Different genetic types of meter-scale cyclic sequences in stratigraphic records result from episodic accumulation of strata related to Milankovitch cycles. The distinctive fabric natures of facies succession result f...Different genetic types of meter-scale cyclic sequences in stratigraphic records result from episodic accumulation of strata related to Milankovitch cycles. The distinctive fabric natures of facies succession result from the sedimentation governed by different sediment sources and sedimentary dynamic conditions in different paleogeographical backgrounds, corresponding to high-frequency sea-level changes. Naturally, this is the fundamental criterion for the classification of genetic types of meter-scale cyclic sequences. The widespread development in stratigraphic records and the regular vertical stacking patterns in long-term sequences, the evolution characters of earth history and the genetic types reflected by specific fabric natures of facies successions in different paleogeographical settings, all that show meter-scale cyclic sequences are not only the elementary working units in stratigraphy and sedimentology, but also the replenishment and extension of parasequence of sequence stratigraphy. Two genetic kinds of facies succession for meter-scale cyclic sequence in neritic-facies strata of carbonate and clastic rocks, are normal grading succession mainly formed by tidal sedimentation and inverse grading succession chiefly made by wave sedimentation, and both of them constitute generally shallowing upward succession, the thickness of which ranges from several tens of centimeters to several meters. The classification of genetic types of meter-scale cyclic sequence could be made in terms of the fabric natures of facies succession, and carbonate meter-scale cyclic sequences could be divided into four types: L-M type, deep-water asymmetrical type, subtidal type and peritidal type. Clastic meter-scale cyclic sequences could be grouped into two types: tidal-dynamic type and wave-dynamic type. The boundaries of meter-scale cyclic sequences are marked by instantaneous punctuated surface formed by non-deposition resulting from high-frequency level changes, which include instantaneous exposed punctuated surface, drowned punctuated surface as well as their relative surface. The development of instantaneous punctuated surface used as the boundary of meter-scale cyclic sequence brings about the limitations of Walter's Law on the explanation of facies distribution in time and space, and reaffirm the importance of Sander's Rule on analysis of stratigraphic records. These non-continuous surface could be traced for long distance and some could be correlative within same basin range. The study of meter-scale cyclic sequences and their regularly vertical stacking patterns in long-term sequences indicate that the research into cyclicity of stratigraphic records is a useful way to get more regularity from stratigraphic records that are frequently complex as well as non-integrated.展开更多
The acupoints and Chinese herbal medicines are quite different in their natures. In the present paper, the authors expound the differences of the natures between the acupoints and Chinese herbal medicines from a） sub...The acupoints and Chinese herbal medicines are quite different in their natures. In the present paper, the authors expound the differences of the natures between the acupoints and Chinese herbal medicines from a） substance carriers, b） the underlying mechanism in actions, and c） individual characteristics, etc..展开更多
The study of English passive construction has always been one of the hot topics in the literature of Generative Grammar. Although many attempts have been made, the study of this structure is still not systematic enoug...The study of English passive construction has always been one of the hot topics in the literature of Generative Grammar. Although many attempts have been made, the study of this structure is still not systematic enough especially in terms of its essential natures. The present study is designed to give a full explanation of natures of English passive construction from the perspective of theta theory, which can provide English learners with a deeper understanding of passive structure.展开更多
Diagrams as a visual technique played a key role in early modern natural history.Robert Morison,a Scottish botanist and the first Professor of Botany at Oxford University,made a noteworthy early attempt in the 17th ce...Diagrams as a visual technique played a key role in early modern natural history.Robert Morison,a Scottish botanist and the first Professor of Botany at Oxford University,made a noteworthy early attempt in the 17th century to promote the use of diagrams in plant taxonomy.By pioneering the use of diagrams as the core of his botanical monographs,Morison inverted the order in which text and diagrams are read in natural history books and made diagrams more than a mere adjunct to the main text.Morison also consciously aligned the structure of the diagrams with the spatial arrangement of his seed collection and the Oxford Botanic Garden,so that the diagrams functioned productively as a means of bridging difierent botanical practices and retrieving information from multiple aspects.Morison’s appropriation and mobilisation of the diagrammatic mode of representation that originated in the Middle Ages helped pave the way for the diagram,as a visual language between textuality and pictoriality,to become prevalent amongst early modern naturalists.展开更多
“Journal of Jilin University(Science Edition)”is a comprehensive academic journal in the fields of science sponsored by Jilin University and administrated by the Ministry of Education of the Peoples Republic of Chin...“Journal of Jilin University(Science Edition)”is a comprehensive academic journal in the fields of science sponsored by Jilin University and administrated by the Ministry of Education of the Peoples Republic of China.The journal started publication in 1955.The original name at starting publication was “Journal of Natural Science of Northeast People University”,which was changed into “Acta Scientiarum Naturalium Universitatis Jilinensis”in 1958owing to the name change of the university.The present journal name has been begun since the beginning of 2002after a new Jilin University was set up,which comes from the amalgamation of the original Jilin University,Jilin University of Technology,Bethune Medicine University,Changchun University of Science and Technology and Changchun Post and Telecommunication Institute on June 12,2000.The domestic journal number is CN 22-1340/O,and the international journal number is ISSN 1671-5489.展开更多
The rise in urbanization has increasingly restricted access to natural environments,posing substantial risks to the physical and mental health of urban populations,including university students and other high-stress g...The rise in urbanization has increasingly restricted access to natural environments,posing substantial risks to the physical and mental health of urban populations,including university students and other high-stress groups.This study examines the comparative effects of outdoor forest meditation(OFM)and indoor nature meditation(INM)in simulated nature environments(SNEs)on the physiological and psychological health of university students.A pretestposttest repeated measures design was employed,with 40students participating in three replicated OFM sessions and three identical INM sessions across varied SNE settings.Key physiological metrics,including heart rate(HR),blood pressure(BP),and salivary amylase concentration(SAC),were measured before and after each session.Psychological well-being was assessed using the Perceived Stress Scale-10(PSS-10)and Profile of Mood States(POMS).Results revealed significant reductions(p<0.05)in most post-intervention outcomes,except in the second indoor session across physiologic al and psychologic al responses,while multi-sensory INM sessions produced comparable benefits.Notably,SNEs with enhanced sensory components were effective,though slightly less impactful than OFM.These findings suggest that both OFM in nature and INM in SNEs can benefit university students'well-being.INM in SNEs offers a promising alternative for those with limited access to natural settings,contributing meaningfully to stress reduction and overall well-being.This study highlights the potential for nature-based strategies for human health in urban centres,advocating for further investigation into the long-term impacts of SNEs and optimal sensory configurations for maximizing therapeutic effects in urban populations.展开更多
CHINA.Dinghu Mountain National Nature Reserve.Located in Zhaoqing,Guangdong Province,Dinghu Mountain National Nature Reserve is a pristine natural sanctuary spanning 1,133 hectares within the low mountain ranges of th...CHINA.Dinghu Mountain National Nature Reserve.Located in Zhaoqing,Guangdong Province,Dinghu Mountain National Nature Reserve is a pristine natural sanctuary spanning 1,133 hectares within the low mountain ranges of the Dayunwu Mountains.展开更多
In a superconductor embedded with a quantum magnetic impurity,the Kondo effect is involved,leading to the competition between the Kondo singlet phase and the superconductivity phase.By means of the natural orbitals re...In a superconductor embedded with a quantum magnetic impurity,the Kondo effect is involved,leading to the competition between the Kondo singlet phase and the superconductivity phase.By means of the natural orbitals renormalization group(NORG)method,we revisit the problem of a quantum magnetic impurity coupled with a conventional s-wave superconductor.Here we present a detailed study focusing on the impurity spin polarization and susceptibility,the Kondo screening cloud,as well as the number and structures of the active natural orbitals(ANOs).In the superconducting phase,the impurity spin is partially polarized,indicating that the impurity remains partially screened by the quantum fluctuations.Furthermore,the impurity spin susceptibility becomes divergent,resulting from the presence of residual local moment formed at the impurity site.Correspondingly,a non-integral(incomplete)Kondo cloud is formed,although the ground state is a spin doublet in this phase.In comparison,the Kondo cloud is complete in the Kondo singlet phase as expected.We also quantify the critical point,where the quantum phase transition from a Kondo singlet phase to a superconducting phase occurs,which is consistent with that in previous works.On the other hand,it is illustrated that only one ANO emerges in both quantum phases.The structures of the ANO,projected into both the real space and momentum space,are distinct in the Kondo singlet phase from that in the superconducting phase.More specifically,in the Kondo singlet phase,the ANO keeps fully active with half-occupied,and the superconducting gap has negligible influence on its structure.On the contrary,in the superconducting phase,the ANO tends to be inactive and its structure changes significantly as the superconducting gap increases.Additionally,our investigation demonstrates that the NORG method is reliable and convenient to solve the quantum impurity problems in superconductors as well,which will promote further theoretical studies on the Kondo problems in such systems using numerical methods.展开更多
Located in southern Ningxia Hui Autonomous Region,northwest China,the Liupan Mountain National Nature Reserve covers a total area of 26,783.64 hectares.Established in 1982 and upgraded to national status in 1988,it pr...Located in southern Ningxia Hui Autonomous Region,northwest China,the Liupan Mountain National Nature Reserve covers a total area of 26,783.64 hectares.Established in 1982 and upgraded to national status in 1988,it protects a vital temperate mountainous forest ecosystem on the Loess Plateau.The reserve is centred around the Liupan Mountain range,one of China’s youngest mountain chains,formed by Himalayan tectonic movements.展开更多
The modern world remains vulnerable to natural disasters,including floods,earthquakes,wildfires,and others.These events remain unpredictable and inevitable,and recovering quickly and effectively requires significant e...The modern world remains vulnerable to natural disasters,including floods,earthquakes,wildfires,and others.These events remain unpredictable and inevitable,and recovering quickly and effectively requires significant effort and expense.Monitoring is becoming more efficient thanks to technologies such as Unmanned Aerial Vehicles(UAVs),which can access hard-to-reach areas and provide real-time data.However,in disaster-affected areas,these monitoring systems may encounter many obstacles when communicating with servers or transmitting monitored data.This paper proposes an adaptive communication model to overcome the challenges faced in disaster-affected areas.A base station is responsible for collecting data(such as images and videos)captured by UAVs performing surveillance within its communication range.This station is typically a tower providing fixed cellular network service.However,in the absence of such a tower,a selected UAV may serve as the station,depending on the situation.If surveillance needs to be performed outside the coverage area,it can continue to communicate via nearby UAVs through cooperative communication.UAVs with internet support,known as the Internet of Flying Things(IoFT),will also be utilized to enhance communication capacity and efficiency.The proposed communication model is validated through experiments,showing superior data transmission performance and higher throughput.Analysis indicates it outperforms traditional systems,even in rural areas,with or without internet access.展开更多
Knee osteoarthritis(KOA)is a prevalent chronic degenerative joint disorder characterized by an imbalance between articular cartilage degradation and synthesis,a central mechanism in KOA pathogenesis.Given the absence ...Knee osteoarthritis(KOA)is a prevalent chronic degenerative joint disorder characterized by an imbalance between articular cartilage degradation and synthesis,a central mechanism in KOA pathogenesis.Given the absence of disease-modifying therapies,there is a critical need to elucidate the underlying pathological processes,establish reliable biomarkers for early detection and prognosis,and identify safer,more effective therapeutic agents.In recent years,natural products have attracted considerable interest due to their low toxicity,cost-effectiveness,and distinct biological activities,demonstrating significant potential in KOA management.These compounds can impede KOA progression through multiple mechanisms,including promoting cartilage matrix synthesis,mitigating inflammation,reducing oxidative stress,suppressing chondrocyte apoptosis,and modulating autophagy,thereby supporting their translational application.This review summarizes biomarkers relevant to early diagnosis and phenotypic stratification in KOA,with a focus on elucidating the pharmacological actions and molecular mechanisms of natural products,such as flavonoids,alkaloids,saponins,terpenes,and traditional Chinese medicine(TCM)formulas,in KOA intervention,aiming to provide evidence-based strategies for improved disease management.展开更多
I was 26 the first time I travelled to China,and even now,it feels like an unexpected chapter in my life.The opportunity came out of the blue.I learned,just a month before departure,that I had been selected for a one-...I was 26 the first time I travelled to China,and even now,it feels like an unexpected chapter in my life.The opportunity came out of the blue.I learned,just a month before departure,that I had been selected for a one-month professional training programme.The news ignited a wave of excitement.For nearly two weeks,I stayed up late into the night,imagining a country I had never seen,trying to picture what China might really be like,beyond the images in books,films and media.展开更多
CHINA Wuliangshan National Nature Reserve Spanning a significant altitudinal range from 1,600 to 3,371 metres and encompassing a total area of 31,585 hectares,the Wuliangshan National Nature Reserve protects one of th...CHINA Wuliangshan National Nature Reserve Spanning a significant altitudinal range from 1,600 to 3,371 metres and encompassing a total area of 31,585 hectares,the Wuliangshan National Nature Reserve protects one of the most intact and pristine forest ecosystems in southern Yunnan Province.展开更多
Osteoporosis is a systemic skeletal disorder characterized by reduced bone mass,compromised bone microstructure,and an increased risk of fractures,primarily due to excessive osteoclast-mediated bone resorption relativ...Osteoporosis is a systemic skeletal disorder characterized by reduced bone mass,compromised bone microstructure,and an increased risk of fractures,primarily due to excessive osteoclast-mediated bone resorption relative to osteoblast-mediated bone formation.While current anti-osteoporosis drugs,such as bisphosphonates and denosumab,predominantly focus on reducing bone resorption,osteoanabolic approaches are essential for restoring bone microarchitecture and ultimately reducing fracture risk.Traditional Chinese medicines(TCMs)and their active ingredients have long been used in China for osteoporosis prevention and treatment.This review provides a comprehensive evaluation of the effects and molecular mechanisms of 65 natural products across 24 categories on osteoblast-mediated bone formation.These compounds promote bone formation by regulating key transcription factors(RUNX2 and Osterix)and signaling pathways,including WNT/β-catenin,bone morphogenic protein(BMP),mitogen-activated protein kinase(MAPK),phosphoinositide 3-kinase/protein kinase B(PI3K/AKT),oxidative stress,autophagy,and epigenetic regulation.Notably,certain natural products[e.g.,icariin(ICA)]exert their effects through multiple targets and pathways.Many of these natural products have demonstrated significant therapeutic efficacy in animal models,such as ovariectomized(OVX)mice.Our findings suggest that natural products with kidney-tonifying,anti-inflammatory,and antioxidant properties,as well as those inhibiting adipocyte differentiation,may hold promise for osteoporosis treatment.Additionally,we highlight current research gaps and propose future directions,including high-throughput screening and validation in diverse animal models,development of novel bone-targeting delivery systems,and identification of natural compounds targeting osteocytes.展开更多
Gazetteer of Garze’s Natural Scenery This book is divided into five chapters,provides a comprehensive exploration of the geographical features and cultural context surrounding the thirteen renowned mountains,five maj...Gazetteer of Garze’s Natural Scenery This book is divided into five chapters,provides a comprehensive exploration of the geographical features and cultural context surrounding the thirteen renowned mountains,five major rivers,as well as numerous lakes,glaciers,and ancient trails within Garze Tibetan Autonomous Prefecture,Sichuan Province.By combining academic rigor with accessibility and substantial documentary value,it allows readers to survey all of Garze with a single volume in hand.Published by the Local Records Publishing House.展开更多
For decades,Xu has been committed to fulfilling the duty and mission of a scientist and educator—diving into the laws of nature,caring deeply for the nation,and earnestly cultivating younger generations.
Mesenchymal stem cells(MSCs)are pluripotent stem cells isolated from human tissues.Due to their strong self-renewal capacity,pluripotency,and immunomodulatory properties,MSCs have garnered significant attention in cel...Mesenchymal stem cells(MSCs)are pluripotent stem cells isolated from human tissues.Due to their strong self-renewal capacity,pluripotency,and immunomodulatory properties,MSCs have garnered significant attention in cell therapy and tissue regeneration.However,cellular senescence induced by replication or external stimuli can impair MSC proliferation and differentiation,making it crucial to develop interventions that delay or reverse the senescence process.From a traditional Chinese medicine perspective,senescence stems from spleen and stomach deficiency,kidney deficiency,and related factors;thus,medicines that tonify the kidney and promote Qi and blood circulation play vital roles in anti-senescence therapy.Chinese medicine,characterized by low toxicity and multi-target,multi-functional properties,has become prominent in anti-senescence research.This paper examines the MSC senescence process by discussing its causes,characteristics,and mechanisms,then summarizes how active ingredients in herbal medicines and natural compounds reverse MSC senescence,facilitating the discovery of additional anti-senescence Chinese medicines and their effective components.展开更多
Natural product(NPT)derived from traditional Chinese medicine has a rich history as an integral part of Chinese healthcare for thousands of years.Recently,the application of NPT in sonodynamic antibacterial therapy(SD...Natural product(NPT)derived from traditional Chinese medicine has a rich history as an integral part of Chinese healthcare for thousands of years.Recently,the application of NPT in sonodynamic antibacterial therapy(SDAT)has emerged as a promising area of research.This perspective summarizes the recent NPT-based sonosensitizers in SDAT.Currently,common NPT-based sonosensitizers include curcumin,chlorophyll derivatives,hypericin,and berberine.Compared with other sonosensitizers,natural sources of NPT-based sonosensitizers with reactive oxide species production performance under ultrasound conditions,low biotoxicity,and other additional biological activity make them have application prospects in bacterial removal.Finally,the potential benefits and challenges of NPT-based nanosonosensitizers were also discussed.展开更多
基金ThestudyisjointlysupportedbyNationalNaturalScienceFoundationofChina (No .4980 2 0 1 2 )andMinistryofSciencesandTechnology (SSER
文摘Different genetic types of meter-scale cyclic sequences in stratigraphic records result from episodic accumulation of strata related to Milankovitch cycles. The distinctive fabric natures of facies succession result from the sedimentation governed by different sediment sources and sedimentary dynamic conditions in different paleogeographical backgrounds, corresponding to high-frequency sea-level changes. Naturally, this is the fundamental criterion for the classification of genetic types of meter-scale cyclic sequences. The widespread development in stratigraphic records and the regular vertical stacking patterns in long-term sequences, the evolution characters of earth history and the genetic types reflected by specific fabric natures of facies successions in different paleogeographical settings, all that show meter-scale cyclic sequences are not only the elementary working units in stratigraphy and sedimentology, but also the replenishment and extension of parasequence of sequence stratigraphy. Two genetic kinds of facies succession for meter-scale cyclic sequence in neritic-facies strata of carbonate and clastic rocks, are normal grading succession mainly formed by tidal sedimentation and inverse grading succession chiefly made by wave sedimentation, and both of them constitute generally shallowing upward succession, the thickness of which ranges from several tens of centimeters to several meters. The classification of genetic types of meter-scale cyclic sequence could be made in terms of the fabric natures of facies succession, and carbonate meter-scale cyclic sequences could be divided into four types: L-M type, deep-water asymmetrical type, subtidal type and peritidal type. Clastic meter-scale cyclic sequences could be grouped into two types: tidal-dynamic type and wave-dynamic type. The boundaries of meter-scale cyclic sequences are marked by instantaneous punctuated surface formed by non-deposition resulting from high-frequency level changes, which include instantaneous exposed punctuated surface, drowned punctuated surface as well as their relative surface. The development of instantaneous punctuated surface used as the boundary of meter-scale cyclic sequence brings about the limitations of Walter's Law on the explanation of facies distribution in time and space, and reaffirm the importance of Sander's Rule on analysis of stratigraphic records. These non-continuous surface could be traced for long distance and some could be correlative within same basin range. The study of meter-scale cyclic sequences and their regularly vertical stacking patterns in long-term sequences indicate that the research into cyclicity of stratigraphic records is a useful way to get more regularity from stratigraphic records that are frequently complex as well as non-integrated.
文摘The acupoints and Chinese herbal medicines are quite different in their natures. In the present paper, the authors expound the differences of the natures between the acupoints and Chinese herbal medicines from a） substance carriers, b） the underlying mechanism in actions, and c） individual characteristics, etc..
文摘The study of English passive construction has always been one of the hot topics in the literature of Generative Grammar. Although many attempts have been made, the study of this structure is still not systematic enough especially in terms of its essential natures. The present study is designed to give a full explanation of natures of English passive construction from the perspective of theta theory, which can provide English learners with a deeper understanding of passive structure.
文摘Diagrams as a visual technique played a key role in early modern natural history.Robert Morison,a Scottish botanist and the first Professor of Botany at Oxford University,made a noteworthy early attempt in the 17th century to promote the use of diagrams in plant taxonomy.By pioneering the use of diagrams as the core of his botanical monographs,Morison inverted the order in which text and diagrams are read in natural history books and made diagrams more than a mere adjunct to the main text.Morison also consciously aligned the structure of the diagrams with the spatial arrangement of his seed collection and the Oxford Botanic Garden,so that the diagrams functioned productively as a means of bridging difierent botanical practices and retrieving information from multiple aspects.Morison’s appropriation and mobilisation of the diagrammatic mode of representation that originated in the Middle Ages helped pave the way for the diagram,as a visual language between textuality and pictoriality,to become prevalent amongst early modern naturalists.
文摘“Journal of Jilin University(Science Edition)”is a comprehensive academic journal in the fields of science sponsored by Jilin University and administrated by the Ministry of Education of the Peoples Republic of China.The journal started publication in 1955.The original name at starting publication was “Journal of Natural Science of Northeast People University”,which was changed into “Acta Scientiarum Naturalium Universitatis Jilinensis”in 1958owing to the name change of the university.The present journal name has been begun since the beginning of 2002after a new Jilin University was set up,which comes from the amalgamation of the original Jilin University,Jilin University of Technology,Bethune Medicine University,Changchun University of Science and Technology and Changchun Post and Telecommunication Institute on June 12,2000.The domestic journal number is CN 22-1340/O,and the international journal number is ISSN 1671-5489.
基金funded by UBC Forest and Human Wellbeing Research(Grant No.GR020223)。
文摘The rise in urbanization has increasingly restricted access to natural environments,posing substantial risks to the physical and mental health of urban populations,including university students and other high-stress groups.This study examines the comparative effects of outdoor forest meditation(OFM)and indoor nature meditation(INM)in simulated nature environments(SNEs)on the physiological and psychological health of university students.A pretestposttest repeated measures design was employed,with 40students participating in three replicated OFM sessions and three identical INM sessions across varied SNE settings.Key physiological metrics,including heart rate(HR),blood pressure(BP),and salivary amylase concentration(SAC),were measured before and after each session.Psychological well-being was assessed using the Perceived Stress Scale-10(PSS-10)and Profile of Mood States(POMS).Results revealed significant reductions(p<0.05)in most post-intervention outcomes,except in the second indoor session across physiologic al and psychologic al responses,while multi-sensory INM sessions produced comparable benefits.Notably,SNEs with enhanced sensory components were effective,though slightly less impactful than OFM.These findings suggest that both OFM in nature and INM in SNEs can benefit university students'well-being.INM in SNEs offers a promising alternative for those with limited access to natural settings,contributing meaningfully to stress reduction and overall well-being.This study highlights the potential for nature-based strategies for human health in urban centres,advocating for further investigation into the long-term impacts of SNEs and optimal sensory configurations for maximizing therapeutic effects in urban populations.
文摘CHINA.Dinghu Mountain National Nature Reserve.Located in Zhaoqing,Guangdong Province,Dinghu Mountain National Nature Reserve is a pristine natural sanctuary spanning 1,133 hectares within the low mountain ranges of the Dayunwu Mountains.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.12104247 and 11934020)。
文摘In a superconductor embedded with a quantum magnetic impurity,the Kondo effect is involved,leading to the competition between the Kondo singlet phase and the superconductivity phase.By means of the natural orbitals renormalization group(NORG)method,we revisit the problem of a quantum magnetic impurity coupled with a conventional s-wave superconductor.Here we present a detailed study focusing on the impurity spin polarization and susceptibility,the Kondo screening cloud,as well as the number and structures of the active natural orbitals(ANOs).In the superconducting phase,the impurity spin is partially polarized,indicating that the impurity remains partially screened by the quantum fluctuations.Furthermore,the impurity spin susceptibility becomes divergent,resulting from the presence of residual local moment formed at the impurity site.Correspondingly,a non-integral(incomplete)Kondo cloud is formed,although the ground state is a spin doublet in this phase.In comparison,the Kondo cloud is complete in the Kondo singlet phase as expected.We also quantify the critical point,where the quantum phase transition from a Kondo singlet phase to a superconducting phase occurs,which is consistent with that in previous works.On the other hand,it is illustrated that only one ANO emerges in both quantum phases.The structures of the ANO,projected into both the real space and momentum space,are distinct in the Kondo singlet phase from that in the superconducting phase.More specifically,in the Kondo singlet phase,the ANO keeps fully active with half-occupied,and the superconducting gap has negligible influence on its structure.On the contrary,in the superconducting phase,the ANO tends to be inactive and its structure changes significantly as the superconducting gap increases.Additionally,our investigation demonstrates that the NORG method is reliable and convenient to solve the quantum impurity problems in superconductors as well,which will promote further theoretical studies on the Kondo problems in such systems using numerical methods.
文摘Located in southern Ningxia Hui Autonomous Region,northwest China,the Liupan Mountain National Nature Reserve covers a total area of 26,783.64 hectares.Established in 1982 and upgraded to national status in 1988,it protects a vital temperate mountainous forest ecosystem on the Loess Plateau.The reserve is centred around the Liupan Mountain range,one of China’s youngest mountain chains,formed by Himalayan tectonic movements.
文摘The modern world remains vulnerable to natural disasters,including floods,earthquakes,wildfires,and others.These events remain unpredictable and inevitable,and recovering quickly and effectively requires significant effort and expense.Monitoring is becoming more efficient thanks to technologies such as Unmanned Aerial Vehicles(UAVs),which can access hard-to-reach areas and provide real-time data.However,in disaster-affected areas,these monitoring systems may encounter many obstacles when communicating with servers or transmitting monitored data.This paper proposes an adaptive communication model to overcome the challenges faced in disaster-affected areas.A base station is responsible for collecting data(such as images and videos)captured by UAVs performing surveillance within its communication range.This station is typically a tower providing fixed cellular network service.However,in the absence of such a tower,a selected UAV may serve as the station,depending on the situation.If surveillance needs to be performed outside the coverage area,it can continue to communicate via nearby UAVs through cooperative communication.UAVs with internet support,known as the Internet of Flying Things(IoFT),will also be utilized to enhance communication capacity and efficiency.The proposed communication model is validated through experiments,showing superior data transmission performance and higher throughput.Analysis indicates it outperforms traditional systems,even in rural areas,with or without internet access.
基金supported by the National Science Foundation of China(No.82474144)the Zhejiang Province Technological Leading Talents Fund Project(No.2022R52031)。
文摘Knee osteoarthritis(KOA)is a prevalent chronic degenerative joint disorder characterized by an imbalance between articular cartilage degradation and synthesis,a central mechanism in KOA pathogenesis.Given the absence of disease-modifying therapies,there is a critical need to elucidate the underlying pathological processes,establish reliable biomarkers for early detection and prognosis,and identify safer,more effective therapeutic agents.In recent years,natural products have attracted considerable interest due to their low toxicity,cost-effectiveness,and distinct biological activities,demonstrating significant potential in KOA management.These compounds can impede KOA progression through multiple mechanisms,including promoting cartilage matrix synthesis,mitigating inflammation,reducing oxidative stress,suppressing chondrocyte apoptosis,and modulating autophagy,thereby supporting their translational application.This review summarizes biomarkers relevant to early diagnosis and phenotypic stratification in KOA,with a focus on elucidating the pharmacological actions and molecular mechanisms of natural products,such as flavonoids,alkaloids,saponins,terpenes,and traditional Chinese medicine(TCM)formulas,in KOA intervention,aiming to provide evidence-based strategies for improved disease management.
文摘I was 26 the first time I travelled to China,and even now,it feels like an unexpected chapter in my life.The opportunity came out of the blue.I learned,just a month before departure,that I had been selected for a one-month professional training programme.The news ignited a wave of excitement.For nearly two weeks,I stayed up late into the night,imagining a country I had never seen,trying to picture what China might really be like,beyond the images in books,films and media.
文摘CHINA Wuliangshan National Nature Reserve Spanning a significant altitudinal range from 1,600 to 3,371 metres and encompassing a total area of 31,585 hectares,the Wuliangshan National Nature Reserve protects one of the most intact and pristine forest ecosystems in southern Yunnan Province.
基金supported by the National Natural Science Foundation of China(No.31800059)。
文摘Osteoporosis is a systemic skeletal disorder characterized by reduced bone mass,compromised bone microstructure,and an increased risk of fractures,primarily due to excessive osteoclast-mediated bone resorption relative to osteoblast-mediated bone formation.While current anti-osteoporosis drugs,such as bisphosphonates and denosumab,predominantly focus on reducing bone resorption,osteoanabolic approaches are essential for restoring bone microarchitecture and ultimately reducing fracture risk.Traditional Chinese medicines(TCMs)and their active ingredients have long been used in China for osteoporosis prevention and treatment.This review provides a comprehensive evaluation of the effects and molecular mechanisms of 65 natural products across 24 categories on osteoblast-mediated bone formation.These compounds promote bone formation by regulating key transcription factors(RUNX2 and Osterix)and signaling pathways,including WNT/β-catenin,bone morphogenic protein(BMP),mitogen-activated protein kinase(MAPK),phosphoinositide 3-kinase/protein kinase B(PI3K/AKT),oxidative stress,autophagy,and epigenetic regulation.Notably,certain natural products[e.g.,icariin(ICA)]exert their effects through multiple targets and pathways.Many of these natural products have demonstrated significant therapeutic efficacy in animal models,such as ovariectomized(OVX)mice.Our findings suggest that natural products with kidney-tonifying,anti-inflammatory,and antioxidant properties,as well as those inhibiting adipocyte differentiation,may hold promise for osteoporosis treatment.Additionally,we highlight current research gaps and propose future directions,including high-throughput screening and validation in diverse animal models,development of novel bone-targeting delivery systems,and identification of natural compounds targeting osteocytes.
文摘Gazetteer of Garze’s Natural Scenery This book is divided into five chapters,provides a comprehensive exploration of the geographical features and cultural context surrounding the thirteen renowned mountains,five major rivers,as well as numerous lakes,glaciers,and ancient trails within Garze Tibetan Autonomous Prefecture,Sichuan Province.By combining academic rigor with accessibility and substantial documentary value,it allows readers to survey all of Garze with a single volume in hand.Published by the Local Records Publishing House.
文摘For decades,Xu has been committed to fulfilling the duty and mission of a scientist and educator—diving into the laws of nature,caring deeply for the nation,and earnestly cultivating younger generations.
基金supported by Zhejiang Provincial Natural Science Foundation of China(No.LQ23H290006)the National Natural Science Foundation of China(No.82204781)+2 种基金the Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province(No.2020E10021)Zhejiang Provincial Program for the Cultivation of High-level Innovative Health Talents(No.ZWB-2020-18)Zhejiang Provincial Traditional Chinese Medicine Science and Technology Project(No.2023ZR119).
文摘Mesenchymal stem cells(MSCs)are pluripotent stem cells isolated from human tissues.Due to their strong self-renewal capacity,pluripotency,and immunomodulatory properties,MSCs have garnered significant attention in cell therapy and tissue regeneration.However,cellular senescence induced by replication or external stimuli can impair MSC proliferation and differentiation,making it crucial to develop interventions that delay or reverse the senescence process.From a traditional Chinese medicine perspective,senescence stems from spleen and stomach deficiency,kidney deficiency,and related factors;thus,medicines that tonify the kidney and promote Qi and blood circulation play vital roles in anti-senescence therapy.Chinese medicine,characterized by low toxicity and multi-target,multi-functional properties,has become prominent in anti-senescence research.This paper examines the MSC senescence process by discussing its causes,characteristics,and mechanisms,then summarizes how active ingredients in herbal medicines and natural compounds reverse MSC senescence,facilitating the discovery of additional anti-senescence Chinese medicines and their effective components.
基金supported by the Innovation and Entrepreneurship Training Program for College Students(X2025102911746,X2025102910483).
文摘Natural product(NPT)derived from traditional Chinese medicine has a rich history as an integral part of Chinese healthcare for thousands of years.Recently,the application of NPT in sonodynamic antibacterial therapy(SDAT)has emerged as a promising area of research.This perspective summarizes the recent NPT-based sonosensitizers in SDAT.Currently,common NPT-based sonosensitizers include curcumin,chlorophyll derivatives,hypericin,and berberine.Compared with other sonosensitizers,natural sources of NPT-based sonosensitizers with reactive oxide species production performance under ultrasound conditions,low biotoxicity,and other additional biological activity make them have application prospects in bacterial removal.Finally,the potential benefits and challenges of NPT-based nanosonosensitizers were also discussed.
