Objective:The current standard D2 lymphadenectomy for gastric cancer(GC)includes dissection of lymph nodes(LNs)along the proper hepatic artery(No.12 a),however,the survival benefit remains controversial.The purpose of...Objective:The current standard D2 lymphadenectomy for gastric cancer(GC)includes dissection of lymph nodes(LNs)along the proper hepatic artery(No.12 a),however,the survival benefit remains controversial.The purpose of this study was to evaluate the pattern of No.12 a LN metastasis(LNM)in GC and explore the indications for No.12 a LN dissection.Methods:Medical records of 413 consecutive GC patients who underwent curative surgery in Zhongshan Hospital,Fudan University between January 2015 and December 2018 were enrolled and reviewed retrospectively.The correlation between No.12 a LNM and clinicopathologic characteristics of patients was analyzed.Results:The overall incidence of No.12 a LNM was 2.67%(11/413).Tumor location(P=0.012),depth of tumor infiltration(P<0.01)and N stage(P=0.018)were significant factors associated with No.12 a LNM.All the tumors with No.12 a LNM involved the lower third of the stomach and were in T3-4 stages.Patients with No.12 a LNM had extensive LNM than those without(20.91±4.25 vs.5.0±0.54,P<0.001).For advanced GC patients(stage III/IV)with tumors involving the lower third of the stomach,the incidence of No.12 a LNM increased to 10.7%(11/103).Patients with No.12 a LNM had a significantly poorer recurrence-free survival(RFS)(P=0.005)and overall survival(OS)(P=0.017).According to the result of multivariable Cox regression,No.12 a LNM was not an independent impact factor on RFS and OS.Conclusions:The overall incidence of No.12 a LNM was low but it was much higher in GC patients who had very advanced tumors involving the lower third of the stomach.No.12 a LN dissection should be considered for these patients to improve the survival outcomes.展开更多
BACKGROUND Controversy over the issue that No.12a lymph node involvement is distant or regional metastasis remains,and the possible inclusion of 12a lymph nodes in D2 lymphadenectomy is unclear.As reported,gastric can...BACKGROUND Controversy over the issue that No.12a lymph node involvement is distant or regional metastasis remains,and the possible inclusion of 12a lymph nodes in D2 lymphadenectomy is unclear.As reported,gastric cancer(GC)located in the lower third is highly related to the metastasis of station 12a lymph nodes.AIM To investigate whether the clinicopathological factors and metastasis status of other perigastric nodes can predict station 12a lymph node metastasis and evaluate the prognostic significance of station 12a lymph node dissection in patients with lower-third GC.METHODS A total of 147 patients with lower-third GC who underwent D2 or D2+lymphadenectomy,including station 12a lymph node dissection,were included in this retrospective study from June 2003 to March 2011.Survival prognoses were compared between patients with or without station 12a lymph node metastasis.Logistic regression analyses were used to clarify the association between station 12a lymph node metastasis and clinicopathological factors or metastasis status of other perigastric nodes.The metastasis status of each regional lymph node was evaluated to identify the possible predictors of station 12a lymph node metastasis.RESULTS Metastasis to station 12a lymph nodes was observed in 18 patients with lowerthird GC,but not in 129 patients.The incidence of station 12a lymph node involvement was reported as 12.2%in patients with lower-third GC.The overall survival of patients without station 12a lymph node metastasis was significantly better than that of patients with station 12a metastasis(P<0.001),which could also be seen in patients with or without extranodal soft tissue invasion.Station 12a lymph node metastasis and extranodal soft tissue invasion were identified as independent predictors of poor prognosis in patients with lower-third GC.Advanced pN stage was defined as independent risk factor significantly correlated with station 12a lymph node positivity.Station 3 lymph node staus was also proven to be significantly correlated with station 12a lymph node involvement.CONCLUSION Metastasis of station 12a lymph nodes could be considered an independent prognosis factor for patients with lower-third GC.The dissection of station 12a lymph nodes may not be ignored in D2 or D2+lymphadenectomy due to difficulties in predicting station 12a lymph node metastasis.展开更多
[Objective] The research aimed to understand the high-yielding technique in intersubspecific hybrid rice Yongyou No.12. [Method] The correlation analysis, regression analysis and path analysis of intersubspecific hybr...[Objective] The research aimed to understand the high-yielding technique in intersubspecific hybrid rice Yongyou No.12. [Method] The correlation analysis, regression analysis and path analysis of intersubspecific hybrid rice Yongyou No. 12 were conducted based on the data of its ear, grain and weight with yield higher than 10 500 kg/hm^2. [Result] The enhancement of effective ears would restrain the number of per ear total grains. It was found that the direct contributions of main economic traits to yield were determined to be effective ear〉total grains per ear〉 seed setting rate〉l 000-grain weight. [Conclusion] The high-yielding cultivation techniques were suggested as follows： besides necessary ear number, grain number per ear should be focused with a consideration to 1 000-grain weight.展开更多
This study reconstructed the annual mass balance(MB)of Laohugou Glacier No.12 in the western Qilian Mountains during 1961–2015.The annual MB was calculated based on a temperature-index and an accumulation model with ...This study reconstructed the annual mass balance(MB)of Laohugou Glacier No.12 in the western Qilian Mountains during 1961–2015.The annual MB was calculated based on a temperature-index and an accumulation model with inputs of daily air temperature and precipitation recorded by surrounding meteorological stations.The model was calibrated by in-situ MB measurements conducted on the glacier during 2010–2015.Change in constructed annual MB had three phases.During Phase Ⅰ(1961-1984),glacier-wide MB values were slightly positive with an average MB of 24±276 mm w.e.(water equivalent).During Phase Ⅱ(1984-1995),the MB values became slightly negative with an average MB of?50±276 mm w.e..The most negative MB values were found during Phase Ⅲ(1996–2015),with an average MB of?377±276 mm w.e.Climatic analysis showed that the warming led to accelerated glacier mass loss despite a persistent increase of precipitation during the analysis period.However,an increase of black carbon deposited on the glacier surface since the 1980s could have contributed to intensified glacier melt.From simulations and measurements of MB on the Urumqi Glacier No.1,26%of glacier melt caused by black carbon could be identified.展开更多
In June 2006, samples were collected from a 90 cm snow-pit at an elevation of 5 040 m a.s.l, in the northern branch firn basin of the Glacier No. 12, Laohugou Valley, in the western part of Qilian Mountain, China. Oxy...In June 2006, samples were collected from a 90 cm snow-pit at an elevation of 5 040 m a.s.l, in the northern branch firn basin of the Glacier No. 12, Laohugou Valley, in the western part of Qilian Mountain, China. Oxygen isotopes （6180） and major soluble ions were measured. Results showed that Ca2＋ is the dominant cation, and SO42 is the dominant anion. All major ions have close positive correlations with eachother except NO3 and NH4＋. 6180 show positive correlation with air temperature. The method of correlation analysis, sea-salt ion tracer and trend analysis were used to determine the source of the chemical components. The correlation analysis and HYSPLIT backward trajectory analysis suggest that atmospheric soluble dust species dominate the chemical signature.展开更多
Glaciers were solid reservoirs and important water resources in western China,but they were retreating significantly in context of global warming.Laohugou Glacier No.12 was the largest valley glacier in Qilian Mountai...Glaciers were solid reservoirs and important water resources in western China,but they were retreating significantly in context of global warming.Laohugou Glacier No.12 was the largest valley glacier in Qilian Mountains.In this study,realtime kinematic(RTK)data,topographic map and World View-2 satellite imagery were used to measure changes in terminus,extent and volume of Laohugou Glacier No.12.Results showed that Laohugou Glacier No.12 was shrinking significantly since 1957.From1960 to 2015,the terminus reduction of Laohugou Glacier No.12 was 402.96 m(3.99%)in total,and glacier length decreased to 9.7 km from 10.1 km.Reduction of glacier area and volume were the most obvious.From 1957 to 2015,glacier area and volume decreased by 1.54 km^2(7.03%)and 0.1816 km^3,respectively.Reduction trend of terminus and area was slowing in 1950-1980s,even stable for a period in the mid-1980s,and then accelerated.Ice core analysis result and nearly meteorological station data shown an increasing trend of temperature in 1957-2015,it was a main reason of continuous retreating of Laohugou Glacier No.12.展开更多
The Laohugou Glacier No. 12 is the largest valley glacier in Qilian Mountains, which is located in northem Qinghai-Tibet Plateau. Movement is the basic characteristic of glaciers, and is also an important distinction ...The Laohugou Glacier No. 12 is the largest valley glacier in Qilian Mountains, which is located in northem Qinghai-Tibet Plateau. Movement is the basic characteristic of glaciers, and is also an important distinction from other terrestrial natural ice. Glacier changes not only reflect climate change, but also play an important role in humanity society. In the arid regions of western China, glaciers are becoming an important water source. We use the GPS receiver （South-Lingrui $82） as data platform with the aid of RTK measurement technology to observe the surface velocity of Laohugou Glacier No. 12. Surface velocity data shows that the maximum value appears at an altitude of 4,750-4,850 m during the period of 2008-2009. During this period, the west branch surface velocity reached 32.6 m per year at an altitude near 4,830 m, the east branch surface velocity reached 32.4 m per year at the altitude near 4,770 m. Comparing the surface velocity data during 2008-2009 with observation results in 1959, the glacier velocity slowed down about 11%.展开更多
In June 2006,a 20.12 m shallow ice core was recovered from an elevation of 5,040 m in the northern branch firn basin of No.12 Glacier,Great Snow Mountain,in the western part of Qilian Mountain,China.Isotopes(δ 18 O),...In June 2006,a 20.12 m shallow ice core was recovered from an elevation of 5,040 m in the northern branch firn basin of No.12 Glacier,Great Snow Mountain,in the western part of Qilian Mountain,China.Isotopes(δ 18 O),major soluble ions,and radionuclide(β-activity) measurements from the ice core revealed a 46-year record(1960-2006).In this paper,the method of sea-salt ion tracer,correlation analysis and trend analysis were used in this research to confirm the source of the chemical composition.The correlation analysis and HYSPLIT backward trajectory analysis suggests that atmospheric soluble dust species dominate the chemical signature.展开更多
The mung bean variety Ji Heilv No.12 was bred by Institute of Characteristic Crop Research, Chongqing Academy of Agricultural Sciences and Institute of Food and Oil Crops, Hebei Academy of Agricultural and Forestry Sc...The mung bean variety Ji Heilv No.12 was bred by Institute of Characteristic Crop Research, Chongqing Academy of Agricultural Sciences and Institute of Food and Oil Crops, Hebei Academy of Agricultural and Forestry Sciences. using Jilv 9and Jilv 7 as female and male parent respectively,with pedigree method. Ji Heilv No.12 is a new variety with features of high and stable yield,broad adaptability and strong resistance in yield trails during 2011-2012; it was approved and released by Chongqing Provincial Committee of Crop Variety Identification in 2012,suitable for cultivating in most area of Chongqing.展开更多
Effect of row space and planting density on yield of Miandan No.12 was studied. The test included four row spaces and two planting densities. Specifically, four row spaces were 50, 67, 83 and 100 cm and two planting d...Effect of row space and planting density on yield of Miandan No.12 was studied. The test included four row spaces and two planting densities. Specifically, four row spaces were 50, 67, 83 and 100 cm and two planting densities were 42 000 and 48 000 plant/hm2. The results showed that Miandan No.12 reached the highest yield when row space was 50 cm and planting density was 48 000 plantJhm2 and Miandan No.12 got the lowest yield when row space was 100 cm and planting density was 42 000 plants/hm2.展开更多
基金supported by National Natural Science Fund(No.31842033)。
文摘Objective:The current standard D2 lymphadenectomy for gastric cancer(GC)includes dissection of lymph nodes(LNs)along the proper hepatic artery(No.12 a),however,the survival benefit remains controversial.The purpose of this study was to evaluate the pattern of No.12 a LN metastasis(LNM)in GC and explore the indications for No.12 a LN dissection.Methods:Medical records of 413 consecutive GC patients who underwent curative surgery in Zhongshan Hospital,Fudan University between January 2015 and December 2018 were enrolled and reviewed retrospectively.The correlation between No.12 a LNM and clinicopathologic characteristics of patients was analyzed.Results:The overall incidence of No.12 a LNM was 2.67%(11/413).Tumor location(P=0.012),depth of tumor infiltration(P<0.01)and N stage(P=0.018)were significant factors associated with No.12 a LNM.All the tumors with No.12 a LNM involved the lower third of the stomach and were in T3-4 stages.Patients with No.12 a LNM had extensive LNM than those without(20.91±4.25 vs.5.0±0.54,P<0.001).For advanced GC patients(stage III/IV)with tumors involving the lower third of the stomach,the incidence of No.12 a LNM increased to 10.7%(11/103).Patients with No.12 a LNM had a significantly poorer recurrence-free survival(RFS)(P=0.005)and overall survival(OS)(P=0.017).According to the result of multivariable Cox regression,No.12 a LNM was not an independent impact factor on RFS and OS.Conclusions:The overall incidence of No.12 a LNM was low but it was much higher in GC patients who had very advanced tumors involving the lower third of the stomach.No.12 a LN dissection should be considered for these patients to improve the survival outcomes.
文摘BACKGROUND Controversy over the issue that No.12a lymph node involvement is distant or regional metastasis remains,and the possible inclusion of 12a lymph nodes in D2 lymphadenectomy is unclear.As reported,gastric cancer(GC)located in the lower third is highly related to the metastasis of station 12a lymph nodes.AIM To investigate whether the clinicopathological factors and metastasis status of other perigastric nodes can predict station 12a lymph node metastasis and evaluate the prognostic significance of station 12a lymph node dissection in patients with lower-third GC.METHODS A total of 147 patients with lower-third GC who underwent D2 or D2+lymphadenectomy,including station 12a lymph node dissection,were included in this retrospective study from June 2003 to March 2011.Survival prognoses were compared between patients with or without station 12a lymph node metastasis.Logistic regression analyses were used to clarify the association between station 12a lymph node metastasis and clinicopathological factors or metastasis status of other perigastric nodes.The metastasis status of each regional lymph node was evaluated to identify the possible predictors of station 12a lymph node metastasis.RESULTS Metastasis to station 12a lymph nodes was observed in 18 patients with lowerthird GC,but not in 129 patients.The incidence of station 12a lymph node involvement was reported as 12.2%in patients with lower-third GC.The overall survival of patients without station 12a lymph node metastasis was significantly better than that of patients with station 12a metastasis(P<0.001),which could also be seen in patients with or without extranodal soft tissue invasion.Station 12a lymph node metastasis and extranodal soft tissue invasion were identified as independent predictors of poor prognosis in patients with lower-third GC.Advanced pN stage was defined as independent risk factor significantly correlated with station 12a lymph node positivity.Station 3 lymph node staus was also proven to be significantly correlated with station 12a lymph node involvement.CONCLUSION Metastasis of station 12a lymph nodes could be considered an independent prognosis factor for patients with lower-third GC.The dissection of station 12a lymph nodes may not be ignored in D2 or D2+lymphadenectomy due to difficulties in predicting station 12a lymph node metastasis.
基金Suppored by the Science and Technology Plan of Taizhou City(121KY15)~~
文摘[Objective] The research aimed to understand the high-yielding technique in intersubspecific hybrid rice Yongyou No.12. [Method] The correlation analysis, regression analysis and path analysis of intersubspecific hybrid rice Yongyou No. 12 were conducted based on the data of its ear, grain and weight with yield higher than 10 500 kg/hm^2. [Result] The enhancement of effective ears would restrain the number of per ear total grains. It was found that the direct contributions of main economic traits to yield were determined to be effective ear〉total grains per ear〉 seed setting rate〉l 000-grain weight. [Conclusion] The high-yielding cultivation techniques were suggested as follows： besides necessary ear number, grain number per ear should be focused with a consideration to 1 000-grain weight.
基金The work were supported by the Chinese Academy of Sciences(No.QYZDJ-SSW-DQC039)the National Natural Science Foundation of China(Nos.41630754,41721091)+2 种基金the Science and Technology planning Project of Gansu Province(No.18JR4RA002)the Project of the State Key Laboratory of Cryospheric Sciences(Nos.SKLCS-OP-2018-06,SKLCS-OP-2019-01)Open Foundation of State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering(No.2017490711).
文摘This study reconstructed the annual mass balance(MB)of Laohugou Glacier No.12 in the western Qilian Mountains during 1961–2015.The annual MB was calculated based on a temperature-index and an accumulation model with inputs of daily air temperature and precipitation recorded by surrounding meteorological stations.The model was calibrated by in-situ MB measurements conducted on the glacier during 2010–2015.Change in constructed annual MB had three phases.During Phase Ⅰ(1961-1984),glacier-wide MB values were slightly positive with an average MB of 24±276 mm w.e.(water equivalent).During Phase Ⅱ(1984-1995),the MB values became slightly negative with an average MB of?50±276 mm w.e..The most negative MB values were found during Phase Ⅲ(1996–2015),with an average MB of?377±276 mm w.e.Climatic analysis showed that the warming led to accelerated glacier mass loss despite a persistent increase of precipitation during the analysis period.However,an increase of black carbon deposited on the glacier surface since the 1980s could have contributed to intensified glacier melt.From simulations and measurements of MB on the Urumqi Glacier No.1,26%of glacier melt caused by black carbon could be identified.
基金supported by the Foundation for Excellent Youth Scholars of CAREERI, CAS (No. 51Y25B01)the National Natural Science Foundation of China (No. 41301064)the National Basic Research Program of China (No. 2007CB411501)
文摘In June 2006, samples were collected from a 90 cm snow-pit at an elevation of 5 040 m a.s.l, in the northern branch firn basin of the Glacier No. 12, Laohugou Valley, in the western part of Qilian Mountain, China. Oxygen isotopes （6180） and major soluble ions were measured. Results showed that Ca2＋ is the dominant cation, and SO42 is the dominant anion. All major ions have close positive correlations with eachother except NO3 and NH4＋. 6180 show positive correlation with air temperature. The method of correlation analysis, sea-salt ion tracer and trend analysis were used to determine the source of the chemical components. The correlation analysis and HYSPLIT backward trajectory analysis suggest that atmospheric soluble dust species dominate the chemical signature.
基金supported by the National Foundational Scientific and Technological Work Programs of the Ministry of Science and Technology of China (grant No. 2013FY111400)the Project from the State Key Laboratory of Cryospheric Sciences (grant No. SKLCS-ZZ-2017)the National Key Geographic Conditions Monitoring: The Project of Basic National Geographical Conditions Monitoring in 2015
文摘Glaciers were solid reservoirs and important water resources in western China,but they were retreating significantly in context of global warming.Laohugou Glacier No.12 was the largest valley glacier in Qilian Mountains.In this study,realtime kinematic(RTK)data,topographic map and World View-2 satellite imagery were used to measure changes in terminus,extent and volume of Laohugou Glacier No.12.Results showed that Laohugou Glacier No.12 was shrinking significantly since 1957.From1960 to 2015,the terminus reduction of Laohugou Glacier No.12 was 402.96 m(3.99%)in total,and glacier length decreased to 9.7 km from 10.1 km.Reduction of glacier area and volume were the most obvious.From 1957 to 2015,glacier area and volume decreased by 1.54 km^2(7.03%)and 0.1816 km^3,respectively.Reduction trend of terminus and area was slowing in 1950-1980s,even stable for a period in the mid-1980s,and then accelerated.Ice core analysis result and nearly meteorological station data shown an increasing trend of temperature in 1957-2015,it was a main reason of continuous retreating of Laohugou Glacier No.12.
基金supported by the Chinese Key Basic Research Development Project (973) (Grant Number: 2007CB411501)the National Basic Work Program of Chinese Ministry of Science and Technology "Investigation of glacier resources and their variations in China" (Grant number: 2006FY110200)the Self-determination Project of State Key Laboratory of Cryospheric Sciences (Grant number: SKLCS09-04)
文摘The Laohugou Glacier No. 12 is the largest valley glacier in Qilian Mountains, which is located in northem Qinghai-Tibet Plateau. Movement is the basic characteristic of glaciers, and is also an important distinction from other terrestrial natural ice. Glacier changes not only reflect climate change, but also play an important role in humanity society. In the arid regions of western China, glaciers are becoming an important water source. We use the GPS receiver （South-Lingrui $82） as data platform with the aid of RTK measurement technology to observe the surface velocity of Laohugou Glacier No. 12. Surface velocity data shows that the maximum value appears at an altitude of 4,750-4,850 m during the period of 2008-2009. During this period, the west branch surface velocity reached 32.6 m per year at an altitude near 4,830 m, the east branch surface velocity reached 32.4 m per year at the altitude near 4,770 m. Comparing the surface velocity data during 2008-2009 with observation results in 1959, the glacier velocity slowed down about 11%.
基金supported by the National Basic Research Program of China (2007CB411501)the National Essential Scientific Program of the Ministry of Scienceand Technology of the People’s Republic of China(2006FY110200)
文摘In June 2006,a 20.12 m shallow ice core was recovered from an elevation of 5,040 m in the northern branch firn basin of No.12 Glacier,Great Snow Mountain,in the western part of Qilian Mountain,China.Isotopes(δ 18 O),major soluble ions,and radionuclide(β-activity) measurements from the ice core revealed a 46-year record(1960-2006).In this paper,the method of sea-salt ion tracer,correlation analysis and trend analysis were used in this research to confirm the source of the chemical composition.The correlation analysis and HYSPLIT backward trajectory analysis suggests that atmospheric soluble dust species dominate the chemical signature.
基金Supported by Chongqing Science&Technology Commission(cstc2016shmszx80116csct2012jj A80042+5 种基金cstc2013yykfc800022015cstc-jbky-005072015cstc-jbky-00508)National Modern Agricultural Industry Technology System(CARS-09)Chongqing Finance Program(NKY-2016AB009NKY-2016AA002)
文摘The mung bean variety Ji Heilv No.12 was bred by Institute of Characteristic Crop Research, Chongqing Academy of Agricultural Sciences and Institute of Food and Oil Crops, Hebei Academy of Agricultural and Forestry Sciences. using Jilv 9and Jilv 7 as female and male parent respectively,with pedigree method. Ji Heilv No.12 is a new variety with features of high and stable yield,broad adaptability and strong resistance in yield trails during 2011-2012; it was approved and released by Chongqing Provincial Committee of Crop Variety Identification in 2012,suitable for cultivating in most area of Chongqing.
基金Supported by National Food High-yield Science and Technology Project(2012BAD04B13-3)~~
文摘Effect of row space and planting density on yield of Miandan No.12 was studied. The test included four row spaces and two planting densities. Specifically, four row spaces were 50, 67, 83 and 100 cm and two planting densities were 42 000 and 48 000 plant/hm2. The results showed that Miandan No.12 reached the highest yield when row space was 50 cm and planting density was 48 000 plantJhm2 and Miandan No.12 got the lowest yield when row space was 100 cm and planting density was 42 000 plants/hm2.
