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Breast Cancer: Epidemiological, Clinical, and Therapeutic Aspects in Pointe Noire (Congo Brazzaville) 被引量:1
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作者 C. F. S. Ngatali A. F. Bolenga Liboko +5 位作者 E. Ndounga Y. Mabila D. Moukassa J. B. Nkoua-Mbon P. E. G. Sounga Bandzouzi L. M. A. Boumba 《Open Journal of Pathology》 2019年第4期76-85,共10页
Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. The objective of our study was to describe the epidemiological, clinical and therapeutic aspects of breast ca... Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. The objective of our study was to describe the epidemiological, clinical and therapeutic aspects of breast cancer at the General Hospital of Loandjili in Pointe Noire. Patients and Methods: This was a descriptive and cross-sectional study that took place in the Cancer Department of the General Hospital of Loandjili in Pointe Noire during the period from January 1st, 2012 to December 31st, 2016 for duration of 5 years. 54 records of patients over 18 years of age with histological evidence were collected. The variables studied were: age, level of education, time to presentation, telltale sign, stage of extension, histological type, and histological grade. Chi-square test was used to compare variables and groups. Results: At the end of this study, we collected 54 files of breast cancer patients from 150 patients hospitalized in the Cancer Department. The frequency of breast cancer was 36%. The average age was 50 ± 13.6 years;the extremes were 27 years and 79 years. The most represented age group was from 37 to 40 years old with a percentage of 28%. The patient’s level of study was primary in the majority of cases (57%). The most represented histological type was invasive ductal carcinoma, (100%). The majority of patients arrived at advanced stages 44.4% and metastatic stages 26%. Patients were treated in most of cases by chemotherapy (82%), surgery (42%) and radiotherapy (10%). There was a correlation between time of presentation and stage of extension. Conclusion: Breast cancer is the first cancer of the woman in Pointe Noire. Patients arrive at advanced stages;the most common histological type is invasive ductal carcinoma. The presentation time is correlated with the extension stage. These results suggest the establishment of a cancer control program in developing countries. 展开更多
关键词 EPIDEMIOLOGICAL CLINICAL Therapeutic Breast Cancer Pointe noire
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Epidemiological Clinical and Histological Aspects of Gynecological and Breast Cancer in Pointe Noire (Congo Brazzaville)
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作者 Christian F. S. Ngatali A. Bolenga Liboko +2 位作者 Y. Mabiala D. Moukassa J. B. Nkoua-Mbon 《Advances in Breast Cancer Research》 2022年第2期89-100,共12页
INTRODUCTION: The objective of our study was to determine the epidemiological clinical and histological aspects of gynecological and breast cancers in Pointe-Noire. PATIENTS AND METHODS: This was a retrospective descr... INTRODUCTION: The objective of our study was to determine the epidemiological clinical and histological aspects of gynecological and breast cancers in Pointe-Noire. PATIENTS AND METHODS: This was a retrospective descriptive study that took place in the cancerology and internal medicine department during the period from January 1, 2012 to December 31, 2021, i.e. a period of 10 years. Women with histological diagnosis of gynecological and breast cancers were included in our study. The variables studied were: frequency, age, alcohol and tobacco consumption, histological type, stage of extension, location of cancer. Bivariate analysis was done between age and location of the tumour. The statistical test used was the KHI2 test. The results were statistically significant for a value of p RESULTS: We collected 400 files from women with cancer. Among the 400 files, 265 were represented by gynecological and breast cancers, that is a frequency of 65.43%. Among the 265 cases of gynecological and breast cancer identified during this study period, breast cancer represented the first rank with 52% frequency. Cervical cancer accounted for 41% followed by ovarian cancer (5%) and endometrial (2%). Cancer of vulva was represented by a single case. The average age of patients with gynecological and breast cancers during our study was 52 ± 12 years. The average age of patients with cancer of the breast, cervix, ovarian, endometrial was respectively 49 ± 11.97 years, 54.73 ± 12.91 years old, 50 ± 14 years, 67 ± 14.24 years, the age of the vulva cancer patient was 51 years old. The histological type of breast cancer was represented by infiltrating ductal adenocarcinoma in 91% of cases, invasive lobular carcinoma in 7% and sarcoma in 2%. Cervical cancers were represented by squamous cell carcinomas in 95% of cases and adenocarcinomas in 5% of cases. Vulva cancer was represented by squamous cell carcinoma, ovarian cancer was represented by epithelial tumors (adenocarcinoma) in 100% of cases. Endometrial cancers were represented by endometrial adenocarcinoma. All cancers were diagnosed at advanced stages (locoregional and metastatic stage). Patients over the age of 50 had more gynecological and breast cancers;but this result was not significant. CONCLUSION: Gynecological and breast cancers are frequent and constitute the first cancer of Congolese women in Pointe-Noire. Breast cancer is the first cancer followed by cancer of the cervix and ovaries. The histological types are those of the literature. Patients with gynecological and breast cancers consult at very advanced stages. 展开更多
关键词 GYNECOLOGICAL Breast Cancer EPIDEMIOLOGICAL CLINICAL HISTOLOGICAL Aspects Pointe noire Congo Brazzaville
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Metastatic Breast Cancer Survival in Pointe Noire: Analysis of 30 Cases
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作者 C. F. S. Ngatali A. F. Bolenga Liboko +6 位作者 M. L. Eouani L. M. A. Boumba P. E. G. Sounga Bandzouzi E. Ndounga Y. Mabila D. Moukassa J. B. Nkoua-Mbon 《Open Journal of Pathology》 2019年第4期86-99,共14页
Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. About 5% to 10% of breast cancer patients present with metastases. While the 5-year survival of patients with... Introduction: Breast cancer is the leading cancer and the leading cause of cancer death in women worldwide. About 5% to 10% of breast cancer patients present with metastases. While the 5-year survival of patients with local breast cancer varies around 98.8%, this survival rate drops to around 26.3% for metastatic patients. The objective of this study was to determine the survival of patients with metastatic breast cancer in resource-limited settings. Patients and Methods: This was a cross-sectional descriptive study that took place in the Cancer Department of the General Hospital of Loandjili in Pointe Noire during the period from January 1, 2013 to December 31, 2018, for duration of 6 years. 30 records of patients over 18 years of age and with histological evidence who received at least 3 courses of chemotherapy were collected. The variables studied were: age, level of education, socio-economic level, menopausal status, history, WHO status, menopausal status, tumor size, histological type, tumor location, the type of treatment and survival. Survival was calculated by Kaplan Meier method. Fisher’s exact test was used to search for correlation between variables. Results: The average age was 52.62 ± 10.96 years old. The extremes were 33 years and 75 years old. The most represented level of education was the primary level in 67% of cases. The majority of patients had low socioeconomic status in 50% of cases. The patients were menopausal in 57% of cases. The antecedents of cancer were present in 13% of cases. 50% of patients had a WHO status performance at 2. The tumor size was greater than 2 cm in 77% of cases. The most represented histological type was invasive ductal carcinoma in 93% of cases. The most represented histological grade was Scharff grade III Richardson bloom in 80% of cases. The most represented metastatic localization was pulmonary in 33% of cases. The metastatic localizations were unique in 47% of cases and multiple in 53% of cases. Anthracycline-based chemotherapy was more used in 53% of cases. Bivariate analysis revealed a correlation between tumor size and number of metastases, p 0.05. Patients treated with anthracyclines were greater than that of patients treated with taxanes in combination was 26.48 months, p > 0.05. Conclusion: Metastatic breast cancer remains an incurable disease, its survival remains low despite diagnostic and therapeutic advances that remain difficult to access for our resource-poor developing countries. Patients are treated with conventional chemotherapy (anthracyclines and taxanes). The most common metastases are respectively pulmonary, hepatic and cerebral in our context. 展开更多
关键词 BREAST CANCER METASTATIC SURVIVAL Pointe noire CONGO
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《白日焰火》:黑色电影类型的最新尝试 被引量:2
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作者 吕争 《电影文学》 北大核心 2015年第5期72-74,78,共4页
2014年金熊奖获奖影片《白日焰火》应该说代表着华语电影近年在世界范围内的较高成就。本文把《白日焰火》放在黑色电影发展史的背景下考察,试图厘清黑色电影类型的基本意义范畴,指出其形式和内涵的复杂性,指出该片在类型和风格上作为... 2014年金熊奖获奖影片《白日焰火》应该说代表着华语电影近年在世界范围内的较高成就。本文把《白日焰火》放在黑色电影发展史的背景下考察,试图厘清黑色电影类型的基本意义范畴,指出其形式和内涵的复杂性,指出该片在类型和风格上作为黑色电影的典型性,进而分别从冷硬侦探、蛇蝎美女的形象塑造方面讨论了该片对黑色电影传统模式的颠覆,并分析了该片在我国本土现代性空间的挖掘。 展开更多
关键词 白日焰火 黑色电影(Film Noir) 现代性空间
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Papulosa Nigra Dermatosis Another Factor Associated with Cardio-Vascular Diseases?
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作者 Solange Flore Ngamami Mongo Bani Aloise Macaire +3 位作者 Franck Yannis Kouikani Kivié Mou-Moué Ngolo Letomo Bayonne S. E. Kombo Bertrand Fikahem Ellenga Mbolla 《World Journal of Cardiovascular Diseases》 2023年第12期819-826,共8页
Objectives: To determine the correlation between dermatosis papulosa nigra (DPN) and cardiovascular disease (CVD). Patients and Method: A retrospective study was conducted between April 2022 and March 2023 in cardiolo... Objectives: To determine the correlation between dermatosis papulosa nigra (DPN) and cardiovascular disease (CVD). Patients and Method: A retrospective study was conducted between April 2022 and March 2023 in cardiology at Loandjili General Hospital. Were included all adult patients older than 18 years of age presenting with DPN, and divided into two groups according to the presence of CVD. Hypertension (HT), endomyocardial fibrosis, dilated and restrictive cardiomyopathy, chronic pulmonary heart, ischemic heart disease, stroke, and valvular heart disease were retained as CVD. Pregnant women, Peutz Jeghers syndrome and all dermatosis with cardiovascular manifestations were excluded. Studied variables were clinico-demographic, hereditary and behavioral. Results: A total of 55 patients were selected. There were 40 patients with CVD, 15 patients without CVD, 43 women (78.1%) and 12 men (21.8%). Mean age was 52 ± 12.6 years (extremes: 22 - 85 years). There was a significant difference between age and sex (P 0.05). There were 34 hypertensive patients, 10 patients with diabetes mellitus, 7 strokes, 2 endomyocardial fibrosis and 2 ischemic heart diseases. Periorbital location was representative was frequently found in the group with CVD. Hereditary and behavioral factors were involved in the development of DPN and CVD. There was a significant correlation between DPN and onset in childhood (P 0.05), between hypertension and use of medication (P 0.05), and between onset in childhood (P 0.05) and use of mercury containing soap (P 0.05). Conclusion: DPN predominates in young women. The occurrence of CVD depends on DPN location. Hereditary and behavioral factors associated with development of DPN are CVD factor risks. 展开更多
关键词 Papulosa Nigra Cardiovascular Disease CORRELATION Pointe noire
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Rooting Abilities in <i>Vitis vinifera</i>L.: Total Lipid and Fatty Acids Evolution in Perle Noir Cutting
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作者 Henda Cheikhrouhou Manel Zrida Bechir Ezzili 《Agricultural Sciences》 2015年第5期498-504,共7页
Rooting ability in Vitis vinifera L. is the phenomena studied. The evolution of the total lipids contents and fatty acids amount of cuttings during the rooting were determined. Total lipid extraction was carried out b... Rooting ability in Vitis vinifera L. is the phenomena studied. The evolution of the total lipids contents and fatty acids amount of cuttings during the rooting were determined. Total lipid extraction was carried out by an extraction solvent consisting of a mixture of chloroform and methanol. Methylation of fatty acids was carried out by the boron trifluoride methanol complex. Their analysis is performed by gas chromatography. We have obtained a content of merithallus lipids equivalent with then in bibliography. In other hand 3 fatty acids were obtained: eicosapentaenoic acid, oleic acid and docosanoic acid. Among the studied of rooting abilities, we observed decreased levels of total lipids and in the essential fatty acids: eicosapentaenoic acid C20:5 n-3 and oleic acid C18:1 n-9. Minor fatty acids cuttings experimental have a variable evolution. Lipids and certain fatty acids may be markers of rooting in the vine. 展开更多
关键词 Lipids CUTTING Fatty Acids ROOTING Perle Noir VITIS VINIFERA L.
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The Dark Side of the Screen—A Resistance to Changing Times
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作者 Maria Antónia Lima 《Journal of Literature and Art Studies》 2020年第9期829-834,共6页
This essay argues that black and white cinema spawned a resistance to changing times that is still very present in the new generation of directors who follow classic film traditions while subverting them with consiste... This essay argues that black and white cinema spawned a resistance to changing times that is still very present in the new generation of directors who follow classic film traditions while subverting them with consistent narrative inventions.The Artist,the best picture Oscar award winner in 2012,is an example of this resistance as it pays homage to some of the greatest silent films of the first two or three decades of cinema history.“The Dark Side of the Screen”aims to underline that there is an unchanging power of the phantasmagoria so present in black and white movies,produced not only in the silent era but also in film noir through lighting effects and camera angles which characterize the work of major noir directors like Fritz Lang,Billy Wilder,and Orson Welles,who knew everything about the unutterable mysteries hidden on the dark side of the screen. 展开更多
关键词 film noir black and white cinema dark side RESISTANCE
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Evie's Ethical Choices in the World of Noir Ethical Literary Reading of Judy Blundell' s What I Saw and How I Lied
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作者 YANG Chun 《Sino-US English Teaching》 2015年第6期430-434,共5页
In the novel What I Saw and How I Lied (2008), Judy Blundell presents readers a world of noir where so many lies are around the innocent protagonist, 15-year-old girl Evie. It is a challenge for Evie to probe into t... In the novel What I Saw and How I Lied (2008), Judy Blundell presents readers a world of noir where so many lies are around the innocent protagonist, 15-year-old girl Evie. It is a challenge for Evie to probe into the heart of the deceptions and make ethical choices between good and evil. After experiencing the path from error to truth, from confusion to clarity, and unconsciousness to consciousness, Evie comes to realize the corruption and evils of the society and in an epiphany, obtains a self-knowledge which leads to her initiation. Through analyzing the ethical predicament and ethical choices of the protagonist Evie as well as the negative living environment around her, the present paper aims to interrogate the moral issues of truth, lie, justice, greed, fidelity, and betrayal so as to give readers a better understanding of the theme of initiation in the novel. 展开更多
关键词 What I Saw and How 1 Lied ethical choices the world of noir INITIATION
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Domestic noir in Anglo-American Literature
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作者 Maria Antónia Lima 《Journal of Literature and Art Studies》 2021年第11期841-846,共6页
In order to highlight the contribution of Literature to the study of Domestic Violence,this essay will reflect on the relevance of some Anglo-American literary works,integrated in the Domestic Gothic or Domestic Noir,... In order to highlight the contribution of Literature to the study of Domestic Violence,this essay will reflect on the relevance of some Anglo-American literary works,integrated in the Domestic Gothic or Domestic Noir,a subgenre of the psychological thriller,distinguished by the peculiarity of representing a woman in danger as its main character.The family can be the most commonly considered luminous space of harmony,affection and quiet domesticity,but everything can turn upside down whenever this stereotype is reversed drastically.The so-called domestic noir,a new genre popularized in 2013,deals with these dualities,demonstrating that gothic fiction has always been interested in family conflicts and domestic violence in its most varied forms,turning them into sources of terror so relevant to our time. 展开更多
关键词 Domestic Noir domestic gothic domestic violence Anglo-American literature
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Noir & Blanc——“异域欣快”
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《流行色》 2011年第6期108-109,共2页
又一波瑞典时尚将撞击上海。这一次,以部落文化为题材,以"异域欣快"为名的Noir&Blanc(娜衣)时装秀,是一场与Jazz du Funk舞团联手的跨界演出,在时尚与现代舞艺术中自由来去。Noir&Blanc的两位女性设计师Petra Thoms(... 又一波瑞典时尚将撞击上海。这一次,以部落文化为题材,以"异域欣快"为名的Noir&Blanc(娜衣)时装秀,是一场与Jazz du Funk舞团联手的跨界演出,在时尚与现代舞艺术中自由来去。Noir&Blanc的两位女性设计师Petra Thoms(沛茶)和Linnea Carlgren(琳娜),与Jazz du Funk的舞者们重新定义传统秀场的秀演形式,只为给中国观众们带来难忘今宵。2011年4月9日在800秀,体验"异域欣快"与" 展开更多
关键词 Blanc Noir 难忘今宵 男与女 令人目眩 视觉化 段名 界中
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未来,已悄然接入现实
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《科学中国人》 2026年第2期70-71,共2页
投影仪“专业级选手”极米Titan Noir Max系列投影仪搭载了先进的动态光圈系统与精准调校的光学组件。其动态光圈系统实现了10 000∶1的原生对比度,重新设计的SST DMD架构(单流传输数字微镜器件架构)可承受更高的光功率密度。同时,升级... 投影仪“专业级选手”极米Titan Noir Max系列投影仪搭载了先进的动态光圈系统与精准调校的光学组件。其动态光圈系统实现了10 000∶1的原生对比度,重新设计的SST DMD架构(单流传输数字微镜器件架构)可承受更高的光功率密度。同时,升级的散热通道能够在芯片层面高效散热,即便在严苛的投影环境下,也能确保亮度持续稳定输出,减少设备热应力,显著提升产品生命周期稳定性。 展开更多
关键词 投影仪 极米Titan Noir Max系列
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浅析梅西安的《LE MERLE NOIR》
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作者 田文 《时代文学(下半月)》 2015年第11期70-71,共2页
法国作曲家梅西安的作品《鸟类志》运用从各地采集、记录的鸟歌旋律进行的创作,是极富代表性的作品。《Le merle noir》是其中的一个乐章,为钢琴和长笛演奏,本文将以该乐章为研究对象,分析其结构与音乐发展特点,了解作曲家在该部作品中... 法国作曲家梅西安的作品《鸟类志》运用从各地采集、记录的鸟歌旋律进行的创作,是极富代表性的作品。《Le merle noir》是其中的一个乐章,为钢琴和长笛演奏,本文将以该乐章为研究对象,分析其结构与音乐发展特点,了解作曲家在该部作品中的创作特色和独特的艺术特点。 展开更多
关键词 梅西安 《鸟类志》 《Le merle noir》 创作特色
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Femme Fatale in French Film Noir
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作者 Gegen 《Advances in Humanities Research》 2021年第1期1-5,共5页
The term film noir was coined by two French film critics Borde and Chaumenton in 1956 to describe American detective stories mode in the 1940s.Noir films were seen as a counter-cultural movement within Hollywood at th... The term film noir was coined by two French film critics Borde and Chaumenton in 1956 to describe American detective stories mode in the 1940s.Noir films were seen as a counter-cultural movement within Hollywood at that time,and the French new wave continued this feature in the 1960s.Therefore,the term noir itself connects the Frenchness and Americanness.This paper tends to map out the film noir sensibilities in French content through unfolding the characteristics of femme fatale in two French noir films Jean-Luc Godard’s A bout de souffle(Breathless)(1960)and Jean-Jacques Beineix’s Diva(1981). 展开更多
关键词 Film Noir Femme Fatale AMERICANISATION French New Wave
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汉语颜色词“白”、“黑”与法语颜色词“Blanc”、“Noir”对比分析
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作者 林俊杰 《明日风尚》 2018年第4期376-376,390,共2页
不同的颜色词在不同国家、不同语言、不同文化中可以代表不同的象征意义。我们不仅注意到了颜色词的基本含义和象征意义,同时也注意到了两种颜色词在它们的国家、文化以及不同历史背景下的不同含义。汉法两种语言的'黑'和'... 不同的颜色词在不同国家、不同语言、不同文化中可以代表不同的象征意义。我们不仅注意到了颜色词的基本含义和象征意义,同时也注意到了两种颜色词在它们的国家、文化以及不同历史背景下的不同含义。汉法两种语言的'黑'和'白'是特别丰富的两种颜色词,在某些情况下可以表示不同的颜色词的联想意义。以下的研究将基于汉语'黑''白'与法语'Noir''Blanc'颜色词两种基本颜色词联想意义进行简要的比较,找出它们的联想意义的相似性和不同点,并找出两种语言在使用颜色词时的异同点。 展开更多
关键词 颜色词“黑” “白” “Noir” “Blanc” 对比分
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Noir Désir:风会带走黑色的欲望
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作者 Chasez 《音乐大观》 2008年第1期18-19,共2页
  关于黄价   志宁@929在我眼里,黄玠是一个音乐天才……   问:是你教黄价弹吉他的吧.   志宁:我只能说,他是个天才,在我刚开始只是想敷衍他,教他几个唱番石榴歌的和弦时,我就惊讶地发现了!他对歌曲的敏锐度,尤其是和弦和歌...   关于黄价   志宁@929在我眼里,黄玠是一个音乐天才……   问:是你教黄价弹吉他的吧.   志宁:我只能说,他是个天才,在我刚开始只是想敷衍他,教他几个唱番石榴歌的和弦时,我就惊讶地发现了!他对歌曲的敏锐度,尤其是和弦和歌词,都有过人的天分,从大学到现在我从来没怀疑过他的才华.…… 展开更多
关键词 SIR Noir D 摇滚乐
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Genetically divergent’Candidatus Phytoplasma solani’isolates in Croatian vineyard pathosystems suggest complex epidemiological networks
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作者 Jelena Plavec Goran Ivancan +2 位作者 Dijana Skoric Xavier Foissac Martina Seruga Music 《Phytopathology Research》 2024年第1期318-336,共19页
Candidatus Phytoplasma solani’(CPs),a phytoplasma endemic to the Euro-Mediterranean basin is a causative agent of several plant diseases,including the grapevine yellows disease“bois noir”(BN).As different CPs strai... Candidatus Phytoplasma solani’(CPs),a phytoplasma endemic to the Euro-Mediterranean basin is a causative agent of several plant diseases,including the grapevine yellows disease“bois noir”(BN).As different CPs strains have been shown to have different ecological reservoirs and pathways for spread,the genetic characterization of CPs strains is a prerequisite,and better control of BN relies on the identification of reservoir plants.The variability of the phytoplasma genotypes involved in the BN pathosystem in Croatian vineyards was assessed by a multilocus sequence typing(MLST)approach.The genotyping was performed on selected grapevine,wild plants,and insects collected within the eleven years of national survey conducted in all Croatian viticultural regions.The extensive tuf,secY,stamp,and vmp1 genes-based MLST analyses revealed two new genotypes for stamp and vmp1 genes,designated as ST59 and V28,respectively,and overall identified 28 different CPs MLST genotypes.The prevalent MLST genotype in grapevine CPsSqt21(S6/ST6/V18/tuf-b2)was widespread in nine counties across Uplands,Slavonia,and Danube wine regions and was affiliated to the known vector Hyalesthes obsoletus and to Urtica dioica.The other two most frequent genotypes were the U.dioica-associated CPsSqt28(S39/ST46/V3/tuf-a)and the C.arvensis-associated CPsSqt2(S1/ST9/V4/tuf-b1).CPs of different vmp1 genotypes was also detected in Cixius wagneri specimens originating from different parts of Croatia.In addition,CPs was detected in several Dichtyophara europaea insects and in two new potential plant reservoirs Ailanthus altissima and Robinia pseudoacacia.The substantial number of found MLST genotypes indicates the presence of several independent epidemiological cycles and is certainly a consequence of a unique geographical position of Croatia,bridging the different eco-climatic areas of central and south-eastern Europe. 展开更多
关键词 Grapevine Bois noir Sequence variants MLST Molecular epidemiology
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