Pushed by the results of a preceding publication on the possibly Quaternary Jebel Waqf as Suwwan Meteorite Crater, Jordan [5], where an amazing coincidence of Rapid Climate Changes (RCCs) with Rise and Fall of Neolith...Pushed by the results of a preceding publication on the possibly Quaternary Jebel Waqf as Suwwan Meteorite Crater, Jordan [5], where an amazing coincidence of Rapid Climate Changes (RCCs) with Rise and Fall of Neolithic and Bronze Age Cultures became evident for the Near/Middle East, this paper deals with the same subject, however, relating to the complete Holocene period in the same area and, additionally, in Central Europe as well. By application of modern climatic data [6] comprising isotope analysis (δ18O, 14C, 10Be), acid and aerosol events, and greenhouse gases (CO2, CH4) Greenland ice cores as well as other astro-/geophysical and geological parameters, an overwhelming coincidence/relation/interdependence of both natural and cultural evidences becomes obvious throughout the last 15,000 years across the Northern Hemisphere. Apart from solar output and other astrophysical processes, most important climate- and Earth-related parameters are Mega-Volcanism (i.e.Santorini Greece: ~3640 yr cal. B. P.), Impact Events (i.e. during Mesolithic: ~9600 yr cal. B. P), rapid oceanic current change (DO-Events), and Plate Tectonics (possibly Atlantis-Event: ~11,500 yr cal. B.P. = Pleistocene/Holocene boundary). The most essential parameter is a significant temperature change related to more or less restricted latitude realms of the Northern Hemisphere. Thus, glacier advance/retreat controls the mobility of peoples (i.e. Nations' Migration, Teutonic Empires) and the access to ore deposits (Au, Ag, Cu, Sn, Zn, Pb, Fe) located in Alpine Mountain Ranges (i.e. End-Neolithic, Early Bronze Age). Myths like the Gilgamesh Epos and John Apocalypse convincingly reveal realistic contents relating to natural hazards like tsunamis, impact and flooding events. They unmisunderstandably make obvious that Myths may provide valuable contributions, especially to Geosciences. Some of the controlling parameters interrelate with others or present a kind of hierarchy: Mega-Volcanism/impact events à ejecta à wildfires, heat storms à cosmic winter, sint winter à stop of photosynthesis à mass extinction environmental pollution à greenhouse effects. Significant events (21 cases in total) occurred on i.e.展开更多
Tinnitus is a concerning condition that affects most adults worldwide,with a prevalence of 6.7%.Theories of tinnitus have explained that an increase in spontaneous neural activity at the level of the thalamus could in...Tinnitus is a concerning condition that affects most adults worldwide,with a prevalence of 6.7%.Theories of tinnitus have explained that an increase in spontaneous neural activity at the level of the thalamus could induce tinnitus.There are no standardized objective tests for tinnitus assessment because of its multifaceted nature.Hence,the current study aimed to explore the effect of Tinnitus on Latency and Amplitude of the Auditory Middle Latency Response in Audiological Attendees.The study recruited 50 individuals(25 normals and 25 individuals with tinnitus)who underwent audiological evaluations like Pure tone audiometry,immittance,pitch and loudness matching,THI and middle latency response.The IHS program was used to record MLR,which was obtained using tone burst stimuli of 500 Hz,1 KHz,2 KHz,and 4 KHz at a rate of 7.1/s with a constant duration of 5 ms,for a total of 1500 sweeps.As a covariate,pure tone thresholds were one of the variabilities that were addressed by ANCOVA.The amplitude of the Pa component varied significantly between the tinnitus and control groups,according to the MLR data and no other components of MLR reached that significance.Furthermore,there was no discernible variation in the latency or amplitude of MLR among any of the other components.The latency of the waveforms increased as the stimulus frequency increased.Karl Pearson correlation coefficient showed no significant correlation between THI scores and any of the outcome measures except for Pa amplitude.As the Pa component of MLR showed maximum changes between controls and individuals with tinnitus,the Pa component could be considered a potential tool for identifying neurophysiological changes related to tinnitus.展开更多
BACKGROUND Middle meningeal artery embolization(MMAE)is emerging as a promising treatment for chronic subdural hematoma(CSDH),serving both as an adjunct to surgery and as a primary therapeutic option depending on pati...BACKGROUND Middle meningeal artery embolization(MMAE)is emerging as a promising treatment for chronic subdural hematoma(CSDH),serving both as an adjunct to surgery and as a primary therapeutic option depending on patient presentation.Due to its low recurrence rate and minimal complications,MMAE has gained increasing acceptance among clinicians in recent years.This report presents a case of diplopia following MMAE due to the presence of a potential anastomotic artery,aiming to enhance awareness of this complication.CASE SUMMARY A 60-year-old male patient presented with a headache following head trauma,and cranial computed tomography revealed a left-sided CSDH.The patient underwent left MMAE;however,polyvinyl alcohol particles inadvertently flowed into the lacrimal artery through an anastomotic artery,resulting in diplopia due to impaired abduction of the left eye.The diplopia resolved by postoperative day 40.The patient’s headache resolved by postoperative day 7,and the hematoma completely resolved by postoperative day 108.CONCLUSION Potential anastomotic arteries in the middle meningeal artery(MMA)can lead to serious complications.Superselective angiography of the MMA or its branches prior to embolization is essential.Performing embolization distal to potential anastomotic sites can reduce risks,and the presence of an anastomosis may warrant coil embolization or termination of the procedure.展开更多
Wetlands play a critical role in the global environment.The Middle Yangtze River Basin(MYRB),known for its abundant wetland resources,has experienced notable changes resulting from the complex interplay of environment...Wetlands play a critical role in the global environment.The Middle Yangtze River Basin(MYRB),known for its abundant wetland resources,has experienced notable changes resulting from the complex interplay of environmental factors.Therefore,we investigated the spatiotemporal characteristics of wetland ecological quality in the MYRB from 2001 to 2020.Utilizing the random forest(RF)regression algorithm and patch-generated land-use simulation(PLUS)model,we forecasted variations in wetland habitat quality and their determinants under the Shared Socioeconomic Pathway-Representative Concentration Pathway(SSPRCP)framework from 2035 to 2095.The main findings are as follows:(1)The RF algorithm was optimal for land-use and land-cover(LULC)classification in the MYRB from 2001 to 2020,when notable changes were observed in water bodies and buildings.However,the forested area exhibited an increase and decrease of 3.9%and 1.2%under the SSP1-2.6 and SSP5-8.5 scenarios,respectively,whereas farmland exhibited a diminishing trend.(2)Wetlands were primarily concentrated in the central and eastern MYRB,with counties in the southwest exhibiting superior ecological-environmental quality from 2001 to 2020.Notably,wetland coverage revealed significantly high level,significant changes,frequent but relatively minor changes under the SSP1-2.6,SSP2-4.5,and SSP 5-8.5 scenarios,respectively.(3)Regions with lower habitat quality were primarily concentrated in urbanized areas characterized by frequent human activities,indicating a clear degradation in habitat quality across different scenarios.In conclusion,we established a foundational framework for future investigations into the eco-hydrological processes and ecosystem quality of watersheds.展开更多
This paper discusses the characteristics and formation mechanism of thin dolomite reservoirs in the lower submember of the second member of the Permian Maokou Formation(lower Mao 2 Member)in the Wusheng-Tongnan area o...This paper discusses the characteristics and formation mechanism of thin dolomite reservoirs in the lower submember of the second member of the Permian Maokou Formation(lower Mao 2 Member)in the Wusheng-Tongnan area of the Sichuan Basin,SW China,through comprehensive analysis of geological,geophysical and geochemical data.The reservoir rocks of the lower Mao 2 Member are dominated by porphyritic vuggy dolomite and calcareous dolomite or dolomitic limestone,which have typical karst characteristics of early diagenetic stage.The dolomites at the edge of the karst system and in the fillings have dissolved estuaries,and the dolomite breccia has micrite envelope and rim cement at the edge,indicating that dolomitization is earlier than the early diagenetic karstification.The shoal facies laminated dolomite is primarily formed by the seepage reflux dolomitization of moderate-salinity seawater.The key factors of reservoir formation are the bioclastic shoal deposition superimposed with seepgae reflux dolomitization and the karstification of early diagenetic stage,which are locally reformed by fractures and hydrothermal processes.The development of dolomite vuggy reservoir is closely related to the upward-shallowing sequence,and mainly occurs in the late highstand of the fourth-order cycle.Moreover,the size of dolomite is closely related to formation thickness,and it is concentrated in the formation thickness conversion area,followed by the thinner area.According to the understanding of insufficient accommodation space in the geomorphic highland and the migration of granular shoal to geomorphic lowland in the late highstand of the third-order cycle,it is proposed that the large-scale shoal-controlled dolomite reservoirs are distributed along structural highs and slopes,and the reservoir-forming model with shoal,dolomitization and karstification jointly controlled by the microgeomorphy and sea-level fluctuation in the sedimentary period is established.On this basis,the paleogeomorphology in the lower Mao 2 Member is restored using well-seismic data,and the reservoir distribution is predicted.The prediction results have been verified by the latest results of exploration wells and tests,which provide an important reference for the prediction of thin dolomite reservoirs under similar geological setting.展开更多
The chronic occlusion of intracranial arteries generally has no or mild clinical symptoms,and the clinical symptoms of acute cerebral artery occlusion are mostly manifested as severe cerebral infarction symptoms,which...The chronic occlusion of intracranial arteries generally has no or mild clinical symptoms,and the clinical symptoms of acute cerebral artery occlusion are mostly manifested as severe cerebral infarction symptoms,which often make early diagnosis difficult,thus losing the best treatment opportunity.Once cerebral infarction occurs,the consequences are difficult to recover.This is also an important reason for the high misdiagnosis rate and mortality of this disease.In this paper,the characteristics of the disease were analyzed to provide clinical reference.展开更多
Human temporal bone specimens are used in experiments to measure the sound transfer function of the middle ear.This standard method for the development of middle ear implants requires temporal bones that possess appro...Human temporal bone specimens are used in experiments to measure the sound transfer function of the middle ear.This standard method for the development of middle ear implants requires temporal bones that possess appropriate mechanical properties and structural stability and are free from pathological conditions.A laser Doppler vibrometer is commonly employed to measure the vibration of the stapes footplate.These experiments are typically conducted in the middle ear by leaving the inner ear intact,exposing the stapes footplate through the tympanic cavity,and directing the laser beam onto the footplate.However,previous studies have shown that the influence of inner ear impedance on the middle ear transfer function cannot be ignored,and any surgical manipulation may cause a change in inner ear pressure,resulting in instability in the middle ear transfer function.Therefore,this study aims to eliminate the influence of the inner ear and to establish a new experimental method in human temporal bone specimens that is more suitable for the study of sound conduction in middle ear implants.As a result,a range for middle ear transfer function was developed,which serves as a reference for assessing the conformity of temporal bone specimens to experimental standards,and the stability of this range was demonstrated under experimental conditions.展开更多
BACKGROUND Picky eating is a commonly observed behavior among children globally,negatively impacting their physical and mental growth.Although common characteristics distinguish peaky eaters,including food selectivity...BACKGROUND Picky eating is a commonly observed behavior among children globally,negatively impacting their physical and mental growth.Although common characteristics distinguish peaky eaters,including food selectivity,food neophobia,and food avoidance,there is no clear definition to assess this behavior.Due to the unavailability of data regarding picky eating,it wasn’t easy to estimate its prevalence.AIM To develop a regional protocol to help healthcare professionals identify and manage mild and moderate picky eating cases.METHODS A virtual roundtable discussion was held in April 2021 to gather the opinions of seven pediatricians and two pediatric dietitians from eight Middle Eastern countries who had great experience in the management of picky eating.The discussion covered different topics,including clearly defining mild and moderate picky eating,identifying the role of diet fortification in these cases,and the possibility of developing a systematic approach to diet fortification.RESULTS The panel identified picky eating as consuming an inadequate amount and variety of foods by rejecting familiar and unfamiliar food.Most of the time,moderate picky eating cases had micronutrient deficiencies with over-or undernutrition;the mild cases only showed inadequate food consumption and/or poor diet quality.Paying attention to the organic red flags like growth faltering and development delay and behavioral red flags,including food fixation and anticipatory gagging,will help healthcare professionals evaluate the picky eaters and the caregivers to care for their children.Although dietary supplementation and commercial food fortification play an important role in picky eating,they were no benefit in the Middle East.CONCLUSION The panel agreed that food fortification through a food-first approach and oral nutritional supplements would be the best for Middle Eastern children.These recommendations would facilitate identifying and managing picky-eating children in the Middle East.展开更多
Objective:To present a rare case of glial heterotopia in the middle ear occurring in association with cholesteatoma.Patient and Intervention:A 56-year-old female presented with right-sided hearing loss and otorrhea.EN...Objective:To present a rare case of glial heterotopia in the middle ear occurring in association with cholesteatoma.Patient and Intervention:A 56-year-old female presented with right-sided hearing loss and otorrhea.ENT examination and CT imaging revealed middle ear cholesteatoma.Right canal wall down mastoidectomy with type Ⅲ tympanoplasty revealed a well-demarcated,soft,pinkish mass in the right middle ear without tegmen tympani dehiscence.Histopathological analysis confirmed glial heterotopia.Main Outcome Measures:Complete cholesteatoma resection,resolution of otorrhea,absence of neurological complications,and right-sided hearing improvement.Results:The patient demonstrated an uneventful postoperative recovery.At the five-month follow-up,tympanoplasty outcomes remained stable.Repeat imaging confirmed absence of skull base defects,with clinical resolution of otorrhea.No postoperative neurological complications(including cerebrospinal fluid leakage)were observed.Conclusions:Middle ear glial heterotopia is a rare entity that may be discovered incidentally or in association with infection/cholesteatoma.Definitive management requires surgical excision of the heterotopic tissue and concurrent repair of skull base bone defects when identified.Preoperative imaging evaluation with CT or MRI can be valuable to delineate anatomical relationships and exclude intracranial connections.展开更多
The Middle East has long been in turmoil,and the new round of the Palestinian-Israeli conflict has further highlighted the urgency of security governance in the region.The Global Security Initiative(GSI)proposed by Ch...The Middle East has long been in turmoil,and the new round of the Palestinian-Israeli conflict has further highlighted the urgency of security governance in the region.The Global Security Initiative(GSI)proposed by China provides theoretical guidance and practical paths for China’s participation in Middle East security governance.China’s engagement in Middle East security governance not only meets the expectations of Middle East countries but also fully demonstrates its responsibility as a major country,which is of great significance for China to explore participation in global security governance and address the global security deficit.展开更多
Chronic subdural hematoma is essentially managed by surgical intervention.In recent times,middle meningeal artery embolisation has emerged as a less invasive procedure in such cases.The use of fine catheters to select...Chronic subdural hematoma is essentially managed by surgical intervention.In recent times,middle meningeal artery embolisation has emerged as a less invasive procedure in such cases.The use of fine catheters to selectively embolise the specific involved branches of the middle meningeal artery using polyvinyl alcohol particles looks promising;however,the presence of anastomotic arteries can result in reflux and embolisation of these atypical branches,causing a myriad of complications.There is a need to identify these abnormal vessels in time to have a positive outcome with the least complications.展开更多
Erratumto:Journal of Earth Science https://doi.org/10.1007/s12583-023-1946-6 The original version of this article unfortunately contained three mistakes.1.The presentation of Equation(4)was incorrect.The corrected one...Erratumto:Journal of Earth Science https://doi.org/10.1007/s12583-023-1946-6 The original version of this article unfortunately contained three mistakes.1.The presentation of Equation(4)was incorrect.The corrected one is given below.展开更多
With the development of social economy,the subjects,methods,and contents of ideological and political education have undergone changes.It is not only necessary to give full play to the role of ideological and politica...With the development of social economy,the subjects,methods,and contents of ideological and political education have undergone changes.It is not only necessary to give full play to the role of ideological and political courses but also to focus on exploring teaching forms and methods to promote the realization of the goal of“fostering virtue through education”.Under the background of the new curriculum reform,in middle school biology teaching,it is necessary to implement“fostering virtue through education”,carry out ideological and political education,effectively improve the effect of talent training,and promote the development of students’values.From the perspective of middle school biology,this paper discusses the necessity of integrating curriculum ideology and politics,analyzes the principles that should be followed in the infiltration of ideological and political elements,and puts forward specific strategies for biology teaching practice,aiming to cultivate students’good values and lay a solid foundation for their subsequent knowledge learning.展开更多
Background The middle ear pneumatic system(MEPS)supports pressure balance,essential for sound conduction.Its volume and surface area are key indicators of pneumatization and ventilation,yet their specific contribution...Background The middle ear pneumatic system(MEPS)supports pressure balance,essential for sound conduction.Its volume and surface area are key indicators of pneumatization and ventilation,yet their specific contributions to pressure regulation need further exploration.Objective To evaluate the accuracy and sensitivity of parameters characterizing the MEPS,including volume(V),surface area(S),and surface-area-to-volume ratio(S/V),in normal ears.Materials and Methods We collected CT images of the temporal bone from 63 normal ears for this study.The volume(V),surface area(S),and surface-area-to-volume ratio(S/V)of the MEPS were measured and calculated using three-dimensional reconstruction technology.Statistical methods were used to process the data and determine the 95%reference range for the S,V,and S/V of the MEPS in the normal ear.At the same time,we analyzed the impact of differences in gender and the left and right sides on the measurements.Results The 95%reference values for the S,V,and S/V of the MEPS in normal ears were 1057.10~18239.16 mm²,609.16~9854.11 mm^(3),and 1.39~2.52 mm^(-1) respectively.There were no significant differences in the measurements between genders and between the left and right sides.Conclusions and Significance This study has established the 95%reference values for the S,V,and S/V of the MEPS in normal ears,which were 1057.10-18239.16 mm²,609.16-9854.11 mm^(3),and 1.39-2.52 mm^(-1) respectively.We found that while there is a wide variation in the V values among normal ears,there is less variability in the S/V values.This structural characteristic suggests that changes in the S/V value may have a more significant impact on the balance of middle ear pressure,and it provides important reference data for the construction and functional reconstruction of three-dimensional models of the MEPS.These findings may aid in diagnosing middle ear disorders,such as otitis media with effusion,and guide interventions to restore pressure balance.展开更多
Cenozoic trachytes are characteristic of some active volcanic fields in China.In particular,the origin and mechanisms of the evolution of trachytes from the Tianchi(Changbaishan)volcano(TV,China/North Korea)are poorly...Cenozoic trachytes are characteristic of some active volcanic fields in China.In particular,the origin and mechanisms of the evolution of trachytes from the Tianchi(Changbaishan)volcano(TV,China/North Korea)are poorly known.Here,we present new geochronological,geochemical and isotopic data on two trachytic suites outcropping on the northern and southern upper slopes of TV.Detailed zircon laser ablation-multicollector-inductively coupled plasma-mass spectrometry(LA-MC-ICP-MS)U-Pb dating,Rb-Sr isochron dating of plagioclase and hornblende,^(40)Ar/^(39)Ar chronology with mineral chemistry,whole-rock element and Sr-Nd-Pb isotope data are used to explore their origins and evolutionary mechanisms during the late Middle Pleistocene.Our data indicate that the trachytes mainly consist of sanidine,orthoclase and plagioclase,with minor albite,quartz and hornblende.They formed at 0.353-0.346 Ma(lava flow from the northern slope)and 0.383-0.311 Ma(lava flow from the southern slope),respectively.The TV trachytes are characterized by high K_(2)O/Na_(2)O and AR values,with low A/CNK and Mg~#values.They are enriched in rare earth elements(REEs;except Eu),depleted in Sr and Ba,crystallizing at 742-858℃.The TV trachytes have high(^(87)Sr/^(86)Sr)_i values(0.70776-0.71195),positiveε_(Nd)(t)values(0.61-2.93)and radiogenic^(206)Pb/^(204)Pb values(17.515-17.806).These values are similar to those of the Pleistocene and Holocene TV trachytes.Geochemical data indicate that they were formed by fractional crystallization from a basaltic melt and assimilated upper crust material.The trace element pattern of the studied trachytes is consistent with an evolution from basaltic melts representative of an enriched mantle source.The vent from which the trachytic magma was erupted probably collapsed inside the caldera during the TV'Millennium'eruption(ME)in 946 AD.The contemporaneous emission of basaltic and trachytic magma during the Middle-Late Pleistocene suggests the coexistence of fissural basaltic volcanism and central-type trachytic volcanism,the latter of which was associated with a magma chamber in the upper crust during the TV cone-construction stage.展开更多
The Silk Road witnessed the exchange,integration,and innovation of medicine between ancient China and the ancient Middle East.This article outlines a panoramic historical picture of medical interchanges between ancien...The Silk Road witnessed the exchange,integration,and innovation of medicine between ancient China and the ancient Middle East.This article outlines a panoramic historical picture of medical interchanges between ancient China and the ancient Middle East along the Silk Road by multilingual literature research,textual criticism and scientific methods.Through the exchange of medicinal materials,the supplement of prescriptions,the reference of dosage forms,and the absorption of medical concepts,the two major medical systems along the Silk Road have interacted and integrated.Anchored in the political cooperation,sustained by translation network,and promoted by commercial intercourse,this medical dialogue shows the openness and adaptability of traditional medicine.This interchange history provides a historical paradigm for the modernization of traditional medicine,cross-cultural collaboration,and the building of the Silk Road of Health.展开更多
文摘Pushed by the results of a preceding publication on the possibly Quaternary Jebel Waqf as Suwwan Meteorite Crater, Jordan [5], where an amazing coincidence of Rapid Climate Changes (RCCs) with Rise and Fall of Neolithic and Bronze Age Cultures became evident for the Near/Middle East, this paper deals with the same subject, however, relating to the complete Holocene period in the same area and, additionally, in Central Europe as well. By application of modern climatic data [6] comprising isotope analysis (δ18O, 14C, 10Be), acid and aerosol events, and greenhouse gases (CO2, CH4) Greenland ice cores as well as other astro-/geophysical and geological parameters, an overwhelming coincidence/relation/interdependence of both natural and cultural evidences becomes obvious throughout the last 15,000 years across the Northern Hemisphere. Apart from solar output and other astrophysical processes, most important climate- and Earth-related parameters are Mega-Volcanism (i.e.Santorini Greece: ~3640 yr cal. B. P.), Impact Events (i.e. during Mesolithic: ~9600 yr cal. B. P), rapid oceanic current change (DO-Events), and Plate Tectonics (possibly Atlantis-Event: ~11,500 yr cal. B.P. = Pleistocene/Holocene boundary). The most essential parameter is a significant temperature change related to more or less restricted latitude realms of the Northern Hemisphere. Thus, glacier advance/retreat controls the mobility of peoples (i.e. Nations' Migration, Teutonic Empires) and the access to ore deposits (Au, Ag, Cu, Sn, Zn, Pb, Fe) located in Alpine Mountain Ranges (i.e. End-Neolithic, Early Bronze Age). Myths like the Gilgamesh Epos and John Apocalypse convincingly reveal realistic contents relating to natural hazards like tsunamis, impact and flooding events. They unmisunderstandably make obvious that Myths may provide valuable contributions, especially to Geosciences. Some of the controlling parameters interrelate with others or present a kind of hierarchy: Mega-Volcanism/impact events à ejecta à wildfires, heat storms à cosmic winter, sint winter à stop of photosynthesis à mass extinction environmental pollution à greenhouse effects. Significant events (21 cases in total) occurred on i.e.
文摘Tinnitus is a concerning condition that affects most adults worldwide,with a prevalence of 6.7%.Theories of tinnitus have explained that an increase in spontaneous neural activity at the level of the thalamus could induce tinnitus.There are no standardized objective tests for tinnitus assessment because of its multifaceted nature.Hence,the current study aimed to explore the effect of Tinnitus on Latency and Amplitude of the Auditory Middle Latency Response in Audiological Attendees.The study recruited 50 individuals(25 normals and 25 individuals with tinnitus)who underwent audiological evaluations like Pure tone audiometry,immittance,pitch and loudness matching,THI and middle latency response.The IHS program was used to record MLR,which was obtained using tone burst stimuli of 500 Hz,1 KHz,2 KHz,and 4 KHz at a rate of 7.1/s with a constant duration of 5 ms,for a total of 1500 sweeps.As a covariate,pure tone thresholds were one of the variabilities that were addressed by ANCOVA.The amplitude of the Pa component varied significantly between the tinnitus and control groups,according to the MLR data and no other components of MLR reached that significance.Furthermore,there was no discernible variation in the latency or amplitude of MLR among any of the other components.The latency of the waveforms increased as the stimulus frequency increased.Karl Pearson correlation coefficient showed no significant correlation between THI scores and any of the outcome measures except for Pa amplitude.As the Pa component of MLR showed maximum changes between controls and individuals with tinnitus,the Pa component could be considered a potential tool for identifying neurophysiological changes related to tinnitus.
文摘BACKGROUND Middle meningeal artery embolization(MMAE)is emerging as a promising treatment for chronic subdural hematoma(CSDH),serving both as an adjunct to surgery and as a primary therapeutic option depending on patient presentation.Due to its low recurrence rate and minimal complications,MMAE has gained increasing acceptance among clinicians in recent years.This report presents a case of diplopia following MMAE due to the presence of a potential anastomotic artery,aiming to enhance awareness of this complication.CASE SUMMARY A 60-year-old male patient presented with a headache following head trauma,and cranial computed tomography revealed a left-sided CSDH.The patient underwent left MMAE;however,polyvinyl alcohol particles inadvertently flowed into the lacrimal artery through an anastomotic artery,resulting in diplopia due to impaired abduction of the left eye.The diplopia resolved by postoperative day 40.The patient’s headache resolved by postoperative day 7,and the hematoma completely resolved by postoperative day 108.CONCLUSION Potential anastomotic arteries in the middle meningeal artery(MMA)can lead to serious complications.Superselective angiography of the MMA or its branches prior to embolization is essential.Performing embolization distal to potential anastomotic sites can reduce risks,and the presence of an anastomosis may warrant coil embolization or termination of the procedure.
基金National Natural Science Foundation of China,No.42207078CUG Scholar-Scientific Research Funds at China University of Geosciences(Wuhan),No.2022166+1 种基金China Scholarship Council,No.202306410026Opening Fund of State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin,China Institute of Water Resources and Hydropower Research,No.IWHR-SKL-KF202217。
文摘Wetlands play a critical role in the global environment.The Middle Yangtze River Basin(MYRB),known for its abundant wetland resources,has experienced notable changes resulting from the complex interplay of environmental factors.Therefore,we investigated the spatiotemporal characteristics of wetland ecological quality in the MYRB from 2001 to 2020.Utilizing the random forest(RF)regression algorithm and patch-generated land-use simulation(PLUS)model,we forecasted variations in wetland habitat quality and their determinants under the Shared Socioeconomic Pathway-Representative Concentration Pathway(SSPRCP)framework from 2035 to 2095.The main findings are as follows:(1)The RF algorithm was optimal for land-use and land-cover(LULC)classification in the MYRB from 2001 to 2020,when notable changes were observed in water bodies and buildings.However,the forested area exhibited an increase and decrease of 3.9%and 1.2%under the SSP1-2.6 and SSP5-8.5 scenarios,respectively,whereas farmland exhibited a diminishing trend.(2)Wetlands were primarily concentrated in the central and eastern MYRB,with counties in the southwest exhibiting superior ecological-environmental quality from 2001 to 2020.Notably,wetland coverage revealed significantly high level,significant changes,frequent but relatively minor changes under the SSP1-2.6,SSP2-4.5,and SSP 5-8.5 scenarios,respectively.(3)Regions with lower habitat quality were primarily concentrated in urbanized areas characterized by frequent human activities,indicating a clear degradation in habitat quality across different scenarios.In conclusion,we established a foundational framework for future investigations into the eco-hydrological processes and ecosystem quality of watersheds.
基金Supported by the National Natural Science Foundation of China(42172166)National Natural Science Foundation and CNPC Joint Fund Project(U23B20154)CNPC-Southwest Petroleum University Science and Technology Cooperation Project(2020CX010000).
文摘This paper discusses the characteristics and formation mechanism of thin dolomite reservoirs in the lower submember of the second member of the Permian Maokou Formation(lower Mao 2 Member)in the Wusheng-Tongnan area of the Sichuan Basin,SW China,through comprehensive analysis of geological,geophysical and geochemical data.The reservoir rocks of the lower Mao 2 Member are dominated by porphyritic vuggy dolomite and calcareous dolomite or dolomitic limestone,which have typical karst characteristics of early diagenetic stage.The dolomites at the edge of the karst system and in the fillings have dissolved estuaries,and the dolomite breccia has micrite envelope and rim cement at the edge,indicating that dolomitization is earlier than the early diagenetic karstification.The shoal facies laminated dolomite is primarily formed by the seepage reflux dolomitization of moderate-salinity seawater.The key factors of reservoir formation are the bioclastic shoal deposition superimposed with seepgae reflux dolomitization and the karstification of early diagenetic stage,which are locally reformed by fractures and hydrothermal processes.The development of dolomite vuggy reservoir is closely related to the upward-shallowing sequence,and mainly occurs in the late highstand of the fourth-order cycle.Moreover,the size of dolomite is closely related to formation thickness,and it is concentrated in the formation thickness conversion area,followed by the thinner area.According to the understanding of insufficient accommodation space in the geomorphic highland and the migration of granular shoal to geomorphic lowland in the late highstand of the third-order cycle,it is proposed that the large-scale shoal-controlled dolomite reservoirs are distributed along structural highs and slopes,and the reservoir-forming model with shoal,dolomitization and karstification jointly controlled by the microgeomorphy and sea-level fluctuation in the sedimentary period is established.On this basis,the paleogeomorphology in the lower Mao 2 Member is restored using well-seismic data,and the reservoir distribution is predicted.The prediction results have been verified by the latest results of exploration wells and tests,which provide an important reference for the prediction of thin dolomite reservoirs under similar geological setting.
基金Supported by the Science and Technology Program of Nantong Health Committee,No.MA2019003 and No.MA2021017Kangda College of Nanjing Medical University,No.KD2021JYYJYB025,No.KD2022KYJJZD019,and No.KD2022KYJJZD022+1 种基金Research Project of Nantong Health and Health Commission,No.MS2023041the Science and Technology Program of Nantong City,No.Key003 and No.JCZ2022040.
文摘The chronic occlusion of intracranial arteries generally has no or mild clinical symptoms,and the clinical symptoms of acute cerebral artery occlusion are mostly manifested as severe cerebral infarction symptoms,which often make early diagnosis difficult,thus losing the best treatment opportunity.Once cerebral infarction occurs,the consequences are difficult to recover.This is also an important reason for the high misdiagnosis rate and mortality of this disease.In this paper,the characteristics of the disease were analyzed to provide clinical reference.
文摘Human temporal bone specimens are used in experiments to measure the sound transfer function of the middle ear.This standard method for the development of middle ear implants requires temporal bones that possess appropriate mechanical properties and structural stability and are free from pathological conditions.A laser Doppler vibrometer is commonly employed to measure the vibration of the stapes footplate.These experiments are typically conducted in the middle ear by leaving the inner ear intact,exposing the stapes footplate through the tympanic cavity,and directing the laser beam onto the footplate.However,previous studies have shown that the influence of inner ear impedance on the middle ear transfer function cannot be ignored,and any surgical manipulation may cause a change in inner ear pressure,resulting in instability in the middle ear transfer function.Therefore,this study aims to eliminate the influence of the inner ear and to establish a new experimental method in human temporal bone specimens that is more suitable for the study of sound conduction in middle ear implants.As a result,a range for middle ear transfer function was developed,which serves as a reference for assessing the conformity of temporal bone specimens to experimental standards,and the stability of this range was demonstrated under experimental conditions.
文摘BACKGROUND Picky eating is a commonly observed behavior among children globally,negatively impacting their physical and mental growth.Although common characteristics distinguish peaky eaters,including food selectivity,food neophobia,and food avoidance,there is no clear definition to assess this behavior.Due to the unavailability of data regarding picky eating,it wasn’t easy to estimate its prevalence.AIM To develop a regional protocol to help healthcare professionals identify and manage mild and moderate picky eating cases.METHODS A virtual roundtable discussion was held in April 2021 to gather the opinions of seven pediatricians and two pediatric dietitians from eight Middle Eastern countries who had great experience in the management of picky eating.The discussion covered different topics,including clearly defining mild and moderate picky eating,identifying the role of diet fortification in these cases,and the possibility of developing a systematic approach to diet fortification.RESULTS The panel identified picky eating as consuming an inadequate amount and variety of foods by rejecting familiar and unfamiliar food.Most of the time,moderate picky eating cases had micronutrient deficiencies with over-or undernutrition;the mild cases only showed inadequate food consumption and/or poor diet quality.Paying attention to the organic red flags like growth faltering and development delay and behavioral red flags,including food fixation and anticipatory gagging,will help healthcare professionals evaluate the picky eaters and the caregivers to care for their children.Although dietary supplementation and commercial food fortification play an important role in picky eating,they were no benefit in the Middle East.CONCLUSION The panel agreed that food fortification through a food-first approach and oral nutritional supplements would be the best for Middle Eastern children.These recommendations would facilitate identifying and managing picky-eating children in the Middle East.
基金supported by grants from National Natural Science Foundation of China(grant number.82301295)。
文摘Objective:To present a rare case of glial heterotopia in the middle ear occurring in association with cholesteatoma.Patient and Intervention:A 56-year-old female presented with right-sided hearing loss and otorrhea.ENT examination and CT imaging revealed middle ear cholesteatoma.Right canal wall down mastoidectomy with type Ⅲ tympanoplasty revealed a well-demarcated,soft,pinkish mass in the right middle ear without tegmen tympani dehiscence.Histopathological analysis confirmed glial heterotopia.Main Outcome Measures:Complete cholesteatoma resection,resolution of otorrhea,absence of neurological complications,and right-sided hearing improvement.Results:The patient demonstrated an uneventful postoperative recovery.At the five-month follow-up,tympanoplasty outcomes remained stable.Repeat imaging confirmed absence of skull base defects,with clinical resolution of otorrhea.No postoperative neurological complications(including cerebrospinal fluid leakage)were observed.Conclusions:Middle ear glial heterotopia is a rare entity that may be discovered incidentally or in association with infection/cholesteatoma.Definitive management requires surgical excision of the heterotopic tissue and concurrent repair of skull base bone defects when identified.Preoperative imaging evaluation with CT or MRI can be valuable to delineate anatomical relationships and exclude intracranial connections.
文摘The Middle East has long been in turmoil,and the new round of the Palestinian-Israeli conflict has further highlighted the urgency of security governance in the region.The Global Security Initiative(GSI)proposed by China provides theoretical guidance and practical paths for China’s participation in Middle East security governance.China’s engagement in Middle East security governance not only meets the expectations of Middle East countries but also fully demonstrates its responsibility as a major country,which is of great significance for China to explore participation in global security governance and address the global security deficit.
文摘Chronic subdural hematoma is essentially managed by surgical intervention.In recent times,middle meningeal artery embolisation has emerged as a less invasive procedure in such cases.The use of fine catheters to selectively embolise the specific involved branches of the middle meningeal artery using polyvinyl alcohol particles looks promising;however,the presence of anastomotic arteries can result in reflux and embolisation of these atypical branches,causing a myriad of complications.There is a need to identify these abnormal vessels in time to have a positive outcome with the least complications.
文摘Erratumto:Journal of Earth Science https://doi.org/10.1007/s12583-023-1946-6 The original version of this article unfortunately contained three mistakes.1.The presentation of Equation(4)was incorrect.The corrected one is given below.
文摘With the development of social economy,the subjects,methods,and contents of ideological and political education have undergone changes.It is not only necessary to give full play to the role of ideological and political courses but also to focus on exploring teaching forms and methods to promote the realization of the goal of“fostering virtue through education”.Under the background of the new curriculum reform,in middle school biology teaching,it is necessary to implement“fostering virtue through education”,carry out ideological and political education,effectively improve the effect of talent training,and promote the development of students’values.From the perspective of middle school biology,this paper discusses the necessity of integrating curriculum ideology and politics,analyzes the principles that should be followed in the infiltration of ideological and political elements,and puts forward specific strategies for biology teaching practice,aiming to cultivate students’good values and lay a solid foundation for their subsequent knowledge learning.
基金supported by the[National Natural Science Foundation of China]under Grant[number 12172082][Catch up with and surpass technology projects]under Grant[number 2022LCJSGC24]。
文摘Background The middle ear pneumatic system(MEPS)supports pressure balance,essential for sound conduction.Its volume and surface area are key indicators of pneumatization and ventilation,yet their specific contributions to pressure regulation need further exploration.Objective To evaluate the accuracy and sensitivity of parameters characterizing the MEPS,including volume(V),surface area(S),and surface-area-to-volume ratio(S/V),in normal ears.Materials and Methods We collected CT images of the temporal bone from 63 normal ears for this study.The volume(V),surface area(S),and surface-area-to-volume ratio(S/V)of the MEPS were measured and calculated using three-dimensional reconstruction technology.Statistical methods were used to process the data and determine the 95%reference range for the S,V,and S/V of the MEPS in the normal ear.At the same time,we analyzed the impact of differences in gender and the left and right sides on the measurements.Results The 95%reference values for the S,V,and S/V of the MEPS in normal ears were 1057.10~18239.16 mm²,609.16~9854.11 mm^(3),and 1.39~2.52 mm^(-1) respectively.There were no significant differences in the measurements between genders and between the left and right sides.Conclusions and Significance This study has established the 95%reference values for the S,V,and S/V of the MEPS in normal ears,which were 1057.10-18239.16 mm²,609.16-9854.11 mm^(3),and 1.39-2.52 mm^(-1) respectively.We found that while there is a wide variation in the V values among normal ears,there is less variability in the S/V values.This structural characteristic suggests that changes in the S/V value may have a more significant impact on the balance of middle ear pressure,and it provides important reference data for the construction and functional reconstruction of three-dimensional models of the MEPS.These findings may aid in diagnosing middle ear disorders,such as otitis media with effusion,and guide interventions to restore pressure balance.
基金financially supported by the project of the National Observation and Research Station of the Institute of Geology,China Earthquake Administration(Grant No.NORSCBS22-06)the Youth Science and Technology Development Project of the Jilin Earthquake Agency(Grant No.JZQ-202402)+1 种基金the Earthquake Science and Technology Spark Project(Grant No.XH23013B)the China Scholarship Council(Grant No.202104190014)。
文摘Cenozoic trachytes are characteristic of some active volcanic fields in China.In particular,the origin and mechanisms of the evolution of trachytes from the Tianchi(Changbaishan)volcano(TV,China/North Korea)are poorly known.Here,we present new geochronological,geochemical and isotopic data on two trachytic suites outcropping on the northern and southern upper slopes of TV.Detailed zircon laser ablation-multicollector-inductively coupled plasma-mass spectrometry(LA-MC-ICP-MS)U-Pb dating,Rb-Sr isochron dating of plagioclase and hornblende,^(40)Ar/^(39)Ar chronology with mineral chemistry,whole-rock element and Sr-Nd-Pb isotope data are used to explore their origins and evolutionary mechanisms during the late Middle Pleistocene.Our data indicate that the trachytes mainly consist of sanidine,orthoclase and plagioclase,with minor albite,quartz and hornblende.They formed at 0.353-0.346 Ma(lava flow from the northern slope)and 0.383-0.311 Ma(lava flow from the southern slope),respectively.The TV trachytes are characterized by high K_(2)O/Na_(2)O and AR values,with low A/CNK and Mg~#values.They are enriched in rare earth elements(REEs;except Eu),depleted in Sr and Ba,crystallizing at 742-858℃.The TV trachytes have high(^(87)Sr/^(86)Sr)_i values(0.70776-0.71195),positiveε_(Nd)(t)values(0.61-2.93)and radiogenic^(206)Pb/^(204)Pb values(17.515-17.806).These values are similar to those of the Pleistocene and Holocene TV trachytes.Geochemical data indicate that they were formed by fractional crystallization from a basaltic melt and assimilated upper crust material.The trace element pattern of the studied trachytes is consistent with an evolution from basaltic melts representative of an enriched mantle source.The vent from which the trachytic magma was erupted probably collapsed inside the caldera during the TV'Millennium'eruption(ME)in 946 AD.The contemporaneous emission of basaltic and trachytic magma during the Middle-Late Pleistocene suggests the coexistence of fissural basaltic volcanism and central-type trachytic volcanism,the latter of which was associated with a magma chamber in the upper crust during the TV cone-construction stage.
基金supported by the grant from The MUST Faculty Research Grants(FRG-25-031-FC)and Fundação Macao.
文摘The Silk Road witnessed the exchange,integration,and innovation of medicine between ancient China and the ancient Middle East.This article outlines a panoramic historical picture of medical interchanges between ancient China and the ancient Middle East along the Silk Road by multilingual literature research,textual criticism and scientific methods.Through the exchange of medicinal materials,the supplement of prescriptions,the reference of dosage forms,and the absorption of medical concepts,the two major medical systems along the Silk Road have interacted and integrated.Anchored in the political cooperation,sustained by translation network,and promoted by commercial intercourse,this medical dialogue shows the openness and adaptability of traditional medicine.This interchange history provides a historical paradigm for the modernization of traditional medicine,cross-cultural collaboration,and the building of the Silk Road of Health.
