Chitin synthase(CHS)is a potential agricultural and therapeutic target.Recently,the crystal structures of CHS from Phytophthora sojae(PsChs1)and Candida albicans(CaChs2)were reported.Here,we highlight the achievements...Chitin synthase(CHS)is a potential agricultural and therapeutic target.Recently,the crystal structures of CHS from Phytophthora sojae(PsChs1)and Candida albicans(CaChs2)were reported.Here,we highlight the achievements of PsChs1 and CaChs2,which would give some clues for design new inhibitor targeted upon CHS.展开更多
基金supported in part by the National Key Research and Development Program of China(2022YFD1700204).
文摘Chitin synthase(CHS)is a potential agricultural and therapeutic target.Recently,the crystal structures of CHS from Phytophthora sojae(PsChs1)and Candida albicans(CaChs2)were reported.Here,we highlight the achievements of PsChs1 and CaChs2,which would give some clues for design new inhibitor targeted upon CHS.