Objective To observe the clinical effect of acupuncture at Neiguan （内关 PC 6） in combination with respiratory reinforcing and reducing method for treatment of cardiac neurosis. Methods Thirty-eight patients with ca...Objective To observe the clinical effect of acupuncture at Neiguan （内关 PC 6） in combination with respiratory reinforcing and reducing method for treatment of cardiac neurosis. Methods Thirty-eight patients with cardiac neurosis were selected for treatment through acupuncture at PC 6 in combination with respiratory reinforcing and reducing method. With twice per day, treated for 6 days per week, and 4 weeks as one course, the therapeutic effect was assessed after one course. Results Twenty-one cases were cured, 15 cases were remarkably improved, and 2 cases were failed. The total effective rate was 94.7%. Conclusion Acupuncture at PC 6 in combination with respiratory reinforcing and reducing method is effective in treatment of cardiac neurosis.展开更多
In this study, there were 62 patients with depressive neurosis. AInong them, 31 caseswere treated by laseracupuncture, another 31 cases were treated by pharmacotherapy, such as Antide-pressants and Antianxietics. The ...In this study, there were 62 patients with depressive neurosis. AInong them, 31 caseswere treated by laseracupuncture, another 31 cases were treated by pharmacotherapy, such as Antide-pressants and Antianxietics. The course of treatment for each case was 21 days. The therapeutic ef-fects, which were comprehensively evaluated with Hamilton’s Depression Scale (HAMD) and Hamil-ton’s Anxiety Scale (HAMI) as well as Clinical Global Impression Scale (CGI) in combination withtraditional evaluation of clinical therapeutic effect, indicated that treating the depressive neurosis withlaser-acupuncture can obtain sound effects with a clinical effective rate of 90. 32 percent, markedly ef-fective rate of 67. 74 percent. The global scores of Hamilton’s Depression Scale and Hamilton’s Anxi-ety scale after treatment were obviously less than those before treatment (P【0.001 ), similar to theeffects of pharmacotherapy or even much better than those in pharmacotherapy group in some aspects.Treating with laser-acupuncture展开更多
77 cases of neurosis were treated with intelligent(computerized)elec-troacupuncture(IEA)and common electroacupuncture(CEA)at two different wave forms and fre-quencies.The results showed that the markedly effective rat...77 cases of neurosis were treated with intelligent(computerized)elec-troacupuncture(IEA)and common electroacupuncture(CEA)at two different wave forms and fre-quencies.The results showed that the markedly effective rates of IEA and CEA were respectively75% and 60% without a statistically significant difference.For different subtypes of neurosis,thetherapeutic effects of IEC in the treatment 6f neurasthenia and depressive neurosis were superior toand in the treatment of anxiety was inferior to those of CEA.For different syndromes,the curativeeffects of IEA on somatic symptom,depression and asthenic symptom were.superior to and on anxietyand sleep-disorder were not as good as those of CEA.展开更多
Objective:To analyze the prescription and medication rule of traditional Chinese medicine(TCM)in treating cardiac neurosis by using the software of"Traditional Chinese Medicine Inheritance Assistant Platform(V2.5...Objective:To analyze the prescription and medication rule of traditional Chinese medicine(TCM)in treating cardiac neurosis by using the software of"Traditional Chinese Medicine Inheritance Assistant Platform(V2.5)".Methods:China Journal Full-Text Database,Wanfang database,Weipu Chinese Periodical Service Platform and Chinese biomedical literature database were retrieved according to the inclusion and exclusion criteria.Literatures on the treatment of cardiac neurosis with TCM prescriptions were screened out and data mining was carried out using the TCM inheritance assistant platform.Use frequency,commonly used dose,the frequency of properties,flavors and meridian distribution were counted.Association rules and entropy clustering analysis for complex system were used to extract core drug combinations and unsupervised entropy hierarchical clustering was used to predict potential new prescriptions.Results:Through literature retrieval and screening,210 types of prescriptions were finally selected,and 181 types of Chinese herbs were extracted,with cumulative frequency of 2410 times.Among them,there were 46 traditional Chinese medicines that were used more than 15 times.According to the efficacy and indication,they were classified into qi-regulating drugs,tranquilizers,qi-tonifying drugs,heat-clearing drugs,blood-tonifying drugs,etc.According to properties,flavors,and meridian distribution,warm and sweet drugs were the most commonly used,mostly distributing to the heart meridian,followed by liver and spleen meridians.Association rules showed that combination of radix paeoniae and paeonia-bupleurum was the most used;faructus aurantii and bupleurum had the strongest correlation,up to 90%.The network diagram indicated that bupleurum,angelica sinensis,radix paeoniae radix,and poria cocos were the core of the association network.Based on complex system entropy clustering,24 core drug combinations were obtained.The unsupervised entropy hierarchical clustering algorithm was used to extract 12 core drug combinations,and 6 potential new formulae were obtained by further clustering.Conclusion:Regulating qi and blood,addressing both symptoms and causes,and using purgation and tonification at the same time is the principle of the treatment of cardiac neuropathy with TCM.The treatment mainly starts from the heart,liver and spleen,and therapies include soothing the liver and regulating qi,clearing heat and resolving phlegm,tranquilizing and calming the nerves,and prompting blood circulation and diuresis.展开更多
Arguably, Africa comparatively remains a huge account for narratives within the context of repository of misery and violence in the 21 st-century, an attempt to political development has posed an irresistible challeng...Arguably, Africa comparatively remains a huge account for narratives within the context of repository of misery and violence in the 21 st-century, an attempt to political development has posed an irresistible challenge and a disturbing necessity for Mia Couto in Voices Made Night （1990） and Bessie Head in Tales of Tenderness and Power （1989）. The position of Couto as a white Mozambican writer and Head as an exiled coloured South African writer, living in her adopted country of Botswana, provides them with privileged neutrality from which to view the effect of the admixture of grinding poverty and violence as they ravage the landscapes of these countries. While Couto does not fail to incorporate the significance of power struggle between FRELIMO （Front for the Liberation of Mozambique） and RENAMO （Mozambique National Resistance） in the ~＇oices Made Night, Head＇s articulation of the complex manipulation of power becomes a resource for constructing a discourse of nationalism in Tales of Tenderness and Power. The paper intends to focus on the correlation between power and economic development in these anthologies. The paper will further examine how political power impacts on the socio-economic well being of the local folks in the Couto＇s Mozambique and Head＇s South Africa.展开更多
The treatment of cardiac neurosis in modern medicine lacks pertinence and its effectiveness is relatively unclear. Mongolian medicine dialectical treatment of cardiac neurosis can become a new research hotspot. Accord...The treatment of cardiac neurosis in modern medicine lacks pertinence and its effectiveness is relatively unclear. Mongolian medicine dialectical treatment of cardiac neurosis can become a new research hotspot. According to symptoms and pathogenesis, it can be classified as "palpitation". Mongolian medicine Shunqi Anshen Pills is made of 18 kinds of medicinal materials. It has the functions of warming nature, relieving pain, regulating viscosity, relieving Heyi and heat. It can be used for preventing and treating various diseases, especially for treating coronary heart disease, asymptomatic myocardial ischemia, angina pectoris, palpitation, arrhythmia, climacteric syndrome, insomnia and the like. It is a representative Mongolian prescription with a long history of clinical use. The therapeutic effect of Shunqi Anshen Pills on this disease is expected to be helpful for the optimization of clinical treatment measures.展开更多
2005284 Efficacy of venlafaxine on non-responders with major depressive disorder to selective serotonin reuptake inhibitors. YUAN Yong-gui (袁勇贵), et al. Dept Psychi, Affili Brain Hosp, Nanjing, Med limy, Nanjing 21...2005284 Efficacy of venlafaxine on non-responders with major depressive disorder to selective serotonin reuptake inhibitors. YUAN Yong-gui (袁勇贵), et al. Dept Psychi, Affili Brain Hosp, Nanjing, Med limy, Nanjing 210029. Chin J Psychi,2005;38(1):27-29. Objective: To assess the efficacy of venlafaxine in outpatients who did not respond to selective serotonin reuptake inhibitors (SSRI) treatment. Meth-展开更多
2009265 Non-invasive MR perfusion study in patients with depression.LU Su(吕粟),et al.Huaxi MR Research Center,Dept Radiol,West China Hsop,Chengdu 610041.Chin J Radiol,2009;43(3):244-248.
2010385 Regional homogeneity of hippocampus of major depressed patients before and after clinical recovery. WANG Li(王丽),et al. Nanjing Brain Hosp,Nanjing Med Univ,Nanjing. 210029. Chin J Nerv Ment Dis 2010;36(5):26...2010385 Regional homogeneity of hippocampus of major depressed patients before and after clinical recovery. WANG Li(王丽),et al. Nanjing Brain Hosp,Nanjing Med Univ,Nanjing. 210029. Chin J Nerv Ment Dis 2010;36(5):264-267. Objective The present study were to use fMRI to investigate the characteristics of the hippocampal activities of heavy depressed展开更多
2008490 Anxiety disease: decreased functional connectivity in left superior temporal gyrus (GTs) and right GTs. ZHAO Xiaohu(赵小虎), et al.Dept, Tongji Hosp, Tongji Univ, Shanghai 200065. Natl Med J China 2008;88(23):...2008490 Anxiety disease: decreased functional connectivity in left superior temporal gyrus (GTs) and right GTs. ZHAO Xiaohu(赵小虎), et al.Dept, Tongji Hosp, Tongji Univ, Shanghai 200065. Natl Med J China 2008;88(23):1603-1606. Objective To explore the characteristic of functional connectivity in anxiety disorders patient and the neural mechanism of this disease. This work was selected as an oral presentation in 2006 ISMRM.展开更多
目的:探索炎性因子与焦虑症之间潜在的因果关系,并以此为基础探究针灸治疗焦虑症的机制及靶点。方法:本次孟德尔随机化研究使用了炎性因子和焦虑症的全基因组关联研究(Genome Wide Association Study,GWAS),根据预设的阈值提取与41种炎...目的:探索炎性因子与焦虑症之间潜在的因果关系,并以此为基础探究针灸治疗焦虑症的机制及靶点。方法:本次孟德尔随机化研究使用了炎性因子和焦虑症的全基因组关联研究(Genome Wide Association Study,GWAS),根据预设的阈值提取与41种炎性因子显著相关的独立遗传位点作为工具变量(IVs)。主要采用逆方差加权(IVW)法进行孟德尔随机化分析,根据效应指标优势比(OR)和95%置信区间(CI)评估结果。使用留一法、异质性检验、水平基因多效性检验来验证结果的稳定性和可靠性。以针灸疗法治疗焦虑症为研究方向,搜索近十年探讨患者及模型动物病理变化及作用机制的相关文献。结果:通过IVW分析发现白细胞介素(Interleukin,IL)–12–p70的P值为0.015(P<0.05),以及其OR值与置信区间结果(OR=1.091,95%CI:1.01~1.17)。留一法分析显示结果稳定,不存在对结果有强影响的IVs,且可以剔除异质性和水平基因多效性对因果效应估计产生的影响。通过搜索近十年的文献,共纳入22篇针灸相关文献。结论:经研究发现,IL–12–p70可以增加焦虑症的患病风险。针灸可能通过调控神经递质及下丘脑–垂体–肾上腺轴(Hypothalamic–Pituitary–Adrenal,HPA轴)进一步调控IL–12–p70水平,改善焦虑症状。而通过针灸调控组蛋白修饰、miRNA水平进一步调控IL–12–p70水平的方式,需要进一步的研究加以验证。展开更多
文摘Objective To observe the clinical effect of acupuncture at Neiguan （内关 PC 6） in combination with respiratory reinforcing and reducing method for treatment of cardiac neurosis. Methods Thirty-eight patients with cardiac neurosis were selected for treatment through acupuncture at PC 6 in combination with respiratory reinforcing and reducing method. With twice per day, treated for 6 days per week, and 4 weeks as one course, the therapeutic effect was assessed after one course. Results Twenty-one cases were cured, 15 cases were remarkably improved, and 2 cases were failed. The total effective rate was 94.7%. Conclusion Acupuncture at PC 6 in combination with respiratory reinforcing and reducing method is effective in treatment of cardiac neurosis.
文摘In this study, there were 62 patients with depressive neurosis. AInong them, 31 caseswere treated by laseracupuncture, another 31 cases were treated by pharmacotherapy, such as Antide-pressants and Antianxietics. The course of treatment for each case was 21 days. The therapeutic ef-fects, which were comprehensively evaluated with Hamilton’s Depression Scale (HAMD) and Hamil-ton’s Anxiety Scale (HAMI) as well as Clinical Global Impression Scale (CGI) in combination withtraditional evaluation of clinical therapeutic effect, indicated that treating the depressive neurosis withlaser-acupuncture can obtain sound effects with a clinical effective rate of 90. 32 percent, markedly ef-fective rate of 67. 74 percent. The global scores of Hamilton’s Depression Scale and Hamilton’s Anxi-ety scale after treatment were obviously less than those before treatment (P【0.001 ), similar to theeffects of pharmacotherapy or even much better than those in pharmacotherapy group in some aspects.Treating with laser-acupuncture
文摘77 cases of neurosis were treated with intelligent(computerized)elec-troacupuncture(IEA)and common electroacupuncture(CEA)at two different wave forms and fre-quencies.The results showed that the markedly effective rates of IEA and CEA were respectively75% and 60% without a statistically significant difference.For different subtypes of neurosis,thetherapeutic effects of IEC in the treatment 6f neurasthenia and depressive neurosis were superior toand in the treatment of anxiety was inferior to those of CEA.For different syndromes,the curativeeffects of IEA on somatic symptom,depression and asthenic symptom were.superior to and on anxietyand sleep-disorder were not as good as those of CEA.
基金Natural Science Foundation of Beijing(No.7202126)Fund for Science and Technology Development of TCM in Beijing(No.JJ-2020-38)。
文摘Objective:To analyze the prescription and medication rule of traditional Chinese medicine(TCM)in treating cardiac neurosis by using the software of"Traditional Chinese Medicine Inheritance Assistant Platform(V2.5)".Methods:China Journal Full-Text Database,Wanfang database,Weipu Chinese Periodical Service Platform and Chinese biomedical literature database were retrieved according to the inclusion and exclusion criteria.Literatures on the treatment of cardiac neurosis with TCM prescriptions were screened out and data mining was carried out using the TCM inheritance assistant platform.Use frequency,commonly used dose,the frequency of properties,flavors and meridian distribution were counted.Association rules and entropy clustering analysis for complex system were used to extract core drug combinations and unsupervised entropy hierarchical clustering was used to predict potential new prescriptions.Results:Through literature retrieval and screening,210 types of prescriptions were finally selected,and 181 types of Chinese herbs were extracted,with cumulative frequency of 2410 times.Among them,there were 46 traditional Chinese medicines that were used more than 15 times.According to the efficacy and indication,they were classified into qi-regulating drugs,tranquilizers,qi-tonifying drugs,heat-clearing drugs,blood-tonifying drugs,etc.According to properties,flavors,and meridian distribution,warm and sweet drugs were the most commonly used,mostly distributing to the heart meridian,followed by liver and spleen meridians.Association rules showed that combination of radix paeoniae and paeonia-bupleurum was the most used;faructus aurantii and bupleurum had the strongest correlation,up to 90%.The network diagram indicated that bupleurum,angelica sinensis,radix paeoniae radix,and poria cocos were the core of the association network.Based on complex system entropy clustering,24 core drug combinations were obtained.The unsupervised entropy hierarchical clustering algorithm was used to extract 12 core drug combinations,and 6 potential new formulae were obtained by further clustering.Conclusion:Regulating qi and blood,addressing both symptoms and causes,and using purgation and tonification at the same time is the principle of the treatment of cardiac neuropathy with TCM.The treatment mainly starts from the heart,liver and spleen,and therapies include soothing the liver and regulating qi,clearing heat and resolving phlegm,tranquilizing and calming the nerves,and prompting blood circulation and diuresis.
文摘Arguably, Africa comparatively remains a huge account for narratives within the context of repository of misery and violence in the 21 st-century, an attempt to political development has posed an irresistible challenge and a disturbing necessity for Mia Couto in Voices Made Night （1990） and Bessie Head in Tales of Tenderness and Power （1989）. The position of Couto as a white Mozambican writer and Head as an exiled coloured South African writer, living in her adopted country of Botswana, provides them with privileged neutrality from which to view the effect of the admixture of grinding poverty and violence as they ravage the landscapes of these countries. While Couto does not fail to incorporate the significance of power struggle between FRELIMO （Front for the Liberation of Mozambique） and RENAMO （Mozambique National Resistance） in the ~＇oices Made Night, Head＇s articulation of the complex manipulation of power becomes a resource for constructing a discourse of nationalism in Tales of Tenderness and Power. The paper intends to focus on the correlation between power and economic development in these anthologies. The paper will further examine how political power impacts on the socio-economic well being of the local folks in the Couto＇s Mozambique and Head＇s South Africa.
文摘The treatment of cardiac neurosis in modern medicine lacks pertinence and its effectiveness is relatively unclear. Mongolian medicine dialectical treatment of cardiac neurosis can become a new research hotspot. According to symptoms and pathogenesis, it can be classified as "palpitation". Mongolian medicine Shunqi Anshen Pills is made of 18 kinds of medicinal materials. It has the functions of warming nature, relieving pain, regulating viscosity, relieving Heyi and heat. It can be used for preventing and treating various diseases, especially for treating coronary heart disease, asymptomatic myocardial ischemia, angina pectoris, palpitation, arrhythmia, climacteric syndrome, insomnia and the like. It is a representative Mongolian prescription with a long history of clinical use. The therapeutic effect of Shunqi Anshen Pills on this disease is expected to be helpful for the optimization of clinical treatment measures.
文摘2005284 Efficacy of venlafaxine on non-responders with major depressive disorder to selective serotonin reuptake inhibitors. YUAN Yong-gui (袁勇贵), et al. Dept Psychi, Affili Brain Hosp, Nanjing, Med limy, Nanjing 210029. Chin J Psychi,2005;38(1):27-29. Objective: To assess the efficacy of venlafaxine in outpatients who did not respond to selective serotonin reuptake inhibitors (SSRI) treatment. Meth-
文摘2009265 Non-invasive MR perfusion study in patients with depression.LU Su(吕粟),et al.Huaxi MR Research Center,Dept Radiol,West China Hsop,Chengdu 610041.Chin J Radiol,2009;43(3):244-248.
文摘2010385 Regional homogeneity of hippocampus of major depressed patients before and after clinical recovery. WANG Li(王丽),et al. Nanjing Brain Hosp,Nanjing Med Univ,Nanjing. 210029. Chin J Nerv Ment Dis 2010;36(5):264-267. Objective The present study were to use fMRI to investigate the characteristics of the hippocampal activities of heavy depressed
文摘2008490 Anxiety disease: decreased functional connectivity in left superior temporal gyrus (GTs) and right GTs. ZHAO Xiaohu(赵小虎), et al.Dept, Tongji Hosp, Tongji Univ, Shanghai 200065. Natl Med J China 2008;88(23):1603-1606. Objective To explore the characteristic of functional connectivity in anxiety disorders patient and the neural mechanism of this disease. This work was selected as an oral presentation in 2006 ISMRM.
文摘目的:探索炎性因子与焦虑症之间潜在的因果关系,并以此为基础探究针灸治疗焦虑症的机制及靶点。方法:本次孟德尔随机化研究使用了炎性因子和焦虑症的全基因组关联研究(Genome Wide Association Study,GWAS),根据预设的阈值提取与41种炎性因子显著相关的独立遗传位点作为工具变量(IVs)。主要采用逆方差加权(IVW)法进行孟德尔随机化分析,根据效应指标优势比(OR)和95%置信区间(CI)评估结果。使用留一法、异质性检验、水平基因多效性检验来验证结果的稳定性和可靠性。以针灸疗法治疗焦虑症为研究方向,搜索近十年探讨患者及模型动物病理变化及作用机制的相关文献。结果:通过IVW分析发现白细胞介素(Interleukin,IL)–12–p70的P值为0.015(P<0.05),以及其OR值与置信区间结果(OR=1.091,95%CI:1.01~1.17)。留一法分析显示结果稳定,不存在对结果有强影响的IVs,且可以剔除异质性和水平基因多效性对因果效应估计产生的影响。通过搜索近十年的文献,共纳入22篇针灸相关文献。结论:经研究发现,IL–12–p70可以增加焦虑症的患病风险。针灸可能通过调控神经递质及下丘脑–垂体–肾上腺轴(Hypothalamic–Pituitary–Adrenal,HPA轴)进一步调控IL–12–p70水平,改善焦虑症状。而通过针灸调控组蛋白修饰、miRNA水平进一步调控IL–12–p70水平的方式,需要进一步的研究加以验证。
