evolution during nonequilibrium solidification of Cu-Ni alloys under conditions of small supercooling is investigated by comparing the microstructures of Cu55Ni45 and Cu55Ni43Co2 alloys.The experimental results show that the addition of a small amount of Co weakens the recalescence behaviour of the Cu55Ni45 alloy and significantly reduces the thermal strain in the rapid solidification phase.In the rapid solidification phase,the thermal strain is greatly reduced,and there is a significant increase in the characteristic undercooling degree.Furthermore,the addition of Co and the reduction of Cu not only result in a lower solidification rate of the alloy,but also contribute to the homogenisation of the grain size. 展开更多
关键词 non-equilibrium solidification recalescence effect solidification character microstructure
原文传递
Effects of Hydrogen on the Methane Coupling under Non-equilibrium Plasma
10
作者 代斌 张秀玲 +1 位作者 宫为民 何仁 《Plasma Science and Technology》 SCIE EI CAS CSCD 2001年第1期637-639,共3页
In this paper, hydrogen is first utilized in the study on methane coupling under nonequilibrium plasma. Results indicate that the addition of hydrogen is beneficial. to the methane coupling so as to increase the conv... In this paper, hydrogen is first utilized in the study on methane coupling under nonequilibrium plasma. Results indicate that the addition of hydrogen is beneficial. to the methane coupling so as to increase the conversion rate of methane and the yield of C2 hydrocarbon with a gradual increase in the addition of hydrogen in a certain range of proportionality. This conclusion explores a new route of hydrogenated methane coupling. 展开更多
关键词 effects of Hydrogen on the Methane Coupling under non-equilibrium Plasma
在线阅读 下载PDF
Effects of Anisotropy on Scalar Field Ghost Dark Energy and the Non-Equilibrium Thermodynamics in Fractal Cosmology
11
作者 A.Najafi H.Hossienkhani 《Communications in Theoretical Physics》 SCIE CAS CSCD 2017年第10期553-564,共12页
Since the fractal cosmology has been created in early universe, therefore their models were mostly isotropic. The majority of previous studies had been based on FRW universe, while in the early universe, the best mode... Since the fractal cosmology has been created in early universe, therefore their models were mostly isotropic. The majority of previous studies had been based on FRW universe, while in the early universe, the best model for describing fractal cosmology is actually the anisotropic universe. Therefore in this work, by assuming the anisotropic universe, the cosmological implications of ghost and generalized ghost dark energy models with dark matter in fractal cosmology has been discussed. Moreover, the different kinds of dark energy models such as quintessence and tachyon field, with the generalized ghost dark energy in fractal universe has been investigated. In addition, we have reconstructed the Hubble parameter, H, the energy density, p, the deceleration parameter, q, the equations of state parameter, wD, for both ghost and generalized ghost dark energy models. This correspondence allows us to reconstruct the potential and the dynamics of a fractal canonical scalar field according to the evolution of generalized ghost dark energy density. Eventually, thermodynamics of the cosmological apparent horizon in fractal cosmology was investigated and the validity of the Generalized second law of thermodynamics (GSLT) have been examined in an anisotropic universe. The results show the influence of the anisotropy on the OSLT of thermodynamics in a fractal cosmology. 展开更多
关键词 anisotropic universe fractal cosmology ghost DE generalized ghost DE non-equilibrium ther-modynamics generalized second law
原文传递
Dynamic process of trace boron non-equilibrium grain boundary segregation and the effect of cooling rate
12
作者 PingWu XinlaiHe +1 位作者 BingCao SenChen 《Journal of University of Science and Technology Beijing》 CSCD 2003年第3期30-34,共5页
The dynamic process of non-equilibrium grain boundary segregation of traceboron in Fe-40 percent Ni alloy during cooling and the effect of cooling rate were investigated byboron tracking autoradiography technique. The... The dynamic process of non-equilibrium grain boundary segregation of traceboron in Fe-40 percent Ni alloy during cooling and the effect of cooling rate were investigated byboron tracking autoradiography technique. The results indicate that during cooling process, theamount of segregated boron on grain boundary firstly increases fast, then enters a comparativelyeven increasing stage and increases rapidly again at the third stage. The details of each stagevaried with cooling rate are explained. When the segregation develops to a certain degree, thesegregated boron atoms transform from solute status to precipitate status. 展开更多
关键词 BORON grain boundary non-equilibrium segregation dynamic process
在线阅读 下载PDF
Novel Methodologies for Preventing Crack Propagation in Steel Gas Pipelines Considering the Temperature Effect 被引量:3
13
作者 Nurlan Zhangabay Ulzhan Ibraimova +4 位作者 Marco Bonopera Ulanbator Suleimenov Konstantin Avramov Maryna Chernobryvko Aigerim Yessengali 《Structural Durability & Health Monitoring》 EI 2025年第1期1-23,共23页
Using the software ANSYS-19.2/Explicit Dynamics,this study performedfinite-element modeling of the large-diameter steel pipeline cross-section for the Beineu-Bozoy-Shymkent gas pipeline with a non-through straight crac... Using the software ANSYS-19.2/Explicit Dynamics,this study performedfinite-element modeling of the large-diameter steel pipeline cross-section for the Beineu-Bozoy-Shymkent gas pipeline with a non-through straight crack,strengthened by steel wire wrapping.The effects of the thread tensile force of the steel winding in the form of single rings at the crack edges and the wires with different winding diameters and pitches were also studied.The results showed that the strengthening was preferably executed at a minimum value of the thread tensile force,which was 6.4%more effective than that at its maximum value.The analysis of the influence of the winding dia-meters showed that the equivalent stresses increased by 32%from the beginning of the crack growth until the wire broke.The increment in winding diameter decelerated the disclosure of the edge crack and reduced its length by 8.2%.The analysis of the influence of the winding pitch showed that decreasing the distance between the winding turns also led to a 33.6%reduction in the length of the straight crack and a 7.9%reduction in the maximum stres-ses on the strengthened pipeline cross-section.The analysis of the temperature effect on the pipeline material,within a range from-40℃to+50℃,resulted in a crack length change of up to 5.8%.As the temperature dropped,the crack length decreased.Within such a temperature range,the maximum stresses were observed along the cen-tral area of the crack,which were equal to 413 MPa at+50℃and 440 MPa at-40℃.The results also showed that the presence of the steel winding in the pipeline significantly reduced the length of crack propagation up to 8.4 times,depending on the temperature effect and design parameters of prestressing.This work integrated the existing methods for crack localization along steel gas pipelines. 展开更多
关键词 Crack propagation finite-element internal pressure PRESTRESSING steel gas pipeline temperature effect
在线阅读 下载PDF
The Effect of Discharge Power on the Atmospheric Pressure Non-equilibrium Ar/O_2/TiCl_4 Plasma Deposition of TiO_2 Film
14
作者 王德信 杨沁玉 +2 位作者 郭颖 丁可 张菁 《Journal of Donghua University(English Edition)》 EI CAS 2012年第5期389-392,共4页
Deposition of TiO2 film from atmospheric pressure non- equilibrium Ar/O2/TiCl4 plasma was done to study the effect of discharge power during the film deposition process in this paper. TiO2 films with kinds of morpholo... Deposition of TiO2 film from atmospheric pressure non- equilibrium Ar/O2/TiCl4 plasma was done to study the effect of discharge power during the film deposition process in this paper. TiO2 films with kinds of morphologies and controlled crystallization were deposited from mixtures of TiCl4 and O2 on quartz substrate by one step process. Scanning electron microscope (SEM) and transmission electron microscope (TEM) were used to analyze the morphology and crystallization of the deposited TiO2 films. It was found that the discharge power played a key role in the morphology and crystallization of the deposited TiO2 film whether the flow of TiCl4was large or small. When the flow of TiCl4 was large, the deposited TiO2 film was amorphous particles at low discharge power and was multi-crystalline at high discharge power. When the flow of TiCl4 was small, the deposited TiO2 film became more compact and the crystallization was enhanced as the discharge power increased. The dependence of the discharge current and the applied voltage with the discharge power indicated that it was a glow discharge. The gas temperature which increases with the discharge power is one of the main causes that affect the morphology and crystallization of the deposited film. 展开更多
关键词 atmospheric pressure non-equilibrium Ar/ O2/ TiCl4 plasma TiO2 discharge power
在线阅读 下载PDF
Microstructural evolution during the progressive transformation-induced plasticity effect in a Fe-0.1C-5Mnmedium manganese steel 被引量:1
15
作者 Mei Zhang Wenhao Li +3 位作者 Yangfei Chen Yang Jiang Xiaofei Guo Han Dong 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS 2025年第2期369-379,共11页
The microstructural evolution of a cold-rolled and intercritical annealed medium-Mn steel(Fe-0.10C-5Mn)was investigated during uniaxial tensile testing.In-situ observations under scanning electron microscopy,transmiss... The microstructural evolution of a cold-rolled and intercritical annealed medium-Mn steel(Fe-0.10C-5Mn)was investigated during uniaxial tensile testing.In-situ observations under scanning electron microscopy,transmission electron microscopy,and X-ray diffraction analysis were conducted to characterize the progressive transformation-induced plasticity process and associated fracture initiation mechanisms.These findings were discussed with the local strain measurements via digital image correlation.The results indicated that Lüders band formation in the steel was limited to 1.5%strain,which was mainly due to the early-stage martensitic phase transformation of a very small amount of the less stable large-sized retained austenite(RA),which led to localized stress concentrations and strain hardening and further retardation of yielding.The small-sized RA exhibited high stability and progressively transformed into martensite and contributed to a stably extended Portevin-Le Chatelier effect.The volume fraction of RA gradually decreased from 26.8%to 8.2%prior to fracture.In the late deformation stage,fracture initiation primarily occurred at the austenite/martensite and ferrite/martensite interfaces and the ferrite phase. 展开更多
关键词 medium-Mn steel retained austenite progressive transformation-induced plasticity effect local strain fracture initiation
在线阅读 下载PDF
Luteolin and glycyrrhetinic exert cooperative effect on liver cancer by selfassembling into carrier-free nanostructures 被引量:3
16
作者 Lanlan Zong Yuxin Dai +6 位作者 Jiahao Xu Chaofeng Qiao Yao Qi Chengyuan Ma Hong Li Xiaobin Pang Xiaohui Pu 《Chinese Chemical Letters》 2025年第10期447-452,共6页
Liver cancer is the fourth cause of cancer-related deaths and the primary cause of death in patients with compensated cirrhosis.In recent years,the role of traditional Chinese medicine in the treatment of liver cancer... Liver cancer is the fourth cause of cancer-related deaths and the primary cause of death in patients with compensated cirrhosis.In recent years,the role of traditional Chinese medicine in the treatment of liver cancer has attracted more and more attention and recognition.Luteolin(LUT)and glycyrrhetinic(GA)are natural compounds extracted from Chinese herbal medicine.LUT exhibits various biological activity including anti-inflammatory,antibacterial,antiviral,anti-tumor,and neuroprotective effects.GA significantly inhibits the growth and metastasis of cancer cells.However,the low water solubility of both compounds hinders their clinical applications.In this study,rod-shaped nanoparticles(NPs)self-assembled from LUT and GA were designed to enhance drug solubility and tumor-targeting capability.We verified that the assembly mechanism of the NPs was π-π stacking.These NPs significantly inhibited the proliferation of liver cancer cells while had no significant effect on normal liver cells.In a mouse model of liver cancer,these NPs demonstrated superior tumor-targeting ability due to the enhanced permeability and retention effect,and the affinity of GA for liver cancer cells,resulting in better therapeutic efficacy with lower systemic toxicity.Results of network pharmacology analysis showed that LUT and GA respectively targeted estrogen receptor 1(ESR1)protein and cyclin-dependent kinase 1(CDK1)protein to corporately induce tumor cell cycle arrest,which induced the inhibition of tumor cell proliferation.In conclusion,this study provides a novel reference for the treatment of liver cancer. 展开更多
关键词 LUTEOLIN Glycyrrhetinic Nanoself-assembly Synergistic effect Liver cancer
原文传递
(N-Z) Odd-Even Effect for the Non-Equilibrium Mechanism of (p, n) Reactions
17
作者 Nikolay V. Komilov 《Journal of Physical Science and Application》 2014年第3期166-176,共11页
The neutron spectra and angular distributions from (p,n) reactions in the input proton energy range 6-25 MeV were analyzed. These are the old experimental data, however, re-analysis of these data reveals very intere... The neutron spectra and angular distributions from (p,n) reactions in the input proton energy range 6-25 MeV were analyzed. These are the old experimental data, however, re-analysis of these data reveals very interesting peculiarities which never have been discussed before. The high energetic part of neutron spectrum due to the direct mechanism changes considerably from one isotope to other. This difference was described with incorporation of two components which provide the "broad bump", or "step like" shape of neutron spectra at high energy. The properties of these components are: different shape, energy shift between them, and very strong fluctuation between different isotopes for ratio of cross sections connected with partial contribution. One may conclude that shape of non-compound neutron spectrum demonstrates very strong (N-Z) odd-even effect. The direct comparison of experimental data, and semi-empirical results with (p,n) spectra predicted by the EMPIRE code, gave evidence that the traditional approach cannot predict this effect. New finding may explain the "constant temperature" dependence for level density in mass range A-60 discussed in several investigations. These new experimental peculiarities were demonstrated, and it may be considered as reality. At the same time there is not consequent physical model for their explanation. The fact that spectrum shape is correlated with N-Z value may give a hint that discussed effects are connected with "halo-neutrons". 展开更多
关键词 Nuclear reactions neutron emission direct mechanism odd-even effect.
在线阅读 下载PDF
Progress in Flexoelectric Effect Research and Related Applications 被引量:1
18
作者 Pengwen Guo Mengmeng Jia +3 位作者 Di Guo Tianling Ren Zhong Lin Wang Junyi Zhai 《SmartSys》 2025年第1期39-46,共8页
The flexoelectric effect refers to the electromechanical coupling between electric polarization and mechanical strain gradient.It universally exists in a variety of materials in any space group,such as liquid crystals... The flexoelectric effect refers to the electromechanical coupling between electric polarization and mechanical strain gradient.It universally exists in a variety of materials in any space group,such as liquid crystals,dielectrics,biological materials,and semiconductors.Because of its unique size effect,nanoscale flexoelectricity has shown novel phenomena and promising applications in electronics,optronics,mechatronics,and photovoltaics.In this review,we provide a succinct report on the discovery and development of the flexoelectric effect,focusing on flexoelectric materials and related applications.Finally,we discuss recent flexoelectric research progress and still‐unsolved problems. 展开更多
关键词 electric polarization flexoelectric effect flexotronics size effect strain gradient
在线阅读 下载PDF
Does the housing provident fund cause housing inequality?The micromechanism and macroeffect in China 被引量:1
19
作者 Anquan Zhang Lu Liu 《Financial Innovation》 2025年第1期3037-3064,共28页
This study explores the housing distribution effect of the Housing Provident Fund(HPF)system on households.Utilizing data from the China Household Finance Survey conducted in 2013,2015,2017,and 2019,this study empiric... This study explores the housing distribution effect of the Housing Provident Fund(HPF)system on households.Utilizing data from the China Household Finance Survey conducted in 2013,2015,2017,and 2019,this study empirically investigates this effect from two dimensions:the impact of HPF payments on household income and housing loan behavior,and the impact on the Gini coefficient of housing assets within the group.The results indicate that the HPF payment does not significantly impact household income levels.Instead,it increases their likelihood of obtaining housing loans,particularly for middle-income households.Additionally,for any group of families,the HPF payment decreased the housing Gini coefficient among households by approximately 0.11 units.This study may be the first to provide the most direct empirical evidence on the extent of HPF’s impact on housing inequality within a group.It also questions the inference in the literature that“HPF will aggravate housing inequality within the group.”Based on this study’s findings,we expect that housing inequality will continue to be alleviated with continued HPF implementation.In particular,this effect will be more significant if the credit support for lowincome families to purchase houses through the HPF can be further enhanced. 展开更多
关键词 Housing provident fund(HPF) Income effect Credit effect Housing inequality CHFS
在线阅读 下载PDF
Effects of Fruit-Crop Agroforestry Systems on Pest and Natural Enemy Diversity 被引量:1
20
作者 LI Guoyu LIU Tingting +3 位作者 WEI Wenwen ZHANG Shuai LI Zhe ZHANG Wei 《绿洲农业科学与工程》 2025年第1期80-91,共12页
Agricultural intensification has led to an increase in monoculture and the use of chemical pesticides,resulting in a decline in biodiversity and a reduction in ecosystem services,particularly biological pest managemen... Agricultural intensification has led to an increase in monoculture and the use of chemical pesticides,resulting in a decline in biodiversity and a reduction in ecosystem services,particularly biological pest management.However,studies have shown that agroforestry can not only improve land productivity and biodiversity but also regulate some ecosystem services.This study reviews the impacts of physical and biological factors on herbivorous pests,parasites,and predatory natural enemies in fruit-crop agroforestry systems.Fruit-crop agroforestry systems provide high spatial heterogeneity by altering crop layouts,regulating the microclimate and soil quality,and offering food resources and shelter for natural enemies,thus promoting biological pest control.This enhances biological control and makes the agrocomplex system an effective tool for sustainable agriculture.Our research shows that volatile plant substances attract or repel pests and natural enemies based on the characteristics of the insects themselves.When scientifically designed,fruit-crop agroforestry systems provide high spatial heterogeneity and favorable microclimatic conditions,which enhance biological pest control and make the agroforestry system an effective tool for sustainable agriculture.Our research shows that fruit-crop agroforestry systems can provide richer food resources and habitat,enhancing biological pest control and improving pest management. 展开更多
关键词 AGROFORESTRY PEST natural enemy BIODIVERSITY effect factors
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部