Ultrasound has long been an essential tool in nephrology,traditionally used for procedures like vascular access and kidney biopsies.Point-of-care ultrasonography(POCUS),a rapidly evolving bedside technology,is now gai...Ultrasound has long been an essential tool in nephrology,traditionally used for procedures like vascular access and kidney biopsies.Point-of-care ultrasonography(POCUS),a rapidly evolving bedside technology,is now gaining momentum in nephrology by providing real-time imaging to enhance physical examination findings.Unlike comprehensive radiology-performed ultrasound,POCUS focuses on specific clinical questions,providing immediate and actionable insights.This narrative review examines the philosophy behind POCUS,its expanding applications in nephrology,and its impact on patient care,including its role in diagnosing obstructive uropathy,guiding fluid management,and evaluating hemodynamics in cardiorenal syndrome.Additionally,the review addresses barriers to widespread adoption,such as the need for structured training,competency validation,and interdisciplinary cooperation.By integrating POCUS into routine practice,nephrologists can refine diagnostic accuracy,improve patient outcomes,and strengthen the role of bedside medicine.展开更多
Point-of-care ultrasound(POCUS)is a limited ultrasound examination performed by the clinician at the bedside,emerging as a complement to physical examination across various medical specialties.In the field of nephrolo...Point-of-care ultrasound(POCUS)is a limited ultrasound examination performed by the clinician at the bedside,emerging as a complement to physical examination across various medical specialties.In the field of nephrology,its integration has been gradual,primarily limited to guiding procedures like temporary dialysis catheter placement or,in some cases,diagnostic kidney ultrasounds.In reality,the assessment of hemodynamic status at the bedside holds immense value for nephrologists,yet there exists limited awareness among practitioners regarding its implementation.While there is a growing trend towards incorporating multiorgan POCUS training in fellowship programs,private practice nephrologists remain relatively uninformed.This discussion explores the untapped potential of POCUS as a valuable diagnostic tool in everyday nephrology practice,demonstrating its effectiveness in diverse clinical settings,ranging from medical wards to outpatient dialysis units.Additionally,we delve into the challenges hindering its widespread adoption and consider the future trajectory of this innovative approach.展开更多
Objective: Chronic end-stage renal failure is a major public health problem in developing countries and is poorly documented. The objective of this study was to describe the epidemiological, diagnostic, therapeutic, a...Objective: Chronic end-stage renal failure is a major public health problem in developing countries and is poorly documented. The objective of this study was to describe the epidemiological, diagnostic, therapeutic, and evolutionary aspects of patients admitted for end-stage renal failure to the Department of Nephrology at the University Hospital of Brazzaville. Patients and Methods: This was a descriptive cross-sectional study collecting prospective data that took place over 10 months. We included 128 patients who were exhaustively identified. Sociodemographic, clinical, therapeutic and developmental data were collected using a standardized and pretested pre-established survey form. The EPI info software enabled the analysis and processing of the data. Results: We reported a male predominance with a sex ratio of 2.5. The median age was 50 years. The first cause found was diabetes (55%) followed by hypertension (46%). The majority of patients had a dialysis emergency and half could not be dialyzed for financial reasons. Conclusion: Our results highlighted that certain epidemiological parameters of end-stage renal failure are constantly changing, such as frequency, while others remain static, including the main etiologies, gender, and age. However, mortality continues to increase and deserves more attention.展开更多
Evaluation and improvement of quality of care provided to the patients are of crucial importance in the daily clinical practice and in the health policy planning and fnancing. Different tools have been developed, incl...Evaluation and improvement of quality of care provided to the patients are of crucial importance in the daily clinical practice and in the health policy planning and fnancing. Different tools have been developed, includ-ing incident analysis, health technology assessment and clinical audit. The clinical audit consist of mea-suring a clinical outcome or a process, against well-defined standards set on the principles of evidence-based medicine in order to identify the changes needed to improve the quality of care. In particular, patients suffering from chronic renal diseases, present many problems that have been set as topics for clinical audit projects, such as hypertension, anaemia and mineral metabolism management. Although the results of these studies have been encouraging, demonstrating the ef-fectiveness of audit, overall the present evidence is not clearly in favour of clinical audit. These findings call attention to the need to further studies to validate this methodology in different operating scenarios. This review examines the principle of clinical audit, focusing on experiences performed in nephrology settings.展开更多
Understanding the first consultation of people with kidney disease seems to us to be essential to understand the attitude of the referring physician and the nephrologist. The aim was to find out to whom a patient with...Understanding the first consultation of people with kidney disease seems to us to be essential to understand the attitude of the referring physician and the nephrologist. The aim was to find out to whom a patient with kidney disease should be referred in the first instance and for what reason? Hence the evaluation of the prevalence of the first consultation in the nephrology department of the Point G University Hospital in Bamako was made. <strong>Patients and Method:</strong> This was a prospective descriptive study which took place from July 2017 to June 2018 in the nephrology department of the Point G University Hospital. The study included all patients who came to the nephrology department for the first time during this period. <strong>Results:</strong> Between July 2017 and June 2018 at the nephrology and haemodialysis service of the G point University Hospital, we retained 643 out of 1031 patients who came for their first consultation, <i>i.e. </i> 62.36%. There were many patients aged between 41 and 50 years. The average age was 42.6 ± 5.03 years with extremes of 30 and 82 years. The sex ratio (M/F) was in favor of males, 1.14. The majority of patients were referred/evacuated from the referral health centres (57.6%). The majority of patients were referred/evacuated by general practitioners (70.5%). Cardiologists were the main specialists to refer/evacuate patients (21.2%). The main reasons for consultation that led to the first diagnostic hypotheses were: arterial hypertension for vascular nephropathy, glomerular syndrome for glomerular nephropathy, acute uraemia syndrome for acute renal failure, hydronephrosis for obstructive uropathy and finally diabetes for diabetic nephropathy. <strong>Conclusion:</strong> The first consultation in nephrology remains an important step in the management of renal disease, especially when the referral is an emergency. The percentage of referrals is dominated by general practitioners.展开更多
Background: The 2010 US Renal Data System annual report revealed that peritoneal dialysis is used by only 7% of end-stage renal disease patients on chronic dialysis vs. hemodialysis which is used by 93% of such patien...Background: The 2010 US Renal Data System annual report revealed that peritoneal dialysis is used by only 7% of end-stage renal disease patients on chronic dialysis vs. hemodialysis which is used by 93% of such patients, despite documented benefits of peritoneal dialysis over hemodialysis in these cases. Purpose: We examined whether education of nephrology fellows contributed to underutilization of peritoneal dialysis in the US. Methods: Self-report questionnaires were administered electronically to nephrology fellowship training program directors, October 2010-March 2011 (55% response). Results: Median number of training faculty and patients/fellow were significantly lower for peritoneal-dialysis vs. hemodialysis training. Hours of didactic teaching for fellows over their 2-year training period were significantly lower for peritoneal dialysis vs. hemodialysis. Peritoneal dialysis training was 20% of total training vs. 80% for hemodialysis. Most program directors (87%) believed lack of trained faculty in peritoneal dialysis and insufficient peritoneal dialysis patient population contributed to inadequate fellows’ peritoneal dialysis training. Conclusions: Findings suggest that current nephrology fellowship training in peritoneal dialysis is inadequate and contributes to its underutilization.展开更多
Coronavirus disease 2019 has spread across the world and has been classified as a pandemic.It has overwhelmed the healthcare systems.Specifically,it has overstretched the intensive care units and renal replacement the...Coronavirus disease 2019 has spread across the world and has been classified as a pandemic.It has overwhelmed the healthcare systems.Specifically,it has overstretched the intensive care units and renal replacement therapy services in many countries.In this paper,we discuss the reconfiguration of nephrology services in the State of Qatar during the current pandemic.We highlight the key strategies that have been implemented to ensure that renal replacement therapy capacity is not constrained in either the intensive care or ambulatory setting.Some innovative approaches for the safe delivery of ambulatory care to dialysis and kidney transplant patients are also discussed.展开更多
Point of care ultrasonography(POCUS)is emerging as an invaluable tool for guiding patient care at the bedside,providing real-time diagnostic information to clinicians.Today,POCUS is recognized as the fifth pillar of b...Point of care ultrasonography(POCUS)is emerging as an invaluable tool for guiding patient care at the bedside,providing real-time diagnostic information to clinicians.Today,POCUS is recognized as the fifth pillar of bedside clinical examination,alongside inspection,palpation,percussion,and auscultation.In spite of growing interest,the adoption of diagnostic POCUS in nephrology remains limited,and comprehensive training beyond kidney ultrasound is offered in only a few fellowship programs.Moreover,several misconceptions and barriers surround the integration of POCUS into day-to-day nephrology practice.These include myths about its scope,utility,impact on patient outcomes and legal implications.In this minireview,we address some of these issues to encourage wider and proper utilization of POCUS.展开更多
The launch of the World Journal of Nephrology （WJN） has distinct purposes. Its main purpose is to incorporate the fields of diabetes, hypertension, urology, cardiol-ogy and neurology, which are related to kidney di...The launch of the World Journal of Nephrology （WJN） has distinct purposes. Its main purpose is to incorporate the fields of diabetes, hypertension, urology, cardiol-ogy and neurology, which are related to kidney disease, and to make all of our readers, contributors and allied health professionals feel at home with the WJN. The WJN aims to rapidly report new theories, methods and techniques for prevention, diagnosis, treatment, reha-bilitation and nursing skill in the feld of nephrology. The WJN will cover diagnostic imaging, disorders of kidney development, renal obstruction, atrophy and regenera-tion, kidney tumors, renal pharmacology and therapy, renal replacement therapies including transplantation, and Chinese herbal medicine. The WJN issues will in-clude an editorial, frontier, invited review of articles and commentaries in addition to original articles submitted. The WJN will solicit articles from investigators in areas of diabetes and hypertension, and high priority will be given to those articles with an emphasis on the pre-vention of dialysis. Final decision for publication will be based on the merit of the article, language and lucidity.展开更多
Background: The term urinary lithiasis (UL) from the Greek “lithos” refers to the disease characterised by the result of abnormal precipitation of normal constituents of the urine within the urinary tract. The aim o...Background: The term urinary lithiasis (UL) from the Greek “lithos” refers to the disease characterised by the result of abnormal precipitation of normal constituents of the urine within the urinary tract. The aim of this work was to determine the frequency of obstructive renal failure (ORF) of lithiasis origin and to describe the therapeutic indications. Methods: This was a retrospective prospective study in patients hospitalised in the nephrology department of Point G University Hospital for ORF of lithiasis origin over a 26-month period from 1 January 2018 to 1 February 2020 inclusive. Results: Among 1898 hospitalized patients, 32 met the inclusion criteria, i.e. a frequency of 1.7%. The male sex was 68.75% with a sex ratio of 2.2. The mean age was 48.38 ± 13.423 years with extremes of 20 and 65 years. Dysuria and urinary bilharzia were the main uro-nephrological antecedents, accounting for 25% of the cases each. Pain syndrome was the main functional sign, accounting for 100%. Ultrasound of the urinary tract (n = 28) showed stones in 92.85%. These stones were bilateral in 22.22% of cases. The dilatation was pyelocalic in 14 cases (51.8%). The uroscanner showed a pyelic location of the stones in both kidneys;42.1% on the right and 33.3% on the left. Hydronephrosis was the most common dilatation: 37.8% on the right and 29.7% on the left. Renal lithiasis was complicated by acute kidney injury (ARI) in 17 cases (53.1%) versus 15 cases (46.9%) of chronic kidney disease (CKD). Urethral catheter was the means of drainage in 24 (75%) followed by nephrostomy in 8 cases (25%). Nephrolithotomy accounted for 9.4% of cases. The case fatality rate was 28.12% (9 cases). Deaths occurred in the context of uraemic coma 6 cases and cardiorespiratory arrest 3 cases. Conclusions: The management of urinary lithiasis complicated by renal failure calls for the correction of hydrolytic disorders, drainage of the excretory tract and treatment of the stone, of which percutaneous nephrolithotomy seems to be the modality of choice.展开更多
<strong>Introduction:</strong> Percutaneous renal biopsy (PRB) is an essential procedure for the diagnosis and therapeutic management of many primary or secondary nephropathies. <strong>Objectives:&l...<strong>Introduction:</strong> Percutaneous renal biopsy (PRB) is an essential procedure for the diagnosis and therapeutic management of many primary or secondary nephropathies. <strong>Objectives:</strong> To identify the indications, to determine the profile of the diagnosed nephropathies and to evaluate the short-term complications related to the practice of echo-guided PRB at the Martigues hospital center. <strong>Methodology:</strong> This was a retrospective and descriptive study carried out on the records of patients who underwent echo-guided native kidney biopsy from January 1, 2010 to December 31, 2019 in the nephrology department of the Martigues Hospital. <strong>Results:</strong> The analysis of 123 cases of echo-guided PRB involved 76 men and 47 women with a sex ratio of 1.6. The mean age was 55.92 ± 17.80 with age extremes of 16 and 87 years. Glomerular syndromes were the main indication with 42 cases of nephrotic syndrome (34.1%), 15 cases of nephritic syndrome (12.2%), 11 cases of rapidly progressive glomerulonephritis syndrome (8.9%), and 6 cases of recurrent macroscopic hematuria syndrome (4.9%). The histological findings were 47 cases of primary glomerular lesions (38.3%), 32 cases of nephroangiosclerosis lesions (26%), 24 cases of secondary glomerulopathy (19.5%), 9 cases of interstitial nephritis (7.3%), 2 cases of myelomatous nephropathy (1.6%), and 9 cases (7.3%) of unclassified histological lesions. Twenty-two hypertensive patients (40.7%) had nephroangiosclerosis lesions (p = 0.001). The follow-up was simple in 119 patients (96.7%). Macroscopic hematuria was noted in 4 patients (3.3%). It was associated with a perirenal hematoma in 2 patients including 1 transfused case. <strong>Conclusion:</strong> Our data provide an important contribution to the understanding of the prevalence and clinical presentation of renal diseases in the nephrology department of the Martigues hospital center.展开更多
Consider the characteristics of nosocomial infection in hemodialysis patients in the department of nephrology, and summarizing some prevention and control measures. Methods: 162 patients admitted to the department of ...Consider the characteristics of nosocomial infection in hemodialysis patients in the department of nephrology, and summarizing some prevention and control measures. Methods: 162 patients admitted to the department of nephrology of our hospital between January 2020 and January 2021 were selected, and the location, inducing factors and types of infectious bacteria were analyzed according to the clinical baseline data of the patients. Results: among all the patients, the number of nosocomial infections was 26, accounting for 16.05%;The infection sites include: Lung, urinary tract, vascular access, peritonitis, intestinal tract, skin, etc. among them, the proportion of lung and urinary tract is the highest, which is 30.77% and 23.08% respectively;There were about 44 pathogenic bacteria, of which gram-negative bacteria, gram-positive bacteria and fungi accounted for 47.72%, 34.09% and 18.18% respectively;The causes of nosocomial infection in patients with blood glucose are complex, such as: Advanced age (> 60 years old), venous catheter retention, hemoglobin ≤ 90g / L, serum protein 30g / L, and diabetes nephropathy. Conclusion: the risk of nosocomial infection during hemodialysis is very high for patients in nephrology. Therefore, it is necessary to strengthen the overall control of the primary disease and avoid invasive behaviors, so as to gradually reduce the treatment time and minimize the mortality of patients.展开更多
Objective: to explore the effect of implementing high-quality nursing service model on patients with nephropathy. Methods: according to the general situation of accepting kidney disease in the first half of 2020, 100 ...Objective: to explore the effect of implementing high-quality nursing service model on patients with nephropathy. Methods: according to the general situation of accepting kidney disease in the first half of 2020, 100 patients were selected and randomly divided into two groups: observation group and control group. The patients in the control group received common kidney disease care, while the patients in the observation group were treated in a normal way. The curative effects of the two groups of patients in hospital treatment were analyzed and compared. Results: the degree of satisfaction of patients after operation was significantly improved. However, the nurses good nursing concept and quality were significantly improved as compared with the control group. The difference between the above two items was significant (P0.05). Conclusion: the introduction of high-quality medical services is very necessary to improve the overall nursing level of kidney disease and create a good medical environment.展开更多
Introduction: Hypertension (HT) can be the cause or consequence of chronic kidney disease. Its management often requires a multiple therapy due to its severity. Objective: To describe the profile of patients receiving...Introduction: Hypertension (HT) can be the cause or consequence of chronic kidney disease. Its management often requires a multiple therapy due to its severity. Objective: To describe the profile of patients receiving a multiple anti-hypertensive therapy in nephrology practice. Materials and Methods: This was a prospective, descriptive study conducted in the department of Nephrology, Yopougon Teaching Hospital, from January 1 to October 31, 2016. We included all patients admitted to this department who had received at least three anti-hypertensive drugs. Results: Out of a total of 625 hypertensive patients admitted over the study period, we included 120 patients on multiple therapy, i.e. a 19% prevalence. HT was essential in 60% of cases, secondary to chronic glomerulonephritis (CGN) in 25%, to diabetes in 13.3% and to polycystic kidney disease (PKD) in 1.7%. The therapy consisted of the combination of 3 antihy-pertensive drugs in 36.7% of cases, 4 drugs in 49.2% and 5 drugs in 4.2%. The antihypertensive classes used were Calcium channel blockers (CCB) in 99.2% of cases, Diuretics (D) in 87.5%, Angiotensin Converting Enzyme Inhibitors (ACEI) in 70%, Centrally acting medication (C) in 66.7%, Angiotensin Receptor Blockers (ARB) in 25.8% and Beta-blockers (β-) in 6.7%. The main combinations were CCB + D + ACEI + C in 34.2% of cases, CCB + D + ACEI in 23.3%, and CCB + D + ARB + C in 12.5%. The combinations of antihypertensive drugs varied according to the cause of HT with a non-significant difference. Patient outcome was characterized by normal blood pressure in 64.2% of cases and normal renal function in 13.3%. The mortality rate was 17.5%. In multivariate analysis, stage 5 renal disease (p = 0.001), hypertensive retinopathy (p = 0.04) and hemoglobin level < 8 g/dl (p = 0.039) were associated with mortality. Conclusion: Multiple antihypertensive therapy, which is common in nephrology, is related to the severity of HT and not to its cause. We still use centrally acting drugs in combination with the other recommended classes, so as to achieve the target blood pressure.展开更多
Objective: to explore the application effect of high-quality nursing management mode in nursing management of nephrology department. Methods: 80 patients in the department of nephrology of our hospital were randomly d...Objective: to explore the application effect of high-quality nursing management mode in nursing management of nephrology department. Methods: 80 patients in the department of nephrology of our hospital were randomly divided into control group and observation group. The selected time range is from April 2021 to April 2022. The control group adopted conventional nursing mode, while the observation group adopted high-quality nursing management mode on the basis of conventional nursing. The incidence of adverse events, nursing quality score and patients' satisfaction with nursing were compared between the two groups. Results: the incidence of adverse events in the observation group was 5.0%, which was significantly lower than that in the control group (χ2 = 6.3154). In the observation group, the scores of isolation disinfection (95.32 ± 3.31), rescue items (96.33 ± 4.31), nursing document writing (93.62 ± 2.31), graded nursing (93.52 ± 4.31) and safety of nursing quality (94.42 ± 4.31), data patients' satisfaction with nursing in the observation group was 95.0%, significantly higher than that in the control group (χ2 = 6.3161, P < 0.05). Conclusion: the adverse events in the nursing of patients in nephrology department are closely related to the nursing mode. As a new nursing mode, high-quality nursing can reduce the occurrence of adverse events, encourage patients to recognize the clinical nursing work in nephrology department, and play an important role in improving the quality of nursing work in nephrology department.展开更多
Fluoroscopic imaging is widely utilised for diagnostic and therapeutic procedures and is fundamental to the establishment and maintenance of dialysis vascular access.To optimise outcomes and avoid injury to patients a...Fluoroscopic imaging is widely utilised for diagnostic and therapeutic procedures and is fundamental to the establishment and maintenance of dialysis vascular access.To optimise outcomes and avoid injury to patients and healthcare pro-viders,radiation technology must be applied effectively and safely in clinical practice.Radiation safety may be overlooked by nephrology training curricula.This narrative review discusses the theoretical and practical principles of radiation management in fluoroscopy-guided procedures and is intended as a primer for trainees and nephrologists working in interventional settings.展开更多
There is a growing body of clinical research on the utility of synthetic data derivatives,an emerging research tool in medicine.In nephrology,clinicians can use machine learning and artificial intelligence as powerful...There is a growing body of clinical research on the utility of synthetic data derivatives,an emerging research tool in medicine.In nephrology,clinicians can use machine learning and artificial intelligence as powerful aids in their clinical decision-making while also preserving patient privacy.This is especially important given the epidemiology of chronic kidney disease,renal oncology,and hypertension worldwide.However,there remains a need to create a framework for guidance regarding how to better utilize synthetic data as a practical application in this research.展开更多
Machine learning shows enormous potential in facilitating decision-making regarding kidney diseases.With the development of data preservation and processing,as well as the advancement of machine learning algorithms,ma...Machine learning shows enormous potential in facilitating decision-making regarding kidney diseases.With the development of data preservation and processing,as well as the advancement of machine learning algorithms,machine learning is expected to make remarkable breakthroughs in nephrology.Machine learning models have yielded many preliminaries to moderate and several excellent achievements in the fields,including analysis of renal pathological images,diagnosis and prognosis of chronic kidney diseases and acute kidney injury,as well as management of dialysis treatments.However,it is just scratching the surface of the field;at the same time,machine learning andits applications in renal diseases are facing a number of challenges.In this review,we discuss the application status,challenges and future prospects of machine learning in nephrology to help people further understand and improve the capacity for prediction,detection,and care quality in kidney diseases.展开更多
It was not until 1970s that the subspecialty of pediatric nephrology was initiated on the foundation of general pediatrics in China. In 1977, Cooperation Group on Childhood Renal Diseases was organized by Prof. WANG B...It was not until 1970s that the subspecialty of pediatric nephrology was initiated on the foundation of general pediatrics in China. In 1977, Cooperation Group on Childhood Renal Diseases was organized by Prof. WANG Bao-lin （Beijing）, Prof. JIANG Xin-qiu （Nanjing） and Prof. GUO Yi-qing （Shanghai）, which was a milestone for pediatric nephrology in China.展开更多
文摘Ultrasound has long been an essential tool in nephrology,traditionally used for procedures like vascular access and kidney biopsies.Point-of-care ultrasonography(POCUS),a rapidly evolving bedside technology,is now gaining momentum in nephrology by providing real-time imaging to enhance physical examination findings.Unlike comprehensive radiology-performed ultrasound,POCUS focuses on specific clinical questions,providing immediate and actionable insights.This narrative review examines the philosophy behind POCUS,its expanding applications in nephrology,and its impact on patient care,including its role in diagnosing obstructive uropathy,guiding fluid management,and evaluating hemodynamics in cardiorenal syndrome.Additionally,the review addresses barriers to widespread adoption,such as the need for structured training,competency validation,and interdisciplinary cooperation.By integrating POCUS into routine practice,nephrologists can refine diagnostic accuracy,improve patient outcomes,and strengthen the role of bedside medicine.
文摘Point-of-care ultrasound(POCUS)is a limited ultrasound examination performed by the clinician at the bedside,emerging as a complement to physical examination across various medical specialties.In the field of nephrology,its integration has been gradual,primarily limited to guiding procedures like temporary dialysis catheter placement or,in some cases,diagnostic kidney ultrasounds.In reality,the assessment of hemodynamic status at the bedside holds immense value for nephrologists,yet there exists limited awareness among practitioners regarding its implementation.While there is a growing trend towards incorporating multiorgan POCUS training in fellowship programs,private practice nephrologists remain relatively uninformed.This discussion explores the untapped potential of POCUS as a valuable diagnostic tool in everyday nephrology practice,demonstrating its effectiveness in diverse clinical settings,ranging from medical wards to outpatient dialysis units.Additionally,we delve into the challenges hindering its widespread adoption and consider the future trajectory of this innovative approach.
文摘Objective: Chronic end-stage renal failure is a major public health problem in developing countries and is poorly documented. The objective of this study was to describe the epidemiological, diagnostic, therapeutic, and evolutionary aspects of patients admitted for end-stage renal failure to the Department of Nephrology at the University Hospital of Brazzaville. Patients and Methods: This was a descriptive cross-sectional study collecting prospective data that took place over 10 months. We included 128 patients who were exhaustively identified. Sociodemographic, clinical, therapeutic and developmental data were collected using a standardized and pretested pre-established survey form. The EPI info software enabled the analysis and processing of the data. Results: We reported a male predominance with a sex ratio of 2.5. The median age was 50 years. The first cause found was diabetes (55%) followed by hypertension (46%). The majority of patients had a dialysis emergency and half could not be dialyzed for financial reasons. Conclusion: Our results highlighted that certain epidemiological parameters of end-stage renal failure are constantly changing, such as frequency, while others remain static, including the main etiologies, gender, and age. However, mortality continues to increase and deserves more attention.
文摘Evaluation and improvement of quality of care provided to the patients are of crucial importance in the daily clinical practice and in the health policy planning and fnancing. Different tools have been developed, includ-ing incident analysis, health technology assessment and clinical audit. The clinical audit consist of mea-suring a clinical outcome or a process, against well-defined standards set on the principles of evidence-based medicine in order to identify the changes needed to improve the quality of care. In particular, patients suffering from chronic renal diseases, present many problems that have been set as topics for clinical audit projects, such as hypertension, anaemia and mineral metabolism management. Although the results of these studies have been encouraging, demonstrating the ef-fectiveness of audit, overall the present evidence is not clearly in favour of clinical audit. These findings call attention to the need to further studies to validate this methodology in different operating scenarios. This review examines the principle of clinical audit, focusing on experiences performed in nephrology settings.
文摘Understanding the first consultation of people with kidney disease seems to us to be essential to understand the attitude of the referring physician and the nephrologist. The aim was to find out to whom a patient with kidney disease should be referred in the first instance and for what reason? Hence the evaluation of the prevalence of the first consultation in the nephrology department of the Point G University Hospital in Bamako was made. <strong>Patients and Method:</strong> This was a prospective descriptive study which took place from July 2017 to June 2018 in the nephrology department of the Point G University Hospital. The study included all patients who came to the nephrology department for the first time during this period. <strong>Results:</strong> Between July 2017 and June 2018 at the nephrology and haemodialysis service of the G point University Hospital, we retained 643 out of 1031 patients who came for their first consultation, <i>i.e. </i> 62.36%. There were many patients aged between 41 and 50 years. The average age was 42.6 ± 5.03 years with extremes of 30 and 82 years. The sex ratio (M/F) was in favor of males, 1.14. The majority of patients were referred/evacuated from the referral health centres (57.6%). The majority of patients were referred/evacuated by general practitioners (70.5%). Cardiologists were the main specialists to refer/evacuate patients (21.2%). The main reasons for consultation that led to the first diagnostic hypotheses were: arterial hypertension for vascular nephropathy, glomerular syndrome for glomerular nephropathy, acute uraemia syndrome for acute renal failure, hydronephrosis for obstructive uropathy and finally diabetes for diabetic nephropathy. <strong>Conclusion:</strong> The first consultation in nephrology remains an important step in the management of renal disease, especially when the referral is an emergency. The percentage of referrals is dominated by general practitioners.
文摘Background: The 2010 US Renal Data System annual report revealed that peritoneal dialysis is used by only 7% of end-stage renal disease patients on chronic dialysis vs. hemodialysis which is used by 93% of such patients, despite documented benefits of peritoneal dialysis over hemodialysis in these cases. Purpose: We examined whether education of nephrology fellows contributed to underutilization of peritoneal dialysis in the US. Methods: Self-report questionnaires were administered electronically to nephrology fellowship training program directors, October 2010-March 2011 (55% response). Results: Median number of training faculty and patients/fellow were significantly lower for peritoneal-dialysis vs. hemodialysis training. Hours of didactic teaching for fellows over their 2-year training period were significantly lower for peritoneal dialysis vs. hemodialysis. Peritoneal dialysis training was 20% of total training vs. 80% for hemodialysis. Most program directors (87%) believed lack of trained faculty in peritoneal dialysis and insufficient peritoneal dialysis patient population contributed to inadequate fellows’ peritoneal dialysis training. Conclusions: Findings suggest that current nephrology fellowship training in peritoneal dialysis is inadequate and contributes to its underutilization.
基金We thank Dham T,Abdulla A,Joseph J,Joseph S,and all the Hamad Medical Corporation staff for their excellence in patient care in these extremely difficult times.We also thank Hamza Asim for his assistance with computer graphics.
文摘Coronavirus disease 2019 has spread across the world and has been classified as a pandemic.It has overwhelmed the healthcare systems.Specifically,it has overstretched the intensive care units and renal replacement therapy services in many countries.In this paper,we discuss the reconfiguration of nephrology services in the State of Qatar during the current pandemic.We highlight the key strategies that have been implemented to ensure that renal replacement therapy capacity is not constrained in either the intensive care or ambulatory setting.Some innovative approaches for the safe delivery of ambulatory care to dialysis and kidney transplant patients are also discussed.
文摘Point of care ultrasonography(POCUS)is emerging as an invaluable tool for guiding patient care at the bedside,providing real-time diagnostic information to clinicians.Today,POCUS is recognized as the fifth pillar of bedside clinical examination,alongside inspection,palpation,percussion,and auscultation.In spite of growing interest,the adoption of diagnostic POCUS in nephrology remains limited,and comprehensive training beyond kidney ultrasound is offered in only a few fellowship programs.Moreover,several misconceptions and barriers surround the integration of POCUS into day-to-day nephrology practice.These include myths about its scope,utility,impact on patient outcomes and legal implications.In this minireview,we address some of these issues to encourage wider and proper utilization of POCUS.
文摘The launch of the World Journal of Nephrology （WJN） has distinct purposes. Its main purpose is to incorporate the fields of diabetes, hypertension, urology, cardiol-ogy and neurology, which are related to kidney disease, and to make all of our readers, contributors and allied health professionals feel at home with the WJN. The WJN aims to rapidly report new theories, methods and techniques for prevention, diagnosis, treatment, reha-bilitation and nursing skill in the feld of nephrology. The WJN will cover diagnostic imaging, disorders of kidney development, renal obstruction, atrophy and regenera-tion, kidney tumors, renal pharmacology and therapy, renal replacement therapies including transplantation, and Chinese herbal medicine. The WJN issues will in-clude an editorial, frontier, invited review of articles and commentaries in addition to original articles submitted. The WJN will solicit articles from investigators in areas of diabetes and hypertension, and high priority will be given to those articles with an emphasis on the pre-vention of dialysis. Final decision for publication will be based on the merit of the article, language and lucidity.
文摘Background: The term urinary lithiasis (UL) from the Greek “lithos” refers to the disease characterised by the result of abnormal precipitation of normal constituents of the urine within the urinary tract. The aim of this work was to determine the frequency of obstructive renal failure (ORF) of lithiasis origin and to describe the therapeutic indications. Methods: This was a retrospective prospective study in patients hospitalised in the nephrology department of Point G University Hospital for ORF of lithiasis origin over a 26-month period from 1 January 2018 to 1 February 2020 inclusive. Results: Among 1898 hospitalized patients, 32 met the inclusion criteria, i.e. a frequency of 1.7%. The male sex was 68.75% with a sex ratio of 2.2. The mean age was 48.38 ± 13.423 years with extremes of 20 and 65 years. Dysuria and urinary bilharzia were the main uro-nephrological antecedents, accounting for 25% of the cases each. Pain syndrome was the main functional sign, accounting for 100%. Ultrasound of the urinary tract (n = 28) showed stones in 92.85%. These stones were bilateral in 22.22% of cases. The dilatation was pyelocalic in 14 cases (51.8%). The uroscanner showed a pyelic location of the stones in both kidneys;42.1% on the right and 33.3% on the left. Hydronephrosis was the most common dilatation: 37.8% on the right and 29.7% on the left. Renal lithiasis was complicated by acute kidney injury (ARI) in 17 cases (53.1%) versus 15 cases (46.9%) of chronic kidney disease (CKD). Urethral catheter was the means of drainage in 24 (75%) followed by nephrostomy in 8 cases (25%). Nephrolithotomy accounted for 9.4% of cases. The case fatality rate was 28.12% (9 cases). Deaths occurred in the context of uraemic coma 6 cases and cardiorespiratory arrest 3 cases. Conclusions: The management of urinary lithiasis complicated by renal failure calls for the correction of hydrolytic disorders, drainage of the excretory tract and treatment of the stone, of which percutaneous nephrolithotomy seems to be the modality of choice.
文摘<strong>Introduction:</strong> Percutaneous renal biopsy (PRB) is an essential procedure for the diagnosis and therapeutic management of many primary or secondary nephropathies. <strong>Objectives:</strong> To identify the indications, to determine the profile of the diagnosed nephropathies and to evaluate the short-term complications related to the practice of echo-guided PRB at the Martigues hospital center. <strong>Methodology:</strong> This was a retrospective and descriptive study carried out on the records of patients who underwent echo-guided native kidney biopsy from January 1, 2010 to December 31, 2019 in the nephrology department of the Martigues Hospital. <strong>Results:</strong> The analysis of 123 cases of echo-guided PRB involved 76 men and 47 women with a sex ratio of 1.6. The mean age was 55.92 ± 17.80 with age extremes of 16 and 87 years. Glomerular syndromes were the main indication with 42 cases of nephrotic syndrome (34.1%), 15 cases of nephritic syndrome (12.2%), 11 cases of rapidly progressive glomerulonephritis syndrome (8.9%), and 6 cases of recurrent macroscopic hematuria syndrome (4.9%). The histological findings were 47 cases of primary glomerular lesions (38.3%), 32 cases of nephroangiosclerosis lesions (26%), 24 cases of secondary glomerulopathy (19.5%), 9 cases of interstitial nephritis (7.3%), 2 cases of myelomatous nephropathy (1.6%), and 9 cases (7.3%) of unclassified histological lesions. Twenty-two hypertensive patients (40.7%) had nephroangiosclerosis lesions (p = 0.001). The follow-up was simple in 119 patients (96.7%). Macroscopic hematuria was noted in 4 patients (3.3%). It was associated with a perirenal hematoma in 2 patients including 1 transfused case. <strong>Conclusion:</strong> Our data provide an important contribution to the understanding of the prevalence and clinical presentation of renal diseases in the nephrology department of the Martigues hospital center.
文摘Consider the characteristics of nosocomial infection in hemodialysis patients in the department of nephrology, and summarizing some prevention and control measures. Methods: 162 patients admitted to the department of nephrology of our hospital between January 2020 and January 2021 were selected, and the location, inducing factors and types of infectious bacteria were analyzed according to the clinical baseline data of the patients. Results: among all the patients, the number of nosocomial infections was 26, accounting for 16.05%;The infection sites include: Lung, urinary tract, vascular access, peritonitis, intestinal tract, skin, etc. among them, the proportion of lung and urinary tract is the highest, which is 30.77% and 23.08% respectively;There were about 44 pathogenic bacteria, of which gram-negative bacteria, gram-positive bacteria and fungi accounted for 47.72%, 34.09% and 18.18% respectively;The causes of nosocomial infection in patients with blood glucose are complex, such as: Advanced age (> 60 years old), venous catheter retention, hemoglobin ≤ 90g / L, serum protein 30g / L, and diabetes nephropathy. Conclusion: the risk of nosocomial infection during hemodialysis is very high for patients in nephrology. Therefore, it is necessary to strengthen the overall control of the primary disease and avoid invasive behaviors, so as to gradually reduce the treatment time and minimize the mortality of patients.
文摘Objective: to explore the effect of implementing high-quality nursing service model on patients with nephropathy. Methods: according to the general situation of accepting kidney disease in the first half of 2020, 100 patients were selected and randomly divided into two groups: observation group and control group. The patients in the control group received common kidney disease care, while the patients in the observation group were treated in a normal way. The curative effects of the two groups of patients in hospital treatment were analyzed and compared. Results: the degree of satisfaction of patients after operation was significantly improved. However, the nurses good nursing concept and quality were significantly improved as compared with the control group. The difference between the above two items was significant (P0.05). Conclusion: the introduction of high-quality medical services is very necessary to improve the overall nursing level of kidney disease and create a good medical environment.
文摘Introduction: Hypertension (HT) can be the cause or consequence of chronic kidney disease. Its management often requires a multiple therapy due to its severity. Objective: To describe the profile of patients receiving a multiple anti-hypertensive therapy in nephrology practice. Materials and Methods: This was a prospective, descriptive study conducted in the department of Nephrology, Yopougon Teaching Hospital, from January 1 to October 31, 2016. We included all patients admitted to this department who had received at least three anti-hypertensive drugs. Results: Out of a total of 625 hypertensive patients admitted over the study period, we included 120 patients on multiple therapy, i.e. a 19% prevalence. HT was essential in 60% of cases, secondary to chronic glomerulonephritis (CGN) in 25%, to diabetes in 13.3% and to polycystic kidney disease (PKD) in 1.7%. The therapy consisted of the combination of 3 antihy-pertensive drugs in 36.7% of cases, 4 drugs in 49.2% and 5 drugs in 4.2%. The antihypertensive classes used were Calcium channel blockers (CCB) in 99.2% of cases, Diuretics (D) in 87.5%, Angiotensin Converting Enzyme Inhibitors (ACEI) in 70%, Centrally acting medication (C) in 66.7%, Angiotensin Receptor Blockers (ARB) in 25.8% and Beta-blockers (β-) in 6.7%. The main combinations were CCB + D + ACEI + C in 34.2% of cases, CCB + D + ACEI in 23.3%, and CCB + D + ARB + C in 12.5%. The combinations of antihypertensive drugs varied according to the cause of HT with a non-significant difference. Patient outcome was characterized by normal blood pressure in 64.2% of cases and normal renal function in 13.3%. The mortality rate was 17.5%. In multivariate analysis, stage 5 renal disease (p = 0.001), hypertensive retinopathy (p = 0.04) and hemoglobin level < 8 g/dl (p = 0.039) were associated with mortality. Conclusion: Multiple antihypertensive therapy, which is common in nephrology, is related to the severity of HT and not to its cause. We still use centrally acting drugs in combination with the other recommended classes, so as to achieve the target blood pressure.
文摘Objective: to explore the application effect of high-quality nursing management mode in nursing management of nephrology department. Methods: 80 patients in the department of nephrology of our hospital were randomly divided into control group and observation group. The selected time range is from April 2021 to April 2022. The control group adopted conventional nursing mode, while the observation group adopted high-quality nursing management mode on the basis of conventional nursing. The incidence of adverse events, nursing quality score and patients' satisfaction with nursing were compared between the two groups. Results: the incidence of adverse events in the observation group was 5.0%, which was significantly lower than that in the control group (χ2 = 6.3154). In the observation group, the scores of isolation disinfection (95.32 ± 3.31), rescue items (96.33 ± 4.31), nursing document writing (93.62 ± 2.31), graded nursing (93.52 ± 4.31) and safety of nursing quality (94.42 ± 4.31), data patients' satisfaction with nursing in the observation group was 95.0%, significantly higher than that in the control group (χ2 = 6.3161, P < 0.05). Conclusion: the adverse events in the nursing of patients in nephrology department are closely related to the nursing mode. As a new nursing mode, high-quality nursing can reduce the occurrence of adverse events, encourage patients to recognize the clinical nursing work in nephrology department, and play an important role in improving the quality of nursing work in nephrology department.
文摘Fluoroscopic imaging is widely utilised for diagnostic and therapeutic procedures and is fundamental to the establishment and maintenance of dialysis vascular access.To optimise outcomes and avoid injury to patients and healthcare pro-viders,radiation technology must be applied effectively and safely in clinical practice.Radiation safety may be overlooked by nephrology training curricula.This narrative review discusses the theoretical and practical principles of radiation management in fluoroscopy-guided procedures and is intended as a primer for trainees and nephrologists working in interventional settings.
文摘There is a growing body of clinical research on the utility of synthetic data derivatives,an emerging research tool in medicine.In nephrology,clinicians can use machine learning and artificial intelligence as powerful aids in their clinical decision-making while also preserving patient privacy.This is especially important given the epidemiology of chronic kidney disease,renal oncology,and hypertension worldwide.However,there remains a need to create a framework for guidance regarding how to better utilize synthetic data as a practical application in this research.
基金This work was supported by grants from the National Natural Science Foundation of China(Nos.61971441,61671479,and 81804056)the National Key R&D Program of China(No.2016YFC1305500).
文摘Machine learning shows enormous potential in facilitating decision-making regarding kidney diseases.With the development of data preservation and processing,as well as the advancement of machine learning algorithms,machine learning is expected to make remarkable breakthroughs in nephrology.Machine learning models have yielded many preliminaries to moderate and several excellent achievements in the fields,including analysis of renal pathological images,diagnosis and prognosis of chronic kidney diseases and acute kidney injury,as well as management of dialysis treatments.However,it is just scratching the surface of the field;at the same time,machine learning andits applications in renal diseases are facing a number of challenges.In this review,we discuss the application status,challenges and future prospects of machine learning in nephrology to help people further understand and improve the capacity for prediction,detection,and care quality in kidney diseases.
文摘It was not until 1970s that the subspecialty of pediatric nephrology was initiated on the foundation of general pediatrics in China. In 1977, Cooperation Group on Childhood Renal Diseases was organized by Prof. WANG Bao-lin （Beijing）, Prof. JIANG Xin-qiu （Nanjing） and Prof. GUO Yi-qing （Shanghai）, which was a milestone for pediatric nephrology in China.
