Scientific analysis and determination of land use lays foundation for regional sustainable development under the background of new urbanization. The research made a comprehensive analysis on land uses in Yunnan under ...Scientific analysis and determination of land use lays foundation for regional sustainable development under the background of new urbanization. The research made a comprehensive analysis on land uses in Yunnan under the background of urbanization and proposed strategies for further development, providing references for land uses scientific decision making.展开更多
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a significant human pathogen that results in mucocutaneous lesions in the oral cavity or genital infections. Acyclovir (ACV) and related nucleos...Herpes simplex virus (HSV), a member of the Herpesviridae family, is a significant human pathogen that results in mucocutaneous lesions in the oral cavity or genital infections. Acyclovir (ACV) and related nucleoside analogues can successfully treat HSV infections, but the emergence of drug resistance to ACV has created a barrier for the treatment of HSV infections, especially in immunocompromised patients. There is an urgent need to explore new and effective tactics to circumvent drug resistance to HSV. This review summarises the current strategies in the development of new targets (the DNA helicase/primase (H/P) complex), new types of molecules (nature products) and new antiviral mechanisms (lethal mutagenesis of Janus-type nucleosides) to fight the drug resistance of HSV.展开更多
Since the end of the Cold War, the non-proliferation work on Weapons of Mass Destruction (WMD) has gradually become the first priority in the field of arms control and international security. With the unswerving effor...Since the end of the Cold War, the non-proliferation work on Weapons of Mass Destruction (WMD) has gradually become the first priority in the field of arms control and international security. With the unswerving efforts by international community, enormous progress has been made in the construction .展开更多
BACKGROUND Cervical cancer is the second leading cause of death in women worldwide,second only to breast cancer.Around 80%of women have been infected with human papillomavirus(HPV)in their lifetime.Early screening and...BACKGROUND Cervical cancer is the second leading cause of death in women worldwide,second only to breast cancer.Around 80%of women have been infected with human papillomavirus(HPV)in their lifetime.Early screening and treatment are effective means of preventing cervical cancer,but due to economic reasons,many parts of the world do not have free screening programs to protect women’s health.AIM To increase HPV cervical cancer screening in Changsha and reduce the incidence of cervical cancer.METHODS Cervical cancer screening included gynecological examination,vaginal secretion examination and HPV high-risk typing testing.Cervical cytology examination(ThinPrep cytology test)was performed for individuals who test positive for HPV types other than 16 and 18.Vaginal colposcopy examination was performed for HPV16 and 18 positive individuals,as well as for those who were positive for ThinPrep cytology test.If the results of vaginal colposcopy examination were abnormal,histopathological examination was performed.We conducted a cost-benefit analysis after 4 years.RESULTS From 2019 to 2022,523437 women aged 35-64 years in Changsha city were screened and 73313 were positive,with a 14%positive rate.The detection rate of precancerous lesions of cervical cancer was 0.6%and the detection rate of cervical cancer was 0.037%.Among 311212 patients who underwent two cancers examinations,the incidence rate was reduced by more than half in the second examination.The average screening cost per woman was 120 RMB.The average cost of detecting early cases was 10619 RMB,with an early detection cost coefficient of 0.083.CONCLUSION Our screening strategy was effective and cost-effective,making it valuable for early diagnosis and treatment of cervical cancer.It is worth promoting in economically limited areas.展开更多
Objective:To develop new therapeutic strategies for diabetes mellitus(DM)by analyzing the mechanisms of action of traditional Chinese medicine(TCM)'xiaoke'formulae(TCM prescriptions for remedying xiaoke).Metho...Objective:To develop new therapeutic strategies for diabetes mellitus(DM)by analyzing the mechanisms of action of traditional Chinese medicine(TCM)'xiaoke'formulae(TCM prescriptions for remedying xiaoke).Methods:We characterized 291 xiaoke formulae,including the herbs contained,chemical composition,constituents'targets,and corresponding genes.Xiaoke-related genes were retrieved based on the relationships of constituents'targets and xiaoke formulae,and a threshold of over 95.88%occurrence of each constituent target in the 291 TCM formulae served as a definition for xiaoke-related genes.Upon comparison with DM-related genes in the DisGeNET database,the genes differing in expression between cases administered TCM and synthetic drugs were explored using a TCM grammar system.Results:The results showed that xiaoke formulae and 14 exclusively xiaoke-related genes were significantly associated with multiple biological processes closely related to DM and diabetic complications(P<.01).Moreover,intervention in the expression of these xiaoke-related genes would affect DM-related genes directly or indirectly.Conclusion:The 14 xiaoke-related genes APEX1,EHMT2,TSHR,CBX1,FEN1,GMNN,JUN,KMT2A,MAPT,POLl,USP1,PIN1,POLB,and POLK can serve as candidate genes for antidiabetic drug design.Compared with DM-related genes in DisGeNET,intervention in the expression of 14 xiaoke-related genes by TCM formulae has the potential to not only lower blood glucose,but also reduce the occurrence of some side effects and inhibit the development of diabetic complications.These findings will contribute to the discovery of new strategies for treating DM.展开更多
Starting from the historical evolution of China s regional coordinated development policy and practice,three stages of"enlightenment stage","development stage"and"maturity stage",as well ...Starting from the historical evolution of China s regional coordinated development policy and practice,three stages of"enlightenment stage","development stage"and"maturity stage",as well as the connotation,characteristics and content of implementing regional coordinated development strategy were analyzed.On this basis,from different aspects of industrial distribution,pollutant characteristics and regional environmental protection policy,the existing ecological and environmental protection problems in China s regional coordinated development in the new era were analyzed,and some suggestions for the next step were put forward.It is necessary to follow the"four ones"concept from the overall point of view,implement"three lines and one list"from the perspective of the width of the access red line,strengthen"joint prevention and control"from the perspective of the depth of regional regulation,deepen the"planning environmental impact assessment"from the perspective of the breadth of industrial distribution,and promote the"green-way model"from the perspective of ecological low carbon.展开更多
With the multiple clues, rambling narrative and multidimensional architecture, Jones, in The Known World, constructs a fairly layered, three-dimensional world and presents a panorama of the entire slave society. The s...With the multiple clues, rambling narrative and multidimensional architecture, Jones, in The Known World, constructs a fairly layered, three-dimensional world and presents a panorama of the entire slave society. The so-called mongline History before is decomposed into a number of linear histories, and history which was non-narrative and non-representational is dismantled into histories narrated by many single narrators. Cultural discourse and historical discourse blend together. Jones shares the same conception on history and literature with New Historical critics who emphasize the complex mix-and-match interaction between history and text.展开更多
In responding to the“dual carbon”strategy,intelligent networked new energy vehicle technology plays a crucial role.This type of vehicle combines the advantages of new energy technology and intelligent network techno...In responding to the“dual carbon”strategy,intelligent networked new energy vehicle technology plays a crucial role.This type of vehicle combines the advantages of new energy technology and intelligent network technology,effectively reduces carbon emissions in the transportation sector,improves energy utilization efficiency,and contributes to the green transportation system through intelligent transportation management and collaborative work between vehicles,making significant contributions.This article aims to explore the development of intelligent network-connected new energy vehicle technology and applications under the dual-carbon strategy and lay the foundation for the future development direction of the automotive industry.展开更多
Modularity can simplify the process of complex product design and manufacture effectively,and it can also optimize the supply resource to satisfy the customization needs of customers,which has aroused more and more aw...Modularity can simplify the process of complex product design and manufacture effectively,and it can also optimize the supply resource to satisfy the customization needs of customers,which has aroused more and more awareness of people both in management theory research and in enterprise practice recently.In the article,we analyze the difficulty of complex product manufacture,introduce the idea of modular manufacture and research the basic content of modular manufacture strategy.Meanwhile,the significance of modular manufacture strategy to build up core competition and fast innovation for the manufacture industry are studied.At last,we discuss the necessity of building modular manufacture strategy and its modes and process.The studies demonstrate that based on modular manufacture is crucial to establish enterprise strategy and optimize enterprise competence.展开更多
Through investigating current sea use in coastal cities of China,and exploring foreign and domestic researches on sea use,this paper took Binhai New Area of Tianjin City for example to analyze major problems of its se...Through investigating current sea use in coastal cities of China,and exploring foreign and domestic researches on sea use,this paper took Binhai New Area of Tianjin City for example to analyze major problems of its sea use in ecological security,planar form,land use layout,specialized planning,management and regulatory mechanism,then proposed strategies from 4 perspectives,namely ecological conservation and restoration,optimization of planning planar form,optimization of planning land use layout,and planning management,in order to provide references and instructions for the sea use planning of Chinese coastal cities.展开更多
Two years have past since September 11 events. Then to what extent has the U. S. global strategy changed? This is still a question in dispute. From the actions taken by U. S. A. and the various American documents publ...Two years have past since September 11 events. Then to what extent has the U. S. global strategy changed? This is still a question in dispute. From the actions taken by U. S. A. and the various American documents published in the past two years, we can find that there have been no much changes in U. S. global strategic objectives. The essence of the disputes over "New Empire" in U. S. A. is how to maintain U. S. hegemonic position as long as possible. Although the pattern展开更多
Cotton bollworm(He1icoverpa armigera)is an important agricultural pest that causes severe yield loss to crops,particularly to cotton.Transgenic Bt crops have been successful in protecting plant s,however,Bt proteins a...Cotton bollworm(He1icoverpa armigera)is an important agricultural pest that causes severe yield loss to crops,particularly to cotton.Transgenic Bt crops have been successful in protecting plant s,however,Bt proteins are to xic to all lepidopteran insects but have little effects to sucking pests,such as aphids.Furthermore,the continuo us use of Bt crop s increases insect resistance.These call for new transgenic app roac hes of pest control.The bollworms have adapted to cotto n plants,de-spite that most cotton cultivars accumulate a high level of gossypol and related sesquiterpene p hytoa-lexins.展开更多
From 1999, with the rapid expansion of enrollment scale, colleges have experienced fast development and construction of new campuses. However, the urgency of the demand for campus space at that time led to the shortco...From 1999, with the rapid expansion of enrollment scale, colleges have experienced fast development and construction of new campuses. However, the urgency of the demand for campus space at that time led to the shortcomings of paying more attention to speed than connotation during the construction of the new campus. Even now the evaluation of new campuses which have been used for nearly twenty years and whether the space of new campuses has played its due role will affect the display of the heritage and temperament of colleges. This paper uses the typical spatial cognitive concept—spatial image to analyse the elements of spatial images on campuses, summarizes the perceptions of teachers and students towards the space of four new campuses in Chengdu through questionnaire survey and analysis, puts forward the principles of campus space design and the strategies of classification design, and intends to take spatial images as the research cut-in point to provide new ideas and suggestions for the design and improvement of campus space from the perspective of users.展开更多
From a strategic perspective,the paper presents a forward-looking thinking supported by interdisciplinary of modern logistics,estuary and coast,environment and ecology,economic management and mathematical statistics. ...From a strategic perspective,the paper presents a forward-looking thinking supported by interdisciplinary of modern logistics,estuary and coast,environment and ecology,economic management and mathematical statistics. It leads to a reasonable solution to space expansion by reclamation. Construction of new deepwater terminal is the best usage of land resources and can strengthen the status of Shanghai as an international shipping center,thus support the preparation and strategic decision of future urban development of Shanghai.展开更多
Fumin County is a satellite town closest to Kunming City,its economic development level has lagged behind that of the city and other districts and counties of the city,and the urbanization rate has been quite low.Thro...Fumin County is a satellite town closest to Kunming City,its economic development level has lagged behind that of the city and other districts and counties of the city,and the urbanization rate has been quite low.Through analyzing development conditions and problems of Fumin County,strategies and countermeasures were put forward for the new urbanization of the county during the Fourteenth Five-year Plan.展开更多
This paper reviews a strategic scientific proposal to dig and construct three navigable sea lanes linking isolated inland seas and blocked side bays and linking it with the open seas, to facilitate the movement of fre...This paper reviews a strategic scientific proposal to dig and construct three navigable sea lanes linking isolated inland seas and blocked side bays and linking it with the open seas, to facilitate the movement of free trade and international navigation, and to break the captivity of geographically isolated environments, and to give a strategic advantage to some areas and sectors that are neglected politically, socially, economically and environmentally, and to adopt the strategy of establishing a marine channel between the “Caspian Sea” and the “Black Sea” through the “lands belonging to Russia”. On digging a navigational canal at the lowest cost in a plain area within the territory of Russia, with a length of approximately 600 kilometers (616 km), starting from the nearest bay in the Caspian Sea, passing near the city of “Pyatigorsk” to the city of “Sochi” on the Black Sea, while it comes: -The strategy of the waterway and the sea channel between the “Caspian Sea” and the “Arabian Gulf” through the “lands belonging to Iran” by digging and cutting a path in the rocks with a width of 100 meters and a length of about 700 kilometers, and at a time rate of less than 10 years, and this project will liberate all countries in the Caspian Sea, and the study concludes with the strategy of the navigational channel between the “Arabian Gulf” and the “Mediterranean Sea” through the two countries of “Iraq-Syria”, with a length of about 1350 km, and the world will benefit in the security, commercial and political fields.展开更多
In a new round of urban renewal,China’s urban space expansion is shifting from incremental development to inventory mining.Residents’ demands for improvement of community material environment and community cultural ...In a new round of urban renewal,China’s urban space expansion is shifting from incremental development to inventory mining.Residents’ demands for improvement of community material environment and community cultural identity are increasing.Meantime,affected by the COVID-19 pandemic in 2019,community resilience has become an urgent problem to be solved in urban communities.Based on resilience theory,TOD theory and other planning concepts,the paper analyzes the vulnerability of Shanghai Caoyang river ring area,and puts forward a multi-level community resilience improvement strategy,including increasing diversified public service facilities,building public pedestrian network,and reshaping public open space to improve the stability,adaptability and resilience of the community,in order to build the development path of resilient communities.The study will provide inspiration for future micro-renewal of communities and promote the sustainable development of urban communities.展开更多
Regeneration in the central nervous system (CNS) is limited, and CNS damage often leads to cognitive impairment or permanent functional motor and sensory loss. Impaired regenerative capacity is multifactorial and in...Regeneration in the central nervous system (CNS) is limited, and CNS damage often leads to cognitive impairment or permanent functional motor and sensory loss. Impaired regenerative capacity is multifactorial and includes inflammation, loss of the blood-brain barrier, and alteration in the extracellular matrix (ECM). One of the main problems is the formation of a glial scar and the production of inhibitory ECM, such as proteoglycans, that generates a physical and mechanical barrier, impeding axonal regrowth (Figure 1A).展开更多
The paper mainly studies a new way of combining American culture with English language teaching and learning by means of the VOA Special English feature programs. It is based on a 5-year period of teaching practice, e...The paper mainly studies a new way of combining American culture with English language teaching and learning by means of the VOA Special English feature programs. It is based on a 5-year period of teaching practice, experience and reflection. This interactive, innovative, productive and student-centered approach is a far cry from the rigid, old, unproductive and teacher-centered approach of teaching British and American culture without combining language learning and practice as is commonly used here in Chinese colleges. The author also throws some light on how to use on-line teaching resources and how to cultivate independent learning on the part of the students he has worked with.展开更多
With the deepening of curriculum reform in junior high school,the education field is undergoing tremendous changes.Besides,with the rapid development of the Internet today,students have been exposed to various new med...With the deepening of curriculum reform in junior high school,the education field is undergoing tremendous changes.Besides,with the rapid development of the Internet today,students have been exposed to various new media software since childhood.The existing education and teaching are also desperately keeping up with the pace of the times,and continue to bring online teaching to the practical classrooms of rural middle schools through new media.Teachers should not only impart basic professional knowledge to students,but also improve students'ability to use English.展开更多
基金Supported by Science Research Foundation of the Education Department of Yunnan Province(2014J089)~~
文摘Scientific analysis and determination of land use lays foundation for regional sustainable development under the background of new urbanization. The research made a comprehensive analysis on land uses in Yunnan under the background of urbanization and proposed strategies for further development, providing references for land uses scientific decision making.
基金the National Natural Science Foundations of China(document no.:81321002,81500860,81300888)a grant from 111 Project of Ministry of Education,China,for fi nancial support
文摘Herpes simplex virus (HSV), a member of the Herpesviridae family, is a significant human pathogen that results in mucocutaneous lesions in the oral cavity or genital infections. Acyclovir (ACV) and related nucleoside analogues can successfully treat HSV infections, but the emergence of drug resistance to ACV has created a barrier for the treatment of HSV infections, especially in immunocompromised patients. There is an urgent need to explore new and effective tactics to circumvent drug resistance to HSV. This review summarises the current strategies in the development of new targets (the DNA helicase/primase (H/P) complex), new types of molecules (nature products) and new antiviral mechanisms (lethal mutagenesis of Janus-type nucleosides) to fight the drug resistance of HSV.
文摘Since the end of the Cold War, the non-proliferation work on Weapons of Mass Destruction (WMD) has gradually become the first priority in the field of arms control and international security. With the unswerving efforts by international community, enormous progress has been made in the construction .
文摘BACKGROUND Cervical cancer is the second leading cause of death in women worldwide,second only to breast cancer.Around 80%of women have been infected with human papillomavirus(HPV)in their lifetime.Early screening and treatment are effective means of preventing cervical cancer,but due to economic reasons,many parts of the world do not have free screening programs to protect women’s health.AIM To increase HPV cervical cancer screening in Changsha and reduce the incidence of cervical cancer.METHODS Cervical cancer screening included gynecological examination,vaginal secretion examination and HPV high-risk typing testing.Cervical cytology examination(ThinPrep cytology test)was performed for individuals who test positive for HPV types other than 16 and 18.Vaginal colposcopy examination was performed for HPV16 and 18 positive individuals,as well as for those who were positive for ThinPrep cytology test.If the results of vaginal colposcopy examination were abnormal,histopathological examination was performed.We conducted a cost-benefit analysis after 4 years.RESULTS From 2019 to 2022,523437 women aged 35-64 years in Changsha city were screened and 73313 were positive,with a 14%positive rate.The detection rate of precancerous lesions of cervical cancer was 0.6%and the detection rate of cervical cancer was 0.037%.Among 311212 patients who underwent two cancers examinations,the incidence rate was reduced by more than half in the second examination.The average screening cost per woman was 120 RMB.The average cost of detecting early cases was 10619 RMB,with an early detection cost coefficient of 0.083.CONCLUSION Our screening strategy was effective and cost-effective,making it valuable for early diagnosis and treatment of cervical cancer.It is worth promoting in economically limited areas.
基金the National Natural Science Foundation of China(81673697 and 81373985).
文摘Objective:To develop new therapeutic strategies for diabetes mellitus(DM)by analyzing the mechanisms of action of traditional Chinese medicine(TCM)'xiaoke'formulae(TCM prescriptions for remedying xiaoke).Methods:We characterized 291 xiaoke formulae,including the herbs contained,chemical composition,constituents'targets,and corresponding genes.Xiaoke-related genes were retrieved based on the relationships of constituents'targets and xiaoke formulae,and a threshold of over 95.88%occurrence of each constituent target in the 291 TCM formulae served as a definition for xiaoke-related genes.Upon comparison with DM-related genes in the DisGeNET database,the genes differing in expression between cases administered TCM and synthetic drugs were explored using a TCM grammar system.Results:The results showed that xiaoke formulae and 14 exclusively xiaoke-related genes were significantly associated with multiple biological processes closely related to DM and diabetic complications(P<.01).Moreover,intervention in the expression of these xiaoke-related genes would affect DM-related genes directly or indirectly.Conclusion:The 14 xiaoke-related genes APEX1,EHMT2,TSHR,CBX1,FEN1,GMNN,JUN,KMT2A,MAPT,POLl,USP1,PIN1,POLB,and POLK can serve as candidate genes for antidiabetic drug design.Compared with DM-related genes in DisGeNET,intervention in the expression of 14 xiaoke-related genes by TCM formulae has the potential to not only lower blood glucose,but also reduce the occurrence of some side effects and inhibit the development of diabetic complications.These findings will contribute to the discovery of new strategies for treating DM.
基金Supported by Special Project for Prevention and Control of Air Pollution from Fixed Sources of Ministry of Ecology and Environment,China(2020A060).
文摘Starting from the historical evolution of China s regional coordinated development policy and practice,three stages of"enlightenment stage","development stage"and"maturity stage",as well as the connotation,characteristics and content of implementing regional coordinated development strategy were analyzed.On this basis,from different aspects of industrial distribution,pollutant characteristics and regional environmental protection policy,the existing ecological and environmental protection problems in China s regional coordinated development in the new era were analyzed,and some suggestions for the next step were put forward.It is necessary to follow the"four ones"concept from the overall point of view,implement"three lines and one list"from the perspective of the width of the access red line,strengthen"joint prevention and control"from the perspective of the depth of regional regulation,deepen the"planning environmental impact assessment"from the perspective of the breadth of industrial distribution,and promote the"green-way model"from the perspective of ecological low carbon.
文摘With the multiple clues, rambling narrative and multidimensional architecture, Jones, in The Known World, constructs a fairly layered, three-dimensional world and presents a panorama of the entire slave society. The so-called mongline History before is decomposed into a number of linear histories, and history which was non-narrative and non-representational is dismantled into histories narrated by many single narrators. Cultural discourse and historical discourse blend together. Jones shares the same conception on history and literature with New Historical critics who emphasize the complex mix-and-match interaction between history and text.
文摘In responding to the“dual carbon”strategy,intelligent networked new energy vehicle technology plays a crucial role.This type of vehicle combines the advantages of new energy technology and intelligent network technology,effectively reduces carbon emissions in the transportation sector,improves energy utilization efficiency,and contributes to the green transportation system through intelligent transportation management and collaborative work between vehicles,making significant contributions.This article aims to explore the development of intelligent network-connected new energy vehicle technology and applications under the dual-carbon strategy and lay the foundation for the future development direction of the automotive industry.
文摘Modularity can simplify the process of complex product design and manufacture effectively,and it can also optimize the supply resource to satisfy the customization needs of customers,which has aroused more and more awareness of people both in management theory research and in enterprise practice recently.In the article,we analyze the difficulty of complex product manufacture,introduce the idea of modular manufacture and research the basic content of modular manufacture strategy.Meanwhile,the significance of modular manufacture strategy to build up core competition and fast innovation for the manufacture industry are studied.At last,we discuss the necessity of building modular manufacture strategy and its modes and process.The studies demonstrate that based on modular manufacture is crucial to establish enterprise strategy and optimize enterprise competence.
基金Sponsored by Natural Science Foundation of Tianjin City(11JCYBJC02800)Key Program of National Social Science Foundation of China(13&ZD162)
文摘Through investigating current sea use in coastal cities of China,and exploring foreign and domestic researches on sea use,this paper took Binhai New Area of Tianjin City for example to analyze major problems of its sea use in ecological security,planar form,land use layout,specialized planning,management and regulatory mechanism,then proposed strategies from 4 perspectives,namely ecological conservation and restoration,optimization of planning planar form,optimization of planning land use layout,and planning management,in order to provide references and instructions for the sea use planning of Chinese coastal cities.
文摘Two years have past since September 11 events. Then to what extent has the U. S. global strategy changed? This is still a question in dispute. From the actions taken by U. S. A. and the various American documents published in the past two years, we can find that there have been no much changes in U. S. global strategic objectives. The essence of the disputes over "New Empire" in U. S. A. is how to maintain U. S. hegemonic position as long as possible. Although the pattern
文摘Cotton bollworm(He1icoverpa armigera)is an important agricultural pest that causes severe yield loss to crops,particularly to cotton.Transgenic Bt crops have been successful in protecting plant s,however,Bt proteins are to xic to all lepidopteran insects but have little effects to sucking pests,such as aphids.Furthermore,the continuo us use of Bt crop s increases insect resistance.These call for new transgenic app roac hes of pest control.The bollworms have adapted to cotto n plants,de-spite that most cotton cultivars accumulate a high level of gossypol and related sesquiterpene p hytoa-lexins.
基金Sponsored by Technology Research Program of Sichuan Province of China(2016JY0111)
文摘From 1999, with the rapid expansion of enrollment scale, colleges have experienced fast development and construction of new campuses. However, the urgency of the demand for campus space at that time led to the shortcomings of paying more attention to speed than connotation during the construction of the new campus. Even now the evaluation of new campuses which have been used for nearly twenty years and whether the space of new campuses has played its due role will affect the display of the heritage and temperament of colleges. This paper uses the typical spatial cognitive concept—spatial image to analyse the elements of spatial images on campuses, summarizes the perceptions of teachers and students towards the space of four new campuses in Chengdu through questionnaire survey and analysis, puts forward the principles of campus space design and the strategies of classification design, and intends to take spatial images as the research cut-in point to provide new ideas and suggestions for the design and improvement of campus space from the perspective of users.
基金Shanghai Science and Technology Research Plan(No.13dz1204900)
文摘From a strategic perspective,the paper presents a forward-looking thinking supported by interdisciplinary of modern logistics,estuary and coast,environment and ecology,economic management and mathematical statistics. It leads to a reasonable solution to space expansion by reclamation. Construction of new deepwater terminal is the best usage of land resources and can strengthen the status of Shanghai as an international shipping center,thus support the preparation and strategic decision of future urban development of Shanghai.
基金Supported by Scientific Research Fund Project of Education Department of Yunan Province(2022J0483)。
文摘Fumin County is a satellite town closest to Kunming City,its economic development level has lagged behind that of the city and other districts and counties of the city,and the urbanization rate has been quite low.Through analyzing development conditions and problems of Fumin County,strategies and countermeasures were put forward for the new urbanization of the county during the Fourteenth Five-year Plan.
文摘This paper reviews a strategic scientific proposal to dig and construct three navigable sea lanes linking isolated inland seas and blocked side bays and linking it with the open seas, to facilitate the movement of free trade and international navigation, and to break the captivity of geographically isolated environments, and to give a strategic advantage to some areas and sectors that are neglected politically, socially, economically and environmentally, and to adopt the strategy of establishing a marine channel between the “Caspian Sea” and the “Black Sea” through the “lands belonging to Russia”. On digging a navigational canal at the lowest cost in a plain area within the territory of Russia, with a length of approximately 600 kilometers (616 km), starting from the nearest bay in the Caspian Sea, passing near the city of “Pyatigorsk” to the city of “Sochi” on the Black Sea, while it comes: -The strategy of the waterway and the sea channel between the “Caspian Sea” and the “Arabian Gulf” through the “lands belonging to Iran” by digging and cutting a path in the rocks with a width of 100 meters and a length of about 700 kilometers, and at a time rate of less than 10 years, and this project will liberate all countries in the Caspian Sea, and the study concludes with the strategy of the navigational channel between the “Arabian Gulf” and the “Mediterranean Sea” through the two countries of “Iraq-Syria”, with a length of about 1350 km, and the world will benefit in the security, commercial and political fields.
基金Sponsored by Social Science Foundation of Hebei Province (HB19YS039)。
文摘In a new round of urban renewal,China’s urban space expansion is shifting from incremental development to inventory mining.Residents’ demands for improvement of community material environment and community cultural identity are increasing.Meantime,affected by the COVID-19 pandemic in 2019,community resilience has become an urgent problem to be solved in urban communities.Based on resilience theory,TOD theory and other planning concepts,the paper analyzes the vulnerability of Shanghai Caoyang river ring area,and puts forward a multi-level community resilience improvement strategy,including increasing diversified public service facilities,building public pedestrian network,and reshaping public open space to improve the stability,adaptability and resilience of the community,in order to build the development path of resilient communities.The study will provide inspiration for future micro-renewal of communities and promote the sustainable development of urban communities.
文摘Regeneration in the central nervous system (CNS) is limited, and CNS damage often leads to cognitive impairment or permanent functional motor and sensory loss. Impaired regenerative capacity is multifactorial and includes inflammation, loss of the blood-brain barrier, and alteration in the extracellular matrix (ECM). One of the main problems is the formation of a glial scar and the production of inhibitory ECM, such as proteoglycans, that generates a physical and mechanical barrier, impeding axonal regrowth (Figure 1A).
文摘The paper mainly studies a new way of combining American culture with English language teaching and learning by means of the VOA Special English feature programs. It is based on a 5-year period of teaching practice, experience and reflection. This interactive, innovative, productive and student-centered approach is a far cry from the rigid, old, unproductive and teacher-centered approach of teaching British and American culture without combining language learning and practice as is commonly used here in Chinese colleges. The author also throws some light on how to use on-line teaching resources and how to cultivate independent learning on the part of the students he has worked with.
基金Supported by Provincial College Students'Innovation and Entrepreneurship Training Program Project of Education Department of Sichuan Province in 2021"A Method of Memorizing Foreign Languages Faster Based on Solving Students'Foreign Language Learning Problems"(S202114389129).
文摘With the deepening of curriculum reform in junior high school,the education field is undergoing tremendous changes.Besides,with the rapid development of the Internet today,students have been exposed to various new media software since childhood.The existing education and teaching are also desperately keeping up with the pace of the times,and continue to bring online teaching to the practical classrooms of rural middle schools through new media.Teachers should not only impart basic professional knowledge to students,but also improve students'ability to use English.