Objective:To evaluate the therapeutic efficacy of the umbilical acupuncture’s“Wind-Thunder Interaction Method”in treating schizophrenia(SCH)patients with liver stagnation and spleen deficiency.Methods:A total of 12...Objective:To evaluate the therapeutic efficacy of the umbilical acupuncture’s“Wind-Thunder Interaction Method”in treating schizophrenia(SCH)patients with liver stagnation and spleen deficiency.Methods:A total of 120 SCH patients with liver stagnation and spleen deficiency were selected and evenly divided by ball drawing.The umbilical acupuncture group received the“Wind-Thunder Interaction Method”,while the Western medicine group received pure Western medicine treatment.The outcomes were compared in terms of efficacy and other indicators.Results:The umbilical acupuncture group showed a higher total effective rate,a decrease in disease symptom scores,lower scores on the side effect rating scale,improved cognitive function scores,and excellent laboratory indicators,with p<0.05 between the groups.Conclusion:The“Wind-Thunder Interaction Method”of umbilical acupuncture demonstrated a relatively high effectiveness in treating SCH patients with liver stagnation and spleen deficiency,alleviating symptoms,reducing side effects,improving cognitive function,and facilitating the recovery of neuro-vascular regulatory peptide groups.展开更多
The development of scaffolds for repairing critical-sized bone defects heavily relies on establishing a neuro-vascularized network for proper penetration of nerves and blood vessels.Despite significant advancements in...The development of scaffolds for repairing critical-sized bone defects heavily relies on establishing a neuro-vascularized network for proper penetration of nerves and blood vessels.Despite significant advancements in using artificial bone-like scaffolds infused with various agents,challenges remain.Natural bone tissue consists of a porous bone matrix surrounded by a neuro-vascularized periosteum,with unique piezoelectric properties essential for bone growth.Drawing inspiration from this assembly,we developed a periosteum-bone-mimicking bilayer scaffold with piezoelectric properties for regeneration of critical-sized bone defects.The periosteum-like layer of this scaffold features a double network hydrogel composed of chelated alginate,gelatin methacrylate,and sintered whitlockite nanoparticles,emulating the viscoelastic and piezoelectric properties of the natural periosteum.The bone-like layer is composed of a porous structure of chitosan and bioactive hydroxyapatite created through a biomineralization process.Unlike conventional bone-like scaffolds,this bioinspired bilayer scaffold significantly enhances osteogenesis,angiogenesis,and neurogenesis combined with low-intensity pulsed ultrasound-assisted piezoelectric stimulation.Such a scheme enhances neuro-vascularized bone regeneration in vivo.The results suggest that the bilayer scaffold could serve as an effective self-powered electrical stimulator to expedite bone regeneration under dynamic physical stimulation.展开更多
Complications following supracondylar fracture of humerus are well-known. Pre- and post-operative complications have been documented in the literature. Neumvascular injury due to fracture fragments following this type...Complications following supracondylar fracture of humerus are well-known. Pre- and post-operative complications have been documented in the literature. Neumvascular injury due to fracture fragments following this type of fracture is described, latrogenic brachial artery during surgical treatment of this fracture is unknown to the literature. So we report a rare case of iatrogenic brachial artery injury during pinning of supracondylar fracture of humerus and try to create awareness to the surgeons that such injuries can occur with improper operative techniques.展开更多
文摘Objective:To evaluate the therapeutic efficacy of the umbilical acupuncture’s“Wind-Thunder Interaction Method”in treating schizophrenia(SCH)patients with liver stagnation and spleen deficiency.Methods:A total of 120 SCH patients with liver stagnation and spleen deficiency were selected and evenly divided by ball drawing.The umbilical acupuncture group received the“Wind-Thunder Interaction Method”,while the Western medicine group received pure Western medicine treatment.The outcomes were compared in terms of efficacy and other indicators.Results:The umbilical acupuncture group showed a higher total effective rate,a decrease in disease symptom scores,lower scores on the side effect rating scale,improved cognitive function scores,and excellent laboratory indicators,with p<0.05 between the groups.Conclusion:The“Wind-Thunder Interaction Method”of umbilical acupuncture demonstrated a relatively high effectiveness in treating SCH patients with liver stagnation and spleen deficiency,alleviating symptoms,reducing side effects,improving cognitive function,and facilitating the recovery of neuro-vascular regulatory peptide groups.
基金the National Natural Science Foundation of China(82325012)National Key Research and Development Program of China(2022YFC2405900,2022YFC2405901)+4 种基金China Postdoctoral Science Foundation(2024M754272)Natural Science Basic Research Program of Shaanxi(2024JC-YBQN-0804)Postdoctoral Research Fund of the Fourth Military Medical University(lj202220110)the Shaanxi Key Scientific and Technological Innovation Team(2020TD-033)by the Youth Innovation Team of Shaanxi Universities.
文摘The development of scaffolds for repairing critical-sized bone defects heavily relies on establishing a neuro-vascularized network for proper penetration of nerves and blood vessels.Despite significant advancements in using artificial bone-like scaffolds infused with various agents,challenges remain.Natural bone tissue consists of a porous bone matrix surrounded by a neuro-vascularized periosteum,with unique piezoelectric properties essential for bone growth.Drawing inspiration from this assembly,we developed a periosteum-bone-mimicking bilayer scaffold with piezoelectric properties for regeneration of critical-sized bone defects.The periosteum-like layer of this scaffold features a double network hydrogel composed of chelated alginate,gelatin methacrylate,and sintered whitlockite nanoparticles,emulating the viscoelastic and piezoelectric properties of the natural periosteum.The bone-like layer is composed of a porous structure of chitosan and bioactive hydroxyapatite created through a biomineralization process.Unlike conventional bone-like scaffolds,this bioinspired bilayer scaffold significantly enhances osteogenesis,angiogenesis,and neurogenesis combined with low-intensity pulsed ultrasound-assisted piezoelectric stimulation.Such a scheme enhances neuro-vascularized bone regeneration in vivo.The results suggest that the bilayer scaffold could serve as an effective self-powered electrical stimulator to expedite bone regeneration under dynamic physical stimulation.
文摘Complications following supracondylar fracture of humerus are well-known. Pre- and post-operative complications have been documented in the literature. Neumvascular injury due to fracture fragments following this type of fracture is described, latrogenic brachial artery during surgical treatment of this fracture is unknown to the literature. So we report a rare case of iatrogenic brachial artery injury during pinning of supracondylar fracture of humerus and try to create awareness to the surgeons that such injuries can occur with improper operative techniques.
