In the context of global digital transformation and the rising prominence of maker education,this study explores the innovative integration of digital modeling technologies with traditional Nixing Pottery craftsmanshi...In the context of global digital transformation and the rising prominence of maker education,this study explores the innovative integration of digital modeling technologies with traditional Nixing Pottery craftsmanship.By constructing a teaching framework under maker education theory,the research investigates how 3D modeling,CAD design,and 3D printing technologies can empower learners to address challenges in cultural heritage preservation and artistic innovation.Through experimental teaching and case analysis,the study verifies that this integrated approach significantly enhances learners’digital literacy,creative thinking,and cultural identity while optimizing Nixing Pottery’s production processes and design possibilities.The findings contribute to theoretical models of technology-enhanced craft education and provide practical pathways for the digital transformation of intangible cultural heritage.展开更多
Spinal cord ischemia-reperfusion injury,a severe form of spinal cord damage,can lead to sensory and motor dysfunction.This injury often occurs after traumatic events,spinal cord surgeries,or thoracoabdominal aortic su...Spinal cord ischemia-reperfusion injury,a severe form of spinal cord damage,can lead to sensory and motor dysfunction.This injury often occurs after traumatic events,spinal cord surgeries,or thoracoabdominal aortic surgeries.The unpredictable nature of this condition,combined with limited treatment options,poses a significant burden on patients,their families,and society.Spinal cord ischemia-reperfusion injury leads to reduced neuronal regenerative capacity and complex pathological processes.In contrast,mitophagy is crucial for degrading damaged mitochondria,thereby supporting neuronal metabolism and energy supply.However,while moderate mitophagy can be beneficial in the context of spinal cord ischemia-reperfusion injury,excessive mitophagy may be detrimental.Therefore,this review aims to investigate the potential mechanisms and regulators of mitophagy involved in the pathological processes of spinal cord ischemia-reperfusion injury.The goal is to provide a comprehensive understanding of recent advancements in mitophagy related to spinal cord ischemia-reperfusion injury and clarify its potential clinical applications.展开更多
The molybdenum disilicide (MoSi2 ) based heating element is more and more important in modern industries relating to thermal treatment, melting and sintering due to its high working temperature. In China, the consum...The molybdenum disilicide (MoSi2 ) based heating element is more and more important in modern industries relating to thermal treatment, melting and sintering due to its high working temperature. In China, the consumption of the MoSi2 heating element continues to increase with development and upgrading of industries. However, the MoSi2 heating element .from local manufacturers still has poor quality and thus results in waste of precious molybdenum resource. In this review, the recent research results of production process of MoSi2 heating elements were briefly summarized. The purity and particle size distribution of starting MoSi2 powder as well as the mixing and sintering processes were identified as major impact fators on the performance of MoSi2 heating elements. This review points out the improving direction for local MoSi2 heating elements.展开更多
文摘In the context of global digital transformation and the rising prominence of maker education,this study explores the innovative integration of digital modeling technologies with traditional Nixing Pottery craftsmanship.By constructing a teaching framework under maker education theory,the research investigates how 3D modeling,CAD design,and 3D printing technologies can empower learners to address challenges in cultural heritage preservation and artistic innovation.Through experimental teaching and case analysis,the study verifies that this integrated approach significantly enhances learners’digital literacy,creative thinking,and cultural identity while optimizing Nixing Pottery’s production processes and design possibilities.The findings contribute to theoretical models of technology-enhanced craft education and provide practical pathways for the digital transformation of intangible cultural heritage.
基金supported by Cuiying Scientific and Technological Innovation Program of Second Hospital of Lanzhou University,Nos.CY2023-QN-B18(to YD),2020QN-16(to YZ)the Natural Science Foundation of Gansu Province,No.22JR11RA082(to YZ)Key R&D Plan of Gansu Provincial Department of Science and Technology-Social Development Projects,No.23YFFA0043(to XK).
文摘Spinal cord ischemia-reperfusion injury,a severe form of spinal cord damage,can lead to sensory and motor dysfunction.This injury often occurs after traumatic events,spinal cord surgeries,or thoracoabdominal aortic surgeries.The unpredictable nature of this condition,combined with limited treatment options,poses a significant burden on patients,their families,and society.Spinal cord ischemia-reperfusion injury leads to reduced neuronal regenerative capacity and complex pathological processes.In contrast,mitophagy is crucial for degrading damaged mitochondria,thereby supporting neuronal metabolism and energy supply.However,while moderate mitophagy can be beneficial in the context of spinal cord ischemia-reperfusion injury,excessive mitophagy may be detrimental.Therefore,this review aims to investigate the potential mechanisms and regulators of mitophagy involved in the pathological processes of spinal cord ischemia-reperfusion injury.The goal is to provide a comprehensive understanding of recent advancements in mitophagy related to spinal cord ischemia-reperfusion injury and clarify its potential clinical applications.
文摘The molybdenum disilicide (MoSi2 ) based heating element is more and more important in modern industries relating to thermal treatment, melting and sintering due to its high working temperature. In China, the consumption of the MoSi2 heating element continues to increase with development and upgrading of industries. However, the MoSi2 heating element .from local manufacturers still has poor quality and thus results in waste of precious molybdenum resource. In this review, the recent research results of production process of MoSi2 heating elements were briefly summarized. The purity and particle size distribution of starting MoSi2 powder as well as the mixing and sintering processes were identified as major impact fators on the performance of MoSi2 heating elements. This review points out the improving direction for local MoSi2 heating elements.