Intracellular transports of cargoes are performed by biological molecular motors that move processively along their linear tracks.In some cases,the cargo can interact with the track.A typical example of these cases is...Intracellular transports of cargoes are performed by biological molecular motors that move processively along their linear tracks.In some cases,the cargo can interact with the track.A typical example of these cases is the transport of a major mitotic signaling module,the chromosomal passenger complex(CPC),along the microtubule toward the equatorial cortex by a kinesin-6 motor during anaphase,where the CPC can interact with the microtubule.Here,an analytical theory is presented on the dynamics of the molecular motor transporting a track-interacted cargo.The theory is then applied to the transport of the track-interacted cargo by kinesin-6 and by kinesin-1 motors,with the theoretical results reproducing quantitatively the available experimental data.It is found that a diffusive cargo along the track,with the diffusion constant≥0.1μm2s-1,can largely enhance the processivity relative to the non-diffusive cargo and relative to the cargo having no interaction with the track.展开更多
This paper proposes a novel cargo loading algorithm applicable to automated conveyor-type loading systems.The algorithm offers improvements in computational efficiency and robustness by utilizing the concept of discre...This paper proposes a novel cargo loading algorithm applicable to automated conveyor-type loading systems.The algorithm offers improvements in computational efficiency and robustness by utilizing the concept of discrete derivatives and introducing logistics-related constraints.Optional consideration of the rotation of the cargoes was made to further enhance the optimality of the solutions,if possible to be physically implemented.Evaluation metrics were developed for accurate evaluation and enhancement of the algorithm’s ability to efficiently utilize the loading space and provide a high level of dynamic stability.Experimental results demonstrate the extensive robustness of the proposed algorithm to the diversity of cargoes present in Business-to-Consumer environments.This study contributes practical advancements in both cargo loading optimization and automation of the logistics industry,with potential applications in last-mile delivery services,warehousing,and supply chain management.展开更多
目的针对飞机货舱配载方案评估中多属性决策的复杂性,以及现有评估方法在权重确定上过度依赖专家经验导致的主观偏差,或单纯依赖客观数据忽略决策者偏好的局限性,提出一种融合主观先验与客观数据驱动的混合赋权评估模型,以提供更为合理...目的针对飞机货舱配载方案评估中多属性决策的复杂性,以及现有评估方法在权重确定上过度依赖专家经验导致的主观偏差,或单纯依赖客观数据忽略决策者偏好的局限性,提出一种融合主观先验与客观数据驱动的混合赋权评估模型,以提供更为合理、可靠的配载方案择优决策支持。方法首先,引入大型语言模型(Large language model,LLM),构建“虚拟专家委员会”,通过精心设计的提示词工程,获取多维度、多情境下的主观权重。其次,针对传统熵权法对数据分布敏感、难以有效区分指标优劣等问题,提出一种改进的数据预处理熵权法(Improved data preprocessing entropy weighting method,IDPEW),该方法结合指标值的辨识度和信息熵的均衡性来确定客观权重。最后,将LLM生成的主观权重与IDPEW计算的客观权重进行加权组合,构建综合评价函数,对飞机货舱配载方案进行全面评估和排序。结果实验结果表明,LLM模拟专家意见时最关注“装载率”(主观权重0.2250),而IDPEW方法从数据中识别出“横向不平衡度”最具区分力(客观权重0.2481)。混合赋权模型(α=0.5)有效平衡了主客观偏好,在24个方案中精准识别出综合性能最优的方案,验证了模型在复杂情境下的稳定性。结论创新性地利用LLM低成本构建“虚拟专家”获取先验知识,并通过耦合指标辨识度与均衡性的IDPEW方法,提升了客观赋权精度。该模型克服了单一赋权的局限,为飞机货舱配载方案的科学评估提供了一种兼具可解释性和实用性的新范式。展开更多
Cargo airdrop has long been one of the most important measures to deal with urgent immediate needs, such as providing as- sists in military operations and sending relief to disaster areas, just to name a few. Because ...Cargo airdrop has long been one of the most important measures to deal with urgent immediate needs, such as providing as- sists in military operations and sending relief to disaster areas, just to name a few. Because it is carried out during flight, it is necessary to investigate the influences of the drop process on flight characteristics to ensure successful execution of the task. This article mainly studies the modeling of flight systems in large flying transport planes with cargo moving in it. By buildi...展开更多
基于角色的协同RBC(Role-Based Collaboration)是一套研究角色及它们之间复杂关系的方法、理论和技术。在RBC中,群组角色分配GRA(Group Role Assignment)既是一个关键问题,也是一个难题。已有许多研究探讨了基于Q(Qualification)矩阵来...基于角色的协同RBC(Role-Based Collaboration)是一套研究角色及它们之间复杂关系的方法、理论和技术。在RBC中,群组角色分配GRA(Group Role Assignment)既是一个关键问题,也是一个难题。已有许多研究探讨了基于Q(Qualification)矩阵来处理GRA问题,但仅利用Q矩阵难以描述问题中的复杂约束关系。因此,将约束集(Constraint)引进E-CARGO模型,提出了带约束的EC-CARGO模型,研究了RBC、GRA、SAT(SATisfaction)和CSP(Constraint Satisfaction Problem)之间的联系,建立了RBC-GRA-SAT-CSP问题求解转换关系;提出应用EC-CARGO模型求解经典CSP约束满足问题的方法,进而描述了应用GRA求解CSP约束满足问题的通用框架。最后以N皇后问题为例,验证了通过GRA的约束指派求解CSP问题的有效性。展开更多
基金supported by the Youth Project of Science and Technology Research Program of Chongqing Education Commission of China(No.KJQN202404522)。
文摘Intracellular transports of cargoes are performed by biological molecular motors that move processively along their linear tracks.In some cases,the cargo can interact with the track.A typical example of these cases is the transport of a major mitotic signaling module,the chromosomal passenger complex(CPC),along the microtubule toward the equatorial cortex by a kinesin-6 motor during anaphase,where the CPC can interact with the microtubule.Here,an analytical theory is presented on the dynamics of the molecular motor transporting a track-interacted cargo.The theory is then applied to the transport of the track-interacted cargo by kinesin-6 and by kinesin-1 motors,with the theoretical results reproducing quantitatively the available experimental data.It is found that a diffusive cargo along the track,with the diffusion constant≥0.1μm2s-1,can largely enhance the processivity relative to the non-diffusive cargo and relative to the cargo having no interaction with the track.
基金supported by the BK21 FOUR funded by the Ministry of Education of Korea and National Research Foundation of Korea,a Korea Agency for Infrastructure Technology Advancement(KAIA)grant funded by the Ministry of Land,Infrastructure,and Transport(Grant 1615013176)IITP(Institute of Information&Coummunications Technology Planning&Evaluation)-ICAN(ICT Challenge and Advanced Network of HRD)grant funded by the Korea government(Ministry of Science and ICT)(RS-2024-00438411).
文摘This paper proposes a novel cargo loading algorithm applicable to automated conveyor-type loading systems.The algorithm offers improvements in computational efficiency and robustness by utilizing the concept of discrete derivatives and introducing logistics-related constraints.Optional consideration of the rotation of the cargoes was made to further enhance the optimality of the solutions,if possible to be physically implemented.Evaluation metrics were developed for accurate evaluation and enhancement of the algorithm’s ability to efficiently utilize the loading space and provide a high level of dynamic stability.Experimental results demonstrate the extensive robustness of the proposed algorithm to the diversity of cargoes present in Business-to-Consumer environments.This study contributes practical advancements in both cargo loading optimization and automation of the logistics industry,with potential applications in last-mile delivery services,warehousing,and supply chain management.
文摘目的针对飞机货舱配载方案评估中多属性决策的复杂性,以及现有评估方法在权重确定上过度依赖专家经验导致的主观偏差,或单纯依赖客观数据忽略决策者偏好的局限性,提出一种融合主观先验与客观数据驱动的混合赋权评估模型,以提供更为合理、可靠的配载方案择优决策支持。方法首先,引入大型语言模型(Large language model,LLM),构建“虚拟专家委员会”,通过精心设计的提示词工程,获取多维度、多情境下的主观权重。其次,针对传统熵权法对数据分布敏感、难以有效区分指标优劣等问题,提出一种改进的数据预处理熵权法(Improved data preprocessing entropy weighting method,IDPEW),该方法结合指标值的辨识度和信息熵的均衡性来确定客观权重。最后,将LLM生成的主观权重与IDPEW计算的客观权重进行加权组合,构建综合评价函数,对飞机货舱配载方案进行全面评估和排序。结果实验结果表明,LLM模拟专家意见时最关注“装载率”(主观权重0.2250),而IDPEW方法从数据中识别出“横向不平衡度”最具区分力(客观权重0.2481)。混合赋权模型(α=0.5)有效平衡了主客观偏好,在24个方案中精准识别出综合性能最优的方案,验证了模型在复杂情境下的稳定性。结论创新性地利用LLM低成本构建“虚拟专家”获取先验知识,并通过耦合指标辨识度与均衡性的IDPEW方法,提升了客观赋权精度。该模型克服了单一赋权的局限,为飞机货舱配载方案的科学评估提供了一种兼具可解释性和实用性的新范式。
基金National Natural Science Foundation of China (60134010)Aeronautical Science Foundation of China (2007ZD53053)
文摘Cargo airdrop has long been one of the most important measures to deal with urgent immediate needs, such as providing as- sists in military operations and sending relief to disaster areas, just to name a few. Because it is carried out during flight, it is necessary to investigate the influences of the drop process on flight characteristics to ensure successful execution of the task. This article mainly studies the modeling of flight systems in large flying transport planes with cargo moving in it. By buildi...
